PROGRAM AGENDA
Day 1 – Tuesday, May 16th, 2023
SRB Ted Couch Auditorium
4:00-5:00 PM
W. Jackson Pledger Researcher of the Year lecture: Anna Giuliano, Ph.D.
“Eliminating HPV-related Cancers – Research to Impact Public Health”
5:00-6:00 PM
Reception in SRB Murphy
Day 2 – Wednesday, May 17th, 2023
USF Marshall Student Center
8:00-9:00 AM
9:00-9:10 AM
9:10-9:35 AM
Registration, Breakfast & Poster Viewing in the Ballroom
Welcome, Ken Wright, PhD, ACD Research Education and Training (Oval Theater)
Featured Poster Presentations - Session I (Oval Theater)
Moderator: Dr. Katarzyna Rejniak
Dr. Luis Aguirre “Validation of the Molecular International Prognostic Scoring System (IPSS-M)
Risk Stratification Model for Myelodysplastic Syndromes”
Dr. Cherell Cottrell-Daniels “Associations of Cancer Treatment Status on Smoking Cessation
Among Survivors of CIN or Cervical Cancer”
Dr. Ou Deng “PARP16 modulates MYC expression and susceptibility of Ewing’s Sarcoma cells to PARP1 inhibition”
Dr. Ammoren Dohm “Upfront Osimertinib Alone Versus Osimertinib and Radiotherapy for the Treatment of EGFR-positive NSCLC Brain Metastases: A Multi-institutional Series”
Dr. Thomas Dombrowski “Tumor-immune ecosystem dynamics exploration via a high-resolution agent-based model”
Dr. Saurabh Garg “The correlation of oncodriver expression with tumor infiltrating lymphocytes in triple negative breast cancer (TNBC)”
Dr. Rebecca Hesterberg “Aging dampens lymphoma-provoked phenotypic and epigenomic changes to the adaptive immune system”
Dr. Filip Ionescu “Fludarabine Exposure Impact on Safety and Efficacy of Idecabtagene Vicleucel in Relapsed/Refractory Multiple Myeloma”
9:35-10:00 AM
Featured Poster Presentations - Session II (Oval Theater)
Moderator: Dr. Gage Redler
Dr. Daria Miroshnychenko “Stroma-induced cancer cell proliferation accelerates tumor recovery between chemotherapy cycles”
Mostafa Nasr “PRDM16: A key switch enabling long term skeletal dormancy and survival in prostate cancer”
Dr. Eleonora Pelle “A novel hormone-based anti-SSTR T-cell engager for the treatment of neuroendocrine tumors”
10:00-11:30 AM
11:30- 12:30 PM
12:00-1:30 PM
1:45-2:35 PM
Dr. Jennifer Perone “Evaluation of an Intraoperative Critical Event (ICE) Team at a Major Cancer Center”
Dr. Marilena Tauro “Novel autophagy inhibitory strategies to treat multiple myeloma”
Malgorzata Tyczynska-Weh “Modeling selection for evolvability in the evolution of cancer therapy resistance”
Dr. Tomas Zelenka “Bcl11b is a bimodal switch between stem-like and effector Trm cells in infection and tumor”
Poster Session #1 (Ballroom) Odd numbered Posters
Lunch (Ballroom)
Poster Session #2 (Ballroom) Even Numbered Posters
Oral Presentations – Session I (Oval Theater)
Moderator: Dr. Russell Palm
Dr. Facundo Davaro “Impact of Surgical Margin & Extent of Lymphadenectomy on Oncologic Outcomes in Plasmacytoid Urothelial Carcinoma”
Dr. Chandler Gatenbee “VALIS: Virtual Alignment of pathoLogy Image Series”
Vincent Law “Development of Intrathecal Drug Delivery Platform to Cure Breast Cancer
Leptomeningeal Disease by Dendritic Cell Immunotherapy in Preclinical Model”
Dr. Shelly Li “Effects of Social Isolation on Symptoms of Depression and Anxiety among Young Adult Cancer Survivors: The Mediating Role of Social Support”
Dr. Karnav Modi “Frailty and high-risk immuno-nutritional score are associated with inferior outcomes in patients with relapsed and refractory multiple myeloma treated with chimeric antigen receptor T-cells”
2:35-3:25 PM
Oral Presentations – Session II (Oval Theater)
Moderator: Dr. Evan Wuthrick
Dr. Thales Nepomuceno “A comprehensive analysis of BRCA1 frameshift variants leading to extended incorrect protein termini”
Alyssa Obermayer “Transcriptome analysis and machine learning identify therapeutic strategies for high-risk pediatric AML patients of the KMT2A-fusion subgroup”
Devesh Raizada “Age-induced chronic accumulation of cortisol drives therapy resistance in lung cancer”
Dr. Fnu Sathyanarayana Neelature “To define how the uvel melanoma-liver environment crosstalk shapes metastasis growth and therapeutic response”
Dr. Leticia Tordesillas “Biodistribution of zoledronate and effects on gamma delta PSCA-CAR T cells in a model of bone metastatic prostate cancer”
3:25-3:40 PM
Awards and Closing Remarks, Dr. Jong Park & Dr. Evan Wuthrick (Oval Theater)
TRANSPORTATION
A Moffitt shuttle bus will be running a continuous route between Moffitt and the USF Marshall Center on Wednesday, May 17th from 7:30AM-4:00PM. You may also choose to walk or drive your personal vehicle if you have an appropriate USF parking permit.
