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The Concept of Brain Function in Human Development and Learning Process

SITI FARIZA BINTI MOHD ARIFFIN 168598 1


CONTENTS Introduction of brain..............................................................................................................3 How the function of brain can help in studies......................................................................11 Conclusion…………………………………………………………………………………...19 References...............................................................................................................................20

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INTRODUCTION OF BRAIN Brain is the most complex part of the human body. This three-pound organ is the seat of intelligence, interpreter of the senses, initiator of body movement, and controller of behavior. Lying in its bony shell and washed by protective fluid, the brain is the source of all the qualities that define our humanity. Scientists have learned more about the brain in the last 10 years than in all previous centuries because of the accelerating pace of research in neurological and behavioral science and the development of new research techniques. As a result, Congress named the 1990s the Decade of the Brain. At the forefront of research on the brain and other elements of the nervous system is the National Institute of Neurological Disorders and Stroke (NINDS), which conducts and supports scientific studies in the United States and around the world. This fact sheet is a basic introduction to the human brain. It may help you understand how the healthy brain works, how to keep it healthy, and what happens when the brain is diseased or dysfunctional.

The Architecture of the Brain All the parts of the brain work together, but each part has its own special properties. The brain can be divided into three basic units: the forebrain, the midbrain, and the hindbrain. The hindbrain includes the upper part of the spinal cord, the brain stem, and a wrinkled ball of tissue called the cerebellum(1). The hindbrain controls the body’s vital functions such as respiration and heart rate. The cerebellum coordinates movement and is involved in learned rote movements. The uppermost part of the brainstem is the midbrain, which controls some reflex actions and is part of the circuit involved in the control of eye movements and other voluntary movements. The forebrain is the largest and most highly developed part of the human brain which is it consists primarily of the cerebrum(2) and the structures hidden 3


beneath it (see "The Inner Brain"). The cerebrum sits at the topmost part of the brain and is the source of intellectual activities. It holds your memories, allows you to plan, enables you to imagine and think. It allows you to recognize friends, read books, and play games. The cerebrum is split into two halves (hemispheres) by a deep fissure. Despite the split, the two cerebral hemispheres communicate with each other through a thick tract of nerve fibers that lies at the base of this fissure. Although the two hemispheres seem to be mirror images of each other, they are different. For instance, the ability to form words seems to lie primarily in the left hemisphere, while the right hemisphere seems to control many abstract reasoning skills. For some as-yet-unknown reason, nearly all of the signals from the brain to the body and vice-versa cross over on their way to and from the brain. This means that the right cerebral hemisphere primarily controls the left side of the body and the left hemisphere primarily controls the right side. When one side of the brain is damaged, the opposite side of the body is affected. For example, a stroke in the right hemisphere of the brain can leave the left arm and leg paralyzed.

The Forebrain

The Midbrain

The Hindbrain

The Geography of Thought Each cerebral hemisphere can be divided into sections, or lobes, each of which specializes in different functions. To understand each lobe and its specialty we will take a tour of the cerebral hemispheres, starting with the two frontal lobes(3), which lie directly behind the forehead. When you plan a schedule, imagine the future, or use reasoned arguments, these two lobes do much of the work. One of the ways the frontal lobes seem to do these things is by acting as short-term storage sites, allowing one idea to be kept in mind while other ideas are considered. In the rearmost portion of each frontal lobe is a motor area(4), which helps control voluntary movement. A nearby place on the left frontal lobe called Broca’s area(5) allows thoughts to be transformed into words. When we enjoy a good meal, the taste, aroma, and texture of the food, two sections behind the frontal lobes called the parietal lobes(6) are at work. The forward parts of these lobes, just behind the motor areas, are the primary sensory areas(7). These areas receive information about temperature, taste, touch, and movement from the rest of the body. As you look at the words and pictures on this page, two areas at the back of the brain are at work. These lobes, called the occipital lobes(8), process images from the eyes and link that information with images stored in memory. Damage to the occipital lobes can cause blindness. The last lobes on our tour of the cerebral hemispheres are the temporal 4


lobes(9), which lie in front of the visual areas and nest under the parietal and frontal lobes. At the top of each temporal lobe is an area responsible for receiving information from the ears. The underside of each temporal lobe plays a crucial role in forming and retrieving memories, including those associated with music. Other parts of this lobe seem to integrate memories and sensations of taste, sound, sight, and touch.

