Antifungals market to 2017 generic erosion of major polyenes, azoles

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Antifungals Market to 2017 - Generic Erosion of Major Polyenes, Azoles, Allylamines and Echinocandins to Slow Value Growth Released On 27th June 2014 GBI Research, the leading business intelligence provider has released its latest research Antifungals Market to 2017 - Generic Erosion of Major Polyenes, Azoles, Allylamines and Echinocandins to Slow Value Growth, which provides an insight into antifungals sales and price forecasts until 2017. The report examines the global antifungal therapies, treatment usage patterns and treatment flow algorithm. In addition, the geographical distribution of antifungal therapies across the US, the top five countries in the European region and Japan are also provided in the report. The report also includes insights into the Research and Development (R&D) pipeline and the potential future blockbusters until 2017 with in-depth analysis of the top three antifungal therapeutic indications, namely aspergillosis, dermatophytosis and candidiasis. Furthermore, it also includes the market forecasts and treatment usage patterns of these three therapeutic indications. The report also explores the competitive landscape including top companies benchmarking. Finally, the key trend analysis on Mergers and Acquisitions (M&A) and licensing agreements involving antifungals therapies is also presented.

In-depth analysis of the report is based on propriety databases, primary and secondary research and in-house analysis by the GBI Research team of experts. Buy this report OR Know more : http://www.jsbmarketresearch.com/healthcaremedical/r-Antifungals-Market-to-2017-Generic-Erosion-of-Major-Polyenes-Azoles41090 GBI Research analysis shows that the global antifungals market was estimated at $9.4 billion in 2010, with a Compound Annual Growth Rate (CAGR) of 2.9% during 2002 and 2010. The antifungals market is dominated by generics. GBI Research forecasts that the market will grow at a CAGR of 1.9% during 2010-2017 to $10.8 billion. The patent expiry of a number of major drugs has paved way for the entry of generics. GBI Research analysis shows that the R&D pipeline for the antifungals market is not strong as it JSB Market Research Pvt. Ltd.

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has become a generic market. Currently, only 38 molecules are in R&D, which indicates that antifungals R&D activity will not be very active for at least the next seven to eight years. Scope - Data and analysis on the antifungals market in the leading geographies of the world the US, the UK, Germany, France, Italy, Spain, and Japan. - Annualized market data for the antifungals market from 2002-2010 with forecasts to 2017. - Market data on the geographical landscape and therapeutic landscape, including market size, market share, annual cost of therapy, sales volume and treatment usage patterns such as disease population, treatment seeking population, diagnosis population and prescription population. - The competitive landscape of the global antifungals market including top companies benchmarking. - Key M&A activities and licensing agreements that took place in 2009, 2010 and 2011 in the antifungals market. Reasons to buy - Build effective strategies to launch their pipeline products by identifying potential geographies. - Exploit in-licensing and out-licensing opportunities by identifying products that might fill their portfolio gaps. - Develop key strategic initiatives by studying the key strategies of top competitors. - Develop market entry and market expansion strategies by identifying the geographic markets poised for strong growth. - Reinforce R&D pipelines by identifying new target mechanisms which can produce safer and more efficacious first-in-class molecules. Table of Content: 1.1 List of Tables 6 1.2 List of Figures 8 2 Global Antifungals Market to 2017 - Introduction 10 2.1 Overview 10 2.2 GBI Research Report Guidance 11 3 Global Antifungals Market to 2017 - Market Characterization 12 3.1 Introduction 12 3.2 Different Classes of Antifungals 12 3.3 Forecast for Global Antifungals Market 14 3.3.1 Revenues 14 3.3.2 Branded and Generic Market Share 15 3.3.3 Annual Cost of Treatment (ACT) 16 3.3.4 Treatment Usage Patterns 17 3.4 Drivers for the Antifungals Market 23 JSB Market Research Pvt. Ltd.