Please see map below for exact shuttle stop locations
Shuttle stop =
POSTER MAP
Featured Posters 001-015 001 007 006 005 004 003 002 026 020 021 022 023 024 025 013 012 011 010 009 008 014 015 016 017 018 019 027 033 032 031 030 029 028 052 046 047 048 049 050 051 053 059 058 057 056 055 054 078 072 073 074 075 076 077 079 085 084 083 082 081 080 104 098 099 100 101 102 103 105 111 110 109 108 107 106 130 124 125 126 127 128 129 131 137 136 135 134 133 132 156 150 151 152 153 154 155 039 038 037 036 035 034 040 041 042 043 044 045 065 064 063 062 061 060 066 067 068 069 070 071 091 090 089 088 087 086 092 093 094 095 096 097 117 116 115 114 113 112 118 119 120 121 122 123 143 142 141 140 139 138 144 145 146 147 148 149 169 168 167 166 165 164 170 171 172 173 174 175 195 194 193 192 191 190 196 197 198 199 200 201 157 163 162 161 160 159 158 182 176 177 178 179 180 181 183 189 188 187 186 185 184 208 202 203 204 205 206 207
USF Marshall Student Center Ballroom
MOFFITT SCIENTIFIC SYMPOSIUM FREQUENTLY ASKED QUESTIONS (FAQ)
1. Where is the Symposium located?
Tuesday, May 16th, 2023 - the W. Jackson Pledger Researcher of the Year lecture will take place in the Stabile Research Building (SRB) Ted Couch Auditorium followed by a reception in the SRB Murphy conference room.
Wednesday, May 17th, 2023 - all activities will be at the USF Marshall Student Center.
2. Can I attend if I did not RSVP?
Yes, we prefer that everyone RSVPs, but you can still attend if you forgot. Link to RSVP: https://www.surveymonkey.com/r/B9R3ZDW
3. How can I get to the Marshall Center? Is there parking?
Reserved parking has been set aside for featured posters, oral presenters, committee members and speakers only. General attendees should walk to the Marshall Center or take the Moffitt shuttle which will be continuously running between Moffitt and the Marshall Center. Please review the transportation page in this guide for shuttle locations and times.
4. How do I know what poster session I can find certain presenters?
This guidebook shows the poster number for every presenter. The poster sessions are divided up by odd numbered posters (poster session #1) and even numbered posters (poster session #2).
5. Is there Wi-Fi available at the Symposium?
Wireless access is provided to guests of USF. Please follow these directions:
1.) Open your list of wireless connections on your device and select “USF-Guest”
2.) Once you are connected, open your web browser and attempt to navigate to a website. You will automatically be redirected to the Guest Registration page
3.) On this page, select your preferred method of contact. Either “call me on my phone” or “send me a text message”
4.) You will receive a temporary access code within 5 minutes. Select the option “I have my access code”. You will need to agree to the acceptable use policy to continue
5.) Enter your mobile phone number and the registration code you received and hit “submit”
6.) You are now connected to the USF-Guest network. The registration will last for 24 hours and is valid for 1 device.
6. What will the food options be?
May 16th Reception: selection of hors d’oeuvres including vegetarian, vegan, and gluten free options with beer/wine bar
May 17th Breakfast: assorted muffins, scones, danish, fresh fruit, coffee, juice, and tea
May 17th Lunch: assorted sandwiches and wraps including vegan, vegetarian, and gluten free options, garden salad, potato salad, assorted desserts, and lemonade
