MTP-D：Meet the Professor-Diabetes (1

MTP-D MANAGEMENT OF OBESITY

K-C HUANG

1Department of Family Medicine, National Taiwan University Hospital, Taiwan, R.O.C.

Obesity is related to many comorbidities such as type 2 diabetes, hypertension, dyslipidemia, obstructive sleep apnea, non-alcoholic fatty liver diseases, osteoarthritis, and some kinds of cancer. Furthermore, obesity per se also increases all-causes mortality. Furthermore, the prevalence of obesity increases thereby it becomes a worldwide health problem. Appropriate weight reduction can reduce the obesity-related health burden. Lifestyle modification remains the core stone in the management of obesity. Restricted balanced diet and increased physical activity are encouraged in stages of weight reduction and maintenance. Pharmacotherapy may be considered if subjects are suffered from obesityrelated comorbidities or high degree of obesity. In Taiwan, Xenical and Saxenda are two available antiobesity drugs. Weight change issue should be also assessed in advance when managing comorbidities. Bariatric surgery is indicated if the subjects fail to reduce adequate body weight with lifestyle modification and pharmacotherapy. In the future, long acting or oral form GLP-1 agonists or other gut hormones will be on the market to assist obese people to control their body weight.