The Cerebral Cortex Coating the surface of the cerebrum and the cerebellum is a vital layer of tissue the thickness of a stack of two or three dimes. It is called the cortex, from the Latin word for bark. Most of the actual information processing in the brain takes place in the cerebral cortex. When people talk about "gray matter" in the brain they are talking about this thin rind. The

cortex is gray because nerves in this area lack the insulation that makes most other parts of the brain appear to be white. The folds in the brain add to its surface area and therefore increase the amount of gray matter and the quantity of information that can be processed.

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The Inner Brain Deep within the brain, hidden from view, lie structures that are the gatekeepers between the spinal cord and the cerebral hemispheres. These structures not only determine our emotional state, they also modify our perceptions and responses depending on that state, and allow us to initiate movements that you make without thinking about them. The hypothalamus(10), about the size of a pearl, directs a multitude of important functions. It wakes you up in the morning, and gets the adrenaline flowing during a test or job interview. The hypothalamus is also an important emotional center, controlling the molecules that make you feel exhilarated, angry, or unhappy. Near the hypothalamus lies the thalamus(11), a major clearinghouse for information going to and from the spinal cord and the cerebrum. An arching tract of nerve cells leads from the hypothalamus and the thalamus to the hippocampus(12). This tiny nub acts as a memory indexer that sending memories out to the appropriate part of the cerebral hemisphere for long-term storage and retrieving them when necessary. The basal ganglia (not shown) are clusters of nerve cells surrounding the thalamus. They are responsible for initiating and integrating movements. Parkinson’s disease, which results in tremors, rigidity, and a stiff, shuffling walk, is a disease of nerve cells that lead into the basal ganglia.

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Making Connections The brain and the rest of the nervous system are composed of many different types of cells, but the primary functional unit is a cell called the neuron. All sensations, movements, thoughts, memories, and feelings are the result of signals that pass through neurons. Neurons consist of three parts. The cell body(13) contains the nucleus, where most of the molecules that the neuron needs to survive and function are manufactured. Dendrites(14) extend out from the cell body like the branches of a tree and receive messages from other nerve cells. Signals then pass from the dendrites through the cell body and may travel away from the cell body down an axon(15) to another neuron, a muscle cell, or cells in some other organ. The neuron is usually surrounded by many support cells. Some types of cells wrap around the 6


axon to form an insulating sheath(16). This sheath can include a fatty molecule called myelin, which provides insulation for the axon and helps nerve signals travel faster and farther. Axons may be very short, such as those that carry signals from one cell in the cortex to another cell less than a hair’s width away. Or axons may be very long, such as those that carry messages from the brain all the way down the spinal cord.

Scientists have learned a great deal about neurons by studying the synapse which is the place where a signal passes from the neuron to another cell. When the signal reaches the end of the axon it stimulates the release of tiny sacs(17). These sacs release chemicals known as neurotransmitters(18) into the synapse(19). The neurotransmitters cross the synapse and attach to receptors(20) on the neighboring cell. These receptors can change the properties of the receiving cell. If the receiving cell is also a neuron, the signal can continue the transmission to the next cell.

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Some Key Neurotransmitters at Work Acetylcholine is called an excitatory neurotransmitter because it generally makes cells more excitable. It governs muscle contractions and causes glands to secrete hormones. Alzheimer’s disease, which initially affects memory formation, is associated with a shortage of acetylcholine. GABA (gamma-aminobutyric acid) is called an inhibitory neurotransmitter because it tends to make cells less excitable. It helps control muscle activity and is an important part of the visual system. Drugs that increase GABA levels in the brain are used to treat epileptic seizures and tremors in patients with Huntington’s disease. Serotonin is a neurotransmitter that constricts blood vessels and brings on sleep. It is also involved in temperature regulation. Dopamine is an inhibitory neurotransmitter involved in mood and the control of complex movements. The loss of dopamine activity in some portions of the brain leads to the muscular rigidity of Parkinson’s disease. Many medications used to treat behavioral disorders work by modifying the action of dopamine in the brain.

Neurological Disorders When the brain is healthy it functions quickly and automatically. But when problems occur, the results can be devastating. Some 50 million people in this country which is one in five are suffer from damage to the nervous system. The NINDS supports research on more than 600 neurological diseases. Some of the major types of disorders include: neurogenetic diseases (such as Huntington’s disease and muscular dystrophy), developmental disorders (such as cerebral palsy), degenerative diseases of adult life (such as Parkinson’s disease and Alzheimer’s disease), metabolic diseases (such as Gaucher’s disease), cerebrovascular diseases (such as stroke and vascular dementia), trauma (such as spinal cord and head injury), convulsive disorders (such as epilepsy), infectious diseases (such as AIDS dementia), and brain tumors.