Water and coffee will be available all day in the Ballroom on May 17th
7. How do I vote for the People’s Choice award?
Everyone who attended the Symposium on May 17th (and signed in at the registration desk) will receive an electronic ballot via email on May 18th. Deadline to vote is Friday, May 19th by 5PM. The winner will be announced in Signals the week of May 22nd. Featured Poster presenters and Oral presenters are not eligible for the People’s Choice award
FEATURED POSTERS
Presenter Title (mentor) Poster # Luis Aguirre Validation of the Molecular International Prognostic Scoring System (IPSS-M) Risk Stratification Model for Myelodysplastic Syndromes (Komrokji) 001 Cherell Cottrell-Daniels Associations of Cancer Treatment Status on Smoking Cessation Among Survivors of CIN or Cervical Cancer (Vidrine) 002 Ou Deng PARP16 modulates MYC expression and susceptibility of Ewing’s Sarcoma cells to PARP1 inhibition (Rix) 003 Ammoren Dohm Upfront Osimertinib Alone Versus Osimertinib and Radiotherapy for the Treatment of EGFR-positive NSCLC Brain Metastases: A Multi-institutional Series (Ahmed) 004 Thomas Dombrowski Tumor-immune ecosystem dynamics exploration via a high-resolution agent-based model (Enderling) 005 Saurabh Garg The correlation of oncodriver expression with tumor infiltrating lymphocytes in triple negative breast cancer (TNBC) (Czerniecki) 006 Rebecca Hesterberg Aging dampens lymphoma-provoked phenotypic and epigenomic changes to the adaptive immune system (Cleveland) 007 Filip Ionescu Fludarabine Exposure Impact on Safety and Efficacy of Idecabtagene Vicleucel in Relapsed/Refractory Multiple Myeloma (Hansen) 008 Daria Miroshnychenko Stroma-induced cancer cell proliferation accelerates tumor recovery between chemotherapy cycles (Marusyk) 009 Mostafa Nasr PRDM16: A key switch enabling long
skeletal dormancy and survival in prostate cancer (Lynch) 010 Eleonora Pelle A novel hormone-based anti-SSTR T-cell engager for the treatment of neuroendocrine tumors (Strosberg) 011 Jennifer Perone Evaluation of an Intraoperative Critical Event (ICE) Team at a Major Cancer Center (Gonzalez) 012 Marilena Tauro Novel autophagy inhibitory strategies to treat multiple myeloma. (Lynch) 013 Malgorzata Tyczynska-Weh Modeling selection for evolvability in the evolution of cancer therapy resistance (Basanta) 014 Tomas Zelenka Bcl11b is a bimodal switch between stem-like and effector Trm cells in infection and tumor (Avram) 015
term
BASIC SCIENCE POSTERS
Listed alphabetically by last name Presenter Title (mentor) Poster # Suehelay Acevedo Acevedo Determining the role of ΔNp63 in lung adenocarcinoma progression (Flores) 104 Santanu Adhikary Delta Np63 drives metabolic reprogramming in breast cancer via long noncoding RNAs (Flores) 156 Hasan Alhaaddad Meningeal stroma–tumor cell crosstalk promotes tumor growth and drug resistance in melanoma leptomeningeal metastasis (Smalley) 069 Anika Ali Deciphering the link between translational dynamics and HLA-I antigen presentation (Jaeger) 183 Parisa Amirifar Functional and biological heterogeneity of Oncogenic KRAS G12 Alleles in Non-Small Cell Lung Cancer (NSCLC) (Kissil) 026 Rafael Bravo Using MRI scans to predict tumor margin propagation in GBM under immunotherapy (Anderson) 147 Chase Burton L-fucose enhances anti-tumor immunity through modulation of monocyte-derived dendritic cell signaling (Lau) 064 Daiana Celias Investigating the mechanisms involved in HMGB1dependent DNA uptake and STING activation in dendritic cells (Ruffell) 030 Manon Chadourne Evidence of glycosylated RNA in melanoma and melanocytes cell lines (Karreth) 094 Neelkamal Chaudhary An Imaging flow cytometry-based analysis of small extracellular vesicles in platelet-poor plasma samples from healthy donors and cancer patients (Rodriguez) 117 Janine DeBlasi Distinct NRF2 signaling thresholds mediate lung tumor initiation and progression (DeNicola) 152 Avani Deshpande TROLL-9 as a novel tumor suppressor in breast cancer (Flores) 057 Michael Emmons Epigenetic regulation of brain metastasis formation in stress-resistant melanomas (Smalley) 062 Jeremy Frieling Elucidating reciprocal interactions between bone marrow stromal cells and γδ CAR T cells in the context of bone metastatic prostate cancer (Lynch) 027 Wael Gamal Metabolic Dysregulation in CLL T cells (Pinilla-Ibarz) 084 Miguel Gomez Fontela Killer cell immunoglobulin-like receptor 2DL2 (KIR2DL2) immune checkpoint modulates CAR-T cell effector function (Abate-Daga) 041 Maria Gonzalez- Rodriguez Combined inhibition of BET proteins and FAK1 as a novel therapeutic strategy for Neurofibromatosis Type 2-related Schwannomas (Kissil) 207 Michael Grant The Role of ITCH in CD8+ T-Cell Activity and The Melanoma Tumor Microenvironment (Wan) 171 Crystal Griffith CDH3 functions as a melanoma suppressor and its expression is affected by Long Non-coding RNA CDH3-AS1 (Karreth) 097
