Research & Innovation Annual Report by KSA&D Interactive

R E S E A R C H . I N N O VA T I O N . K N O W L E D G E . The power of enhancing clinical care.

2015 ANNUAL REPORT

Table of Contents Welcome Letter..................................................................................................................3 St. Luke’s University Health Network............................................................................4 Research & Innovation......................................................................................................6

The Research Institute..................................................................................................8

Clinical Trials................................................................................................................10

Health Care Education................................................................................................ 12

The Medical School of Temple University/ St. Luke’s University Health Network................................................................. 15 Nursing................................................................................................................. 16 Investigational Drug Studies – Department of Pharmacy................................22 St. Luke’s Global Presence...................................................................................24

Medical Textbooks Authored by St. Luke’s Research Faculty...................................26

Textbook Chapters Authored by St. Luke’s Research Faculty..................................26

Departments

Anesthesiology............................................................................................................28

Behavioral Health Services........................................................................................ 30

Critical Care.................................................................................................................32

Dentistry......................................................................................................................35

Dermatology...............................................................................................................39

Emergency Medicine.................................................................................................. 44

Family Medicine..........................................................................................................54

Geriatric Medicine...................................................................................................... 60

Heart & Vascular.........................................................................................................62

Internal Medicine & Subspecialties........................................................................... 68

Neurosciences.............................................................................................................76

Obstetrics & Gynecology............................................................................................79

Oncology.................................................................................................................... 84

Orthopaedic Surgery.................................................................................................. 88

Other (Ophthalmology and Otolaryngology / Ear-Nose-Throat) .......................... 94

Pain and Palliative Care Services................................................................................95

Pathology.................................................................................................................... 96

Pediatrics & Neonatology.......................................................................................... 98

Physical and Occupational Therapy and Speech Language Pathology..................102

Podiatry & Foot Care.................................................................................................106

Radiology................................................................................................................... 110 Surgery........................................................................................................................112

Traumatology, Surgical Critical Care & Acute Care Surgery....................................116

Wound Care Center and Hyperbaric Medicine........................................................ 122

President & CEO Richard A. Anderson Vice President, Marketing & Public Relations Ken Szydlow Editor-in-Chief Dorrit Trate Art Director Jen Rimonneau Research Contributors Tracy Butryn Stanislaw Stawicki Jill Stoltzfus Contributing Designers Lori Diehl Erin Joseph Heather Kade Contributing Photographers Anne Kemp Anita Sergent Betsy Toole Contributing Writers Stephen Andrews Karen Boksan Manny Changalis Mary DeHaven Tyler DeHaven Andrea Hahn Susan Kovacs Mariella Miller James P. Orlando Denise Rader Kate Raymond Susan Ross Lindsey Solovey Gail Wainwright

Contributing Medical Writers Dr. Sanjiv Agarwala Dr. James Airoldi Michael Amory, OTR/L Dr. James Anasti Dr. Brent Bernstein Dr. Aldo Carmona Dr. James Cipolla Dr. William De Long Dr. Robert deQuevedo Peter Deringer, RN Dr. Ray Durkin Dr. Steven Falowski Dr. Gloria Fioravanti Dr. Hal Folander Dr. William Hoff Dr. Jennifer Janco Dr. Rebecca Jeanmonod Stephen Kareha, DPT Dr. Robert Lagan Dr. Marian McDonald Dr. Scott Melanson Dr. Alaa-Elin Mira Dr. Hugh Moulding Dr. Sudip Nanda Darlene Nemeth Dr. Stephen Olenchock Dr. Mohammed Qahash Susan Reed, RPH Dr. Lee Riley Dr. Richard Sharpe Dr. Jamshid Shirani Dr. Jamie Thomas Dr. Peter Thomas Dr. David Yen Dr. Israel Zighelboim

Welcome to the Inaugural Issue of Research & Innovation St. Luke’s University Health Network (SLUHN) is committed to providing our patients and community with the best care, and to advancing medical practice and technologies through quality research and innovation. We are fortunate to have a world-class team of dedicated research professionals who specialize in a broad range of highly specialized skills, including biostatistics, data collection, grant preparation, regulatory compliance, clinical trials coordination, manuscript writing, among many others. The Department of Research & Innovation, actively facilitates and coordinates research efforts across SLUHN. This includes: • The development and conduct of both internally driven studies and externally sponsored clinical trials • Faculty engagement with medical students, residents, and fellows • Sponsoring educational opportunities for SLUHN staff in the areas of research and clinical trials • Compliance and regulations • Statistical analysis of research and quality improvement projects. With a team of dedicated and experienced clinicians and support staff, we are committed to taking health care to the next level and providing the best treatment for our patients. Sincerely,

Stanislaw P. Stawicki, MD, MBA, FACS Chair & Network Medical Director Department of Research & Innovation

Tracy Butryn, MS, CCRP, CHRC Network Director Clinical Trials & Research

Jill C. Stoltzfus, PhD Director The Research Institute

Co-Director Post-Doctoral Research Program

RESEARCH.SLUHN.ORG | 3

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

St. Luke’s University Health Network Over the past 30 years, St. Luke’s has grown from a large community hospital to the region’s largest hospital system with six — and soon to be seven — hospitals. Being one of the fastest growing health systems did not happen spontaneously. Rather, our commitment to a strategic vision has enabled us to provide our communities’ residents with the best quality, most accessible and innovative health care. As health care delivery changes and medicine advances, we continuously fine-tune our vision as we aspire to bring the latest procedures, technology and treatments to our patients. Our dedication to medical research and education has, in part, made this happen. As the region’s largest hospital system, we’ve taken steps to ensure that we’re leading the way in the Lehigh Valley and beyond. We think big. We dream big. And we get the big picture. Here are some facts that you might not know about St. Luke’s. • In Fall 2016, St. Luke’s will open its seventh hospital. It will be located in Monroe County and will continue to extend our reach well into the Pocono Mountain region. • St. Luke’s is the region’s leader in patient-centered care with more NCQA-certified Medical Home physician practices than any other area hospital. • St. Luke’s is an International Show Site for GE Healthcare. • St. Luke’s has the largest geographic reach and is the only regional hospital network to span two states.

• St. Luke’s is the only hospital in the Lehigh Valley and, in fact, in Pennsylvania, New Jersey and New York to be named one of Truven Health Analytics™ 100 Top Hospitals in the nation. • St. Luke’s is the region’s only trauma network. • St. Luke’s has been honored with more than 120 health care quality awards in the past 20 years, including US News & World Report, HealthGrades and Premier. • St. Luke’s has 31 physical therapy locations throughout Lehigh, Northampton, Schuylkill, Carbon, Luzerne and Monroe counties in Pennsylvania and Warren County in New Jersey. • St. Luke’s is the largest provider of Sports Medicine in the region. • St. Luke’s provides expansive home health and hospice services in seven counties.

• St. Luke’s has established the region’s first and only medical school.

We continuously fine-tune our vision as we aspire to bring the latest procedures, technology and treatments to our patients.

St. Luke’s University Hospital – Bethlehem

St. Luke’s Allentown Campus

St. Luke’s Anderson Campus

St. Luke’s Miners Campus

St. Luke’s Quakertown Campus ng ni 16 e p 0 O ll 2 Fa

St. Luke’s Warren Campus

St. Luke’s Monroe Campus

RESEARCH.SLUHN.ORG | 5

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION 6

Research & Innovation St. Luke’s University Health Network’s Research & Innovation encompasses many departments and initiatives that further medical study, exploration and education. Not just a worthwhile pursuit, research & innovation benefits our patients by offering advanced treatments and procedures and by attracting exceptional health care professionals determined to advance their fields. THE RESEARCH & INNOVATION SECTION CONSISTS OF: • The Research Institute • Clinical Trials • Health Care Education, including our Medical School and School of Nursing RESEARCH FACULTY COUNCIL The Research Faculty Council oversees and advises research and innovation. Council members are: • Sanjiv Agarwala, MD

• Maher El Chaar, MD, FACS, FASMBS

• Philip Salen, MD

• James Anasti, MD

• Brian Hoey, MD

• Lisa Spacek, MD, PhD

• Jennifer Axelband, DO

• Rebecca Jeanmonod, MD

• Jamshid Shirani, MD

• Ric Baxter, MD

• Stephen Kareha, DPT

• Joan Snyder, MS, BSN, RN, CPHQ

• Brent Bernstein, DPM

• Daniel Longyhore, PharmD, BCACP

• Stan Stawicki, MD, FACS

• Bill Burfeind, MD

• Sudip Nanda, MD

• Jill Stoltzfus, PhD (Chair)

• Tracy Butryn, MS, CCRP, CHRC

• JP Orlando, EdD

• Nicholas Taylor, MD

• Greg Carolan, MD

• Marc Portner, MD

• Pamela Valenza, MD

• Maria Collette, MLS

• Peter Puleo, MD

• Gail Wainwright, MSN, RN

• Kathleen Dave, PhD

• Mohammed Qahash, DDS

• Bob Weigand, MS

• Nimisha Deb, MD

• Kathy Ramson, DNP, RN

• Judy Zarzeka, RN, BSN

• William De Long, MD

• Lee Riley, MD, PhD

• Peter Deringer, RN, MA, NE-BC

• Joel Rosenfeld, MD, MEd, FACS

Not just a worthwhile pursuit, research and innovation benefits our patients by offering advanced treatments and procedures

St. Luke’s University Health Network was named one of the nation’s 100 Top Hospitals® by Truven Health Analytics™, a leading provider of data-driven analytics and solutions to improve the cost and quality of health care. RESEARCH POLICIES AND PROCEDURES WORKGROUP Also providing oversight is the Research Policies and Procedures Workgroup. Members are: • Tracy Butryn, MS, CCRP, CHRC

• JP Orlando, EdD

• Walter Harrison, RN, BSN

• Stan Stawicki, MD, FACS

• Jane Markson, Esquire

• Jill Stoltzfus, PhD

• Amanda Mazza, MBA

RESEARCH.SLUHN.ORG | 7

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

The Research Institute Under the leadership of Dr. Jill C. Stoltzfus, the Research Institute provides critical guidance to employees of St. Luke’s University Health Network regarding research opportunities. This includes students, faculty members, physicians, nurses, therapists and other employees. Dr. Stoltzfus has also been the principal organizer of the annual St. Luke’s Research Symposium for Residents and Fellows — a celebration of research that dates back more than 20 years. The 2014 Residents’ and Fellows’ Research Symposium was held in Laros Auditorium on June 12, 2014, and featured oral and poster presentation competitions. Physician judges, Bill Burfeind, MD, Peter Ender, MD and Dianne Jacobetz, MD, evaluated the presentations and selected the following winners:

Dr. Angel Gonzalez (OB-GYN), “A Search for Novel Risk Factors for Obstetric Trauma”

1st Place Oral Presentation Dr. Dan Avery (Orthopaedic Surgery), “SurgeonDetermined Visualization in Shoulder Arthroscopy: A Randomized, Blinded, Controlled Trial Comparing Irrigation Fluid with and without Epinephrine”

Nourse R, Reade C, Stoltzfus J, Mittal V. Demographics, Clinical Characteristics, and Treatment of Aggressive Patients Admitted to the Acute Behavioral Unit of a Community General Hospital: A Prospective Observational Study. Primary Care Companion for CNS Disorders. 2014; 16(3). doi: 10.4088/PCC.13m01589.

2nd Place Oral Presentation Dr. Kathryn Balinger (General Surgery), “Will I Miss an Aneurysm? The Role of CTA in Traumatic Subarachnoid Hemorrhage” 1st Place Poster Presentation (two-way tie) Dr. Christin Gillier (co-first author, OB-GYN) and Dr. Jennifer Myers (co-first author, OB-GYN), “The Effects of Abdominal Binders on Pain and Distress in Post-Cesarean Section Patients: A Prospective Randomized Controlled Trial” Dr. Keith Habeeb (Emergency Medicine), “Incoming Resident Perception of Competency and Knowledge Base of Basic Medical Procedure Enhanced by Procedural Workshop and Educational Material”

Dr. Marcela Perez Acosta (Internal Medicine), “Red Blood Cell Distribution Width Variation in Sepsis: A Marker of SIRS or Bacteremia?” THE RESEARCH INSTITUTE: PUBLICATIONS Mersky A, Eberhardt M, Overfield P, Melanson S, Stoltzfus J, Pretosh J. The Effect of the Repeal of the Pennsylvania Helmet Law on the Severity of Head and Neck Injuries Sustained in Motorcycle Accidents. Annals of Emergency Medicine (Impact Factor: 4.33). Sept 2009; 54(3). doi: 10.1016/j2009.06.332.

Paulik Ramson K, Dudjak L, August-Brady M, Stoltzfus J, Thomas P. Implementing an Acuity-Adaptable Care Model in a Rural Hospital Setting. Journal of Nursing Administration. Sept 2013; 43(9): 455-460. doi: 10.1097/NNA.0b013e3182a23b9b. Stawicki SP, Stoltzfus JC, Aggarwal P, Bhoi S, Bhatt S, Kalra OP, Bhalla A, Hoey BA, Galwankar SC, Paladino L, Papadimos TJ. Academic College of Emergency Experts in India’s INDO-US Joint Working Group and OPUS12 Foundation Consensus Statement on Creating a Coordinated, Multi-Disciplinary, Patient-Centered, Global Point-of-Care Biomarker Discovery Network. International Journal of Critical Illness & Injury Science. July 2014; 4(3): 200-208. doi: 10.4103/2229-5151.141398.

2nd Place Poster Presentation (three-way tie) Dr. Daniel Evans (Emergency Medicine), “NEXUS in the Elderly Fall Patient: What is Distracting?”

The Research Institute provides critical guidance to employees of St. Luke’s University Health Network regarding footer callout research text opportunities.

Stoltzfus J, Nishijima D, Melnikow J. Commentary: Why Quantile Regression Makes Good Sense for Analyzing Economic Outcomes in Medical Research. Academic Emergency Medicine. July 2012; 19(7): 850-851. doi: 10.1111/j.1553-2712.2012.01386.x. Stoltzfus J. Logistic Regression: a Brief Primer. Academic Emergency Medicine. Oct 2011; 18(10): 1099-1104. doi: 10.1111/j.1553-2712.2011.01185.x. Waninger K, Goodbred A, Vanic K, Hauth J, Onia J, Stoltzfus J, Melanson S. Adequate Performance of Cardiopulmonary Resuscitation Techniques During Simulated Cardiac Arrest Over and Under Protective Equipment in Football. Clinical Journal of Sport Medicine. July 2014; 24(4): 280-283. doi: 10.1097/JSM.0000000000000022.

THE RESEARCH INSTITUTE: PRESENTATIONS Eberhardt M, Mersky A, Goldman E, Melanson S, Prestosh J, Stoltzfus J. The Effect of the Repeal of the Pennsylvania Helmet Law on the Severity of Head and Neck Injuries Sustained in Accidents. ACEP Research Symposium; Oct 2009; Boston, MA. Finan M, Hahn D, Stoltzfus J, Eberhardt M. How Well Do Academic and Community ED Physicians Follow Decision Rules for Pulmonary Embolism. Poster. ACEP Research Forum; Oct 2014; Chicago, IL. Kadish J, Salen P, Genzlinger M, Stoltzfus J, Grossman M. An Exploratory Study Comparing Ketamine v. Etomidate for Rapid Sequence Intubation in Traumatically Injured Patients. Poster presentation #74. ACEP Scientific Assembly; Oct 2013; Seattle, WA. Loffredo D, Salen P, Guerrieri E, Stoltzfus J. Parenteral V. Oral Phytonadione Administration For Coumadin Induced Coagulopathy. Poster presentation #88. ACEP Scientific Assembly; Oct 2013; Seattle, WA.

RESEARCH.SLUHN.ORG | 9

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Clinical Trials The St. Luke’s University Health Network Clinical Trials Office (CTO) supports and oversees the conduct and management of sponsored clinical research across SLUHN. Under the direction of Tracy Butryn, MS, CCRP, the CTO integrates both the clinical operational team and the research administration team to ensure that all aspects of clinical research are performed in compliance with regulations and policies, and workflow is efficient and streamlined through a centralized office. Our team of expert and dedicated clinicians and staff conduct research across a multitude of therapeutic areas in both outpatient and inpatient settings. The CTO’s primary responsibilities include: • Serving as the official point of contact for various sponsors of scientific and scholarly activity. • Facilitating the relationship and research activities between SLUHN investigators and sponsors throughout the entire protocol lifecycle. • Providing education and resources to support the conduct of sponsored programs. • Ensuring sponsored projects are managed in accordance with local, state, and federal regulations, as well as SLUHN policies. • Coordinating all clinical research activities including operational, clinical, regulatory, contracts, budgets, billing compliance, and financial management functions. • Ensuring overall compliance by establishing quality control measures and processes. For information about specific trials, click here.

Our team of expert and dedicated clinicians and staff conduct research across a multitude of therapeutic areas in both outpatient and inpatient settings.

RESEARCH.SLUHN.ORG | 11

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Health Care Education Health care education is a major focus of St. Luke’s University Health Network. Each year, more than 1,000 students receive clinical instruction at St. Luke’s, making it the largest community-based teaching hospital in the area. Annually, St. Luke’s educates more students than any other similar institution. GRADUATE MEDICAL EDUCATION St. Luke’s is dedicated to quality medical education coupled with compassionate patient-centered, technologically sophisticated care. The goal of the graduate medical education program is to train young physicians who will have the knowledge and skills to enter private practice and/or go into fellowships for further training. More than 180 fellows, residents and interns train at St. Luke’s, which is one of only 400 members of the prestigious Council of Teaching Hospitals.

QUICK FACTS 23 accredited, graduate medical education programs (doctoral-level) • 13 Accreditation Council for Graduate Medical Education • 5 American Osteopathic Association • 2 Council on Podiatric Medical Education • 1 Commission on Dental Accreditation • 1 American Society of Health-System Pharmacists • 1 American Board of Physical Therapy Residency/Fellowship

184 house staff • 169 residents • 15 fellows

Unaccredited, graduate medical education programs (doctoral-level) • 1 fellow

Annually, St. Luke’s educates more students than any other similar institution.

RESIDENCY PROGRAMS • Dental • Emergency Medicine • Family Medicine • Family Medicine — St. Luke’s Hospital – Warren Campus • General Surgery • Internal Medicine (ACGME) • Internal Medicine (AOA) • Obstetrics/Gynecology • Orthopaedic Surgery • Pharmacy • Podiatry • Transitional Year FELLOWSHIP & INTERNSHIP PROGRAMS • Cardiology • Geriatric Medicine • Hospice Palliative Medicine • Primary Care Sports Medicine • Surgical Critical Care • Osteopathic Traditional Rotating Internship ADVANCED PRACTITIONER PROGRAMS • Emergency Medicine Post Residency • Trauma Critical Care (PA/NP) GME RELATED PRESENTATIONS Cossey K, Jeanmonod R. Impact of Language Discordance on Door-to-Room Time and Patient Satisfaction in Triage. Poster. American College of Emergency Physicians Scientific Assembly, 2012, Denver, CO. Damewood S, Jeanmonod D, Cadigan B. Teaching the Focused Assessment with Sonography in Trauma (FAST) Exam: Is an Ultrasound Mannequin Simulator as Good as or Better than Live Models for Practical Training? ACEP National Scientific Assembly, Oct 2009, Boston MA. Abstract published in Annals of Emergency Medicine. 2009. Finan M, Jeanmonod R, Melanson S. The Impact of Standardized Testing and Interview Scoring on Emergency Medicine Applicants’ Rank Position. Oral. SLUHN Research Forum, June 2013, Bethlehem, PA. Habeeb K, Axelband J, Stoltzfus J, Prestosh J, Melanson S. Incoming Resident Perception of Competency and Knowledge Base of Basic Medical Procedures Enhanced by Procedural Workshop and Educational Material. Oral. American College of Osteopathic Emergency Medicine, Oct 2013, San Diego, CA.

RESEARCH.SLUHN.ORG | 13

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

GME RELATED PUBLICATIONS

SIMULATION LABORATORY PUBLICATIONS

DelCollo J; Jeanmonod D; Dombchewsky O; Reiter M; Jeanmonod RA. Comparison of Resident and Mid-level Provider Productivity and Patient Satisfaction in an Emergency Department Fast Track. Emergency Medicine Journal. Jan 2013; 30(1): e12. doi: 10.1136/ emermed-2011-200572.

Jeanmonod R, Barcomb T, Pattee J. The Perceived Impact of Precepting Medical Students on Residents’ Clinical Work and Education. Poster. American College of Emergency Physicians Scientific Assembly, Boston, MA 2009. Annals of Emergency Medicine 54(3): S11, 2009.

Jeanmonod R, Damewood S, Brook C. Resident Productivity: Trends over Consecutive Shifts. International Journal of Emergency Medicine. May 2009; 2(2): 107-10.

QUICK FACTS RESIDENCY PROGRAM SLOTS

FELLOWSHIP PROGRAMS

• Dental Residency

• Cardiology Fellowship

• Emergency Medicine Residency

• Geriatric Medicine Fellowship

• Family Medicine Residency – Bethlehem Campus

• Hospice & Palliative Care Medicine

• Family Medicine Residency – Warren Campus

• Podiatry/Dermatology Fellowship

• Sports Medicine Fellowship

• General Surgery Residency

• Surgical Critical Care Fellowship

• Internal Medicine Residency

• Obstetrics and Gynecology Residency

• Orthopaedic Physical Therapy Residency (new program)

• Orthopaedic Surgery Residency

• Pharmacy Residency

• Podiatry Residency

• Transitional Year Residency

GRAND TOTAL Post-Doctoral Research Programs

Waninger K, Goodbred A, Vanic K, Hauth J, Onia J, Stoltzfus J, Melanson S. Adequate Performance of Cardiopulmonary Resuscitation Techniques during Simulated Cardiac Arrest over and under Protective Equipment in Football. Clinical Journal of Sports Medicine. July 2014; 24(4): 280-3. doi: 10.1097/ JSM.0000000000000022.

Non-Accredited • Female Pelvic Medicine and Reconstructive Surgery Fellowship

185 3 New

The Medical School of Temple University/ St. Luke’s University Health Network The ONLY Medical School of the Greater Lehigh Valley The Temple/St. Luke’s School of Medicine combines an enthusiastic faculty, eager to share their knowledge and skills, with cutting edge medicine and technology. Students experience the energy and excitement of a new, innovative program that is firmly grounded in outstanding practices resulting from decades of experience. The small class size offers students a supportive and interactive learning environment in a friendly, collegial setting that enables them to achieve their full potential. During their first year of their medical degree program, students attend the Temple University School of Medicine Campus in Philadelphia and then complete years two, three and four at St. Luke’s University Health Network in Bethlehem under the direction of Dr. Joel C. Rosenfeld. Chief Academic Officer for St. Luke’s University Health Network’s Graduate Medical Education programs, he also manages the Network’s residency and fellowship programs and serves as a professor of surgery at Temple University School of Medicine. For more information about the Temple/St. Luke’s School of Medicine, click here.

RESEARCH.SLUHN.ORG | 15

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Nursing The advancement of nursing has always been on the forefront of St. Luke’s University Health Network. Among the many testaments of this long-standing commitment is the St. Luke’s School of Nursing. Founded in 1884, the school is the oldest continuously operating diploma-based nursing school in the nation. During the 20-month nursing curriculum, students receive 900 hours of clinical practice in a variety of health care settings preparing them for success on State Boards and careers in professional nursing. St. Luke’s University Health Network also offers a 12-month acute care advanced practitioner postgraduate fellowship with tracks in emergency medicine/critical care or critical care/surgical subspecialty. Additionally, it serves as a clinical site for numerous nursing masters/doctorate practicums and internships. Employing more than 2,200 nurses, St. Luke’s University Health Network has been successful in attracting, cultivating and retaining nurses with extensive experience and education. Eight nurses have attained doctorate degrees in nursing and well over 100 have master’s degrees. Nursing leadership strongly supports and promotes professional inquiry as an essential component to the continued growth of a healthy evidence-based practice environment. Strong education and interdisciplinary partnerships have allowed St. Luke’s to excel in evidence-based and quality initiatives. An Evidencebased Practice and Standards Council oversees important committees including the Nursing Policy and Procedure, EBP Education, and Nursing Research and Scholarship Committees. At the 2014 Nursing Research and Scholarship Day event, the first annual Robin Haff Research and Scholarship Award was presented. The award, sponsored by Dr. Vincent Lucente, honors the late Robin Haff, who was a committed and passionate nurse researcher. The award is presented to a St. Luke’s nurse who exemplifies those same qualities.

The Center for Nursing Excellence at St. Luke’s was created to provide a forum to support nurses in their lifelong commitment to learning and self-development. Managed by nurses for the purpose of advancing the profession of nursing, it provides scholarships for nurses to pursue BSN, MSN or doctorate degrees, offers nurses opportunities to obtain specialty certifications and hosts CEC conferences, often featuring national keynote speakers. In addition, the Center provides opportunities for nurses to attend national conferences and funds research projects. Nurses are supported and highly encouraged to share their research and experience through publications and presentations at conferences. With nurses in many key leadership positions, nurses are highly respected members of the St. Luke’s health care team. Nurses often initiate and lead projects that improve patient care. In 2014 the Hospital Association of Pennsylvania (HAP) recognized several of these initiatives. HAP awarded St. Luke’s four Achievement Awards, which honor hospitals and health systems for their innovation, creativity and commitment to patient care. In addition, nursing’s strong evidencebased practice and culture of safety is essential to the network’s success in earning such prestigious awards as Truven and Leapfrog. Nursing’s latest commitment to the advancement of evidence-based practice, performance improvement (PI) and research is evident in the new nursing fellowship program. The fellowship provides future nurse leaders with advanced education, coaching and mentoring, thereby preparing them to help lead meaningful and significant PI and research projects.

Founded in 1884, the school is the oldest continuously operating diploma-based nursing school in the nation.

PUBLICATIONS: MEDICAL SURGICAL AND CRITICAL CARE NURSING Colancecco EM, Moriarty S, Litak L. None Shall Pass... Without Answering the Call Bell. Nursing. Jan 2014; 44(1); 16-7. ISSN: 0360-4039 PMID: 24346364 CINAHL AN: 2012418929. Fitzgibbon M, Lorenz R, Lach H. Medication Reconciliation. (includes abstract); Journal of Gerontological Nursing. Dec 2013; 39(12): 22-9. ISSN: 0098-9134 PMIS: 24102104 CINAHL AN: 2012387788. Ramson KP, Dudjak L, August-Brady M, Stoltzfus J, Thomas P. Implementing an AcuityAdaptable Care Model in a Rural Hospital Setting. Journal of Nursing Administration. Sept 2013; 43(9): 455-60. ISSN: 0002-0443 PMID: 23958524 CINAHL AN: 2012298720. Doi: 10.1097/NNA.0b013e3182a23b9b.

PRESENTATIONS: MEDICAL SURGICAL AND CRITICAL CARE NURSING Knecht C, Tarone D. Reducing Hospital Acquired Infections: Keep the Lines Clean and Clear. Premier’s Annual Breakthroughs Conference; June 2012; Nashville, TN. Kupec C. Blood Management: Multi-disciplinary Strategies. Premier’s Annual Breakthroughs Conference; June 2012; Nashville, TN. Kupec C. Effective Blood Management in the Elective Total Joint Replacement Patient. Premier Breakthroughs Conference; June 2011; Nashville, TN. Kupec, C. Cost of Care- Blood Utilization. Premier’s Quest/Partnership for Patients National Meeting; December 2012; Orlando, FL. Martiensen M, Sanches S, & Sargent K. Success with Unit-based Care Modeling. Premier Breakthroughs Conference & Exhibition; June 2013; San Antonio, TX. McKeon S. Organ Donation: Building a High Functioning Team. Premier’s Annual Breakthroughs Conference; June 2012; Nashville, TN.

RESEARCH.SLUHN.ORG | 17

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

McKeon S. Eliminate VAP: Comprehensive Unit Based Safety Program (CUSP) for Elimination of Ventilator Associated Pneumonia (VAP). Premier’s Annual Breakthroughs Conference; June 2013; San Antonio, TX. Morgan L, Sargent K. Improving the Patient’s Perception of Care. Panel Discussion. Premier’s Breakthroughs Conference; June 2014; San Antonio, TX. Ramson K, Horgash J. Creating a Critical Care Culture of Safety. Premier’s Annual Breakthroughs Conference; June 2012; Nashville, TN. Ramson K. Implementing a Blood Management Program. Panel Discussion. Premier Breakthroughs Conference, June 2011; Nashville, TN. PUBLICATIONS: TRAUMA NURSING Hoff J, Grell J, Lohrman N, Stehly C, Stoltzfus J, Wainwright G, Hoff WS. Distracted Driving and Implications for Injury Prevention in Adults (includes abstract). Journal of Trauma Nursing. Jan-Mar 2013; 20(1): 31-6. (journal article - CEU, exam questions, research, tables/charts) ISSN: 1078-7496 PMID: 23459430 CINAHL AN: 2012065446. Doi: 0.1097/ JTN.0b013e318286616c. Wilson L, Wainwright G, Stehly C, Stoltzfus J, Hoff W. Assessing the Academic and Professional Needs of Trauma Nurse Practitioners and Physician Assistants (includes abstract). Journal of Trauma Nursing. Jan-Mar 2013; 20 (1): 51-5. (journal article - research, tables/ charts) ISSN: 1078-7496 PMID: 23459433 CINAHL AN: 2012065449. PRESENTATIONS: TRAUMA NURSING Grell J. Surgical Trauma Intensive Care Unit Hospital Acquired Pressure Ulcers Associated with Cervical Collar Use in Trauma. The 16th Annual Pennsylvania Trauma Systems Foundation (PTSF) Conference; Oct 2012; Harrisburg, PA. Leshko K. C-spine Stabilization in the Trauma Patient. Pennsylvania Emergency Health Services Council (PEHSC), Annual EMS Conference; September 2014; Lancaster, PA.

Leshko K. Level IV Trauma Program Start-up in a Rural Community in Pennsylvania. Poster. Premier Breakthroughs Conference; June 2014; San Antonio, TX. Leshko K. Rural Trauma System Development in PA: If we build will they come? PA Emergency Nurses Association (ENA) State Council Annual Conference; June 2014; State College, PA. Lohrman N, Hoff W. Trauma Department Leading by Example: Utilization of a Massive Transfusion Protocols across a Hospital System. 16th Annual Pennsylvania Trauma Systems Foundation (PTSF) Conference; Oct 2012; Harrisburg, PA. Trapani P. Surgical Trauma Intensive Care Unit Hospital Acquired Pressure Ulcers Associated with Cervical Collar Use in Trauma. Premier Breakthroughs Conference; June 2014; San Antonio, TX. Trapani P. Surgical Trauma Intensive Care Unit Hospital Acquired Pressure Ulcers Associated with Cervical Collar Use in Trauma. The 16th Annual Pennsylvania Trauma Systems Foundation (PTSF) Conference; Oct 2012; Harrisburg, PA. Trapani P. Surgical Trauma Intensive Care Unit Hospital Acquired Pressure Ulcers Associated with Cervical Collar Use in Trauma. Poster. Society of Trauma Nurses National Conference; April 2012; Atlanta, GA. PUBLICATIONS: OBSTETRICS & GYNECOLOGY NURSING Martin M. Building Better Communication for Safer Patient Care (includes abstract). Journal of Obstetric, Gynecologic & Neonatal Nursing. Jun 2014; 43(Supp 1): S12. (journal article) ISSN: 0884-2175 CINAHL AN: 2012663182.

PRESENTATIONS: OBSTETRICS & GYNECOLOGY NURSING Balagach A, Althauser C, Martin M, Walp S. Non-Coached Pushing in the Second Stage of Labor. The Association of Women’s Health, Obstetric and Neonatal Nurses Convention; June 2012; National Harbor, MD. Abstract included in a conference proceedings supplement to the Journal of Obstetrical, Gynecological, and Neonatal Nursing. Martin M. The Safe Birth Journey…Beyond the Bundles Tachysystole Surveillance and Management during Oxytocin Administration. The Association of Women’s Health, Obstetric and Neonatal Nurses Convention; June 2013; Nashville, TN. Nunemacher K, Merola J. Applying a Just Culture of Safety to Operative Vaginal Delivery. Concurrent Session Discussion. Premier Breakthroughs Conference, June 2011, Nashville, TN. Nunemacher K. Changing Obstetrical Practice: Delivery after 39 weeks. Premier Annual Breakthroughs Conference; June 2012; Nashville, TN. Nunemacher K. Quality Resources Presentation: Pennsylvania OB Adverse Events Collaborative: Early Elective Delivery Perinatal Care Core Measures - 01 Network Call, Oct 2012; Philadelphia, PA. Nunemacher K. Quality Resources Rapid Cycle Reduction of “Elective” Delivery by Team Concepts and Culture of Safety Presentation. HAP (Hospital and Health System Association of PA) Patient Safety & Quality Symposium; Sept 2012; Lancaster, PA. Nunemacher K. Quality Resources Webinar Presentation: Premier Partnership for Patients. OB Early Elective Delivery Mini Collaborative; Oct 2012.

RESEARCH.SLUHN.ORG | 19

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

PRESENTATIONS: PERIOPERATIVE NURSING Buono A. A Powerful Meeting. Poster. AORN Surgical Conference and Expo; March 2014; Denver, CO. LeCoultre M, Rehnert, C. Prophylactic Antibiotic Selection for Surgical Patients. Poster. Received Clinical Excellence Award. AORN Surgical Conference and Expo; March 2013; Chicago, IL.

PRESENTATIONS: HOME HEALTH AND HOSPICE NURSING Sargent K. Home Health Special Interests Group panelist. Press Ganey Webinar; 2013.

PUBLICATIONS: BEHAVIORAL HEALTH NURSING

PUBLICATIONS: NURSE PRACTITIONER

Nourse R, Reade C, Stoltzfus J, Mittal V. Demographics, Clinical Characteristics, and Treatment of Aggressive Patients Admitted to the Acute Behavioral Unit of a Community General Hospital: A Prospective Observational Study. http://www.psychiatrist.com/ pcc/abstracts/abstracts. asp?abstract=13m01589/13m01589.htm Oct. 2013; posted to the Primary Care Companion for CNS Disorders website.

Sonday C, Grecsek E, Casino PD. Rapid Response Teams: NPs Lead the Way (includes abstract). Nurse Practitioner. May 2010; 35(5): 40-6. ISSN: 0361-1817 PMID: 20395767 CINAHL AN: 2010644547

Nourse R, Reade C. Intervening to Prevent Violence in Psychiatric Units. Nursing. July 2012; 42(7): 14-7. Doi:10.1097/01.NURSE.0000415320.99350.ac. PRESENTATIONS: BEHAVIORAL HEALTH NURSING Reade C, Nourse R. Demographics, Clinical Characteristics, and Symptoms Severity of Aggressive Patients Admitted to the Acute Behavioral Health Unit of a Community General Hospital: A Prospective Study. American Psychiatric Nursing Association National Conference; Oct 2013; San Antonio, TX. Reade C, Nourse R. Implementation of Evidence-Based Discharge Planning Practices to Decrease Psychiatric Readmission Rates. American Psychiatric Nursing Conference; Nov 2012; Pittsburgh, PA. PUBLICATIONS: HOME HEALTH AND HOSPICE NURSING Giovanni L. End-of-Life Care in the United States: Current Reality and Future Promise - A Policy Review. Nursing Economics, The Journal for Health Care Leaders. May/June 2012; 30: 127-135. Nemeth T, Provini B. Collaboration Impacts End of Life Care. Pennsylvania Nurse. Fall 2012; 67(3): 15-18.

Weigand M. Nurse to Nurse Communication in Home Health, Pennsylvania Nurse. Fall 2012; 67(3): 19-22.

PRESENTATIONS: NURSE PRACTITIONER Culligan L. The Importance of Developing an Advanced Practitioner Committee for your Hospital. Pennsylvania Coalition of Nurse Practitioners State Conference; Nov 2013; Lancaster, PA. Szoke A. The Effects of Antiplatelet Agents on Mild Traumatic Brain Injured Patients: A Comparative Study Assessing Neurologic Deterioration and Patient Based Outcomes. American Academy of Nurse Practitioner National Conference; June, 2014; Nashville, TN. Szoke A. Traumatic Event and the Hybrid Operating Room. Pennsylvania Coalition of Nurse Practitioners State Conference; Nov 2014, Pittsburgh, PA. PRESENTATIONS: QUALITY Kupec C. Operational Excellence – A Multidisciplinary Approach to Achieving Improved Quality and Experience of Care. Global Healthcare Professional Network’s Hospital Value Based Purchasing Summit; Dec 2014; Dallas, TX. Nunemacher K. TeamSTEPPS: From Start up to the Tipping Point! TeamSTEPPS: 2013 National Conference; June 2013; Dallas, TX. Sabol D, Knolle J. Leveraging Employee Recognition Programs to Accelerate Performance Improvement. Concurrent Session Discussion. Premier Conference; June 2011; Nashville, TN.

AWARDS HAP Achievement Awards St. Luke’s University Health Network received four Achievement Awards from the Hospital & Healthsystem Association of Pennsylvania (HAP) in 2014 for its outstanding efforts to improve health care in the state. HAP recognized St. Luke’s in the following categories for the following projects: • Workplace: Emergency Department Safety & Security Project: Visitor Process & Accountability • Patient Safety: A Multifactorial Risk Reduction Strategy for Preventing Perineal Trauma and Increasing Maternal Safety at Vaginal Delivery • Patient Care: A Clinical Nurse Leader Led Multidisciplinary Heart Failure Program: Integrating Best Practice Across the Care Continuum to Reduce Avoidable 30 Day Readmissions • Operational Excellence: The Journey to Hospital Value-Based Purchasing Success FIRST ANNUAL ROBIN HAFF RESEARCH AND SCHOLARSHIP AWARD Toni Marek-Mazzariello, RN, BSN, CCAP, St. Luke’s Hospice VNA: Aromatherapy Treatment for Hospice Patients Experiencing Terminal Restlessness. April 2014.

