Clinical Trial Participants Needed

Hundreds of clinical trials are conducted throughout Greenville Health System on a variety of drug therapies, surgical devices and other treatments in all areas of medicine.

Cancer survivors for registry

GHS Cancer Institute’s Cancer Survivor Registry is a database of demographics, contact information, and tumor and treatment information. Survivors can receive helpful information about moving forward. Contact Matt, (864) 455-5119 or molinger2@ghs.org.

Survivors of breast cancer as advisers

The Breast Cancer Patient Engagement Studio is looking for women who have experienced breast cancer or their family members to help review projects designed to provide better care for patients. Patient opinions are needed! Participation involves meeting as an adviser (not a research participant) with a group of similar patients, researchers and clinicians to review projects as they are proposed. If interested, a patient application is available at hsc.ghs.org/ pes/application. You also may call (864) 455-8894 or email the Studio at PEStudio@ghs.org. If selected, you will receive compensation for taking part on the patient advisory board.

Patients beginning cancer treatment

This study looks at how body composition changes over the course of cancer treatment. Body composition will be evaluated using the SOZO device, which can identify a participant’s fluid status, fat mass, fat-free mass, metabolic report, skeletal muscle mass and hydration index. The study will last the duration of the participant’s cancer treatment. Participants will receive $100. Contact Armand, (864) 455-6251 or adesollar@ghs.org.

Survivors of lung cancer having anxiety

The purpose of the Reducing Lung Cancer Survivors’ Anxiety (RELAX) research study is to compare the effects of device-guided breathing on anxiety and shortness of breath in survivors of lung cancer. This study is open to survivors of early-stage lung cancer who have completed treatment and are experiencing anxiety. The study will involve using a breathing device daily for 12 weeks and filling out questionnaires. Contact Claudette, (864) 522-4263 or cphinney@ghs.org.

Survivors of cancer with sedentary behavior

The purpose of the study is to determine the effectiveness of listening to audiobooks in increasing physical activity among survivors of cancer. Walking Inspires Seniors (WISE) Audiobook Study will track the number of steps taken by participants over the course of 12 weeks using a Fitbit. Participants will be randomized into either the audiobook group or the control group. This study is open to patients who were referred to the Moving On program, part of the Center for Integrative Oncology and Survivorship, and were unable to attend. You may be eligible to participate if you are 65 years old or older, able to walk unassisted, able to hear audiobooks and have access to a library. Contact Ginny, (864) 455-5943 or vsimmons@ghs.org.

Survivors of breast or gynecologic cancer

Long-term effects for some survivors can include unwanted changes in sexual health. The purpose of this study is to determine if a medication called bupropion, already approved for several uses, can help women who have decreased sexual desire after completing cancer treatment. The study is open to post-menopausal women who have completed treatment for breast or GYN cancer at least six months ago. Study participants still can be on Herceptin or some types of hormonal therapies. The study lasts 10 weeks and will compare bupropion with a placebo. The medication is free. Call Claudette, (864) 522-4263.

Women having a cesarean

The purpose of this study is to determine if a drug called tranexamic acid (TXA) will prevent severe bleeding (hemorrhage) after a cesarean delivery. Some bleeding occurs when a woman has a cesarean delivery. Occasionally (in fewer than five of every 100 births), severe bleeding can place the mother’s health at risk. When too much bleeding occurs, women are given medicines and blood transfusions or possibly may need another surgery.

TXA routinely is used to lessen the chance of bleeding after major operations (such as heart surgery) by making the blood clot sooner. It is not routinely used for cesarean sections. Women enrolled will be randomized (like flipping a coin) to receive either 1 gm of TXA or saline solution (no drug) after delivery. All other care and treatment are routine for a cesarean delivery. If you are delivering at Greenville Memorial Hospital, you may be approached about participation. Call Allison or Anthony, (864) 982-4894.

Adults with type 2 diabetes or nonalcoholic fatty liver disease (NAFLD)

The purpose of these studies is to evaluate the effect of novel medications for the advanced form of NAFLD called NASH/fibrosis. You may have NASH/ fibrosis if you have hypertension, diabetes, elevated lipids or a previous diagnosis of fatty liver. For a limited time, we are offering a free FibroScan, a non-invasive, painless ultrasound exam that can estimate if you have any fibrosis, a precursor to cirrhosis of the liver. Studies last one to seven years. Study drugs, lab tests, X-rays, etc., are free. Participants receive a small stipend. Contact Donna, (864) 455-2846 or dwest3@ghs.org or Alicia, (864) 455-2043 or Ajones1df23@ghs.org.