Māori & Pacific Peoples’ Health Research Strategy

Led by MRINZ deputy director, Associate Professor Matire Harwood, a respected leader in Māori health research, we have recognised the need for novel strategies for Māori engagement in our research, and using these have seen a markedly reduced inequality in terms of participant representation.

Recognition of the interdependencies of social, economic and health outcomes in Aotearoa New Zealand’s Māori population is key to developing and conducting large scale, high impact research programmes working to reduce inequalities across these domains.

In addition to conducting traditional forms of research such as randomised controlled trials (RCTs) with Māori participants, the MRINZ is increasingly engaging in collaborations across multiple sectors providing expert clinical advice. Many of these stem from economic development programmes exploring the use of bioactives and have a long history of use within Rongoā Māori, the traditional healing system of Māori.

The MRINZ’s evolving Māori Research Strategy presents measurable objectives for the MRINZ in the areas of workforce development, collaboration in randomised clinical trials, and conducting research that is culturally safe in its methodology and trial conduct. Highlights include the appointment of a Māori Health Advisor, Māori research fellows, Māori medical students as interns, and funding applications with Māori Principal Investigators. The recruitment of Māori participants into clinically and culturally safe research trials contributes to better knowledge and practice and ultimately equitable health outcomes.

In its two-decade history, the MRINZ has conducted numerous RCTs with Māori participants to examine key Māori health issues such as smoking cessation therapy, asthma, stroke, and the care of critically ill patients. Equity in health outcomes were achieved during the research and the findings have been translated into clinical practice through guidelines and presentation, thereby contributing to ongoing health benefits for Māori.

Through the development of novel clinical trial platforms using informatics integrations with the electronic health record, smartphone technology and national pharmacy and general practice localities we are achieving Māori participation of over 13%, a significant increase in previous general population studies. Harnessing this improved research engagement provides significant potential in both assessing and improving Māori health outcomes.

MRINZ works with kaupapa Māori researchers, service providers and experts in ways that have enhanced the application of Māori methodologies in health research. Mahi is ongoing in developing our workforce to apply kaupapa Māori methods to trial development, participant recruitment, data collection methods, dissemination, and translation in widespread clinical practice. In order to facilitate this, we have actively partnered with Māori trusts and academic institutions to promote paid student internships, salaried Masters and PhD places in clinical research and research assistant positions amongst New Zealand communities.

Leveraging innovative methodologies that allow usual care providers to participate in RCTs throughout New Zealand, not just in major centres, is key to both accessing and engaging patient groups and subsequent translation of findings to deliver whānau ora. This includes provision of a translation facility to promote the use of te reo in all study patient information.

In addition, understanding patient perspectives is an important and increasingly recognised role in protocol development. As such we actively seek Māori patient advocacy involvement in conjunction with Te Whatu Ora — Capital, Coast and Hutt Valley research Advisory Group — Māori review for all studies.

Ketuketua ngā āhuatanga o te ao kikokiko e hukea ai ngā kura huna! He aha ēnei kura huna? Ko te oranga o Ngāi Māori!

Improving Māori health is why I chose to enter into the medical profession. I see research as the best way to improve Māori health on a wide scale, and being part of the MRINZ team has meant that I have been fortunate enough

2023

1. Armour M, Sinclair J. Cannabis for endometriosis-related pain and symptoms: It’s high time that we see this as a legitimate treatment. Aust N Z J Obstet Gynaecol 2023; 63: 118-20.

2. Beasley R. Every action matters, every bit of warming matters. Respirology 2023; 28: 287-8.

3. Beasley R, Bruce P, Hatter L. ICS/ formoterol maintenance and reliever therapy: how far beyond asthma? Thorax 2023; 78: 430-1.

4. Beasley R, Bruce P, Houghton C, Hatter L. The ICS/formoterol reliever therapy regimen in asthma: a review. J Allergy Clin Immunol pract 2023; 762-73.

5. Beasley R, Chang AB. Is tezepelumab the ubiquitous biologic for severe asthma? Lancet Respir Med 2023; 10.1016/S22132600(22)00530-6.

6. Beasley R, Hatter L. Over-the-Counter Dispensing: Widening access to ICS/formoterol reliever therapy. Am J Respir Crit Care Med 2023; 207: 377-9.

7. Beasley R, Kankaanranta H. Inhaled corticosteroids in asthma: when less is more. J Allergy Clin Immunol In Pract 2023; 11: 544-5.

8. Chen W, Reddel HK, FitzGerald JM, Beasley R, Janson C, Sadatsafavi M. Can we predict who will benefit most from biologics in severe asthma? A post-hoc analysis of two phase 3 trials. Respiratory Research 2023 (in press).

9. Denison H, Corbin M, Douwes J, Thompson S, Harwood M, Davis A, Fink JN, Barber PA, Gommans J, Cadilhac D, Levack W,

McNaughton H, Kim J, Feigin VL, Abernethy V, Girvan J, Wilson A, Ranta A. Ethnic differences in stroke outcomes in Aotearoa New Zealand: A national linkage study. Int J Stroke 2023; 17474930231164024.

10. Doppen M, Black M, Braithwaite I, Bong J, Eathorne E, Kirton L, Kung S, Walton M, Hills T, Weatherall M, Beasley R, Kearns C. Skin to deltoid muscle distance at three recommended injection sites in an obese population: an observational study. NZMJ 2023; 136: 67-76

11. Doppen M, Kearns C, Weatherall M, Kearns N, McIntyre P, Hills T, Beasley R. When should a longer needle be used for intramuscular injection in obese patients? A combined analysis of New Zealand data.Vaccine 2023; 41: 2690-5.

12. Doppen M, Mirjalili A, Harwood M, Eathorne A, Braithwaite I, Bong J, Kirton L, Semprini R, Weatherall M, Semprini A, Kearns C, Black M, Kung S, Walton M, Beasley R, Hills T. COVID-19 vaccination and the skin to deltoid muscle distance in adults with diabetes. Vaccine X 2023; 13: 100248.

13. Frei DR, Beasley R, Campbell D, Leslie K, Merry A, Moore M, Myles PS, Ruawai-Hamilton L, Short TG, Sibanda N, Young PJ. Perioperative oxygen administration in patients undergoing major non-cardiac surgery under general anaesthesia in Australia and New Zealand. Anaesth Intensive Care 2023; 310057X221131336.

14. Goligher EC, Lawler PR, Jensen TP, Talisa V, Berry LR, Lorenzi E, McVerry BJ, Chang C-CH, Leifer E, Bradbury C, Berger J, Hunt BJ, Castellucci LA, Kornblith LZ, Gordon AC, McArthur C, Webb S, Hochman J, Neal MD, Zarychanski R, Berry S, Angus DC, REMAP-CAP, ATTACC and ACTIV-4a Investigators. Heterogeneous Treatment Effects of Therapeutic-Dose Heparin in

Patients Hospitalized for COVID-19. JAMA 2023; doi:10.1001/jama.2023.3651

15. Hanly C, Leonardi M, Eathorne A, Armour M. The impact of diagnostic method on sense of control and powerlessness and social support in endometriosis patients-A retrospective cohort study. Acta Obstet Gynecol Scand 2023; doi.org/10.1111/aogs.14488

16. Higgins AM, Berry LR, Lorenzi E, Murthy S, McQuilten Z, Mouncey PR, Al-Beidh F, Annane D, Arabi YM, Beane A, van BentumPuijk W, Bhimani Z, Bonten MJM, Bradbury CA, Brunkhorst FM, Burrell A, Buzgau A, Buxton M, Charles WN, Cove M, Detry MA, Estcourt LJ, Fagbodun EO, Fitzgerald M, Girard TD, Goligher EC, Goossens H, Haniffa R, Hills T, Horvat CM, Huang DT, Ichihara N, Lamontagne F, Marshall JC, McAuley DF, McGlothlin A, McGuinness

SP, McVerry BJ, Neal MD, Nichol AD, Parke RL, Parker JC, Parry-Billings K, Peters SEC, Reyes

LF, Rowan KM, Saito H, Santos MS, Saunders CT, Serpa-Neto A, Seymour CW, Shankar-Hari

M, Stronach LM, Turgeon AF, Turner AM, van de Veerdonk FL, Zarychanski R, Green C, Lewis

RJ, Angus DC, McArthur CJ, Berry S, Derde LPG, Gordon AC, Webb SA, Lawler PR. Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial. JAMA 2023; 329: 39-51.

17. Hobman A, Levack WMM, Jones B, Ingham T, Fingleton J, Weatherall M, McNaughton A, McNaughton H. Prevention of Re-Hospitalization for Acute Exacerbations: Perspectives of People with Chronic Obstructive Pulmonary Disease: A Qualitative Study. Int J COPD 2023; 18: 207-18.

18. Kearns C, Houghton C, Dickinson E, Hatter L, Bruce P, Krishnamoorthy S, Weatherall M, Hills T, Doppen M, Ali Mirjalili S, Beasley R. What variables should inform needle length choice for deltoid intramuscular injection? A systematic review. BMJ Open 2023; 13: e063530.

19. Kim J, Cadilhac DA, Thompson S, Gommans J, Davis A, Barber PA, Fink J, Harwood M, Levack W, McNaughton H, Abernethy V, Girvan J, Feigin V, Denison H, Corbin M, Wilson A, Douwes J, Ranta A. Comparison of stroke care costs in urban and non-urban hospitals and its association with outcomes in New Zealand: A Nationwide Economic Evaluation. Stroke 2023; 54: 848-56.

20. Lee TY, Sadatsafavi M, Yadav CP, Price, DB, Beasley R, Janson C, Koh MS, Roy R, Chen W. Individualised risk prediction model for exacerbations in patients with severe asthma: protocol for a multicentre real-world risk modelling study. BMJ Open 2023; 13: e070459-e070459.

21. Levack WMM, Weatherall M, McNaughton HK, McNaughton AA, Hobman A, Jones B, Ingham TR, Fingleton J. Taking Charge After Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Randomized Controlled Feasibility Trial of a Psychologically Informed Self-Management Intervention. Int J COPD 2023; 18: 317-25.

22, Mak J, Eathorne A, Leonardi M, Espada M, Reid S, Zanardi JV, Uzuner C, Rocha R, Armour M, Condous G. External validation of the “2021 AAGL Endometriosis Classification”: a retrospective cohort study. J Minim Invasive Gynecol 2023; 10.1016/j.jmig.2022.12.012.

23. Mohan A, Lugogo NL, Hanania NA, Reddel HK, Akuthota P, O’Byrne PM, Guilbert T, Papi A, Price D, Jenkins CR, Kraft M, Bacharier LB, Boulet L-P, Yawn BP. Pleasants R, Lazarus SC, Beasley R, Gauvreau G, Elliot I, SchneiderFutschik EK, Yorgancioglu A, Martinez F, Moore W, Sumino K. Questions in Mild Asthma: an Official American Thoracic Society Research Statement. Am J Respir Crit Care Med 2023 (in press).

24. Munroe ES, Hyzy RC, Semler MW, Shankar-Hari M, Young PJ, Zampieri FG, Prescott HC. Evolving Management Practices for Early Sepsis-induced Hypoperfusion: A Narrative Review. Am J Respir Crit Care Med 2023; 10.1164/ rccm.202209-1831CI.

25. Murakami N, Hayden R, Hills T, AlSamkari H, Casey J, Del Sorbo L, Lawler PR, Sise ME, Leaf DE. Therapeutic advances in COVID-19. Nat Rev Nephrol 2023; 19: 38-52.

26. Perram J, Purtill D, Bajel A, Butler J, O’Brien T, Teh B, Gilroy N, Ho PJ, Doocey R, Hills T, Perera T, Douglas G, Ramachandran S, Chee L, Trotman J, Weinkove R, Keogh S, Fraser C, Cochrane T, Watson A, Diamond P, Latimer M, Irving I, Blyth E, Cheah C, Cole T, Milliken S, Yang H, Greenwood M, Bardy P, Kennedy G, Larsen S, Conyers R, Hamad N. ANZTCT Position Statement: COVID-19 management in patients with haematopoietic stem cell transplant and chimeric antigen receptor T cell. Int Med J 2023; 53: 119-25.

27. Rogliani P, Laitano R, Ora J, Beasley R, Calzetta L. Strength of association between comorbidities and asthma: a meta-analysis. Eur Respir Rev 2023; 32: 220202; DOI: 10.1183/16000617.0202-2022.

28. The REMAP CAP Investigators. Effect of Angiotensin Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Initiation on Organ Support Free Days in Patients

Hospitalized with COVID 19: A Randomized Clinical Trial. JAMA 2023 (In Press).