RESEARCH.SLUHN.ORG | 21

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Investigational Drug Studies – Department of Pharmacy At St. Luke’s University Health Network, the Department of Pharmacy aids investigators and research personnel in the use of medications utilized in clinical trials. The responsibilities of the Pharmacy related to clinical trials include: • Serving as a resource to investigators regarding the development of investigational drug studies. • Obtaining and storing study medication and related supplies. • Screening physician orders and patient information for safe use of study drugs and adherence to study protocols. • Preparing medication according to protocol. • Ensuring that labeling, drug storage, dispensing, and accountability records comply with federal, state and local guidelines. • Maintaining accurate clinical trial medication accountability records. • Meeting with study monitors and regulatory agencies. • Providing information and training about study medications. • Reviewing protocols for the Network’s Institutional Review Board.

Contact Information Pharmacy Department Clinical Trials Coordinator St. Luke’s University Health Network 801 Ostrum Street Bethlehem, PA 18015 484-526-4211 PUBLICATIONS Doshi NM, Cook CH, Mount KL, Stawicki SP, Frazee EN, Personett HA, Schramm GE, Arnold HM, Murphy CV. Adjunctive Aerosolized Colistin for Multi-drug Resistant Gram-negative Pneumonia in the Critically ill: A Retrospective Study. BioMed Central Anesthesiology. Nov 2013; 13(1): 45. doi: 10.1186/14712253-13-45. Reichert J, Hlavinka, P, Stoltzfus, J. Risk of Hemorrhage in Patients with Chronic Liver Disease and Coagulopathy Receiving Pharmacologic Venous Thromboembolism Prophylaxis. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. Oct 2014; 34(10): 1043-1049. doi: 10.1002/phar.1464.

The Department of Pharmacy aids investigators and research personnel in the use of medications utilized in clinical trials.

RESEARCH.SLUHN.ORG | 23

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

St. Luke’s Global Presence Our faculty members are actively involved in promoting health and wellness around the globe. From providing much needed mentorship and surgical care in Cameroon, to educating emergency physicians in India, to participating in surgical mission trips to Ecuador, St. Luke’s physicians are there to help and lead. AMONG THE PHYSICIANS WHO HAVE PARTICIPATED IN INTERNATIONAL PROJECTS ARE: • Dr. Stanislaw P. Stawicki, who serves on the Advisory Board of the Maharishi Markandeshwar University, Mullana, India. He also is a Member of the INDO-US International Advisory Council and participated as an organizer for the annual INDO-US Emergency & Trauma Collaborative Summit since 2012. • Dr. William G. De Long, orthopaedic surgeon, faculty member of the International Orthopedic Trauma Care Forum in 2010 and 2014. • Dr. Marian McDonald, who has completed several independent medical and surgical mission trips to Haiti (Gros Morne and Port au Prince) with both local organizations and a respected international organization. These programs encourage sustainable development in medical care and in-country partners. Her projects include the development of a shortterm, ACGME (Accreditation Council for Graduate Medical Education)-accredited rotation near Port au Prince for St. Luke’s medical students. In addition, Dr. McDonald also completed programs in Costa Rica and Ghana, West Africa. • St. Luke’s surgeons and podiatry specialists participate in various outreach initiatives involving South America.

ST. LUKE’S INTERNATIONAL SURGICAL STUDIES Under the direction of Dr. Richard P. Sharpe, St. Luke’s University Hospital in Bethlehem, PA, has developed the St. Luke’s International Surgical Studies (SLISS) Program. SLISS works to meet the health care needs of populations in developing nations through sustained improvements in care as well as train the next generation of medical professionals to meet the needs of the international community. This program was designed specifically to partner with hospitals in host nations and provide supplies, equipment, training and visiting medical professionals. To accomplish this, SLISS has partnered with Mbingo Baptist Hospital (MBH) in Cameroon, Africa and will assist them in serving their patients. Much needed supplies were shipped and hand carried to MBH. In addition, the SLISS program developed an elective in which fourth year general surgery residents, accompanied by an attending physician from the Division of Trauma and Acute Care Surgery, will have the opportunity to spend one month at MBH. They will be working with MBH residents who are trained through a program administered by the Pan African Academy of Christian Surgeons (PAACS). Residents from St. Luke’s will work side by side with their African counterparts in an ongoing exchange of training and experiences that will be mutually beneficial.

St. Luke’s physicians are there to help and lead.

For the St. Luke’s general surgery residents, the many benefits of their Cameroon elective will include learning how to perform surgery in an austere setting where medical supplies are limited and ancillary support services are non-existent. They will gain experience in diagnosing and treating common conditions that present much later in the course of the disease as well as illnesses unique to the location. They will develop logical and ingenious approaches to manage these patients in a resource limited environment and gain a clearer understanding of the term “Global Surgery” including disparities in the level of care that is available as well as access to that care.

October 2014 was the first rotation at MBH and an excellent start for the SLISS program. Due to this overwhelmingly positive experience, and the strong desire of MBH to have the program continue, additional one-month rotations are planned for the 2015-2016 academic year. The total cost of the trip is $3000 per person and funded solely through donations. For more information on the SLISS program, including photos, videos and daily blogs from the October rotation, please visit the program’s web site: www.sluhn.org/sliss. PUBLICATIONS Kalra S, Kelkar D, Galwankar SC, Papadimos TJ, Stawicki SP, Arquilla B, Hoey BA, Sharpe RP, Sabol D, Jahre JA. The Emergence of Ebola as a Global Health Security Threat: From ‘Lessons Learned’ to Coordinated Multilateral Containment Efforts. Journal of Global Infectious Diseases. Oct 2014; 6(4): 164-77. doi: 10.4103/0974-777X.145247. Swaroop M, Galwankar SC, Stawicki SP, Balakrishnan JM, Worlton T, Tripathi RS, Bahner DP, Bhoi S, Kaide C, Papadimos TJ. The 9th Annual INDUS-EM 2013 Emergency Medicine Summit, “Principles, Practices, and Patients,” a Level One International Meeting, Kerala University of Health Sciences and Jubilee Mission Medical College and Research Institute, Thrissur; Oct 2013; Kerala, India, 2013. Philosophy, Ethics, and Humanities in Medicine. May 2014; 9: 8. doi: 10.1186/1747-5341-9-8.

RESEARCH.SLUHN.ORG | 25

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Medical Textbooks Authored by St. Luke’s Research Faculty Jeanmonod R, Tomassi M, Mayer D, eds. Case Studies in Emergency Medicine. Cambridge: Cambridge University Press; 2010.

Stawicki SP, Galwankar SC, Papadimos TJ, MoffattBruce SD (Editors). Fundamentals of Patient Safety in Medicine and Surgery. Gurgaon, India: Wolters Kluwer Health: 2014.

Textbook Chapters Authored by St. Luke’s Research Faculty Adesanya TM, Sullivan R, Stawicki SP, Evans DC. “Nutrition in Traumatic Brain Injury: Focus on the Immune Modulating Supplements.” In Sadaka F, ed. Traumatic Brain Injury. Rijeka, Croatia: InTech; 2014: 219-248. Airoldi J. Chapter 26: Antiphospholipd Syndrome, Chapter 27: Inherited Thrombophilia, Chapter 28: Venous Thromboembolism and Anticoagulation. In: Berghella V ed. Maternal-Fetal Evidence Based Guidelines. London; Informa Healthcare; 2012: 202-225. Anderson D. Chapter 32: Cancer Epigenetics Cancer Epigenetics. In: Tollefsbo T (eds). Handbook of Epigenetics. London: Elsevier Press: Dec 2010. doi: 10.1016/B978-0-12-375709-8.00032-0.

Brown A. “Traumatic Spinal Cord Injury.” In: Jeanmonod R, Tomassi M, Mayer D, eds. Case Studies in Emergency Medicine. Cambridge: Cambridge University Press; 2010: 203-207. Gale J, Stawicki SP, Swaroop M. Chapter 15: Patientcentered Clinical Transformation: Case Examples. In: Stawicki SP (Chief Editor), Galwankar SC, Papadimos TJ, Moffatt-Bruce SD, eds. Fundamentals of Patient Safety In Medicine and Surgery. Gurgaon, India: Wolters-Kluwer; 2014: 138-146. Jones C, Stawicki SP, Evans DC. Nasoenteric Tube Problems and Enteral Feeding. In: Rajendram R, Patel VB, Preedy VR. Springer, eds. Diet & Nutrition in Critical Care. In press.

Bach JA, King S, Khabiri H, Lindsey DE, Stawicki SP. Superior Vena Cava Filters: A Case-Based Approach. In: Dieter RS ed. Endovascular Interventions: A CaseBased Approach to Methods and Procedures. New York: Springer; 2013: 1003-1011. Brathwaite S, Casabianca AB, Berger JS, Papadimos TJ, Stawicki SP. Chapter 16: Teaching and Fostering Safety Leadership Characteristics. In: Stawicki SP (Chief Editor), Galwankar SC, Papadimos TJ, Moffatt-Bruce SD, eds. Fundamentals of Patient Safety in Medicine and Surgery. Gurgaon, India: Wolters-Kluwer; 2014: 149-162. Brathwaite S, Papadimos TJ, Stawicki SP. Chapter 25: Technology and Patient Safety: Balancing Productivity Gains and Potential Dangers. In: Stawicki SP (Chief Editor), Galwankar SC, Papadimos TJ, Moffatt-Bruce SD, eds. Fundamentals of Patient Safety in Medicine and Surgery. Gurgaon, India: Wolters-Kluwer; 2014: 237-251.

More than 180 fellows, residents and interns train at St. Luke’s, which is one of only 400 members of the prestigious Council of Teaching Hospitals.

Lam NC, Bordelon PC. â&#x20AC;&#x153;Well Adult Exam.â&#x20AC;? In: Ebell MH, Ferenchick G, Smith M, Barry H, Slawson D, Shaughnessy A, Forsch R, Li S, Wilkes M, Usatine R, eds. E-Essential Evidence, 1st ed. Hoboken, NJ: Wiley and Sons, 2009. Langan RC. Ulcerative colitis. In: Ebell MH, Ferenchick G, Smith M, Barry H, Slawson D, Shaughnessy A, Forsch R, Li S, Wilkes M, Usatine R, eds. Essential Evidence. John Wiley & Sons: Hoboken, NJ, 2009. Liang J, DeSimone C, Lachman N, Noheria A, Nanda S, Asirvatham S. Chapter 5: Cardiac Anatomy for Catheter Mapping and Ablation of Arrhythmias. In: Huang S, Miller J, eds. Catheter Ablation of Cardiac Arrhythmias: Third Edition; Canada: Elseiver; 2014: 6. 85-109. Latchana N, Peck JR, Stawicki SP. (2014). Chapter 8: How and Why Things Go Wrong: The Art of Unbiased Understanding. In: Stawicki SP (Chief Editor), Galwankar SC, Papadimos TJ, Moffatt-Bruce SD eds: Fundamentals of Patient Safety in Medicine and Surgery. Gurgaon, India: Wolters-Kluwer; 2014: 74-82. Lisenby E. Uremia and Altered Mental Status. In: Jeanmonod R, Tomassi M, Mayer D, eds. Case Studies in Emergency Medicine. Cambridge: Cambridge University Press; 2010: 407-409. Lux J. Altered Mental Status Due to Hypercarbia. In: Jeanmonod R, Tomassi M, Mayer D, eds. Case Studies in Emergency Medicine. Cambridge: Cambridge University Press; 2010. Matullo K, Dennison D. Acute Fractures, Nonunions, Malunions: Forearm, Hand and Upper Extremity Textbook. ASSH. 2013. Matullo K, Shin A. Chapter 41: ORIF of Scaphoid Fractures. In: Atlas of Essential Orthopaedic Procedures. AAOS. June 2013. Mellon M, De Long WG, Rehman S. Distal Femur Fractures. In: Ilyas, AM, Rehman S, ed. Contemporary Surgical Management of Fractures and Complications. New Delhi, India: Jaypee Brothers Medical Publishing (P) Ltd; March 2013:737-765. Narula VK, Stawicki SP. (2014). Chapter 26: Patient and Family Involvement in Maintaining the Culture of Safety. In: Stawicki SP (Chief Editor), Galwankar SC, Papadimos TJ, MoffattBruce SD, eds. Fundamentals of Patient Safety in Medicine and Surgery. Gurgaon India: Wolters-Kluwer; 2014: 255-260. Papadimos TJ, Gafford E, Stawicki SP. Chapter 21: Empowering Patients and Families: Engagement, Candor, and Disclosure. In: Stawicki SP (Chief Editor), Galwankar SC, Papadimos TJ, Moffatt-Bruce SD, eds. Fundamentals of Patient Safety in Medicine and Surgery. Gurgaon, India: Wolters-Kluwer; 2014: 201-207. Papadimos TJ, Stawicki SP. Chapter 23: Role of Prospective Approaches in Patient Safety and Patient Safety Research. In: Stawicki SP (Chief Editor), Galwankar SC, Papadimos TJ, Moffatt-Bruce SD, eds. Fundamentals of Patient Safety in Medicine and Surgery. Gurgaon, India: Wolters-Kluwer; 2014: 305-312. Stawicki SP, Galwankar SC, Papadimos TJ, Moffatt-Bruce SD. (2014). Chapter 1: History of Iatrogenic Harm: Evolution of Patient Safety and Quality Systems. In: Stawicki SP (Chief Editor), Galwankar SC, Papadimos TJ, Moffatt-Bruce SD, eds. Fundamentals of Patient Safety in Medicine and Surgery. Gurgaon, India: Wolters-Kluwer; 2014: 3-13.

RESEARCH.SLUHN.ORG | 27

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Anesthesiology Approximately 70 anesthesiologists provide medical treatment and surgical procedures for patients at St. Luke’s University Health Network’s six hospital campuses. They include fellowship-trained physicians specializing in critical care, trans-esophageal echocardiography and pain management. St. Luke’s anesthesiologists provide medical treatment and surgical procedures including: epidural injections; cervical, thoracic and lumbosacral nerve root blocks; spinal cord and peripheral nerve stimulation; caudal epidural injections; sacroiliac joint injections; discography; diagnostic medial branch block (cervical/thoracic/ lumbar); cervical, thoracic and lumbar medial branch radiofrequency neurotomy (Rhizotomy); intercostal nerve blocks; occipital nerve blocks; hip joint injections; stellate injections; lumbar sympathetic blocks. Led by Dr. Aldo Carmona, Chief of the SLUHN Department of Anesthesiology and Anesthesiology Faculty Member at Temple University School of Medicine, the department is in the process of developing a perioperative surgical home, a patient-centric approach to the treatment of a patient’s surgical episode from the time a case is scheduled to the post discharge period. To date, a new preadmission process including a geriatric surgery program, enhanced recovery pathways for individual surgery types and acute pain service for the effective treatment of post-operative pain have been instituted. Plans for a post discharge follow-up clinic are currently being developed.

Among other educational efforts, the Department of Anesthesia supports St. Luke’s Critical Care Fellowship Program, a three-year (PGY 1-3) ACGME-approved Emergency Medicine Residency Program providing an academically rigorous curriculum in a tertiary, academic medical center. The fully accredited program exposes residents to a broad spectrum of pathology providing them with experience in managing the breadth of conditions seen in emergency medicine. The St. Luke’s Trauma Fellowship offers both a twoyear Surgical Critical Care Fellowship for emergency medicine graduates, and a one-year fellowship for graduates of surgical programs. In 2012, the fellowship was awarded ACGME (Accreditation Council for Graduate Medical Education) accreditation, and was approved by the American Board of Surgery to include surgical critical care into its curriculum and training. St. Luke’s is one of the first institutions in the country to offer a two-year track for a surgical critical care fellowship for emergency medicine residency graduates approved by the American Board of Surgery.

All anesthesiologists at the Bethlehem Campus have completed either basic or advanced trans-esophageal echocardiography certification. This aids in the rapid diagnosis and treatment of cardiovascular conditions intra- and post-operatively. St. Luke’s Anesthesiology Department is the first department of its size in the nation to achieve this distinction.

Anesthesiologists include fellowship-trained physicians specializing in critical care, trans-esophageal echocardiography and pain management.

PUBLICATIONS & ABSTRACTS Burkey S, Fedor P, Stromski C, Jeanmonod R. Airway Management of the Helmeted Athlete: Direct vs. Assisted Laryngoscopy. MN Journal of Sports Medicine. 2010; 20(2): 147. Pester J, Robinson J, Prestosh J, Roozendaal S, Jeanmonod R. Impact of the United States Propofol Ban on Emergency Providers’ Procedural Sedation Agent Choice and Patient Length of Stay. World Journal of Emergency Medicine. Sept 2012; 3(3): 177-181. doi: 10.5847/ wjem.j.1920-8642.2012.03.003. Stawicki SP, Hoff WS, Cipolla J, DeQuevedo R. Use of Non-invasive Esophageal echo-Doppler System in the ICU: A Practical Experience. Journal of Trauma. Aug 2005; 59(2): 506-507. Stawicki SP, Papadimos TJ. Challenges in Managing Amniotic Fluid Embolism: An Up-todate Perspective on Diagnostic Testing with Focus on Novel Biomarkers and Avenues for Future Research. Current Pharmaceutical Biotechnology. 2014; 14(14): 1168-1178. PRESENTATIONS Genzlinger M, Salen P, Villanueva R, Grossman M, Stoltzfus J. “Put Me Out Doc”: Ketamine Versus Etomidate for the Reduction of Orthopedic Dislocations (“DisloKET”). ACEP Scientific Assembly; Sept 2012; Denver, CO. Milazzo A, Villaneuve R, Salen P, Stoltzfus J, Grossman M, Grossman M. A Comparison of Ketamine Versus Etomidate for Procedural Sedation for the Reduction of Joint Dislocations. ACEP Research Forum; Oct 2014; Chicago, IL. Myers J, Giller C, Kriner R, Anasti JN. The Effect of Abdominal Binder on Pain and Distress in Post Cesarean Section Patients. 62nd Annual Clinical Meeting of the American College of Obstetrians and Gynecologists 2014; April 2014; Chicago, IL. Nunemaker K, Martin M, Anasti JN, Pai A. Building Better Teams Utilizing TeamSTEPPS and E-Learning Technology. Agency for Healthcare Research and Quality; Nov 2013; Washington, DC. Robinson J, Prestosh J, Roozendaal S, Pester J, Jeanmonod R. Impact of the Diprivan Ban on Procedural Sedation Practice and Patient Length of Stay. American College of Osteopathic Emergency Physicians Scientific Assembly; Oct 2012; Denver, CO. Trinidad C, Meyers J, Nunnamaker K, Merola J, Anasti JN. Staff Perceptions of a Culture of Safety: Impact of a Comprehensive OB Patient Safety Program. 61st Annual Clinical Meeting of the American College of Obstetricians and Gynecologists. May 2013; New Orleans, LA.

RESEARCH.SLUHN.ORG | 29

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION 30

Behavioral Health Services St. Luke’s Behavioral Health Services provides a wide variety of mental and behavioral health ranging from stress management to the medical management and treatment of complex conditions such as bi-polar disorder. Among the many innovative services is a specialized Older Adult Behavioral Health Unit which opened in February 2013. A geriatric-trained psychiatrist, a gerontologist, medical-surgical nurses, mental health technicians, case managers and activity therapists staff the unit. In addition to treating the patients’ behavioral health conditions, they also address the medical health concerns that often accompany advanced age, such as diabetes, hypertension and heart disease. In addition, St. Luke’s operates a 23-bed adult inpatient unit at St. Luke’s University Hospital – Bethlehem and a 19-bed unit at St. Luke’s Quakertown Hospital, which

accepts both adults and adolescents. A team of psychiatrists, nurses, social workers, occupational therapists and other mental health experts staff both units. A crisis team, which operates around the clock, serves the hospitals’ emergency rooms. Besides inpatient care, St. Luke’s Behavioral Health Services operates a partial hospitalization day program, as well as individual, group, couples and family therapy. Among the many conditions treated are anxiety disorders, attention deficit disorder, depression, panic disorder, phobias, post-partum depression and post-traumatic stress disorder.

St. Luke’s Behavioral Health Services operates a partial hospitalization day program, as well as individual, group, couples, and family therapy.

PUBLICATIONS & ABSTRACTS Nourse R, Reade C, Stoltzfus J, Mittal V. Demographics, Clinical Characteristics, and Treatment of Aggressive Patients Admitted to the Acute Behavioral Unit of a Community General Hospital: A Prospective Observational Study. http://www.psychiatrist.com/pcc/ abstracts/abstracts.asp? abstract=13m01589/13m01589.htm. Was posted to the Primary Care Companion for CNS Disorders. Nourse R, Reade C. Intervening to Prevent Violence in Psychiatric Units. Nursing. July 2012; 42(7); 14-17. Wisler JR, Springer AN, Hateley K, Mo XM, Evans DC, Cook CH, Gerlach AT, Murphy CV, Eiferman DS, Steinberg SM, Bergese SD, Papadimos TJ, Stawicki SP. Pre-injury Neuropsychiatric Medication Use, Alone or in Combination with Cardiac Medications, May Affect Outcomes in Trauma Patients. Journal of Postgraduate Medicine. 2014; 60(4): 366. PRESENTATIONS Reade C, Nourse R. Demographics, Clinical Characteristics, and Symptoms Severity of Aggressive Patients Admitted to the Acute Behavioral Health Unit of a Community General Hospital: A Prospective Study. American Psychiatric Nursing Association National Conference, October 2013; San Antonio, TX. Reade C, Rosemary Nourse, Co-Author. Implementation of Evidence-Based Discharge Planning Practices to Decrease Psychiatric Readmission Rates. American Psychiatric Nursing Conference; November 2012; Pittsburgh, PA.

RESEARCH.SLUHN.ORG | 31

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Critical Care St. Luke’s University Health Network is prepared to meet the needs of critically ill or injured patients who arrive at any Network hospital. From trauma centers and emergency rooms to operating rooms and intensive care units, patients have access to the latest life-saving technology and critical care specialists. Dr. Robert deQuevedo leads a team of physicians and advanced practitioners who specialize in critical care medicine. St. Luke’s critical care physicians come from several medical specialties such as pulmonary and critical care medicine, traumatology and surgical critical care, anesthesiology and internal medicine. Critical care services at St. Luke’s University Health Network are unified under the Center for Critical Care, a high-performing, clinically integrated organization dedicated to meeting the growing challenges and complexity of modern health care. Medical, surgical, cardiovascular and neuroscience services are pushing the envelope on patient outcomes and practical applications of research. Dr. Livia Bratis is Section Chief of Pulmonary Medicine and Medical Critical Care. Dr. James Cipolla is Section Chief of Emergency Surgery and leads Surgical Critical Care. Dr. deQuevedo also serves as the director of Cardiovascular Critical Care. John Gillard, PA-C, leads the Critical Care Advanced Practitioners. CRITICAL CARE AND MEDICAL EDUCATION St. Luke’s has a long tradition of medical education and research. The faculty is comprised of boardcertified emergency physicians and offers residency programs in internal medicine, general surgery, obstetrics and gynecology, orthopaedics, family practice, podiatry and dentistry. The St. Luke’s Trauma Fellowship offers both a twoyear Surgical Critical Care Fellowship for emergency medicine graduates, and a one-year fellowship for graduates of general surgical programs. In 2012, the fellowship was awarded ACGME (Accreditation Council for Graduate Medical Education) accreditation and was approved by the American Board of Surgery to include surgical critical care into its curriculum and

training. St. Luke’s is one of the first institutions to offer a two-year track for a Surgical Critical Care Fellowship for emergency medicine residency graduates approved by the American Board of Surgery. Dr. James Cipolla and Dr. Marc Portner are the co-directors of the surgical critical care fellowship. Like their physician colleagues, the specialty of critical care for advanced practitioners requires a great deal of post-graduate education. This intensive training is offered via St. Luke’s University Health Network’s 12-month acute care advanced practitioner postgraduate fellowship with tracks in critical care/surgical or emergency medicine/critical care or subspecialty. Six core clinical rotations are the mainstay of the fellowship; followed by specialization in one of the two tracks, allowing fellows to refine their educational experience. St. Luke’s University Health Network is one of only a small number of programs in the United States, and the only in the region, to offer acute care certified registered nurse practitioners and physician assistants this level of comprehensive training. Research has long been an important mission for the critical care team at St. Luke’s University Health Network. PUBLICATIONS Airoldi, James A. MD; McCrosson, Stacy MD; Ness, Amen MD; Sarno, Albert MD; Berghella, Vincenzo MD. The Rate Asymptomatic Intra-amniotic Infection in Women With Differing Degrees of Membrane Prolapse. Obstetrics & Gynecology. April 2006; 4(4): 275-277. doi: 10.4103/2229-5151.147517. Airoldi, J, Laura Greco, Sarah Lopez, Mari Trinidad. The Risk of Asymptomatic Intrauterine Infection Based on Cervical Length and Gestational Age. American Journal of Obstetrics and Gynecology. Jan 2013; 208(1): S218–S219.

From trauma centers and emergency rooms to operating rooms and intensive care units, patients have access to the latest life-saving technology.

Airoldi, James A. MD; Ness, Amen MD; McCrosson, Stacy MD; Carpenter, Pamela; Pereira, Leonardo MD; Berghella, Vincenzo MD. Amniocentesis Before Rescue Cerclage: Does Ruling Out Subclinical Infection Influence Outcome? Obstetrics & Gynecology. April 2006; 104(4): 36S-37S. Cohen MS, Cipriano A, Stawicki SP, Firstenberg MS, Papadimos TJ. Whatâ&#x20AC;&#x2122;s New in Critical Illness and Injury Science: The Decades-long Quest for a Valid Prognostic Sepsis Biomarker Continues. International Journal of Critical Illness & Injury Science. 2014; 4(4): Eiferman DS, Davido HT, Howard JM, Gerckens J, Evans DC, Cook CH, Stawicki SP. Two Methods of Hemodynamic and Volume Assessment in Critically Ill Patients: A Study of Disagreement. Journal of Intensive Care Medicine. April 2014 [Epub ahead of print]. Kent AJ, Bahner DP, Eiferman DS, Boulger CT, Springr A, Adkins EJ, Evans DC, Yeager S, Roelant GJ, Stawicki SP. Bedside Sonographic Assessment of Intravascular Volume Status in the Surgical Intensive Care Unit: Is Subclavian Vein Collapsibility Equivalent to Inferior Vena Cava Collapsibility? Journal of Surgical Research. Jan 2013: 179(2): 271-272. doi: 10.1016/j.jss.2012.10.526. Kwon HP, Zanders TB, Regn DD, Burkett SE, Ward JA, Nguyen R, et al. Comparison of Virtual Bronchoscopy to Fiber-optic Bronchoscopy for Assessment of Inhalation Injury Severity. Burns. 2014; 40(7): 1308-1315. doi: 10.1016/j.burns.2014.06.007. McCrosson, Stacy A. MD; Airoldi, James MD; Nogami, Suzanne; Berghella, Vincenzo MD. The Association of Pregnancy-Specific Risk Factors With Vertical Transmission of Hepatitis C. Obstetrics & Gynecology. April 2006; 107(4): 81S. Mittadodla PS, Kumar S, Smith E, Badireddy M, Turki M, Fioravanti GT. CT Pulmonary Angiography: An Over-utilized Imaging Modality in Hospitalized Patients with Suspected Pulmonary Embolism. Journal of Community Hospital Internal Medicine Perspectives. April 2013; 3(1). doi: 10.3402/jchimp.v3i1.20240. Pappada SM, Cameron BD, Tulman DB, Bourey RE, Borst MJ, Olorunto W, Bergese SD, Evans DC, Stawicki SP, Papadimos TJ. Evaluation of a Model for Glycemic Prediction in Critically Ill Surgical Patients. Public Library of Science One. Jul 2013; 8(7): e69475. doi: 10.1371/journal.pone.0069475.

RESEARCH.SLUHN.ORG | 33

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION 34

Patil P, Kelly N, Papadimos TJ, Bahner DP, Stawicki SP. Correlations Between Venous Collapsibility and Common Hemodynamic and Ventilatory Parameters: A Multivariable Assessment. OPUS 12 Scientist. 2014; 8(1): 1-5. Pester J, Robinson J, Prestosh J, Roozendaal S, Jeanmonod R. Impact of the United States Propofol Ban on Emergency Providers’ Procedural Sedation Agent Choice and Patient Length of Stay. World Journal of Emergency Medicine. Sept 2012; 3(3): 177-181. doi: 10.5847/wjem.j.1920-8642.2012.03.003. Rekuc Emily, Chaya R, Airoldi J. Are There Third Trimester Ultrasound Findings that Could Identify Late Onset Gestational Diabetes? American Journal of Obstetrics and Gynecology. Jan 2011; 204(1): S116–S117.

Stawicki SP, Swaroop M, Galwankar SC, Papadimos TJ. What’s New in Critical Illness and Injury Science? State of the Art in Management of ARDS. International Journal of Critical Illness & Injury Science. April 2014; 4(2): 95-7. doi: 10.4103/2229-5151.134140. Tulman DB, Stawicki SP, Whitson BA, Gupta SC, Tripathi RS, Firstenberg MS, Hayes D, Xu X, Papadimos TJ. Venovenous ECMO: A Synopsis of Nine Key Potential Challenges, Considerations, and Controversies. BioMed Central Anesthesiology. Aug 2014; 14(1): 65. doi: 10.1186/1471-2253-14-65. ABSTRACTS Airoldi J, Berghella V, Sehdev H, Ludmir J. Transvaginal Ultrasonography of the Cervix to Predict Preterm Birth in Women With Uterine Anomalies. Obstetrics & Gynecology. Sept 2005; 106(3): 553-556.

Dentistry To improve dental health throughout the region, St. Luke’s University Health Network offers the Dental Health Initiative and our Dental Residency Program. The Dental Health Initiative provides care for children and adults at our dental health centers in Bethlehem and Easton. A program of the Bethlehem Partnership for a Healthy Community, the Dental Health Initiative is a collaborative effort dedicated to improving the quality of life and health of residents in Bethlehem, Pennsylvania and surrounding areas. The program includes two mobile dental vans, HealthStar I and HealthStar II, which are recreational vehicles outfitted with dental chairs, X-ray and sterilization facilities and a patient waiting area. Working with school nurses, the vans offer comprehensive dental care for children ages 3 to 18 years and are staffed by dentists, dental hygienists and dental assistants. Led by Mohammed O. Qahash, DDS, the St. Luke’s Dental Residency Program offers a comprehensive program, which is accredited by the Commission on Dental Accreditation (CODA). The St. Luke’s Dental Residency Program trains dentists to provide comprehensive primary care to all patients. The program serves a diverse patient population, including older adults and individuals with complex medical conditions and special needs. Clinical experiences include off-service rotations in anesthesiology, emergency medicine, family medicine and community health. Residents will acquire competency in the assessment and treatment of dental and facial trauma, dental emergencies, physical diagnosis and the treatment of office emergencies. PUBLICATIONS Becker W, Wikesjö UM, Sennerby L, Qahash M, Hujoel P, Goldstein M, Turkyilmaz I Histologic Evaluation of Implants Following Flapless and Flapped Surgery: a Study in Canines. Journal of Periodontology. Oct 2006; 77(10): 1717-1722. Huang YH, Polimeni G, Qahash M, Wikesjö UM. Bone Morphogenetic Proteins and Osseointegration: Current Knowledge — Future Possibilities. Periodontology 2000. 2008; 47: 206-23. doi: 10.1111/j.1600-0757.2007.00240.x. Koo KT, Polimeni G, Qahash M, Kim CK, Wikesjö UM. Periodontal Repair in Dogs: Guided Tissue Regeneration Enhances Bone Formation in Sites Implanted with a Coral-derived Calcium Carbonate Biomaterial. Journal of Clinical Periodontology. Jan 2005; 32(1): 104-110. Leknes KN, Yang J, Qahash M, Polimeni G, Susin C, Wikesjö UM. Alveolar Ridge Augmentation Using Implants Coated with Recombinant Human Growth/differentiation Factor-5 (rhGDF-5): Radiographic Observations. Clinical Oral Implants Research. Nov 2013; 24(11): 1185-1191. doi: 10.1111/j.1600-0501.2012.02564.x.

RESEARCH.SLUHN.ORG | 35

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Leknes KN, Yang J, Qahash M, Polimeni G, Susin C, Wikesjö UM. Alveolar Ridge Augmentation Using Implants Coated with Recombinant Human Bone Morphogenetic Protein-2: Radiographic Observations. Clinical Oral Implants Research. Oct 2008; 19(10): 1027-1033. doi: 10.1111/j.1600-0501.2008.01567.x. Leknes KN, Yang J, Qahash M, Polimeni G, Susin C, Wikesjö UM. Alveolar Ridge Augmentation Using Implants Coated with Recombinant Human Bone Morphogenetic Protein-7 (rhBMP-7/rhOP-1): Radiographic Observations. Journal of Clinical Periodontology. Oct 2008; 35(10): 914-919. doi: 10.1111/j.1600-051X.2008.01308.x. Polimeni G, Koo KT, Qahash M, Xiropaidis AV, Albandar JM, Wikesjö UM. Prognostic Factors for Alveolar Regeneration: Bone Formation at Teeth and Titanium Implants. Journal of Clinical Periodontology. Nov 2004; 31(11): 927-932. Polimeni G, Koo KT, Qahash M, Xiropaidis AV, Albandar JM, Wikesjö UM. Prognostic Factors for Alveolar Regeneration: Effect of Tissue Occlusion on Alveolar Bone Regeneration with Guided Tissue Regeneration. Journal of Clinical Periodontology. Sept 2004; 31(9): 730-735.

Polimeni G, Koo KT, Qahash M, Xiropaidis AV, Albandar JM, Wikesjö UM. Prognostic Factors for Alveolar Regeneration: Effect of a Space-providing Biomaterial on Guided Tissue Regeneration. Journal of Clinical Periodontology. Sept 2004; 31(9): 725-729. Polimeni G, Wikesjö UM, Susin C, Qahash M, Shanaman RH, Prasad HS, Rohrer MD, Hall J. Alveolar Ridge Augmentation Using Implants Coated with Recombinant Human Growth/differentiation Factor-5: Histologic Observations. Journal of Clinical Periodontology. Aug 2010; 37(8): 759-68. Qahash M, Hardwick WR, Rohrer MD, Wozney JM, Wikesjö UM. Surface-etching Enhances Titanium Implant Osseointegration in Newly Formed (rhBMP-2induced) and Native Bone. International Journal of Oral Maxillofacial Implants. May-June 2007; 22(3): 472-477. Qahash M, Susin C, Polimeni G, Hall J, Wikesjö UM Bone Healing Dynamics at Buccal Peri-implant Sites. Clinical Oral Implants Research. Feb 2008; 19(2): 166-172. Susin C, Qahash M, Hall J, Sennerby L, Wikesjö UM. Histological and Biomechanical Evaluation of Phosphorylcholine-coated Titanium Implants. Journal of Clinical Periodontology. Mar 2008; 35(3): 270-275. doi: 10.1111/j.1600-051X.2007.01196.x.

Susin C, Qahash M, Polimeni G, Lu PH, Prasad HS, Rohrer MD, Hall J, Wikesjö UM. Alveolar Ridge Augmentation Using Implants Coated with Recombinant Human Bone Morphogenetic Protein-7 (rhBMP-7/rhOP-1): Histological Observations. Journal of Clinical Periodontology. Jun 2010; 37(6): 574-581. doi: 10.1111/j.1600-051X.2010.01554.x. Wikesjö UM, Huang YH, Polimeni G, Qahash M. Bone Morphogenetic Proteins: a Realistic Alternative to Bone Grafting for Alveolar Reconstruction. Oral Maxillofacial Surgery Clinics of North America. Nov 2007; 19(4): 535-51, vi-vii. Wikesjö UM, Polimeni G, Qahash M. Tissue Engineering with Recombinant Human Bone Morphogenetic Protein-2 for Alveolar Augmentation and Oral Implant Osseointegration: Experimental Observations and Clinical Perspectives. Clinical Implant Dentistry and Related Research. 2005; 7(2): 112-119. Wikesjö UM, Qahash M, Huang YH, Xiropaidis A, Polimeni G, Susin C. Bone Morphogenetic Proteins for Periodontal and Alveolar Indications; Biological Observations - Clinical Implications. Orthodontics & Craniofacial Research. Aug 2009; 12(3): 263-270. doi: 10.1111/j.1601-6343.2009.01461.x. Wikesjö UM, Qahash M, Polimeni G, Susin C, Shanaman RH, Rohrer MD, Wozney JM, Hall J. Alveolar Ridge Augmentation Using Implants Coated with Recombinant Human Bone Morphogenetic Protein-2: Histologic Observations. Journal of Clinical Periodontology. Nov 2008; 35(11): 1001-1010. doi: 10.1111/j.1600-051X.2008.01321.x. Wikesjö UM, Qahash M, Thomson RC, Cook AD, Rohrer MD, Wozney JM, Hardwick WR. rhBMP-2 Significantly Enhances Guided Bone Regeneration. Clinical Oral Implants Research. April 2004; 15(2): 194-204. Wikesjö UM, Qahash M, Thomson RC, Cook AD, Rohrer MD, Wozney JM, Hardwick WR. Space-providing Expanded Polytetrafluoroethylene Devices Define Alveolar Augmentation at Dental Implants Induced by Recombinant Human Bone Morphogenetic Protein 2 in an Absorbable Collagen Sponge Carrier. Clinical Implant Dentistry and Related Research. 2003; 5(2): 112-123. Wikesjö UM, Susin C, Qahash M, Polimeni G, Leknes KN, Shanaman RH, Prasad HS, Rohrer MD, Hall J. The Critical-size Supraalveolar Peri-implant Defect Model: Characteristics and Use. Journal of Clinical Periodontology. Nov 2006; 33(11): 846-854. Wikesjö UM, Xiropaidis AV, Qahash M, Lim WH, Sorensen RG, Rohrer MD, Wozney JM, Hall J. Bone Formation at Recombinant Human Bone Morphogenetic Protein-2-coated Titanium Implants in the Posterior Mandible (Type II bone) in Dogs. Journal of Clinical Periodontology. Nov 2008; 35(11): 985-991. doi: 10.1111/j.1600-051X.2008.01318.x. Xiropaidis AV, Qahash M, Lim WH, Shanaman RH, Rohrer MD, Wikesjö UM, Hall J. Boneimplant Contact at Calcium Phosphate-coated and Porous Titanium Oxide (TiUnite)modified Oral Implants. Clinical Oral Implants Research. Oct 2005; 16(5): 532-539.