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3.4.1 Large Patient Population 23 3.4.2 Increase in Diagnosis Rate 23 3.5 Barriers for the Antifungals Market 23 3.5.1 Prominence of Generics in the Market 23 3.5.2 High Unmet Need in Case of Serious Invasive Fungal Infections 23 4 Global Antifungals Market - Geographical Landscape 24 4.1 Revenue Analysis by Geography 24 4.2 The US 24 4.2.1 Revenue 24 4.2.2 Annual Cost of Treatment 26 4.2.3 Treatment Usage Pattern 27 4.3 Top Five Countries of Europe 33 4.3.1 Revenue 33 4.3.2 Annual Cost of Treatment 35 4.3.3 Treatment Usage Pattern 36 4.4 Japan 42 4.4.1 Revenue 42 4.4.2 Annual Cost of Treatment 43 4.4.3 Treatment Usage Pattern 44 5 Global Antifungals Market - Aspergillosis Therapeutics Market 50 5.1 Introduction 50 5.2 Market Forecasts 50 5.3 Annual Cost of Treatment 52 5.4 Treatment Usage Patterns 55 5.4.1 Diseased Population 57 5.4.2 Treatment Seeking Population 58 5.4.3 Diagnosed Population 59 5.4.4 Prescription Population 60 5.5 Treatment Flow Algorithm 61 5.5.1 Allergic Bronchopulmonary Aspergillosis 61 5.5.2 Invasive Aspergillosis 62 5.6 Branded and Generic Market Share 63 5.7 Major Marketed Products 64 5.7.1 Voriconazole (vfend) 64 5.7.2 Amphotericin B (amphocin) 64 5.7.3 AmBisome (amphotericin B) liposome for injection 64 5.7.4 Itraconazole (sporanox) 65 5.7.5 Caspofungin (cancidas) 65 5.7.6 Posaconazole (noxafil) 65 6 Global Antifungals Market - Dermatophytosis Therapeutics Market 66 6.1 Introduction 66 JSB Market Research Pvt. Ltd.

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6.2 Market Forecasts 66 6.3 Annual Cost of Treatment 68 6.3.1 Annual Cost of Treatment for Tinea Cruris 68 6.3.2 Annual Cost of Treatment for Tinea Unguium (Onychomycosis) 70 6.3.3 Annual Cost of Treatment for Tinea Pedis 72 6.3.4 Annual Cost of Treatment for Tinea Capitis 74 6.3.5 Annual Cost of Treatment for Tinea Corporis 76 6.4 Treatment Usage Patterns 78 6.4.1 Diseased Population 80 6.4.2 Treatment Seeking Population 81 6.4.3 Diagnosed Population 82 6.4.4 Prescription Population 83 6.5 Treatment Flow Algorithm for Dermatophytosis 84 6.6 Branded and Generic Market Share 85 6.7 Major Marketed Products 86 6.7.1 Ketoconazole 2% cream (nizoral) 86 6.7.2 Clotrimazole 1% cream or lotion (lotrimin) 86 6.7.3 Econazole 1% cream or lotion (spectazole) 86 6.7.4 Miconazole 2% cream (monistat) 86 6.7.5 Terbinafine (lamisil) 87 6.7.6 Naftifine 1% cream (naftifin) 87 6.7.7 Griseofulvin 87 6.7.8 traconazole (sporanox) 87 6.7.9 Fluconazole (diflucan) 88 6.7.10 Sertaconazole nitrate cream (ertaczo) 88 7 Global Antifungals Market - Candidiasis Therapeutics Market 89 7.1 Introduction 89 7.2 Market Forecasts 89 7.3 Annual Cost of Treatment 91 7.3.1 Annual Cost of Treatment for Vaginal Candidiasis 91 7.3.2 Annual Cost of Treatment for Cutaneous Candidiasis 93 7.3.3 Annual Cost of Treatment for Oropharyngeal Candidiasis 94 7.3.4 Annual Cost of Treatment for Esophageal Candidiasis 95 7.3.5 Annual Cost of Treatment for Invasive Candidiasis 96 7.4 Treatment Usage Patterns 97 7.4.1 Diseased Population 99 7.4.2 Treatment Seeking Population 100 7.4.3 Diagnosed Population 101 7.4.4 Prescription Population 102 7.5 Treatment Flow Algorithm for Candidiasis 103 7.6 Branded and Generic Market Share 104 JSB Market Research Pvt. Ltd.

