15:45-16:45 | Orion Hall (5F) Friday Poster Session | AGen2023

68438 | Associations Between Sarcopenia, Osteopenia, and Obesity in Healthy Korean Adults by Opportunistic Body Composition Evaluation Using FDG PET/CT

So Won Oh, Seoul National University Boramae Medical Center, South Korea

Chang-Myung Oh, Gwangju Institute of Science and Technology, South Korea

Yong Hwy Kim, Seoul National University, South Korea

Jae Kyung Lee, Seoul National University Boramae Medical Center, South Korea

Jee Won Chai, Seoul National University Boramae Medical Center, South Korea

The present study evaluated opportunistic body composition in healthy Korean adults who performed FDG-PET/CT for cancer screening. FDG-PET/ CT, dual-energy X-ray absorptiometry (DXA), bioelectrical impedance analysis (BIA), clinical history, and laboratory data of healthy Korean adults (M:F= 136:131, 60.76 ± 9.95y) who performed health screening program at our institute from 2017 to 2022 were analyzed. The distribution and quantification of abdominal visceral (VAT) and subcutaneous (SAT) fat tissues, crossed skeletal muscle area (CSMA) were evaluated, and bone mineral density (BMD), fat contents of liver and muscle were measured as Hounsfield unit (HU) level using non-enhanced CT images of FDG-PET/ CT. Metabolic activity of all these tissues was measured on PET images of FDG-PET/CT. BMD and HU of the muscle steadily decreased with age. Both CSMA and BMD decreased with age, and they well correlated each other. CSMA was inversely correlated with the amount of SAT and VAT. Not SAT but VAT significantly increased with age. Fat content of liver was correlated with age and inversely correlated with CSMA only in women. In comparisons of normal and fatty liver groups, HU of the muscle was significant lower in the fatty liver group, but metabolism of the muscle was not different. Amount of both SAT and VAT were significantly larger, while glucose metabolism of both SAT and VAT were lower in the fatty liver group than in the normal group. Sarcopenic individuals tend to be osteopenic and obese, and present more fatty content in the liver and muscle.

68442 | Apathy Prevalence Among Geriatric Inpatients: Significance for Healthcare Interventions

Krzysztof Wilczynski, Silesian Medical University in Katowice, Poland

Purpose: We examined the prevalence of apathy in the context of neuropsychiatric symptoms in elderly people with dementia, mild cognitive impairment, and no cognitive impairment. The significance of apathy is considered in relation to active patient participation in health maintenance interventions and health maintenance technologies such as remote patient monitoring and state of the art well-being systems.

Methods: Cross-sectional study of 236 consecutive patients out of 650 admitted to an inpatient geriatric ward with a comprehensive geriatric assessment was performed and where a caregiver completed a neuropsychiatric inventory that includes 12 domains: delusions, hallucinations, agitation/aggression, dysphoria/depression, anxiety, euphoria/elation, apathy/indifference, disinhibition, irritability/lability, aberrant motor, nighttime disturbances and appetite/eating disturbances. Results: Average patient age was 80.7±6.6 years (x +/- SD) within a range of 63 to 99 years, 64.1% women. Apathy was the most frequently reported NPS in patients with dementia and mild cognitive impairment at 69.4% and 61.5%, respectively. In patients without cognitive impairment, the most frequent NPS were appetite/eating disturbances (44.9%), depression (41.5%), and apathy (40%).

Conclusion: While apathy and other neuropsychiatric symptoms among patients with dementia are common, our study shows that these symptoms are also common among patients admitted to a geriatric ward with MCI and no cognitive impairment. Apathy among patients with mild cognitive impairment is significant as these persons are especially susceptible to decline in functional capacity and particularly benefit from early interventions. Apathy should be addressed by clinicians and technology innovators to increase success rates with their healthcare solutions.

68572 | Increasing Connect Care Problem List Utilization Amongst Geriatric Physicians Frances Carr, University of Alberta, Canada

Before converting to a new electronic medical system (Connect Care), Problem Lists (PL) were routinely used by all Geriatric physicians. However, there has been minimal use of its PL navigator. This study aimed for 80% of patients admitted to Geriatrics (Acute Care of the Elderly (ACE) unit) or seen in consultation (Geriatric Assessment Team (GAT)) at the University of Alberta Hospital should have their PL reviewed at all transitions of care (ACE unit) or with initial consultation (GAT). The study was conducted from March to November 2022. Initial physician feedback revealed a variety of reasons for poor PL navigator uptake which formed the basis for the intervention, which was a formal education session for physicians which addressed these reasons, presented during a divisional meeting. Physician feedback was also collected post-intervention. One education session was held, attended by all physicians. The average duration for reviewing the problem list was 7.8 mins. Run charts revealed data shifts towards increased PL review at patient admission and PL incorporation into ACE notes, but decreased at transfers of care and with GAT consults. There was a trend towards increased problem duplication. The intervention was positively received, but led to minimal changes in behavior, and a trend towards increased problem duplication. Shifts were most noticeable for ACE patients, suggestive of this being the best target for further intervention. Although the study did not meet its aim, there was evidence of possible changes in behavior, and further exploration of existing barriers is required.

68617 | Consumption of Fruit and Vegetable in Midlife and Risk of Depressive Symptoms in Late Life: The Singapore Chinese Health Study

Huiqi Li, National University of Singapore, Singapore

Woon Puay Koh, National University of Singapore, Singapore

Yiqiang Chua, National Univeristy of Singapore, Singapore

Objective: Epidemiological evidence between consumption of fruit and vegetable and depressive symptoms in late life is limited and inconsistent, especially in Asian populations. We examined this association in a prospective Asian cohort. Methods: We used data from 16,571 participants of the Singapore Chinese Health Study. The consumption of fruits and vegetables was assessed using a validated 165-item food-frequency questionnaire at baseline (1993-1998), when participants were aged 43-74 years (mean age 53.0 years). Fruits were further classified according to climate of growth (temperate, subtropical, and tropical), or glycemic index value (low, moderate, and high). After a mean follow-up of 20 years, depressive symptoms were evaluated using Geriatric Depression Scale during the third follow-up interviews (2014-2016), when participants were aged 61-96 years (mean age 73.2 years). Multivariable logistic regression models were used to calculate odds ratio (OR) and 95% confidence interval (CI). Results: Depressive symptoms were identified among 4372 participants. Consumption of fruits, but not vegetables, was inversely associated with depressive symptoms in a dose-response manner: comparing extreme quartiles, the OR (95% CI) of depressive symptoms was 0.74 (0.66-0.82; P-trend <0.001) for fruits and 0.95 (0.85-1.07; P-trend =0.49) for vegetables consumption. The significantly inverse associations were observed in all subgroups of fruits by glycemic index values. However, in grouping by climate, consumption of subtropical and tropical fruit, but not of temperate fruit, was associated with lower risk of depressive symptoms. Conclusions: Higher midlife consumption of fruits, but not vegetables, was associated with a significantly lower risk of depressive symptoms in late life.