29. Saito H, on behalf of the Randomized, Embedded, Multifactorial Adaptive Platform trial for Community-Acquired Pneumonia (REMAPCAP) investigators. International platform trials: as diseases cross borders, so should trials. Lancet Infect Dis 2023 doi.org/10.1016/ S14733099(23)00193-7

2022

1. Adhikari NK, Pinto R, Day AG, Masse MH, Menard J, Sprague S, Annane D, Arabi YM, Battista MC, Cohen D, Cook DJ, Guyatt GH, Heyland DK, Kanji S, McGuinness SP, Parke RL, Kumar Tirupakuzhi Vijayaraghavan B, Charbonney E, Chasse M, Del Sorbo L, Kutsogiannis DJ, Lauzier F, Leblanc R, Maslove DM, Mehta S, Mekontso Dessap A, Mele TS, Rochwerg B, Rewa OG, Shahin J, Twardowski P, Young PJ, Lamontagne F. Lessening Organ dysfunction with VITamin C (LOVIT): statistical analysis plan. JMIR Res Protoc 2022; 11: e36261.

2. Agusti A, Rapsomaniki E, Beasley R, Hughes R, Müllerová H, Papi A, Pavord ID, van den Berge M, Faner R for the NOVELTY Study Investigators. Treatable traits in the NOVELTY study. Respirol 2022; 27: 929-40. doi: 10.1111/ resp.14325.

3. Ali H, Brooks C, Tzeng YC, Crane J, Beasley R, Gibson P, Pattemore P, Stanley T, Pearce N, Douwes J. Heart rate variability as a marker of autonomic nervous system activity in young people with eosinophilic and non-eosinophilic asthma. J Asthma 2022; 10.1080/02770903.2022.2070763.

4. Armour M, Avery J, Leonardi M, Van Niekerk L, Druitt ML, Parker MA, Girling JE, McKinnon B, Mikocka-Walus A, Ng CHM, O’Hara R, Ciccia D, Stanley K, Evans S. Lessons from implementing the Australian National Action Plan for Endometriosis. Reprod Fertil 2022; 3(3): C29-C39.

5. Armour M, Ciccia D, Stoikos C, Wardle J. Endometriosis and the workplace: Lessons from Australia’s response to COVID-19. Aust N Z J Obstet Gynaecol 2022; 62: 164-7.

6. Armour M, Parry K, Curry C, Ferfolja T, Parker MA, Farooqi T, MacMillan F, Smith CA, Holmes K. Evaluation of a web-based resource to improve menstrual health literacy and selfmanagement in young women. J Psychosom Res 2022; 162: 111038.

7. Armour M, Sinclair J, Cheng J, Davis P, Hameed A, Meegahapola H, Rajashekar K, Suresh S, Proudfoot A, Leonardi M. Endometriosis and cannabis consumption during the COVID-19 pandemic: an international cross-sectional survey. Cannabis Cannabinoid Res 2022; 7: 47381.

8. Baggott C, Hardy JK, Sparks J, Sabbagh D, Beasley R, Weatherall M, Fingleton J. Epinephrine (adrenaline) compared to selective beta-2-agonist in adults or children with acute asthma: a systematic review and meta-analysis. Thorax 2022; 77: 563-72.

9. Balthazar P, Klontzas ME, Heng LXX, Kearns C. Cowden Syndrome. Radiographics 2022; 42(2): E44-E45.

10. Barnett A, Beasley R, Buchan C, Chien J, Farah CS, King G, McDonald CF, Miller B, Munsif M, Psirides A, Reid L, Roberts M, Smallwood N, Smith S. Thoracic Society of Australia and New Zealand Position Statement on Acute Oxygen Use in Adults: ‘Swimming between the flags’. Respirology 2022; 27: 262-76.

11. Beasley R, Harrison T, Peterson S, Gustafson P, Hamblin A, Bengtsson T, Fagerås M. Evaluation of budesonide-formoterol for maintenance and reliever therapy among patients with poorly controlled asthma. A systematic review and meta-analysis. JAMA Network Open 2022; 5: e220615.

12. Bennett J, Moreland NJ, Williamson DA, Carapetis J, Crane J, Whitcombe AL, Jack S, Harwood M, Baker MG. Comparison of group A streptococcal titres in healthy children and those with pharyngitis and skin infections. J Infect 2022; 84: 24-30.

13. Bradbury CA, Lawler PR, Stanworth SJ, McVerry BJ, McQuilten Z, Higgins AM, Mouncey PR, Al-Beidh F, Rowan KM, Berry LR, Lorenzi E, Zarychanski R, Arabi YM, Annane D, Beane A, van Bentum-Puijk W, Bhimani Z, Bihari S, Bonten MJM, Brunkhorst FM, Buzgau A, Buxton M, Carrier M, Cheng AC, Cove M, Detry MA, Estcourt LJ, Fitzgerald M, Girard TD, Goligher EC, Goossens H, Haniffa R, Hills T, Huang DT, Horvat CM, Hunt BJ, Ichihara N, Lamontagne F, Leavis HL, Linstrum KM, Litton E, Marshall JC, McAuley DF, McGlothlin A, McGuinness SP, Middeldorp S, Montgomery SK, Morpeth SC, Murthy S, Neal MD, Nichol AD, Parke RL, Parker JC, Reyes L, Saito H, Santos MS, Saunders CT, Serpa-Neto A, Seymour CW, Shankar-Hari M, Singh V, Tolppa T, Turgeon AF, Turner AM, van de Veerdonk FL, Green C, Lewis RJ, Angus DC, McArthur CJ, Berry S, Derde LPG, Webb SA, Gordon AC. Effect of antiplatelet therapy on survival and organ support-free days in critically ill patients with covid-19: a randomized clinical trial. JAMA 2022; 327: 124759.

14. Brewer KM, Grey C, Paynter J, WinterSmith J, Hanchard S, Selak V, Ameratunga S, Harwood M. What are the gaps in cardiovascular risk assessment and management in primary care for Maori and Pacific people in Aotearoa New Zealand? Protocol for a systematic review. BMJ Open 2022: 12(6): e060145.

15. Bruce P, Ainscough K, Hatter L, Braithwaite I, Berry LR, Fitzgerald M, Hills T, Brickell K, Cosgrave D, Semprini A, Morpeth S, Berry S, Doran P, Young P, Beasley R, Nichol A. Correction: Prophylaxis in healthcare workers during a pandemic: a model for a multi-centre international randomised controlled trial using Bayesian analyses. Trials 2022; 23(1): 546.

16. Bryce A, Foley L, Phillipson J, Slow S, Storer M, Williman J, Beasley R, Bhally H, Chang CL, Dummer J, Epton M, Furniss M, Gracie K, Hancox RJ, Hills T, Hogg S, Hotu S, Kearns N, Morpeth S, Murdoch D, Raymond N, Ritchie S, Wong C, Maze MJ. Clinical features of patients hospitalised with COVID-19 from February to October 2020, during the early waves of the pandemic in New Zealand. NZ Med J 2022; 135: 120-30.

17. Carr AC, Spencer E, Mackle D, Hunt A, Judd H, Mehrtens J, Parker K, Stockwell Z, Gale C, Beaumont M, Kaur S, Bihari S, Young PJ. Corrigendum to “The effect of conservative oxygen therapy on systemic biomarkers of oxidative stress in critically ill patients” [Free Radical Biology and Medicine 160 (2020) 13-18]. Free Radic Biol Med 2022; 192: 50.

18. Chen H, Kunder R, Zou Y, Staton T, Zhu R, Galanter J, Gugelmann H, Owen R, Grimbaldeston MA, Chang JK, Durk MR, Eliahu A, Wilson MS, Choy DF, Wilson M, Black M, Doppen M, Kung S, Oldfield K, Sparks J, Beasley R, Braithwaite I. Effects of inhaled JAK inhibitor GDC-4379 on exhaled nitric oxide and peripheral biomarkers of inflammation. Pulm Pharmacol Ther 2022; 75: 102133.

19. Costa-Pinto R, Yong ZT, Yanase F, Young C, Brown A, Udy A, Young PJ, Eastwood G, Bellomo R. A pilot, feasibility, randomised controlled trial of midodrine as adjunctive vasopressor for low-dose vasopressordependent hypotension in intensive care patients: The MAVERIC study. J Crit Care 2022; 67: 166-71.

20. Couillard S, Do WIH, Beasley R, Hinks TSC, Pavord ID. Predicting the benefits of type-2 targeted anti-inflammatory treatment with the prototype Oxford Asthma Attack Risk Scale (ORACLE). ERJ Open Res 2022; 8: 10.1183/23120541.00570-2021.

21. Couillard S, Steyerberg E, Beasley R, Pavord I. Blood eosinophils, fractional exhaled nitric oxide and the risk of asthma attacks in randomised controlled trials: protocol for a systemic review and control arm patient-level meta-analysis for clinical prediction modelling. BMJ Open 2022; 12: e058215.

22. Daley-Yates P, Keppler B, Baines A, Bardsley G, Fingleton J. Metabolomic changes related to airway inflammation, asthma pathogenesis and systemic activity following inhaled fluticasone furoate/vilanterol: a randomized controlled trial. Respir Res 2022; 23(1): 258.

23. Darvall JN, Bellomo R, Bailey M, Young PJ, Pilcher D. Frailty in the ICU: information is the required first step. Intensive Care Med 2022; 48: 1260-1.

24. Darvall JN, Bellomo R, Bailey M, Young PJ, Rockwood K, Pilcher D. Impact of frailty on persistent critical illness: a population-based cohort study. Intensive Care Med 2022; 48: 34351.

25. Doppen M, Kung S, Maijers I, John M, Dunphy H, Townsley H, Eathorne A, Semprini A, Braithwaite I. Cannabis in palliative care: a systematic review of current evidence. J Pain Symptom Manage 2022; 64: e260-e284.

26. Finfer S, Micallef S, Hammond N, Navarra L, Bellomo R, Billot L, Delaney A, Gallagher M, Gattas D, Li Q, Mackle D, Mysore J, Saxena M, Taylor C, Young P, Myburgh J. Balanced multielectrolyte solution versus saline in critically ill adults. N Engl J Med 2022; 386(9): 815-26.

27. Foster J, Beasley R, Braithwaite I, Harrison T, Holliday M, Pavord I, Reddel H. Perspectives of mild asthma patients on maintenance versus as-needed preventer treatment regimens: a qualitative study. BMJ Open 2022; 12: e048537.

28. Fujii T, Salanti G, Belletti A, Bellomo R, Carr A, Furukawa TA, Luethi N, Luo Y, Putzu A, Sartini C, Tsujimoto Y, Udy AA, Yanase F, Young PJ. Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis. Intensive Care Med 2022; 48: 1624.

29. Garg T, Kearns C, Kim E, Ballard DH. Multiple Systemic Arterial aneurysms in Kawasaki Disease. Radiographics 2022; 42(3): E88-E89.

30. Golam SM, Janson C, Beasley R, FitzGerald JM, Harrison T, Chipps B, Hughes R, Mullerova H, Olaguibel JM, Rapsomaniki E, Reddel HK, Sadatsafavi M. The burden of mild asthma: Clinical burden and healthcare resource utilisation in the NOVELTY study. Respir Med 2022; 200: 106863.

31. Graca S, Betts D, Roberts K, Smith CA, Armour M. The changing clinical landscape in acupuncture for women’s health: a crosssectional online survey in New Zealand and Australia. BMC Complement Med Ther 2022; 22: 94.

32. Granholm A, Alhazzani W, Derde LPG, Angus DC, Zampieri FG, Hammond NE, Sweeney RM, Myatra SN, Azoulay E, Rowan K, Young PJ, Perner A, Moller MH. Randomised clinical trials in critical care: past, present and future. Intensive Care Med 2022; 48: 164-78.

33. Hammond NE, Zampieri FG, Di Tanna GL, Garside T, Adigbli D, Cavalcanti AB, Machado FR, Micallef S, Myburgh J, Ramanan M, Rice TW, Semler MW, Young PJ, Venkatesh B, Finfer S, Delany A. Balanced crytalloids versus saline in critically ill adults — a systematic review with meta-analysis. NEJM Evid 2022; 1: doi: 10.1056/ EVIDoa2100010.

34. Harper J, Kearns N, Bird G, McLachlan R, Eathorne A, Weatherall M, Beasley R. Audit of oxygen administration to achieve a target oxygen saturation range in acutely unwell medical patients. Postgrad Med J 2022; 98: 4615.

35. Harwood MLN, Ranta A, Thompson SG, Ranta SM, Brewer K, Gommans JH, Davis A, Barber PA, Corbin M, Fink JN, McNaughton HK, Abernethy G, Girvan J, Feigin V, Wilson A, Cadilhac D, Denison H, Kim J, Levack W, Douwes J. Barriers to optimal stroke service care and solutions: a qualitative study engaging people with stroke and their whānau . NZMJ 2022; 135(1556): 81-93.

