Benha faculty of medicine
Course specification
Benha University Faculty of Medicine Department of Medical Biochemistry
.
Course Specification Course title: MEDICAL BIOCHEMISTRY (Code) : 07 04 First Academic Year (2012 – 2013) Department offering the course: MEDICAL BIOCHEMISTRY Academic year of M.B.& B.Ch. program: First year (2012-2013).
Date of specification approval: department council no 179, date 9- 9 - 2012 faculty council no 345 , date
18– 9 - 2012
A) Basic Information: Allocated marks:
150
marks divided into 75 marks for 1st semester and
75 marks for 2nd semester Course duration:
30 weeks of teaching divided into 15 weeks for 1st semester
and 15 weeks for 2nd semester and 2 weeks of final examination for all courses of each term giving a total of 17 weeks for each semester. Credit hours: 4 hours/week = 60 total credit hours Teaching hours:
5
hours/week = 150 total teaching hours
Final semester examination hours: 2 weeks for each semester including all courses of the semester. Benha faculty of medicine
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Course specification
Benha faculty of medicine
Semester 1st semester
Credit Hours / week
1- Lectures 2- Practical 3- Tutorial
nd
2 semester
Course specification
Total 1- Lectures 2- Practical
Total credit hours 3 hrs/week for 45 15 weeks 0.5 hour/week 6 for 12 weeks 1 hour/week 9 for 3 weeks and 0.5 hr / week for 12 weeks 15 weeks 60 3 hrs/week for 45 15 weeks 0.5 hour/week 7.5 for 15 weeks
3- Tutorial
0.5 hour/week 7.5 for 15 weeks
Total
15 weeks
60
Teaching Total hours/ week teachin g hours 3 hrs/week 45 for 15 weeks 1 hrs/week 12 for 12 weeks 2 hrs/week 18 for 3 weeks and 1 hr / week for 12 weeks 15 weeks 75 3 hrs/week 45 for 15 weeks 1 hour / 15 week for 15 weeks 1 hour / 15 week for 15 weeks 15 weeks 75
B) Professional Information: 1- Overall Aim of the Course: 1.1. To understand the essential topics of biochemistry including biomolecules of carbohydrates, lipids, proteins, nucleotides ,nucleic acids and enzymes and some minerals 1.2. To make the student oriented with the physico-chemical basis of biological systems; and the related clinical problems. 1.3. To familiarize the students with basic principles of Molecular biology and protein synthesis. 1.4. To enable the student to be familiar with biotechnology methods and their clinical implications. Benha faculty of medicine
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Course specification
Benha faculty of medicine
Course specification
2- Intended Learning Outcomes (ILOs): 2.1. Knowledge and understanding: By the end of the course, students should be able to: 2.1.1. Describe the structure and properties of carbodydrates, lipids and proteins of biological importance. 2.1.2. Describe the structure of heme and proteins of the extra-cellular matrix. 2.1.3. Demonstrate the structure and importance of immunoglobulins 2.1.4. Describe the chemistry of nucleotides and nucleic acids` 2.1.5. Point out the processes of replication, transcription and translation 2.1.6. familiarize the students with the components ,regulation and abnormalities of cell cycle together with the causes and different types of DNA mutation and repair , telomere and telomerase enzyme 2.1.7. Identify recombinant DNA biotechniques and their clinical implications. 2.1.8. Point out the significance of human genome and proteome projects and the principles of gene therapy. 2.2. Practical and Clinical Skills By the end of the course, students should be able to: 2.2.1.Perform some basic chemical tests to identify different sugars and proteins 2.2.2. Recognize how DNA and RNA are extracted and be aware of further techniques using the extracted DNA or RNA.