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Memory is a complicated process that’s made up of a few different brain activities. Here’s a simplified version to help us understand how the process takes place: 1. Creating a memory Our brain sends signals in a particular pattern associated with the event we’re experiencing and creates connections between our neurons, called synapses.

2. Consolidating the memory If we didn’t do anything further, that memory would fall right out of our heads again. Consolidation is the process of committing it to long-term memory so we can recall it later. A lot of this process happens while we’re sleeping, as our brains recreate that same pattern of brain activity to strengthen the synapses we created earlier. 3. Recalling the memory This is what most of us think of when we talk about memory, or especially memory loss. Recalling the memory is easier if it’s been strengthened over time, and each time we do so, we run through that same pattern of brain activity again, making it a little stronger. Memory loss is a normal part of aging, but that doesn’t mean we can’t take action to slow it down a little. Let’s take a look at some of the ways research has found to keep our memories around as long as possible.

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HOW THE FUNCTION OF BRAIN CAN HELP IN STUDIES

1. Exercise As I write in the May 2014 Harvard Health Letter, exercise helps memory and thinking through both direct and indirect means. The benefits of exercise come directly from its ability to reduce insulin resistance, reduce inflammation, and stimulate the release of growth factors which is chemicals in the brain that affect the health of brain cells, the growth of new blood vessels in the brain, and even the abundance and survival of new brain cells. Indirectly, exercise improves mood and sleep, and reduces stress and anxiety. Problems in these areas frequently cause or contribute to cognitive impairment. Many studies have suggested that the parts of the brain that control thinking and memory (the prefrontal cortex and medial temporal cortex) have greater volume in people who exercise versus people who don’t. Exercise encourages your brain to work at optimum capacity by causing nerve cells to multiply, strengthening their interconnections and protecting them from damage. During exercise nerve cells release proteins known as neurotrophic factors. One in particular, called brain-derived neurotrophic factor (BDNF), triggers numerous other chemicals that promote neural health, and directly benefits cognitive functions, including learning. A 2010 study on primates published in Neuroscience also revealed that regular exercise not only improved blood flow to the brain, but also helped the monkeys learn new tasks twice as quickly as nonexercising monkeys, a benefit the researchers believe would hold true for people as well. Still more research has shown that exercise boosts mitochondria, organelles that produce energy within every cell of your body, which suggests exercise may help your brain work faster and more efficiently. For example, It’s been proven that exercise can boost your memory and brain power. Research conducted by Dr. Chuck Hillman of the University of Illinois provides evidence that about 20 minutes exercise before an exam can improve performance.

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2. Sleep Sleep is not only essential for regenerating your physical body, but it is imperative for reaching new mental insights and being able to see new creative solutions to old problems. Sleep removes the blinders and helps "reset" your brain to look at problems from a different perspective, which is crucial to creativity. Research from Harvard indicates that people are 33 percent more likely to infer connections among distantly related ideas after sleeping, but few realize that their performance has actually improved. Sleep is also known to enhance your memories and help you "practice" and improve your performance of challenging skills. In fact, a single night of sleeping only four to six hours can impact your ability to think clearly the next day. The process of growth, known as plasticity, is believed to underlie the brain's capacity to control behavior, including learning and memory. Plasticity occurs when neurons are stimulated by events, or information, from the environment. However, sleep and sleep loss modify the expression of several genes and gene products that may be important for synaptic plasticity. Furthermore, certain forms of long-term potentiation, a neural process associated with the laying down of learning and memory, can be elicited in sleep, suggesting synaptic connections are strengthened while you slumber. As you might suspect, this holds true for infants too, and research shows that naps can give a boost to babies' brainpower. Specifically, infants who slept in between learning and testing sessions had a better ability to recognize patterns in new information, which signals an important change in memory that plays an essential role in cognitive development. Even among adults, a mid-day nap was found to dramatically boost and restore brainpower. In one study, participants memorized illustrated cards to test their memory strength. After memorizing a set of cards, they had a 40-minute break wherein one group napped, and the other stayed awake. After the break, both groups were tested on their memory of the cards, the group who had napped performed better: Much to the surprise of the researchers, the sleep group performed significantly better, retaining on average 85 percent of the patterns, compared to 60 percent for those who had remained awake.

