While the world was in the throes of WWII, chemist Harley Wilhelm (PhD ‘31 chemistry) quietly plugged away at a long-shot research project in his own little corner of the Iowa State campus. His work on the Manhattan Project to purify uranium ultimately led to the end of WWII. Wilhelm’s story is one of innovation, collaboration, grit, and science. The historical narrative (on page 14) and the feature on current cutting-edge research celebrate the 75-year history of Ames National Laboratory at ISU – the only U.S. Department of Energy national laboratory located on a university campus.