Calcium Homeostasis

CA L CI U M HO M E O S T A S I S

B A C K G R O U ND I N F O R M A T I O N

• Antiresorptive agents (slow rate of bone loss): o Bisphosphates o Hormone replacement therapy o Selective Estrogen Receptor Modulators (SERM) o RANKL anatoginists

• Bone anabolic agents (increase bone formation): o Parathyroid hormone analogues o Vitamin D replacement o Calcium salts • Management of hypo/hypercalcemia: o Targets correction of the cause - If due to dysfunction of endocrine system, endocrinologist is involved; if due to certain treatments or medications, they are altered or removed if possible.