This late November 2019 issue #49 of High! Canada Magazine features information on Cannabis Substitution and information from the recent BC Centre on Substance Use - Cannabis Science Symposium on Cannabis and harm reduction: What we know and what we need to learn. This issue also looks at current business trends with Pure Sunfarms and Nameste Technologies, N2 Packaging taking a lead in sustainability, O'Cannabiz Keynote Speakers announced, news from Allied Corp., Aphria Inc. and Freedom Cannabis Inc, new research and information on cannabinoids, and much more...