Recent Advances in Pituitary Medicine

PL-Endo

Ken K. Y. Ho

Centres for Health Research, Princess Alexandra Hospital and the University of Queensland, Brisbane, Queensland, Australia

The last decade(s) has seen major developments in molecular genetics, cell biology, systems biology, pharmacotherapy and information technology collectively bringing major advances to all areas of medicine. This is no more evident than in pituitary medicine. My presentation will focus on major contributions in the literature in the last 2 years. The material spans basic to clinical advances across pathogenesis, epidemiology and therapy of pituitary disease. The selection includes elucidating the causation of craniopharyngiomas, identification of prolactin receptor defect phenotype, understanding the basis of pituitary tumour senesence, therapeutic perspectives for acromegaly, Cushing’s Disease and adult hyposomatotrophism and uncovering a pathogenic link between prolactin and post-partum cardiac dysfunction.