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7.7 Major Marketed Products 105 7.7.1 Fluconazole 105 7.7.2 Itraconazole Oral Solution 105 7.7.3 Clotrimazole 105 7.7.4 Canestan 105 7.7.5 Anidulafungin (eraxis) 106 7.7.6 Nystatin Oral Suspension 106 7.7.7 Daktarin IV Solution 106 8 Global Antifungals Market - Pipeline Analysis 107 8.1 Introduction 107 8.2 Aspergillosis: Research and Development Pipeline 108 8.2.1 Overview 108 8.2.2 Phase lll 108 8.2.3 Phase ll 108 8.2.4 Phase l 108 8.2.5 Preclinical 108 8.2.6 Discovery 109 8.3 Dermatophytosis: Research and Development Pipeline 109 8.3.1 Overview 109 8.3.2 Phase lll 109 8.3.3 Phase ll 109 8.3.4 Phase l 110 8.3.5 Preclinical 110 8.4 Candidiasis: Research and Development Pipeline 110 8.4.1 Overview 110 8.4.2 Phase lll 110 8.4.3 Phase ll 110 8.4.4 Phase l 111 8.4.5 Preclinical 111 8.5 Profiles of Promising Drugs in the Antifungals Market 111 8.5.1 Eraxis + Vfend 111 8.5.2 Isavuconazole 112 8.5.3 NAFT-500 112 8.5.4 Fluconazole 113 9 Global Antifungals Market - Competitive Landscape 114 9.1 Company Profiles 114 9.1.1 Ferrer Internacional S.A. 114 9.1.2 BioDelivery Sciences International, Inc. 115 9.1.3 Pfizer Inc. 116 9.1.4 Merck & Co Inc 117 9.1.5 Astellas Pharma Inc 118 JSB Market Research Pvt. Ltd.

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10 Global Antifungals Market - Strategic Consolidations 120 10.1 Mergers and Acquisitions 120 10.1.1 Overview 120 10.1.2 Major Mergers and Acquisitions Deals 120 10.1.3 M&A by Year 120 10.1.4 M&A by Deal Value 121 10.1.5 M&A by Geography 121 10.2 Co-Development Deals 122 10.2.1 Overview 122 10.2.2 Major Co-Development Deals 122 10.3 Licensing Deals 122 10.3.1 Overview 122 10.3.2 Major Licensing Deals 122 10.3.3 Licensing Deals by Year 123 11 Global Antifungals Market - Appendix 126 11.1 Market Definitions 126 11.2 Abbreviations 126 11.3 Research Methodology 127 11.3.1 Coverage 127 11.3.2 Secondary Research 128 11.3.3 Primary Research 128 11.4 Therapeutic Landscape 129 11.4.2 Market Size by Geography 131 11.5 Geographical Landscape 131 11.6 Pipeline Analysis 132 11.7 Competitive Landscape 132 11.7.1 Expert Panel Validation 132 11.8 Contact Us 132 11.9 Disclaimer 132 11.10 Sources 133 List of Tables Table 1: Antifungals Market to 2017, Different Classes of Antifungals, 2011 12 Table 2: Antifungals Market to 2017, Global, Revenues ($bn), 2002-2010 14 Table 3: Antifungals Market to 2017, Global, Revenues ($bn), 2010-2017 14 Table 4: Antifungals Market to 2017, Global, Annual Cost of Treatment ($), 2002-2010 16 Table 5: Antifungals Market to 2017, Global, Annual Cost of Treatment ($), 2010-2017 16 Table 6: Antifungals Market to 2017, Global, Treatment Usage Patterns, (million), 2002-2010 17 Table 7: Antifungals Market to 2017, Global, Treatment Usage Patterns, (million), 2010-2017 18 Table 8: Antifungals Market to 2017, The US, Revenues ($bn), 2002-2010 25 JSB Market Research Pvt. Ltd.