RESEARCH.SLUHN.ORG | 37

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

ABSTRACTS Koo K-T, Polimeni G, Qahash M, Kim CK, Wikesjö UME. GTR Enhances Bone Regeneration Associated with a Coral Calcium Carbonate Implant. Research forum abstract. American Academy of Periodontology 2002; New Orleans, LA. Polimeni G, Qahash M, Xiropaidis AV, Albandar JM, Wikesjö UME. Vertical Augmentation of Alveolar Bone at Teeth and Dental Implants. Research forum abstract. American Academy of Periodontology; 2002; New Orleans, LA. Qahash M, Wikesjö UM, Thomson RC, Cook AD, Wozney JM, Hardwick WR. Surface-etching Improves Dental Implant Osseointegration in Newly Formed and Native Bone. Journal of Dental Research 2002; 81:IADR-Abstract 4000. Thomson RC, Wikesjö UME, Qahash M, Cook AD, Wozney JM, Hardwick WR. Space-providing Polymer Membranes Act Synergistically with rhBMP-2 to Control the Formation of Induced Alveolar Bone Around Implant Screws. Program abstract. Veterinary Orthopedic Society 29th Annual Conference; 2002; Canyons Ski Resort, UT. Wikesjö UME, Qahash M, Thomson RC, Cook A, Rohrer MD, Wozney JM, Hardwick WR. rhBMP-2 Significantly Enhances GBR at Machined and Surface-etched Dental Implants. Journal of Dental Research 2001; 80:AADR-Abstract 380.

Wikesjö UME, Qahash M, Thomson RC, Cook A, Rohrer MD, Wozney JM, Hardwick WR. Spaceproviding ePTFE Devices Define rhBMP-2 Induced Alveolar Augmentation at Dental Implants. Journal of Dental Research 2001; 80:IADR-Abstract 40. Xiropaidis AV, Qahash M, Lim WH, Shanaman RH, Sorensen RG, Wozney JM, Wikesjö UM, Hall J. Boneimplant Contact at Calcium Phosphate and Titanium Porous Oxide (TiUnite™) Modified Dental Implants. Journal of Dental Research 2002; 81:IADR-Abstract 4001. PRESENTATIONS Qahash M. Effect of Dental Implant Surface Characteristics on Osseointegration in Newly Formed and Native Bone. International Association for Dental Research; 2002; San Diego, CA. Qahash M.rhBMP-2 Significantly Enhances GBR at Machined and Surface- etched Dental Implants. American Association of Dental Research; 2001; Chicago, IL. Qahash M. Space-providing ePTFE Devices Define rhBMP-2 Induced Alveolar Augmentation at Dental Implants. International Association for Dental Research; 2001; Chiba, Japan.

Dermatology St. Luke’s University Health Network is a leader in the treatment of skin conditions. Dermatologists treat a number of conditions including: acne, cellulitis, hair disease, impetigo, psoriasis, vitiligo, skin cancer and melanoma. Dr. Joseph Zaladonis serves as the Section Chief of Dermatology for St. Luke’s University Health Network. The Melanoma Center at St. Luke’s is a regional center of excellence and provides comprehensive care for patients with all stages of the disease. The St. Luke’s team is guided by internationally recognized melanoma expert Dr. Sanjiv Agarwala and board-certified specialists who provide the latest diagnostic and therapeutic care. Caring for skin conditions related to feet is another area of focus. The three-year Podiatric Residency Program helps train experts in podiatric medicine and surgery. Started in 1991 with just a single residency slot, the program has since grown to nine slots because of the increased volume of foot surgery. The program also offers an elective fourth-year slot as a Podiatric Dermatology Fellowship, which was one of the first nationally recognized podiatry fellowships by the Council on Podiatric Medical Education. Our advanced Podiatry Center treats a broad range of podiatric problems, from claw foot to plantar fasciitis and nerve dysfunction. In addition to our busy clinical practice, our faculty and residents are actively involved in a number of high-profile research projects and clinical trials. PUBLICATIONS Agarwala S, Eggermont A, O’Day S, Zager J. Metastatic Melanoma to the Liver: A Contemporary and Comprehensive Review of Surgical, Systemic and Regional Therapeutic Options. Cancer. March 2014; 120(6): 781-789. doi: 10.1002/cncr.28480. Agarwala SS, Guo J, Buzaid AC. Systematic Treatment of Cutaneous and Mucosal Melanoma. Chinese Clinical Oncology. Sept 2014; 3(3): 25. doi: 10.3978/j.issn.23043865.2014.08.07. Agarwala SS. An Update on Pegylated IFN-a2b for the Adjuvant Treatment of Melanoma. Expert Review of Anti-infective Therapy. Nov 2012; 12(11): 1449-1459. doi: 10.1586/era.12.120. Agarwala SS. Intralesional Therapy for Advanced Melanoma: Promise and Limitation. Current Opinion in Oncology. March 2015; 27(2): 151-156. doi: 10.1097/ CCO.0000000000000158. Ascierto P, Schadendorf D, Berking C, Agarwala SS, van Herpen C, Queirolo P, Blank C, Hauschild A, Beck JT, St-Pierre A, Niazi F, Wandel S, Peters M, Zubel A, Dummer R. MEK162 for Patients with Advanced Melanoma Harbouring NRAS or Val600 BRAF Mutations: a Non-Randomised, Open-Label Phase 2 Study. The Lancet Oncology. March 2013; 14(3): 249-256. doi: 10.1016/S1470-2045(13)70024-X.

RESEARCH.SLUHN.ORG | 39

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Bernstein B, Lam H and Motko J. Update on Developing a Comprehensive Diagnostic and Treatment Plan for Charcot Neuroarthropathy – Part I and II. Podiatry Management. January/February 2013. Bernstein B, Ritter Z, Diamond R. Neuropathic Ankle Arthrodesis with Intramedullary Nail Fixation. The Foot and Ankle Online Journal. July 2012; 5(7).

Bernstein B. VAC Therapy with Split Thickness Skin Grafts. Present eLearning, Best Practice in Woundcare. Nov 2013; 1(1).

Buzaid AC, Agarwala SS, Hauschild A, Atkins M. Algorithm for the Management of Metastatic Cutaneous Melanoma. Chinese Clinical Oncology. 2014; 3(3): 32. doi: 10.3978/j.issn.2304-3865.2014.07.01.

Kirsner R, Bernstein B, Bhatia A , Lantis J, Le L, Lincoln K, Liu P, Rogers L , Shaw M, and Young D. Clinical Experience and Best Practices Using Epidermal Grafts, Pending Submitted to: IWJ to Ostomy Wound Management.

Creech CL, Malan JR, Meyr AJ. Evaluation of the Sagittal Saw Blade as an Intraoperative Fomite During Diabetic Foot Surgery. Foot & Ankle Specialist. Nov 2014. pii:1938640014560162.

Leong S, Mihm M, Murphy G, Hoon D, Kashani-Sabet M, Argarwala S, Zager Z, Hauschild A, Sondak V, Guild V, Kirkwood J. Progression of Cutaneous Melanoma: Implications for Treatment. Clinical and Experimental Metastasis. Oct 2012; 29(7):775-796. doi: 10.1007/ s10585-012-9521-1.

Bernstein B, Thuy Vu , Sellers D, PGY-3, Williams A., Lu S. A Retrospective Analysis of Index Events Leading to Acute Charcot Neuroarthropathy. Pending Submission to Diabetologia.

Gabriel A, Shores J, Bernstein B, de Leon J, Kamepalli R, Wolvos T, Baharestani M, Gupta S. A Clinical Review of Infected Wound Treatment with Vacuum Assisted Closure “V.A.C.” Therapy: Experience and Case Studies. International Wound Journal Supplement. Oct 2009; 6(Suppl 2): 1-25. doi: 10.1111/j.1742-481X.2009.00628.x.

Nashan D, Reuter K, Mohr P, Argarwala S. Understanding and Managing Interferon-aRelated Fatigue in Patients with Melanoma. Melanoma Research. Dec 2012; 22(6): 415-423. doi: 10.1097/CMR.0b013e328358d98c. Nemunaitis JJ, Linette GP, Hamid O, Agarwala SS, Starodub A, Sun L, Lebel F, Barrett JA, Lewis J. Regulated Intratumoral Expression of IL-12 as a Basis for Combination Therapy in Melanoma. Journal of Translational Medicine. 2014; 12(Suppl 1): O11. doi: 10.1186/1479-587612-S1-O11. Piraino, JA, Busch EL, Sansosti LE, Pettineo SJ, Creech C. Use of an All-Suture Anchor for Re-Creation of the Anterior Talofibular Ligament: A Case Report. Jan-Feb 2015; 54(1): 126-129. doi: 10.1053/j.jfas.2014.08.020. Rubin AI, Yassaee M, Johnson W, Elenitsas R, Zaladonis J, Seykora JT. Multiple Cutaneous Sclerosing Perineuriomas: An Extensive Presentation with Involvement of the Bilateral upper Extremities. Journal of Cutaneous Pathology. Oct 2009; 36(Suppl 1): 60-65. doi: 10.1111/j.1600-0560.2008.01217.x. Stannard J, Atkins Z, Oâ&#x20AC;&#x2122;Malley D, Singh H, Bernstein B, Fahey M, Masden D, Attinger C, MD. Use of Negative Pressure Therapy on Closed Surgical Incisions: A Case Series. Journal Ostomy and Wound Management. Aug 2009; 55(8): 58-66. Thompson J, Argarwala S, Smithers BM, Ross M, Scoggins C, Coventry B, Neuhaus S, Minor D, Singer J, Wachter E. Phase 2 Study of Intralesional PV-10 in Refractory Metastatic Melanoma. Annals of Surgical Oncology. Oct 2014. doi: 10.1245/s10434-014-4169-5. Wong S, Balch C, Hurley P, Argarwala S, Akhurst T, Cochran A, Cormier J, Gorman M, Kim T, McMasters K, Noyes RD, Lynn M, Schuchter L, Matias E, Valsecchi M, Weaver D, Lyman G. Sentinel Lymph Node Biopsy for Melanoma: American Society of Clinical Oncology and Society of Surgical Oncology Joint Clinical Practice Guideline. Journal of Clinical Oncology. Aug 2012; 30(23): 2912-2918. doi: 10.1200/JCO.2011.40.3519. PRESENTATIONS Bernstein B. Plastic Surgery in Podiatric Medicine. Invited Lecturer. Oklahoma State Podiatric Medical Association Annual Conference; Oct 2012; Oklahoma City, OK. Bernstein B. Sural Artery Flaps. Invited Lecturer. Steelfoot Conference; Oct 2013; Bethlehem, PA. Bernstein B. The Science of Wound Healing and Apligraf. Invited Lecturer. March 2014; Sellerville, PA. Bernstein B. Advisory Panel Presentation on Epidermal Skin Grafting. Symposium on Advanced Wound Care; Oct 2014; Las Vegas, NV. Bernstein B. Epidermal Skin Grafting. Invited Lecturer. Steelfoot 2 Conference; Oct 14; Bethlehem, PA.

RESEARCH.SLUHN.ORG | 41

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION 42

ABSTRACTS Bernstein B, Hawley S. Reverse Sural Artery Pedicle Flap Technique for Heel Ulcer Coverage: A Case Review. Poster. ACFAS Annual Scientific Conference; Feb 2013; Las Vegas, NV. Bernstein B, Joseph E. Class V Sanders Charcot Deformity Revisional Repair of a Complex Calcaneal Fracture: A Case Review. Poster. ACFAS Annual Scientific Conference; Feb 2013; Las Vegas, NV. Bernstein B, Seiler D. Inferior Calcaneal Slide Osteotomy for the Treatment of a Sagittal Plane Dominant Charcot Foot Deformity. Poster. ACFAS Annual Scientific Conference; Feb 2014; Orlando, FL. Bernstein B, Statkewicz M. Improved Split Thickness Graft Take with Negative Pressure Wound Therapy in High-Risk Wounds. Poster. ACFAS Annual Scientific Conference; Feb 2015; Phoenix, AZ.

Bernstein B. Engenex速 Negative-Pressure Wound Therapy System and Its Success in the Treatment of a Diabetic Foot Wound: A Case Study. Poster. Diabetic Limb Salvage Conference; Oct 2010; Washington, D.C. Bronfenbrenner E, Seiler D, Busch E, Bernstein B. Hospital Admissions for Lower Extremity Infections: Comorbidities, Procedures, and Length of Stay. Poster. ACFAS Annual Scientific Conference; Feb 2015; Phoenix, AZ. Malan J, Busch E, Schwartz E. Surgical Management of Flexor Digitorum Accessorieus Longus and Intraretinacular Ganglion Cyst in Multifactorial Tarsal Tunnel Syndrome. Poster. ACFAS Annual Scientific Conference; Feb 2015; Phoenix, AZ. Statkewicz M, Lu S, Williams A , Rocchio T. Advantages of Resorbable Pin Fixation for Metatarsal Osteotomies. Poster. ACFAS Annual Scientific Conference; Feb 2015; Phoenix, AZ.

RESEARCH.SLUHN.ORG | 43

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Emergency Medicine St. Luke’s University Health Network has been providing emergency care since 1872 when it was established to care for the workers of the steel foundries in Bethlehem. Today, it operates Emergency Departments in six hospitals, including a Level 1 Trauma Center – one of only 14 in Pennsylvania. Meanwhile, physicians and other staff members conduct research, present at national conferences, contribute to publications and educate future emergency medicine staff. St. Luke’s Emergency Services stays abreast of advances in emergency medicine to continually improve the quality of services and patient satisfaction. For example, to better serve older adults, the Emergency Department at St. Luke’s – Bethlehem opened a special Older Adult Section that offers a gentler, quieter alternative to the hustle and bustle of the traditional Emergency Department. The St. Luke’s Hospital – Miners Campus was the first hospital in Pennsylvania to achieve designation as a Level IV Trauma Center. The designation is given to hospitals that provide enhanced care to patients within emergency departments with an emphasis on stabilization and transfer to a higher level of care when appropriate. Level IV trauma centers are an enhancement to the larger state-wide trauma system.

Staffed with board-certified emergency care physicians, trained Emergency Department nurses and cuttingedge diagnostic and treatment technology, St. Luke’s Emergency Departments and hospitals offer: • A consistently high level of care for heart attack patients with access to cardiac catheterization laboratories at three hospitals. • Top-performing certified Stroke Centers — a 24-hour emergency response team dedicated to providing specialized stroke care. • A strong team of medical and surgical specialists — including orthopaedic physicians, plastic surgeons, pulmonologists, endocrinologists and infectious disease physicians — working directly with our Emergency Medicine physicians and nurses. EMERGENCY MEDICINE EDUCATION St. Luke’s three-year (PGY 1-3) ACGME-approved Emergency Medicine Residency Program provides an academically rigorous curriculum in a tertiary, academic medical center. The fully accredited program exposes residents to a broad spectrum of pathology, which provides students with experience in managing the breadth of conditions seen in emergency medicine. The Center’s faculty is comprised of board-certified emergency physicians. The St. Luke’s Trauma Fellowship offers both a twoyear Surgical Critical Care Fellowship for Emergency Medicine graduates and a one-year fellowship for graduates of surgical programs. In 2012, the fellowship achieved ACGME (Accreditation Council for Graduate Medical Education) accreditation and was approved by the American Board of Surgery to include Surgical Critical Care into its curriculum and training.

St. Luke’s Emergency Services stays abreast of advances in emergency medicine to continually improve the quality of services and patient satisfaction.

St. Luke’s is one of the first institutions to offer a two-year track for a Surgical Critical Care Fellowship for Emergency Medicine residency graduates approved by the American Board of Surgery. St. Luke’s University Health Network also offers a 12- month acute care advanced practitioner postgraduate fellowship with tracks in emergency medicine/critical care or critical care/surgical subspecialty. Six core clinical rotations are the mainstay of the fellowship, which are then followed by specialization in one of the two tracks. This enables fellows to refine their educational experience. PUBLICATIONS Adesina A, Jeanmonod R. Symptomatic Phytobezoar Presenting 5 Years After Lasprascopic Roux-en-Y Gastric Bypass. Clinical Medical Reviews and Case Reports. Nov 2014; 1(2): 9. Adesina A, Rammohan G, Jeanmonod R. “Retrograde Gastro-jejunostomy Tube Migration. Case Reports in Emergency Medicine. Dec 2014; 2014:738506. doi: 10.1155/2014/738506. Balakrishnan V, Jeanmonod R. Two Episodes of Ventriculoperitoneal Shunt Migration in a Patient with Idiopathic Intracranial Hypertension. Case Reports in Emergency Medicine. 2014; 2014: 280793. doi: 10.1155/2014/280793. Barcomb T, Pattee J, Jeanmonod R. View of Precepting Medical Students by Emergency Medicine Residents. Education in Medicine Journal. June 2012; 4(1). doi:10.5959/eimj.v4i1.12. Buckley RG, Stehman CR, Dos Santos FL, Riffenburgh RH, Swenson A, Mjos N, Brewer M, Mulligan S. Bedside Method to Estimate Actual Body Weight in the Emergency Department. Journal of Emergency Medicine. Jan 2012; 42(1): 100-4. doi: 10.1016/j.jemermed.2010.10.022. Cross D, Matullo KS. Concomitant Endoscopic Carpal and Cubital Tunnel Release: Safety and Efficacy. Hand (NY). March 2014; 9(1): 43-47. doi: 10.1007/s11552-013-9552-3. DelCollo J; Jeanmonod D; Dombchewsky O; Reiter M; Jeanmonod RA. Comparison of Resident and Mid-level Provider Productivity and Patient Satisfaction in an Emergency Department Fast Track. Emergency Medicine Journal. Jan 2013; 30(1):e12. doi: 10.1136/ emermed-2011-200572.

RESEARCH.SLUHN.ORG | 45

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Elison B, Evans D, Jeanmonod R. Persistent Left Superior Vena Cava Draining into the Pulmonary Venous System Discovered After Central Venous Catheter Placement. The American Journal of Emergency Medicine. Aug 2014; 32(8): 943.e1-3. doi: 10.1016/j.ajem.2013.12.042. Evans D, Jeanmonod R, Luizza A, Zanders T. An 85-year-old Male with Dysphagia and Esophageal Perforation from an Anterior, Cervical Osteoarthritic Osteophyte; A Case. American Journal of Emergency Medicine. Nov 2013; doi: 10.1016/j.ajem.2013.11.025. Finan M, Eberhardt M, Jeanmonod R. An Unusual Case of Ventriculoperitoneal Shunt Fracture Caused by Central Line Placement. American Journal of Emergency Medicine. in press. Geer W, Jeanmonod R. Early Presentation of Buried Bumper Syndrome. Western Journal of Emergency Medicine. Sept 2013; 14(5): 421-423. doi: 10.5811/ westjem.2013.2.15843. Goodbred A, Waninger K, Vanic K, Hauth J, Onia J, Stoltzfus J, Melanson S. Adequate Performance of Cardiopulmonary Resuscitation Techniques During Simulated Cardiac Arrest. Clinical Journal of Sports Medicine. 2012; 22(2): 192-193. Habeeb K, Jeanmonod R. Extensive Retroperitoneal Air, Pneumomediastinum and Subcutaneous Air Secondary to Stercoral Perforation. The American Journal of Emergency Medicine. Feb 2014; 32(2): 193. e3-4. doi: 10.1016/j.ajem.2013.09.002. Hamden K, Agresti D, Jeanmonod R, Woods D, Reiter M, Jeanmonod D. Characteristics of Elderly Fall Patients with Baseline Mental Status: High-risk Features for Intracranial Injury. The American Journal of Emergency Medicine. Aug 2014; 32(8): 890-894. doi: 10.1016/j.ajem.2014.04.051. Hamden K, Jeanmonod D, Gualtieri D, Jeanmonod R. A Comparison of Resident and Mid-level Provider Productivity in a High Acuity Emergency Department Setting. Emergency Medicine Journal. March 2014; 31(3): 216-219. doi: 10.1136/emermed-2012-201904.

Hamden K, Pester J, Agresti D, Jeanmonod R, Jeanmonod D. NEXUS in the Alert, Elderly Fall Patient. Annals of Emergency Medicine. Oct 2013; 62(4): S31. doi: 10.1016/j.annemergmed.2013.07.365.

Jeanmonod D, Jeanmonod R. Acute Aortic Occlusion in a Middle-aged Woman with Gastroenteritis. Clinical Medical Reviews and Case Reports. Accepted for publication November 2014. Jeanmonod R, Jeanmonod, D, Cobb T. The Impact of Working with Medical Students on Resident Productivity in the Emergency Department. Western Journal of Emergency Medicine. Nov 2013; 14(6): 585â&#x20AC;&#x201C;589. Jeanmonod R, Katz B. Error Reporting in the Emergency Department: Do We Do What We Say We Do? World Journal of Emergency Medicine. 2012; 3(4): 261-264. doi: 10.5847/wjem.j.1920-8642.2012.04.004.

Jeanmonod R. Lessons on Burnout. Annals of Emergency Medicine. April 2012; 59(4): 327. doi: 10.1016/j.annemergmed.2011.09.008 Jeanmonod R. Spiders. Annals of Emergency Medicine. June 2012; 59(6): 548. doi: 10.1016/j. annemergmed.2011.10.009. Jeanmonod R. What Itâ&#x20AC;&#x2122;s Like? Annals of Emergency Medicine. Sept 2012; 60(3): 391. doi: 10.1016/j. annemergmed.2012.04.002. Kropf J, Jeanmonod R. An Unusual Presentation of a Chronic Ingested Foreign Body in an Adult. Journal of Emergency Medicine. Jan 2013; 44(1):82-84. doi: 10.1016/j.jemermed.2011.06.061. Meyer C, Woolley W, Jeanmonod R, Stern M, Jeanmonod D. How Reliable are Patient Completed Medication Reconciliation Forms Compared to Pharmacy Lists? The American Journal of Emergency Medicine. Sept 2012; 30(7): 1048-1054. doi: 10.1016/j. ajem.2011.06.038. Mittadodla P, Salen P, Traub D. Isoproterenol as an Adjunct for Treatment of Idiopathic VF Storm in a Pregnant Woman. The American Journal of Emergency Medicine. Jan 2012; 30(1): 251. Morrison J, Jeanmonod R. Imaging of the NEXUSnegative Patient: When We Break the Rule. American Journal of Emergency Medicine. Jan 2014; 32(1): 67-70. doi: 10.1016/j.ajem.2013.08.062.

Morrison J, Zweitzig D, Riccardello N, Rubino J, Axelband J, Sodowich B, Kopnitsky M, O’Hara SM, Jeanmonod R. Analysis of Clinical Data from a Molecular Diagnostic Feasibility Study Highlights the Utility for Rapid Blood Stream Infection Detection. The American Journal of Emergency Medicine. 2014: 32(6): 511-516. doi: 10.1016/j. ajem.2014.01.046. Nelson D, Jeanmonod R. Bezold Abscess: A Rare Complication of Mastoiditis. The American Journal of Emergency Medicine. Nov 2013; 31(11): 1626.e3-4. doi: 10.1016/j. ajem.2013.06.036. Nelson D, Jeanmonod R. Randomized Trial of Tourniquet vs Blood Pressure Cuff for Target Vein Dilation in Ultrasound-Guided Peripheral IV Access. The American Journal of Emergency Medicine. July 2014; 32(7): 761-764. doi: 10.1016/j.ajem.2014.04.020. Nelson D, Washton D, Jeanmonod R. Communication Gaps in Nursing Home Transfers to the ED: Impact on Turnaround Time, Disposition, and Diagnostic Testing. American Journal of Emergency Medicine. April 2013; 31(4): 712-716. doi: 10.1016/j.ajem.2012.11.024. Pester J, Robinson J, Prestosh J, Roozendaal S, Jeanmonod R. Impact of the United States Propofol Ban on Emergency Providers’ Procedural Sedation Agent Choice and Patient Length of Stay. World Journal of Emergency Medicine. Sept 2012; 3(3): 177-181. doi: 10.5847/ wjem.j.1920-8642.2012.03.003. Plaster M, Reiter M. 11 Benchmarks That Should Matter to EPs. Emergency Physicians Monthly. January; 2012; 19(1). Reiter M. Emergency Medicine: The Good, The Bad, and the Ugly. Medscape Medical Students. Published on www.medscape.com. Sept 2011. Silberman M, Jeanmonod D, Hamden K, Reiter M, Jeanmonod R. Mid-level Providers Working in a Low-acuity Area are More Productive than When Working in a High-acuity Area. Western Journal of Emergency Medicine. Nov 2013; 14(6): 598–601. doi: 10.5811/ westjem.2012.12.12848.

RESEARCH.SLUHN.ORG | 47

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Silberman M, Jeanmonod R. Aero-digestive Tract Burn from Ingestion of Microwaved Food. Case Reports in Emergency Medicine. 2013; 2013: 781809. doi: 10.1155/2013/781809. Thom CD, Sparks SE. Acute Pediatric Stroke - What’s the Hurry? A Case for Emergency Physician Performed Echocardiography. The American Journal of Emergency Medicine. 2014; 32(11): 1440.e3 - 1440.e5. doi: http:// dx.doi.org/10.1016/j.ajem.2014.04.023. Published online April 16, 2014. Wheeler G, Kropf J, Jeanmonod R. Vasculitis Presenting with Myocardial Infarction, Stroke, and Aortitis in a Middle-aged Man. Journal of Emergency Medicine. Oct 2012; 43(4): 655-658. doi: 10.1016/j. jemermed.2010.05.036. Zweitzig DR, Riccardello NM, Morrison J, Rubino J, Axelband J, Jeanmonod R, Sodowich BI, Kopnitsky MJ, O’Hara SM. Measurement of Microbial DNA Polymerase Activity Enables Detection and Growth Monitoring of Microbes from Clinical Blood Cultures. PLoS One. Oct 2013; 8(10): e78488. doi: 10.1371/journal. pone.0078488. Zweitzig DR, Riccardello NM, Pester JM, Jeanmonod R, Kopnitsky MJ, O’Hara SM. A Novel Approach for Rapid Detection of Bacterially Contaminated Platelet Concentrates Via Sensitive Measurement of Microbial DNA Polymerase Activity. Transfusion. June 2014; 54(6): 1642-51. doi: 10.1111/trf.12487.

PRESENTATIONS Balakarishnan V, Hart R. Looks Gassy: Pneumobilia Status Post Hydrogen Peroxide Ingestion. FOEM Case Study. Poster Presentation. The American College of Osteopathic Emergency Physicians Conference; May 2014; Scottsdale, AZ. Cross D. Cerebral Air Embolism, Stroke and Status Epilepticus Following Peripheral Insertion of Central Catheter: A Case Report. FOEM Case Study. Poster. The American College of Osteopathic Emergency Physicians Conference; May 2014; Scottsdale, AZ. Finan M, Evans D, Balakrishnan V, Jeanmonod D, Cross D, Biornstad R, Pester J, Jeanmonod R. Resuscitative Experience Gained by Emergency Medicine Residents as Rapid Response Team Members. Poster. New England Society for Academic Emergency Medicine Regional Conference; March 2014; New Haven, CT. Finan M, Evans D, Balakrishnan V, Jeanmonod D, Cross D, Biornstad R, Pester J, Jeanmonod R. Elevated Modified Early Warning Score is Rarely Present in Patients Requiring Rapid Response Team Activation. Society for Academic Emergency Medicine MidAtlantic Regional Meeting; Feb 2014; Philadelphia, PA. Finan M, Hahn D, Eberhardt M. How Well are We Using Well’s? St. Luke’s Research Forum; June 2014; Bethlehem, PA. Finan M, Hahn D, Stoltzfus J, Eberhardt M. How Well Do Academic and Community ED Physicians Follow Decision Rules for Pulmonary Embolism? The American College of Emergency Physicians Research Forum; Oct 28, 2014; Chicago, IL. Finan M, Jeanmonod R. The Impact of Standardized Testing on Interview Scoring and Emergency Medicine Applicants’ Rank Position. Presentation # 182 Poster. Society for Academic Emergency Medicine 2013 Annual Meeting; May 14-18, 2013; Atlanta, Georgia. Finan M, Jeanmonod R. Backstage at the Emergency Medicine Match. Poster. 2014 Council for Emergency Medicine Residency Directors Academic Assembly Advances in Education Research and Innovations Forum; March 2014; New Orleans, LA.

Guerrieri E, Hart R, Axelband J, Bendas C, Onia J, Pester J. Use of High Fidelity Simulation to Assess Patient Presentation Skills by PGY1 Emergency Medicine Residents. American College of Osteopathic Emergency Physicians Scientific Assembly; Oct 2013; San Diego, CA. Habeeb K, Axelband J, Stoltzfus J. Incoming Resident Perception of Competency and Knowledge Base of Basic Medical Procedure Enhanced by Procedural Workshop and Educational Material. St. Luke’s Research Forum; June 2014; Bethlehem, PA. Hamden K, Pester J, Agresti D, Jeanmonod R, Jeanmonod D. NEXUS in the Alert Elderly Fall Patient. American College of Emergency Physicians Scientific Assembly; Oct 2013; Seattle, WA. Joseph L, Jeanmonod D, Jeanmonod R. A Comparison of Ultrasound-guided and Palpation-guided Identification of Lumbar Puncture Needle Entry Site in Patients as Body Mass Index Increases. St. Luke’s Research Conference; June 2014; Bethlehem, PA. Kadish J, Layng E, Berrios M, Pester J. STABCric: Surgical Technique Against Bougie Cricothyrotomy. American College of Osteopathic Emergency Physicians Scientific Assembly; Oct 2014; Las Vegas, NV. Kadish J, Salen P, Genzlinger M, Stoltzfus J, Grossman M. An Exploratory Study Comparing Ketamine v. Etomidate for Rapid Sequence Intubation in Traumatically Injured Patients. The American College of Emergency Physicians Scientific Assembly; Oct 2013; Seattle,WA. Loffredo D, Salen P, Guerrieri E, Stoltzfus J. Parenteral V. Oral Phytonadione Administration For Coumadin Induced Coagulopathy. The American College of Emergency Physicians Scientific Assembly; Oct 2013; Seattle, WA. Milazzo A, Villaneuve R, Salen P, Stoltzfus J, Grossman M, Grossman M. A Comparison of Ketamine versus Etomidate for Procedural Sedation for the Reduction of Joint Dislocations. The American College of Emergency Physicians Research Forum; Oct 2014; Chicago, IL. Morrison J, Jeanmonod R. Imaging of the NEXUS-negative Patient: When We Break the Rule. Presentation # 131 Oral Presentation. Society for Academic Emergency Medicine 2013 Annual Meeting; May 2013; Atlanta, Georgia. Nelson L, Nelson D, Stankewicz H. Laceration Length Estimation by Emergency Medicine Providers. St. Luke’s Research Forum; June 2014; Bethlehem, PA. Pester J, Jeanmonod R, Jeanmonod D. Predictors of Traumatic Intracranial Injury in Elderly Fall Patients Meeting Trauma Alert Criteria. St. Luke’s University Health Network Research Forum June 2013. American College of Emergency Physicians Scientific Assembly. Oct 2013; Seattle, WA. Weller K, Jeanmonod R. Retrospective Validation of High Yield Criteria for Obtaining Chest X-ray in Non-traumatic Chest Pain. Presentation # 631 Poster. Society for Academic Emergency Medicine 2013 Annual Meeting; May 2013; Atlanta, Georgia. Wilson J, Jeanmonod R, Cipolla J. To Squeeze or Not to Squeeze? St. Luke’s University Health Network Research Forum; June 2013; Bethlehem, PA.

RESEARCH.SLUHN.ORG | 49

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

ABSTRACT PUBLICATIONS AND PRESENTATIONS Agresti D, Jeanmonod R, Agresti K, Jeanmonod D. Anti-platelet and Anti-coagulant Use Increases Rates of Intracranial Injury In Elderly Patients Presenting to the Emergency Department After a Fall. Poster. Pennsylvania Chapter of the American College of Emergency Physicians; 2012; Gettysburg, PA. Agresti D, Jeanmonod R, Agresti K, Jeanmonod D. Does Starting Position of Fall Predict Significant Head or Neck Injury in the Elderly Patient? Poster. Society for Academic Emergency Medicine; 2012; Chicago, IL. Agresti D, Jeanmonod R. Anti-platelet and Anticoagulants Do Not Increase Traumatic Intracranial Bleeds in Elderly Fall Victims. Oral. # 58. Society for Academic Emergency Medicine 2013 Annual Meeting; May 2013; Atlanta, GA. Agresti D, Jeanmonod R. Derivation Of A Decision Rule For Obtaining a Head CT in the Elderly Fall Patient with Baseline Mental Status. Oral. Society for Academic Emergency Medicine; 2013 Annual Meeting; May 2013; Atlanta, GA. Balakarishnan V, Hart R. Looks Gassy: Pneumobilia Status Post Hydrogen Peroxide Ingestion. FOEM Case Study. The American College of Osteopathic Emergency Physicians Conference; May 2014; Scottsdale, AZ. Bendas C, Roozendaal S, Stockton P, Patterson J. Incidence of Self-Reported Drug Allergies in a Population Identified with Drug-Seeking Behavior. American College of Emergency Physicians Scientific Assembly; Oct 2012; Denver, CO. Cossey K, Jeanmonod R. Impact of Language Discordance on Door-to-Room Time and Patient Satisfaction in Triage. Poster. American College of Emergency Physicians Scientific Assembly; 2012; Denver, CO. Cross D. Cerebral Air Embolism, Stroke and Status Epilepticus Following Peripheral Insertion of Central Catheter: A Case Report. FOEM Case Study. The American College of Osteopathic Emergency Physicians Conference; May 2014; Scottsdale, AZ. DeVader T, DeVader S, Jeanmonod R. Reducing Costs at the End of Life by Initiating Transfer to Inpatient Hospice in the Emergency Department. Poster. American College of Emergency Physicians Scientific Assembly; Sept 2012; Denver, CO.

DeVader T, DeVader S, Jeanmonod R. Saving More than Money: Comparison of ED- Versus Hospital-initiated Transfers to Hospice. Poster. American College of Emergency Physicians Scientific Assembly; 2012; Denver, CO. DeVader T, Jeanmonod R. Does Providing Palliative Care in the Emergency Department Lead to Prolonged Length-of-Stays? American College of Emergency Physicians Scientific Assembly; Sept 2012; Denver, CO. Evans D, Jeanmonod D, Pester J, Jeanmonod R. Nexus in the Elderly Fall Patient: What is Distracting? Poster. Society for Academic Emergency Medicine 2014 Annual Meeting; May 2014; Dallas, TX. Finan M, Evans D, Balakrishnan V, Jeanmonod D, Cross D, Biornstad R, Pester J, Jeanmonod R. Resuscitative Experience Gained by Emergency Medicine Residents as Rapid Response Team Members. Poster. New England Society for Academic Emergency Medicine Regional Conference (NERDS); March 2014; New Haven, CT. Finan M, Evans D, Balakrishnan V, Jeanmonod D, Cross D, Biornstad R, Pester J, Jeanmonod R. Elevated Modified Early Warning Score is Rarely Present in Patients Requiring Rapid Response Team Activation. Society for Academic Emergency Medicine MidAtlantic Regional Meeting. Feb 2014; Philadelphia, PA. Finan M, Hahn D, Eberhardt M. How Well are We Using Well’s? St. Luke’s Research Forum; June 2014; Bethlehem, PA. Finan M, Hahn D, Stoltzfus J, Eberhardt M. How Well Do Academic and Community ED Physicians Follow Decision Rules for Pulmonary Embolism? The American College of Emergency Physicians Research Forum; Oct 2014; Chicago, IL. Finan M, Jeanmonod R, Melanson S. The Impact of Standardized Testing and Interview Scoring on Emergency Medicine Applicants’ Rank Position. Oral. St. Luke’s University Health Network Research Forum; June 2013; Bethlehem, PA. Finan M, Jeanmonod R. Backstage at the Emergency Medicine Match. Poster Presentation. 2014 Council for Emergency Medicine Residency Directors Academic Assembly Advances in Education Research and Innovations Forum; March 2014; New Orleans, LA.

