Microbiome Care vs Skin Care .....

Mirobiome care vs Skin care…………

By DrK Dermal Health Science

DrK Dermal Health Care is a boutique style Microbiome care, Skin care brand, which applies a minimalistic product prescription approach toward optimum skin health by following a formulary of less molecules, less microbiome interference, less inflammation. The DrK cellREVERSE range is a range that pioneers the science behind optimum skin health by utilising the Skin-Brain- Gut Axis to improve external physical perception of the skin.

What sets this DrK Dermal Health Care brand apart is that after many years of research we perfected the science behind offering the skin organ the correct building blocks it needs to take up natural skin functions within the skin that were deactivate by an urbanised lifestyle. When these building blocks are utilised optimally the organ will start to naturally repair, protect, and heal itself, as it was initially created to do.

All the products in the DR K Dermal Health Care cellREVERSE range are intended to reinforce the skin's microbial and physical barrier function, helping achieve a reinforced skin, especially for people living in urban environments and harsh climates.

Master Opinion Leader, Founder and Formulator

Dr. Juanita Kilian, qualified as a pharmacist at the University of North West, South Africa, in which thereafter she earned her Master's degree in Dermaceutical product development and her Doctorate in Transdermal Delivery Technology at the University of London, School of Pharmacy. Dr.Juanita Kilian has engaged in the study of transdermal delivery systems and has made unique formulation discoveries, which has a profound influence on the development of the Dr K Dermal Health Care product range. She is also a researcher and author of some of the most acknowledged and influential educational material used and applied in more than 25 countries. Throughout her career, Dr. Juanita Kilian has worked extensively in South Africa, Africa, United Kingdom, Scandinavia, UAE, Russia, and various parts of Europe in which during this time she has been actively researching and re-educating herself with the latest skin technology and dermaceutical chemistry information available, leaving her with a passionate interest in the development of effective therapeutic skincare applications. Today, based in Pretoria, South Africa, she is the director of CosmoPharm Product Design (Pty)Ltd a leading dermaceutical consulting company and the founder and developer of the Dr K Dermal Health Care brand with the extensive focus on skin health and healing.

Science….be mindful of its being applied.

The Dr K Dermal Health Care is a dermatological pre and pro biotic skin renewal system that was scientifically designed to down regulate inflammatory disorders in the skin and improve skin health on all aspects from the basal layers to the skin microbiota.

Science and the Anatomy of the skin as a vital organ is our passion and therefore this brand successfully treats skin disorders like ageing, hyperpigmentation, acne, eczema, and chronic redness. With research,

the focus always remains on the development of innovative pre and probiotic skin renewal systems. This range of dermaceutical applications focusses on activation of natural physiological skin functionals, rather than supplementation of high concentrations of heavy loaded active molecules. DrK cellREVERSE is unique as all formulations contains a patented Nucleotide Complex for optimum cellular health…

Putting you completely in the picture about the science behind nucleotides

Nucleotides are often referred to as “the building blocks of life” because they are the most basic structural components of our DNA.

Our body gets nucleotides from:

• Recycled nucleotides from worn out or dying cells - salvage pathway.

• Newly produced nucleotides within the cell synthesised from amino acids or glucose.

• The food we eat - our diet.

• A nutritional supplement.

All these sources have limitations:

• The recycling of nucleotides from dying cells is only 60% effective and time and energy consuming.

• Additionally, some of the most important systems cannot produce their own nucleotides such as some brain cells, cells coming from the bone marrow like immune cells and red blood cells and some cells of the skin and gut flora. Other cells, like cells of the intestinal wall (villi), can produce nucleotides but not enough to cover their entire need.

• The availability of nucleotides from food is low. Additionally, nucleotides are found in higher concentrations only in meat and mostly in organ meat (such as liver, kidney, etc.) that we no longer consume. Fruits and vegetables are very low in nucleotides. This results in the need to supplement nucleotides.

• Our intake of naturally occurring nucleotides is generally low. The typical modern, fast paced lives we live, constant high levels of stress and restricted dietary intake have resulted in nucleotide supplementation becoming a lifestyle induced essentiality.

Nucleotide Restrictions in our Modern Day

Dietary simplification is a term used to describe the reduction in nucleotide content of the modern diet. It is also important to remember that a varied diet will ensure that the full spectrum of all 5 nucleotides is ingested. So even though we think our diet is varied - we may not have the full spectrum of nucleotides available to supply our bodies' needs

We are overfed but under nourished! Why are nucleotides so important?

Nucleotides are not only the “building blocks of life”, but they are also involved in almost all the activities of each cell. Nucleotides are essential for cell regeneration, transfer of energy, production of protein and the mediation of hormone signals.

Most cells in the body can utilise nucleotides from the

synthesis and salvage pathway but other cells need a continuous supply of nucleotides from the diet. There are cells that rely on the dietary sources of nucleotides, and they are: •Cells forming the lining of the digestive tract (intestinal mucosa cells). The good bacteria in the intestinal tract - Bifidobacteria.

• White blood cells of the immune system and red blood cells (specifically erythrocytes). •Dermal/Epidermal cells

These 5 cell types have a rapid turnover in the body as they are the most important cells that ensure our health and the optimal biological processes of our digestive and immune systems. Our bodies can cope with changes and challenges (like disease and stress) and react optimally only when nucleotides are easily available and in sufficient quantities. Only a continuous balanced supply of nucleotides can ensure that these tissues and cells can function optimally. This can be guaranteed by an adequate supplementation of the correct portion of nucleotides.

Nucleotides and its relevance in DrK ceLLREVERSE: Cell Regeneration

Our bodies are in a continued state of flux in which tissues have a varied cell turnover rate. As cells age, they become damaged through everyday wear and tear and therefore need to be renewed. The cells that are used more frequently have a higher replacement rate i.e. the cells that form the intestinal villi are replaced every 3-5 days, cells that line the stomach last only 5 days, skin cells regenerates approximately every 27 days and red blood cells last only 120 days.

Cell regeneration requires an exact copy of the genetic information stored in the DNA needs to be made. It is essential to our well-being that this replication is done without errors as these may result in a loss of immunity, disease, or even genetic mutations. To ensure accurate replication each cell must have access to a pool of freely available, relevant nucleotide bases to build the copy from and supply of RNA and various enzymes to stimulate and provide the energy (ATP/GTP) for these reactions.

The double helix unzips at critical points to allow uncoiling and exposing of the DNA sequence that needs to be duplicated. The two complimentary halves are exposed so that the freely available nucleotides can be matched up in their relevant pairs. Because these nucleotides can only line up in complimentary fashion it ensures that the two emerging strands of DNA are identical to the original template. Only now can the process of cell division begin to take place. It should be clear that without a balanced pool of nucleotides available and ready-for-use, cellular replication could be delayed or put on hold indefinitely until the required nucleotide is produced or made available for use in a specific position.

DrK cellREVERSE applications all contains a unique Nucleotide Complex that makes a pool of Nucleotides in the correct ratio available for dermal and epidermal cells to speed up the cell replication process but also ensuring that good quality new cells are formed.