36. Harwood M, Te Paa S, Kearns N, Luki H, Anderson A, Semprini A, Beasley R. An audit of a marae-based health centre management of COVID-19 community cases in South Auckland. NZ Med J 2022; 135(1549): 120-128.

37. Hatter L, Bruce P, Beasley R. A breath of fresh AIR: reducing the carbon footprint in asthma. J Med Econ 2022; 25: 700-2.

38. Hatter L, Houghton C, Bruce P, Holliday M, Eathorne A, Pavord I, Reddel HK, Hancox RJ, Braithwaite I, Oldfield K, Papi A, Weatherall M, Beasley R. Asthma control with ICS-formoterol reliever versus maintenance ICS and SABA reliever therapy: a post hoc analysis of two randomised controlled trials. BMJ Open Respir Res 2022; 9: e001271.

39. Hays LMC, Black M, Prunty MP, Murthy S, van de Veerdonk F, Annane D, Binnie A, Burrell A, Derde LPG, Gordon AC, Green C, Guillon A, Keat K, Lawler PR, Lye DC, Mayr FB, McArthur C, McAuley D, McVerry BJ, Morpeth S, Phua J, Pletz M, Reyes L, Saxena M, Seppelt I, ShankarHari M, Sligl WI, Turner AM, Uyeki TM, VazquezGrande G, Webb SA, Ainscough K, Haren AP, Hills T, Nichol A. Could treatment with immunomodulatory agents targeting IL-1, IL-6, or JAK signalling improve outcomes in patients with severe influenza pneumonia? A systematic and narrative review. HRB Open Research 2022, 5:77 doi: hrbopenresearch.org/articles/5-77/v1.

40. Hays LMC, Udy A, Adamides AA, Anstey JR, Bailey M, Bellapart J, Byrne K, Cheng A, Jamie Cooper D, Drummond KJ, Haenggi M, Jakob SM, Higgins AM, Lewis PM, Hunn MK, McNamara R, Menon DK, Murray L, Reddi B, Trapani T, Vallance S, Young PJ, Diaz-Arrastia R, Shutter L, Murray PT, Curley GF, Nichol A. Effects of brain tissue oxygen (PbtO2) guided management on patient outcomes following severe traumatic brain injury: A systematic review and meta-analysis. J Clin Neurosci 2022; 99: 349-58.

41. Hernandez-Mitre MP, Tong SYC, Denholm JT, Dore GJ, Bowen AC, Lewin SR, Venkatesh B, Hills TE, McQuilten Z, Paterson DL, Morpeth SC, Roberts JA. Nafamostat mesylate for treatment of COVID-19 in hospitalised patients: a structured, narrative review. Clin Pharmacokinet 2022; 61: 1331-43.

42. Hills T, Beasley R. Letter from New Zealand. Respirology 2022; 27: 994-5.

43. Hills T, Paterson A, Woodward R, Middleton F, Carlton LH, McGregor R, Barfoot S, Ramiah C, Whitcombe AL, Zimbron VM, Mahuika D, Brown J, Palmer-Neels K, Manning B, Jani D, Reeves B, Whitta GT, Morpeth S, Beasley R, Weatherall M, Jordan A, McIntyre P, Moreland NJ, Mirjalili SA. The effect of needle length and skin to deltoid muscle distance in adults receiving an mRNA COVID-19 vaccine. Vaccine 2022; 40(33): 4827-34.

44. Hills T, Sharpe C, Wong T, Cutfield T, Lee A, McBride S, Rogers M, Ching Soh M, Taylor A, Taylor S, Thomas M. Fetal loss and preterm birth caused by intraamniotic Haemophilus influenzae infection, New Zealand. Emerg Infect Dis 2022; 28: 1747-54.

45. Hodgson CL, Bailey M, Bellomo R, Brickell K, Broadley T, Buhr H, Gabbe BJ, Gould DW, Harrold M, Higgins AM, Hurford S, Iwashyna TJ, Serpa Neto A, Nichol AD, Presneill JJ, Schaller SJ, Sivasuthan J, Tipping CJ, Webb S, Young PJ. Early active mobilization during mechanical ventilation in the ICU. N Engl J Med 2022; 387(19): 1747-58.

46. Hodgson CL, Higgins AM, Bailey MJ, Anderson S, Bernard S, Fulcher BJ, Koe D, Linke NJ, Board JV, Brodie D, Buhr H, Burrell AJC, Cooper DJ, Fan E, Fraser JF, Gattas DJ, Hopper IK, Huckson S, Litton E, McGuinness SP, Nair P, Orford N, Parke RL, Pellegrino VA, Pilcher DV, Sheldrake J, Reddi BAJ, Stub D, Trapani TV, Udy AA, Serpa Neto A. Incidence of death or disability at 6 months after extracorporeal membrane oxygenation in Australia: a prospective, multicentre, registry-embedded cohort study. Lancet Respir Med 2022; 10(11): 1038-48.

47. Kearns C, Arnold D, Caswell-Smith P. Response to: ‘Use of computed tomography left atrial appendage as an alternative to trans-oesophageal echocardiography during the COVID-19 pandemic’. J Med Imaging Radiat Oncol 2022; 66: 964-5.

48. Kearns C, Eathorne A, Kearns N, Anderson A, Hatter L, Semprini A, Beasley R. How best to share research with study participants? A randomised crossover trial comparing a comic, lay summary, and scientific abstract. J Vis Commun Med 2022; 45: 172-81.

49. Kearns C, Murton S, Oldfield K, Anderson A, Eathorne A, Beasley R, Nacey J, Jaye C. Estimating the prevalence of drawing in clinical practice among kiwi doctors. J Vis Commun Med 2022; 45: 234-41.

50. Kearns N, Bruce P, Williams M, Doppen M, Black M, Weatherall M, Beasley R. Repeated dose budesonide/formoterol compared to salbutamol in adult asthma: A randomised cross-over trial. Eur Respir J 2022; 10.1183/13993003.02309-2021.

51. Kearns N, Williams M, Bruce P, Black M, Kearns C, Sparks J, Braithwaite I, Weatherall M, Beasley R. Single dose of budesonide/ formoterol turbuhaler compared to salbutamol pMDI for speed of bronchodilator onset in asthma: a randomised cross-over trial. Thorax 2022; 10.1136/thorax-2022-219052.

52. Klontzas ME, Kearns C, Sheikhbahaei S, Cornejo P. Anti-NMDA-Receptor Encephalitis. Radiographics 2022; 42(7): E199-E200.

53. Lamontagne F, Masse MH, Menard J, Sprague S, Pinto R, Heyland DK, Cook DJ, Battista MC, Day AG, Guyatt GH, Kanji S, Parke R, McGuinness SP, Tirupakuzhi Vijayaraghavan BK, Annane D, Cohen D, Arabi YM, Bolduc B, Marinoff N, Rochwerg B, Millen T, Meade MO, Hand L, Watpool I, Porteous R, Young PJ, D’Aragon F, Belley-Cote EP, Carbonneau E, Clarke F, Maslove DM, Hunt M, Chasse M, Lebrasseur M, Lauzier F, Mehta S, Quiroz-Martinez H, Rewa OG, Charbonney E, Seely AJE, Kutsogiannis DJ, LeBlanc R, Mekontso-Dessap A, Mele TS, Turgeon AF, Wood G, Kohli SS, Shahin J, Twardowski P, Adhikari NKJ. Intravenous Vitamin C in adults with sepsis in the Intensive Care Unit. N Engl J Med 2022; 386: 2387-98.

54. Malik A, Sinclair J, Ng CHM, Smith CA, Abbott J, Armour M. Allied health and complementary therapy usage in Australian women with chronic pelvic pain: a crosssectional study. BMC Womens Health 2022; 22: 37.

55. McGuinness S, Charlewood R, Gilder E, Parke R, Hayes K, Morley S, Al-Ibousi A, Deans R, Howe B, Johnson L, Marks DC, Reade MC. A pilot randomized clinical trial of cryopreserved versus liquid-stored platelet transfusion for bleeding in cardiac surgery: The cryopreserved versus liquid platelet-New Zealand pilot trial. Vox Sang 2022; 117: 337-45.

56. McNaughton H, Gommans J, McPherson K, Harwood M, Fu V. A cohesive, person-centric evidence-based model for successful rehabilitation after stroke and other disabling conditions. Clin Rehab 2022 doi: 10.1177/02692155221145433.

57. Mistry R, Frei DR. Reply to comment on ‘A survey of self-reported use of cricoid pressure amongst Australian and New Zealand anaesthetists; Attitudes and practice’. Anaesth Intensive Care 2022; 50: 333-4.

58. Murphy AN, Kearns C. Gastrointestinal Stromal Tumors and their Appearance in Patients with Neurofibromatosis Type 1. Radiographics 2022; 42(4): E111-E112.

59. Myburgh JA, Seppelt IM, Goodman F, Billot L, Correa M, Davis JS, Gordon AC, Hammond NE, Iredell J, Li Q, Micallef S, Miller J, Mysore J, Taylor C, Young PJ, Cuthbertson BH, Finfer SR. Effect of selective decontamination of the digestive tract on hospital mortality in critically ill patients receiving mechanical ventilation: a randomized clinical trial. JAMA 2022; 328(19): 1911-21.

60. Oldfield K, Eathorne A, TewhaitiSmith J, Beasley R, Semprini A, Braithwaite I. Experiences, patient interactions and knowledge regarding the use of cannabis as a medicine in a cohort of New Zealand doctors in an oncology setting. Postgrad Med J 2022; 98: 35-42.

61. Papi A, Chipps BE, Beasley R, Panettieri RA, Jr., Israel E, Cooper M, Dunsire L, JeynesEllis A, Johnsson E, Rees R, Cappelletti C, Albers FC. Albuterol-budesonide fixed-dose combination rescue inhaler for asthma. N Engl J Med 2022; 386(22): 2071-83.

62. Parke RL, Cavadino A, McGuinness SP. Transfusion practice in patients undergoing cardiac surgery in New Zealand-impact of the TRICS III study (the TRICS TRIPS study). NZ Med J 2022; 135(1562): 34-47.

63. Poole AP, Finnis ME, Anstey J, Bellomo R, Bihari S, Birardar V, Doherty S, Eastwood G, Finfer S, French CJ, Heller S, Horowitz M, Kar P, Kruger PS, Maiden MJ, Martensson J, McArthur CJ, McGuinness SP, Secombe PJ, Tobin AE, Udy AA, Young PJ, Deane AM. The Effect of a liberal approach to glucose control in critically ill patients with Type 2 diabetes: a multicenter, parallel-group, open-label, randomized clinical trial. Am J Respir Crit Care Med 2022; 206: 87482. doi: 10.1164/rccm.202202-0329OC.

64. Rao VS, Cowan S, Armour M, Smith CA, Cheema BS, Moran L, Lim S, Gupta S, Manincor M, Sreedhar V, Ee C. A Global Survey of Ethnic Indian Women Living with Polycystic Ovary Syndrome: Co-Morbidities, Concerns, Diagnosis Experiences, Quality of Life, and Use of Treatment Methods. Int J Environ Res Public Health 2022; 19(23): doi: 10.3390/ ijerph192315850.

65. Reade MC, Marks DC, Howe B, McGuinness S, Parke R, Navarra L, Charlewood R, Johnson L, McQuilten Z, on behalf of the CLIPII and CLIPNZ-II investigators. Cryopreserved platelets compared with liquid-stored platelets for the treatment of surgical bleeding: protocol for two multicentre randomised controlled blinded non-inferiority trials (the CLIP-II and CLIPNZ-II trials). BMJ Open 2022; 12: e068933.

66. Reid AL, Bailey M, Harwood M, Moore JE, Young PJ. Outcomes for Maori and European patients admitted to New Zealand intensive care units between 2009 and 2018. NZ Med J 2022; 135(1550): 26-46.

67. Robba C, Badenes R, Battaglini D, Ball L, Brunetti I, Jakobsen JC, Lilja G, Friberg H, Wendel-Garcia PD, Young PJ, Eastwood G, Chew MS, Unden J, Thomas M, Joannidis M, Nichol A,

Lundin A, Hollenberg J, Hammond N, Saxena M, Annborn M, Solar M, Taccone FS, Dankiewicz J, Nielsen N, Pelosi P. Ventilatory settings in the initial 72 h and their association with outcome in out-of-hospital cardiac arrest patients: a preplanned secondary analysis of the targeted hypothermia versus targeted normothermia after out-of-hospital cardiac arrest (TTM2) trial. Intensive Care Med 2022; 48(8): 1024-38.