Kay Hänggi Necroptosis promotes tumor growth through IL1-alpha release and recruitment of immunosuppressive myeloid cells (Ruffell) 048 Qianqian Hu Cancer-associated fibroblasts confer ALK TKI resistance via MET and integrin signaling in ALK-rearranged lung cancer (Rix) 159 Briley Humphrey Synthesis of Inhibitors and PROTACs as Chemical Probes for the Biological Evaluation of JAK2 Inhibition and Degradation (Lawrence) 119 Mohammad Ibrahim Sotorasib indirectly promotes antitumor T cell immunity and enhances immunotherapy response through enrichment of TNFα and IFNγ signals in G12C-KRAS mutant cancer cells. (Beg) 136 Neel Jasani BRAF- mediated PHGDH induction establishes a metabolic vulnerability in melanoma (Karreth) 194 Rachel Jimenez The Unfolded Protein Response as a Novel Therapeutic Target in Leptomeningeal Disease and Brain Metastases (Rodriguez) 090 Hossein Kashfi Quinolinic acid phosphoribosyl transferase (QPRT) is an essential liability of non-small cell lung cancer (Gomes) 187 Anna Koktysh IND enabling studies for rare skin cancer targeted alpha particle therapy (Morse) 019 Felicia Lazure The effect of CD320-mediated vitamin B12 uptake in breast cancer transformation (Gomes) 073 Daniel Lester HLA-DRB1 fucosylation regulates CD4+ T cell mediated anti-melanoma immunity and enhances immunotherapy efficacy (Lau) 164 Jie Li Evaluate targeting ENPP1 in combination with PARPi to boost anti-tumor immunity in TNBC (Ruffell) 160 Yi Liao Integrative and differential network analysis unravels lorlatinib polypharmacology in ROS1-positive NSCLC by cotargeting PYK2 (Rix) 049 Jay Lockhart Guided integrated spatial multi-omics in archival tissue of lung adenocarcinoma models using machine learning (Flores) 129 Mariam Lotfy Khaled Branched-chain keto acids exert an immune-suppressive and neurodegenerative microenvironment in CNS leptomeningeal lymphoma (Smalley) 095 Ashley Lui RNA Based Therapeutics to target the p53 pathway in cancer: TAp63-Regulated Oncogenic LncRNAs (TROLLs) as novel therapeutic targets in cancer (Flores) 197 J Mandula Jagged2 targeting in lung cancer activates anti-tumor immunity via Notch-induced functional reprogramming of tumor-associated macrophages (Rodriguez) 208 Renata Marques Rossetti CD40L stimulates melanoma infiltrating B cells and enhances ex vivo TIL expansion (Abate-Daga) 145 Michael Martinez Elucidating the MAFG interactome in melanoma (Karreth) 020 Elena Martinez Planes IL-2-inducible T-cell kinase (ITK) is required for CD28 Y218 phosphorylation, an essential residue for IL-2 secretion and antitumor effect of CAR-T cells. (Abate-Daga) 036 Angelie Matar Optimization of ACK1 Inhibitors Utilizing a Pyrrolopyrimidine Scaffold (Lawrence) 082
Jenet Matlack Molecular mechanisms governing substrate specificity in mammalian deglycation pathways (Binning) 016 Nicol Mecozzi Investigating the metastatic potential of circPMS1 in melanoma (Karreth) 035 Marco Napoli Metabolic reprogramming drugs as a novel therapeutic strategy to target the p53 pathway in cancer (Flores) 053 Niveditha Nerlakanti Oncogenic role of Neuropilin-1 in osteosarcoma growth and metastasis (Lynch) 022 Alexis Onimus HMGB1 release predicts chemotherapy combinatorial efficacy with TIM-3 blockade (Ruffell) 196 Omotayo Osunmakinde Investigating cholesterol transfer between macrophages and prostate cancer cells (Ruffell) 028 Thiyagu Pandurangan Discovery and optimization of novel imidazo[1,2-b] pyridazine analogues as potent CDK12 inhibitors for the treatment of TNBC (Monastyrskyi) 042 Taylor Peak Alterations in RNASET2 Impact the Pathogenesis of Clear Cell Renal Cell Carcinoma (Manley) 188 Manali Phadke The anti-PD1+anti-LAG3 and anti-CTLA4+anti-PD1 combinations have non-overlapping mechanisms of action in melanoma cranial and extra cranial metastases. (Smalley) 055 Marine Potez Using hypoxia to improve Tumor Infiltrating Lymphocytes therapy in different subtypes of renal cell carcinoma (Pilon-Thomas) 045 Rafael Renatino Canevarolo The multiomic landscape of the evolution of the Warburg effect identifies drivers of breast cancer (Silva) 066 Jyoti Srivastava Role of Acetyl Zingerone and Its Derivatives in Inhibiting UV-Induced DNA Damage (Premi) 043 Joanne Tejero Methylmalonic acid accumulation suppresses CD8+ T cell activation and contributes to age-induced immunosuppression (Gomes) 067 Laura Torrente Fernandez Aberrant activation of NRF2 in NSCLC confers sensitivity to copper starvation (DeNicola) 029 Benito Traversa Chronic upregulation of glucocorticoid hormones triggers chromatin remodeling in NSCLC through dynamic regulation of Histone H3 chaperones (Gomes) 204 Preethi Varughese Development of the Cu-64-MTI-201 Companion PET Imaging Tracer for Ac-225-MTI-201 Targeted AlphaParticle Therapy (Morse) 146 Torus Washington Bowls aren’t just for cereal: Silica Nanobowl drug delivery for effective lung cancer treatment (Morse) 017 Andrew Weeden Engineering new mouse models to study antigen presentation in vivo (Jaeger) 165 Gabriela Wright Loss of CX3CL1 expression mediates immune evasion in STK11 mutated lung adenocarcinomas (Cress) 040 Shengyan Xiang Human CMG Helicase ATPase Domains Stabilize Replisome Structure to Prevent DNA Damage (Alexandrow) 185 Xiaonan Xu Understand the metastasis of uveal melanoma in vivo via novel mouse models (Karreth) 092 Vipin Yadav NRAS-mutant melanoma sensitized to MEKi in response to nitrosylation inhibition (Premi) 174