Finan M, Jeanmonod R. The Impact of Standardized Testing on Interview Scoring and Emergency Medicine Applicants’ Rank Position. Poster. # 182. Society for Academic Emergency Medicine 2013 Annual Meeting; May 2013; Atlanta, GA. Genzlinger M, Salen P, Villanueva R, Grossman M, Stoltzfus J. “Put me out Doc”: Ketamine versus Etomidate for the Reduction of Orthopedic Dislocations (“DisloKET”). Poster. The American College of Emergency Physicians Scientific Assembly; Sept 2012; Denver, CO. Genzlinger MA, Eberhardt M. Analyzing Prominent T Waves and ST-segment Abnormalities in Acute Myocardial Infarction. Journal of Emergency Medicine. Aug 2012; 43(2): e81-85. doi: 10.1016/j.jemermed.2009.08.032. Goodbred A, Waninger K, Vanic K, Hauth J, Onia J, Stoltzfus J,Melanson S. Adequate Performance of Cardiopulmonary Resuscitation Techniques During Simulated Cardiac Arrest. American Medical Society of Sports Medicine Annual Meeting; April 2012; Atlanta, GA. Guerrieri E, Hart R, Axelband J, Bendas C, Onia J, Pester J. Use of High Fidelity Simulation to Assess Patient Presentation Skills by PGY1 Emergency Medicine Residents. Poster. American College of Osteopathic Emergency Physicians Scientific Assembly; Oct 2013; San Diego, CA. Habeeb K, Axelband J, Stoltzfus J, Prestosh J, Melanson S. Incoming Resident Perception of Competency and Knowledge Base of Basic Medical Procedures Enhanced by Procedural Workshop and Educational Material. Oral. American College of Osteopathic Emergency Medicine; Oct 2013; San Diego, CA. Hamden K, Agresti D, Jeanmonod R, Jeanmonod D. Derivation of a Decision Rule for Obtaining a Head CT in the Elderly Fall Patient with Baseline Mental Status. Poster. St. Luke’s University Health Network Research Forum; June 2013; Bethlehem, PA. Hamden K, Jeanmonod R. Cervical Spine Injuries In Elderly Fall Patients Who Do Not Meet Trauma Alert Criteria. Presentation # 502. Oral. Society for Academic Emergency Medicine 2013 Annual Meeting; May 2013; Atlanta, GA. Hamden K, Jeanmonod R. Elderly Falls On Level Ground: A Descriptive Study. Oral. Society for Academic Emergency Medicine 2013 Annual Meeting; May 2013; Atlanta, GA. Hamden K, Pester J, Agresti D, Jeanmonod R, Jeanmonod D. NEXUS in the Alert Elderly Fall Patient. Poster. American College of Emergency Physicians Scientific Assembly. Oct 2013; Seattle, WA. Hamden K, Silberman M, Reiter M, Jeanmonod D, Jeanmonod R. Mid-Level Providers Working in a Low-Acuity Area are More Productive than When Working in a High-Acuity Area. Poster. St. Luke’s University Health Network Research Conference; June 2012; Bethlehem, PA. Jeanmonod R, Pester J, Jeanmonod D. Face Trauma as a Predictor of Cervical Spine Injury in Elderly Fall Patients Who Meet Trauma Alert Criteria. Annals of Emergency Medicine. 2013; 62(4): S65-S66. doi: 10.1016/j.annemergmed.2013.07.463. Poster. American College of Emergency Physicians Scientific Assembly; Oct 2013; Seattle, WA.

RESEARCH.SLUHN.ORG | 51

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION 52

Joseph L, Jeanmonod D, Jeanmonod R. A Comparison of Ultrasound-guided and Palpation-guided Identification of Lumbar Puncture Needle Entry Site in Patients as Body Mass Index Increases. St. Luke’s Research Conference; June 2014; Bethlehem, PA. Kadish J, Layng E, Berrios M, Pester J. STABCric: Surgical Technique Against Bougie Cricothyrotomy. Poster. American College of Osteopathic Emergency Physicians Scientific Assembly; Oct 2014; Las Vegas, NV. Krebs E, Kohut S, Salen P. A Simple, Highly Effective Emergency Department Based Pediatric Head Injury Prevention Initiative to Increase Long-Term Bicycle Helmet Use: Free Helmet Distribution Plus Education. Poster. St. Luke’s University Health Network Research Conference; 2012; Bethlehem, PA. Kropf J, Grossman M; Salen P, Genzlinger M, Stehly C, Stoltzfus J, Carmona A. Ketamine vs. Etomidate for RSI in Traumatically Injured Patients: An Exploratory Study. Oral. The American College of Emergency Physicians Scientific Assembly; Sept 2012; Denver, CO. Milazzo A, Villaneuve R, Salen P, Stoltzfus J, Grossman M, Grossman M. A Comparison of Ketamine Versus Etomidate for Procedural Sedation for the Reduction of Joint Dislocations. Poster. The American College of Emergency Physicians Research Forum; Oct 2014; Chicago, IL.

Nelson D, Washton D, Jeanmonod R. Communication Gaps in Transitions in Care in Nursing Home Patients Transferred to the Emergency Department: Impact on Diagnostic Testing. Poster. Pennsylvania Chapter of the American College of Emergency Physicians Regional Scientific Assembly; 2013; Pittsburgh, PA. Nelson L, Nelson D, Stankewicz H. Laceration Length Estimation by Emergency Medicine Providers. St. Luke’s Research Forum; June 2014; Bethlehem, PA. Newsom C, Weller K, Jeanmonod R, Jeanmonod D. CXR Yield in Patients with Isolated Chest Pain: Derivation of a Decision Rule. Oral. St. Luke’s University Health Network Research Forum; June 2013; Bethlehem, PA. Pester J, Jeanmonod D, Jeanmonod R. Application of a Head CT Decision Rule in Elderly Fall Patients with Baseline Mental Status Triaged to the Trauma Bay. Annals of Emergency Medicine. 2013; 62(4): S68-S69. doi: 10.1016/j.annemergmed.2013.07.472. Poster. American College of Emergency Physicians Scientific Assembly; Oct 2013; Seattle, WA. Pester J, Jeanmonod R, Jeanmonod D. Predictors of Traumatic Intracranial Injury in Elderly Fall Patients Meeting Trauma Alert Criteria. Annals of Emergency Medicine. Oct 2013; 62(4): S68. doi: 10.1016/j. annemergmed.2013.07.470.

Morrison J, Jeanmonod R. Utilization of NEXUS C-spine Criteria Among Clinicians in a Community Emergency Department Setting. Poster. American College of Emergency Physicians Scientific Assembly; 2012; Denver, CO.

Pester J, Robinson J, Prestosh J, Roozendaal S, Jeanmonod R. Impact of the United States Propofol Ban on Emergency Providers’ Procedural Sedation Agent Choice and Patient Length of Stay. American College of Osteopathic Emergency Physicians Scientific Assembly; Oct 2012. Denver, CO.

Morrison J, Rubino J, Jeanmonod R, O’Hara SM. Clinical Feasibility of an Improved Blood Culture Assay Enabling Universal Detection of Viable BSI Hematopathogens. Poster. St. Luke’s University Health Network Research Conference; June 2012; Bethlehem, PA.

Robinson J, Prestosh J, Roozendaal S, Pester J, Jeanmonod R. Impact of the Diprivan Ban on Procedural Sedation Practice and Patient Length of Stay. American College of Osteopathic Emergency Physicians Scientific Assembly; Oct 2012; Denver, CO.

Nelson D, Jeanmonod R, Jeanmonod D. Randomized Comparison Trial of Tourniquet Versus Blood Pressure Cuff for Ultrasound-guided Peripheral Intravenous Access. AAEM Scientific Assembly; 2014; New York, NY.

Roper J, Melanson S, Jeanmonod R. Emergency Medicine Applicant Interview Scoring: Can a Global Visual Analog Scale Produce Reliable Results? Poster. American College of Emergency Physicians Scientific Assembly; Sept 2012; Denver, CO.

Rubino J, Morrison J, Zweitzig D, Riccardello N, Sodowich B, Axelband J, Jeanmonod R, Kopnitsky M, O’Hara SM. Preliminary Clinical Feasibility of an Improved Blood Culture Time to Detection Using a Novel Viability Protein Linked PCR Assay Enabling Universal Detection of Viable BSI Hematopathogens 3-fold Earlier than the Gold Standard. Oral. Society for Academic Emergency Medicine; 2012; Chicago, IL. Silberman M, Jeanmonod R. Nursing Treatment Protocols and Physician Order Preference in Chest Pain Patients. Poster. AAEM Scientific Assembly. 2014; New York, NY. Smith T, Eberhardt M. A Comparison of Confirmed Intrauterine Pregnancy by Ultrasound In Patients with Vaginal Bleeding in Early Pregnancy with HCG levels Above and Below 2000. Poster. #232. The American College of Emergency Physicians Scientific Assembly; Oct 2013; Seattle, WA. Taggart B, Wilson J, Cippolla J, Jeanmonod R. Lactate Levels in the Acutely Ill Patient: Does the Tourniquet Falsely Elevate the Result? Abstract in Journal of Emergency Medicine. Accepted January 2013. Oral. AAEM; Feb 2014; New York, NY. Ulitsky A, Jeanmonod R, Agresti D, Agresti K, Jeanmonod D. When Elders Fall: Indications for Antiplatelet Agents and Anticoagulants in Elders who Fall and the Incidence of Fall Recidivism. American College of Emergency Physicians Scientific Assembly; 2012; Denver, CO. Vitto MJ, Sparks SE, Evans DP, Byars DV. A Low Cost, High Fidelity Ultrasound Model for Nerve Block. Society for Academic Medicine - Mid Atlantic Conference. Feb 2014; Philadelphia, PA. Vitto MJ, Sparks SE, Evans DP, Byars DV. A Low Cost, High Fidelity Ultrasound Model for Nerve Block. Critical Ultrasound Journal. Aug 2014; 6(1):12. doi: 10.1186/s13089-014-0012-2. Washton D, Jeanmonod R. Adequacy and Source of History of Present Illness in Nursing Home Patients in the Emergency Department. Poster. American College of Emergency Physicians Scientific Assembly; Sept 2012; Denver, CO. Washton D, Jeanmonod R. Does Adequacy Of Nursing Home Paperwork Influence Ed Length of Stay or Admission Decisions? Society for Academic Emergency Medicine Scientific Assembly; May 2012; Chicago, IL. Wong R, Grossman M; Genzlinger M, Stehly C. Videolaryngoscopy in Trauma Patients: Theoretic and Technical Considerations. Poster. St. Luke’s University Health Network Research Conference; June 2012; Bethlehem, PA. Zweitzig DR, Riccardello NM, Pester J, Jeanmonod R, Kopnitsky M, O’Hara M. Selective Measurement of DNA Polymerase Activity Enables a Novel, Rapid, Sensitive, and Universal Detection Method for Clinically Relevant Bacteria from Platelet Concentrates. American Association of Blood Banks Annual Meeting; 2013; Denver, CO.

RESEARCH.SLUHN.ORG | 53

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION 54

Family Medicine With more than 150 family medicine physicians on staff, the St. Luke’s Family Medicine Centers provide a wide variety of health care services to meet the needs of the entire family. Under the direction of Dr. Michael A. Abgott, Chief of Family Medicine, family medicine physicians affiliated with St. Luke’s University Health Network’s six hospitals provide care throughout the Lehigh Valley and surrounding areas. Committed to medical education, the Department of Family Medicine offers a comprehensive residency program. Dr. Robert C. Langan, FAAFP, Program Director, and Dr. Martha E. Metzgar, FAAFP, Osteopathic Program Director, lead the program from the 425-bed St. Luke’s University Hospital in Bethlehem. Dr. Metzgar serves on the faculty of the Philadelphia College of Osteopathic Medicine (PCOM), Department of Family Medicine. Since 2010, the residency has published 13 papers and presented regionally and nationally 18 times. Recently, Dr. Langan was named 2015 Exemplary Teacher of the Year Award by the Pennsylvania Academy of Family Physicians. Dr. Langan, the Program Director of St. Luke’s Family Medicine Residency, is a member of the faculty of the Temple University School of

Medicine, Department of Family and Community Medicine. Also, he serves as the Medical Director of St. Luke’s Family Medicine Center, both of which are located in Bethlehem. Drs. Nguyet-Cam V. Lam, Maria Ghetu and Jennifer Ranton are Assistant Adjunct Professors of the Temple University School of Medicine, Department of Family and Community Medicine. In addition, Drs. Langan, Lam and Metzgarb completed a National Institute of Program Director Development Fellowship and Dr. Ranton completed a Behavioral Medicine Fellowship through the Society of Teachers of Family Medicine.

Family medicine physicians affiliated with St. Luke’s University Health Network’s six hospitals provide care throughout the Lehigh Valley and surrounding areas.

Students who prefer a more intimate setting may opt for the Warren Campus Family Medicine Residency Program based at the 214-bed St. Lukeâ&#x20AC;&#x2122;s Warren Hospital. Dr. Thomas McGinley is the Program Director. The residency was the first program nationally to be accredited by both the Accreditation Council for Graduate Medical Education (ACGME) and the American Osteopathic Association (AOA). The faculty of St. Lukeâ&#x20AC;&#x2122;s Family Medicine Residency takes its role as educators very seriously. In addition to the education occurring within the residency, they are active in educating family physicians throughout the United States in person and in peerreviewed journals. PUBLICATIONS AND ABSTRACTS Beck LN, Langan RC. Postinfectious Glomerulonephritis: A Case Summary. Osteopathic Family Physician. 2010; 2: 18-20. Bordelon PC, Ghetu MV, Langan RC. Recognition and Management of Vitamin D Deficiency. American Family Physician. 2009; 80(8): 841-6. Bordelon PC, Li J. Hydroxycitric Acid Dietary Supplement-Related Herbal Nephropathy. American Journal of Medicine. 2011; 124(11): 5-6. Ghetu MV, Bordelon PC, Langan RC. Mild Cognitive Impairment. Clinical Geriatrics. 2010; 8(4): 30-6. Lam NC, Gotsch PB, Langan RC. Caring for Pregnant Women and Newborns with Hepatitis B or C . American Family Physician; 2010; 82(10): 1225-9. Langan RC, Bordelon PC, Ghetu MV. Eye on the Elderly. Hypertension Care: Striking the Right Balance. Journal of Family Practice. 2009; 58(9): 460-8. Langan RC, Bordelon PC. Initial Management of the Febrile Cancer Patient with Neutropenia. Family Practice Recertification. 2007; 29(7): 30-4. Langan RC, Gotsch PB, Krafczyk MA, Skillinge DD. Ulcerative Colitis. American Family Physician. 2007; 76(9): 1323-30; 1331. Langan RC, Moher HE. Infant with a Morbilliform Rash. American Family Physician. 2010; 81(3): 327-8. Langan RC, Zawistoski KJ. Update on Vitamin B12 Deficiency. American Family Physician. 2011; 83(12): 1425-30. Langan RC. Anemia. Audio Digest Family Medicine Review. July 2014. Langan RC. Common Gastrointestinal Disorders. Audio Digest Family Medicine Review. July 2014. Langan RC. Discharge Procedures for Healthy Newborns. American Family Physician. 2006; 73: 849-52, 857-8. Langan RC. Factor V Leiden Mutation and Pregnancy. The Journal of the American Board of Family Practice / American Board of Family Practice. 2004; 17(4): 306-308.

RESEARCH.SLUHN.ORG | 55

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Langan RC. Letters to the Editor: Is Routine Testing of Vitamin B12 Cost-effective in Workup for Cognitive Impairment? American Family Physician. 2012; 85(8):online. Langan RC. Managing Endometriosis in the Primary Care Setting. Federal Practitioner. January 2006. p. 32-34. Langan RC. Nonpharmacological Management of Hypertension. Family Practice Recertification. 2006; 28(10): 39-49. Langan RC. Revision of Recommended Curriculum Guidelines for Family Medicine Residents: Allergy and Immunology. American Academy of Family Physicians. 2011 and 2008. Langan RC. Revision of Recommended Curriculum Guidelines for Family Medicine Residents: Conditions of the Eye. American Academy of Family Physicians. 2013. Langan RC. Society of Teachers of Family Medicine Residency Curriculum Resource. Electronic Fetal Monitoring; 2013. Skillinge DD, Langan RC, Krafczyk MA, McGarey ME. Benign Prostatic Hypertrophy: a Clinical Review. Osteopathic Family Physician. 2011; 3: 182-6. Valenza P, Koch-Laking A. Maternal Vitamin D Status and Pregnancy Outcomes. Evidence-Based Practice. 2013; 16(10): E-13.

PRESENTATIONS Ahmed M, Chu C, Chit T. Overcoming Structural Barriers to Adult PPSV-23 Immunization in an Academic Family Practice. Oral Presentation. 21st Annual Robert Wood Johnson Network of Affiliated Family Medicine Residencies Research Symposium; June 2013; New Brunswick, NJ. Dawkins B, Liburb J. Diabetes Mellitus Health Literacy Compliance and Complications. St. Lukeâ&#x20AC;&#x2122;s Warren Hospital Family Medicine Residency Program Alumni Day; May 2013; Phillipsburg, NJ. Feldman J. Psychological First Aid in Disaster Response. Oral Presentation. 33rd Forum for Behavioral Science in Family Medicine; Sept 2012; Chicago, IL. Ghetu M. Screening for Mild Cognitive Impairment in Primary Care. Poster. American Geriatric Society Annual Scientific Meeting; May 2011; Washington, DC. Hemeida S, Bull J, Mack A, Valenza P, Torok B, Staff T, Lee J. Case Conferences: A Means of Reduced Health Care Costs and Improved Patient Outcomes. Poster. 47th STFM Annual Spring Conference; May 2014; San Antonio, TX. Kaur J, Varghese J. Sexually Transmitted Disease Awareness Among Adolescent Patients at Coventry Family Practice. Oral. 20th Annual Robert Wood Johnson Network of Affiliated Family Medicine Residencies Research Symposium; May 2012; New Brunswick, NJ. Khodaee M, Scott LE, Valenza P, Johnson E. Prevalence of Childhood Obesity: A Pilot Study of Public Elementary School Students in Aurora, CO. Oral. 40th NAPCRG Annual Meeting; Dec 2012; New Orleans, LA. Khodaee M, Webb K, Valenza P. Do Physical Education Classes Improve Fitness Among Elementary School Students? Aurora Public Schools Experience in CO. Oral. 41st NAPCRG Annual Meeting; Nov 2013; Ottawa, Ontario.

Krblich D. Taking Charge of Our Diabetic Patientsâ&#x20AC;&#x2122; Health Experience; Optimizing Practice Performance in Diabetes Care. Poster. 22nd Annual Robert Wood Johnson Network of Affiliated Family Medicine Residencies Research Symposium; June 2014; New Brunswick, NJ. Lam N, Dao C. Impact of Teaching Medical Students in Residency Training. Poster. Pennsylvania Academy of Family Physicians Research Day; March 2014; Hershey, PA. Lam N. Abnormal Uterine Bleeding: New Nomenclature and Age-Based Approach to Treatment. Pennsylvania Academy of Family Physicians Clinical Education Series; March 2014; Hershey, PA. Lam N. Abnormal Uterine Bleeding. PCOM Family Medicine Board Review Course; Jan 2011; Philadelphia. Lam N. FMfocus: A Multi-Site Validation Study of Prenatal Ultrasound Training for Family Medicine Residents. Society of Teachers of Family Medicine Spring Conference; May 2014. Lam N. Prenatal Care. PCOM Family Medicine Board Review Course, Jan 2010; Philadelphia, PA. Lam N. Update on Cervical Cancer Screening and Treatment. Pennsylvania Academy of Family Physicians Clinical Education Series; May 2009; Hershey, PA. Langan R. Benign Prostatic Hypertrophy. Pennsylvania Academy of Family Physicians Clinical Education Series; Nov 2013; Erie, PA. Langan R. Diverticulitis. Pennsylvania Academy of Family Physicians Clinical Education Series; July 2012; Annapolis, MD.

RESEARCH.SLUHN.ORG | 57

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Langan R. Dyslipidemia. Pennsylvania Academy of Family Physicians Clinical Education Series; Nov 2010; Valley Forge, PA. Langan R. Hypertension and Pregnancy. Susquehanna Health Systems Grand Rounds, Sept 2012; Williamsport, PA. Langan R. Hypertension, Susquehanna Health Systems Grand Rounds. Sept 2010; Williamsport, PA. Langan R. JNC 8: An Update, Susquehanna Health Systems Grand Rounds; Nov 2014; Williamsport, PA. Langan R. Prostate Potpourri. American Academy of Family Physicians Scientific Assembly, Oct 2014; Washington, DC. Langan R. PSA and the Treatment of Localized Prostate Cancer. American Academy of Family Physicians Scientific Assembly; Oct 14; Washington, DC. Langan R. The First Five Years: Reminisces of a Junior PD Program Directors’ Workshop. Association of Family Medicine Residency Directors; June 2012; Kansas City, MO, June 2012. Langan R. What I Think About Hematology. Pennsylvania Academy of Family Physicians Clinical Education Series, March 2012; Valley Forge, PA. McGinley TC. Joint Injection Workshop. Oral Presentation. Northeast Region Meeting of Family Medicine Education Consortium; Nov 2013; Philadelphia, PA. Metzgar M. Women’s Health. PCOM Family Medicine Board Review Course; Jan 2013, 2014; Philadelphia, PA. Newman J, Fahmy H. Assessing Patient Hemoglobin A1C: Follow-Up and Improvement After Patient Education at Coventry Family Practice. Poster Presentation. 22nd Annual Robert Wood Johnson Network of Affiliated Family Medicine Residencies Research Symposium; June 2014; New Brunswick, NJ. Parmar L, Eicher C, Spataro J, Siciliano M. Sexually Transmitted Infection Education for Adolescents and Young Adults. Poster Presentation. 22nd Annual Robert Wood Johnson Network of Affiliated Family Medicine Residencies Research Symposium; June 2014; New Brunswick, NJ.

Patel S, Nguyen T. Interventions to Improve the HPV Immunization Rate of Patients at St. Luke’s Coventry Family Practice. St. Luke’s Warren Hospital Family Medicine Residency Program Alumni Day; May 2013; Phillipsburg, NJ. Ranton J. Diabetes Mellitus. PCOM Family Medicine Board Review Course; Jan 2014; Philadelphia, PA. Sonaike V, McGinley TC, Buch R, Stoltzfus J. Identifying the Usefulness of Inpatient Nuclear Stress Testing of Low Risk Patients Using the HEART Score. Oral. 22nd Annual Robert Wood Johnson Network of Affiliated Family Medicine Residencies Research Symposium; June 2014; New Brunswick, NJ. Valenza P, Gold S, Lee J. Utilizing Motivational Interviewing as a Predictor of Pediatric Obesity Group Visit Attendance in a Federally Qualified Community Health Center. Poster. 41st NAPCRG Annual Meeting; Nov 2013; Ottawa, Ontario. Valenza P, Kulkarni M, Deffenbacher D. Anti-NMethyl-D-Aspartate Receptor Encephalitis in an Immunosuppressed Patient. Poster Presentation. 11th Annual Rocky Mountain Hospital Medicine Symposium; Aug 2013; Denver, CO. Valenza P, Webb K, Khodaee M. Correlation of BMI with Fitness Level among Public School Students in Aurora, CO. Poster Presentation. 41st NAPCRG Annual Meeting; Nov 2013; Ottawa, Ontario. Valenza P, Webb K, Khodaee M. Correlation of BMI with Fitness Level among Public School Students in Aurora, CO. Poster Presentation. State Network of CO Ambulatory Practices & Partners Convocation; Sept 2013; Denver, CO. FACULTY APPOINTMENTS Raymond Buch, MD, DABFP • Member, Operations Committee, Rutgers RWJMS Department of Family Medicine and Community Health Network of Affiliated Family Medicine Residencies • Member, Credentials Committee, St. Luke’s Warren Hospital • School Physician, Phillipsburg School District

Ching-Huey Chu, MD • Member, Credentials Committee, St. Luke’s Warren Hospital Eugene Decker, DO • Medical Director, DeSales University Physician Assistant Program • Member, DSRIP Committee, St. Luke’s Warren Hospital • Chairman, Child Sexual Abuse Expert, Allentown Diocesan Review Board • School Physician, Lopatcong Elementary School/Harmony Elementary School • ACLS, PALS, NRP Instructor James Feldman, LCSW, PhD • Member, Research Committee, Rutgers RWJMS Department of Family Medicine and Community Health Network of Affiliated Family Medicine Residencies • Member, DSRIP Committee, St. Luke’s Warren Hospital • Local Editor, Family Physicians Inquiry Network (FPIN) Helaine Levine, MD, FAAP • School Physician, Phillipsburg School District • Clinical Assistant Professor, Philadelphia College of Osteopathic Medicine (PCOM) Thomas McGinley, MD, FAAFP • Member, Program Directors Committee, Rutgers RWJMS Department of Family Medicine and Community Health Network of Affiliated Family Medicine Residencies • Member, Graduate Medical Education Committee, St. Luke’s University Hospital Network Mary Siciliano, DO • DO Director of Medical Education, Philadelphia College of Osteopathic Medicine (PCOM) • Member, Bylaws Committee, St. Luke’s Warren Hospital • Member, Women’s Health Committee, St. Luke’s Warren Hospital • TEAMSTTEPS Educator, St. Luke’s Warren Hospital Pamela Valenza, MD • Clinical Assistant Professor, Temple University School of Medicine • Board Director, Pennsylvania Academy of Family Physicians • Member, Task Force on Board Restructure/Future of the Board, Pennsylvania Academy of Family Physicians • Member, Research Committee, Rutgers RWJMS Department of Family Medicine and Community Health Network of Affiliated Family Medicine Residencies • Member, DSRIP Committee, St. Luke’s Warren Hospital • Member, Research Faculty Council, St. Luke’s University Hospital Network • Local Editor, Family Physicians Inquiry Network (FPIN) • ALSO Instructor

RESEARCH.SLUHN.ORG | 59

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Geriatric Medicine St. Luke’s University Health Network provides a positive aging experience for older adults in the community through specialized services and care designed especially for seniors. Recognizing that with age come unique needs and challenges, St. Luke’s is committed to helping seniors and caregivers get the most out of life by offering a wealth of programs, classes and tools designed by geriatric specialists. Physicians, nurses, therapists and other staff, many of whom have specialized training in geriatrics, have developed programs to better meet the needs of older patients. For example, the Emergency Department at St. Luke’s University Hospital – Bethlehem opened a special Older Adult Section. It offers a gentler, quieter alternative to the hustle and bustle of the traditional emergency room. The network’s innovative services also include the Older Adult Behavioral Health Unit. A geriatric-trained psychiatrist, a gerontologist, medical-surgical nurses, mental health technicians, case managers and activity therapists staff the unit. In addition to treating patients’ behavioral health conditions, the team also addresses the medical health concerns that often accompany advanced age, such as diabetes, hypertension and heart disease. The network also provides comprehensive evaluations and recommendations for senior care through St. Luke’s Senior Care Associates. A team of geriatricians, nurse practitioners and social workers staff the program. The team provides specialized services and care designed for seniors at St. Luke’s Center for Positive Aging. Through the Center, the team works with patients, family members and family physicians to assess the patient’s physical, emotional, social and functional needs and assists in planning for their future. St. Luke’s Senior Care Associates also provide inpatient comprehensive geriatric assessment through the Acute Care of Elderly (ACE) Program. ACE team includes geriatricians, geriatric pharmacy, nursing, case management, and physical and occupational therapy. The goal of the ACE program is to reduce and prevent hospital complications for seniors, which includes falls, delirium, cognitive decline, functional decline, immobility and polypharmacy.

The Preoperative Geriatric Assessment Initiative, led by a nurse navigator, has been implemented at St. Luke’s University Hospital – Bethlehem. The nurse navigator provides geriatric assessment and recommendations for older adults undergoing elective surgery. She works closely with anesthesiologists, surgeons and primary care physicians to prevent postoperative hospital complications. The network is restructuring the post-acute care services through the Bundled Payment Initiative. St. Luke’s team and Senior Care Services work closely with the nursing home facilities in our service area to improve quality of care, outcomes and transition of care. St. Luke’s University Health Network hospitals have achieved designation as NICHE hospitals. NICHE (Nurses Improving Care for Healthsystem Elders) is the leading nurse-driven program designed to help hospitals and health care organizations improve the care of older adults. Through NICHE, St. Luke’s will be recognized as a health network that is highly skilled in providing integrated clinical and supportive care directed at the unique and sensitive needs of older patients and their caregivers. GERIATRIC FELLOWSHIP The St. Luke’s Geriatric Fellowship program trains physicians to become outstanding geriatricians. The graduate physicians are prepared to provide exceptional patient care to older adults and lead the senior care services in their communities.

St. Luke’s is committed to helping seniors and caregivers get the most out of life.

PUBLICATIONS Burfeind WR, Tong BC, O’Branski E, Herndon JE, Toloza EM, D’Amico TA, Harpole LH, Harpole DH. Quality of Life Outcomes are Equivalent after Lobectomy in the Elderly. The Journal of Thoracic and Cardiovascular Surgery. 2008; 136(3): 597-604. doi: 10.1016/j. jtcvs.2008.02.093. Hamden K, Agresti D, Jeanmonod R, Woods D, Reiter M, Jeanmonod D. Characteristics of Elderly Fall Patients with Baseline Mental Status: High-risk Features for Intracranial Injury. The American Journal of Emergency Medicine. May 2014; 32(8): 890–894. doi: 10.1016/j.ajem.2014.04.051. Nelson D, Washton D, Jeanmonod R. Communication Gaps in Nursing Home Transfers to the ED: Impact on Turnaround Time, Disposition, and Diagnostic Testing. The American Journal of Emergency Medicine. 2013; 31(4): 712-716. doi: 10.1016/j.ajem.2012.11.024. Tripathi RS, Russell SB, Lyaker MR, Stawicki SP, Papadimos TJ. An Iatrogenic Metabolic Encephalopathy in a Nonagenarian: The Dilemma of a Critical Miss as a Possible Social Dismissal. International Journal of Critical Illness and Injury Science. 2013; 3(4): 282-283. doi: 10.4103/2229-5151.124169. PRESENTATIONS Agresti D, Jeanmonod R. Anti-platelet and Anti-coagulants Do Not Increase Traumatic Intracranial Bleeds in Elderly Fall Victims. The Society for Academic Emergency Medicine 2013 Annual Meeting; May 2013; Atlanta, GA. Evans D, Jeanmonod D, Pester J, Jeanmonod R. Nexus in the Elderly Fall Patient: What is Distracting? Poster. The Society for Academic Emergency Medicine 2014 Annual Meeting; May 2014; Dallas, TX. Ulitsky A, Jeanmonod R. Falls in the Elderly: A Look at Fall Recidivism and Hemostasis Inhibiting Agents. St. Luke’s University Network Research Forum; June 2013; Bethlehem, PA. Washton D, Jeanmonod R. Adequacy and Source of History of Present Illness in Nursing Home Patients in the Emergency Department. American College of Emergency Physicians Scientific Assembly; 2012; Denver, CO.

RESEARCH.SLUHN.ORG | 61

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Heart & Vascular Recognized for its excellence in cardiovascular medicine, the St. Luke’s Heart & Vascular Center is committed to the three pillars of modern medicine — service, medical education and research. In 2014, Truven Health Analytics (formerly known as Thomson Reuters), a leading provider of information and solutions to improve the cost and quality of health care, named St. Luke’s University Health Network one of the nation’s 50 Top Cardiovascular Hospitals — the sixth time that St. Luke’s was named to Truven’s Top Cardiovascular Hospitals list. Led by Dr. Raymond Durkin, Network Chairman of the Department of Cardiovascular Medicine, and Dr. Stephen Olenchock, Section Chief of Cardiovascular Surgery, the St. Luke’s Heart & Vascular Center has earned many achievements, honors and awards. The Center: • Was named a Truven Top 50 Cardiovascular Hospital in 2012 and 2014. • Achieved the highest rating for quality of cardiac surgery from the Society of Thoracic Surgeons. • Has the lowest mortality index in the region for heart disease and heart surgery patients. • Was selected as one of the first institutions in the country to offer both transcatheter aortic valve replacement (TAVR) and MitraClip percutaneous mitral valve repair due to its exceptional outcomes and multidisciplinary team approach. • Was first in the United States to install GE Healthcare’s Discovery IGS 730 Hybrid Operating Room and is one of a handful of international GE Healthcare show sites. • Operates the first accredited Chest Pain Center in the Lehigh Valley region at the St. Luke’s University Hospital – Bethlehem. St. Luke’s Heart & Vascular Center offers the most advanced technologies, diagnostics and treatments to provide superior care. Some leading-edge treatments include: • Minimally invasive mitral and aortic valve surgery • Mitral valve repair including complex disease processes such as Barlow’s valve

• Complex aortic surgery for aneurysmal disease utilizing open and endovascular approach including TEAVR. This includes an aortic clinic that longitudinally follows and treats patients with aortic aneurysmal disease. • Structural heart program and valve clinic with expertise transcatheter aortic valve replacement, MitraClip percutaneous mitral repair and ASD closure. • A comprehensive heart failure clinic including evaluation for transplant, treatment of pulmonary hypertension, hypertrophic cardiomyopathy and advanced medical support utilizing extracorporeal life support (ECLS), also known as extracorporeal membrane oxygenation (ECMO) and the Heart Mate II Left Ventricular Assist Device (LVAD) as a destination therapy program. • Full service interventional cardiology program including 24/7 MI coverage, structural heart program and PAD evaluation and treatment. • Advanced lead management for pacemakers and defibrillators - where malfunctioning leads and device infections are taken care of by a combined team (thoracic surgeon, electrophysiologists and cardiac surgeon) in the GE Healthcare’s 730 Hybrid Operating Room, providing the best outcomes for patients. • Subcutaneous defibrillators (SICD) — a new defibrillator for select group of patients with high risk of sudden death. • Advanced ventricular tachycardia management — taking care of high risk abnormal electrical circuits in the heart using a combined approach from both inside and outside the heart. • Atrial fibrillation center — using multimodal therapy for atrial fibrillation, the most common heart rhythm disorder in the United States. In addition to usual medications and radiofrequency ablation (using heat to burn abnormal electrical circuits) St. Luke’s also offers cryo-ablation (freezing abnormal tissues) and hybrid ablation (unique technique of ablation with cardiac surgeon and electrophysiologist working together in hybrid operating room).

St. Luke’s University Health Network one of the nation’s 50 Top Cardiovascular Hospitals.

St. Luke’s University Health Network believes that every patient with heart or vascular disease should have access to high quality cardiovascular services close to home. As a result, Heart and Vascular Centers are located throughout the Lehigh Valley and the surrounding areas. Providing services in Bucks, Carbon, Lehigh, Monroe, Montgomery, Northampton and Schuylkill counties in Pennsylvania and Warren County in New Jersey, St. Luke’s Heart & Vascular Center has: • 13 cardiology offices • Cardiac catheterization capability at three hospitals • Three accredited chest pain centers • 31 cardiologists • Three cardiac surgeons • Four vascular surgeons • Six interventional radiologists • Three electrophysiologists • Five interventional cardiologists St. Luke’s University Health Network is fully committed to the second pillar of modern medicine — medical education. St. Luke’s provides training opportunity to medical students and residents from across the country to train in an ACGME (American College of Graduate Medical Education) recognized Cardiovascular Fellowship program and Interventional Cardiology Fellowship. Cardiology fellows from the program have successfully gone on to higher training and desirable positions across the country. St. Luke’s University Health Network is firmly entrenched in medical research, the third pillar of modern medicine. Led by Dr. Jamshid Shirani, program director of the Cardiovascular Fellowship Program, physicians and fellows of the Department of Cardiovascular Medicine have published more than 200 peer-reviewed papers in internationally recognized journals. A Research Department led by Dr. Stanislaw Stawicki is fully committed to improving medical education and patient care through clinical research.

RESEARCH.SLUHN.ORG | 63

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Crabtree TD, Kosinski AS, Puri V, Burfeind WR, et al. Evaluation of the Reliability of Clinical Staging of T2N0 Esophageal Cancer: A Review of the Society of Thoracic Surgeons Database. Annals of Thoracic Surgery. 2013; 96: 382-90. doi: 10.1016/j. athoracsur.2013.03.093. doi: 10.1016/j. jemermed.2010.05.036.

Alaeddini J, Gaeta TJ, Levine MD, Shirani J. First-Degree Atrioventricular Block. Medscape reference. Updated: February 2014. Available at: http://emedicine. medscape.com/article/161829-overview.

Ebrille E, Chandra VM, Syed F, Del Carpio Munoz F, Nanda S, Hai JJ, Cha YM, Friedman PA, Hammill SC, Munger TM, Venkatachalam KL, Packer DL, Asirvatham SJ. Distinguishing Ventricular Arrhythmia Originating from the Right Coronary Cusp, Peripulmonic Valve Area, and the Right Ventricular Outflow Tract: Utility of Lead I. Journal of Cardiovascular Electrophysiology. April 2014; 25(4): 404-410. doi:10.1111/jce.12330.

Alaeddini J, Shirani J. Angina Pectoris. Medscape reference. Updated: March 27, 2014. Available at: http:// emedicine.medscape.com/article/150215-overview.

Ebrille E, Nanda S, Noheria A, Asirvatham S. Conference Paper: Electrophysiologic Features and Ablation of Junctional Tachycardia. Circulation. Nov 2014.

Burfeind WR. Bullectomy for Symptomatic or Complicated Giant Lung Bullae. Invited Commentary. Annals of Thoracic Surgery. Feb 2014; 97(2): 431.

Genzlinger MA, Eberhardt M. Analyzing Prominent T Waves and ST-segment Abnormalities in Acute Myocardial Infarction. Journal of Emergency Medicine. Aug 2012; 43(2): e81-e85. doi: http://dx.doi.org/10.1016/ j.jemermed.2009.08.032

PUBLICATIONS

Burfeind WR. Chylothorax Complicating Pulmonary Resection for Lung Cancer: Effective Management and Pleurodesis. Invited Commentary. Annals of Thoracic Surgery. Feb 2014; 97(2): 413. Burfeind WR. Influence of Cigarette Smoking on Survival and Tumor Invasiveness in Clinical Stage IA Lung Adenocarcinoma. Invited Commentary. Annals of Thoracic Surgery. May 2012; 93(5): 1632.

Jamshid Shirani, Vasken Dilsizian. Novel Molecular Angiotensin Converting Enzyme and Angiotensin Receptor Imaging Techniques. Current Cardiology Report. Apr 2014; 16(4): 466. doi:10.1007/s11886-014-0466-7.

Cotarlan V, Ho D, Pineda J, Qureshi A, Shirani J. Impact of Clinical Predictors and Routine Coronary Artery Disease Testing on Outcome of Patients Admitted to Chest Pain Decision Unit. Clinical Cardiology. March 2014; 37: 146-151. doi: 10.1002/clc.22229.

Liang J, Hebl V, DeSimone C, Madhavan M, Nanda S, Kapa S, Maleszewski J, Edwards W, Reeder G, Cooper L, Asirvatham S. Electrogram Guidance: A Method to Increase the Precision and Diagnostic Yield of Endomyocardial Biopsy for Suspected Cardiac Sarcoidosis and Myocarditis. Journal of the American College of Cardiology. Oct 2014; 2(5): 466-73. doi: 10.1016/j.jchf.2014.03.015.

Nizam A, Mylavarapu K, Thomas D, Briskin K, Wu B, Saluja D, Wong S. Lacosamide-induced Second-degree Atrioventricular Block in a Patient with Partial Epilepsy. Epilepsia. July 2011; 52(10): e153-5. doi:10.1111/j.1528-1167.2011.03212.x.