68. Robba C, Badenes R, Battaglini D, Ball L, Sanfilippo F, Brunetti I, Jakobsen JC, Lilja G, Friberg H, Wendel-Garcia PD, Young PJ, Eastwood G, Chew MS, Unden J, Thomas M, Joannidis M, Nichol A, Lundin A, Hollenberg J, Hammond N, Saxena M, Martin A, Solar M, Taccone FS, Dankiewicz J, Nielsen N, Grejs AM, Ebner F, Pelosi P. Oxygen targets and 6-month outcome after out of hospital cardiac arrest: a pre-planned sub-analysis of the targeted hypothermia versus targeted normothermia after Out-of-Hospital Cardiac Arrest (TTM2) trial. Crit Care 2022; 26(1): 323.

69. Ross J, Ramsay DP, Sutton-Smith LJ, Willink RD, Moore JE. Residual neuromuscular blockade in the ICU: a prospective observational study and national survey. Anaesthesia 2022; 77(9): 991-8.

70. Sabag A, Barr L, Armour M, Armstrong A, Baker CJ, Twigg SM, Chang D, Hackett DA, Keating SE, George J, Johnson NA. The effect of high-intensity interval training vs moderateintensity continuous training on liver fat: a systematic review and meta-analysis. J Clin Endocrinol Metab 2022; 107: 862-81.

71. Schlapbach LJ, Gibbons KS, Horton SB, Johnson K, Long DA, Buckley DHF, Erickson S, Festa M, d’Udekem Y, Alphonso N, Winlaw DS, Delzoppo C, van Loon K, Jones M, Young PJ, Butt W, Schibler A. Effect of nitric oxide via cardiopulmonary bypass on ventilator-free days in young children undergoing congenital heart disease surgery: The NITRIC Randomized Clinical Trial. JAMA 2022; 328(1): 38-47.

72. Sheikhbahaei S, Kearns C, Jean J, Garg T. Malignant paraganglioma with brown adipose tissue activation. Radiographics 2022; 42(1): E14-E15.

73. Shortt N, Martin A, Kerse K, Shortt G, Vakalalabure I, Barker L, Singer J, Black B, Liu A, Eathorne A, Weatherall M, Rademaker M, Armour M, Beasley R, Semprini A. Efficacy of a 3% Kanuka oil cream for the treatment of moderate-to-severe eczema: A single blind randomised vehicle-controlled trial. eClinicalMedicine 2022; 51: 101561.

74. Simpson RFG, Dankiewicz J, Karamasis GV, Pelosi P, Haenggi M, Young PJ, Jakobsen JC, Bannard-Smith J, Wendel-Garcia PD, Taccone FS, Nordberg P, Wise MP, Grejs AM, Lilja G, Olsen RB, Cariou A, Lascarrou JB, Saxena M, Hovdenes J, Thomas M, Friberg H, Davies JR, Nielsen N, Keeble TR. Speed of cooling after cardiac arrest in relation to the intervention effect: a substudy from the TTM2-trial. Crit Care 2022; 26(1): 356.

75. Sinclair J, Armour S, Akowuah JA, Proudfoot A, Armour M. “Should I Inhale?” Perceptions, barriers, and drivers for medicinal cannabis use amongst australian women with primary dysmenorrhoea: a qualitative study. Int J Environ Res Public Health 2022; 19: 10.3390/ ijerph19031536.

76. Sinclair J, Toufaili Y, Gock S, Pegorer AG, Wattle J, Franke M, Alzwayid M, Abbott J, Pate DW, Sarris J, Armour M. Cannabis use for endometriosis: clinical and legal challenges in Australia and New Zealand. Cannabis Cannabinoid Res 2022; 7(4): 464-72.

77. Slater A, Beca J, Croston E, McEniery J, Millar J, Norton L, Numa A, Schell D, Secombe P, Straney L, Young P, Yung M, Gabbe B, Shann F. Association between centralization and outcome for children admitted to Intensive Care in Australia and New Zealand: a populationbased cohort study. Pediatr Crit Care Med 2022; 23: 919-28.

78. Sweet DE, Wheeler CA, Kearns C, Marquis KM. Pulmonary light-chain deposition disease. Radiographics 2022; 42(5): E145-E146.

79. Tan E, Hoare K, Riley J, Fernando K, Haskell L, McKinlay CJ, Dalziel SR, Braithwaite I. Panic or peace — prioritising infant welfare when medicating feverish infants: a grounded theory study of adherence in a paediatric clinical trial. BMC Pediatr 2022; 22: 195.

80. Te Ao B, Harwood M, Fu V, Weatherall M, McPherson K, Taylor WJ, McRae A, Thomson T, Gommans J, Green G, Ranta A, Hanger C, Riley J, McNaughton H. Economic analysis of the ‘Take Charge’ intervention for people following stroke: Results from a randomised trial. Clin Rehabil 2022; 36: 240-50.

81. Tewhaiti-Smith J, Semprini A, Bush D, Anderson A, Eathorne A, Johnson N, Girling J, East M, Marriott J, Armour M. An Aotearoa New Zealand survey of the impact and diagnostic delay for endometriosis and chronic pelvic pain. Sci Rep 2022; 12: 4425.

82. Thompson KJ, Young PJ, Venkatesh B, Cohen J, Finfer SR, Grattan S, Hammond NE, Jan S, Li Q, Di Tanna GL, McArthur C, Myburgh J,

Rajbhandari D, Taylor CB. Long-term costs and cost-effectiveness of adjunctive corticosteroids for patients with septic shock in New Zealand. Aust Crit Care 2022; 35: 241-50.

83. Thompson SG, Barber PA, Gommans

JH, Cadilhac DA, Davis A, Fink JN, Harwood M, Levack W, McNaughton H, Feigin VL, Abernethy V, Girvan J, Denison H, Corbin M, Wilson A, Douwes J, Ranta A. The impact of ethnicity on stroke care access and patient outcomes: a New Zealand nationwide observational study. Lancet Reg Health West Pac 2022; 20: 100358.

84. Thompson SG, Barber PA, Gommans

JH, Cadilhac DA, Davis A, Fink JN, Harwood M, Levack W, McNaughton HK, Feigin VL, Abernethy V, Girvan J, Kim J, Denison H, Corbin M, Wilson A, Douwes J, Ranta A. Geographic disparities in stroke outcomes and service access: a prospective observational study. Neurology 2022; 99: e414-26.

85. Thompson S, Levack W, Douwes J, Girvan J, Abernethy G, Barber PA, Fink J, Gommans J, Davis A, Harwood M, Cadilhac DA, McNaughton H, Feigin V, Wilson A, Denison H, Corbin M, Kim J, Ranta A. Patient, carer and health worker perspectives of stroke care in New Zealand: a mixed methods survey. Disabil Rehabil 2022: 1-7.

86. Turner VL, Kearns C, Wattamwar K, McKenney AS. Klippel-Trenaunay Syndrome. Radiographics 2022; 42(6): E167-E168.

87. van Diepen S, Coulson T, Wang X, Opgenorth D, Zuege DJ, Harris J, Agyemang M, Niven DJ, Bellomo R, Wright SE, Young PJ, Bagshaw SM. Efficacy and safety of proton pump inhibitors versus histamine-2 receptor blockers in the cardiac surgical population: insights from the PEPTIC trial. Eur J Cardiothorac Surg 2022; 62: 10.1093/ejcts/ezac124.

88. Wetterslev M, Moller MH, Granholm A, Hassager C, Haase N, Naz Aslam T, Shen J, Young PJ, Aneman A, Hastbacka J, Siegemund M, Cronhjort M, Lindqvist E, Myatra SN, Kalvit K, Arabi YM, Szczeklik W, Sigurdsson MI, Balik M, Keus F, Perner A. Management of acute atrial fibrillation in the intensive care unit: an international survey. Acta Anaesthesiol Scand 2022; 66: 375-85.

89. Writing Committee for the REMAP-CAP Investigators. Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial. JAMA 2023; 329(1): 39-51.

90. Young PJ, Arabi YM, Bagshaw SM, Bellomo R, Fujii T, Haniffa T, Hodgson CL, Tirupakuzhi Vijayaraghavan BK, Litton E, Mackle D, Nichol A, Kasza J, The Mega-ROX Management Committee, The Australian and New Zealand Intensive Care Society Clinical Trials Group, The Crit Care Asia and Africa Network, The Irish Critical Care Clinical Trials Group, The Alberta Health Services Critical Care Strategic Clinical Network. Protocol and statistical analysis plan for the mega randomised registry trial research program comparing conservative versus liberal oxygenation targets in adults receiving unplanned invasive mechanical ventilation in the ICU (Mega-ROX). Crit Care Resusc 2022; 24(2): 137-49.

91. Young PJ. Recent data and the French guidelines for choice of intravenous fluids for vascular filling. Anaesth Crit Care Pain Med 2022: 41(3): 101100.

92. Young PJ, Hodgson CL, Rasmussen BS. Oxygen targets. Intensive Care Med 2022; 48: 732-5. 10.1007/s00134-022-06714-0.

93. Young PJ, Lamontagne F, Fujii T. Vitamin C in sepsis. Intensive Care Med 2022; 48: 1621-4.

94. Young PJ, Mackle D, Hodgson C, Bellomo R, Bailey M, Beasley R, Deane AM, Eastwood G, Finfer S, Freebairn R, King V, Linke N, Litton E, McArthur C, McGuinness S, Panwar R. Conservative or liberal oxygen therapy for mechanically ventilated adults with acute brain pathologies: A post-hoc subgroup analysis. J Crit Care 2022; 71: 154079.

95. Zampieri FG, da Costa BR, Vaara ST, Lamontagne F, Rochwerg B, Nichol AD, McGuinness S, McAuley DF, Ostermann M, Wald R, Bagshaw SM. A Bayesian reanalysis of the Standard versus Accelerated Initiation of RenalReplacement Therapy in Acute Kidney Injury (STARRT-AKI) trial. Crit Care 2022; 26(1): 255.

2021

1. Aryal D, Beane A, Dondorp AM, Green C, Haniffa R, Hashmi M, Jayakumar D, Marshall JC, McArthur CJ, Murthy S, Webb SA, Acharya SP, Ishani PGP, Jawad I, Khanal S, Koirala K, Luitel S, Pabasara U, Paneru HR, Kumar A, Patel SS, Ramakrishnan N, Salahuddin N, Shaikh M, Tolppa T, Udayanga I, Umrani Z. Operationalisation of the Randomized Embedded Multifactorial Adaptive Platform for COVID-19 trials in a low and lower-middle income critical care learning health system. Wellcome Open Res 2021; 6: 14.

2. ATTACC Investigators; ACTIV-4a Investigators; REMAP-CAP Investigators. Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19. NEJM/ New England Journal of Medicine. 2021 Aug 4. doi: 10.1056/NEJMoa2105911.

3. Axfors C, Schmitt AM, Janiaud P, Van’t Hooft J, Abd-Elsalam S, Abdo EF, Abella BS, Akram J, Amaravadi RK, Angus DC, Arabi YM, Azhar S, Baden LR, Baker AW, Belkhir L, Benfield T, Berrevoets MAH, Chen CP, Chen TC, Cheng SH, Cheng CY, Chung WS, Cohen YZ, Cowan LN, Dalgard O, de Almeida EVFF, de Lacerda MVG, de Melo GC, Derde L, Dubee V, Elfakir A, Gordon AC, Hernandez-Cardenas CM, Hills T, Hoepelman AIM, Huang YW, Igau B, Jin R, Jurado-Camacho F, Khan KS, Kremsner PG, Kreuels B, Kuo CY, Le T, Lin YC, Lin WP, Lin TH, Lyngbakken MN, McArthur C, McVerry BJ, Meza-Meneses P, Monteiro WM, Morpeth SC, Mourad A, Mulligan MJ, Murthy S, Naggie S, Narayanasamy S, Nichol A, Novack LA, O’Brien SM, Okeke NL, Perez L, Perez-Padilla R, Perrin L, Remigio-Luna A, Rivera-Martinez NE, Rockhold FW, Rodriguez-Llamazares S, Rolfe R, Rosa R, Rosjo H, Sampaio VS, Seto TB, Shahzad M, Soliman S, Stout JE, Thirion-Romero I, Troxel AB, Tseng TY, Turner NA, Ulrich RJ, Walsh SR, Webb SA, Weehuizen JM, Velinova M, Wong HL, Wrenn R, Zampieri FG, Zhong W, Moher D, Goodman SN, Ioannidis JPA, Hemkens LG. Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials. Nat Commun 2021; 12: 2349.

4. Beasley R, Bruce P, Hatter L, Braithwaite I, Semprini A, Kearns C, Weatherall M, Pavord ID. A proposed revision of the stepwise treatment algorithm in asthma. Am J Respir Crit Care Med 2021; 10.1164/rccm.2021010224LE.

5. Beasley R, Hills T, Kearns N. Asthma and COVID-19: preconceptions about predisposition. Am J Respir Crit Care Med 2021; 203: 799-801.