Maya Yasukawa HIRA is an epigenetic regulator that underlies chemotherapy resistance in ovarian cancer (Gomes) 074 Sang Jun Yoon Mechanism and role of non-canonical cystathionine synthesis in cancer (DeNicola) 058
CLINICAL SCIENCE POSTERS
Listed alphabetically by last name Presenter Title (mentor) Poster # Othman Akhtar Safety and Efficacy of Anti-BCMA CAR-T Cell Therapy in Older Adults with Multiple Myeloma: a Systematic Review and Meta-analysis (Freeman) 140 Kate Beekman Radar-Guided Localization for Melanoma Metastasectomy (Zager) 115 Nicholas Champion Surgeon and Radiologist Evaluation of Electromagnetic Chip Localization for Breast Conservation Surgery (Lee) 191 Ruben Cruz-Chamorro Outcomes of Patients with Radioresistant Brain Metastases treated with Fractionated Stereotactic Radiotherapy alone or Surgery followed by Fractionated Stereotactic Radiotherapy (Yu) 052 Claire Dalby Effects of Preoperative Diabetes Mellitus on Postoperative Outcomes after Robotic-Assisted Video-Thoracoscopic Pulmonary Lobectomy (Toloza) 075 Danielle Depalo Intralesional therapy, limb infusion/perfusion, and immune checkpoint inhibitors as first-line therapy in surgically unresectable melanoma in-transit metastases (Zager) 113 Justin Drake Progressive Improvements in Postoperative Outcomes with Over 500 Robotic Transthoracic Esophagectomies at a Single Institution (Sinnamon) 143 Dereen Duhoki Usual and Underrecognized Histomorphology of Pancreatic Ductal Adenocarcinomas Associated with Preoperative Neoadjuvant Management (Jiang) 180 Kelly Elleson Features of Breast Cancer Nodal Metastasis (Lee) 149 Katherine Englander Factors Influencing Lymph Node Positivity in HER2.neu+ Breast Cancer Patients (Lee) 144 Julia Gallagher Factors Associated with Node-Positive Disease in Estrogen Receptor-Positive (ER+) Breast Cancer Patients (Lee) 134 Vivian Irizarry Gatell Clinical Outcomes of Adults Undergoing Allogeneic Stem Cell Transplant for Secondary Acute Lymphoblastic Leukemia (Faramand) 054 Richard Jacobson Safety and efficacy of diagnostic laparoscopy in patients with colon peritoneal metastases: A contemporary analysis (Dineen) 202 Akriti Jain Post-allogeneic Stem Cell Transplant Outcomes in Patients treated with Hypomethylating Agent plus Venetoclax Compared to CPX-351 (Sweet) 162 Grace Johnson Remissions endure despite B-cell recovery following antiCD19 CAR T therapy for DLBCL in a single-center study (Jain) 166 Vaseem Khatri An Assessment of Toxicity with Pelvic Radiotherapy following Prostate Artery Embolization: a single-institution retrospective review (Parikh) 032 Tiffani Mathew Adenosquamous Carcinoma (ASC) of the Head and Neck (HN): A Comparative and Molecular Study of HPV050
Associated and HPV-Independent Tumors (HernandezPrera) Christine Mau Efficacy of Kyphoplasty alone versus Kyphoplasty and Radiofrequency Ablation on Osteoblastic Lesions in Breast Cancer patients: A Single-center 10-year experience (Tran) 101 Virginia Mazack Detecting Uncommonly Long FLT3 ITD Mutations in AML (Qin) 150 James McDonald Hospital surgical volume is poorly correlated with delivery of multimodal treatment for localized pancreatic cancer. A national retrospective cohort study. (Powers) 024 Ruoyu Miao Biomarker Analysis to Predict Response in Patients with Metastatic Mismatch Repair Proficient Colorectal Cancer Treated with Regorafenib and Nivolumab (Kim) 033 Turab Mohammed Incidence and risk factors associated with bleeding following anti-B cell maturation antigen chimeric antigen receptor T-cell therapy in patients with relapsed/refractory multiple myeloma (Hansen) 130 Razan Mohty Hematopoietic Recovery after Anti-B Cell Maturation Antigen (BCMA) Chimeric Antigen Receptor T Cell Therapy (CAR T), Idecabtagene Vicleucel (Ide-cel), for Relapsed/Refractory Multiple Myeloma (RRMM) (Hansen) 181 Prithvi Murthy Survival Benefits of Adjuvant Chemotherapy for Positive Soft Tissue Surgical Margins Following Radical Cystectomy in Bladder Cancer with Extravesical Extension (Li) 079 Justyn Nakashima Outcomes of Patients with Transformed Diffuse Large BCell Lymphoma (DLBCL) (Kim) 199 Nour