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Apparently, napping actually helps our brain to solidify memories:

Research indicates that when memory is first recorded in the brain—in the hippocampus, to be specific—it’s still “fragile” and easily forgotten, especially if the brain is asked to memorize more things. Napping, it seems, pushes memories to the neocortex, the brain’s “more permanent storage,” preventing them from being “overwritten.” Not only is sleep after learning a critical part of the memory creation process, but sleep before learning something new is important as well. Research has found that sleep deprivation can affect our ability to commit new things to memory and consolidate any new memories we create. Other than that, make sure to get adequate rest the nights leading up to your exams. When you sleep, your brain assimilates the information you have learned when studying.

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3. Meditate to improve your working memory Working memory, which is a bit like the brain’s notepad, is where new information is held temporarily. When you learn someone’s name or hear the address of a place you’re going to, you hang on to those details in working memory until you’re done with them. If they’re not useful anymore, you let go of them entirely. If they are, you commit them to long-term memory where they can be strengthened and recalled later. Working memory is something we use every day, and it makes our lives a lot easier when it’s stronger. For most adults, the maximum we can hold in our working memory is about seven items, but if you’re not quite using your working memory to its max capacity, meditation is one thing you can try to strengthen it. Research has shown that participants with no experience in mindfulness meditation can improve their memory recall in just eight weeks. Meditation, with its power to help us concentrate, has also been shown to improve improve standardized test scores and working memory abilities after just two weeks. Why does meditation benefit memory? It’s somewhat counterintuitive. During meditation, our brains stop processing information as actively as they normally would. In the image below you can see how the beta waves (shown in bright colors on the left), which indicate that our brains are processing information, are dramatically reduced during meditation (on the right).

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4. Listen to Music It's long been theorized that listening to music may boost your brainpower; you've probably heard of this with the "Mozart Effect," which suggests listening to classical music can make you smarter. Indeed, research has shown that listening to music while exercising boosted cognitive levels and verbal fluency skills in people diagnosed with coronary artery disease (coronary artery disease has been linked to a decline in cognitive abilities). In this study, signs of improvement in the verbal fluency areas more than doubled after listening to music compared to that of the non-music session. Listening to music has also been associated with enhanced cognitive functioning and improved mental focus among healthy adults, so take advantage of this simple pleasure whenever you can.

5. Challenge Your Mind One of the simplest methods to boost your brain function is to keep on learning. The size and structure of neurons and the connections between them actually change as you learn. This can take on many forms above and beyond book learning to include activities like traveling, learning to play a musical instrument or speak a foreign language, or participating in social and community activities. Another important method? Brain aerobics. As with learning, challenging your brain with mind-training exercises can keep your brain fit as you age. This can be something as simple as thinking of famous people whose first names begin with the letter A, doing crossword puzzles or playing board games that get you thinking. Research has even shown that surfing the Web activates regions in your brain related to decision-making and complex reasoning. So unlike passively watching TV, using the Internet is an engaging task that may actually help to improve your brainpower.

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6. Create Mental Associations The ability to make connections is not only an easier way to remember information, but it’s the fuel of creativity and intelligence. Steve Jobs famously said “Creativity is just connecting things. When you ask creative people how they did something, they feel a little guilty because they didn’t really do it, they just saw something”. Mind Maps are an easy way to connect ideas by creating a visual overview of different connections.

7. Draw Diagrams Drawing diagrams will help you to visualise information which would be hard to describe. This creates a visual memory in your mind which can be recalled in an exam.

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8. Take Regular Study Breaks When your brain is working, you need to take regular study breaks to help your brain absorb more information but also to keep you motivated and focused when you are working. Take a short break after 45-50 minutes study as your focus and concentration will become impaired after this period, anything new after 1 hour 30 minutes does not get assimilated.

9. Animal-Based Omega-3 Fats Docosahexaenoic acid, or DHA, an omega-3 fat, is an essential structural component of both your brain and retina. Approximately 60 percent of your brain is composed of fats which is 25 percent of it is DHA. DHA is also an essential structural ingredient of breast milk, which is believed to be a major reason why breastfed babies consistently score higher on IQ tests than formula-fed babies. Omega-3 fats such as DHA are considered essential because your body cannot produce it, and must get it from your daily diet. DHA-rich foods include fish, liver, and brain which all of it are no longer consumed in great amounts by most Americans. DHA is found in high levels in your neurons which is the cells of your central nervous system, where it provides structural support. When your omega-3 intake is inadequate, your nerve cells become stiff and more prone to inflammation as the missing omega-3 fats are substituted with cholesterol and omega-6 instead. Once your nerve cells become rigid and 16


