The PRINCIPLE Trial & PANORAMIC Study update - Sian O’Dea

The PRINCIPLE trial is currently looking for participants with COVID-19.

What is the PRINCIPLE Trial?

The information below is taken from the study website and explains more about the research:

'PRINCIPLE is a UK-wide clinical study from the University of Oxford to nd COVID-19 treatments for recovery at home. We are looking for medicines that can help people with COVID-19 symptoms get better quickly and stop them needing to go to hospital. PRINCIPLE is recruiting participants through this website (www.principletrial.org) and also through GP practices across the UK. PRINCIPLE is open to all with ongoing symptoms of COVID-19, regardless of vaccination status.'

Who can participate in the PRINCIPLE Trial?

Below are further details from the study website about who can participate in the research. You are eligible to join PRINCIPLE if:

‘You are currently experiencing COVID-19 symptoms for 14 days or less. AND: You have had a positive test for COVID-19 in the last 14 days AND: You are aged 18 or over’

So far, over 10,000 people have volunteered to participate.

Where can you nd out further information about the study?

The PRINCIPLE Trial has its own website: www.principletrial.org. This has additional information about the study, including a Participant Information Leaet.

Contact details for the study are:

Email: principle@phc.ox.ac.uk Telephone: 0800 138 0880 There is a link on the website where you can click to join the PRINCIPLE Trial if you wish. Alternatively, you can ring the telephone number above. Your GP may also be able to help you to enrol for the study.

Update on the PANORAMIC Clinical Study:

Over 25,000 people have now participated in the PANORAMIC Clinical Study which was outlined in the last edition of LIVErNEWS. You can no longer join this trial online. There are however still some GP practices who can enrol people for the trial. The results of this study are awaited.