6. Beasley R, Weatherall M. The vexed problem of corticosteroid toxicity in asthma: time for standardized assessment. J Allergy Clin Immunol Pract 2021; 9: 373-4.

7. Braithwaite IE, Cai F, Tom JA, Galanter JM, Owen RP, Zhu R, Williams M, McGregor AG, Eliahu A, Durk MR, Dengler HS, Zak M, Kenny JR, Wilson ME, Beasley R, Chen H. Inhaled JAK inhibitor GDC-0214 reduces exhaled nitric oxide in patients with mild asthma: a randomized, controlled, proof-of-activity trial. J Allergy Clin Immunol 2021; 10.1016/j.jaci.2021.02.042.

8. Brown S, Ball E, Lee YCG, Beasley R, Simpson G. Management of primary spontaneous pneumothorax: less is more. Lancet 2021; 396(10267): 1973.

9. Chang AB, Beasley R. More options for managing severe asthma in adults. Lancet Respir Med 2021; 9: 3-5.

10. Duffy E, Arroll N, Beasley R, Hills T. Regulatory action to protect access to hydroxychloroquine for approved rheumatologic indications during COVID-19 in New Zealand. Arthritis Rheumatol 2021; 10.1002/ art.41643.

11. Gordon AC, Mouncey PR, Al-Beidh F, Rowan KM, Nichol AD, Arabi YM, Annane D, Beane A, van Bentum-Puijk W, Berry LR, Bhimani Z, Bonten MJM, Bradbury CA, Brunkhorst

FM, Buzgau A, Cheng AC, Detry MA, Duffy EJ, Estcourt LJ, Fitzgerald M, Goossens H, Haniffa

R, Higgins AM, Hills TE, Horvat CM, Lamontagne

F, Lawler PR, Leavis HL, Linstrum KM, Litton

E, Lorenzi E, Marshall JC, Mayr FB, McAuley

DF, McGlothlin A, McGuinness SP, McVerry BJ, Montgomery SK, Morpeth SC, Murthy S, Orr K, Parke RL, Parker JC, Patanwala AE, Pettila V, Rademaker E, Santos MS, Saunders CT, Seymour CW, Shankar-Hari M, Sligl WI, Turgeon AF, Turner AM, van de Veerdonk FL, Zarychanski R, Green C, Lewis RJ, Angus DC, McArthur CJ, Berry S, Webb SA, Derde LPG. Interleukin-6 receptor antagonists in critically ill patients with Covid-19. N Engl J Med 2021; 384: 1491-502.

12. Hancox RJ, Jones S, Baggott C, Chen D, Corna N, Davies C, Fingleton J, Hardy J, Hussain S, Poot B, Reid J, Travers J, Turner J, Young R. New Zealand COPD Guidelines: Quick Reference Guide. NZ Med J 2021; 134(1530): www.nzma.org. nz/journal.

13. Harper JC, Kearns NA, Maijers I, Bird GE, Braithwaite I, Shortt NP, Eathorne A, Weatherall M, Beasley R. Closed-loop oxygen control using a novel nasal high-flow device: a randomized crossover trial. Respir Care 2021; 66: 416-24.

14. Hatter L, Bruce P, Braithwaite I, Holliday M, Fingleton J, Weatherall M, Beasley R. ICS-formoterol reliever vs ICS and SABA reliever in asthma: a systematic review and meta-analysis. Eur Respir J Open Res 2021; 7: doi: 10.1183/23120541.00701-2020.

15. Karlsson N, Atkinson MJ, Müllervoa H, Alacqua M, Keen C, Hughes R, Janson C, Make B, Price D, Reddel HK for the NOVELTY study investigators. Validation of a diagnosisagnostic symptom questionnaire for asthma and/or COPD. ERJ Open Res 2021; 7: doi: 10.1183/23120541.00828-2020.

16. Kearns C. Contemporary evidence of art’s relevance to the modern plastic surgeon. J Plast Reconstr Aesthet Surg 2021: 74(4): 890930.

17. Kearns C, Kearns N, Braithwaite I, Shortt N, Eathorne A, Semprini A, Beasley R. Using comics and curiosity to drive pandemic research on a national scale. J Vis Commun Med 2021: 44(1): 12-22.

18. Kearns N, Shortt N, Kearns C, Eathorne A, Holliday M, Mackle D, Martindale J, Semprini A, Weatherall M, Beasley R, Braithwaite I. How big is your bubble? Characteristics of selfisolating household units (‘bubbles’) during the COVID-19 Alert Level 4 period in New Zealand: a cross-sectional survey. BMJ Open 2021: 11(1): e042464.

19. Kung S, Doppen M, Black M, Braithwaite I, Kearns C, Weatherall M, Beasley R, Kearns N. Underestimation of COVID-19 mortality during the pandemic. ERJ Open Res 2021: 7(1).

20. Kung S, Doppen M, Black M, Hills T, Kearns N. Reduced mortality in New Zealand during the COVID-19 pandemic. Lancet 2021; 397: 25.

21. McNaughton H, Weatherall M, McPherson K, Fu V, Taylor WJ, McRae A, Thomson T, Gommans J, Green G, Harwood M, Ranta A, Hanger C, Riley J. The effect of the Take Charge intervention on mood, motivation, activation and risk factor management: Analysis of secondary data from the Taking Charge after Stroke (TaCAS) trial. Clin Rehabil 2021: 269215521993648.

22. Mistry R, Frei DR, Badenhorst C, Broadbent J. A survey of self-reported use of cricoid pressure amongst Australian and New Zealand anaesthetists: Attitudes and practice. Anaesth Intensive Care 2021; 49: 62-9.

23. O’Byrne PM, Reddel HK, Beasley R. The management of mild asthma. Eur Respir J 2021: 57(4).

24. Oldfield K, Ryan J, Doppen M, Kung S, Braithwaite I, Newton-Howes G. A systematic review of the label accuracy of cannabinoidbased products in regulated markets: is what’s on the label what’s in the product? Australas Psychiatry 2021: 29(1): 88-96.

25. Papi A, Braithwaite I, Ebmeier S, Hancox RJ, Harrison T, Holliday M, Houghton C, Morandi L, Oldfield K, Pavord ID, Reddel HK, Williams M, Weatherall M, Beasley R. Budesonide-formoterol reliever therapy in intermittent versus mild persistent asthma. Eur Respir J 2021: 57(2).

26. Parke RL, Gilder E, Gillham MJ, Walker LJC, Bailey MJ, McGuinness SP on behalf of the Fluids After Bypass Study Investigators. A multicentre, open-label, randomized controlled trial of a conservative fluid management strategy compared with usual care in participants after cardiac surgery: the Fluids After Bypass Study. Crit Care Med 2021; 49: 44961.

27. Pilcher JM, Kearns C, Beasley R. Searching for the optimal oxygen saturation range in acutely unwell patients. Emerg Med J 2021; 38: 168-9.

28. Ranta A, Thompson S, Harwood MLN, Cadilhac DA, Barber PA, Davis AJ, Gommans JH, Fink JN, McNaughton HK, Denison H, Corbin M, Feigin V, Abernethy V, Levack W, Douwes J, Girvan J, Wilson A. Reducing Ethnic and Geographic Inequities to Optimise New Zealand Stroke Care (REGIONS Care): Protocol for a Nationwide Observational Study. JMIR Res Protoc 2021: 10(1): e25374.

29. Reddel HK, Vestbo J, Agusti A, Anderson GP, Bansal AT, Beasley R, Bel EH, Janson C, Make B, Pavord ID, Price D, Rapsomaniki E, Karlsson N, Finch DK, Nuevo J, de Giorgio-Miller A, Alacqua M, Hughes R, Mullerova H, Gerhardsson de Verdier M. Heterogeneity within and between physician-diagnosed asthma and/or COPD: NOVELTY cohort. Eur Respir J 2021; doi: 10.1183/13993003.03927-2020.

30. REMAP-CAP, ACTIV-4a, and ATTACC Investigators. Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19. N Engl J Med 2021; 385: 777-89. DOI: 10.1056/ NEJMoa2103417.

31. REMAP-CAP Investigators. Lopinavirritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial. Intensive Care Med. 2021; 47: 867-86.

32. Shaw DE, Heaney LG, Thomas M, Beasley R, Gibson PG, Pavord ID. Balancing the needs of the many and the few: where next for adult asthma guidelines? Lancet Respir Med 2021; doi: 10.1016/S2213-2600(21)00021-7.

33. Wetterslev M, Moller MH, Granholm A, Haase N, Hassager C, Lange T, Hastbacka J, Wilkman E, Myatra SN, Shen J, An Y, Siegemund M, Young PJ, Aslam TN, Szczeklik W, Aneman A, Arabi YM, Cronhjort M, Keus F, Perner A. Newonset atrial fibrillation in the intensive care unit: Protocol for an international inception cohort study (AFIB-ICU). Acta Anaesthesiol Scand 2021.

34. Writing Committee for the REMAP-CAP Investigators. Effect of Convalescent Plasma on Organ Support–Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial. JAMA. 2021; 326: 1690–702.

2020

1. Alhazzani W, Belley-Cote E, Moller MH, Angus DC, Papazian L, Arabi YM, Citerio

G, Connolly B, Denehy L, Fox-Robichaud A, Hough CL, Laake JH, Machado FR, Ostermann M, Piraino T, Sharif S, Szczeklik W, Young PJ, Gouskos A, Kiedrowski K, Burns KEA. Neuromuscular blockade in patients with ARDS: a rapid practice guideline. Intensive Care Med 2020; 46: 1977-86.

2. Angus DC, Berry S, Lewis RJ, Al-Beidh F, Arabi Y, van Bentum-Puijk W, Bhimani Z, Bonten M, Broglio K, Brunkhorst F, Cheng AC, Chiche

JD, De Jong M, Detry M, Goossens H, Gordon

A, Green C, Higgins AM, Hullegie SJ, Kruger P, Lamontagne F, Litton E, Marshall J, McGlothlin

A, McGuinness S, Mouncey P, Murthy S, Nichol

A, O’Neill GK, Parke R, Parker J, Rohde G, Rowan

K, Turner A, Young P, Derde L, McArthur C, Webb

SA. The Randomized Embedded Multifactorial Adaptive Platform for Community-acquired Pneumonia (REMAP-CAP) Study: Rationale and design. Ann Am Thorac Soc 2020; 17: 879-91.

3. Angus DC, Derde L, Al-Beidh F, Annane

D, Arabi Y, Beane A, van Bentum-Puijk W, Berry

L, Bhimani Z, Bonten M, Bradbury C, Brunkhorst

F, Buxton M, Buzgau A, Cheng AC, de Jong M, Detry M, Estcourt L, Fitzgerald M, Goossens

H, Green C, Haniffa R, Higgins AM, Horvat C, Hullegie SJ, Kruger P, Lamontagne F, Lawler PR, Linstrum K, Litton E, Lorenzi E, Marshall J, McAuley D, McGlothin A, McGuinness S, McVerry

B, Montgomery S, Mouncey P, Murthy S, Nichol

A, Parke R, Parker J, Rowan K, Sanil A, Santos

M, Saunders C, Seymour C, Turner A, van de Veerdonk F, Venkatesh B, Zarychanski R, Berry

S, Lewis RJ, McArthur C, Webb SA, Gordon AC. Effect of hydrocortisone on mortality and organ support in patients with severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain

Randomized Clinical Trial. JAMA 2020; 324: 1317-29.

4. ARISE Fluids Investigators. The Australasian Resuscitation In Sepsis Evaluation: Fluids or vasopressors in emergency department sepsis (ARISE FLUIDS), a multicentre observational study describing current practice in Australia and New Zealand. Emerg Med Australas 2020; 32: 586-98.

5. Armour M, Semprini A, Ee C, MacCullagh L, Shortt N. Efficacy of a topical herbal and mineral formulation (Dynamiclear) for the treatment of herpes simplex labialis in the community setting: study protocol for a randomised, double-blind placebo-controlled trial. BMJ Open 2020; 10: e031876.

6. Armour M, Sinclair J, Noller G, Girling J, Larcombe M, Al-Dabbas MA, Hollow E, Bush D, Johnson N. Illicit Cannabis Usage as a Management Strategy in New Zealand Women with Endometriosis: An Online Survey. J Womens Health (Larchmt) 2020.

7. Baggott C, Beasley R. Asthma in the anti-inflammatory reliever therapy era. Lancet Respir Med 2020; doi.org/10.1016/S22132600(20)30465-3.

8. Baggott C, Chan A, Hurford S, Fingleton J, Beasley R, Harwood M, Reddel HK, Levack WMM. Patient preferences for asthma management: a qualitative study. BMJ Open 2020; 10: e037491.

