August 2021—Review of Long-Acting Injectable Antipsychotics 1. All
of the following are second generation longacting antipsychotic except?
D. Both A & B
A. Aripiprazole lauroxil (Aristada®)
6. What is the primary mechanism of action of firstgeneration antipsychotics?
B. Haloperidol decanoate (Haldol®)
A. Binding to opioid receptors
C. Olanzapine pamoate (Zyprexa® Relprevv™)
B. Blocking of D2 receptors in the brain
D. Risperidone (Risperdal Consta®)
C. Dual inhibition of norepinephrine and dopamine reuptake
2. Long-acting antipsychotics can be administered in which way?
D. Stimulating serotonin receptor antagonists
A. Intramuscularly or Subcutaneously
7. What is the definite cause of schizophrenia?
B. Intrathecal or Intravenous
A. Brain development
C. Orally or Sublingual
B. Environmental factors
D. None of the above
C. Genetics D. Unknown, could be a combination of all three
3. In which of the following mental health disorders are antipsychotics used?
a. Bipolar disorder b. Major depressive disorder c. Schizophrenia d. All of the above
8.Which of the following is a positive symptom of schizophrenia? A. Hallucinations B. Lack of attention C. Loss of Interest D. Memory loss
4. A patient has been taking oral aripiprazole and is being transitioned to the long-acting injectable aripiprazole (Abilify Maintena®) . How long should the patient overlap with their oral agent?
9. All of the following are potential benefits of longacting antipsychotics except?
A. 14 days
B. Decreased hospitalizations
B. 3 weeks
C. Improved adherence
C. 3 months
D. Improved quality of life
A. Cure for schizophrenia
D. No oral overlap is necessary 10. Which long-acting antipsychotic is superior to other long-acting antipsychotics? 5. Pharmacists…
A. Aripiprazole lauroxil
A. Can administer long-acting antipsychotics in Kentucky
B. Fluphenazine decanoate
B. Can help fight the stigma that surrounds mental health disorders
D. No LAI has shown superiority over another
C. Paliperidone palmitate
C. Prescribe long-acting antipsychotics in every clinical practice setting |31| www.KPHANET.org
