SUMMARY In 2015 a total of 127,000 transplantations were performed worldwide, an increase of 5.8% from 2014, with 33,000 of these occurring in the EU and 32,000 in the US. Approximately 60% of these were kidney transplants, with liver, heart, lung, pancreas and small bowel transplantations accounting for the other most common procedures. When a graft is transplanted from a genetically non-identical individual, the recipient’s immune system recognizes the graft as foreign.
SCOPE There are 63 distinct first-in-class molecular targets in development for transplantation. Which of these hold the strongest potential in the clinic, and which are closest to reaching the market? How effective are current therapies for these indications, and how have they been able to improve the general prognosis in recent decades?
Which molecule types and molecular targets are most prominent across transplantation therapy? Which specific types of transplantation are being most heavily studied across the pharmaceutical pipeline?
REASONS TO BUY Appreciate the current clinical and commercial landscapes Identify leading products and key unmet needs within the market.
Recognize trends in pipeline innovation by analyzing therapies by stage of development Assess the therapeutic potential of first-in-class targets
Consider first-in-class pipeline products with no prior involvement in licensing
TABLE OF CONTENTS Executive Summary The Case for Innovation Clinical and Commercial Landscape Assessment of Pipeline Product Innovation Others
RELATED REPORTS Frontier Pharma: Transplantation Therapeutics - A Highly Innovative Pipeline with a Range of Adaptive and Innate Immune-Targeting Programs Focusing on GraftVersus-Host Disease and Kidney Transplantation POC/Point-of-Care Infectious Disease Testing Market Forecast 2017-2021: New Frontiers, Business Challenges, Emerging Technologies, Competitive Landscape Frontier Pharma: Neurodegenerative Diseases - Protein Misfolding Targets and Neuromodulators Dominate the First-in-Class Pipeline and Lead the Way as Potential Disease-Modifying Therapies in AD and PD Frontier Pharma: Renal Diseases - High Degree of Innovation and Diversity with Products Targeting Immune and Hormone Signaling Dominating the Pipeline for Chronic Kidney Disease
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