Select Publications

Bu K et al. "Identifying correlations driven by influential observations in large datasets." Brief Bioinform. 2022 Jan 17;23(1):bbab482. PMID: 34864851; PMCID: PMC8769929.

Chen ST et al. "A shift in lung macrophage composition is associated with COVID-19 severity and recovery." Sci Transl Med. 2022 Sep 14;14(662):eabn5168. PMID: 36103512; PMCID: PMC10117220.

Forrest IS et al. "Genome-first recall of healthy individuals by polygenic risk score reveals differences in coronary artery calcium." Am Heart J. 2022 Aug;250:29-33. PMID: 35526571.

Frere JJ et al. "SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations after recovery." Sci Transl Med. 2022 Sep 28;14(664):eabq3059. PMID: 35857629; PMCID: PMC9210449.

Gonzalez DM et al. "Dissecting mechanisms of chamber-specific cardiac differentiation and its perturbation following retinoic acid exposure." Development. 2022 Jul 1;149(13):dev200557. PMID: 35686629; PMCID: PMC9340554.

Malle L et al. "Autoimmunity in Down's syndrome via cytokines, CD4 T cells and CD11c+ B cells." Nature. 2023 Mar;615(7951):305-314. PMID: 36813963; PMCID: PMC9945839.

Malle L et al. "Excessive negative regulation of type I interferon disrupts viral control in individuals with Down syndrome." Immunity. 2022 Nov 8;55(11):2074-2084.e5. PMID: 36243008; PMCID: PMC9649881.

Plaza-Jennings AL et al. "HIV integration in the human brain is linked to microglial activation and 3D genome remodeling." Mol Cell. 2022 Dec 15;82(24):4647-4663.e8. PMID: 36525955; PMCID: PMC9831062

Serafini RA et al "SARS-CoV-2 airway infection results in the development of somatosensory abnormalities in a hamster model " Sci Signal 2023 May 9;16(784):eade4984 PMID: 37159520

Spindler MP et al "Human gut microbiota stimulate defined innate immune responses that vary from phylum to strain " Cell Host Microbe 2022 Oct 12;30(10):1481-1498 e5 PMID: 36099923; PMCID: PMC9588646

Stalbow LA et al "The contribution of functional HNF1A variants and polygenic susceptibility to risk of type 2 diabetes in ancestrally diverse populations " Diabetologia 2023 Jan;66(1):116-126 PMID: 36216889; PMCID: PMC9729131

Zhou RW et al "A local tumor microenvironment acquired super-enhancer induces an oncogenic driver in colorectal carcinoma " Nat Commun 2022 Oct 17;13(1):6041 PMID: 36253360; PMCID: PMC9576746