LIVErNEWS Issue 78, Spring 2022

The PANORAMIC Clinical Study The PANORAMIC clinical study is currently looking for participants with COVID-19, including people with chronic liver disease.

What is the PANORAMIC clinical study?

The information below is taken from the study website and explains more about the research: 'PANORAMIC is a UK-wide clinical study sponsored by the University of Oxford and funded by the National Institute for Health Research.'

'The purpose of this clinical study is to nd new treatments that help those suffering with COVID-19 at home and in the community get better quicker and without needing to be treated in hospital. Most people with COVID-19 are treated in the community and so we need to nd treatments that are suitable and effective for use early on in the illness.

PANORAMIC aims to nd out if new antiviral medicines help to keep people with COVID19 from needing to be admitted to hospital and help people to get better. All of the treatments in the PANORAMIC trial have been approved by the UK Medicines and Health Care Products Regulatory Agency (MHRA) for use in the study (which regulates the use of all medicines in the UK), and the study is approved by the Health Research Authority.'

'We are recruiting volunteers, whether they have been vaccinated or not, to join PANORAMIC through this website (www.panoramictrial.org), participating GP practices, and other NHS sites across the UK. PANORAMIC is open to everyone with ongoing symptoms of COVID-19 and a positive PCR or Lateral Flow test, regardless of vaccination status.

You can participate in your own home from anywhere in the UK for the rst treatment being tested in PANORAMIC. No face-to-face visits are required.'

'Those consenting to be part of the study will be randomly selected to either be in a group who receives a course of an antiviral treatment, or a group that doesn't. Two different groups are needed so the study team can see any difference in the health of those who received the antiviral treatment compared to those who didn't.'

'Follow up will be by answering questions each day online and/or telephone calls with the study team, who will be there to support you throughout the study.'

Who can participate in the PANORAMIC clinical study?

Below are further details from the study website about who can participate in the research.

You are eligible to join PANORAMIC if: You are currently experiencing COVID-19 symptoms beginning in the last 5 days.

AND: You have had a positive PCR or Lateral Flow test for COVID-19 LIVErNEWS No. 78 ~ 17 ~ Spring 2022