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Table 9: Antifungals Market to 2017, The US, Revenues ($bn), 2010-2017 25 Table 10: Antifungals Market to 2017, The US, Annual Cost of Treatment ($), 2002-2010 26 Table 11: Antifungals Market to 2017, The US, Annual Cost of Treatment ($), 2010-2017 26 Table 12: Antifungals Market to 2017, The US, Treatment Usage Patterns (million), 2002-2010 27 Table 13: Antifungals Market to 2017, The US, Treatment Usage Patterns (million), 2010-2017 28 Table 14: Antifungals Market to 2017, Top Five Countries of Europe, Revenues ($m), 2002-2010 33 Table 15: Antifungals Market to 2017, Top Five Countries of Europe, Revenues ($m), 2010-2017 34 Table 16: Antifungals Market to 2017, Top Five Countries of Europe, Annual Cost of Treatment ($), 2002-2017 35 Table 17: Antifungals Market to 2017, Top Five Countries of Europe, Annual Cost of Treatment ($), 2002-2017 35 Table 18: Antifungals Market to 2017, Top Five Countries of Europe, Treatment Usage Patterns (million), 2002-2010 36 Table 19: Antifungals Market to 2017, Top Five Countries of Europe, Treatment Usage Patterns (million), 2010-2017 37 Table 20: Antifungals Market to 2017, Japan, Revenues ($m), 2002-2010 42 Table 21: Antifungals Market to 2017, Japan, Revenues ($m), 2010-2017 42 Table 22: Antifungals Market to 2017, Japan, Annual Cost of Treatment ($), 2002-2010 43 Table 23: Antifungals Market to 2017, Japan, Annual Cost of Treatment ($), 2010-2017 43 Table 24: Antifungals Market to 2017, Japan, Treatment Usage Patterns, (million), 2002-2010 44 Table 25: Antifungals Market to 2017, Japan, Treatment Usage Patterns, (million), 2010-2017 45 Table 26: Aspergillosis Therapeutics Market, Global, Revenues ($m), 2002-2010 50 Table 27: Aspergillosis Therapeutics Market, Global, Revenues ($m), 2010 2017 50 Table 28: Aspergillosis Therapeutics Market, Global, Annual Cost of Treatment, Allergic Bronchopulmonary Aspergillosis ($), 2002-2010 52 Table 29: Aspergillosis Therapeutics Market, Global, Annual Cost of Treatment, Allergic Bronchopulmonary Aspergillosis ($), 2010-2017 52 Table 30: Aspergillosis Therapeutics Market, Global, Annual Cost of Treatment, Invasive Aspergillosis ($), 2002-2010 53 Table 31: Aspergillosis Therapeutics Market, Global, Annual Cost of Treatment, Invasive Aspergillosis ($), 2010-2017 53 Table 32: Aspergillosis Therapeutics Market, Global, Factors Influencing Life Threatening Infection, Invasive Aspergillosis, 2011 54 Table 33: Aspergillosis Therapeutics Market, Global, Treatment Usage Pattern (million), 20022010 55 Table 34: Aspergillosis Therapeutics Market, Global, Treatment Usage Pattern (million), 20102017 56 JSB Market Research Pvt. Ltd.