9. Baggott C, Hansen P, Hancox RJ, Hardy JK, Sparks J, Holliday M, Weatherall M, Beasley R, Reddel HK, Fingleton J. What matters most to patients when choosing treatment for mildmoderate asthma? Results from a discrete choice experiment. Thorax 2020: 75(10): 842-8.

10. Baggott C, Hardy J, Sparks J, Holliday M, Hall D, Vohlidkova A, Hancox RJ, Weatherall M, Fingleton J, Beasley R. Self-titration of inhaled corticosteroid and ß2-agonist in response to symptoms in mild asthma – prespecified analysis from the PRACTICAL study, a randomised controlled trial. Eur Respir J 2020; 56(4): 2000170.

11. Baggott C, Reddel HK, Hardy J, Sparks J, Holliday M, Corin A, Montgomery B, Reid J, Sheahan D, Hancox RJ, Weatherall M, Beasley R, Fingleton J. Patient preferences for symptomdriven or regular preventer treatment in mild to moderate asthma — findings from the PRACTICAL study, a randomised clinical trial. Eur Respir J 2020; 55(4): 1902073.

12. Bagshaw SM, Wald R, Adhikari NKJ, Bellomo R, da Costa BR, Dreyfuss D, Du B, Gallagher MP, Gaudry S, Hoste EA, Lamontagne

F, Joannidis M, Landoni G, Liu KD, McAuley DF, McGuinness SP, Neyra JA, Nichol AD, Ostermann

M, Palevsky PM, Pettila V, Quenot JP, Qiu H, Rochwerg B, Schneider AG, Smith OM, Thome

F, Thorpe KE, Vaara S, Weir M, Wang AY, Young

P, Zarbock A. Timing of initiation of renalreplacement therapy in acute kidney injury. N Engl J Med 2020; 383: 240-51.

13. Beasley R, Beckert L, Fingleton J, Hancox RJ, Harwood M, Hurst M, Jones S, Kearns C, McNamara D, Poot B, Reid J. Asthma and Respiratory Foundation NZ Adolescent and Adult Asthma Guidelines 2020: a quick reference guide. NZ Med J 2020; 133: 73-99.

14. Beasley R, Braithwaite I, Semprini

A, Kearns C, Weatherall M, Harrison T, Papi A, Pavord ID. Achieving the balance between evidence and simplicity. Eur Respir J 2020; 55(4): 2000651.

15. Beasley R, Braithwaite I, Semprini A, Kearns C, Weatherall M, Harrison TW, Papi A, Pavord ID. ICS-formoterol reliever therapy stepwise treatment algorithm for adult asthma. Eur Respir J 2020; 55(1): 1901407.

16. Beasley R, Braithwaite I, Semprini A, Kearns C, Weatherall M, Pavord ID. Optimal asthma control: time for a new target. Am J Respir Crit Care Med 2020; 201: 1480-7.

17. Beasley R, Gibson P. Twenty-five years of Respirology: Advances in asthma. Respirology 2020; 25: 11-13.

18. Beasley R, Hancox RJ. Reducing the burden of asthma: time to set research and clinical priorities. Lancet Respir Med 2020; 8: 943-4.

19. Beasley R, Harper J, Masoli M. Antiinterleukin-5 therapy in patients with severe asthma: from clinical trials to clinical practice. Lancet Respir Med 2020; 8: 425-7.

20. Bellomo R, Wunderink RG, Szerlip H, English SW, Busse LW, Deane AM, Khanna AK, McCurdy MT, Ostermann M, Young PJ, Handisides DR, Chawla LS, Tidmarsh GF, Albertson TE. Angiotensin I and angiotensin II concentrations and their ratio in catecholamine-resistant vasodilatory shock. Crit Care 2020; 24: 43.

21. Berenyi F, Steinfort DP, Ali Abdelhamid Y, Bailey MJ, Pilcher DV, Bellomo R, Finnis ME, Young PJ, Deane AM. Characteristics and outcomes of critically ill patients with acute exacerbation of chronic obstructive pulmonary disease in Australia and New Zealand. Ann Am Thorac Soc 2020; 17: 736-45.

22. Berg MVD, John M, Black M, Semprini A, Oldfield K, Glass M, Braithwaite I. Cannabisbased medicinal products in arthritis, a painful conundrum. NZ Med J 2020; 133: 35-45.

23. Bhagavan C, Kung S, Doppen M, John M, Vakalalabure I, Oldfield K, Braithwaite I, Newton-Howes G. Cannabinoids in the Treatment of Insomnia Disorder: A Systematic Review and Meta-Analysis. CNS Drugs 2020: 34(12): 1217-1228.

24. Boudewijn IM, Lan A, Faiz A, Cox CA, Brouwer S, Schokker S, Vroegop SJ, Nawijn MC, Woodruff PG, Christenson SA, Hagedoorn P, Frijlink HW, Choy DF, Brouwer U, Wisman M, Postma DS, Fingleton J, Beasley R, van den Berge M, Guryev V. Nasal gene expression changes with inhaled corticosteroid treatment in asthma. Allergy 2020; 75: 191-4.

25. Braithwaite I, Bhagavan C, Doppen M, Kung S, Oldfield K, Newton-Howes G. Medicinal applications of cannabis/cannabinoids. Curr Opin Psychol 2020; 38: 1-10.

26. Brown SGA, Ball EL, Perrin K, Asha SE, Braithwaite I, Egerton-Warburton D, Jones PG, Keijzers G, Kinnear FB, Kwan BCH, Lam KV, Lee YCG, Nowitz M, Read CA, Simpson G, Smith JA, Summers QA, Weatherall M, Beasley R. Conservative versus Interventional Treatment for Spontaneous Pneumothorax. N Engl J Med 2020: 382(5): 405-15.

27. Brown SGA, Perrin K, Ball EL. Treatment for Pneumothorax [Correspondence Reply]. N Engl J Med 2020; 382(18): 176.

28. Bruce P, Hatter L, Beasley R. Antiinflammatory reliever therapy in asthma: the evidence mounts but more is needed. Respirol 2020; 25: 776-8.

29. Carr AC, Spencer E, Mackle D, Hunt A, Judd H, Mehrtens J, Parker K, Stockwell Z, Gale C, Beaumont M, Kaur S, Bihari S, Young PJ. The effect of conservative oxygen therapy on systemic biomarkers of oxidative stress in critically ill patients. Free Radic Biol Med 2020; 160: 13-8.

30. Conway A, Collins P, Chang K, Mafeld S, Sutherland J, Fingleton J, Parotto M. Pre-apneic capnography waveform abnormalities during procedural sedation and analgesia. J Clin Monit Comput 2020; 34: 1061-8.

31. Darvall JN, Bellomo R, Bailey M, Paul E, Young PJ, Rockwood K, Pilcher D. Frailty and outcomes from pneumonia in critical illness: a population-based cohort study. Br J Anaesth 2020; 125: 730-8.

32. Darvall JN, Bellomo R, Young PJ, Rockwood K, Pilcher D. Frailty and mortality in patients with COVID-19. Lancet Public Health 2020: 5(11): e580.

33. Deane AM, Little L, Bellomo R, Chapman MJ, Davies AR, Ferrie S, Horowitz M, Hurford S, Lange K, Litton E, Mackle D, O’Connor S, Parker J, Peake SL, Presneill JJ, Ridley EJ, Singh V, van Haren F, Williams P, Young P, Iwashyna TJ. Outcomes six-months after

100% or 70% of enteral calorie requirements during critical illness (TARGET): a randomized controlled trial. Am J Respir Crit Care Med 2020; 201: 814-22.

34. Foster JM, Beasley R, Braithwaite I, Harrison T, Holliday M, Pavord I, Reddel HK. Patient experiences of as-needed budesonideformoterol by Turbuhaler® for treatment of mild asthma; a qualitative study. Respir Med 2020; 175: 106154.

35. Frei D, Young PJ. Where to from here with recommendations for perioperative oxygen therapy? Anaesth Crit Care Pain Med 2020; 39: 755-7.

36. Fu V, Weatherall M, McPherson K, Taylor W, McRae A, Thomson T, Gommans J, Green G, Harwood M, Ranta A, Hanger C, Riley J, McNaughton H. Taking Charge after Stroke: A randomized controlled trial of a person-centered, self-directed rehabilitation intervention. Int J Stroke 2020; 1747493020915144.

37. Fujii T, Luethi N, Young PJ, Frei DR, Eastwood GM, French CJ, Deane AM, Shehabi Y, Hajjar LA, Oliveira G, Udy AA, Orford N, Edney SJ, Hunt AL, Judd HL, Bitker L, Cioccari L, Naorungroj T, Yanase F, Bates S, McGain F, Hudson EP, Al-Bassam W, Dwivedi DB, Peppin C, McCracken P, Orosz J, Bailey M, Bellomo R. Effect of vitamin C, hydrocortisone, and thiamine vs hydrocortisone alone on time alive and free of vasopressor support among patients with septic shock: The VITAMINS randomized clinical trial. JAMA 2020; 323: 423-31.

38. Gilder E, McGuinness SP, Cavadino A, Jull A, Parke RL. Avoidance of Routine Endotracheal suction in subjects ventilated for ≤12 h following elective cardiac surgery. Respir Care 2020; 65: 1838-46.

39. Hardy J, Tewhaiti-Smith J, Baggott C, Fingleton J, Semprini A, Holliday M, Hancox RJ, Weatherall M, Harwood M. Combination budesonide/formoterol inhaler as sole reliever therapy in Māori and Pacific people with mild and moderate asthma. NZ Med J 2020; 133: 6172.

40. Harhay MO, Young PJ, Shankar-Hari M. Could stress ulcer prophylaxis increase mortality in high-acuity patients? Intensive Care Med 2020; 46: 793-5.

41. Heaney J, Paul E, Pilcher D, Lin C, Udy A, Young PJ. Outcomes of patients with subarachnoid haemorrhage admitted to Australian and New Zealand intensive care units following a cardiac arrest. Crit Care Resusc 2020; 22: 237-44.

42. Hills T, Arroll N, Duffy E, Capstick J, Jordan A, Fitzharris P. Penicillin allergy de-labelling results in significant changes in antibiotic prescribing patterns. Frontiers in Allergy 2020; doi: 10.3389/falgy.2020.586301.

43. Hills T, Beasley R. The history and future of short-acting beta2-agonist therapy in asthma. Respirology 2020; 25: 246-8.

44. Hills T, Kearns N, Kearns C, Beasley

R. Influenza control during the COVID-19 pandemic. Lancet 2020; 396: 1633-4.

45. Jakobsen JC, Dankiewicz J, Lange

T, Cronberg T, Lilja G, Levin H, Belohlavek J, Callaway C, Cariou A, Erlinge D, Hovdenes J, Joannidis M, Nordberg P, Oddo M, Pelosi P, Kirkegaard H, Eastwood G, Rylander C, Saxena M, Storm C, Taccone FS, Wise MP, Morgan MPG, Young P, Nichol A, Friberg H, Ullen S, Nielsen

N. Targeted hypothermia versus targeted normothermia after out-of-hospital cardiac arrest: a statistical analysis plan. Trials 2020: 21(1): 831.

46. Kearns C, Baggott C, Harwood M, Reid

A, Fingleton J, Levack W, Beasley R. Engaging Māori with qualitative healthcare research using an animated comic. Health Promotional International 2020; doi: 10.1093/heapro/daaa111.

47. Kearns C, Fisher D, Chong YS. The infective nurture of pandemic comics. Lancet 2020; doi: 10.1016/S0140-6736(20)32550-2

48. Kearns C, Kearns N. The role of comics in public health communication during the COVID-19 pandemic. J Visual Comm Med 2020; doi: 10.1080/17453054.2020.1761248.

49. Kearns C, Kearns N, Paisley AM. The art of consent: visual materials help adult patients make informed choices about surgical care. J Vis Commun Med 2020; 43: 76-83.

50. Kearns N, Kearns C, Beasley R. From Osler to personalized medicine in obstructive airways disease. Respirol 2020; 25: 781-3.

51. Kearns N, Maijers I, Harper J, Beasley R, Weatherall M. Inhaled corticosteroids in acute asthma: a systemic review and meta-analysis. J Allergy Clin Immunol Pract 2020; 8: 605-17 e606.

52. Kung SM, Fink PW, Legg SJ, Ali A, Shultz SP. Age-related differences in perceived exertion while walking and running near the preferred transition speed. Pediatr Exerc Sci 2020; 1-6.

53. Lilja G, Nielsen N, Ullen S, Blennow Nordstrom E, Dankiewicz J, Friberg H, Heimburg K, Jakobsen JC, Levin H, Callaway C, Cariou A, Eastwood GM, Helbok R, Hovdenes J, Kirkegaard H, Leithner C, Morgan MPG, Nordberg P, Oddo M, Pelosi P, Rylander C, Saxena M, Taccone FS, Siranec M, Wise MP, Young PJ, Cronberg T. Protocol for outcome reporting and follow-up in the Targeted Hypothermia versus Targeted Normothermia after Out-of-Hospital Cardiac Arrest trial (TTM2). Resuscitation 2020; 150: 104-12.