Coven DL, Kalyanasundaram A, Shirani J. Acute Coronary Syndrome. Medscape Reference. Updated December 22, 2014. Available at: http://emedicine. medscape.com/article/1910735-overview.

Roberts WC, Filardo G, Ko JM, Siegel RJ, Dollar AL, Ross EM, Shirani J. Comparison of Total 12-Lead QRS Voltage in a Variety of Cardiac Conditions and Its Usefulness in Predicting Increased Cardiac Mass. The American Journal of Cardiology. June 2013; 112(6). doi:10.1016/j.amjcard.2013.04.061.

Roberts WC. Vowels TJ, Filardo G, Ko JM, Mathur RP, Shirani J. Natural History of Unoperated Aortic Stenosis During a 50-Year Period of Cardiac Valve Replacement. The American Journal of Cardiology. Aug 2013; 112(4): 541-43. doi:10.1016/j.amjcard.2013.04.020. Seder DB, Patel N, McPherson J, McMullan P, Kern KB, Unger B, Nanda S, Hacobian M, Kelley MB, Nielsen N, Dziodzio J, Mooney M. Geriatric Experience Following Cardiac Arrest at Six Interventional Cardiology Centers in the United States. 2006-2011: Interplay of Age, Do-Not-Resuscitate Order and Outcomes. Critical Care Medicine. Oct 2013; 42(2). doi:10.1097/CCM.0b013e3182a26ec6. Shirani J, Acharya Y, Kalyanasundaram A, Pourmoghadam KK. Cor Triatriatum. Medscape reference. Updated December 18, 2014. Available at: http://emedicine.medscape.com/ article/154168-overview. Shirani J, Brofferio A. Isolated Coronary Artery Anomalies. Medscape Reference. Updated: December 18, 2014. Available at: http://emedicine.medscape.com/article/153512-overview. Shirani J, Dilsizian V. Novel Molecular ACE and Angiotensin Receptor Imaging Techniques. Current Cardiology Reports. April 2014; 16: 466. doi: 10.1007/s11886-014-0466-7. Shirani J, Pranesh S, Menhaji K, Cotarlan V, Brofferio A. Dobutamine-Induced Myocardial Ischemia and ST-Segment Elevation in Collateral-Dependent Myocardium. The American Journal of Cardiology. Nov 2013; 112(9): 1293-7. doi:10.1016/j.amjcard.2013.05.072. Singh VN, Aggarwal K, Sharma RK, Shirani J, Strom JA, Suksanong M. Myocardial abscess. Medscape reference. Updated: November 14, 2014. Available at: http://emedicine. medscape.com/article/223700-overview.

RESEARCH.SLUHN.ORG | 65

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

St. Julien JB, Aldrich MC, Sheng S, Deppen SA, Burfeind WR, Putnam JB, Lambright ES, Nesbitt JC, Grogan EL. Obesity Increases Operating Room Time for Lobectomy in the Society of Thoracic Surgeons Database. Annals of Thoracic Surgery. Dec 2012; 94(6): 1841-7 doi: 10.1016/j.athoracsur.2012.08.006. Surya P Bhatt, T K Luqman-Arafath, Arun K Gupta, Anant Mohan, Jill C Stoltzfus, Tanujit Dey, Sudip Nanda, Randeep Guleria. Volitional Pursed Lips Breathing in Patients with Stable Chronic Obstructive Pulmonary Disease Improves Exercise Capacity. Chronic Respiratory Disease. Nov 2012; 10(1). doi:10.1177/1479972312464244. Tong BC, Kosinski AS, Burfeind WR, Onaitis MW, Berry MF, Harpole DH, D’Amico TA. Sex Differences in Early Outcomes after Lung Cancer Resection: Analysis of the Society of Thoracic Surgeons General Thoracic Database. The Journal of Thoracic and Cardiovascular Surgery. July 2014; 148(1): 13-18. doi: 10.1016/j. jtcvs.2014.03.012. Wheeler G, Kropf J, Jeanmonod R. Vasculitis Presenting with Myocardial Infarction, Stroke and Aortitis in a Middle-aged Man. Journal of Emergency Medicine. Oct 2012; 43(4): 655-8.

PRESENTATIONS Crabtree TD, Kosinski AS, Puri V, Burfeind WR, et al. Evaluation of the Reliability of Clinical Staging of T2N0 Esophageal Cancer: A Review of the Society of Thoracic Surgeons Database. Oral. Richard E. Clark Award winning paper. The Society of Thoracic Surgeons; Jan 2013; Ft. Lauderdale, FL. Shirani J. Ethical Issues in Nuclear Cardiology: A Case-Based Discussion. Panel Discussion. 19th Annual Scientific Session of the American Society of Nuclear Cardiology; Sept 2014; Boston, MA. Shirani J. Imaging Angiotensin Receptor and Angiotensin Converting Enzyme in the Heart. 19th World Congress on Heart Disease. International Academy of Cardiology. Annual Scientific Sessions; July 2014; Boston, MA. Shirani J. Is Ischemia the Most Powerful Indicator of Myocardial Viability? Current Cardiology Reports. May 2013; 15(5): 354. doi:10.1007/s11886-013-0354-6. Shirani J. Significance of Myocardial Viability Assessment in Management of Chronic Total Coronary Occlusion. 21st Turkish Annual Interventional Cardiology Meeting with Live Cases; March 2014; Antalya, Turkey. Shirani J. Update on Evaluation and Care of Patients with Hypertrophic Cardiomyopathy. 16th annual Cardiovascular Nursing Symposium - Walter W. Buckley Jr. Symposium in Cardiac Medicine; Oct 2014; Macungie, PA. Shirani J. Update on the Auscultatory Signs of Heart Disease. 9th Annual Cardiac Update for the Practitioner, St. Luke’s Hospital Heart and Vascular Center; Feb 2014; Center Valley, PA.

SCIENTIFIC ABSTRACTS Abichandani A, Vefali H, Signarovitz D. Chebrolu H, Shirani J, Traub D. Clinical Impact of Implantable Loop Recorders on Management of Patients with Recurrent Syncope or Cryptogenic Cerebrovascular Accident. Circulation. 2014; 130: A18639. Chebrolu L, Abichandani A, Prutzman D, Masceranhas E, Shirani J, Traub D. Magnetic Resonance Imaging Conditional Pacemaker: Trend Setting Technology – A Single Center Experience. Journal of Heart Disease. 2014; 11: 81. Manda Y, Chebrolu LH, Shirani J. Influence of Prehypertension and Stage-1 Hypertension on the Outcome of Adults with Hypertrophic Cardiomyopathy. Journal of Heart Disease. 2014; 11: 114. Mohammadi M, Shirani J. Value of Thoracic Aortic Calcium in Prediction of Obstructive Coronary Artery Disease. Journal of Heart Disease. 2014; 11: 53. Nanda S, Levin V, Martinez MW. Ventricular Tachycardia in “End Stage” Hypertrophic Cardiomyopathy: A Role of Dronedarone. Minerva Cardioangiologica. Dec 2012; 60(6): 637-42. Shirani J. Imaging Angiotensin Receptor and Angiotensin Converting Enzyme in the Heart. Journal of Heart Disease. 2014; 11: 3. Vefali H, Shirani J. Epicardial Adipose Tissue Thickness Underestimate Total Cardiac Fat Content: Comparison of Unidimensional and Volumetric Methods. Journal of Heart Disease. 2014; 11: 94. APPOINTMENTS – CARDIOLOGY: (TEACHING, OFFICES HELD, BOARD POSITIONS) Dr. Jamshid Shirani • Clinical Professor of Medicine (Cardiology), Department of Medicine, Temple University School of Medicine, Philadelphia, PA. • Clinical Professor of Medicine (Cardiology), Department of Internal Medicine, Philadelphia College of Osteopathy, Philadelphia, PA. HONORS/AWARDS – CARDIOLOGY Dr. Jamshid Shirani • Physician Honoree Award, June 2014, Office of Academic Affairs, St. Luke’s University Health Network. • Teacher of the Year Award, June 2014, Department of Cardiology, St. Luke’s University Health Network. • Best Doctors in America 2014 Consumers’ Research Council of America. Guide to America’s Top Cardiologists 2014. GRANTS – CARDIOLOGY A Phase 2/3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effect of GS-6615 on Exercise Capacity in Subjects with Symptomatic Hypertrophic Cardiomyopathy, Gilead Sciences, Inc., Foster City, California, December 2014.

RESEARCH.SLUHN.ORG | 67

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Internal Medicine & Subspecialties The St. Luke’s Department of Internal Medicine has made a robust contribution to research and medical publications. Throughout the Lehigh Valley and surrounding areas, St. Luke’s more than 80 internal medicine physicians apply scientific knowledge and clinical expertise to the diagnosis, treatment and compassionate care of adults across the spectrum from health to complex illness. Many of our internal medicine physicians are also involved in cultivating future internists through the St. Luke’s Internal Medicine Residency Program. St. Luke’s offers two options. The first Internal Medicine Residency Program option falls under the Department of Medicine and is led by Gloria Fioravanti, DO, FACP, Program Director, Internal Medicine Residency, St. Luke’s University Health Network. Dr. Fioravanti is also a faculty member of Temple University School of Medicine. Fully accredited by the Accreditation Council for Graduate Medical Education (ACGME), the program excels amid state-of-the-art facilities, strong administrative support and a dedicated faculty. It enjoys a high passage rate on the American Board of Internal Medicine certifying examination. Also, the Internal Medicine Residency Program supports an ACGMEaccredited Cardiology Fellowship. Cara Ruggerio, DO, leads the Osteopathic Internal Medicine Residency Program at St. Luke’s. She is also a faculty member of the Temple University School of Medicine. The program is fully accredited by the Council on Post-Doctoral Training of the American Osteopathic Association, as well as the Accreditation Council for Graduate Medical Education (ACGME). Upon successful completion of the program, residents take both the American College of Osteopathic Internal Medicine Board examination and the American Board of Internal Medicine (ABIM) certifying examination. This enables residents interested in fellowships to pursue both osteopathic and/or allopathic fellowshiptraining opportunities. The program enjoys a high passage rate on both the American College of Osteopathic Internist and the American Board of Internal Medicine certifying examination.

In addition to internal medicine physicians who provide primary care, many St. Luke’s physicians certified in internal medicine have received advanced training and certification in fields including cardiology, critical care, endocrinology, gastroenterology, infectious diseases, nephrology, neurology, oncology and pulmonology. CARDIOLOGY See Heart & Vascular section on page 62. CRITICAL CARE See Critical Care section on page 32. ENDOCRINOLOGY St. Luke’s Center for Diabetes & Endocrinology physicians are certified specialists who treat adults with diabetes and disorders of the hypothalamus, pituitary gland, pineal gland, parathyroid glands, adrenal gland, ovaries and testes. Dr. Mohammad Arastu serves as the Section Chief of Endocrinology for St. Luke’s University Health Network. Located in Center Valley, the Center provides care to patients in other St. Luke’s University Health Network locations through telehealth technology. Among the endocrinologists involved in telemedicine is Dr. Bankim Bhatt. Also a Clinical Assistant Professor of Medicine at Temple University’s School of Medicine, Dr. Bhatt is particularly interested in treating patients with diabetes and has presented his research findings at national meetings and has published them in leading medical journals.

More than 80 internal medicine physicians apply scientific knowledge and clinical expertise.

GASTROENTEROLOGY More than 30 gastroenterologists affiliated with St. Luke’s University Health Network’s six hospitals are committed to caring for patients with digestive health disorders. Their expertise, combined with their focus on each patient, provides patients with high quality gastroenterological care. Many St. Luke’s gastroenterologists specialize in areas such as advanced endoscopy or oncological gastroenterology. Dr. Steven F. Solga serves as the Section Chief of Gastroenterology for St. Luke’s University Health Network. He is a nationally known expert in breath ammonia research.

INFECTIOUS DISEASES Led by Dr. Jeffrey Jahre, St. Luke’s Senior Vice President for Medical and Academic Affairs and Chief, Infectious Diseases, seven physicians affiliated with St. Luke’s University Health Network are available to prevent, diagnose and treat infectious diseases caused by organisms such as bacteria, viruses, fungi and parasites. Experts in epidemiology, these physicians are active in public health activities, such as identifying sources of infectious diseases, preventing their spread and educating the public. NEPHROLOGY St. Luke’s University Health Network is affiliated with 13 nephrologists. They provide kidney care and treat diseases of the kidneys. Office locations include Bethlehem, Easton, Jim Thorpe and Palmerton. Dr. Robert Pursell serves as Section Chief of Nephrology for St. Luke’s University Health Network. NEUROLOGY See Neurosciences section on page 76.

RESEARCH.SLUHN.ORG | 69

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

ONCOLOGY See Oncology section on page 84. PULMONOLOGY St. Luke’s Pulmonary & Critical Care Associates, as well as private practice pulmonologists affiliated with St. Luke’s University Health Network, treat lung diseases and recurring pulmonary conditions. Under the leadership of Dr. Livia Bratis, Section Chief of Pulmonary Medicine at St. Luke’s University Health Network, approximately 15 physicians provide patients with up-to-date treatments. These dedicated professionals continually search for new therapeutic methods and technologies to improve patient care and quality of life. Specialty areas within pulmonology include critical care and sleep medicine. RHEUMATOLOGY Under the direction of Dr. Charles Ludivico, seven rheumatologists diagnose and treat rheumatologic conditions such as rheumatoid arthritis, lupus, osteoarthritis, fibromyalgia and gout. Recently, St. Luke’s University Health Network recruited Dr. Sherilyn McCollum. PUBLICATIONS Brummond A, Sefcik S, Halvorsen A, Chaudhry S, Arora V, Adams M, Lucarelli M, McDonald F, Reed D. Characteristics and Costs of Resident Recruitment: A National Survey of Internal Medicine Residency Program Directors. MPH American Journal of Medicine. July 2013. Kazi R, Kazi H, Ruggeri C, Ender P. Eosinophilic Meningitis Secondary to Intravenous Vancomycin. The Journal of Pharmacy Practice. June 2013; 26(3): 261-3. Kazi R, Kazi H, Ruggeri C, Ender PT. Eosinophilic Meningitis Secondary to Intravenous Vancomycin. Journal of Pharmacy Practice. June 2013; 26(3): 261-3 doi: 10.1177/0897190012452310. Perez Acosta ME, Ender PT, Smith EM, Jahre JA. Babesia Microti Infection, Eastern Pennsylvania, USA. Emerging Infectious Diseases. July 2013; 19: 1105-7. PMID:23764008.

Polimera H, Kanagali S, Pursell R, Leh D. Gone but Not Forgotten. Published in the ASN’s 2013 Abstract Supplement of Journal of the American Society of Nephrology; Oct 2013. Samuel B, Fioravanti G, Polimera H, Meyers A, Dorville F, Little E. Autoimmune Hepatitis in a 20-Year-Old African American Man. Lab Medicine. Spring 2014; 45:000. Pub Med 24868999. Samuel B, Fioravanti G, Smith A, Longo S, Axelband J. Nocardia as a Complication in a 30-year-old Immunocomprised Hispanic Woman. Lab Medicine. Pub Med 25527610.

PRESENTATIONS Acosta M, Gallagher T, Dylewski J, Leh D. Resurrection Surprise. American College of Physicians PA Eastern Region Abstract and Poster Competition 2013; Nov 2013; Scranton, PA. Dhamdhere M, Cutitta C, Leh D. Traveling Left Ventricular Thrombus. American College of Physicians PA Eastern Region Abstract and Poster Competition 2013; Nov 2013; Scranton, PA. Dhamdhere M, Radoianu N, Matin A, Leh D. Steroids for the Masses. American College of Physicians PA Eastern Region Abstract and Poster Competition 2013; Nov 2013; Scranton, PA. Dhamdhere M, Shaik S, Paprota J, Fioravanti G. Atypical Case of Severe Idiopathic Pulmonary Arterial Hypertension. New York Thoracic Society Meeting; Spring 2013. Dhamdhere M, Shaik S, Paprota J, Fioravanti G. Atypical Case of Severe Idiopathic Pulmonary Arterial Hypertension. American College of Physicians PA Eastern Region Abstract and Poster Competition 2013; Nov 2013; Scranton, PA. Dhamdhere M. Critical Mass. Poster. Society of General Internal Medicine 37th Annual Meeting; April 2014. Dylewski J, Marshall C, Ruggeri C, Leh D. More than ‘Simple’ Back Pain. Poster. American College of Osteopathic Internists; Oct 2012; Orlando, FL. Dylewski J, Trivedi H, Pursell R and Snyder R. The Use of a Kidney Based Probiotic for Chronic Kidney Disease: Recognition of the Importance of the Gut. Poster. National Meeting of the National Kidney Foundation; April 2013.

Dylewski J. More than ‘Simple’ Back Pain. Poster. American College of Physicians (Eastern PA) Associates’ and Medical Students’ Annual Meeting; The Commonwealth Medical College; Oct 2012; Scranton, PA. Dylewski J. Severe Malaria Causing Profound Hemoglobinuria and Acute Kidney Injury. Poster. Society of General Internal Medicine, 37th Annual Meeting; April 2014;. Kazi H, Boylan J. Intestinal Angioedema: It’s Time to Use a Different Antihypertensive. Poster. American College of Physicians Eastern Regional Associates Conference; Oct 2011. Kazi H, Shaik S, Leh D. Time for Change: Dyslipidemia Management by Internal Medicine Housestaff. Poster. American Association of Clinical Endocrinologists 21st Annual Scientific and Clinical Congress; May 2012; Philadelphia, PA. Kazi H, Shaik S. Relentless Diarrhea: Broadening the Differential. Poster. National Meeting of the American College of Physicians Resident Abstract Competition; April 2012. Kazi R, Kazi H, Shaik S, Gajanana D, Bhatt B. Weight Gain: A Treatment for Dysautonomia? National Meeting of the American College of Physicians Resident Abstract Competition. Poster. April 2013. Marcela Acosta-Perez MD, Axelband J. Implementation of Sepsis Screening and Management Bundles Reduces Mortality. Poster Finalist. American College of Physicians National Meeting; April 2014.

RESEARCH.SLUHN.ORG | 71

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Marshall C, Pursell R, Marshall J, Dylewski J. Evolution of a Simple Sore Throat. Poster. American College of Osteopathic Internists; Oct 2012; Orlando, FL. Marshall J, Axelband J. A Stubborn Spleen: It’s a Terrible Predicament. Poster. American College of Osteopathic Internists; Oct 2012; Orlando, FL. Marshall J; Poster. American College of Osteopathic Internists. Show Me the Marrow: Babesiosis Masquerading as Myelodysplastic Syndrome; Oct 2012; Orlando, FL. Menhaji K, Perdomo J, Gallagher T, Quiros R, Arastu M, Longo S. An Unusual Presentation of the “Great Masquerader.” Poster. American Association of Clinical Endocrinologists 23rd Annual Scientific and Clinical Congress; May 2014; Las Vegas, NV. Migliore F and Ruggeri C. Varicella Vasculopathy. Poster. American College of Osteopathic Internists Meeting; Oct 2013. Patel H, Ruggeri C. A Case of the Elevated LFTs. Poster. American College of Osteopathic Internists; Oct 2012; Orlando, FL. Perdomo J, Longo S, Polimera H, Fioravanti G, Arastu M. Endogenous ACTH-dependent Cushing Syndrome and Refractory Hypokalemia Caused by Gastric Adenocarcinoma. Poster. American Association of Clinical Endocrinologists 23rd Annual Scientific and Clinical Congress; May 2014; Las Vegas, NV. Perdomo J. To Drink or NOT to Drink: That is the Question. Poster. ICE/ENDO 2014; June 2014; Chicago, Illinois. Polimera H, Gallagher T, Perdomo J, Hurlbutt T, Leh D. Creptio of the Diem American College of Physicians PA Eastern Region Abstract and Poster Competition 2013; Nov 2013; Scranton, PA. Polimera H, Gallagher T, Perdomo J, Leh D. Creptio of the Diem. Poster Finalist. American College of Physician National Meeting; April 2014. Polimera H, Shaik S, Leh D, Arastu M. A Stroke of Bad Luck. Poster. ENDO 2013; June 2013.

Polimera H, Silparshetty S, Aradhya M, Gajanana D, Amedeo E, Sugathan P. Does Ultrafiltration for Acute Decompensated Heart Failure by Aquapheresis Increase Bleeding Risk? Poster. American College of Cardiology 61st Annual Scientific Session; March 2012; Chicago, IL. Polimera H. Respiratory failure in an Immunocompromised Patient: An alternative Approach to this Enigma. New York Thoracic Society Meeting; Spring 2013. Shaik S, Abichandari A, Arastu M, Gayner R. A Case of Hypokalemic Hypertension…Primum Non Nocere. Poster. American Association of Clinical Endocrinologists 22nd Annual Scientific and Clinical Congress; May 2013; Phoenix, AZ. Shaik S, Dhamdhere M, Arastu M, Leh D. All in the Family. Poster. ENDO 2013; June 2013. Shaik S, Kazi H, Bhatt B, Arastu M. An Incidental Pituitary Adenoma with Intact LH Hypersecretion. Poster. American Association of Clinical Endocrinologists 21st Annual Scientific and Clinical Congress; May 2012; Philadelphia, PA. Shaik S, Kazi H, Ender P. A New Twist on a Known Side-Effect of Piperacillin-Tazobactam. Poster. National Meeting of the American College of Physicians Resident Abstract Competition; April 2012. Shaik S, Kazi H, Leh D. Do Age and Gender Correlate Significantly with Dyslipidemia? Poster. The American Association of Clinical Endocrinologists 21st Annual Scientific and Clinical Congress; May 2012; Philadelphia, PA. Shaik S, Polimera H, Arastu M, Fioravanti G. Treatment of Anaphylaxis Unmasks Another Life-threatening Condition - Pheochromocytoma. Poster. ENDO; June 2013. Shaik S, Polimera H, Arastu M, Gayner R, Fioravanti G, Raghu P. An Ounce of Prevention: The Importance of Calcium and Vitamin D Supplementation Prior to Using Denosumab. Poster. American Association of Clinical Endocrinologists 22nd Annual Scientific and Clinical Congress; May 2013; Phoenix, AZ. Smith E, Ruggeri C, Perez-Acosta M. End of Life Planning and Outpatient Residency Clinics: Can They Coexist? Poster. American College of Osteopathic Internists; Oct 2012; Orlando, FL.

Traub D, Shirani S and Stahlnecker D. Presentation. Seventh Annual Cardiology Update for the Practitioner at DeSales University; 2011; Center Valley, PA. Trivedi H, Dylewski J, Pursell R, Snyder R. Alkaline Water â&#x20AC;&#x201C; An Alternative to Oral Bicarbonate Supplementation in CKD? Poster. National Meeting of the National Kidney Foundation; April 2013. Trivedi H, Ruggeri C, Mundorff J, Stoltzfus, J. Overlooked and Underrated: The Importance of Mental Health Illness in the Clinic. Poster. American College of Osteopathic Internists; Oct 2012; Orlando, FL. FACULTY APPOINTMENTS Susan Sefcik, MD: Member of the Academic Alliance for Internal Medicine (AAIM) Survey Committee (2006-2010) and the AAIM Diversity Committee (2010-2014). Cara Ruggeri, DO: Member of the Research Committee of the American College of Osteopathic Internists. Gloria Fioravanti, DO: Reviewer for Various Subsections of the Medical Knowledge Self-Assessment Program (MKSAP) MKSAP 15- Cardiology, MKSAP 16- Neurology, Infectious Diseases, MKSAP 17 (to be released) Pulmonary.

RESEARCH.SLUHN.ORG | 73

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION 74

PROGRAM ACHIEVEMENTS At the Southside Medical Center, which is the site of the continuity clinic for the Internal Medicine Residency Program, St. Luke’s has received NCQA Diabetes Recognition for 2006-2015, 2015-2018 and NCQA Heart/Stroke Recognition for 2009-2016. The Southside Medical Center participated with community partners and the St. Luke’s Community Health Department last year in a grant-funded program from the American Cancer Society - “Making Strides Against Breast Cancer.” This work was awarded second prize in the Annual St. Luke’s Quality Awards Program. Residents are involved in multiple hospital-wide committee initiatives focused on improving patient care and patient safety. GASTROENTEROLOGY: PUBLICATIONS Adesina A, Rammohan G, Jeanmonod R. Retrograde Gastro-Jejunostomy Tube Migration. Case Reports in Emergency Medicine. Dec 2014; 2014:738506. doi: 10.1155/2014/738506 Mudalel ML, Dave KP, Hummel JP, Solga SF. N-acetylcysteine Treats Intravenous Amiodarone Induced Liver Injury. World Journal of Gastroenterology. March 2015; 21(9):2816-9. doi: 10.3748/wjg.v21.i9.2816.

Reichert J, Hlavinka, P, Stoltzfus, J (2014). Risk of Hemorrhage in Patients with Chronic Liver Disease and Coagulopathy Receiving Pharmacologic Venous Thromboembolism Prophylaxis. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. Oct 34(10), 1043-1049. doi: 10.1002/phar.1464. Solga SF. Breath Volatile Organic Compounds for the Gut-fatty Liver Axis: Promise, Peril, and Path Forward. World Journal of Gastroenterology. July 2014; 20(27): 9017-25. doi: 10.3748/wjg.v20.i27.9017. Solga SF, Mudalel M, Spacek LA, Lewicki R, Tittel FK, Loccioni C, Russo A, Ragnoni A, Risby TH. Changes in the Concentration of Breath Ammonia in Response to Exercise: a Preliminary Investigation. Journal of Breath Research. Sept 2014; 8(3): 037103. doi: 10.1088/17527155/8/3/037103. Solga SF, Mudalel M, Spacek LA, Lewicki R, Tittel F, Loccioni C, Russo A, Risby TH. Factors Influencing Breath Ammonia Determination. Journal of Breath Research. Sept 2013; 7(3): 037101. doi: 10.1088/17527155/7/3/037101. Solga SF, Mudalel ML, Spacek LA, Risby TH. Fast and Accurate Exhaled Breath Ammonia Measurement. Journal of Visualized Experiments. June 2014;(88). doi: 10.3791/51658.

INFECTIOUS DISEASES: FACULTY PUBLICATIONS Cohen MS, Cipriano A, Stawicki SP, Firstenberg MS, Papadimos TJ. What’s New In Critical Illness & Injury Science: The Decades-Long Quest for a Valid Prognostic Sepsis Biomarker Continues. International Journal of Critical Illness & Injury Science. Oct-Dec 2014; 4(4): 275-7. doi: 10.4103/2229-5151.147517.

Doshi N, Mount K, Cook C, Stawicki S, Frazee E, Personett H, Schramm G, Arnold H. Comparison of Intravenous Colistin with and without Aerosolized Colistin for Multidrug Resistant Gram-negative Pneumonia in Critically Ill Patients. Critical Care Medicine. Dec 2012; 40(12): 1-328. doi: 10.1097/01.ccm.0000425121.82919.3a Morrison J, Zweitzig D, Riccardello N, Rubino J, Axelband J, Sodowich B, Kopnitsky M, O’Hara SM, Jeanmonod R. Analysis of Clinical Data from a Molecular Diagnostic Feasibility Study Highlights the Utility for Rapid Blood Stream Infection Detection. American Journal of Emergency Medicine. 2014: 32(6): 511-516. doi: 10.1016/j. ajem.2014.01.046 Nelson D, Jeanmonod R. Bezold Abscess: A Rare Complication of Mastoiditis American Journal of Emergency Medicine. Nov 2013; 31(11): 1626.e3-4. doi: 10.1016/j.ajem.2013.06.036. Stawicki SP, Firstenberg MS, Lyaker MR, Russell SB, Evans DC, Bergese SD, Papadimos TJ. Septic Embolism in the Intensive Care Unit. International Journal of Critical Illness and Injury Science. Jan 2013; 3(1):58-63. doi: 10.4103/2229-5151.109423.

Zweitzig DR, Riccardello NM, Morrison J, Rubino J, Axelband J, Jeanmonod R, Sodowich BI, Kopnitsky MJ, O’Hara SM. Measurement of Microbial DNA Polymerase Activity Enables Detection and Growth Monitoring of Microbes from Clinical Blood Cultures. PLoS One. Oct 2013;8(10): e78488. doi: 10.1371/journal.pone.0078488. INFECTIOUS DISEASES: FACULTY PRESENTATIONS Brainard A, Alcock J, Watts D, Stoltzfus J. A Comparison of Bacterial Colony Forming Units in Water Bottles and Hydration Bags Among Outdoor Enthusiasts. Presented at the St. Luke’s Hospital Research Forum; June 2008; Bethlehem, PA.

RESEARCH.SLUHN.ORG | 75

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Neurosciences The St. Luke’s Center for Neuroscience provides expert care of conditions of the nervous system. Under the leadership of Neurosurgery Section Chief Daniel K. O’Rourke, MD, FACS, the center offers specialized services for patients with brain tumors, intracranial aneurysms, epilepsy, multiple sclerosis, spine conditions, normal pressure hydrocephalus, chronic pain and movement disorders. Additionally, St. Luke’s neurologists and neurosurgeons actively conduct clinical research. Along with other advanced procedures, St. Luke’s offers deep brain stimulation (DBS) surgery. Functional neurosurgeon Dr. Steven Falowski, the first physician in the region to perform the surgery in 2011, has since performed more than 100 DBS procedures. Today, St. Luke’s DBS program ranks among the top 10 percent nationally in new patient DBS implants and remains the only such program in the region. Continuing its role as a pioneer of neuroscience research, St. Luke’s University Health Network is participating in the Sunburst™ (Success Using Neuromodulation with Burst) clinical study to test the effectiveness of the Prodigy™ neurostimulator, which delivers closely spaced pulses of electrical energy to a patient’s spinal cord to manage chronic pain. St. Jude Medical, Inc., a global medical device company, selected St. Luke’s as one of only 20 hospitals in the country to participate in the study and named Dr. Falowski as one of the investigators. He is working closely with Scott Loev, DO, Director of Pain Medicine at St. Luke’s Spine and Pain Associates. Dr. Falowski also serves on the board of directors for the North American Neuromodulation Society, the largest society dealing with spinal cord stimulation and neuromodulative procedures.

RadioSurgery system to a ‘frameless’ format, obviating the need for a rigid headframe to be affixed to the patient during focused, non-invasive radiation treatments — the only Center in the region to offer this innovation. The Radiosurgical team has been very proactive in adopting such new technologies as well as helping improve the techniques used to treat patients, and is presenting part of this work at the International Stereotactic RadioSurgery conference in Yokohama, Japan. St. Luke’s Neurosurgical Associates are the only regional neurosurgical practice enrolled in the National Neurosurgery Quality Outcomes Database (N2QOD). National surgical outcomes data is collected for patients undergoing cervical and lumbar surgeries to better understand their impact on quality of life and daily function. Dr. Don Zhang, MD, FRCSC and Dr. Doron Rabin, MD, FRCSC, neurosurgeons with special interest in complex spine surgery, routinely review this data and compare local and national outcomes. This information is used to guide and track initiatives that aim to improve the quality of inpatient and outpatient care for neurosurgical spine patients at St. Luke’s University Health Network.

St. Luke’s Brain & Spine Tumor Center provides the region’s only patient-centered multidisciplinary clinic for primary and metastatic diseases of the brain and spine. Under the direction of Hugh D. Moulding, MD, PhD, the center gives the patient an opportunity to consult with a multidisciplinary team of doctors from neurosurgery, radiation therapy and medical oncology at one time and one location. This multi-disciplinary group is involved in several national multi-center clinical trials, making these treatment options and opportunities available to their patients. In addition, the Center recently upgraded its Stereotactic

St. Luke’s DBS program ranks among the top 10 percent nationally in new patient DBS implants and remains the only such program in the region.

FACULTY PUBLICATIONS Balakrishnan V, Jeanmonod R. Two Episodes of Ventriculoperitoneal Shunt Migration in a Patient with Idiopathic Intracranial Hypertension.Â Case Reports in Emergency Medicine. 2014; 2014: 280793. doi:10.1155/2014/280793. Deer TR, Mekhail N, Petersen E, Krames E, Staats P, Pope J, Saweris Y, Lad SP, Diwan S, Falowski S, Feler C, Slavin K, Narouze S, Merabet L, Buvanendran A, Fregni F, Wellington J, Levy RM. The Appropriate Use of Neurostimulation: Stimulation of the Intracranial and Extracranial Space and Head for Chronic Pain. Neuromodulation. Aug 2014; 17(6): 551-570. doi:10.1111/ner.12215. Falowski S, Byrne R. Corpus Callosotomy with the CO2 Laser Suction Device: A Technical Note. Stereotactic and Functional Neurosurgery. 2012; 90(3): 137-40. doi:10.1159/000336337. Falowski S., Ghods AJ, Bakay RA. Displacement of a Deep Brain Stimulator Lead during Placement of an Additional Ipsilateral Lead. Neuromodulation. Jan-Feb 2013; 16(1): 41-4; discussion 44-45. doi: 10.1111/j.1525-1403.2012.00500.x.

RESEARCH.SLUHN.ORG | 77

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION 78

Falowski S, Ooi YC, Smith A, Verhargen Metman L, Bakay RA. An Evaluation of Hardware and Surgical Complications with Deep Brain Stimulation Based on Diagnosis and Lead Location. Stereotactic and Functional Neurosurgery. 2012; 90(3): 173-180. doi: 10.1159/000338254.

Moulding HD, Elder JD, Lis E, Lovelock DM, Zhang Z, Yamada Y and Bilsky MH. Local Disease Control After Decompressive Surgery and Adjuvant High Dose Single Fraction Radiosurgery for Spine Metastases. Journal of Neurosurgery: Spine. July 2010; 13(1): 87-93. doi: 10.3171/2010.3.SPINE09639.

Falowski S., Sharan A. A Review on Spinal Cord Stimulation. Journal of Neurosurgical Sciences. Dec 2012; 56(4): 287-298.

Moulding HD and MH Bilsky. Metastases to the Craniocervical Junction. Neurosurgery. 2010; 66(3) supplement: 113-8.

Falowski SM, Wallace D, Kanner A, Smith M, Rossi M, Balabanov A, Ouyang B, Byrne RW. Tailored Temporal Lobectomy for Medically Intractable Epilepsy: Evaluation of Pathology and Predictors of Outcome. Neurosurgery. Sept 2012; 71(3): 703-709; discussion 709. doi: 10.1227/NEU.0b013e318262161d.

Wu C, Sperling MR, Falowski SM, Chitale AV, WernerWasik M, Evans JJ, Andrews DW, Sharan AD. Radiosurgery for the Treatment of Dominant Hemisphere Periventricular Heterotopia and Intractable Epilepsy in a Series of Three Patients. Epilepsy & Behavior Case Reports. Nov 2012; 7;1: 1-6. doi:10.1016/j.ebcr.2012.10.004.

Kazi R, Kazi H, Ruggieri C, Ender PT. Eosinophilic Meningitis Secondary to Intravenous Vancomycin. Journal of Pharmacy Practice. June 2013; 26(3): 261-263. doi: 10.1177/0897190012452310.

ABSTRACTS Song X, Deb N, Moulding H, Xue T. A Study of RapidArc SBRT Spine Treatment Plans. 2011. The American Academy of Pain Medicine.

Obstetrics & Gynecology The Department of Obstetrics & Gynecology has a rich tradition of research and innovation. Under the leadership of Dr. James A. Airoldi, the department continues to be a clinical research hub for St. Luke’s University Health Network. Faculty members in multiple sections of the department devote their efforts to the tripartite mission of patient care, education of students and residents and clinical research. St. Luke’s provides the full spectrum of obstetrical and gynecological care for all stages of life beginning with birth. Each year physicians deliver more than 3,900 babies at St. Luke’s hospitals and are able to manage complex pregnancies, labors and deliveries. The Neonatal Intensive Care Units at both St. Luke’s Bethlehem and Allentown campuses are designed to provide a high level of care for babies and families, offering the latest technology and developmental techniques. St. Luke’s embraces parental involvement and in 2014 was recognized as offering the only March of Dimes Neonatal Intensive Care Unit (NICU) Family Support Program in the Lehigh Valley. A regional leader in managing expectant mothers with diabetes, St. Luke’s Perinatal Centers offer a complete management program for pregnant women who have or have developed diabetes or for non-pregnant women with diabetes who are contemplating a pregnancy in the future. Gynecological services include general care and a full complement of gynecologic specialists through St. Luke’s University Health Network Women’s Services and our affiliated private practice physicians. These include specialists in urogynecology, gynecological surgery and gynecological cancer treatment. The St. Luke’s University Hospital in Allentown is an AAGL Center of Excellence in Minimally Invasive Gynecology (COEMIG). The distinction recognizes hospitals that provide exceptional minimally invasive gynecologic surgical care and are dedicated to continuously improving health care quality and patient safety. This broad range of patient care provides excellent, hands-on learning experiences for students. Also, residents in Obstetrics & Genecology participate actively in scholarly activities and quality improvement projects under the guidance of Dr. James Anasti, Residency Program Director. In the last five years, faculty members and residents have presented more than 25 abstracts at national and international scientific conferences including meetings of the American College of Obstetricians and Gynecologists, the American Society of Reproductive Medicine, the Endocrine Society, the Society of Gynecologic Oncologists and the International Gynecologic Cancer Society. These presentations have generated important national accolades such as a top research award at the annual meeting of the American College of Obstetricians and Gynecologists.

RESEARCH.SLUHN.ORG | 79

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Cornu JN, Peyrat L, Skurnik A, Ciofu C, Lucente VR, Haab F. Ajust Single Incision Transobturator Sling Procedure for Stress Urinary Incontinence: Results after 1-year Follow-up. The International Urogynecology Journal. Sept 2013; 23(9): 1265-70. Crete JE, Anasti JN. Diagnosis of Gestational Diabetes Mellitus: Can We Avoid the Glucose Challenge Test? The Journal of the American Association of Nurse Practitioners. June 2013; 25(6): 329-33. Dewdney SB, Jiao Z, Roma AA, Gao F, Rimel BJ, Thaker PH, Powell MA, Massad LS, Mutch DG, Zighelboim I. The Prognostic Significance of Lymphovascular Space Invasion in Laparoscopic Versus Abdominal Hysterectomy for Endometrioid Endometrial Cancer. European Journal of Gynaecological Oncology. 2014; 35(1): 7-10.