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Table 35: Dermatophytosis Therapeutics Market, Global, Revenues ($bn), 2002-2010 66 Table 36: Dermatophytosis Therapeutics Market, Global, Revenues ($bn), 2010-2017 67 Table 37: Dermatophytosis Therapeutics Market, Global, Annual Cost of Treatment, Tinea Cruris ($), 2002-2010 68 Table 38: Dermatophytosis Therapeutics Market, Global, Annual Cost of Treatment, Tinea Cruris ($), 2010-2017 68 Table 39: Dermatophytosis Therapeutics Market, Global, Annual Cost of Treatment, Tinea Unguium ($), 2002-2010 70 Table 40: Dermatophytosis Therapeutics Market, Global, Annual Cost of Treatment, Tinea Unguium ($), 2010-2017 70 Table 41: Dermatophytosis Therapeutics Market, Global, Annual Cost of Treatment, Tinea Pedis ($), 2002-2010 72 Table 42: Dermatophytosis Therapeutics Market, Global, Annual Cost of Treatment, Tinea Pedis ($), 2010-2017 72 Table 43: Dermatophytosis Therapeutics Market, Global, Annual Cost of Treatment, Tinea Capitis ($), 2002-2010 74 Table 44: Dermatophytosis Therapeutics Market, Global, Annual Cost of Treatment, Tinea Capitis ($), 2010-2017 74 Table 45: Dermatophytosis Therapeutics Market, Global, Annual Cost of Treatment, Tinea Corporis ($), 2002-2010 76 Table 46: Dermatophytosis Therapeutics Market, Global, Annual Cost of Treatment, Tinea Corporis ($), 2010-2017 76 Table 47: Dermatophytosis Therapeutics Market, Global, Treatment Usage Patterns, (million), 2002-2010 78 Table 48: Dermatophytosis Therapeutics Market, Global, Treatment Usage Patterns, (million), 2010-2017 79 Table 49: Candidiasis Therapeutics Market, Global, Revenues ($bn), 2002-2010 89 Table 50: Candidiasis Therapeutics Market, Global, Revenues ($bn), 2010-2017 90 Table 51: Candidiasis Therapeutics Market, Global, Annual Cost of Treatment, Vaginal Candidiasis ($), 2002-2010 91 Table 52: Candidiasis Therapeutics Market, Global, Annual Cost of Treatment, Vaginal Candidiasis ($), 2010-2017 91 Table 53: Candidiasis Therapeutics Market, Global, Annual Cost of Treatment, Cutaneous Candidiasis ($), 2002-2010 93 Table 54: Candidiasis Therapeutics Market, Global, Annual Cost of Treatment, Cutaneous Candidiasis ($), 2010-2017 93 Table 55: Candidiasis Therapeutics Market, Global, Annual Cost of Treatment, Oropharyngeal Candidiasis ($), 2002-2010 94 Table 56: Candidiasis Therapeutics Market, Global, Annual Cost of Treatment, Oropharyngeal Candidiasis ($), 2010-2017 94 Table 57: Candidiasis Therapeutics Market, Global, Annual Cost of Treatment, Esophageal JSB Market Research Pvt. Ltd.

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Candidiasis ($), 2002-2010 95 Table 58: Candidiasis Therapeutics Market, Global, Annual Cost of Treatment, Esophageal Candidiasis ($), 2010-2017 95 Table 59: Candidiasis Therapeutics Market, Global, Annual Cost of Treatment, Invasive Candidiasis ($), 2002-2010 96 Table 60: Candidiasis Therapeutics Market, Global, Annual Cost of Treatment, Invasive Candidiasis ($), 2010-2017 96 Table 61: Candidiasis Therapeutics Market, Global, Treatment Usage Patterns (million), 20022010 97 Table 62: Candidiasis Therapeutics Market, Global, Treatment Usage Patterns (million), 20102017 98 Table 63: Aspergillosis Therapeutics Market, Global, Phase lll, 2011 108 Table 64: Aspergillosis Therapeutics Market, Global, Phase ll, 2011 108 Table 65: Aspergillosis Therapeutics Market, Global, Phase l, 2011 108 Table 66: Aspergillosis Therapeutics Market, Global, Preclinical, 2011 108 Table 67: Aspergillosis Therapeutics Market, Global, Discovery, 2011 109 Table 68: Dermatophytosis Therapeutics Market, Global, Phase lll, 2011 109 Table 69: Dermatophytosis Therapeutics Market, Global, Phase ll, 2011 109 Table 70: Dermatophytosis Therapeutics Market, Global, Phase l, 2011 110 Table 71: Dermatophytosis Therapeutics Market, Global, Preclinical, 2011 110 Table 72: Candidiasis Therapeutics Market, Global, Phase lll, 2011 110 Table 73: Candidiasis Therapeutics Market, Global, Phase ll, 2011 110 Table 74: Candidiasis Therapeutics Market, Global, Phase l, 2011 111 Table 75: Candidiasis Therapeutics Market, Global, Preclinical, 2011 111 List of Figures Figure 41: Dermatophytosis Therapeutics Market, Global, Revenues ($bn), 2002-2017 66 Figure 42: Dermatophytosis Therapeutics Market, Global, Annual Cost of Treatment, Tinea Cruris ($), 2002-2017 68 Figure 43: Dermatophytosis Therapeutics Market, Global, Annual Cost of Treatment, Tinea Unguium ($), 2002-2017 70 Figure 44: Dermatophytosis Therapeutics Market, Global, Annual Cost of Treatment, Tinea Pedis ($), 2002-2017 72 Figure 45: Dermatophytosis Therapeutics Market, Global, Annual Cost of Treatment, Tinea Capitis ($), 2002-2017 74 Figure 46: Dermatophytosis Therapeutics Market, Global, Annual Cost of Treatment, Tinea Corporis ($), 2002-2017 76 Figure 47: Dermatophytosis Therapeutics Market, Global, Treatment Usage Patterns, (million), 2002-2017 78 Figure 48: Dermatophytosis Therapeutics Market, Global, Diseased Population (million), 2002JSB Market Research Pvt. Ltd.

