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CADYRETA
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Nesiritide Injection, Powder, Lyophilized, For Solution FOR INTRAVENOUS INFUSION ONLY Treats congestive heart failure (CHF) that is getting worse and causing breathing problems. What is nesiritide? Nesiritide relaxes and dilates blood vessels, lowering blood pressure. Nesiritide is used to improve breathing in people with congestive heart failure (CHF). Nesiritide may also be used for purposes not listed in this medication guide.
Nesiritide dosing information Usual Adult Dose for Congestive Heart Failure: Initial dose: 2 mcg/kg IV bolus, followed by 0.01 mcg/kg/min via continuous IV infusion; not to be titrated more frequently than every 3 hours to a maximum of 0.03 mcg/kg/min Comments: -This drug should not be initiated at a dose higher than the initial recommended dose. -The loading dose may not be appropriate for those with systolic blood pressure less than 110 mmHg or for patients recently treated with afterload reducers. -There is limited experience with administering this drug for longer than 96 hours; monitor blood pressure closely during administration. Use: For the treatment of acutely decompensated heart failure in patients who have dyspnea at rest or with minimal activity