During that time, members of the Obstetrics & Gynecology Department have authored or coauthored more than 35 peer-reviewed publications accepted by specialty and sub-specialty journals. Physicians in the urogynecology and gynecologic oncology sections are active members of national collaborative research organizations and run multiple clinical trials to benefit their patients. Many St. Lukeâ&#x20AC;&#x2122;s physicians sit on national boards and editorial boards of high impact national journals. They have also earned regional and national recognitions in patient care such as multiple Patientsâ&#x20AC;&#x2122; Choice Awards, Compassionate Doctors Awards and being named among the Top Doctors in their sub-specialties. PUBLICATIONS Airoldi J, Greco L, Lopez S, Trinidad M. The risk of Asymptomatic Intrauterine Infection Based on Cervical Length and Gestational Age. American Journal of Obstetrics & Gynecology. Jan 2013; 208(1): S218-S219. do1: http://dx.doi.org/10.1016/j.ajog.2012.10.673. Airoldi J. Practice Bulletin No. 135: Second-Trimester Abortion. Obstetrics & Gynecology; June 2013; 121(6): 1394-1406. doi: 10.1097/01.AOG.0000431056.79334.cc

Iglesia CB, Hale DS, Lucente VR. Laparoscopic Sacrocolpopexy Versus Transvaginal Mesh for Recurrent Pelvic Organ Prolapse. International Urogynecology Journal. March 2013; 24(3): 363-70. Garg G, Gao F, Wright JD, Hagemann AR, Zighelboim I, Mutch DG, Powell MA. The Risk of Lymph Node Metastasis with Positive Peritoneal Cytology in Endometrial Cancer. International Journal of Gynecological Cancer. Jan 2013; 23(1): 90-7. Gonzalez Rios AR, Anasti JN, Merola J, Nunemacher K. A Search for Novel Risk Factors for Obstetric Trauma. The American Journal of Obstetrics & Gynecology. May 2014; 123 Suppl 1: 54S. Grigsby PW, Zighelboim I, Powell MA, Mutch DG, Schwarz JK. In Vitro Chemoresponse to Cisplatin and Outcomes in Cervical Cancer. Gynecological Oncology. July 2013; 130(1): 188-91. Hagemann AR, Novetsky AP, Zighelboim I, Gao F, Massad LS, Thaker PH, Powell MA, Mutch DG, Wright JD. Phase II Study of Bevacizumab and Pemetrexed for Recurrent or Persistent Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer. Gynecological Oncology. Dec 2013; 131(3): 535-40.

Jambusaria LH, Murphy M, Lucente VR. One-Year Functional and Anatomic Outcomes of Robotic Sacrocolpopexy Versus Vaginal Extraperitoneal Colpopexy With Mesh. Female Pelvic Medicine & Reconstructive Surgery. Sept 2014. [Epub ahead of print] PubMed PMID: 25185594. Kuroki LM, Zhao Q, Jeffe DB, Powell MA, Hagemann AR, Thaker PH, Massad LS, Mutch DG, Zighelboim I. Disclosing a Diagnosis of Cancer: Considerations Specific to Gynecologic Oncology Patients. The American Journal of Obstetrics & Gynecology. Nov 2013; 122(5): 1033-9. Lucente V, Murphy M, Saiz C. Vaginal Prolapse Repair: Suture Repair Versus Mesh Augmentation: A Urogynecology Perspective. Urologic Clinics of North America. Aug 2013; 39(3): 325-33. Mach CM, Kim J, Soibam B, Creighton CJ, Hawkins SM, Zighelboim I, Goodfellow P, Gunaratne PH, Odunsi K, Salem PA, Anderson ML. Novel MicroRNAs Regulating Proliferation and Apoptosis in Uterine Papillary Serous Carcinomas. Cancer Letters. July 2013; 335(2): 314-22. doi: 10.1016/j.canlet.2013.02.043. Myers JR, Gillier CM, Kriner RM, Constant AD, Wetzel LA, Anasti JN. The Use of Abdominal Binders in Patients Undergoing Cesarean Delivery: A Prospective Randomized Controlled Trial. The American Journal of Obstetrics & Gynecology. May 2014; 123 Suppl 1: 160S. Novetsky AP, Kuroki LM, Massad LS, Hagemann AR, Thaker PH, Powell MA, Mutch DG, Zighelboim I. The Utility and Management of Vaginal Cytology After Treatment for Endometrial Cancer. The American Journal of Obstetrics & Gynecology. Jan 2013; 121(1): 129-35. Novetsky AP, Smith K, Babb SA, Jeffe DB, Hagemann AR, Thaker PH, Powell MA, Mutch DG, Massad LS, Zighelboim I. Timing of Referral for Genetic Counseling and Genetic Testing in Patients with Ovarian, Fallopian Tube, or Primary Peritoneal Carcinoma. International Journal Gynecological Cancer. July 2013; 23(6): 1016-21. Novetsky AP, Thompson DM, Zighelboim I, Thaker PH, Powell MA, Mutch DG, Goodfellow PJ. Lithium Chloride and Inhibition of Glycogen Kinase 3B as a Potential Therapy for Serous Ovarian Cancer. International Journal of Gynecological Cancer. Feb 2013; 23(2): 361-6. Novetsky AP, Zighelboim I, Guntupalli SR, Ioffe YJ, Kizer NT, Hagemann AR, Powell MA, Thaker PH, Mutch DG, Massad LS. A Phase II Trial of a Surgical Protocol to Decrease the Incidence of Wound Complications in Obese Gynecologic Oncology Patients. Gynecological Oncology. Aug 2014; 134(2): 233-7. Novetsky AP, Zighelboim I, Thompson DM, Powell MA, Mutch DG, Goodfellow PJ. Frequent Mutations in the RPL22 Gene and its Clinical and Functional Implications. Gynecological Oncology. March 2013; 128(3): 470-4. Rekuc E, Chaya R, Airoldi J. Are There Third Trimester Ultrasound Findings that Could Identify Late Onset Gestational Diabetes? American Journal of Obstetrics & Gynecology. Jan 2011; 204(1): S116-S117. Roberts CA, Lucente VR. Three-year Outcomes of Vaginal Mesh for Prolapse: A Randomized Controlled Trial. The American Journal of Obstetrics & Gynecology. March 2014; 123(3): 664-5.

RESEARCH.SLUHN.ORG | 81

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION 82

Rosenblatt P, Schumacher J, Lucente V, McNevin S, Rafferty J, Mellgren A. A Preliminary Evaluation of the TOPAS System for the Treatment of Fecal Incontinence in Women. Female Pelvic Medicine & Reconstructive Surgery. May-June 2014; 20(3): 155-62. Sides C, Trinidad MC, Heitlinger L, Anasti J. Crohn Disease and the Gynecologic Patient. The American Journal of Obstetrics & Gynecology Survey. Jan 2013; 68(1): 51-61. Stawicki SP, Papadimos TJ. Challenges in Managing Amniotic Fluid Embolism: An Up-to-date Perspective on Diagnostic Testing with Focus on Novel Biomarkers and Avenues for Future Research. Current Pharmaceutical Biotechnology. 2014; 14(14): 1168-1178. Tha T, Trinidad MC, Anasti JN. Incidental Gynecologic Findings on Computed Tomography Scans Done in the Emergency Department. The American Journal of Obstetrics & Gynecology. May 2014; 123 Suppl 1: 33S.

Zighelboim I, Mutch DG, Knapp A, Ding L, Xie M, Cohn DE, Goodfellow PJ. High frequency Strand Slippage Mutations in CTCF in MSI-positive Endometrial Cancers. Human Mutation. Jan 2014; 35(1): 63-5. Zighelboim I, Wright JD, Gao F, Case AS, Massad LS, Mutch DG, Powell MA, Thaker PH, Eisenhauer EL, Cohn DE, Valea FA, Alvarez Secord A, Lippmann LT, Dehdashti F, Rader JS. Multicenter Phase II Trial of Topotecan, Cisplatin and Bevacizumab for Recurrent or Persistent Cervical Cancer. Gynecological Oncology. 2013 Jul;130(1): 64-8. doi: 10.1016/j.ygyno.2013.04.009. Zutshi P, Paredes I, Winn H, Stoltzfus J, Anasti J. Short Interval Between Pregnancies: A Search for Modifiable Risk Factors. The American Journal of Obstetrics & Gynecology. May 2014; 123 Suppl 1:112S. doi: 10.1097/01. AOG.0000447058.02212.f0. PubMed PMID: 24769947.

ABSTRACTS & PRESENTATIONS Faouod L, Trinidad C, Anasti JN. Impact of Uniform Counseling on Intrauterine Device Continuation Rate. 61st Annual Clinical Meeting of the American College of Obstetricians and Gynecologists; 2013. Balogach A, Althauser C, Martin M, Walp S. Noncoached Pushing in the Second Stage of Labor. Journal of Gyncologic and Neonatal Nursing. June 2012; 41(s1): S136-S137. Myers J, Giller C, Kriner R, Anasti JN: The Effect of Abdominal Binder on Pain and Distress in Post Cesarean Section Patients. 62nd Annual Clinical Meeting of the American College of Obstetricians and Gynecologists; April 2014; Chicago, IL. Nunemaker K, Martin M, Anasti JN, Pai A. Building Better Teams Utilizing TeamSTEPPS and E-Learning Technology. Agency for Healthcare Research and Quality; November 2013; Washington, DC. Rios-Gonzales A, Nunemaker K, Merola JC, Anasti J. A Search for Novel Risk Factors for Obstetrical Trauma; 62nd Annual Clinical Meeting of the American College of Obstetricians and Gynecologists; April 2014; Chicago, IL. Rios-Gonzales A, Vessio EM, Anasti JN. The Importance of Reproductive History in Women Undergoing Bariatric Surgery. International Society of Endocrinology and the Endocrine Society Annual Meeting; June 2014; Chicago, IL. Smith T, Eberhardt M. A Comparison of Confirmed Intrauterine Pregnancy by Ultrasound in Patients with Vaginal Bleeding in Early Pregnancy with HCG Levels Above and Below 2000. Poster. American College of Emergency Physicians Scientific Assembly Seattle; October 2013; Washington, DC. Trinidad C, Meyers J, Nunnamaker K, Merola J, Anasti JN. Staff Perceptions of a Culture of Safety: Impact of a Comprehensive OB Patient Safety Program. 61st Annual clinical Meeting of the American College of Obstetrians and Gynecologists; 2013. Trinidad C, Rios A, Anasti JN. Screening Urine Culture with Mixed Contaminants in Pregnancy: A Risk Factor for GBS Colonization? 61st Annual clinical Meeting of the American College of Obstetrians and Gynecologists; May 2013; New Orleans, LA. Trinidad C, Tau T, Anasti JN. Incidental Gynecologic finding on CT Scans from the Emergency Room Patients. 62nd Annual Clinical Meeting of the American College of Obstetrians and Gynecologists; April 2014; Chicago, IL. Trinidad M, Gonzalez R, Anasti J. Screening Urine Culture with Mixed Contaminants in Pregnancy: A Risk Factor for GBS Colonization? Poster Presentation. 61st Annual Clinical Meeting of the American College of Obstetricians and Gynecologists; May 2013; New Orleans, LA. Zutshi P, Paredes I, Winn H, Stoltzfus J, Anasti J. Short interval between pregnancies: A search for modifiable risk factors 62st Annual Clinical Meeting of the American College of Obstetrians and Gynecologists; April 2014; Chicago, IL.

RESEARCH.SLUHN.ORG | 83

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Oncology St. Luke’s University Health Network is committed to being one of the best places to receive comprehensive cancer care. Last year St. Luke’s provided cancer services to more than 2,900 new oncology patients. The Network has three comprehensive outpatient cancer centers in Allentown, Bethlehem and Easton (Anderson Campus), and also provides cancer services in Quakertown, Coaldale, East Stroudsburg and Warren County, NJ. Under the direction of Lee B. Riley, MD, PhD, FACS, Network Chairman, Department of Oncology, St. Luke’s provides nationally recognized cancer care, participates in numerous clinical trials and conducts extensive research. The cancer team includes fellowship-trained cancer experts specializing in surgical oncology, medical oncology, radiation oncology, gynecologic oncology, thoracic-oncology, urologic-oncology and neurosurgical oncology. Committed to advancing the field of oncology, St. Luke’s oncologists frequently present at national conferences and contribute to well-respected peer-reviewed journals. St. Luke’s earned national Three-Year Accreditation with Commendation as an Integrated Network Cancer Program (INCP) through 2016 from the Commission on Cancer of the American College of Surgeons (ACS CoC). St. Luke’s was one of only two health care networks in the state of Pennsylvania to receive this distinction and one of only 51 health care networks nationwide. St. Luke’s Cancer Center maintains its current level clinical excellence while embracing new advances and leading-edge technology to give patients the best possible care.

Active in cancer research, St. Luke’s Clinical Trials Office supports clinical investigators, enabling them to bring patients a variety of clinical research trials, quality service, education and support. The Oncology Clinical Trials Team offers studies sponsored by industry pharmaceutical companies, governmentsponsored studies through NCI’s National Clinical Trials Network (NCTN) such as ECOG-ACRIN and NRG, as well as investigator-initiated trials (IITs). Originating within the network, some of these multisite trials involve St. Luke’s as the lead coordinating center. In 2014, more than 10 percent of network cases were enrolled in clinical trials. Within the last two years St. Luke’s has increased the number of trials opened per year by more than 50 percent. St. Luke’s has been a nationally recognized center for melanoma for over a decade, starting with Dr. Riley’s introduction of clinical trials with CancerVax, high dose interleukin 2, anti-CTLA4 and peptide vaccines. The program continues to thrive under the direction of Dr. Sanjiv Agarwala, MD, Chief of Medical Oncology.

“ We’re using science to better understand melanoma and then using that knowledge to create targeted treatments. It truly is an exciting time to be involved in melanoma research and treatment.” — Sanjiv Agarwala, MD

St. Luke’s provides nationally recognized cancer care, participates in numerous clinical trials and conducts extensive research.

During the past five years, Dr. Riley and Dr. Agarwala have both authored papers published in the New England Journal of Medicine. An internationally recognized melanoma specialist, Dr. Agarwala has brought promising melanoma studies to residents of the Lehigh Valley and surrounding areas. St. Luke’s Cancer Center became the first center in the world to offer a new Phase II oncolytic viral therapy for advanced melanoma from the Japanese innovative biotechnology company, Takara Bio, Inc. and recently enrolled its first patient. Using biotechnology, viruses are converted into therapeutic agents to destroy cancers. This promising therapy uses the injectable strain of the Herpes simplex virus, HF10, to destroy cancer cells and produce an anti-tumor immune response. Since the study is Phase II, patients still receive the standard-of-care therapy for advanced melanoma, the FDAapproved drug ipilimumab, along with this new viral treatment. St. Luke’s was also the first in the region to offer ipilimumab to patients prior to FDAapproval as part of an expanded access clinical research. Through several clinical trials, many of which St. Luke’s was a major contributor, ipilimumab has been shown to help some people with advanced melanomas live longer by targeting CTLA-4, a protein that suppresses the T-cell immune response, thus leading to its FDA approval in 2011. In radiation oncology, St. Luke’s was the first hospital in the state to use robotic surgery for prostate cancer and Intrabeam’s intraoperative radiation therapy (IORT) for breast cancer. Designated a Center of Excellence by the American College of Radiology, St. Luke’s Regional Breast Center was the first facility of its kind in the region to provide higher-level breast imaging exclusively. Advanced imaging technology offered at the St. Luke’s Regional Breast Center includes Automated Breast Ultrasound (ABUS), which provides a clearer, more accurate evaluation of dense breast tissue. Advanced imaging technology is available at other sites, including the St. Luke’s Women’s Imaging Center in the West End Medical Center, Allentown, the location of the new low dose 3D mammography system — GE’s SenoClaire® breast tomosynthesis. It uses a low-dose, short X-ray sweep around the compressed breast. The 3D technology separates

RESEARCH.SLUHN.ORG | 85

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

the tissues to reduce overlapping of structures. St. Luke’s University Health Network facilities participate annually in the National Cancer Data Base (NCDB) through the Cancer Registry and utilize the Cancer Program Practice Profile Reports (CP3R) as a mechanism to assess and monitor concordance with standards of care. SLUHN facilities’ Accountability and Quality Improvements Measure rates surpassed the Commission on Cancer’s expected performance rates. Also, the Network promotes programs to screen individuals for cancer and assess risk of developing the disease. St. Luke’s Lung Cancer Screening Program was developed under the leadership of thoracic surgeon Dr. William Burfeind. More than 1,000 patients have been screened to date through St. Luke’s, resulting in 250 positive scans. Eleven cases of cancer were identified and seven had curative resections. St. Luke’s implemented a Lynch Syndrome Surveillance Program that involves universal screening for malignant lesions in patients at risk. The test, performed on endometrial and/or colonic tumors, helps direct the appropriate patients to genetic counseling and potential testing for the genetic mutations involved. The Network’s infusion centers implemented a Distress Thermometer Screening for all new cancer patients undergoing treatment. This assures that every new patient starting chemotherapy has their psychosocial needs addressed and refers them to our Cancer Care Counselors if needed. Other 2014 Highlights and Accomplishments Include: • St. Luke’s University Health Network was recognized for achieving the highest level of quality and patient safety in Radiation Oncology, earning a three-year accreditation from the American College of Radiology (ACR). • Philanthropic support allowed St. Luke’s to purchase Faxitron technology for the St. Luke’s Allentown Campus. The device enables clinicians to biopsy tissue right in the Operating Room; the sample never leaves the sterile field for transfer to a lab to be read. This decreases the amount of time a patient must remain under anesthesia. A leader in medical education, the Network offers the St. Luke’s Hospice and Palliative Medicine Fellowship to recruit outstanding primary care physicians to train in the evaluation and management

of clinical issues in end-of-life care. Fellows complete rotations in Radiation Oncology and Surgical Oncology, as well as participate in the Tumor Board. PUBLICATIONS Agarwala S, Eggermont A, O’Day S, Zager J. Metastatic Melanoma to the Liver: A Contemporary and Comprehensive Review of Surgical, Systemic and Regional Therapeutic Options. Cancer. March 2014; 120(6): 781-789. doi: 10.1002/cncr.28480. Agarwala SS, Guo J, Buzaid AC. Systematic Treatment of Cutaneous and Mucosal Melanoma. Chinese Clinical Oncology. Sept 2014; 3(3): 25. doi: 10.3978/j.issn.23043865.2014.08.07. Agarwala SS. An Update on Pegylated IFN-a2b for the Adjuvant Treatment of Melanoma. Expert Review of Anti-infective Therapy. Nov 2012; 12(11): 1449-1459 doi: 10.1586/era.12.120. Agarwala SS. Intralesional Therapy for Advanced Melanoma: Promise and Limitation. Current Opinion in Oncology. March 2015; 27(2): 151-156. doi: 10.1097/ CCO.0000000000000158. Ascierto P, Schadendorf D, Berking C, Agarwala SS, van Herpen C, Queirolo P, Blank C, Hauschild A, Beck JT, St-Pierre A, Niazi F, Wandel S, Peters M, Zubel A, Dummer R. MEK162 for Patients with Advanced Melanoma Harbouring NRAS or Val600 BRAF Mutations: a Non-Randomised, Open-Label Phase 2 Study. The Lancet Oncology. March 2013; 14(3): 249-256. doi: 10.1016/S1470-2045(13)70024-X. Berry M, Hanna J, Tong B, Burfeind W, Harpole D, D’Amico T, Onaitis M. Risk Factors for Morbidity After Lobectomy for Lung Cancer in Elderly Patients. Annals of Thoracic Surgery. 2009; 88: 1093-1099. doi: http:// dx.doi.org/10.1016/j.athoracsur.2009.06.012. Buzaid AC, Agarwala SS, Hauschild A, Atkins M. Algorithm for the Management of Metastatic Cutaneous Melanoma. Chinese Clinical Oncology. 2014; 3(3): 32. doi: 10.3978/j.issn.2304-3865.2014.07.01. Fecher L, Agarwala SS, Hodi FS, Weber JS. Ipilimumab and Its Toxicities: A Multidisciplinary Approach. The Oncologist. June 2013; 18(6): 733-743. doi: 10.1634/ theoncologist.2012-0483.

Kaufman H, Kirkwood J, Hodi FJ, Agarwala SS, Amatruda T, Bines S, Clark J, Curti B, Ernstoff M, Gajewski T, Sharfman W, Sondak V, Sosman J, Steel S, Tarhini A, Thompson J, Titze J, Urba W, White R, Atkins M. The Society for Immunotherapy of Cancer Consensus Statement on Tumour Immunotherapy for the Treatment of Cutaneous Melanoma. Nature Reviews Clinical Oncology. Oct 2013; 10(10): 588-598. doi: 10.1038/ nrclinonc.2013.153. Leong S, Mihm M, Murphy G, Hoon D, Kashani-Sabet M, Argarwala S, Zager Z, Hauschild A, Sondak V, Guild V, Kirkwood J. Progression of Cutaneous Melanoma: Implications for Treatment. Clinical and Experimental Metastasis. Oct 2012; 29(7): 775-796. doi: 10.1007/ s10585-012-9521-1. Maison-Blanche P, Dakhil S, Baron A, Rottey S, Millard F, Daugaard G, Machiels J, Conkright W, Sharma S, Soetekouw P, Yachnin J, Sengeløv L, Van Veldhuizen P, Argarwala S, Sémiond P, Chadjaa M, Shen L, Wade J. An Open-label Study to Investigate the Cardiac Safety Profile of Cabazitaxel in Patients with Advanced Solid Tumors. Cancer Chemotherapy and Pharmacology. June 2014; 73(6): 1241-1252. doi: 10.1007/s00280-014-2460-6. Nashan D, Reuter K, Mohr P, Argarwala S. Understanding and Managing Interferon-aRelated Fatigue in Patients with Melanoma. Melanoma Research. Dec 2012; 22(6): 415-423. doi: 10.1097/CMR.0b013e328358d98c. Nemunaitis JJ, Linette GP, Hamid O, Agarwala SS, Starodub A, Sun L, Lebel F, Barrett JA, Lewis J. Regulated Intratumoral Expression of IL-12 as a Basis for Combination Therapy in Melanoma. Journal of Translational Medicine. 2014; 12(Suppl 1): O11. doi: 10.1186/1479-5876-12-S1-O11. Salen P, Porter M, Watts D, Stoltzfus J, Lynch A, Michaelis C, Melanson S. A Randomized, Double-blind, Sham-controlled Trial Comparing Two Screening Devices for Radiation Contamination. American Emergency Medicine Journal. Sept 2010; 17(9):1020-1023. doi: 10.1111/j.1553-2712.2010.00861.x. Thompson J, Argarwala S, Smithers BM, Ross M, Scoggins C, Coventry B, Neuhaus S, Minor D, Singer J, Wachter E. Phase 2 Study of Intralesional PV-10 in Refractory Metastatic Melanoma. Annals of Surgical Oncology. July 2015; 22(7): 2135-2142. doi: 10.1245/s10434-014-4169-5. Wong S, Balch C, Hurley P, Argarwala S, Akhurst T, Cochran A, Cormier J, Gorman M, Kim T, McMasters K, Noyes RD, Lynn M, Schuchter L, Matias E, Valsecchi M, Weaver D, Lyman G. Sentinel Lymph Node Biopsy for Melanoma: American Society of Clinical Oncology and Society of Surgical Oncology Joint Clinical Practice Guideline. Journal of Clinical Oncology. Aug 2012; 30(23):2912-2918. doi: 10.1200/JCO.2011.40.3519. Zhou G, Stoltzfus J, Houldin A, Parks S, Swan, B (2010). Knowledge, Attitudes and Practice Behaviors of Oncology Advanced Practice Nurses Regarding Advanced Care Planning for Patients with Cancer. Oncology Nursing Forum. 2010; 37(6): E400 – E410. doi: 10.1188/10. ONF.E400-E410.

American College of Surgery Commission on Cancer (ACoS CoC) CoC Accreditation

RESEARCH.SLUHN.ORG | 87

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Orthopaedic Surgery The St. Luke’s Department of Orthopaedic Surgery is advancing the field by bringing advanced treatments to the Lehigh Valley and surrounding areas, providing orthopaedic education and sharing their knowledge with colleagues around the country through national publications and conferences. Under the leadership of Dr. William G. De Long, Jr., Chief of Orthopaedics, St. Luke’s physicians and staff provide outstanding diagnosis, treatment and rehabilitation for patients experiencing a wide variety of musculoskeletal disorders and injuries. St. Luke’s Bone and Joint Institute, with locations in Quakertown, at St. Luke’s Hospital – Anderson Campus (Easton), and at St. Luke’s Hospital – Warren Campus (Phillipsburg, NJ), aligns leading physicians and therapists to deal with all aspects of orthopaedic conditions. St. Luke’s offers many advanced procedures including anterior approach hip replacement and minimally invasive sacroiliac (SI) joint fusion procedure. Committed to medical education, St. Luke’s offers an orthopaedic surgery residency. This rigorous, five-year training prepares residents to be leaders in the orthopaedic community. Dr. De Long was invested as the Charles and Anna Kasych Family Chair of Orthopaedic Surgery at St. Luke’s University Health Network. The endowed chair advances orthopaedic research, education and clinical care at St. Luke’s. PUBLICATIONS Anakwenze OA, Kancherla VK, Iyengar J, Ahmad CS, Levine WN. Posterolateral Rotatory Instability of the Elbow. The American Journal of Sports Medicine. Feb 2014; 42(2): 485-491. doi: 10.1177/0363546513494579. Avery D, Matullo K. Dedicated Orthopaedic Surgical Teams: Influence on Operating Room Efficiency. The Journal of Hand Surgery. Jan 2014; 39(1): 108-110. Avery D, Matullo K. Distal Radius Traction Radiographs: Interobserver ad Intraobserver Reliability Compared with Computed Tomography. The Journal of Bone and Joint Surgery. April 2014; 96(7): 582-588.

Avery DM, Carolan, GF. Traumatic Obturator Hip Dislocation in a 9-year-old Boy. The American Journal of Orthopaedics. Sept 2013; 42(9): E81-83. Banzhof JA, Robbins CE, Ven AV, Talmo CT, Bono JV. Femoral Head Dislodgement Complicating Use of a Dual Mobility Prosthesis for Recurrent Instability: A Case Report. March 2013; 28(3): 543.e1-3. doi: 10.1016/j.arth.2012.08.020. Caggiano N, Matullo K. Midcarpal Instability: Review and Treatment Options. Orthopedic Clinics of North America. Jan 2014; 45(1): 129-140. Cross D and Matullo K. Dual Carpal and Cubital Tunnel Endoscopic Release: Safety and Efficacy. Hand. March 2014; 9(1): 43-47. doi: 10.1007/s11552-013-9552-3. Cross D and Matullo K. Kienbock’s Disease. Orthopedic Clinics of North America. Jan 2014; 45(1): 141-152. Heckman DS, McCoy AJ, Spritz CE, Garrett WE. Intercondylar Synovial Septum in Two Patients with Nail-patella Syndrome. The Journal of Knee Surgery. Dec 2013; Supple1: S107-111. Heckman DS, McCoy AJ, Spritzer CE, Garrett WE. Intercondylar Synovial Septum in Two Patients with Nail-patella Syndrome. The Journal of Knee Surgery. Dec 2013; 26 Suppl 1:S107-11. doi:10.1055/s-0032-1324809. Kancherla VK, Del Gaizo DJ, Paprosky WG, Sporer SM. Utility of Trephine Reamers in Revision Hip Arthroplasty. The Journal of Arthroplasty. Jan 2014; 29(1): 210-213. doi: 10.1016/j.arth.2013.04.009. Matullo K, Dennison D. Acute Fractures, Nonunions, Malunions: Forearm, Hand and Upper Extremity Textbook. ASSH. 2013.

St. Luke’s physicians and staff provide outstanding diagnosis, treatment and rehabilitation for patients.

Matullo K, Shin A. ORIF of Scaphoid Fractures. In: Atlas of Essential Orthopaedic Procedures. AAOS. Chapter 41. June 2013. Mellon M, De Long WG, Rehman S. Distal Femur Fractures. In: Ilyas, AM, Rehman S, ed. Contemporary Surgical Management of Fractures and Complications. New Delhi, India: Jaypee Brothers Medical Publishing (P) Ltd; March 2013: 737-765. Riboh JC, Heckman DS, Glisson RR, Moorman CT III. Shortcuts in Arthroscopic Knot Tying: Do They Affect Knot and Loop Security? The American Journal of Sports Medicine. July 2012; 40(7): 1572-1577. doi: 10.1177/0363546512446676. Selhi HS, Mahindra P, Yamin M, Jain D, De Long WG, Singh J. Outcome in Patients with an Infected Non-union of the Long Bones Treated with a Reinforced Antibiotic Bone Cement Road (RABC). Journal of Trauma. 2012; 26(3). Sokunbi G, Cahill P, Pumberger M. Adolescent Idiopathic Scoliosis – Surgical Outcomes. European Musculoskeletal Review. 2012; 7(1): 54-57.

PRESENTATIONS Avallone N. Concussion Management in the High School and College Athlete. St. Luke’s and East Stroudsburg University Emergency Action Summit, Warren Hills Regional High School; June 2014; Washington, NJ. Avallone N. Shoulder Instability in the Athlete. Sports Medicine Lecture Series. Morristown Medical Center; Dec 2013; Morristown, PA. Avery D, Matullo K. Dedicated Orthopaedic Surgical Teams: Influence on Operating Room Efficiency. Poster. Residents’ Research Day, St. Luke’s University Hospital, June 12; 2014; Bethlehem, PA. Avery D Matullo K. Distal Radius Traction Views: Inter- and Intraobserver Reliability Compared to Computed Tomography. “Best” Poster. Orthopaedic Research Society; March 2014; New Orleans, LA.

RESEARCH.SLUHN.ORG | 89

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION 90

Avery D, Matullo K. Distal Radius Traction Views: Inter- and Intraobserver Reliability Compared to Computed Tomography. Poster. American Society for Surgery of the Hand; Oct 2013; San Francisco, CA.

Avery D. Operating Room Turnover Time in Hand Surgery: Dedicated Orthopaedic Staff Increases Efficiency. Poster. Residents’ Research Day; St. Luke’s University Hospital; June 2014; Bethlehem, PA.

Avery D, Matullo K. Distal Radius Traction Views: Inter- and Intraobserver Reliability Compared to Computed Tomography. Podium Presentation. Resident Research Day, St. Luke’s University Hospital; June 2013; Bethlehem, PA.

Avery D. Surgeon Determined Visualization in Shoulder Arthroscopy: A Randomized Blinded Controlled Trial Comparing Irrigation Fluid with and without Epinephrine. Poster. The American Association of Nurse Anesthetists National Meeting; May 2014; Hollywood, FL.

Avery D. Autologous Chondrocyte Implantation. Oral. Orthopaedic Grand Rounds, St. Luke’s University Hospital; May 2013; Bethlehem, PA. Avery D. Distal Radial Traction Views. Poster. Orthopaedic Research Society Annual Meeting; March 2014; New Orleans, LA. Avery D. Distal Radius Traction Views: Inter- and Intra-observer Reliability with Comparison to Computed Tomography. Presentation. St. Luke’s University Hospital Research Day; June 2013; Bethlehem, PA. Avery D. Injuries of the UCL of the Thumb. Oral. Orthopaedic Grand Rounds, St. Luke’s University Hospital; May 7, 2014; Bethlehem, PA.

Caggiano N, Auchter S, and Matullo K. Outpatient and Surgical Case Volume Before and After Adoption of an Electronic Medical Record System. Poster. Philadelphia Orthopaedic Trauma Symposium; June 2014; Philadelphia, PA. Caggiano N, Avery DM, Matullo, K. The Incidence of Supraspinatus Weakness in Patients with Lateral Epicondylitis. Poster. St. Luke’s University Hospital, Resident Research Day; June 2014; Bethlehem, PA. Caggiano N, Fegley M, and Matullo K. Patients’ Preferences Regarding the Delivery of Healthcare with Modern Technology. Poster. Philadelphia Orthopaedic Trauma; June 2014; Philadelphia, PA.

Caggiano N. Concurrent Ipsilateral Supraspinatus Weakness in Patients with Lateral Epicondylitis. Poster. Residents’ Research Day, St. Luke’s University Hospital; June 12, 2014; Bethlehem, PA. Cross D, Matullo K. Optimal Fusion Angle for Thumb IP Joint Arthrodesis. The American Society for Surgery of the Hand meeting; Oct 2013; San Francisco, CA. Cross D, McGowan S, Matullo K. Optimal Fusion Angles of the Thumb IP Joint: A Functional Study. Oral. American Association for Surgery of the Hand; Jan 2014; Kauai, HI. Cross D, Ross D, Matullo K. Concomitant Endoscopic Carpal and Cubital Tunnel Release: Safety and Efficiency. Poster. American Society for Surgery of the Hand; Oct 2013; San Francisco, CA. De Long W. (co-chair). Spanning Ex-Fix Strategies/ORIF Plateau: Options, Section 1. Orthopaedic Trauma Association 28th Annual Meeting and Comprehensive Fracture Course for Residents; Oct 2012; Minneapolis, MN. De Long W. Arthroscopy as an Adjunct in Fracture Treatment: When It Can Help. Lecturer/ Panelist. 5th Annual Philadelphia Orthopaedic Trauma Symposium, Physician Assistant Session; June 2013; Philadelphia, PA. De Long W. Bone Morphogenetic Proteins and DBMs. Philadelphia Orthopaedic Trauma Symposium, Temple University; June 2014; Philadelphia, PA. De Long W. Damage Control Orthopaedics. Department of Orthopaedic Surgery Grand Rounds Lecture, University of Medicine and Dentistry of New Jersey, School of Osteopathic Medicine; Oct 2013; Stratford, NJ. De Long W. Difficult Proximal Femur Fractures: What Would You Do? Panelist. 5th Annual Philadelphia Orthopaedic Trauma Symposium; June 2013; Philadelphia, PA. De Long W. Evidence for Staged Management of Periarticular Fractures; Who Really Needs a Spanning Ex Fix? Philadelphia Orthopaedic Trauma Symposium, Temple University; June 2014; Philadelphia, PA. De Long W. Periarticular “Anatomic” Plates. Moderator. Philadelphia Orthopaedic Trauma Symposium, Temple University; June 2014; Philadelphia, PA. De Long W. Proximal Femur Fractures. Moderator. 5th Annual Philadelphia Orthopaedic Trauma Symposium; June 2013; Philadelphia, PA. De Long W. The Effect of Weight on Orthopaedic Conditions. Oral. St. Luke’s Third Annual Bariatric Symposium. DeSales University; November 2013; Center Valley, PA. De Long W. The History of Orthopaedic Traumatology: Where We Began and Where We Are Headed. Keynote Lecture. 5th Annual Philadelphia Orthopaedic Trauma Symposium; June 2013; Philadelphia, PA. De Long W. Traction Pin Insertion and Setup Techniques. Lab Moderator/Panelist. 5th Annual Philadelphia Orthopaedic Trauma Symposium, Physician Assistant Session; June 2013; Philadelphia, PA.

RESEARCH.SLUHN.ORG | 91

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

De Long W. Trauma Session. Moderator. Pennsylvania Orthopaedic Society Meeting 2014 Spring Scientific Meeting: Treating Musculoskeletal Disease in an Aging Population; April 2014; Hershey, PA.

Kancherla V, Matullo K. The Use of Electrodiagnostic Studies in the Diagnosis of Ulnar Nerve Entrapment. Oral. American Academy of Orthopedic Surgeons; March 2013; Chicago, IL.

De Long WG. Anterior Approach to THA. Oral. Orthopaedic Grand Rounds, St. Luke’s University Hospital; Sept 2013; Bethlehem, PA.

Kancherla V, Matullo K. Utility of Electrodiagnostic Studies in the Diagnosis of Ulnar Nerve Entrapment. Podium Presentation. American Academy of Orthopaedic Surgeons; March 2013; Chicago, IL.

Dickson C. Calcium Intake and Exercise Habits of College-aged Women. Poster. St. Luke’s University Hospital Research Day; June 2013; Bethlehem, PA. Dickson C. Free Tissue Transfer in the Mangled Lower Extremity. Poster. St. Luke’s University Hospital Research Day; June 2013; Bethlehem, PA. Dickson C. Pediatric Trauma. Oral. Orthopaedic Grand Rounds, St. Luke’s University Hospital; Feb 2013; Bethlehem, PA.

Kancherla V. Utility of Electrodiagnostic Studies in the Diagnosis of Ulnar Nerve Entrapment. E-Poster. The 67th Annual Meeting of the American Society for Surgery of the Hand; Sept 2012; Chicago, IL.

Dickson C. Syndesmotic Injuries. Oral. Orthopaedic Grand Rounds, St. Luke’s University Hospital; June 4, 2014; Bethlehem, PA.

Kancherla V. Utility of Trephine Reamers in Revision Hip Arthroplasty. Oral Presentation. American Academy of Orthopedic Surgeons; March 2013; Chicago, IL.

George B. Bachoura R, Culp R. Psychosocial Factors in Patients Diagnosed with Saddle Syndrome of the Hand. American Academy of Orthopaedic Surgeons Annual Meeting; March 2013; June 2013; Philadelphia, PA.

Matullo K. Are There Downsides to a Plate for Every Fracture? Philadelphia Orthopaedic Trauma Symposium; June 2014; Philadelphia, PA.

George B. Perilunate Dislocations. Oral. Orthopaedic Grand Rounds, St. Luke’s University Hospital; Nov 2013; Bethlehem, PA.

Matullo K. Complex Elbow Fractures: Application and Usage of a Hinged Elbow External Fixator. Clinical Instructor. Philadelphia Orthopaedic Trauma Symposium; June 2013; Philadelphia, PA.

