4 Renal & Urology News
SPRING 2022
www.renalandurologynews.com
News in Brief
Please visit us at www.renalandurologynews.com for the latest news updates from the fields of urology and nephrology
Short Takes FDA Approves Product to Aid Renal Imaging The FDA has approved NephroScan™
replacement therapy from 2781 US counties. All-cause mortality rates standard-
(kit for the preparation of technetium
ized by age among patients with
Tc 99m succimer injection) for use
ESKD ranged from 45 to 1022 per
as an aid in the scintigraphic evalua-
1000 person-years across counties,
tion of renal parenchymal disorders in
Kylie K. Snow, MPH, of Rollins School
adults and pediatric patients including
of Public Health, Emory University,
term neonates.
Atlanta, Georgia, and colleagues
NephroScan is a sterile, single-dose
reported in Kidney360.
kit for the preparation of technetium Tc Tc 99m succimer binds to the cortical
Frailty May Up Vascular Access Thrombosis Risk
region of kidneys, and in conjunction
Frail patients on hemodialysis (HD) are
with gamma scintigraphy or single pho-
at elevated risk for vascular access
ton emission computed tomography, is
(VA) thrombosis, according a study
used to image the renal cortices.
published in the American Journal of
99m succimer injection. Technetium
Kidney Diseases.
ESKD Patient Death Rates Vary By County
centers in Taiwan, frail patients had a
In the United States, 18.9% of the
significant 2.3-fold higher risk for VA
variation in death rates among pa-
thrombosis compared with robust pa-
tients with end-stage kidney disease
tients, a team led by Chih-Cheng Wu,
(ESKD) is attributable to county-level
MD, of National Taiwan University in
factors such as demographics and
Taipei, reported. The investigators as-
health care spending, according to a
sessed frailty using the Fried scoring
recent study.
method, assigning 1 point for each of
Using 2010-2018 data from the
In a study of 761 patients at 9 HD
the following if present: weight loss,
US Renal Data System, investigators
exhaustion, low activity level, low grip
identified 1,515,986 adults (aged
strength, and slow walking speed. A
18-84 years) who initiated renal
score of 3 to 5 indicated frailty.
Racial Divide in CPR Use In a study of patients experiencing cardiac arrest at dialysis centers, Black patients had significant 57% lower odds of receiving CPR from staff members compared with White patients, according to a recent study. Here are the percentages of patients, by race, who did not receive CPR.
BLACK: 15%
WHITE: 9%
OTHER: 12%
Source: Pun PH, et al. Facility-level factors and racial disparities in cardiopulmonary resuscitation within US dialysis clinics. Kidney360. Published online March 11, 2022. doi:10.34067/KID.0008092021
Hyperuricemia May Be Linked to SHPT in Patients With CKD H
yperuricemia may contribute to development of secondary hyperparathyroidism (SHPT) in patients with chronic kidney disease (CKD), possibly independent of renal function, investigators suggest. Among 922 patients with stages 3 or higher CKD not on dialysis, SHPT and hyperuricemia occurred in 70% and 62.4%, respectively. The group with vs without SHPT had significantly higher mean levels of serum uric acid (7.2 vs 6.6 mg/ dL) and a significantly higher prevalance of hyperuricemia (66% vs 33%), Rosilene M. Elias, MD, and colleagues from Hospital das Clinicas HCFMUSP in São Paulo, Brazil, reported in International Urology and Nephrology. In multivariable analyses, hyperuricemia remained independently associated with SHPT.
Study: Same-Day Discharge After RARP Is Safe, Feasible S
ame-day discharge (SDD) following robot-assisted radical prostatectomy (RARP) is feasible and safe, with complication and readmission rates comparable to those of inpatient RARP, data reported at the 2022 Genitourinary Cancers Symposium suggest. The findings are from a systematic review and meta-analysis of data from 14 studies (8 prospective and 6 retrospective cohort studies) with a pooled population of 3795 patients, including 2348 (61.9%) who underwent inpatient RARPs and 1447 (38.1%) who underwent SDD RARPs. Compared with the inpatient RARP group, patients who had SDD RARPs did not differ significantly with respect to grade 3 or higher Clavien-Dindo complications, 90-day readmission rates, or unscheduled emergency department visits, Michael Uy, MD, of McMaster University in Hamilton, Ontario, Canada, and colleagues reported. Cost savings per patient ranged from $367 to $2109 in US dollars. Overall satisfaction rates were high (87.5%-100%).
Patients With Cancer Are At Higher Risk for Kidney Failure P
atients with cancer have a higher risk for kidney failure requiring replacement therapy (KFRT), and that risk differs by cancer type, a new study finds. Using the Korean National Health Insurance Service database, investigators examined KFRT risk among 824,365 Korean patients with cancer compared with 1,648,730 patients without cancer matched by age, sex, estimated glomerular filtration rate (eGFR), diabetes status, and hypertension status. KFRT was required for 1.07 patients with cancer compared with 0.51 patients without cancer per 1000 person-years, Soo Wan Kim, MD, PhD, Chonnam National University Medical School, Korea, and colleagues reported in the American Journal of Kidney Diseases. Cancer was significantly associated with a 2.3-fold increased risk for KFRT, in a fully adjusted model. Among patients with chronic kidney disease (CKD), those with vs without cancer had a significant 1.4fold increased risk for KFRT. Among patients with proteinuria, cancer was associated with a significant 1.3-fold increased risk for KFRT.
