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INDIAN DENTAL ACADEMY •
Leader in continuing dental education
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Learn from the mistakes of others. You can't live long enough to make them all yourself‌!
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CV
PT
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Yellow discoloration of skin & sclera due to excess serum bilirubin. > 40umol/l, (3mg/dl) Not necessarily liver disease. Conjugated & Unconjugated types Obstructive & Non Obstructive Pre-Hepatic, Hepatic & Post Hepatic types.
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•Blood •Conjugated & Conjugated •Urine – Urobilinogen •Stool – Stercobilin
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Jaundice
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Jaundice
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Post Hepatic (Obstructive) – Stone, tumor
Pre Hepatic (Acholuric) - Hemolytic
Unconjugated/Indirect Bil, pale urine
Hepatocellular Jaundice - Viral
Conjugated/Direct Bil, High colored urine,
Liver damage - unconjugated Swelling, canalicular obstruction - Conjugated
Conjugated & Unconjugated types.
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Venkatesh Murthy Shashidhar Senior Lecturer in Pathology Fiji School of Medicine
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1. 2. 3. 4.
Diffuse fibrous scarring of liver. End result of many diseases of liver. Loss of architecture Liver failure Portal Hypertension – 1. 2. 3.
Spleenomegaly Porta-systemic shunts. Ascitis
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Fibrosis
Regenerating Nodule
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Alcoholic liver disease Viral hepatitis Biliary disease Primary hemochromatosis Cryptogenic cirrhosis
60-70% 10% 5-10% 5% 10-15%
Wilson’s, α1AT def
rare
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Hepatocyte injury & necrosis Fibrous scarring Parenchymal regeneration (non functional) Loss of archetecture & Vascular disruption Portal hypertension Liver failure – Hepatic coma. •www.indiandentalacademy.com
BRAIN
Porta systemic shunts LIVER
Toxic N2 metabolites From Intestines •www.indiandentalacademy.com
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Jaundice, Abdominal Striae
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Congestive splenomegaly. Bleeding varices. Hepatocellular failure.
Hepatic encephalitis / hepatic coma.
Hepatocellular carcinoma.
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Common end result of diffuse liver damage. (common causes: Viral hepatitis & Alcohol)
Characterised by complete loss of architecture. Replaced by fibrosis & regenerating parenchymal nodules. Hepatocellular insufficiency & portal hypertension.
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