10/5/2019
Certificate In Directed Evolution: Engineering Biocatalysts - Edukite
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Certi cate In Directed Evolution: Engineering Biocatalysts ( 8 REVIEWS )
538 STUDENTS
Directed evolution, a method used in protein engineering, is used to produce enzymes with many unique properties. The method mimics …
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1 YEAR LEVEL 2 - CERTIFICATE COURSE BADGE COURSE CERTIFICATE
14
NUMBER OF UNITS NUMBER OF QUIZZES
0
2 HOURS, 50 MINUTES
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Directed evolution, a method used in protein engineering, is used to produce enzymes with many unique properties. The method mimics the process of natural selection to evolve proteins or nucleic acids toward a user-de ned goal. The whole process is divided into two parts – mutagenesis of the gene encoding the enzyme to produce a library of variants, and selection of a particular variant based on its desirable catalytic properties. The Certi cate In Directed Evolution: Engineering Biocatalysts course focuses on the process of Directed evolution and analyses the enzymes types that are worth evolving. You will learn the methods that are used for library generation and enzyme selection. The enzymes that are used in the synthesis of drugs and biotechnological applications will also be focused on the course.
Assessment This course does not involve any written exams. Students need to answer 5 assignment questions to complete the course, the answers will be in the form of written work in pdf or word. Students can write the answers in their own time. Each answer needs to be 200 words (1 Page). Once the answers are submitted, the tutor will check and assess the work.
Certification Edukite courses are free to study. To successfully complete a course you must submit all the assignment of the course as part of assessment. Upon successful completion of a course, you can choose to make your achievement formal by obtaining your Certi cate at a cost of £49. https://edukite.org/course/certificate-in-directed-evolution-engineering-biocatalysts/
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COURSE CURRICULUM
Introduction
00:10:00
Library generation by point mutation
00:15:00
Library generation by recombination
00:15:00
Alternative methods for library generation
00:15:00
Enzyme evolution by genetic complementation
00:10:00
Enzyme evolution by chemical complementation
00:20:00
Enzyme evolution using phage display
00:15:00
Enzyme evolution using bacterial cell surface display
00:10:00
Enzyme evolution using yeast surface display
00:10:00
Enzyme evolution using ribosome display
00:15:00
Enzyme evolution by in vitro compartmentalization
00:15:00
Alternative methods for enzyme/catalyst design
00:20:00
00:00:00
Assessment
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