inflamed, proper neurotransmission from cell to cell and within cells become compromised. The influence of omega-3 fat on physical and mental health has been the subject of intense research over the last four decades, and there's compelling evidence that animal-based omega3 fats can help reduce the symptoms of a variety of psychiatric illnesses and degenerative brain disorders. For example, low DHA levels have been linked to memory loss and Alzheimer's disease. 10. Coconut Oil One of the primary fuels your brain needs is glucose, which is converted into energy. Your brain actually manufactures its own insulin to convert glucose in your bloodstream into the food it needs to survive. If your brain's production of insulin decreases, your brain literally begins to starve, as it's deprived of the glucose-converted energy it needs to function normally. This is what happens to Alzheimer's patients which the portions of their brain start to atrophy, or starve, leading to impaired functioning and eventual loss of memory, speech, movement and personality. In effect, your brain can begin to atrophy from starvation if it becomes insulin resistant and loses its ability to convert glucose into energy. Fortunately, your brain is able to run on more than one type of energy supply, and this is where coconut oil enters the picture.

11. Vitamin D Activated vitamin D receptors increase nerve growth in your brain, and researchers have also located metabolic pathways for vitamin D in the hippocampus and cerebellum of the brain, areas that are involved in planning, processing of information, and the formation of new memories. The National Institutes of Mental Health recently concluded that it is vital that the mother get enough vitamin D while pregnant in order for the baby's brain to develop properly. The child must also get enough vitamin D after birth for "normal" brain functioning. In older adults, too, research has shown that low vitamin D levels are associated with poorer brain function, and increasing levels may help keep older adults mentally fit. Appropriate sun exposure would take care of these issues, as the sun is irreplaceable when it comes to the body's ability to produce adequate amounts of vitamin D. Appropriate sun exposure is all it takes to keep your levels where they need to be for healthy brain function.

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12. Vitamin B12 Vitamin B12, or rather a lack thereof, has been called the "canary in the coalmine" for your future brain health, and recent research has bolstered the importance of this vitamin in keeping your mind sharp as you age. According to the latest research, people with high levels of markers for vitamin B12 deficiency were more likely to score lower on cognitive tests, as well as have a smaller total brain volume, which suggests a lack of the vitamin may contribute to brain shrinkage. Mental fogginess and problems with memory are two of the top warning signs that you have vitamin B12 deficiency, and this is indicative of its importance for your brain health. In addition, a Finnish study found that people who consume foods rich in B12 may reduce their risk of Alzheimer's in their later years. For each unit increase in the marker of vitamin B12 (holotranscobalamin) the risk of developing Alzheimer's was reduced by 2 percent. Research also shows that supplementing with B vitamins, including B12, helps to slow brain atrophy in elderly people with mild cognitive impairment (brain atrophy is a wellestablished characteristic of Alzheimer's disease). B12 is available in its natural form only in animal food sources. These include seafood, beef, chicken, pork, milk, and eggs.

13. Eat berries for better long-term memory Another diet-related effect on memory is the mounting research that eating berries can help to stave off memory decline. A study from the University of Reading and the Peninsula Medical School found that supplementing a normal diet with blueberries for twelve weeks improved performance on spatial working memory tasks. The effects started just three weeks in and continued for the length of the study. A long-term berry study that tested the memory of female nurses who were over 70 years old found that those who had regularly eaten at least two servings of strawberries or blueberries each week had a moderate reduction in memory decline. More research is needed in this area, but science is getting closer to understanding how berries might affect our brains. In particular, blueberries are known for being high in flavanoids, which appear to strengthen existing connections in the brain. That could explain why they’re beneficial for long-term memory.

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CONCLUSION As a conclusion, brain is the most complex part of the human body that have a lot of function for human. As we discussed above, there are so many function of brain that can help in studies. Brain consists of many parts such as forebrain, midbrain and hindbrain. It also consists of frontal lobes, motor area, broca’s area, parietal lobes, primary sensory area, occipital lobes and temporal lobes. In inner brain, it consists of hypothalamus, thalamus and hippocampus. Each part of brain has its own function that can help in studies. There are several activities that can help brain functioning well in studies such as exercise, sleep, meditate, listen to music, challenge mind, draw diagram and others like what we already discussed above. So, we should have some effort to take care of our brain so that it can functioning well and help us in a lot of things. If our brain cannot function, there are no things that we can do in our life.

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