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Datasheet of CLR1501
Description: CLR1501 is a synthetic analogs of the tumor-targeting agent alkylphosphocholine (APC), which is specifically attracted to cancer cells. CLR1501 is molecularly altered to carry fluorescent dyes that glow under lights with specific wavelength in the green (CLR1501) . Viewed under appropriate conditions, CLR1501 dye makes tumor cells "light up" so that it can be readily distinguished from neighboring normal brain tissue.The results confirmed that CLR150 was attracted to tumor cells, and emitted light of specific wavelengths under appropriate imaging conditions. Both APC analogs provided "excellent fluorescence discrimination of tumor from adjacent normal brain." Tumors could be clearly seen using different types of commercially available imaging systems. Imaging with CLR1501 green dye showed fluorescence similar to that achieved with currently used 5-ALA dye. The use of near-infrared fluorescence would offer additional advantages during actual surgery, compared to fluorescence in the visible-light range.
.Chemical Information Catalog
DC9797
Purity of current batch:
>98%
Molecular Weight (MW)
701.43
Molecular Formula
C38H59BF2N3O4P
CAS No.
N/A
Solubility (25°C)
DMSO
Storage
Store at -20°C (desiccating conditions).
Handling: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months. Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.