Nasser Feasibility of Novel Low Dose Radiation Treatment of Polymetastatic disease in Stage IV NSCLC Patients Receiving Systemic Immunotherapy to Improve Response (Redler) 089 Nayeon Oh An Analysis of Patients Treated with Stereotactic Body Radiotherapy for Metastatic Urinary Tract Tumors to Identify Predictors of Response (Grass) 044 Hilal Ozakinci Molecular subtyping of donated small cell lung carcinoma samples with a clinical targeted expression panel (RNA step) (Boyle) 021 Robin Park Association of Neutrophil-Lymphocyte Ratio (NLR) with Clinical Outcomes in Patients (pts) with Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) Treated with Combination of Cetuximab and Nivolumab (C+N) (Chung) 201 Maulik Patel MRI for prediction of pCR in patients with HER2+ Breast Cancer Treated with Neoadjuvant Immunotherapy Followed by Neoadjuvant Chemotherapy (Weinfurtner) 157 Matthew Perez Management of primary anorectal mucosal melanoma in the era of modern systemic immunotherapy and targeted therapy (Zager) 078 Yanet Prieto Carratala Idylla MSI assay for fast patient screening to identify candidates for immunotherapy (Bossler) 206 John Puskas Clinical Validation of a Comprehensive RNA-based Solid Tumor Fusion Extended (SafireX) Panel (Boyle) 195
Ryan Putney Methylation-Driven Gene Expression Differences in African American and European American Men (Yamoah) 102 Elena Ryzhova Validation of Idylla™ EGFR Assay for rapid detection of EGFR mutations in patients’ FFPE tissues (Bossler) 137 Lamees Saeed HER2 Interpretation Reproducibility in HER2-low Breast Cancer (Rosa) 065 Danial Shaikh Differences in gender and overall survival for temperaturesensitive TP53 mutations in a gastroesophageal cancer (Mok) 148 Marian Smallin The Chromosome 19 MicroRNA Cluster Suppresses T Cell Immunity in Cancer Tissues (Brohl) 131 Wenxin Song Group Piano Training on Quality of Life and Cognition in Patients with Cancer (Mallory) 034 Sean Stokes Practice Patterns and Outcomes of Acute Care Surgery in Cancer Patients (Dineen) 098 Caleb Streitmatter A pilot randomized controlled trial comparing preanesthesia evaluation via telemedicine versus in-person for surgical patients at H. Lee Moffitt Cancer Center (Aldawoodi) 155 Ram Thapa Statistical Analysis Tool for Oncore-Generated Adverse Event (AE) Data (Chen) 177 Amber Valeri Hydrocephalus in Leptomeningeal Disease: Ommaya Reservoir-Shunt for Intrathecal Chemotherapy Administration (Tran) 127 Ricardo Villanueva High metabolic tumor volume and its association with higher toxicity and decreased efficacy of BCMA CAR-T cell therapy in multiple myeloma (Freeman) 151 Yan Wang How many were missed: originally undiagnosed microsatellite unstable gastrointestinal carcinomas? (Jiang) 154 Shawna Watson Increased mechanical implant failures with combined Type III pelvic resections for reconstruction of periacetabular pelvic tumor resections using patient-specific implants (Joyce) 100 Junmin Whiting Discovery of Predictive Gene Signatures for Combining Chemotherapy with Avastin in Metastatic Colorectal Cancer (Chen) 060 Keith Wirth Tumor burden and liver specific survival after resection +/ablation of multifocal colorectal liver metastasis (Denbo) 123 Jodie Wong Targeted cell-free DNA methylation signature in metastatic castration-resistant prostate cancer (Wang) 114 James Yu Biomarker analysis from a phase I/Ib study of regorafenib and nivolumab (rego/nivo) in microsatellite stable (MSS) colorectal cancer (CRC) (Kim) 205 Jennifer Zhou Treatment of Stage III Melanoma in the Post MSLT-II era: A literature review (Wuthrick) 161
POPULATION SCIENCE POSTERS
Listed alphabetically by last name Presenter Title (mentor) Poster # Hannah Alex Disparities in financial and psychological health outcomes amongst informal cancer caregivers during the COVID-19 pandemic (Byrne) 046 Rossybelle Amorrotu Approaches to estimate real-world disease progression in lung cancer (Rollison) 108 Laura Casas Hispanic/Latinx individuals’ attributions for abstinence and smoking: A content analysis of open-ended responses from a randomized cessation trial (Simmons) 184 Paulo Cilas Morais Lyra Junior Integration of functional data to classify BRCA2 missense variants: an ENIGMA project (Monteiro) 192 Diana Diaz Bright IDEAS-Young Adults: Problem-Solving Skills Training to Reduce Distress among Young Adults with Cancer (Donovan) 109 Cassandra Hathaway The Association of Kidney Function Biomarkers with Ovarian Cancer Risk and the Mediating Effects of Inflammation (Tworoger) 105 Heather Huelster Cost-effectiveness of Initial Management of High-grade T1 Bladder Cancer with Intravesical BCG vs Immediate Radical Cystectomy (Gilbert) 163 Khushali Jhaveri 20-year Incidence Trends of Anal Squamous Cell Carcinoma (Kim) 121 Charles Lacson Predictors of correct recall of MC1R