2.3. Professional Attitude and Behavioral skills: By the end of the course, students should be able to: 2.3.1. Demonstrate respect and Work effectively as a member or a leader of an interdisciplinary team . 2.3.2. Establish good relations with colleagues to share all types of interprofessional activities including shared learning. 2.4. Communication skills: By the end of the program the graduate will be able to: Benha faculty of medicine
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Course specification
Benha faculty of medicine
Course specification
2.4.1. Communicate clearly, sensitively and effectively with and their colleagues ,staff and co-staff. 2.4.2. Cope up with difficult situations 2.4.3. Respect superiors, colleagues and all members of the health profession. 2.5. Intellectual Skills: By the end of the course, students should be able to: 2.5.1.Determine the biochemical basis of some physiological processes occurring in the body and some clinical problems 2.5.2. Interpret the observations of chemical tests to identify unknown sugar or protein solutions. 2.5.3. Interpret the photographs of electrophoresis runs of Polymerase chain reaction (PCR) products. 2.6. General and transferable Skills: By the end of the course, students should be able to: 2.6.1.Establish life-long self-learning required for continuous professional development. 2.6.2.Use the sources of biomedical information and communication technology to remain current with advances in knowledge and practice. 2.6.3.Retrieve, manage, and manipulate information by all means, including electronic means. 2.6.4.Present information clearly in written, electronic and oral forms. 2.6.5.Establish effective interpersonal relationship to Communicate ideas and arguments . 2.6.6.Work effectively as a member or a leader of an interdisciplinary team
Benha faculty of medicine
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Course specification
Benha faculty of medicine
Course specification
3- Course contents: Semester
Subject
Lectures
Practical
Tutorial / Small group discussion credit teaching hrs hrs
teaching hrs
0.5
1
2
14
5.5
11
14
-
6 45 14
6 4.5
2
% of Total for year
Teaching hrs
4
13.5
16
21.3
10.7
3
6
22.5
31
41.3
20.7
-
3
6
17
20
26.7
13.3
12 9
1 9 2.5
2 18 5
7 60 21
8 75 28
10.7 100 37.3
5.3 50 18.7
-
-
0.5
1
2.5
3
4
2
3
-
_
0.5
1
3.5
4
5.3
2.6
4-DNA Replication, mutations and Repair , telomere & telomerase
4
-
_
0.5
1
4.5
5
6.7
5- Gene Expression and Transcription
3
-
_
0.5
1
3.5
4
5.3
1-Physical chemistry 2-Carbohydrate chemistry 3-Lipid chemistry +biological membranes 4-Minerals Total nd 2 1-Protein semester chemistry 2-Nucleotides and nucleic acid chemistry 3-Cell cycle; regulatory factors, Apoptosis, Oncogens and Carcinogene sis
credit hrs
% of Total for seme -ster
credit hrs
1st semester
credit hrs (=teaching hrs) 11
Total
Benha faculty of medicine
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Course specification
3.3
2.6
Benha faculty of medicine
Both semester -s
Course specification
6- Protein Synthesis and Modific -ations
3
-
_
0.5
1
3.5
4
5.3
2.6
7- Recombinant DNA Technology, Hybridization & blotting techniques, DNA sequencing, microarray , Gene Therapy and Human Genome and proteome projects
7
3
6
2
4
12
17
22.7
11.3
8-Enzymes Total Total
9 45 90
7.5 13.5
15 27
0.5 7.5 16.5
1 15 33
9.5 60 120
10 75 150
13.3 100 100
6.6 50 100
4- Teaching and learning methods: METHODS USED:
METHOD Lectures Practical Tutorials
evidence CDs of Lectures classes
Benha faculty of medicine
and Practical notes
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ILOs 2.1/2.3/ 2.4/2.6 2.2/2.3/2.4/2.5
Course specification
Benha faculty of medicine
Course specification
TEACHING PLAN: Lectures: 90 credit hour Lectures divided according to the current time table in general lecture halls (45 credit hours for each semester) Practical classes and tutorials: 30 credit hours (15 credit hours for each semester)
