Doctors Won’t Prescribe Hormone Therapy to Woman Over 60

DEAR DR. ROACH: In a recently published column, you stated, “As always, the decision belongs to the patient,” while addressing a concern about the benefits and risks of stopping a statin drug. Oh, really? Then, why is it that, once I turned 60, not a single doctor will prescribe hormone replacement therapy (HRT) to stop my debilitating post-menopausal symptoms? After suffering from menopausal symptoms starting at age 42, I was finally prescribed HRT at age 57. What relief I felt, as it was the only remedy to alleviate my hot flashes, weight gain, lack of sleep and vaginal dryness.

Once I hit 60, I was ordered to stop HRT, and no one since will prescribe it for me now. I am 66, suffer from hot flashes daily and have my sleep interrupted at least five times a night with terrible night sweats. I have tried just about every over-the-counter offering with zero effectiveness.

I will gladly trade the greater risk of heart attack and stroke, and the possible shorter life span, for relief from symptoms that affect my daily quality of life. Clearly, the choice is not mine, because if I had a choice, I would ask for continued prescriptions of HRT to give me relief. Why don’t I have that choice as a patient? -- R.M.T.

ANSWER: A patient always has the right to refuse a treatment recommended from a physician. However, the physician has the obligation to consider the risks and benefits of a treatment, and is not obliged to prescribe a treatment that they do not think is appropriate.

If a patient asks me for a treatment that has been shown to be ineffective and has the potential for serious adverse effects, I don’t prescribe it, but will work with the patient to find alternative treatments. For example, some nonhormonal prescription treatments are moderately effective for hot flashes and sleep disturbance, and topical estrogen is very effective for vaginal dryness.

However, the case of HRT for symptoms of menopause is more complicated, because estrogen is the most effective treatment we have for menopausal symptoms, particularly for hot flashes. There are risks to HRT, but the benefits for some women are so great that they are willing to accept some risks.

You mentioned the risk of heart disease and stroke. A landmark study called the Women’s Health Initiative helped to define and quantify those (and other) risks. Its effect has been to dramatically reduce the prescribing of menopausal hormone therapy, but the results should not be interpreted to mean that hormone treatment is always inappropriate, even in women who are in their mid-60s, where risks are higher.

Moreover, a woman’s entire health status should be considered when deciding whether to prescribe hormone treatments. In women with a history of an estrogen-dependent tumor (like many breast cancers), a history of a blood clot or a stroke, or a few other issues, the harm almost certainly outweighs the benefits. Otherwise, a wise clinician looks at the patient’s risk for heart disease, blood clots and similar conditions. Women at a very high risk for heart disease should probably avoid estrogen. Using lower-dose estrogen by patch (rather than pills) is wise for women at moderate risk, such as those who are in their 60s.

Physicians do not want to prescribe medications that will harm their patients, and most have stopped prescribing menopausal hormone therapy entirely for women, to prevent disease. However, it still has a role in treating symptoms. I recommend you seek out an expert in treatment of menopausal treatments and have a frank discussion about your willingness to assume risk in order to have a better quality of life.

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Dr. Roach regrets that he is unable to answer individual questions, but will incorporate them in the column whenever possible. Readers may email questions to ToYourGoodHealth@med.cornell.edu.

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How To

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Request For Proposal

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