54. Mackle D, Bellomo R, Bailey M, Beasley R, Deane A, Eastwood G, Finfer S, Freebairn R, King V, Linke N, Litton E, McArthur C, McGuinness S, Panwar R, Young P. Conservative oxygen therapy for mechanically ventilated adults in the Intensive Care Unit. N Engl J Med 2020; 382: 989-98.

55. Maijers I, Kearns N, Harper J, Weatherall M, Beasley R. Oral steroid-sparing effect of high-dose inhaled corticosteroids in asthma. Eur Respir J 2020; 55(1): 1901147.

56. Martin MJ, Beasley R, Harrison TW. Towards a personalised treatment approach for asthma attacks. Thorax 2020; 75: 1119-29.

57. Masse MH, Menard J, Sprague S, Battista MC, Cook DJ, Guyatt GH, Heyland DK, Kanji S, Pinto R, Day AG, Cohen D, Annane D, McGuinness S, Parke R, Carr A, Arabi Y, Vijayaraghavan BKT, D’Aragon F, Carbonneau E, Maslove D, Hunt M, Rochwerg B, Millen T, Chasse M, Lebrasseur M, Archambault P, Deblois E, Drouin C, Lellouche F, Lizotte P, Watpool I, Porteous R, Clarke F, Marinoff N, Belley-Cote E, Bolduc B, Walker S, Iazzetta J, Adhikari NKJ, Lamontagne F. Lessening Organ dysfunction with VITamin C (LOVIT): protocol for a randomized controlled trial. Trials 2020; 21: 42.

58. McNaughton A, Levack W, McNaughton H. Taking charge: a proposed psychological intervention to improve pulmonary rehabilitation outcomes for people with COPD. Int J Chron Obstruct Pulmon Dis 2020; 15: 212733.

59. Oldfield K, Braithwaite I, Beasley R, Eathorne A, Newton-Howes G, Semprini A. Medical cannabis: knowledge and expectations in a cohort of North Island New Zealand general practitioners. NZ Med J 2020; 133: 12-28.

60. Oldfield K, Eathorne A, Maijers I, Beasley R, Semprini A, Braithwaite I. Knowledge and perspectives about the use of cannabis as a medicine: a mixed methods observational study in a cohort of New Zealand general practice patients. NZ Med J 2020; 133: 96-111.

61. Oldfield K, Eathorne A, TewhaitiSmith, Beasley R, Semprini A, Braithwaite I. Experiences, patient interactions and knowledge regarding the use of cannabis as a medicine in a cohort of New Zealand doctors in an oncology setting. Postgrad Med J 2020; 10.1136/postgradmedj-2020-139013.

62. Pavord ID, Holliday M, Reddel HK, Braithwaite I, Ebmeier S, Hancox RJ, Harrison T, Houghton C, Oldfield K, Papi A, Williams M, Weatherall M, Beasley R. Predictive value of blood eosinophils and exhaled nitric oxide in adults with mild asthma: a prespecified subgroup analysis of an open-label, parallelgroup, randomised controlled trial. Lancet Respir Med 2020; 8: 671-80.

63. Peng S, Huang L, Zhao B, Zhou S, Braithwaite I, Zhang N, Fu X. Clinical course of coronavirus disease 2019 in 11 patients after thoracic surgery and challenges in diagnosis. J Thorac Cardiovasc Surg 2020; 160: 585-92. e2.

64. Pilcher J, Ploen L, McKinstry S, Bardsley G, Chien J, Howard L, Lee S, Beckert L, Swanney M, Weatherall M, Beasley R. A multicentre prospective observational study comparing arterial blood gas values to those obtained by pulse oximeters used in adult patients attending Australian and New Zealand hospitals. BMC Pulm Med 2020; 20: 7.

65. Pilcher J, Thayabaran D, Ebmeier S, Williams M, Back G, Collie H, Richards M, Bibby S, Semprini R, Weatherall M, Beasley R. The effect of 50% oxygen on PtCO2 in patients with stable COPD, bronchiectasis, and neuromuscular disease or kyphoscoliosis: randomised cross-over trials. BMC Pulm Med 2020; 20: 125.

66. Poole AP, Finnis ME, Anstey J, Bellomo R, Bihari S, Biradar V, Doherty S, Eastwood G, Finfer S, French CJ, Ghosh A, Heller S, Horowitz M, Kar P, Kruger PS, Maiden MJ, Martensson J, McArthur CJ, McGuinness SP, Secombe PJ, Tobin AE, Udy AA, Young PJ, Deane AM. Study protocol and statistical analysis plan for the Liberal Glucose Control in Critically Ill Patients with Pre-existing Type 2 Diabetes (LUCID) trial. Crit Care Resusc 2020; 22: 133-41.

67. Reid AL, Chapman MJ, Peake SL, Bellomo R, Davies A, Deane AM, Horowitz M, Hurford S, Lange K, Little L, Mackle D, O’Connor SN, Ridley EJ, Williams PJ, Young PJ. Energydense vs routine enteral nutrition in New Zealand Europeans, Māori, and Pacific Peoples who are critically ill. NZ Med J 2020; 133: 72-82.

68. Reid A, Young P. What intensivists can learn from geriatric medicine. ICU Management and Practice 2020; 20(3).

69. Tan E, Braithwaite I, McKinlay C, Riley J, Hoare K, Okesene-Gafa K, Semprini A, Sheridan N, Grant C, Johnson D, Weatherall M, Asher I, Beasley R, Dalziel SR. Randomised controlled trial of paracetamol or ibuprofen, as required for fever and pain in the first year of life, for prevention of asthma at age 6 years: paracetamol or ibuprofen in the primary prevention of asthma in Tamariki (PIPPA Tamariki) protocol. BMJ Open 2020: 10(12): e038296.

70. Thompson S, Barber PA, Fink J, Gommans J, David A, Harwood M, Douwes J, Cadilhac DA, McNaughton H, Girvan J, Abernethy G, Feigin V, Wilson A, Denison H, Corbin M, Levack W, Ranta A. New Zealand hospital stroke service provision. NZ Med J 2020; 133(1526).

71. Van den Berg M, John M, Black M, Semprini A, Oldfield K, Glass M, Braithwaite I. Cannabis-based products in arthritis: a painful conundrum. NZ Med J 2020; 133: 35-45.

72. Warrillow S, Fisher C, Tibballs H, Bailey M, McArthur C, Lawson-Smith P, Prasad B, Anstey M, Venkatesh B, Dashwood G, Walsham J, Holt A, Wiersema U, Gattas D, Zoeller M, Garcia Alvarez M, Bellomo R. Continuous renal replacement therapy and its impact on hyperammonaemia in acute liver failure. Crit Care Resusc 2020; 22: 158-65.

73. Warrillow S, Fisher C, Tibballs H, Bailey M, McArthur C, Lawson-Smith P, Prasad B, Anstey M, Venkatesh B, Dashwood G, Walsham J, Holt A, Wiersema U, Gattas D, Zoeller M, Garcia Alvarez M, Bellomo R. Coagulation abnormalities, bleeding, thrombosis, and management of patients with acute liver failure in Australia and New Zealand. J Gastroenterol Hepatol 2020; 35: 846-54.

74. Wilson AJ, Magee F, Bailey M, Pilcher DV, French C, Nichol A, Udy A, Hodgson CL, Cooper DJ, Reade MC, Young P, Bellomo R. Characteristics and outcomes of critically ill trauma patients in Australia and New Zealand (2005-2017). Crit Care Med 2020; 48: 717-24.

75. Yanase F, Bitker L, Hessels L, Osawa E, Naorungroj T, Cutuli SL, Young PJ, Ritzema J, Hill G, Latimer-Bell C, Hunt A, Eastwood GM, Hilton A, Bellomo R. A pilot, double-blind, randomized, controlled trial of high-dose intravenous vitamin C for vasoplegia after cardiac surgery. J Cardiothorac Vasc Anesth 2020; 34: 409-16.

76. Yanase F, Fujii T, Naorungroj T, Belletti A, Luethi N, Carr AC, Young PJ, Bellomo R. Harm of IV high-dose vitamin C therapy in adult patients: a scoping review. Crit Care Med 2020; 48: e620-e628.

77. Young PJ. Hydrocortisone in septic shock: is it worth it? Crit Care Resusc 2020; 22: 189-90.

78. Young PJ, Bagshaw SM, Bellomo R, Nichol AD, Wright SE. The implications of the PEPTIC trial for clinical practice. Crit Care Resusc. 2020; 22: 4-5.

79. Young PJ, Bagshaw SM, Forbes AB, Nichol AD, Wright SE, Bailey M, Bellomo R, Beasley R, Brickell K, Eastwood GM, Gattas DJ, van Haren F, Litton E, Mackle DM, McArthur CJ, McGuinness SP, Mouncey PR, Navarra L, Opgenorth D, Pilcher D, Saxena MK, Webb SA, Wiley D, Rowan KM. Effect of stress ulcer prophylaxis with proton pump inhibitors vs histamine-2 receptor blockers on in-hospital mortality among ICU patients receiving invasive mechanical ventilation: The PEPTIC randomized clinical trial. JAMA 2020; 323: 616-26.

80. Young PJ, Bagshaw SM, Forbes AB, Nichol AD, Wright SE, Bellomo R, van Haren F, Litton E, Webb SA. Opportunities and challenges of clustering, crossing over, and using registry data in the PEPTIC trial. Crit Care Resusc 2020; 22: 105-9.

81. Young PJ, Bailey M, Bellomo R, Bernard S, Bray J, Jakkula P, Kuisma M, Mackle D, Martin D, Nolan JP, Panwar R, Reinikainen M, Skrifvars MB, Thomas M. Conservative or liberal oxygen therapy in adults after cardiac arrest: An individual-level patient data meta-analysis of randomised controlled trials. Resuscitation 2020: 157: 15-22.

82. Young PJ, Gladwin B, Psirides A, Reid A. Unplanned admissions to the Wellington Hospital intensive care unit before, during and after New Zealand’s COVID-19 lockdown. NZ Med J 2020: 133(1527): 95-103.

83. Young PJ. Stress Ulcer Prophylaxis for ICU Patients-Reply. JAMA 2020; 324: 102-3.

84. Young P, Mackle D, Bellomo R, Bailey M, Beasley R, Deane A, Eastwood G, Finfer S, Freebairn R, King V, Linke N, Litton E, McArthur C, McGuinness S, Panwar R. Conservative oxygen therapy for mechanically ventilated adults with sepsis: a post hoc analysis of data from the intensive care unit randomized trial comparing two approaches to oxygen therapy (ICU-ROX). Intensive Care Med 2020; 46: 17-26.

85. Young P, Mackle D, Bellomo R, Bailey M, Beasley R, Deane A, Eastwood G, Finfer S, Freebairn R, King V, Linke N, Litton E, McArthur C, McGuinness S, Panwar R. Conservative oxygen therapy for mechanically ventilated adults with suspected hypoxic ischaemic encephalopathy. Intensive Care Med 2020; 46: 2411-22.

86. Young P, Mackle D, Bellomo R. Oxygen therapy in the ICU. Reply. N Engl J Med 2020; 382: 2578.

87. Young PJ, Nickson CP, Perner A. When should clinicians act on non-statistically significant results from clinical trials? JAMA 2020; doi: 10.1001/jama.2020.3508.

88. Young PJ, Nickson CP, Perner A. Evaluating Non-Statistically Significant Results From Trials in Practice-Reply. JAMA 2020; 324(16): 1680.

2019

1. Baggott C, Beasley R. Triaging treatable traits in asthma. Respirology 2019: 24(1): 5-6.

2. Beasley R, Bird G, Harper J, Weatherall M. Asthma paradoxes: time for a new approach across the spectrum of asthma severity. Eur Respir J 2019; 53(4): 180239.

3. Beasley R, Harper J, Bird G, Dunphy H, Semprini A, Pavord ID, Papi A, Weatherall M. Dose-response relationship of ICS/fast-onset LABA as reliever therapy in asthma. BMC Pulm Med 2019: 19: 264.

4. Beasley R, Harper J, Bird G, Maijers I, Weatherall M, Pavord ID. Inhaled Corticosteroid Therapy in Adult Asthma: Time for a New Therapeutic Dose Terminology. Am J Respir Crit Care Med 2019; 199: 1471-7.

5. Beasley R, Holliday M, Reddel HK, Braithwaite I, Ebmeier S, Hancox RJ, Harrison T, Houghton C, Oldfield K, Papi A, Pavord ID, Williams M, Weatherall M. Controlled trial of budesonide-formoterol as needed for mild asthma. N Engl J Med 2019; 380: 2020-30.