Time plan for each semester (in credit hours): Item Time schedule credit hours Lectures 3 hrs/week; 45 hours one hour each between 9 a.m. to 12 p.m. Practical 1 hour / week 30 hours for 15 weeks tutorials Total 4 hours/week 75hours
Total hours 60%
40%
100%
5- Students Assessment methods: 5-A) ATTENDANCE CRITERIA: Faculty bylaws 5-B) Assessment TOOLS: Tool Written examination Oral examination Practical and tutorial examination
Purpose (ILOs) 2.1-2.5 2.1-2.3-2.4-2.5 2.2-2.3-2.4-2.5
5-C) TIME SCHEDULE: Faculty bylaws Semester First semester
Second semester Benha faculty of medicine
Exam Week or month 1- Assessment 1 3rd week 2- Assessment 2 7th week 3- Assessment 3 13th week 4Final 1st semester 17th week (January) assessment 5- Practical assessment 17th week (January) 1- Assessment 1 4th week - 7-
Course specification
Benha faculty of medicine
Course specification
2- Assessment 2 11th week 3- Assessment 3 13th week 4Final 2nd semester 17th week assessment (June) th 5- Practical assessment 17 week (June)
5-D) Weighting System for each semester: Semester 1 semester st
Examination 1- Shock exams 2- Assessment 1 3- Assessment 2 4- Assessment 3 5- Final exam: a- Written b- Practical and tutorial exam c- Oral
nd
2
semester
% of Total Marks 2.7% 2% 2.7%
4
2.7%
37.5 10
25% 6.7%
5
6- Assignments, attendance & other activities Total 1- Shock exams 2- Assessment 1 3- Assessment 2 4- Assessment 3 5- Final exam: a- Written b- Practical and tutorial exam c- Oral
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3.3%
7.5
5%
75 4 4 5 2
50% 2.7% 2.7% 3.3% 1.3%
37.5 10
25% 6.7%
5
6- Assignments, attendance & other activities Benha faculty of medicine
Marks allocated 4 3 4
7.5
3.3% 5%
Course specification
Benha faculty of medicine
Course specification
Total 75 Both semesters Total 150 â–Ş The minimum passing & Passing grades (Faculty bylaws).
50% 100%
FORMATIVE ASSESSMENT: Student knows his marks after the Formative exams. 5-E) Examinations description: Examination 1- Shock exams 2- Assessment 1 3- Assessment 2 4- Assessment 3 5- Final exam: a- Written
b- Practical and tutorial exam
Description During lectures in the form of short question , clinical case, MCQ , right or wrong questions or choose questions One hour written paper composed of short essay questions and MCQ One hour written paper composed of short essay questions and MCQ One hour written paper composed of short essay questions and MCQ three hour written paper composed of short essay questions and MCQ. Identification of provided solutions and short questions on DNA or RNA extraction ,PCR ,Identity assessment RNA and the electrophoresis photograph of PCR run and protein run
oral examination station with 2 staff members(10-15 min c- Oral ) viva Cards 6- Assignments & Assignments on the biochemical &/or molecular basis of other activities medical subjects or problems + practical books +attendance. 6- List of references: 6.1- Basic materials: -Department book -Practical notes 6.2- Essential books (text books):
Benha faculty of medicine
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Course specification
Benha faculty of medicine
Course specification
- DM Vasudevan and Sreekumari S (2007): Text book of biochemistry for medical students. 5th edition. Jaypee Brothers Medical Publishers. -Pamela C. Champe, Richard A. Harvey and Denise R. Ferrier (2010):Lippincott's Illustrated Biochemistry. 5th edition. 6.3- Recommended books: -Robert K. Murray, David A Bender, Kathleen M. Botham, Peter J. Kennelly, Victor W. Rodwell, P. Anthony Weil (2009): Harper's Illustrated Biochemistry, 29th edition
6.4- Periodicals, Web sites:
7- Facilities required for teaching and learning: Facilities used for teaching this course include: ▪ Lecture halls: Faculty lecture hall and department lecture hall ▪ Department equipped laboratories: 3 ▪ Information technology / AV aids
Course coordinator: Prof. Dr, Amal abo el fadl Head of Department: Prof. Dr, Amal abo el fadl Date:
2012-2013
Benha faculty of medicine
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Course specification