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Research Institute
Trevisio
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Research Pathology CORE
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Texas Children’s Neurological Research Institute
M.D. Anderson Cancer Center
JOHNSON AVE.
BATES ST.
MAP LEGEND METRORAIL
M.D. ANDERSON BLVD.
D.
HWY 288
UNIVERSITY OF HOUSTON
BLV
Texas Children’s Texas Hospital Heart St. Luke’s Institute Hospital
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HOLCOMBE BLVD. SOUTH LOOP 610
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PARKING
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Scurlock Tower
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6670 Bertner Avenue Houston, TX 77030
houstonmethodist.org/research
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Marriot
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Jones Tower
Houston Methodist
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Research Institute
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Mary Gibb Jones Building
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ST ER LIN G
Baylor College of Medicine MO
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Trevisio
SU
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Texas Children’s Neurological Research Institute
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Texas Children’s Texas Hospital Heart St. Luke’s Institute Hospital
BATES ST. HMRI Communications & External Relations | RICORE-015 | MM | DH | xxx | 02.2015
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houstonmethodist.org/researchpathology
Houston Methodist Research Institute
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Hilton Houston Plaza/ Medical Center
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Core Director: Andreana Rivera, MD
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Research Pathology Core
6565 Fannin St., M227 Houston, TX 77030 Houston, TX 77030
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Smith Tower
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Rice Bioscience Research Collaborative
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University of Texas Health & Science
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RICE UNIVERSITY
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713.441.2662 Email: alrivera@houstonmethodist.org
Memorial Hermann Hospital
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ACCOMODATIONS
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DRYDEN/TMC METRORAIL STATION
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RESEARCH PATHOLOGY CORE LAB LOCATED IN ROOM F554, FONDREN BUILDING
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The Houston Methodist Research Institute Research Pathology Core assists with histology techniques such as tissue embedding, tissue block sectioning, and staining. The core handles both preclinical tissue samples and patient samples with required approvals.
Ben Taub General Hospital
Baylor College of Medicine
MO
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HOUSTON METHODIST RESEARCH INSTITUTE
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M.D. Anderson Cancer Center
M.D. ANDERSON BLVD.
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Mary Gibb Jones Building
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BERTNER AVE.
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Jones Tower
Houston Methodist
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Scurlock Tower
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Smith Tower
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Hilton Houston Plaza/ Medical Center
DR YD
HN
BLV
HM AIN
Rice Bioscience Research Collaborative
JO P
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RF LE
ITY
ST ER LIN G
MA
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RICE UNIVERSITY
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P Outpatient Center
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University of Texas Health & Science
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Hermann Hospital
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PARKING
BERTNER AVE.
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Research Pathology Core
The Research Pathology Core assists with routine histology techniques such as embedding tissue, sectioning tissue blocks, and staining sections. Custom tissue blocks can be prepared by the core staff, including multi-tissue arrays. Immunohistochemistry services offered include antibody characterization and optimization, and immunohistochemical and immunofluorescence staining.
SERVICES
• Specimen processing and embedding
- Assist in grossing specimens
- Tissue embedding in a cassette unless otherwise indicated
Immunohistochemistry Beta amyloid
TTF-1
CyclinD1
CD34
Pituitary hormones
WT-1
DBA-44
D2-40
Villin
Fascin
Desmin
AE1/AE3
Glycophorin
Fibronectin
Calretinin
IgA
MSA
Ber-EP4
IgD
MyoD1
Cytokeratins
IgM
Myogenin
CEA
Kappa/ Lambda
SMA
GFAP Neurofilament S-100
• Microtomy
• Design and creation of tissue microarrays
Synuclein
Tau
- Thickness of sections cut can be varied
- Performed using investigator supplied tissue or tissue from approved clinical patient samples
Synaptophysin Chromogranin
A1AT AFP
• Cryostat training and technical support
BRST-1
- Provide technical support in embedding and cutting samples
BRST-2
- Cryostat can also be reserved through iLab for self-service
CA19-9
Mammoglobin
CA125
• Tissue staining (H & E, Gram, GMS, Iron, Von Kossa)
Calponin
• Immunofluorescence (antibodies provided by investigator)
CD117
• Consultation with a pathologist upon request
ER
• Provide supplies e.g. cassettes, formalin, slides, molds, and slide boxes
CD99
CDX2
PR HCG Heppar-1
• Rush service available for an additional fee
• Immunohistochemistry (antibodies provided by core or investigator)
P63
- Titrate/optimize investigational antibodies
PSA
- DAB can provide red staining and double antibody staining
Inhibin
PLAP
RCC
E-Cadherin EMA MOC31 ALK-1 BCL-2 CD1a CD3 CD4 CD5 CD8 CD10 CD20 CD21 CD22 CD30 CD38 CD43 CD45 CD56 CD57 CD68 CD79a
Pax5 Tdt Lysozyme Adenovirus CMV EBV H. Pylori HBcAg HBsAg Herpes HSV I/II HPV HHV8 Toxo VZV BK virus HMB-45 MelanA Tyrosinase Caldesmon CD31
Note: Supply of stains is subject to availability.
Vimentin Myosin fast Myosin slow MLH1 MSH2 MSH6 Calcitonin Gastrin Glucagon Insulin NSE PTH Serotonin Somatostatin Thyroglobulin VIP P16 EGFR MIB-1 Napsin A PAX2 PAX8