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2017 80 Figure 49: Dermatophytosis Therapeutics Market, Global, Treatment Seeking Population (million), 2002-2017 81 Figure 50: Dermatophytosis Therapeutics Market, Global, Diagnosed Population (million), 20022017 82 Figure 51: Dermatophytosis Therapeutics Market, Global, Prescription Population (million), 2002-2017 83 Figure 52: Dermatophytosis Therapeutics Market, Global, Treatment Flow Algorithm, 2011 84 Figure 53: Dermatophytosis Therapeutics Market, Global, Branded and Generic Market Share (%), 2010-2017 85 Figure 54: Candidiasis Therapeutics Market, Global, Revenues ($bn), 2002-2017 89 Figure 55: Candidiasis Therapeutics Market, Global, Annual Cost of Treatment, Vaginal Candidiasis ($), 2002-2017 91 Figure 56: Candidiasis Therapeutics Market, Global, Annual Cost of Treatment, Cutaneous Candidiasis ($), 2002-2017 93 Figure 57: Candidiasis Therapeutics Market, Global, Annual Cost of Treatment, Oropharyngeal Candidiasis ($), 2002-2017 94 Figure 58: Candidiasis Therapeutics Market, Global, Annual Cost of Treatment, Esophageal Candidiasis ($), 2002-2017 95 Figure 59: Candidiasis Therapeutics Market, Global, Annual Cost of Treatment, Invasive Candidiasis ($), 2002-2017 96 Figure 60: Candidiasis Therapeutics Market, Global, Treatment Usage Patterns (million), 20022017 97 Figure 61: Candidiasis Therapeutics Market, Global, Diseased Population (million), 2002-2017 99 Figure 62: Candidiasis Therapeutics Market, Global, Treatment Seeking Population (million), 2002-2017 100 Figure 63: Candidiasis Therapeutics Market, Global, Diagnosed Population (million), 2002-2017 101 Figure 64: Candidiasis Therapeutics Market, Global, Prescription Population (million), 20022017 102 Figure 65: Candidiasis Therapeutics Market, Global, Treatment Flow Algorithm, 2011 103 Figure 66: Candidiasis Therapeutics Market, Global, Branded and Generic Market Share (%), 2010-2017 104 Figure 67: Antifungals Market to 2017 to 2017, Global, Pipeline Analysis, 2011 107 Figure 68: Antifungals Market to 2017, SWOT Analysis - Ferrer Internacional SA 114 Figure 69: Antifungals Market to 2017, SWOT Analysis - BioDelivery Sciences International Inc 116 Figure 70: Antifungals Market to 2017, SWOT Analysis - Pfizer Inc 117 Figure 71: Antifungals Market to 2017, SWOT Analysis Merck & Co Inc 118 Figure 72: Antifungals Market to 2017, SWOT Analysis Astellas Pharma Inc 119 JSB Market Research Pvt. Ltd.

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Figure 73: Antifungals Therapeutics Market, Global, M&A by Year, 2009-2011 120 Figure 74: Antifungals Therapeutics Market, Global, M&A by Deal Value, 2009-2011 121 Figure 75: Antifungals Therapeutics Market, Global, M&A by Geography, 2009 -2011 121 Figure 76: Antifungals Therapeutics Market, Global, Licensing Deals by Year, 2009-2011 123 Figure 77: Antifungals Therapeutics Market, Global, Licensing Deals by Deal Value, 2009-2011 124 Figure 78: Antifungals Therapeutics Market, Global, Licensing Deals by Geography, 2009-2011 125 Related reports: •

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Figure 79: GBI Research Market Forecasting Model 131

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