genetic risk among Hispanic individuals participating in a skin cancer precision prevention trial (Kanetsky) 023 Paige Lake Family history and quality of life (QOL)-related factors associated with Adolescent and Young Adult (AYA) cancer patient requests for fertility consultations (Vadaparampil) 091 Ursula Martinez Pradeda Feasibility and Acceptability of a Targeted Self-Help Intervention to Increase Motivation to Quit Smoking among Oncologic Patients (Simmons) 203 Samantha Montoya REAL World Implementation of Colorectal Cancer Screening (Gwede) 198 Gazelle Rouhani Neighborhood Socioeconomic Disadvantage and Survival Outcomes Among Patients with Colorectal Cancer: Results from the ColoCare Study (Siegel) 063 Alon Rozental Feasibility of chimeric antigen receptor T-cell therapy in very old patients with relapsed/refractory diffuse large Bcell lymphoma: a single center analysis (Extermann) 031 Bethany Shorey Fennell Perceptions of the proposed FDA graphic cigarette warnings among daily and nondaily smokers (Vidrine) 120 Nathanael Stanley Simultaneous Visualization of Spatial and Temporal Trends of Cancer Incidence (Vadaparampil) 107 Yijun Tian Combined CRISPRi and Proteomics Screening Reveal a Cohesin-CTCF-bound Allele Contributing to Increased Expression of RUVBL1 and Prostate Cancer Progression (Wang) 070
Min-Jeong Yang Qualitative Evaluation of the Implementation and Future Sustainability of an E-referral System for Smoking Cessation at Moffitt Cancer Center: Lessons Learned (Simmons) 086 Shahrzad Zamani Understanding the Disparities and Cancer Care Challenges Among Sexual and Gender Minority Patients (Schabath) 132
QUANTITATIVE SCIENCE POSTERS
Listed alphabetically by last name Presenter Title (mentor) Poster # Shatha Abudalou Deep Neural Network Architecture to detect Prostate Anatomy (Balagurunathan) 071 Richard Beck Charting the fitness landscape of genomic copy number alterations (Andor) 186 Rebecca Bekker Black Holes in TIME: the Effect of GRID Radiation on the Tumor-Immune Micro-environment (Enderling) 128 Thanh Duong Cancer Comprehend Annotation – a pipeline for cancer phenotype and bioinformation extraction (Thieu) 189 Matthew Froid A Hybrid Machine Learning and Agent-Based Modeling Approach Illuminates Physical and Genetic Factors Contributing to Resistance in the AML Bone Marrow Niche (Basanta) 168 Kit Gallagher Learning to Adapt - Deep Reinforcement Learning in Treatment-Resistant Prostate Cancer (Anderson) 059 Jill Gallaher Predicting progression in metastatic castrate-sensitive prostate cancer by coupling PSA and testosterone dynamics to a mechanistic mathematical model (Anderson) 025 Daniel Glazar A sample size analysis of a joint model of longitudinal tumor volume and progression-free survival in an in silico glioma clinical trial (Enderling) 158 Anjun (Angela) Hu Modeling of macrophages – breast tumor interactions under ER inhibitors in 3D Microenvironments (Rejniak) 056 Alex Johnson Comparing Prostate Specific Antigen Dynamics Between Black Patients and White Patients (Brady Nicholls) 068 Tuan Dung Le Leveraging deep active-transfer learning to identify mobility functioning information in clinical text (Thieu) 018 Xiang Liu An epigenomic fingerprint of human cancers by systematically modeling super enhancer divergence (Teng) 125 Gabrielle Nobles Developing a Single-Cell RNA-seq Reference Database for Primary and Metastatic Brain Cancer (Shaw) 085 Maureiq Ojwang Using digitized histology images to assess the hindering effects of hypoxia on T cell infiltration in orthotopic bladder tumors in mice (Rejniak) 126 Kayode Olumoyin A Machine Learning Predictor of the Expansion of Tumor Infiltrating Lymphocytes in Patients’ Bladder Tumors (Rejniak) 047 Stefano Pasetto Calibrating tumor growth and invasion parameters with spectral-spatial analysis of cancer biopsy tissues (Enderling) 111 Sandhya Prabhakaran Agent-based model to study autocrine signaling effects in NSCLC following an active immune response (Anderson) 110 Mark Robertson-Tessi The evolution of T-cell receptors in the context of viruses, cancer, and self-antigens (Anderson) 135