Gibson B. Arthroscopic Treatment of Hip Pain. Pennsylvania Physical Therapy Association Meeting; St. Luke’s Hospital; March 2013; Easton, PA. Gibson B. Current Trends in Arthroscopic Rotator Cuff Repair. Orthopaedic Grand Rounds, St. Luke’s University Hospital; Nov 2012; Bethlehem, PA. Gibson B. St. Luke’s Sports Medicine Round-Up. ESPN Radio Broadcast, Nassau Broadcasting; April 2013; Easton, PA. Heckman D. Prevention and Treatment of Common Orthopaedic Running Injuries. St. Luke’s Half Marathon Race Expo, St. Luke’s University Hospital Health Network; April 2014; Allentown, PA. John-David Black, MD. Multi-disciplinary Implications of Pelvic Trauma. Oral. Trauma-Ortho Grand Rounds, St. Luke’s University Hospital; Sept 2013; Bethlehem, PA.

Kancherla V. Spinal Infections: Diagnosis and Management. Oral. Orthopaedic Grand Rounds St. Luke’s University Hospital; March 5, 2014; Bethlehem, PA.

Matullo K. Complex Hand Trauma: What To Do in the Emergency Room: An Update. Philadelphia Orthopaedic Trauma Symposium; June 2014; Philadelphia, PA. Matullo K. Complex Hand Trauma: What to do in the Emergency Room. Clinical Instructor. Philadelphia Orthopaedic Trauma Symposium; June 2013; Philadelphia, PA. Matullo K. Kancherla, V. Utility of Electrodiagnostic Studies in the Diagnosis of Ulnar Nerve Entrapment. E-poster. American Society for Surgery of the Hand; Sept 2012; Chicago, IL. Nicholas Caggiano, MD. Ulnar-Sided Wrist Pain. Oral. Orthopaedic Grand Rounds, St. Luke’s University Hospital; Jan 2014; Bethlehem, PA.

Nwachuku C. Geriatric Acetabular Fractures. Orthopaedic Grand Rounds, St. Luke’s University Hospital; Sept 2012; Bethlehem, PA. Nwachuku C. Periprosthetic Fractures. Pennsylvania Orthopaedic Society Spring Scientific Meeting: Treating Musculoskeletal Disease in an Aging Population; April 2014; Hershey, PA. Nwachuku C. Surgical Techniques for Posterior Malleolus and Plafond Fixation. Orthopaedic Trauma Symposium; June 2013; Philadelphia, PA. Puccio S. Back Pain. Annual Contemporary Issues in Trauma Conference, Arts Quest/ Steel Stacks; Oct 2012; Bethlehem, PA. Puccio S. SI Joint: Diagnosis and Treatment. Orthopaedic Grand Rounds, St. Luke’s University Hospital; May 2013; Bethlehem, PA. Reddy C. Treatment of Shoulder Dislocations. Oral. Orthopaedic Grand Rounds, St. Luke’s University Hospital; Sept 2013; Bethlehem, PA. Sokunbi G, Cho W, Essig D, Faloon M, Sokunbi G, King A, Cunningham M, Boachie-Adjei O. The Importance of Sagittal Stable Vertebrae in Adolescent Idiopathic Scoliosis (AIS) Surgery. E-Poster. 19th International Meeting on Advanced Spine Techniques (IMAST); July 2012; Istanbul, Turkey. Sokunbi G. Cervical Radiculopathy: Current Treatment Options. Oral. Orthopaedic Grand Rounds, St. Luke’s University Hospital; Oct 2013; Bethlehem, PA. Sokunbi G., Faloon M, Cho W, Ross T, Cunningham M, Rawlins B, Boachie-Adjei O. Perioperative Complications of AxiaLIF in Long Fusions to the Sacropelvis in Adult Spinal Deformity. E-Poster. 19th International Meeting on Advanced Spine Techniques (IMAST); July 2012; Istanbul, Turkey. Jul 2012; 40(7):1572-7. Doi: 10.1177/0363546512446676. ORTHOPAEDICS: SPORTS MEDICINE PUBLICATIONS & ABSTRACTS Burkey S, Fedor P, Stromski C, Jeanmonod R. Airway Management of the Helmeted Athlete: Standard ETI vs. LMA. AMSSM Research Workshop; Aug 2009; Minneapolis, MN. Clinical Journal of Sports Medicine. 20(2): 136-137, 2010.

St. Luke’s is the only Own the Bone-certified facility in the region.

RESEARCH.SLUHN.ORG | 93

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION 94

Other OPHTHALMOLOGY

OTOLARYNGOLOGY / EAR-NOSE-THROAT

The doctors at St. Luke’s are experienced in diagnosing and treating eye and vision disorders. Under the direction of Dr. Marilyn McDonald, more than 20 ophthalmologists perform advanced eye procedures including laser eye surgery and sutureless small incision cataract extraction and treat Behcet’s syndrome, cataracts, diabetic eye problems, eye injuries, glaucoma and macular degeneration.

To provide patients with the best treatment, otolaryngologists at St. Luke’s University Health Network are the first in the region to offer a wide variety of new technologies. These include the use of drug-eluting stents in sinus surgery and robotic surgery in treating cancers of the head and neck. Additionally, all physicians pursue continuing medical education and many participate in clinical research to offer the most up-to-date care possible.

St. Luke’s Retina Center is the only hospital-based retina center in the Lehigh Valley. It specializes in the testing and treatment of conditions relating to the retina and the vitreous body, such as diabetic retinopathy and macular degeneration. PUBLICATIONS

Under the direction of Dr. David Yen, St. Luke’s more than 15 otolaryngologists perform routine and advanced ear, nose and throat procedures. Conditions treated include acoustic neuroma, dizziness and vertigo, Meniere’s disease, sinusitis, esophagus fisorders and thyroid conditions.

Shields JA, Shields CL, Kimmel AS, Eagle RC Jr. Contralateral Blindness from Chiasmal Extension of Unsuspected Choroidal Melanoma. Ophthalmic Plastic and Reconstructive Surgery. Sept 2004; 20(5): 384-7.

To provide patients with the best treatment, otolaryngologists at St. Luke’s University Health Network are the first in the region to offer a wide variety of new technologies.

Pain & Palliative Care Services St. Luke’s University Health Network is committed to enhancing pain management and palliative care through treatment, consultation and education. Ric A. Baxter, MD, FAAHPM, Chairman, Department of Pain Medicine and Palliative Care, leads the specially trained team of doctors, advance practitioners, nurses and social workers. In providing patient care, the St. Luke’s Pain and Palliative Care Services team assesses the physical, social, emotional and spiritual needs of patients coping with a life-limiting illness. The team focuses on improving quality of life by helping patients emphasize what brings value to their lives. In addition, the team provides consultative services to health care professionals. This includes guidance on providing advanced acute post-operative pain management of patients who receive peripheral nerve blocks/catheters and/or neuraxial analgesics. Also, they advise staff on pain control of opioid-naive patients experiencing uncontrolled post-operative pain and acute-on-chronic pain management of opioid-tolerant, post-operative patients. In addition, Dr. Baxter serves as program director of the Hospice/Palliative Medicine Fellowship, St. Luke’s Family Medicine Residency Program. PUBLICATIONS Adolph MD, Frier KA, Stawicki SP, Gerlach AT, Papadimos TJ. Palliative Critical Care in the Intensive Care Unit: A 2011 Perspective. International Journal of Critical Illness & Injury Science. 2011; 1(2): 147-153. doi: 10.4103/2229-5151.84803. DeVader T, Albrecht R, Reiter M. Initiating Palliative Care in the Emergency Department. Journal of Emergency Medicine. Nov 2012; 43(5): 803-810. doi: 10.1016/j.jemermed.2010.11.035. Papadimos TJ, Gafford EF, Stawicki SP, Murray MJ. Diagnosing Dying. Anesthesia and Analgesia. 2014; 118(4): 879-882. doi: 10.1213/ANE.0000000000000043. PRESENTATIONS Baxter, Ric MD, Harrold, J. MD, MPH. Diagnosis, Prognosis and Medical Direction: Decisions and Documentation by the Hospice Medical Director and IDG. PHN/NHPCO Joint Seminar: 9/12/2014 Clarion, PA; 10/14/2014 Allentown, PA; 11/4/2014 Lancaster, PA. Baxter, Ric MD. Palliative Care in the ICU. 3rd Annual Pulmonary & Critical Care Update for Practitioners; Sept 2014; Center Valley, PA. DeVader T, Jeanmonod R. Perceived Barriers to Providing Palliative Care in the Emergency Department. St. Luke’s Research Symposium 2010. Poster. American Academy of Emergency Medicine Scientific Assembly; 2011; Orlando, FL. DeVader T, Jeanmonod R. Do Emergency Medicine Residents Retain Key Concepts in Hospice and Palliative Care After an Educational Intervention? Oral. Society for Academic Emergency Medicine 2011 Annual Meeting; June 2015; Boston, MA.

RESEARCH.SLUHN.ORG | 95

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION 96

Pathology The pathologists of St. Luke’s University Health Network use the tools of laboratory science to provide clinical specialists with diagnostic information essential in the diagnosis of many diseases, which challenge physicians in every specialty of medical practice. St. Luke’s pathologists are integral members of both diagnostic and clinical research teams by providing details about the etiology, pathogenesis and pathophysiology of many diseases. Dr. David W. Anderson is St. Luke’s Chairman of the Pathology Department and Temple University School of Medicine Clinical Professor of Pathology. Dr. Anderson leads the department’s team of nine pathologists in applying the latest knowledge and technologies in the diagnosis and treatment of many diseases. In 2014, the department completed more than 2 million clinical laboratory tests and nearly 36,000 routine and state-of-the-art testing of tissue samples.

Central in the practice of pathology is the study and interpretation of morphologic expression of disease at organ, tissue, cellular and ultra-structural levels. The spectrum of research interests includes oncology, cardiology, rheumatology, traumatology and epidemiology. Most recently, Dr. Anderson has led his team in the participation of complex collaborative research focused on cancer and cardiac disease.

In 2014, the department completed more than 2 million clinical laboratory tests and nearly 36,000 routine and state-of-the-art testing of tissue samples.

PUBLICATIONS AND ABSTRACTS Li J, Nanda S, Longo S. Acute Pericarditis Induced Stress Cardiomyopathy. Acta cardiologica. June 2010; 65(3): 361-4. doi:10.2143/AC.65.3.2050358. Nanda S, Longo S, Arastu M. Unicuspid Aortic Valve, Hand Anomalies: A Heart-hand Syndrome. The American Journal of the Medical Sciences. March 2010; 339(3):296-9. doi:10.1097/MAJ.0b013e3181c5ba64. Nanda S, Longo S. Clinical Images: A Rare Presentation of Colonic Pseudoobstruction in CREST. Arthritis & Rheumatology. Dec 2010; 62(12):3836. doi:10.1002/art.27725. Nanda S, Patel NC, Bhatt SP, Mathiesen C, Castaldo J, Sharma SG, Longo S. Therapeutic Medical Hypothermia–A Multispecialty Approach. Recent Patents on Cardiovascular Drug Discovery. Nov 2010; 5(3): 212-22. Nanda S, Sharma S, Longo S. Catastrophic Rapid Onset Heparin-induced Thrombocytopenia - Victim of our Own Success. Acta cardiologica. 02/2010; 65(1):93-5. doi:10.2143/AC.65.1.2045897. Nanda S, Sharma S, Longo S. Superficial Siderosis - Mechanism of Disease: an Alternative Hypothesis. Annals of Clinical Biochemistry. May 2010; 47(Pt 3):275-8. doi:10.1258/acb.2010.009226. L. Riley, H. Nakijima, K. Balinger, D. Anderson. Abstract P2-06-04: Impact of genomic testing on chemotherapy utilization. Cancer Research. Dec 2012; 72(24 Supplement): P2-06-04-P2-06-04. doi:10.1158/0008-5472.SABCS12-P2-06-04 Samuel B, Fioravanti G, Smith A, Longo S, Axelband J. Nocardia as a Complication in a 30-year-old Immunocompromised Hispanic Woman. Laboratory Medicine. Oct 2014; 45(4): e166-9. doi:10.1309/LMCO0GIJWVJAMMDH. Sapino A, Roepman P, Linn SC, Snel MH, Delahaye LJ, van den Akker J, Glas AM, Simon IM, Barth N, de Snoo FA, van ‘t Veer LJ, Molinaro L, Berns EM, Wesseling J, Riley LB, Anderson D, Nguyen B, Cox CE. MammaPrint Molecular Diagnostics on Formalin-fixed, Paraffinembedded Tissue. The Journal of Molecular Diagnostics. March 2014; 16(2): 190-7. doi: 10.1016/j.jmoldx.2013.10.008. Sharma S, Nanda S, Longo S. Angiogenesis and the Heart. Recent Patents on Cardiovascular Drug Discovery. Oct 2010; 5(3): 171-176. doi:10.2174/157489010793351953. Sharma SG1, Nanda S, Longo S. Anti-angiogenic Therapy in Renal Cell Carcinoma. Recent Patents on Anti-cancer Drug Discovery. 2010 Jan; 5(1): 77-83.

RESEARCH.SLUHN.ORG | 97

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Pediatrics & Neonatology St. Luke’s Pediatrics Department is comprised of board-certified pediatricians and neonatologists, as well as expert advanced practitioners committed to caring for children and educating future pediatricians. The Neonatal Intensive Care Units at both St. Luke’s Bethlehem and Allentown campuses are designed to provide a high level of care for babies and families, offering the latest technology and developmental techniques. St. Luke’s embraces parental involvement and in 2014 was recognized as offering the only March of Dimes Neonatal Intensive Care Unit (NICU) Family Support Program in the Lehigh Valley.

Contact Information

St. Luke’s Inpatient Unit cares for children who need the acute care services of a hospital. In 2014, it provided children in the community with diagnostic services, treatment and well baby/child check-ups through its five outpatient locations, 10 general pediatric practices and three subspecialist practices.

Questions about research and clinical trials:

484-526-4873

Established patients:

Call individual office

Referral line for new patients:

Call individual office

Pediatric Endocrine:

484-526-7300

Pediatric GI:

484-526-7575

Pediatric Nephrology:

610-865-5888

KidsCare:

484-526-3060

Coopersburg Pediatrics:

484-526-7337

Pocono Pediatrics:

570-664-8750

ABW Pediatrics:

610-868-2007

Palmerton Pediatrics:

610-826-1166

Chaired by Dr. Jennifer Janco, the faculty of the St. Luke’s Pediatric Department represents a blend of clinical expertise, academics and personalized care delivery. The specialty physicians offer a broad range of difficultto-find and advanced clinical skills. They include: Dr. Pamela Abrams, a board-certified pediatric endocrinologist; Dr. Leo Heitlinger, a board-certified pediatric gastroenterologist with a lifetime certification in pediatric gastroenterology and Dr. Tecile Andolino, the only board-certified pediatric nephrologist in the Lehigh Valley. Dr. Dianne Jacobetz actively participates in medical student and resident driven research, including designing a pediatric specific history and physical form to improve quality of data collected during admissions and outcomes of infants born with meconium analysis positive for in utero alcohol exposure. Dr. Laurel Erickson-Parsons of the inpatient hospitalist team is heading the quality improvement project titled Improving community acquired pneumonia management jointly with the American Academy of Pediatrics. St. Luke’s is one of only 50 hospitals selected for this project.

The Neonatal Intensive Care Units at both St. Luke’s Bethlehem and Allentown campuses are designed to provide a high level of care for babies and families.

PUBLICATIONS Abrams P, Levitt Katz LE, Moore RH, Xanthopoulos MS, Bishop-Gilyard CT, Wadden TA, Berkowitz RI. Threshold for Improvement in Insulin Sensitivity with Adolescent Weight Loss. Journal of Pediatrics. Sept 2013; 163(3): 785-90. doi: 10.1016/j.jpeds.2013.04.003. Abrams P, Levitt Katz LE. Metabolic Effects of Obesity Causing Disease in Childhood. Current Opinion Endocrinology Diabetes and Obesity. Feb 2011; 18(1): 23-27. doi: 10.1097/ MED.0b013e3283424b37. Avery DM III, Carolan GF. Traumatic Obturator Hip Dislocation in a 9-year-old Boy. The American Journal of Orthopaedics. Sept 2013; 42(9): E81-3. Bhat V, Fojas M, Saslow JG, Shah S, Sannoh S, Amendolia B, Pyon K, Kemble N, Stahl G, Aghai ZH. Twice-weekly Fluconazole Prophylaxis in Premature Infants: Association with Cholestasis. Pediatrics International: Official Journal of the Japan Pediatric Society. Aug 2011; 53(4): 475-9. doi: 10.1111/j.1442-200X.2010.03286.x. Dumpa V, Adler B, Allen D, Bowman D, Gram A, Ford P, Sannoh S. Reduction in Central Line-Associated Bloodstream Infection Rates After Implementations of Infection Control Measures at a Level 3 Neonatal Intensive Care Unit. American Journal of Medical Quality. Nov 2014. pii: 1062860614557637. Katz LE, Gralewski KA, Abrams P, Brar PC, Gallagher PR, Lipman TH, Brooks LJ, Koren D. Insulin-like Growth Factor-I and Insulin-like Growth Factor Binding Protein-1 Are Related to Cardiovascular Disease Biomarkers in Obese Adolescents. Pediatric Diabetes. Dec 2014. doi: 10.1111/pedi.12242. Lightdale JR, Gremse DA, Heitlinger LA, Cabana M, Gilger MA, Gugig R, Lightdale JR, Hill ID.Â Gastroesophageal Reflux: Management Guidance for the Pediatrician. Pediatrics. May 2013; 131(5): e1684-1695. Gastroesophageal Reflux: Management Guidance for the Pediatrician. doi: 10.1542/peds.2013-0421.

RESEARCH.SLUHN.ORG | 99

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Milius EM, Papademetrious TR, Heitlinger LA. Retrospective Review of Propofol Dosing for Procedural Sedation in Pediatric Patients. The Journal of Pediatric Pharmacology and Therapeutics. July 2012; 17(3): 184-189. doi: 10.5863/1551-6776-17.3.246.

Abrams P. Complementary and Alternative Medicine for Diabetes. Grand Endocrinology Rounds, University of Pennsylvania School of Medicine; May 2012; Philadelphia, PA.

Sannoh S, Clones B, Munoz J, Montecalvo M, Parvez B. A Multimodal Approach to Central Venous Catheter Hub Care Can Decrease Catheter-related Bloodstream Infection. American Journal of Infection Control. Aug 2010; 38(6): 424-429. doi: 10.1016/j.ajic.2009.07.014.

Abrams P. Pediatric Adrenal Tumors. Grand Endocrinology Rounds, University of Pennsylvania School of Medicine; April 2011; Philadelphia, PA.

Thomas DW, Greer FR, Bhatia JJ, Abrams SA, Daniels SR, Schneider MB, Silverstein J, Stettler N, Thomas, DW, Grummer-Strawn L, Hubbard VS, Marchand V, Silverman BM, Soto V, Heitlinger LA, Baker RD Jr, Gremse DA, Gugig R, Lightdale JR, Byrne WJ, Cochran WJ, Euler AR, Heyman MB, Burrowes DL. Probiotics and Prebiotics in Pediatrics. Pediatrics. 2010; 126(6): 1217-1231. doi: 10.1542/peds.2010-2548.

Abrams P. Premature Puberty. Pediatric Grand Rounds, St. Luke’s University Health Network; Oct 2013; Bethlehem, PA.

Wicker L, Saslow J, Shah S, Bhat V, Sannoh S, Brandon E, Kemble N, Pyon K, Stahl G, Aghai ZH. The Effect of Comprehensive Infection Control Measures on the Rate of Late-onset Bloodstream Infections in Very Low-birth-weight Infants. American Journal of Perinatology. March 2011; 28(3): 227-232. doi: 10.1055/s0030-1268237. ABSTRACTS Abrams P, Koren D, Brar P, Gallagher P, Magge SN, Levitt Katz LE. Relationships Between IGF Axis Parameters, Inflammatory Markers, and Adipocytokines in Obese Adolescents. Poster. The Endocrine Society Meeting; June 2011; Boston, MA. Abrams P, Levitt Katz LE, Moore RH, Xanthopoulos MS, Lau J, Berkowtiz RI. Improvements in Insulin Sensitivity and Metabolic Syndrome During an Adolescent Weight Loss Trial. Poster and Audio Tour. American Diabetes Association Meeting; June 2012; Philadelphia, PA. Abrams P, MacMullen C, De Leon D, Stanley CA. A Case of Late-onset Hyperinsulinemic Hypoglycemia Worsened by Exercise. Poster. Pediatric Academic Society/Lawson Wilkins Pediatric Endocrine Society Meeting; May 2010; Vancouver, BC.

100

PRESENTATIONS

Abrams P. Pediatric Obesity. Family Medicine Grand Rounds, St. Luke’s University Health Network; Sept 2012; Bethlehem, PA.

Abrams P. Short Stature and Growth Failure. Family Medicine Grand Rounds, St. Luke’s University Health Network; April 2014; Bethlehem, PA. Abrams P. Type 1 Diabetes. Pediatric Education Day, St. Luke’s University Health Network; Oct 2012; Bethlehem, PA. Heitlinger LA. Faculty Member. The American Academy of Pediatrics National Conference and Exhibition; Oct 2013; Orlando, FL. Heitlinger LA. Faculty Member. The American Academy of Pediatrics National Conference and Exhibition; Oct 2014; San Diego, CA.

ACADEMIC APPOINTMENTS Dr. Pamela Abrams: Clinical Assistant Professor of Pediatrics, Temple University School of Medicine (2012-present), Philadelphia, PA. Dr. Lindy Cibischino: Teaching/clinical faculty for Temple, The Commonwealth Medical College, Kings College, DeSales and Arcadia. Dr. Leo Heitilnger: Temple University, Clinical Professor, (DeSales, PA program). A. North American Society for Pediatric Gastroenterology, Hepatology and Nutrition i. Professional Education Committee 2007-2010 ii. Maintenance of Certification Task Force, 2011-2012 iii. Public Affairs and Advocacy Committee, 2011-present iv. Finance Committee, 2012-present v. Foundation Board, 2014-present B. American Academy of Pediatrics i. Section of Gastroenterology, Hepatology and Nutrition, Chair, 2009-present ii. Specialty Medical Home Leadership Team, 2011-present iii. PA Chapter Board, 2014-present Dr. Sulaiman Sannoh: Assistant Clinical Professor of Pediatrics, Temple University School of Medicine, Philadelphia, PA. TEACHING APPOINTMENTS WITH TEMPLE UNIVERSITY AND DESALES Jennifer Janco, Dianne Jacobetz, Eyda Samuels, Laurel Erickson-Parsons, Maya Greenberg, Aram Yousef-Elmi, Alexandra Solosko, Alycia Walty, Tecile Andolino, Fatima Malik. HONORS/AWARDS Dr. Sulamain Sannoh: America’s Top Physician 2014 for Pediatric Neonatology, Consumer’s Research Council of America.

RESEARCH.SLUHN.ORG | 101

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Physical and Occupational Therapy and Speech Language Pathology St. Luke’s University Health Network offers a wide range of physical, occupational, speech and wellness programs. Therapists actively pursue clinical research and participate in the education of therapy students. Rehabilitation services are provided through two separate entities — the Inpatient Rehabilitation Department and Physical Therapy at St. Luke’s which provides outpatient services. INPATIENT REHABILITATION DEPARTMENT The Inpatient Rehabilitation Department of St. Luke’s University Health Network is committed to providing cost effective, client-centered and evidence-based therapy to individuals who have sustained physical, cognitive, communication, social and emotional disabilities as a result of aging, illness or injury. The goal of inpatient rehabilitation services is to prepare the patient to return to the next level of care whether that is home, home with home services, skilled nursing or acute rehabilitation services. Meanwhile, therapists support clinical research and participate in the education of students.

St. Luke’s 31-bed Acute Rehabilitation Center, located at the St. Luke’s University Hospital – Bethlehem, helps patients who have experienced a catastrophic illness or injury, such as brain injury, stroke, joint replacement, orthopaedic injury, amputation and heart disease. Specially trained therapists work with physicians and nurses to help patients re-learn or develop the skills to live as independently as possible after leaving the hospital. The Center offers intensive one-to-one inpatient rehabilitation and nursing services to patients requiring three or more hours of therapy by two or more of the rehabilitation disciplines. Patients are admitted after their hospitalization and then typically go home from there.

Under the direction of Michael Amory, OT, Network Director of Inpatient Rehabilitation, physical, occupational and speech therapists provide evaluation and treatment within SLUHN’s six hospitals. At St. Luke’s patient care is paramount and therapists evaluate and treat various patient populations including: • Bariatric • Cardiac • Critical Care • Neurological/Neurosurgical • Orthopaedic • Pediatric • Poly-trauma • Pulmonary

102

St. Luke’s 31-bed Acute Rehabilitation Center helps patients who have experienced a catastrophic illness or injury.

PHYSICAL THERAPY AT ST. LUKE’S (OUTPATIENT SERVICES) Under the direction of physical therapists Dennis and Judy Dougherty, approximately 175 clinical staff members provided 195,000 outpatient sessions (visits) in 2014. With more than 25 years of experience treating patients and operating practices in the Lehigh Valley, the Doughertys and their team are committed to providing high quality rehabilitative services close to home. Physical Therapy at St. Luke’s operates 24 outpatient rehabilitation locations in Bucks, Carbon, Lehigh, Monroe, Northampton and Schuylkill counties in Pennsylvania and Warren County in New Jersey. Physical Therapy at St. Luke’s has been successful in recruiting rehabilitation specialists skilled in advanced techniques to improve patients’ mobility, function and overall wellness. In fact, 85 percent of physical therapists are doctorally trained. In addition, the staff includes: • 13 board-certified orthopaedic clinical specialists • Four board-certified sports clinical specialists • A board-certified geriatric clinical specialist • A Fellow of the American Academy of Orthopaedic Manual Physical Therapists Therapists evaluate and treat various patient populations including: • Geriatric • Neurological/Neurosurgical • Orthopaedic/Spine • Pediatric • Sports • Women’s Health Beside patient care, St. Luke’s therapists are actively involved in research and work with physician specialists in many areas, including joints, heart and vascular, trauma, spine and pain. The therapy team also participates in several clinical studies. The Research Team consists of Stephen Kareha, PT, DPT, OCS, ATC, CMP, CSCS; Jeffrey Bays, PT, OCS, Cert MDT; Nikol Tews, PT, DPT, OCS, Cert MDT; Rett Holmes, PT, DPT, OCS, Cert MDT; Timothy Miller, PT, DPT, OCS, SCS, CSCS; and Mirella Deisher, OTR/L, OTD, CHT. Physical Therapy at St. Luke’s is committed to furthering professional education for both staff and students. Kareha, director of Physical Therapy Post-Graduate Education at St. Luke’s Physical Therapy and also adjunct faculty at Arcadia University, leads these efforts to facilitate learning and advancement of its clinical staff members while also providing educational opportunities and clinical experience for students pursuing careers in physical therapy, occupational therapy, speech therapy and audiology programs. Working under the supervision and guidance of an expert clinician, St. Luke’s offers learning opportunities in orthopaedic surgery observation, orthotic prescription and fabrication, audiology, and pediatric, occupational, vestibular, hand and aquatic therapies. In addition, Physical Therapy at St. Luke’s offers an orthopaedic residency program designed to provide physical therapists with advanced knowledge and skill training in the clinical environment. The curriculum enhances interprofessional collaboration and provides physical therapists with advanced training in orthopaedic examination, clinical decisionmaking and treatment skills. For more information, visit Physical Therapy at St. Luke’s.

RESEARCH.SLUHN.ORG | 103

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

HONORS/AWARDS Outcomes Excellence Awards: Focus on Therapeutic Outcomes, Inc. Outcomes Excellence Award – 2014 Q4 - Physical Therapy at St. Luke’s – Anderson Campus Focus on Therapeutic Outcomes, Inc. Outcomes Excellence Award – 2014 Q4 - Physical Therapy at St. Luke’s – Center Valley Focus on Therapeutic Outcomes, Inc. Outcomes Excellence Award – 2014 Q4 - Physical Therapy at St. Luke’s – Commons Focus on Therapeutic Outcomes, Inc. Outcomes Excellence Award – 2014 Q4 - Physical Therapy at St. Luke’s – Emmaus Focus on Therapeutic Outcomes, Inc. Outcomes Excellence Award – 2014 Q4 - Physical Therapy at St. Luke’s – Illick’s Mill Focus on Therapeutic Outcomes, Inc. Outcomes Excellence Award – 2014 Q4 - Physical Therapy at St. Luke’s – Northampton Focus on Therapeutic Outcomes, Inc. Outcomes Excellence Award – 2014 Q4 - Physical Therapy at St. Luke’s – Quakertown

Focus on Therapeutic Outcomes, Inc. Outcomes Excellence Award – 2014 Q2 - Physical Therapy at St. Luke’s – Emmaus Focus on Therapeutic Outcomes, Inc. Outcomes Excellence Award – 2014 Q2 - Physical Therapy at St. Luke’s – Illick’s Mill Focus on Therapeutic Outcomes, Inc. Outcomes Excellence Award – 2014 Q1 - Physical Therapy at St. Luke’s – Emmaus Focus on Therapeutic Outcomes, Inc. Outcomes Excellence Award – 2014 Q1 - Physical Therapy at St. Luke’s – Illick’s Mill Focus on Therapeutic Outcomes, Inc. Outcomes Excellence Award – 2013 Q4 - Physical Therapy at St. Luke’s – Emmaus Focus on Therapeutic Outcomes, Inc. Outcomes Excellence Award – 2013 Q4 - Physical Therapy at St. Luke’s – Illick’s Mill CONTACT INFORMATION

Focus on Therapeutic Outcomes, Inc. Outcomes Excellence Award – 2014 Q4 - Physical Therapy at St. Luke’s – Tilghman

Questions about research and clinical trials:

610-530-2363

Established patients:

484-526-5025

Focus on Therapeutic Outcomes, Inc. Outcomes Excellence Award – 2014 Q3 - Physical Therapy at St. Luke’s – Anderson Campus

Referral line for new patients:

484-526-5025

Focus on Therapeutic Outcomes, Inc. Outcomes Excellence Award – 2014 Q3 - Physical Therapy at St. Luke’s – Emmaus Focus on Therapeutic Outcomes, Inc. Outcomes Excellence Award – 2014 Q3 - Physical Therapy at St. Luke’s – Hellertown Focus on Therapeutic Outcomes, Inc. Outcomes Excellence Award – 2014 Q3 - Physical Therapy at St. Luke’s – Illick’s Mill Focus on Therapeutic Outcomes, Inc. Outcomes Excellence Award – 2014 Q3 - Physical Therapy at St. Luke’s – North

104

Focus on Therapeutic Outcomes, Inc. Outcomes Excellence Award – 2014 Q3 - Physical Therapy at St. Luke’s – Quakertown

Address where clinical trials and research are conducted: Central location: Tilghman Clinic (4136 W. Tilghman St., Allentown, PA 18104); Satellite locations: St. Luke’s North (153 Brodhead Rd, Bethlehem, PA 18017), Anderson Campus (1700 St. Luke’s Boulevard, Suite 201, Easton, PA 18045), Hellertown (2301 Cherry Lane, Hellertown, PA 18015), Illick’s Mill (1174 Illick’s Mill Rd, Bethlehem, PA 18017)

PUBLICATIONS Deisher M. “A Systems Change: Leading the Way to Meeting Health Needs.” Journal of Hand Therapy. July-September 2013; 26(3): 282-286. doi:10.1016/j.jht.2013.03.001. McClure P, Greenberg E, Kareha S. Evaluation and Management of Scapular Dysfunction. Sports Medicine and Arthroscopy Review. March 2012; 20(1): 39-48. doi: 10.1097/ JSA.0b013e31824716a8. McClure PW, Tate AR, Kareha S, Irwin D, Zlupko E. A Clinical Method for Identifying Scapular Dyskinesis: Part 1 Reliability. Journal of Athletic Training. March-April 2009; 44(2): 160-164. doi: 10.4085/1062-6050-44.2.160. Ojha HA, Snyder RS, Davenport TE. Direct Access Compared with Referred Physical Therapy Episodes of Care: a Systematic Review. Physical Therapy. Jan 2014; 94(1): 14-30. doi: 10.2522/ptj.20130096. Tate AR, McClure PW, Kareha S, Irwin D, Barbe M. A Clinical Method for Identifying Scapular Dyskinesis: Part 2 Validity. Journal of Athletic Training. March-April 2009; 44(2):165-173. doi: 10.4085/1062-6050-44.2.165. Tate AR, McClure PW, Kareha S, Irwin D. Effect of the Scapula Reposition Test on Shoulder Impingement Symptoms and Elevation Strength in Overhead Athletes. Journal of Orthopaedic and Sports Physical Therapy. 2008; 38(1): 4-11. doi: 10.2519/jospt.2008.2616. ABSTRACTS McClure P, Kareha S, Tate AR, Irwin D, Stuckey E. Reliability of a Clinical Test to Detect scapular dyskinesia. The Journal of Orthopaedic and Sports Physical Therapy. 2007; 37(1): A24. PRESENTATIONS Kareha S. Musculoskeletal Imaging of the Cervical Spine, Grand Rounds, St. Luke’s University Health Network, Tilghman Street Clinic; Feb 2014; Allentown, PA. Kareha S. Mobilizations. Grand Rounds, WellSpan Deatrick Commons Clinic; July 2012; Gettsyburg, PA. Kareha S. Residency Education. Grand Rounds presented to WellSpan Health staff – York County; Jan 2011; York, PA. Kareha S. Lumbar Spine Evaluation. Grand Rounds, WellSpan Adams Health Center; Nov 2011; Gettysburg, PA.

RESEARCH.SLUHN.ORG | 105

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION 106

Podiatry & Foot Care St. Luke’s University Health Network has long been recognized for its excellence in the area of podiatry and foot care. In fact, St. Luke’s offers the only podiatric residency program in the Lehigh Valley area. Its faculty includes national pioneers in the area of podiatric dermatology. Under the leadership of Robert A. Diamond, DPM, Chief, Division of Podiatry and Director of the Podiatry Surgery Residency; William De Long, MD, FACS, Chief, Department of Orthopaedic Surgery and Brent H. Bernstein, DPM, Director of Research Division of Podiatry, St. Luke’s podiatric physicians and residents are actively involved in research and scholarly activities. These include participating in national clinical trials, partaking in surgical mission trips to Ecuador, presenting original contributions at major national meetings and publishing articles in major peer-reviewed scientific journals.

St. Luke’s state-of-the-art Podiatry Center treats a broad range of podiatric problems, from claw foot to plantar fasciitis and nerve dysfunction. In addition to serving the patients of the busy clinical practice, the faculty and residents are actively involved in a number of high-profile research projects and clinical trials.

The three-year Podiatric Residency Program helps train experts in podiatric medicine and surgery. The program started in 1991 with a single residency slot. Due to growth in foot surgery volume throughout the St. Luke’s University Health Network, the program now accepts nine residents in each class. The program also offers one elective fourth-year position as a Podiatric Dermatology Fellowship — one of the first nationally recognized fellowships in podiatry by the Council on Podiatric Medical Education.

Clinic Hours Mon-Thu: 8 am – 8 pm Fri: 8 am – 5 pm

Contact Information Podiatry Center 1501 Lehigh Street Allentown, PA 18104 610-628-8260

Podiatric Residency: 610-628-8364 Questions about Outpatient Clinical Trials: Contact appropriate principal investigator directly.

St. Luke’s podiatric physicians and residents are actively involved in research and scholarly activities.

PUBLICATIONS Bernstein B, Bailey J, Statkewicz M. Improving Split Thickness Graft Take with Negative Pressure Wound Therapy With Open Cell Foam in High Risk Patients. Submitted to Journal of Foot and Ankle Surgery. Bernstein B, Lam H, Motko J. Update on Developing a Comprehensive Diagnostic and Treatment Plan for Charcot Neuroarthropathy – Part I and II. Podiatry Management. January/February 2013. Bernstein B, Ritter Z, Diamond R. Neuropathic Ankle Arthrodesis with Intramedullary Nail Fixation. The Foot and Ankle Online Journal. July 2012; 5(7). Bernstein B, Williams A, Pinegar D, Stolzfus J, Vella J. Bone Markers in Charcot Neuroarthropathy. Submitted to Diabetologia. Bernstein B. VAC Therapy with Split Thickness Skin Grafts. Present eLearning, Best Practice in Woundcare. Nov 2013; 1(1). Creech CL, Malan JR, Meyr AJ. Evaluation of the Sagittal Saw Blade as an Intraoperative Fomite During Diabetic Foot Surgery. Foot & Ankle Specialist. Nov 2014. Pii:1938640014560162. Epub ahead of print. Gabriel A, Shores J, Bernstein B, de Leon J, Kamepalli R, Wolvos T, Baharestani M, Gupta S. A Clinical Review of Infected Wound Treatment with Vacuum Assisted Closure “V.A.C.” Therapy: Experience and Case Studies. International Wound Journal Supplement. Oct 2009; 6(Suppl 2): 1-25. doi: 10.1111/j.1742-481X.2009.00628.x. Stannard J, Atkins Z, O’Malley D, Singh H, Bernstein B, Fahey M, Masden D, Attinger C, MD. Use of Negative Pressure Therapy on Closed Surgical Incisions: A Case Series. Journal Ostomy and Wound Management. Aug 2009; 55(8): 58-66.

RESEARCH.SLUHN.ORG | 107

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION 108

ABSTRACTS

PRESENTATIONS

Bernstein B, Hawley S. Reverse Sural Artery Pedicle Flap Technique for Heel Ulcer Coverage: A Case Review. Poster. ACFAS Annual Scientific Conference; Feb 2013; Las Vegas, NV.

Bernstein B. Advisory Panel Presentation on Epidermal Skin Grafting. SAWC; Oct 2014; Las Vegas, NV.

