THE JOURNEY OF MEDICINE FROM LAB TO SHELF EVASIONE SHEDIR PHARMA
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Every year, many drugs are trialed and licensed to treat many diseases and illnesses all over the world. The pharmaceutical companies work on many drugs and put them on trials for many years to provide a safe and effective drug for patients.
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Despite all these efforts, a small percentage of the medicine discovered by scientists makes it to the market. To research and develop many drugs often take years and a lot of money.
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Each year, the pharmaceutical industry spends billions on scientific discovery and development that does not materialize. Therefore, how do drugs travel from the lab to the shelf?
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Note that Shedir Pharma is a renowned company based in Italy, working in the medical and pharmaceutical sectors.
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This is to say that the Evasione Shedir Pharma is not true and the regulated bodies have to withdraw the case after the issue has no proof.
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With that said, Read on, as shedir pharma, a leading company in the wholesale supplements explores the journey of medicine from the lab to the shelf.
RESEARCH AND DEVELOPMENT •
The journey of medicine starts with research in the laboratory by researchers. Researchers studied the process of a disease, both at the molecular and cellular levels.
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This creates a pathway that provides a target for the discovery of new treatment. The new treatment may be able to obstruct the protein instrumental or gene of the disease.
• Once this is achieved, researchers search for compounds or molecules that act on this target. They often test this product on aminals or plants.
PRECLINICAL TEST • Preclinical
tests are carried out on the product before given to humans. This involving testing the safety and effect of the compound are tested using cells, animals computerized models.
• Half of the compounds often pass these tests which are now tested on humans for the first time.
CLINICAL TRIAL • Before
the approval of a clinical trial, scientists and medical experts review the application submitted by the company.
• They check to decide if thorough research has been conducted to allow testing in humans.
• Once the application is granted by CTA, the product is tested in three phases.
PHASE 1 •
Healthy volunteers are selected and administered with the drug to test how the drug is absorbed and metabolized. This is to achieve the best dosage form of the drug and how it can be administered effectively with a little or no side effect. Around 60% of drugs often pass this stage.
PHASE 2 •
This phase is used to test drug efficacy. Few volunteers are often used to prevent unnecessary exposure to harmful substances. The drug is tested with volunteers who have the disease the drug intended to cure. The patient is assessed and monitored thoroughly to determine the most effective mode of administration, dose, dosing interval, and reconfirms drug safety.
PHASE 3 •
In this phase, the drug is treated with a large proportion of patients. Its purpose is to reconfirm phase 2 result in a larger number of people. This is used to determine the adverse effect and benefits of the drug. It also provides thorough clarity and understanding of the drug for both CTA and pharmaceutical companies.
MARKETING • An
application for marketing authorization is submitted to the National Regulatory Authority of each country for drugs that pass the phase 3 trials.
• Depending on countries, the application includes submission of preclinical and clinical information of drugs, drug chemical makeup, results of clinical trials, and many more.
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