Welcome To the second edition of 2021

Testimonials Professionals’ comment on IAS 02 Welcome To the second edition of 2021 03 Forefront Recent stories in the news 04 The science of aging interventions Professor Rattan explains hormesis 14 Nutrition in cancer prevention & therapy Dr. Marios Kyriazis documents what is useful 20 NAD for longer lifespans Discover the work of Dr. David Sinclair 26 Natural antivirals How mushroom extracts and BHT help 32 Spotlights A few details about special products 38 Media Page Introducing our recommended videos 48 Antiaging-Systems.com Where to find what you need 50

Declaration: The IAS Aging Matters™ magazine is intended for IAS private club members (and therefore is not intended for the public). It focuses on the latest international nutritional, hormonal and drug therapies to help combat the signs of aging. These signs include the physical, mental, and internal changes consisting of the diseases and disorders such as cancer, arthritis, and senile dementias etc. However, the focus is upon the prevention of such aging diseases and disorders for the ‘healthy-aging’ individual. Copyright 2021: All copyrights are acknowledged. Whilst every effort has been made to ensure accuracy, no responsibility can be accepted for illustrations, photographs, artwork, or advertising materials while in transmission or with the publisher or their agents. Disclaimer: All educational information is offered strictly under IAS terms and conditions. This information does not replace the advice of your physician and restrictions may apply in some countries. The opinions expressed by the writers may not be those of IAS, nor the magazine. Terms and conditions are subject to change without notice.

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Your comments are welcome at: editor@aging-matters.com As we head for the middle of 2021, we look to an issue that covers a wide range of topics, all related to health, well-being, and longevity. Firstly, we are honored to have Professor Suresh Rattan from Denmark, (a very prominent individual in the field of biogerontology), tell us about hormesis. This is essentially mild stress, and it can be beneficial for our health, perhaps the most obvious example is exercise. But Professor Rattan also talks about agents that are hormetins, in other words they are agents that can benefit via the pathway of hormesis. Dr. Marios Kyriazis follows this by describing nutrition that has shown benefit in the prevention and in various therapies for different cancer states. Dr. Kyriazis expands on those which also have hormetic effects, and hence we can see the relation between agents that benefit both cancer and longevity. Many people have become aware of the research of Dr. David Sinclair. Some of you may have read his best-selling book called ‘Lifespan.’’ It basically introduces and details the ability to enhance our internal NAD+ levels, and what that can mean to help us to equivocate our healthspan to our lifespan. We explore the NAD boosters and other ancillary agents that have been shown to naturally increase NAD. Our last article is focused on natural antivirals, particularly those found in mushroom extracts and BHT. Here, Mr. Will Block has researched them finding out about their efficacy in a wide range of pathogens, including viruses and bacteria etc., there is a particular worthy note for those concerned about herpes. Hopefully, you may notice some subtle design changes. We are adapting over time to keep the magazine fresh, as well as maintaining its upto-date information. One such new feature is the media page. It will highlight our Antiaging Systems You Tube channel. To view them you will see their weblinks and QR codes. Likewise, to save paper, the full references of an article can now be found in the same way. Forever onward and upward!

Phil Micans, MS, PharmB

Editor, Aging Matters™ Magazine

Ward Dean, M.D.

Medical Director, IAS Group