Kup presentation 2017

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KOREA UNITED PHARM. INC. COMPANY PROFILE

Overseas Business Dept. February, 2017


Contents

About KUP R&D Product (IMD, Oncology, BE approved)

Global Reference

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ABOUT KUP

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Brief Introduction       

Establishment Date Business Activities

Dec. 03, 1987 Manufacture, Marketing & Sales Distribution of Pharmaceuticals and Other Healthcare Products Annual Turnover U$ 137,814,292 (2014) * Export sales - U$200million (2014) Total Assets U$ 194,952,013 (as of Dec. 31, 2014) Total Employees 1,000 employees (2016) No. of Produced Items About 300 items - *IMD, Oncology, Antibiotics, Healthcare Supplements & Foods, OTC Drugs (including Vitamins & Korean Ginseng products) Exporting countries Over 42 countries *IMD : Incrementally Modified Drug(≒Super generic)

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Brief Introduction â–ś Sejong 1 Factory Solid formulation including various IMDs has been actively producing. As the factory only for general injectable which complies to cGMP and EU-GMP has been completely constructed. Injectables are available for export markets.

Sejong 2 Factory Has been completely transformed to the factory specialized in Anti-cancer drug in 2013. From the 2015, the company is preparing for introducing cutting-edge facility and equipment aiming at cGMP approval.

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Brief Introduction New Oncology Factory (Under Construction) 2016Y No

1

2017Y

2018Y

Schedule

Design Layout

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

2

Select constructor

3

Construction

4

Eligibility

5

Manufacturing Facility Transfer

6

Pilot Production

7

GMP Accredit

8

Commercial Production

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Research & Development

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Domestic Leader, IMD

√ IMD specialized

√ 13% for R&D Investment

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Long Term Plan Currency Unit: US Dollar

IMD rate 43%

164 Mil.

IMD rate 15%

103 Mil.

113 Mil.

125 Mil.

182 Mil.

145 Mil.

GENERIC 105 Mil. 111 Mil.

111 Mil. 103 Mil.

106 Mil. 77 Mil.

97 Mil.

IMD

53 Mil. 34 Mil. 5.7 Mil.

10 Mil.

2013

2014

20.3 Mil.

2015

2016

2017

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Product Pipe-line

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PRODUCT

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Recent Data Leading Causes Of Death (Global) Ischaemic heart disease Stroke Lower respiratory infection Chronic obstructive pulmonary disease Diarrhoeal diseases HIV/AIDS Trachea, bronchus, lung cancers Diabetes mellitus Road injury Hypertensive heart disease Pre-term birth complications Liver cirrhosis Tuberculosis Kidney diseases Self-harm Liver cancer Stomach cancer Birth asphyxia and birth trauma Colon and rectum cancers Falls Alzheimer's and other dementias Breast cancer

With rising incidence of chronic diseases and cancers, the global mortality profile will shift toward non-communicable diseases by 2030

2015 Rank 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 - -

2030 Rank 1 2 4 3 9 8 6 5 7 10 19 11 - 13 16 12 14 - 15 17 18 20

Distribution of Deaths by Cause, Global, 2015 and 2030

2015

57 million deaths

68.4%

2030

70 million deaths

73.9%

Noncommunicable Diseases

Noncommunicable Diseases

Communicable Diseases

Communicable Diseases

Injuries

Injuries

Future Outlook Future healthcare delivery will focus on personalized medicine that revolves around a more customized model of care.

Source: Causes of Death 2015 and 2030 WHO), Frost & Sullivan

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KUP Product

Incrementally Modified Drugs

Anti platelet agent Cilostan CR Tab. INGREDIENT / STRENGTH INDICATION

Cilostazol 200mg Ischemic symptoms, Prevention of stroke, Cerebral infarction

Anti platelet agent Clavixin Duo Cap. INGREDIENT / STRENGTH INDICATION

Clopidogrel 75 mg + Aspirin 100 mg Atherothrombotic event, Myocardial Infarction, Acute coronary syndrome, Stroke

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KUP Product

Incrementally Modified Drugs

NSAIDs Clanza CR Tab. INGREDIENT / STRENGTH INDICATION

Aceclofenac 200mg Chronic Musculoskeletal Pain (Rheumatoid arthritis, Ankylosing spondylitis, Osteoarthritis etc)

Acute Bronchitis Kalomin Tab. INGREDIENT / STRENGTH INDICATION

Pelargonium sidoides 11%, Ethanol Extract 1235.52mg Acute bronchitis

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KUP Product

Oncology Drugs

Antibiotic Anti-cancer

Anti-Metabolite agents Epizin Inj. Gemtabin Inj.

Gemcitabine HCl

200mg, 1g, 2g

Xeltabine Tab.

Capecitabine

500mg

Pemirex Inj.

Pemetrexed

100mg, 300mg, 500mg

Microtubule Inhibitors Newtaxel –A Inj. Unitaxel Inj.

Docetaxel Paclitaxel

10mg, 50mg

Alkylating agents Platinox Inj.

Oxaliplatin

50mg

Topoisomerase Inhibitors Topocan Inj.

Topotecan HCl

4mg, 10mg

Targeting Anti-Cancer

20mg, 80mg 30mg, 100mg, 150mg

Epirubicin HCl

Erlotib Tab.

Erlotinib HCl

150mg

Glotib Tab.

Imatinib mesylate

100mg, 400mg

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KUP Product

Prescription & OTC Drugs

Gastrointestinal system Cardiovascular & Hematopoietic system Respiratory system Central Nervous system Musculo- Skeletal system Endocrine & Metabolic system Anti-Infectives Allergy&Immune system Gentio-Urinary system X-RAY Contrast medium Antidotes Vitamines & Minerals & Nutrition For The Best Global Pharmaceutical Company

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Global Reference

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Global Network & Partners Global Partners

■ Production site (Local & Global) ■ Branch office (Current) ■ Branch office (Future) ■

Uzbekistan

China

Iran

■■

Philippines

Vietnam

Colombia

Malaysia

■ ■ ■

Ecuador

Myanmar ■

Korea

Thailand ■

Indonesia

Peru

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THANK YOU FOR YOUR ATTENTION


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