Kirill Sabitov Exploring the Spatial Architecture of the Tumor-Immune Microenvironment in Papillary Renal Cell Carcinoma (Fridley) 080 Arpan Sahoo Intrinsic disorder of blood-sourced TRB V-CDR3-J sequences correlates with a greater survival probability for uveal melanoma (Blanck) 112 Alex Soupir Spatial context of spatial molecular imaging aids in identification of differences between immunotherapy responders and non-responders in clear cell renal cell carcinoma (Fridley) 182 Praneeth Sudalagunta A Novel Gene Regulatory Network Model Identifies Novel Therapeutic Targets in MM (Silva) 106 Talha Syed Comparing the Capacity of 3 Mathematical Models to Forecast Tumor Volume Dynamics and Predict Individual Head and Neck Cancer Patient Responses to Radiotherapy. (Enderling) 087 Zachary Thompson Drepmel A Multi-Omics Melanoma Drug Repurposing Resource for Prioritizing Drug Combinations and Understanding Tumor Microenvironment (Chen) 037 Thomas Veith Investigating the effects of frequency and densitydependent selection on cancer cells (Andor) 172 Zhouping Wei Deep Neural Network Architecture to detect Prostate Anatomy (Balagurunathan) 061 Joseph Weygand Accurate, repeatable, and geometrically precise diffusion imaging on a 0.35 T MRI- guided linear accelerator (Redler) 081 Mohammad Zahid Proliferation Saturation Index to Simulate Adaptive Radiation Fractionation in HPV-Associated Oropharyngeal Cancer (Enderling) 175
TRANSLATIONAL SCIENCE POSTERS
Listed alphabetically by last name Presenter Title (mentor) Poster # David Adams Patient Stratification for Wilms Tumor Using Physical and Chemical Properties of the Adaptive Immune Receptors IGL and TRG (Blanck) 138 Aileen Alontaga Comprehensive Tumor Profiling Reveals High Concordance of Gene Amplification with RNA Expression (Boyle) 093 Sarah Bazargan Modulating the Immune Microenvironment in Bladder Cancer to Enhance Efficacy of Adoptive Cell Therapy (ACT) (Pilon-Thomas) 051 Matthew Beatty Expansion and identification of neoantigen reactive tumor infiltrating lymphocytes (TIL) from metastatic colorectal cancer (CRC) (Pilon-Thomas) 173 Liz Bridenstine Mutations in CTNNB1 can regulate resistance in EGFR Targeted Therapies for Non-Small Cell Lung Cancer (Haura) 118 John Michael Bryant A novel multi-task (parallel) hybrid deep neural network predicts tumor progression during MRgRT compared to traditional delta radiomics (Rosenberg) 124 Andrew Chang Proteogenomic, epigenetic and clinical implications of recurrent aberrant splice variants in clear cell renal cell carcinoma (Manley) 038 Erika Eksioglu Improvement of hematopoiesis in low risk MDS with the Alk5 inhibitor TP-6379 improves hematopoiesis of primary low risk MDS and S100A9Tg mice (Wright) 072 Veronica Estrella Characterization of humanized nanobodies that bind to CAIX and CAXII for use in the detection of breast cancer metastasis (Morse) 122 Curtis Gravenmier B-Lymphoblastic Leukemia Subpopulation Dynamics Predict BCR::ABL1 and Philadelphia-Like Status, PostInduction Minimal Residual Disease, and 3-Year Relapse (Zhang) 153 Imene Hamaidi Sirt2 regulates the proximal T cell receptor signaling (Kim) 200 Denis Imbody Wildtype RAS Activity and PI3K Signaling as New Vulnerabilities in Cells with Acquired Resistance to Sotorasib (Haura) 077 Ryoji Kato RAS:RAF proximity ligation assay may predict response to KRASG12C inhibitors in NSCLC (Haura) 169 Shrikar Modukuri The CDK12/13 inhibitor SR-4835 prevents acquired resistance to the KRASG12C inhibitor adagrasib (Haura) 103 Nina Obertopp Radiation enhances ex vivo expansion of tumorinfiltrating lymphocytes (TIL) (Pilon-Thomas) 083 Ibrahim Oraiqat Real-time, volumetric imaging of radiation dose delivery deep into the liver during cancer treatment (El Naqa) 088
Garima Pandey SHP2 Inhibition Suppresses RAS-ERK Signaling, the Development of JAK2 Inhibitor Persistence, and Disease Progression in Pre-Clinical Models of Myeloproliferative Neoplasms (Reuther) 193 Kyle Rose Cell-free urinary tumor DNA to detect minimal residual disease prior to repeat-transurethral resection of bladder tumor in non-muscle invasive bladder cancer: a prospective study (Li) 141 Hitendra Solanki SHP2i combination with Sotorasib effectively target KRASG12C tumors developing secondary resistance to Sotorasib via KRASG12C amplification (Haura) 167 Joanna Song Hepatocellular carcinoma adaptive immune receptor profiling and association of electrostatic complementarity between CDR3 and hepatitis C viral epitopes with increased survival probabilities (Blanck) 099 Yaakov Stern Targeting CDK12/13 suppresses diverse paths to KRASG12C inhibitor resistance in NSCLC (Haura) 178 Angimar Uriepero Palma S100A9 as a novel immunotherapeutic target in Chronic Lymphocytic Leukemia (Pinilla-Ibarz) 176 Hong Zheng Development and early clinical testing of IFNβ and membrane-stable CD40L expressing oncolytic virus to maximize systemic T cell immunity through dendritic cell activation and lymph node trafficking (Beg) 116 Zhong Zheng Validation of Low Limit of Detection for Myeloid Action 98 Gene Panel (MAP98) for Residual Disease Monitoring (Bossler) 142
MOFFITT SCIENTIFIC SYMPOSIUM COMMITTEE
Dr. Jong Park (Co-Chair)
Dr. Evan Wuthrick (Co-Chair)
Dr Yoga Balagurunathan
Dr. Leidy Isenalumhe
Dr. Zena Jameel
Dr. Estefania Julia
Dr. John Mullinax
Dr. Russell Palm
Dr. Gage Redler
Dr. Katarzyna Rejniak
Dr. Maria Sandoval
Dr. Michael Shafique
Dr. Vani Simmons
Dr. Lixin Wan
Dr. Liang Wang
EVENT COORDINATORS
Angela Reagan
Kassie Morehouse