Bernstein B, Joseph E. Class V Sanders Charcot Deformity Revisional Repair of a Complex Calcaneal Fracture: A Case Review. Poster. ACFAS Annual Scientific Conference; Feb 2013; Las Vegas, NV. Bernstein B, Seiler D. Inferior Calcaneal Slide Osteotomy for the Treatment of a Sagittal Plane Dominant Charcot Foot Deformity. Poster. ACFAS Annual Scientific Conference; Feb 2014; Orlando, FL. Bernstein B. Engenex速 Negative-Pressure Wound Therapy System and Its Success in the Treatment of a Diabetic Foot Wound: A Case Study. Poster. Diabetic Limb Salvage Conference; Oct 2010; Washington, D.C.

Bernstein B. Epidermal Skin Grafting. Invited Lecturer. Steelfoot 2 Conference; Oct 2014; Bethlehem, PA. Bernstein B. Plastic Surgery in Podiatric Medicine. Invited Lecturer. Oklahoma State Podiatric Medical Association Annual Conference; Oct 2012; Oklahoma City, OK. Bernstein B. Sural Artery Flaps. Invited Lecturer. Steelfoot Conference; Oct 2013; Bethlehem, PA. Bernstein B. The Science of Wound Healing and Apligraf. Invited Lecturer. Community Lecture; March 2014; Sellerville, PA.

RESEARCH.SLUHN.ORG | 109

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Radiology St. Luke’s University Health Network is committed to providing physicians with leading edge imaging technology to give them a clearer picture of their patients’ health conditions. Hal L. Folander, MD, Network Chairman of the Radiology Department, leads a team of nearly 40 radiologists who specialize in areas such as interventional and neurointerventional radiology, advanced breast imaging, neuroradiology, nuclear medicine, musculoskeletal ultrasound, CT and MRI. With more than 25 network locations, these physicians read exams from all six St. Luke’s hospitals, numerous outpatient centers and many physician offices. St. Luke’s radiologists are skilled in using some of the most advanced technology available. For example, St. Luke’s University Hospital – Bethlehem is home to the Discovery IGS 730 Hybrid OR from GE Healthcare. The first hospital in the United States to offer this technology, the interventional suite brings a radiology lab into the operating room. St. Luke’s University Health Network has been designated an international show site for GE Medical Systems. Physicians, clinical staff and administrators from all over the world visit St. Luke’s facilities to observe procedures being performed using this advanced equipment. Additionally, St. Luke’s radiologists and staff train other physicians, staff and GE applications specialists in its use. Designated a Center of Excellence by the American College of Radiology, St. Luke’s Regional Breast Center was the first facility of its kind in the region to exclusively provide a higher-level of breast imaging. Advanced imaging technology offered at the Center includes automated breast ultrasound (ABUS), which provides a clearer, more accurate evaluation of dense breast tissue and elastography, which measures the tissue density of a mass using ultrasound. Advanced imaging technology is available at other sites, including the St. Luke’s Women’s Imaging Center in the West End Medical Center, Allentown, the location of the new low dose 3D mammography system – GE’s SenoClaire® breast tomosynthesis and also the new SensorySuite®.

110

Using a low-dose, short X-ray sweep around the compressed breast, the 3D technology separates the tissues to reduce overlapping of structures, a limiting factor in standard 2D mammography. The SensorySuite® uses the senses of sight, sound and smell simultaneously to create a pleasant atmosphere to reduce a woman’s worry or anxiety. St. Luke’s University Health Network radiologists participate in many research activities which include, but are not limited to: National Institute of Health sponsored ATTRACT trial for lower extremity deep vein thrombosis, The Angel® Catheter Clinical Trial: Prevention of Pulmonary Embolism in High Risk Subjects as well as multiple trials in the realm of interventional oncology. Additionally, the Network offers breast screening, diagnostic and treatment services throughout the Lehigh Valley, Bucks County, Monroe County and Warren County in New Jersey. PUBLICATIONS Bell D, Kozakewich HP, Fishman SJ, Kulungowski AM, Alomari AI. Liver Hemgiomas and Elevated Serum Alpha-Fetoprotein: Unresolved Questions. Human Pathology. 2011; 42(9)1369 Chen S, Harisinghani M, Wittenberg J. Small Bowel CT Fat Density Target Sign in Chronic Radiation Enteritis. Australasian Radiology. 2003; 47(4): 450. doi: 10.1016/j. humpath.2011.05.013.

Physicians, clinical staff, and administrators from all over the world visit St. Luke’s facilities to observe procedures being performed using this advanced equipment.

Chen S, Oâ&#x20AC;&#x2122;Neill MJ, Gervais D. Management of Tubo-ovarian Abscess. Semin Interventional Radiology. 2003; 20 (03). Fras IM, Wong TZ. PET/CT Protocols and Practical Issues for the Evaluation of Patients with Head and Neck Cancer. PET Clinics. Oct 2008; 2(4). Harisinhani M, Wittenberg J, Lee W, Chen S, Gutierrez Al, Mueller PR. Bowel Wall Fat Halo Sign in Patients without Intestinal Disease. American Journal of Roentgenology. 2003; 181(3): 781. Horrow MM, Stassi J, Shurman AM, Brody JD, Kirb CL, Rosenberg HK. The Limitations of Carotid Sonography: Interpretive and Technology Related Errors. AJR. 2000; 174(5): 189. James IAO, Moukhalled A, Yu E, Tulman DB, Bergese SD, Jones CD, Stawicki SP, Evans DC. A Systematic Review of the Need for MRI for the Clearance of Cervical Spine Injury in Obtunded Blunt Trauma Patients after Normal Cervical Spine CT. Journal of Emergencies, Trauma and Shock. 2014; 7(4): 251. Khatri VP, Stuppino JJ, Espinosa MH, Pollack MS. Improved Accuracy in Differentiating Malignant from Benign Mammographic Abnormalities: A Simple, Improved Magnetic Resonance Imaging Method. Cancer. 2001; 92: 471. Lorenz JM, Thomas JL. Complications of Percutaneous Fluid Drainage. Seminars in Interventional Radiology. 2006; 23(2): 194. Yoo AJ, Schaefer PW, Bell D, Barak ER, Romero JM, Nogueira RG, Lev MH, Schwamm LH, Gonzalez RG, Hirsch JA. CT Angiography-Source Image Hypoattenuation Predicts Clinical Outcome in Posterior Circulation Strokes Treated with Intra-Arterial Therapy Stroke 2008: 39.

RESEARCH.SLUHN.ORG | 111

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Surgery St. Luke’s University Health Network has significantly expanded its faculty and therefore the breadth of clinical expertise in recent years. Led by Dr. Marc Granson, surgeons from respected institutions throughout the country have been recruited to St. Luke’s University Health Network. Equipped with leading edge technology, St. Luke’s surgeons continuously bring advanced procedures to residents of the Lehigh Valley and surrounding areas. For example, St. Luke’s University Hospital – Bethlehem is home to the Discovery IGS 730 Hybrid OR from GE Healthcare. The first hospital in the United States to offer this technology, the interventional suite essentially brings a radiology laboratory into the operating room. An international show site for GE Medical Systems, physicians from all over the world visit St. Luke’s to observe procedures being performed there. The state-of-the-art facilities’ advanced procedures include transcatheter aortic valve replacements (TAVR). In 2014, cardiac surgeons and interventional cardiologists at St. Luke’s University Hospital – Bethlehem were the first in the region, and among the first group of hospitals in the country, to implant a smaller and more refined second-generation transcatheter aortic valve. Under the direction of Dr. Marc Granson, Chairman of Surgery, surgeons perform a broad variety of laparoscopic, robotic-assisted, endoscopic and single-incision procedures. An early adopter and innovator, St. Luke’s University Hospital was one of the first hospitals in North America to introduce robotic surgery. In 2012, St. Luke’s Allentown Campus and gynecologic surgeons Michael Patriarco, DO, St. Luke’s Director of Minimally Invasive GYN Surgery; Tirun Gopal, MD; Sheldon Linn, MD and David Hanes, MD were awarded the Center of Excellence designation in Minimally Invasive Gynecology™ (COEMIG).

112

SURGICAL EDUCATION Surgical education is a priority for St. Luke’s University Health Network, which offers residencies in general surgery and orthopaedic surgery. The general surgery residency provides access to a large number of diverse cases. The bulk of residents’ time is spent in the operating room. Under the watchful eye of experienced faculty members, surgical residents are encouraged to make patient care decisions. Many of the general surgery residents go on to prestigious fellowships. Fourth year general surgery residents may opt to complete a rotation through the International Surgical Studies Program — a partnership between St. Luke’s University Hospital’s Division of Trauma and Acute Care Surgery (ACS) and the Mbingo Baptist Hospital in Cameroon, Africa. The St. Luke’s University Health Network Orthopaedic Surgery Residency is a rigorous, five-year training program that prepares residents to be leaders in the orthopaedic community. Upon completion of this program, residents will have the knowledge and skills necessary to compete for the best fellowships available in their area of interest. The St. Luke’s Trauma Fellowship offers both a twoyear Surgical Critical Care Fellowship for emergency medicine graduates and a one-year fellowship for graduates of general surgery programs. In 2012, the Fellowship was awarded ACGME (Accreditation Council for Graduate Medical Education) accreditation, and was approved by the American Board of Surgery to include surgical critical care into the curriculum and training. St. Luke’s is one of the first institutions to offer a two-year track for a surgical critical care fellowship for emergency medicine residency graduates approved by the American Board of Surgery.

An early adopter and innovator, St. Luke’s University Hospital was one of the first hospitals in North America to introduce robotic surgery.

ST. LUKE’S UNIVERSITY HOSPITAL ADULT LEVEL I TRAUMA CENTER Celebrating its 15th anniversary, the St. Luke’s University Hospital Adult Level I Trauma Center has done much more than provide state-of-the-art care of the injured from all corners of Lehigh Valley, eastern Pennsylvania and western New Jersey. Our Level I Trauma Center is among the top 5 percent of trauma centers in Pennsylvania and has undergone two consecutive accreditation cycles with no citations. Under the leadership of William S. Hoff, MD, FACS, Chief, Division of Trauma & Acute Care Surgery; Peter Thomas, DO, FACOG, Trauma Program Medical Director; James Cipolla, MD, FACS, Section Head, Surgical Critical Care and Marc Portner, MD, Associate Director of Surgical Critical Care Fellowship, the program has trained experts in trauma and surgical critical care for nearly a decade. This, combined with the establishment of the Medical School of Temple University/St. Luke’s University Health Network, has positioned the Center as a leader in trauma medical education. In addition, the Division of Trauma & Acute Care Surgery is among the research leaders of the St. Luke’s University Health Network, with clinical research being at the forefront of its mission. Physicians and staff are actively involved in research and scholarly activities. They participate in high-profile national clinical trials, present original contributions at major national meetings and publish work in notable, peer-reviewed scientific journals. More recently, the Division of Trauma & Acute Care Surgery has seen tremendous growth in volume and acuity of general surgery cases performed by its surgeons. This mission complements greatly the efforts of Brian A. Hoey, MD, FACS, Director, General Surgery Residency, by fostering a synergistic relationship between clinical practice, medical education and research.

RESEARCH.SLUHN.ORG | 113

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

THORACIC SURGERY

PUBLICATIONS

The Division of Thoracic Surgery is staffed by two board-certified cardiothoracic surgeons, Drs. William Burfeind and Matthew Puc, who focus solely on general thoracic surgery. Their practice is heavily weighted toward thoracic cancers such as lung, esophagus, thymus and chest wall. A multidisciplinary team evaluates all patients. Performing more than 550 thoracic surgical procedures per year, the surgeons submit all their operative data to the Society of Thoracic Surgeons General Thoracic Surgery Database and have their outcomes benchmarked to the most prestigious centers in the United States. The practice is committed to continually developing expertise in minimally invasive surgery and performs more than 96 percent of their early-stage lung cancer operations thoracoscopically. The Lung Cancer Multidisciplinary Team ensures that all patients eligible for a clinical trial are offered enrollment.

Burfeind WR Jr. Invited commentary. Annals of Thoracic Surgery. Feb. 2014; 97(2): 431. doi: 10.1016/j. athoracsur.2013.11.005.

Centers of Excellence: • Optum (United Health Care) Bariatric Centers of Excellence Network • Aetna Institute of Quality in Bariatric Surgery • Cigna 3 Star Quality Bariatric Surgery Center • Blue Distinction + Center for Bariatric Surgery • MBSAQIP (Metabolic and Bariatric Surgery Accreditation Quality Improvement Program) Accredited Center – Comprehensive. APPOINTMENTS William R. Burfeind Jr., MD • Associate Clinical Professor of Surgery, Temple School of Medicine. • Society of Thoracic Surgery Taskforce memberships (General Thoracic Surgery Database, Access and Publication, Quality Initiatives, Public Reporting). Matthew M. Puc, MD • Assistant Clinical Professor of Surgery, Temple School of Medicine.

114

Crabtree TD, Kosinski AS, Puri V, Burfeind W, Bharat A, Patterson GA, Hofstetter W, Meyers BF. Evaluation of the Reliability of Clinical Staging of T2 N0 Esophageal Cancer: A Review of the Society of Thoracic Surgeons Database. Annals of Thoracic Surgery. 2013 Aug; 96(2): 382-90. doi: 10.1016/j.athoracsur.2013.03.093. El Chaar M, Claros L, Ezeji G, Miletics M, Stoltzfus J. Improving Outcomes of Bariatric Surgery: Best Practices in an Accredited Surgical Center. Obesity Surgery. 2014; 24(7): 1057-1063. doi: 10.1007/s11695014-1209-y. Habeeb K, Jeanmonod R. Extensive Retroperitoneal Air, Pneumomediastinum and Subcutaneous Air Secondary to Stercoral Perforation. The American Journal of Emergency Medicine. Feb 2014; 32(2):193. e3-4. doi: 10.1016/j.ajem.2013.09.002 Hall BT, Englehart MS, Blaseg K, Wessel K, Stawicki SP, Evans DC. Implementation of a Dietitian-led Enteral Nutrition Support Clinic Results in Quality Improvement, Reduced Readmissions, and Cost Savings. Nutrition in Clinical Practice. 2014; 29(5): 649-655. Martinez JC, Thomas JL, Lukaszczyk JJ. Single Incision Laparoscopic Surgery Approach for Obscure Small Intestine Bleeding Localized by CT Guided Percutaneous Injection of Methylene Blue. International Journal of Surgical Case Reports. 2014; 5(12): 1082-1085. doi: 10.1016/j.ijscr.2014.06.020. St Julien JB, Aldrich MC, Sheng S, Deppen SA, Burfeind WR Jr, Putnam JB, Lambright ES, Nesbitt JC, Grogan EL. Obesity Increases Operating Room Time for Lobectomy in the Society of Thoracic Surgeons Database. Annals of Thoracic Surgery. Dec 2012; 94(6): 1841-1847. doi: 10.1016/j.athoracsur.2012.08.006. Tong BC, Kosinski AS, Burfeind WR Jr, Onaitis MW, Berry MF, Harpole DH Jr, D’Amico TA. Sex Differences in Early Outcomes After Lung Cancer Resection: Analysis of the Society of Thoracic Surgeons General Thoracic Database. Journal of Thoracic Cardiovascular Surgery. 2014 Jul;148(1):13-8. doi: 10.1016/j. jtcvs.2014.03.012.

ABSTRACTS El Chavar M, Claros L, Miletics M, Stoltzfus J. Single Center Experience in “Fast-Track” Bariatric Surgery: A Feasibility Study. Surgery for Obesity and Related Diseases. 2011; 7(3): 394. doi:10.1016/j.soard.2011.04.065. PRESENTATIONS Claros L, El Chaar M, Miletics M. Outcomes of Usage of Two Different Buttressing Materials in Bariatric Surgery: A Single Center Experience. ASMBS Conference; Nov 2013; Atlanta, GA. El Chaar M, Claros L, Miletics M. Safety of Bariatric Surgery in the Elderly Patient. ASMBS Conference; Nov 2013; Atlanta, GA. El Chaar M, Claros L, Miletics M. Pattern of Weight Loss in Different Categories of Obesity Following Laparoscopic Sleeve Gastrectomy: A Single Center Experience. ASMBS Conference; Nov 2013; Atlanta, GA. El Chaar M, Claros L, Miletics M. Super Obese vs. Morbidly Obese Patients: Clinical Outcomes and Estimated Weight Loss. ASMBS Conference; Nov 2013; Atlanta, GA. El Chaar M, Claros L, Miletics M, Stoltzfus J. Laparoscopic Vertical Sleeve Gastrectomy vs Laparoscopic Roux-en-y-gastric Bypass: Single Center Experience with 1 Year Follow-up. ASMBS Conference; June 2012; San Diego, CA. El Chaar M, Claros L, Miletics M, Stoltzfus J. Safety of Laparoscopic Bariatric Surgery in the Superobese Patients: Single Center Experience. ASMBS Conference; June 2012; San Diego, CA. Miletics M, et. al. Is Age of Obesity Onset a Determinant in Weight Loss After Bariatric Surgery. ASMBS Conference; Nov 2013; Atlanta, GA.

RESEARCH.SLUHN.ORG | 115

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Traumatology, Surgical Critical Care & Acute Care Surgery The St. Luke’s University Network Trauma Program is committed to providing exceptional patient care, offering outstanding education, conducting research and sharing its experience with colleagues throughout the country. The St. Luke’s Division of Trauma & Acute Care Surgery has trained experts in critical care for nearly a decade. It is led by William S. Hoff, MD, FACS, Division Chief; Peter Thomas, DO, FACOG, Trauma Program Medical Director; James Cipolla, MD, FACS, Section Head, Surgical Critical Care and Director of the Surgical Critical Care Fellowship; and Marc Portner, MD, Associate Director of Surgical Critical Care Fellowship. This effort, combined with the establishment of the Medical School of Temple University/St. Luke’s University Health Network, established St. Luke’s Level I Trauma Center as a local leader in trauma and medical education. In addition, the Division of Trauma & Acute Care Surgery is among the research leaders of the St. Luke’s University Health Network, with clinical research being at the forefront of its mission. Trauma physicians and staff are actively involved in research and scholarly activities, participating in high-profile national clinical trials, presenting original contributions at regional and national meetings and publishing in major scientific journals. More recently, the Division of Trauma & Acute Care Surgery has seen tremendous growth in the volume and acuity of general surgery cases performed by its surgeons. This clinical mission greatly complements the efforts of Brian A. Hoey, MD, FACS, Director, General Surgery Residency, by fostering a synergistic relationship between clinical practice, medical education and research.

PUBLICATIONS Avery DM, Carolan, GF. Traumatic Obturator Hip Dislocation in a 9-year-old Boy. The American Journal of Orthopaedics. Sept 2013; 42(9): E81-83. Bahner DP, Evans DC, Lindsey DE, Stawicki SP. What’s New in Critical Illness and Injury Science? The Challenge of Verifying Tracheal Airway Placement: Solving the Puzzle One Piece at a Time. International Journal of Critical Illness and Injury Science. April 2013; 3: 105-107. doi: 10.4103/2229-5151.114266. Dalal PP, Otey AJ, McGonagle EA, Whitmill ML, Levine EJ, McKimmie RL, Thomas AC, Cook CH, Papadimos TJ, Reilley TE, Bergese SD, Steinberg SM, Stawicki SP, Evans DC. Intentional Foreign Object Ingestions: Need for Endoscopy and Surgery. Journal of Surgical Research. Sept 2013; 184(1): 145-149. doi: 10.1016/j. jss.2013.04.078. Doshi NM, Cook CH, Mount KL, Stawicki SP, Frazee EN, Personett HA, Schramm GE, Arnold HM, Murphy CV. Adjunctive Aerosolized Colistin for Multi-drug Resistant Gram-negative Pneumonia in the Critically Ill: A Retrospective Study. BioMed Central Anesthesiology. Nov 2013; 13(1): 45. doi: 10.1186/1471-2253-13-45. doi: 10.1186/1471-2253-13-45. Eiferman DS, Davido HT, Howard JM, Gerckens J, Evans DC, Cook CH, Stawicki SP. Two Methods of Hemodynamic and Volume Assessment in Critically Ill Patients: A Study of Disagreement. Journal of Intensive Care Medicine. April 2014. [Epub ahead of print]. Evans DC, Khoo KM, Radulescu A, Cook CH, Gerlach AT, Papadimos TJ, Steinberg SM, Stawicki SP, Eiferman DS. Pre-injury Beta Blocker Use Does Not Affect the Hyperdynamic Response in Older Trauma Patients. Journal of Emergencies, Trauma and Shock. Oct 2014; 7(4): 305-309. doi: 10.4103/0974-2700.142766.

116

Located at St. Luke’s University Hospital – Bethlehem, the Trauma Center has completed two consecutive accreditation cycles with no citations.

Evans DC, Wojda TR, Jones C, Otey AJ, Stawicki SP. Intentional Ingestions of Foreign Objects Among Prisoners: A Review. World Journal of Gastrointestinal Endoscopy. 2015; 7(3): 162-168. doi: 10.4253/wjge.v7.i3.162. Gerlach AT, Folino J, Morris BN, Murphy CV, Stawicki SP, Cook CH. Comparison of Heparin Dosing Based on Actual Body Weight in Non-obese, Obese and Morbidly Obese Critically Ill Patients. International Journal of Critical Illness and Injury Science. 2013; 3(3): 195-199. doi: 10.4103/2229-5151.119200. Hall BT, Englehart MS, Blaseg K, Wessel K, Stawicki SP, Evans DC. Implementation of a Dietitian-led Enteral Nutrition Support Clinic Results in Quality Improvement, Reduced Readmissions, and Cost Savings. Nutrition in Clinical Practice. 2014; 29(5): 649-655. Hoff J, Grell J, Lohrman N, Stehly C, Stoltzfus J, Wainwright G, Hoff WS. Distracted Driving and Implication for Injury Prevention in Adults. Journal of Trauma Nursing. 2013; 20(1): 31-34. doi: 10.1097/JTN.0b013e318286616c. Kent A, Bahner DP, Boulger CT, Eiferman DS, Adkins EJ, Evans DC, Springer AN, Balakrishnan JM, Valiyaveedan S, Galwankar S, Njoku C, Lindsey DE, Yeager S, Roelant GJ, Stawicki SP. Sonographic Evaluation of Intravascular Volume Status in the Surgical Intensive Care Unit: A Prospective Comparison of Subclavian Vein and Inferior Vena Cava Collapsibility Index. Journal of Surgical Research. Sept 2013; 184(1): 561-566. doi: 10.1016/j. jss.2013.05.040. Kalra S, Kelkar D, Galwankar SC, Papadimos TJ, Stawicki SP, Arquilla B, Hoey BA, Sharpe RP, Sabol D, Jahre JA. The Emergence of Ebola as a Global Health Security Threat: From ‘Lessons Learned’ to Coordinated Multilateral Containment Efforts. Journal of Global Infectious Diseases. Oct 2014; 6(4): 164-177. doi: 10.4103/0974-777X.145247.

RESEARCH.SLUHN.ORG | 117

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Kwiatt M, Tarbox A, Seamon MJ, Swaroop M, Cipolla J, Hallenbeck S, Davido HT, Lindsey DE, Doraiswamy VA, Galwankar SC, Tulman D, Latchana N, Papadimos TJ, Cook CH, Stawicki SP. Thoracostomy tubes: A Comprehensive Review of Complications and Related Topics. International Journal of Critical Illness and Injury Science. April 2014; 4(2):143-155. Leskovan JJ, Justiniano CF, Bach JA, Cook CH, Lindsey DE, Eiferman DS, Papadimos TJ, Steinberg SM, Bergese SD, Stawicki SP, Evans DC. Anion Gap as a Predictor of Trauma Outcomes in the Older Trauma Population: Correlations with Injury Severity and Mortality. The American Surgeon. Nov 2013; 79(11): 1203-1206. doi: 10.4103/2229-5151.134182. Mansfield SA, Stawicki SP, Forbes RC, Papadimos TJ, Lindsey DE. Acute Upper Gastrointestinal Bleeding Secondary to Kaposi Sarcoma as Initial Presentation of HIV Infection. Journal of Gastrointestinal and Liver Diseases. Dec 2013; 22(4): 441-445. Marchigiani R, Gordy S, Cipolla J, Adams RC, Evans DC, Stehly C, Galwankar S, Russell S, Marco AP, Kman N, Bhoi S, Stawicki SP, Papadimos TJ. Wind Disasters: A Comprehensive Review of Current Management Strategies. International Journal of Critical Illness and Injury Science. April 2013; 3(2):130-142. doi: 10.4103/2229-5151.114273. Martinez JC, Thomas JL, Lukaszczyk JJ. Single Incision Laparoscopic Surgery Approach for Obscure Small Intestine Bleeding Localized by CT Guided Percutaneous Injection of Methylene Blue. International Journal of Surgery Case Reports. 2014; 5(12): 1082-1085. doi: 10.1016/j.ijscr.2014.06.020. Moffatt-Bruce SD, Cook CH, Steinberg SM, Stawicki SP. Risk Factors for Retained Surgical Items: A Meta-analysis and Proposed Risk Stratification System. Journal of Surgical Research. 2014; 190(2): 429-436. doi: 10.1016/j. jss.2014.05.044. Morrison J, Jeanmonod R. Imaging of the NEXUSnegative Patient: When We Break the Rule. American Journal of Emergency Medicine. 2014; 32(1): 67-70. doi: 10.1016/j.ajem.2013.08.062.

118

Otey AJ, Houser JS, Jones C, Evans DC, Dalal P, Whitmill ML, Levine E, McKimmie R, Papadimos TJ, Steinberg SM, Bergese SD, Stawicki SP. Examination of Financial Charges Associated with Intentional Foreign Body Ingestion by Prisoners: A Pattern of Escalation. OPUS 12 Scientist. 2014; 8(1): 6-8. Pal R, Agarwal A, Galwankar S, Swaroop M, Stawicki SP, Rajaram L, Paladino L, Aggarwal P, Bhoi S, Dwivedi S, Menon G, Misra M, Kalra O, Singh A, Radjou AN, Joshi A. The 2014 Academic College of Emergency Experts in India’s INDO-US Joint Working Group (JWG) White Paper on “Developing Trauma Services in India.” International Journal of Critical Illness and Injury Science. 2014; 4(2): 114-130. doi: 10.4103/2229-5151.134151. Papadimos TJ, Gafford EF, Stawicki SP, Murray MJ. Diagnosing Dying. Anesthesia and Analgesia. 2014; 118(4): 879-882. doi: 10.1213/ANE.0000000000000043. Pappada SM, Cameron BD, Tulman DB, Bourey RE, Borst MJ, Olorunto W, Bergese SD, Evans DC, Stawicki SP, Papadimos TJ. Evaluation of a Model for Glycemic Prediction in Critically Ill Surgical Patients. Public Library of Science One. July 2013; 8(7): e69475. doi: 10.1371/journal.pone.0069475. Patil P, Kelly N, Papadimos TJ, Bahner DP, Stawicki SP. Correlations Between Venous Collapsibility and Common Hemodynamic and Ventilatory Parameters: A Multi-variable Assessment. OPUS 12 Scientist. 2014; 8(1): 1-5. Prabhakaran S, Doraiswamy VA, Nagaraja V, Cipolla J, Ofurum U, Evans DC, Lindsey DE, Seamon MJ, Kavuturu S, Gerlach AT, Jaik NP, Eiferman DS, Papadimos TJ, Adolph MD, Cook CH, Stawicki SP. Nasoenteric Tube Complications. Scandinavian Journal of Surgery. 2012; 101(3): 147-155. doi: 10.1177/145749691210100302. Saliba L, Stawicki SP, Thongrong C, Bergese SD, Papadimos TJ, Gerlach AT. Association Between In-hospital Acute Hypertensive Episodes and Outcomes in Older Trauma Patients. Internal & Emergency Medicine. 2014; 9(5): 553-8. doi: 10. 1007/s11739-013-0984-0.

Stawicki SP, Adkins EJ, Eiferman DS, Evans DC, Ali NA, Njoku C, Lindsey DE, Cook CH, Balakrishnan JM, Valiaveedan S, Galwankar SC, Boulger CT, Springer AN, Bahner DP. Prospective Evaluation of Intravascular Volume Status in Critically Ill Patients: Does Inferior Vena Cava Collapsibility Correlate with Venous Pressure? The Journal of Trauma and Acute Care Surgery. 2014; 76(4): 956-964. doi: 10.1097/TA.0000000000000152. Stawicki SP, Bahner DP. Modern Sonology and the Bedside Practitioner: Evolution of Ultrasound from Curious Novelty to Essential Clinical Tool. European Journal of Trauma & Emergency Surgery. Nov 2014. [Epub ahead of print]. doi: 10.1007/s00068-014-0464-x. Stawicki SP, Cook CH, Anderson HL 3rd, Chowayou L, Cipolla J, Ahmed HM, Coyle SM, Gracias VH, Evans DC, Marchigiani R, Adams RC, Seamon MJ, Martin ND, Steinberg SM, Moffatt-Bruce SD; OPUS 12 Foundation Multicenter Trials Group. Natural History of Retained Surgical Items Supports the Need for Team Training, Early Recognition, and Prompt Retrieval. American Journal of Surgery. July 2014; 208(1): 65-72. doi: 10.1016/j. amjsurg.2013.09.029. Stawicki SP, Green JM, Martin ND, Green RH, Cipolla J, Seamon MJ, Eiferman DS, Evans DC, Hazelton JP, Cook CH, Steinberg SM. Results of a Prospective, Randomized, Controlled Study of the Use of Carboxymethylcellulose Sodium Hyaluronate Adhesion Barrier in Trauma Open Abdomens. Surgery. 2014; 156(2): 419-430. doi: 10.1016/j. surg.2014.03.007. Stawicki SP, Stoltzfus JC, Aggarwal P, Bhoi S, Bhatt S, Kalra OP, Bhalla A, Hoey BA, Galwankar SC, Paladino L, Papadimos TJ. Academic College of Emergency Experts in Indiaâ&#x20AC;&#x2122;s INDO-US Joint Working Group and OPUS12 Foundation Consensus Statement on Creating A Coordinated, Multi-Disciplinary, Patient-Centered, Global Point-of-Care Biomarker Discovery Network. International Journal of Critical Illness & Injury Science. 2014; 4(3): 200-208. doi: 10.4103/2229-5151.141398.

RESEARCH.SLUHN.ORG | 119

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Thongrong C, Kasemsiri P, Hofmann JP, Bergese SD, Papadimos TJ, Gracias VH, Adolph MD, Stawicki SP. Amniotic Fluid Embolism. International Journal of Critical Illness and Injury Science. 2013; 3(1): 51-57. doi: 10.4103/2229-5151.109422.

Wilson LN, Wainwright GA, Stehly CD, Stoltzfus J, Hoff WS. Assessing the Academic and Professional Needs of Trauma Nurse Practitioners and Physician Assistants. Journal of Trauma Nursing. 2013; 20(1): 51-55. doi: 10.1097/JTN.0b013e31828661e9.

Tripathi RS, Russell SB, Lyaker MR, Stawicki SP, Papadimos TJ. An Iatrogenic Metabolic Encephalopathy in a Nonagenarian: The Dilemma of a Critical Miss as a Possible Social Dismissal. International Journal of Critical Illness and Injury Science. 2013; 3(4): 282-283. doi: 10.4103/2229-5151.124169.

Wisler JR, Springer AN, Hateley K, Mo XM, Evans DC, Cook CH, Gerlach AT, Murphy CV, Eiferman DS, Steinberg SM, Bergese SD, Papadimos TJ, Stawicki SP. Pre-injury Neuro-psychiatric Medication Use, Alone or in Combination with Cardiac Medications, May Affect Outcomes in Trauma Patients. Journal of Postgraduate Medicine. 2014; 60(4): 366-371. doi: 10.4103/00223859.143957.

Tsavoussis A, Stawicki SP, Stoicea N, Papadimos TJ. Child-witnessed Domestic Violence and its Adverse Effects on Brain Development: A Call for Societal Self-examination and Awareness. Front Public Health. 2014; 2:178. doi: 10.3389/fpubh.2014.00178. eCollection 2014.

120

ABSTRACTS Stawicki SP, Green JM, Martin ND, Green RH, Cipolla J, Seamon MJ, Eiferman DS, Evans DC, Hazelton JP, Cook CH, Steinberg SM. Results of a Prospective, Randomized, Controlled Study of the Use of Carboxymethylcellulose Sodium Hyaluronate Adhesion Barrier in Trauma Open Abdomens. Journal of Surgical Research. 2014; 156(2): 585. doi: 10.1016/j. surg.2014.03.007. Moffatt-Bruce SD, Stawicki SP. System-wide Implementation of the Safe Surgical Checklist: Productive Not Disruptive. Journal of Surgical Research. 2014; 186(2): 675. Moffatt-Bruce SD, Cook CH, Steinberg SM, Stawicki SP. Risk Factors for Retained Surgical Items: A Meta-analysis and Proposed Risk Stratification System. Journal of Surgical Research. 2014; 186(2): 531. doi: 10.1016/j.jss.2014.05.044. Jones C, Boulger CT, Adkins EJ, Evans DC, Bahner DP, Stawicki SP. A Prospective Study of Pulmonary Artery Pressures and Inferior Vena Cava Collapsibility in Surgical ICU Patients. Journal of Surgical Research. 2014; 186(2): 510-511. Jones C, McGonagle EA, Stawicki SP, Evans DC. Intentional Ingestion of Foreign Bodies and Psychiatric Disease Among Prisoners. Journal of Surgical Research. 2014; 186(2): 687. Gerlach A, Blais D, Jones GM, Burcham P, Stawicki S, Cook C, Murphy C. High Dose Dexmedetomidine is Not Associated with Increased Risk of Hypotension. Pharmacotherapy. 2013; 33(10): E194. Forbes R, Jones C, Njoku C, Tulman D, Evans DC, Bergese S, Thongrong C, Kong N, Stawicki SP. Continuous Versus Bolus Tube Feeds: Does the Modality Affect Glycemic Variability or Insulin Requirements? Journal of the American College of Surgeons. 2013; 217(3): S57-S58. doi: 10.1016/j.jamcollsurg.2013.07.119. Stawicki SP, Anderson III HL, Coyle SM, Ahmed HM, Chowayou, Marchigiani R, Cipolla J, Gracias VH, Moffatt-Bruce SD, Seamon MJ, Adams RC, Steinberg SM, Stehly C, Cook CH. Natural History of Retained Surgical Items: Results of a Multi-Center Study. Journal of Surgical Research. 2013; 179(2): 289. DOI: 10.1016/j.jss.2012.10.568 PRESENTATIONS Kropf J, Grossman M; Salen P, Genzlinger M, Stehly C, Stoltzfus J, Carmona A. Ketamine vs. Etomidate for RSI in Traumatically Injured Patients: An Exploratory Study. American College of Emergency Physicians Scientific Assembly; Sept 2012; Denver, CO. Nwachuku, C. Philadelphia Orthopaedic Trauma Symposium: Surgical Techniques for Posterior Malleolus and Plafond Fixation; June 2013; Philadelphia, PA.

RESEARCH.SLUHN.ORG | 121

2015 ANNUAL REPORT

SLUHN DEPARTMENT OF RESEARCH & INNOVATION

Wound Care Center and Hyperbaric Medicine St. Luke’s University Health Network provides advanced diagnostics and treatment of non-healing wounds and ulcers. Specialty centers are located in Allentown, Bethlehem, Coaldale and Quakertown, PA and Phillipsburg, NJ. The multidisciplinary team of professionals includes general surgeons, trauma surgeons, plastic and vascular surgeons, podiatrists, infectious disease physicians, specially trained wound care nurses, certified wound ostomy continence nurses (CWOCN) and certified wound specialists (CWS). Under the direction of Dr. John Lukaszczyk, Network Medical Director of Wound Care, the staff of the five St. Luke’s Wound Management Centers facilitates more than 14,000 patient visits per year, not including hyperbaric oxygen treatments. Available at four of the five locations, hyperbaric oxygen (HBO) therapy, treats conditions including non-healing, complicated diabetic ulcers, lower extremity limb salvage, nonhealing wounds due to radiation complications (STRN), radiation induced cystitis, proctitis and enteritis and dental/jaw complications associated with a history of radiation to the neck and jaw and chronic bone infections. St. Luke’s Wound Management Centers treat the entire spectrum of non-healing wounds and cutaneous manifestations of co-morbidities such as scleroderma, pyoderma gangrenosum and systemic lupus erythematosus (SLE). Dr. Lukaszczyk also serves as the Chief of Minimally Invasive Surgery, Section Chief of General Surgery and Associate Program Director for the General Surgery Residency Program. He also is a Clinical Associate Professor of Surgery, Temple University School of Medicine and is a surgery faculty member of the University of Pennsylvania School of Medicine. Among his many accomplishments, Dr. Lukaszczyk was the first surgeon in Pennsylvania to perform robotic surgery using the daVinci Surgical System.

122

Because a nuanced understanding of the issues affecting a person’s ability to heal is so crucial to treating the wound itself, the doctors and nurses of the St. Luke’s Wound Management Centers coordinate with referring physicians and facilitate other clinical and non-clinical services to provide comprehensive patient care. PUBLICATIONS Cipolla J, Baillie DR, Steinberg SM, Martin ND, Jaik NP, Lukaszczyk JJ, Stawicki SP. Negative Pressure Wound Therapy: Unusual and Innovative Applications. OPUS 12 Scientist. 2008; 2(3): 15-29. Novetsky AP, Zighelboim I, Guntupalli SR, Ioffe YJ, Kizer NT, Hagemann AR, Powell MA, Thaker PH, Mutch DG, Massad LS. A Phase II Trial of a Surgical Protocol to Decrease the Incidence of Wound Complications in Obese Gynecologic Oncology Patients. Gynecological Oncology. 2014; 134(2): 233-237. doi: 10.1016/j. ygyno.2014.06.012.

St. Luke’s Wound Management Centers treat the entire spectrum of non-healing wounds and cutaneous manifestations of co-morbidities.

RESEARCH.SLUHN.ORG | 123

R E S E A R C H . I N N O VA T I O N . K N O W L E D G E .

801 OSTRUM STREET • BETHLEHEM, PA 18015

LEARN MORE ABOUT ST. LUKE’S RESEARCH & INNOVATION AT

RESEARCH.SLUHN.ORG