JANUARY 2022 Southwest Retort

Page 8

From the ACS Press Room

People with IBD have more Microplastics in Their Feces, Study Says “Analysis of Microplastics in Human Feces Reveals a Correlation between Fecal Microplastics and Inflammatory Bowel Disease Status”

different geographic regions of China. Analysis of the samples showed that feces from IBD patients contained about 1.5 times more microplastic particles per gram than those from healthy subjects. The microplastics had Environmental Science & Technology similar shapes (mostly sheets and fibers) in Microplastics — tiny pieces of plastic less the two groups, but the IBD feces had more than 5 mm in length — are everywhere, from small (less than 50 μm) particles. The two bottled water to food to air. According to re- most common types of plastic in both groups cent estimates, people consume tens of thou- were polyethylene terephthalate (PET; used sands of these particles each year, with un- in bottles and food containers) and polyamknown health consequences. Now, research- ide (PA; found in food packaging and texers reporting in ACS’ Environmental Scitiles). Peoence & Technology found that people with ple with inflammatory bowel disease (IBD) have more severe more microplastics in their feces than healthy IBD sympcontrols, suggesting that the fragments could toms tended be related to the disease process. to have higher levThe prevalence of IBD, which includes Crohn’s disease and ulcerative colitis, is ris- els of fecal microplastics. Through a quesing globally. Characterized by chronic in- tionnaire, the researchers found that people in flammation of the digestive tract, IBD can be both groups who drank bottled water, ate triggered or made worse by diet and environ- takeaway food and were often exposed to mental factors. Microplastics can cause intes- dust had more microplastics in their feces. tinal inflammation, gut microbiome disturb- These results suggest that people with IBD ances and other problems in animal models, may be exposed to more microplastics in so Faming Zhang, Yan Zhang and colleagues their gastrointestinal tract. However, it’s still wondered if they could also contribute to unclear whether this exposure could cause or IBD. As a first step toward finding out, the contribute to IBD, or whether people with researchers wanted to compare the levels of IBD accumulate more fecal microplastics as microplastics in feces from healthy subjects a result of their disease, the researcher say. and people with different severities of IBD. The authors acknowledge funding from The team obtained fecal samples from 50 the National Natural Science Foundation of healthy people and 52 people with IBD from China. January 2022

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