6. Beasley R, Mackle D, Young P. Oxygen: a new look at an old therapy. J Roy Soc NZ 2019; 49: 126-42.

7. Beasley R, Mackle D. Increased risk of mortality with liberal oxygen therapy compared with conservative oxygen therapy in critically ill adults. BMJ Evid Based Med 2019; 24: 113-4

8. Bird G, Braithwaite I, Harper J, McKinstry S, Koorevaar I, Fingleton J, Semprini A, Dilcher M, Jennings L, Weatherall M, Beasley R. Protocol for a randomised, single-blind, two-arm, parallel-group controlled trail of the efficacy of rhinothermy delivered by nasal high flow therapy in the treatment of the common cold. BMJ Open 2019; 9: e028098.

9. Braithwaite I, Newton-Howes G, Oldfield K, Semprini A. Cannabis-based medicinal products and the role of the doctor: should we be cautious or cautiously optimistic? NZ Med J 2019; 132: 82-8.

10. Chalmers C, Leathem J, Bennett S, McNaughton H, Mahawish K. The efficacy of problem solving therapy to reduce post stroke emotional distress in younger (18-65) stroke survivors. Disabil Rehabil 2019; 41: 753-62.

11. Conway A, Collins P, Chang K, Mafeld S, Sutherland J, Fingleton J. Sequence analysis of capnography waveform abnormalities during nurse-administered procedural sedation and analgesia in the cardiac catheterization laboratory. Sci Rep 2019; 9: 10214.

12. Conway A, Tipton E, Liu WH, Conway Z, Soalheira K, Sutherland J, Fingleton J. Accuracy and precision of transcutaneous carbon dioxide monitoring: a systematic review and metaanalysis. Thorax 2019; 74: 157-63.

13. Dankiewicz J, Cronberg T, Lilja G, Jakobsen JC, Belohlavek J, Callaway C, Cariou

A, Eastwood G, Erlinge D, Hovdenes J, Joannidis

M, Kirkegaard H, Kuiper M, Levin H, Morgan MPG, Nichol AD, Nordberg P, Oddo M, Pelosi P, Rylander C, Saxena M, Storm C, Taccone F, Ullen S, Wise MP, Young P, Friberg H, Nielsen

N. Targeted hypothermia versus targeted Normothermia after out-of-hospital cardiac arrest (TTM2): A randomized clinical trialRationale and design. Am Heart J 2019; 217: 23-31.

14. Denton E, Hore-Lacy F, Radhakrishna

N, Gilbert A, Tay T, Lee J, Dabscheck E, Harvey ES, Bulathsinhala L, Fingleton J, Price D, Gibson PG, O’Hehir R, Hew M. Severe Asthma Global Evaluation (SAGE): An Electronic Platform for Severe Asthma. J Allergy Clin Immunol Pract 2019; 7: 1440-9.

15. Frei DR, Beasley R, Campbell D, Leslie K, Merry AF, Moore M, Myles PS, RuawaiHamilton L, Short TG, Young PJ. Practice patterns and perceptions of Australian and New Zealand anaesthetists towards perioperative oxygen therapy. Anaesth Intensive Care 2019; 47(3): 288-94.

16. Fujii T, Belletti A, Carr A, Furukawa TA, Luethi N, Putzu A, Sartini C, Salanti G, Tsujimoto Y, Udy AA, Young PJ, Bellomo R. Vitamin C therapy for patients with sepsis or septic shock: a protocol for a systematic review and a network meta-analysis. BMJ Open 2019; 9: e033458.

17. Fujii T, Udy AA, Deane AM, Luethi N, Bailey M, Eastwood GM, Frei D, French C, Orford N, Shehabi Y, Young PJ, Bellomo R. Vitamin C, Hydrocortisone and Thiamine in Patients with Septic Shock (VITAMINS) trial: study protocol and statistical analysis plan. Crit Care Resusc 2019; 21(2): 119-25.

18. Gilder E, Parke RL, McGuinness S, Jull A. Study protocol: A randomized controlled trial assessing the avoidance of endotracheal suction in cardiac surgical patients ventilated for ≤12 hr. J Adv Nurs 2019; 75: 2006-14.

19. Hammond NE, Bellomo R, Gallagher M, Gattas D, Glass P, Mackle D, Micallef S, Myburgh J, Saxena M, Taylor C, Young P, Finfer S. The Plasma-Lyte 148 versus Saline (PLUS) study protocol amendment. Crit Care Resusc 2019; 21: 284-6.

20. Hardy J, Baggott C, Fingleton J, Reddel HK, Hancox RJ, Harwood M, Corin A, Sparks J, Hall D, Sabbagh D, Mane S, Vohlidkova A, Martindale J, Williams M, Shirtcliffe P, Holliday M, Weatherall M, Beasley R, on behalf of the PRACTICAL study team. Budesonide-formoterol reliever therapy versus maintenance budesonide plus terbutaline reliever therapy in adults with mild to moderate asthma (PRACTICAL): a 52-week, open-label, multicentre, superiority, randomised controlled trial. Lancet 2019; 394: 919-28.

21. Hessels L, Coulson TG, Seevanayagam S, Young P, Pilcher D, Marhoon N, Bellomo R. Development and Validation of a Score to Identify Cardiac Surgery Patients at High Risk of Prolonged Mechanical Ventilation. J Cardiothorac Vasc Anesth 2019; 33: 2709-16.

22. Landoni G, Pieri M, Young PJ, Bellomo R. Why do multicenter randomized controlled trials not confirm the positive findings of single center randomized controlled trials in acute care? Minerva Anestesiol 2019; 85(2): 194-200.

23. Mackle D, Nelson K. Research nurses in New Zealand intensive care units: A qualitative descriptive study. Aust Crit Care 2019; 32(2): 148-54.

24. Magee F, Wilson A, Bailey MJ, Pilcher D, Secombe PJ, Young P, Bellomo R. Traumarelated admissions to intensive care units in Australia: the influence of Indigenous status on outcomes. Med J Aust 2019; 210: 493-8.

25. McDonald VM, Fingleton J, Agusti A, Hiles SA, Clark VL, Holland AE, Marks GB, Bardin PP, Beasley R, Pavord ID, Wark PAB, Gibson PG. Treatable traits: a new paradigm for 21st century management of chronic airway diseases: Treatable Traits Down Under International Workshop report. Eur Respir J 2019; 53(5): 10.1183/13993003.02058-2018.

26. McKinstry S, Singer J, Baarsma JP, Weatherall M, Beasley R, Fingleton J. Nasal high-flow therapy compared with non-invasive ventilation in COPD patients with chronic respiratory failure: a randomized controlled cross-over trial. Respirology 2019; 24: 1081-7.

27. Morales E, Strachan D, Asher I, Ellwood P, Pearce N, Garcia-Marcos L. Combined impact of healthy lifestyle factors on risk of asthma, rhinoconjunctivitis and eczema in school children: ISAAC phase III. Thorax 2019; 74: 531-8.

28. Pappacena S, Bailey M, Cabrini L, Landoni G, Udy A, Pilcher DV, Young P, Bellomo R. Early dysglycemia and mortality in traumatic brain injury and subarachnoid hemorrhage. Minerva Anestesiol 2019; 85: 830-9.

29. Reddel HK, Gerhardsson de Verdier M, Agusti A, Anderson G, Beasley R, Bel EH, Janson C, Make B, Martin RJ, Pavord I, Price D, Keen C, Gardev A, Rennard S, Sveréus A, Bansal AT, Brannman L, Karlsson N, Nuevo J, Nyberg F, Young SS, Vestbo J. Prospective observational study in patients with obstructive lung disease: NOVELTY design. ERJ Open Res 2019; 5: 000362018.

30. Ridley EJ, Parke RL, Davies AR, Bailey M, Hodgson C, Deane AM, McGuinness S, Cooper DJ. What Happens to Nutrition Intake in the Post-Intensive Care Unit Hospitalization Period? An Observational Cohort Study in Critically Ill Adults. JPEN J Parenter Enteral Nutr 2019; 43(1): 88-95.

31. Sabbagh D, Beasley R, Marks G. The immunological mysteries of tuberculosis. J Allergy Clin Immunol Pract 2019; 7: 649-50.

32. Schlapbach LJ, Horton SB, Long DA, Beca J, Erickson S, Festa M, d’Udekem Y, Alphonso N, Winlaw D, Johnson K, Delzoppo C, van Loon K, Gannon B, Fooken J, Blumenthal A, Young P, Jones M, Butt W, Schibler A. Study protocol: NITric oxide during cardiopulmonary bypass to improve Recovery in Infants with Congenital heart defects (NITRIC trial): a randomised controlled trial. BMJ Open 2019; 9: e026664.

33. Semprini A, Singer J, Braithwaite I, Shortt N, Thayabaran D, McConnell M, Weatherall M, Beasley R. Kanuka honey versus acyclovir for the topical treatment of herpes simplex labialis: a randomised controlled trial. BMJ Open 2019; 9: e026201.

34. Semprini R, Shortt N, Ebmeier S, Semprini A, Varughese R, Holweg CTJ, Matthews JG, Fingleton J, Weatherall M, Beasley R, Braithwaite I. Change in biomarkers of type-2 inflammation following severe exacerbations of asthma. Thorax 2019; 74: 95-8.

35. Sheehan TJ, Hamnett HJ, Beasley R, Fitzmaurice PS. Chemical and physical variations of cannabis smoke from a variety of cannabis samples in New Zealand. Forensic Sci Res 2019; 4(2): 168-78.

36. Warrillow S, Bailey M, Pilcher D, Kazemi A, McArthur C, Young P, Bellomo R. Characteristics and outcomes of patients with acute liver failure admitted to Australian and New Zealand intensive care units. Intern Med J 2019; 49: 874-85.

37. Warrillow S, Tibballs H, Bailey M, McArthur C, Lawson-Smith P, Prasad B, Anstey M, Venkatesh B, Dashwood G, Walsham J, Holt A, Wiersema U, Gattas D, Zoeller M, Garcia Alvarez M, Bellomo R. Characteristics, management and outcomes of patients with acute liver failure admitted to Australasian intensive care units. Crit Care Resusc 2019; 21: 188-99.

38. Webster M, Stewart R, Aagaard N, McArthur C. The learning health system: trial design and participant consent in comparative effectiveness research. Eur Heart J 2019; 40(15): 1236-40.

39. Weinkove R, Bowden E, Wood C, Campion V, Carter J, Hall R, Weatherall M, Beasley R, Young P. A randomized controlled feasibility trial of paracetamol during febrile neutropenia in hemato-oncology patients. Leuk Lymphoma 2019; 60: 1540-7.

40. Young PJ. Balanced crystalloids or 0.9% saline in sepsis. Beyond reasonable doubt? Am J Respir Crit Care Med 2019; 200: 1456-8.

41. Young PJ, Bagshaw SM, Bailey M, Bellomo R, Mackle D, Pilcher D, Landoni G, Nichol A, Martin D. O2, do we know what to do? Crit Care Resusc 2019; 21: 230-2.

42. Young PJ, Bailey MJ, Bass F, Beasley RW, Freebairn RC, Hammond NE, van Haren FMP, Harward ML, Henderson SJ, Mackle DM, McArthur CJ, McGuinness SP, Myburgh JA, Saxena MK, Turner AM, Webb SAR, Bellomo R. Randomised evaluation of active control of temperature versus ordinary temperature management (REACTOR) trial. Intensive Care Med 2019; 45: 1382-91.

43. Young PJ, Bellomo R. The risk of hyperoxemia in ICU patients. Much ado about O2. Am J Respir Crit Care Med 2019; 200: 1333-5.

44. Young PJ, Bellomo R, Bernard GR, Niven DJ, Schortgen F, Saxena M, Beasley R, Weatherall M. Fever control in critically ill adults. An individual patient data meta-analysis of randomised controlled trials. Intensive Care Med 2019; 45: 468-76.

45. Young PJ, Delaney A, Venkatesh B. Vasopressin in septic shock: what we know and where to next? Intensive Care Med 2019; 45: 902-3.

46. Young PJ, Prescott HC. When less is more in the active management of elevated body temperature of ICU patients. Intensive Care Med 2019; 45: 1275-8.

47. Young PJ. Is sepsis treatment heating up? Crit Care Resusc 2019; 21: 85-6.

2018

1. Abrams D, Garan AR, Abdelbary A, Bacchetta M, Bartlett RH, Beck J, Belohlavek J, Chen YS, Fan E, Ferguson ND, Fowles JA, Fraser J, Gong M, Hassan IF, Hodgson C, Hou X, Hryniewicz K, Ichiba S, Jakobleff WA, Lorusso R, MacLaren G, McGuinness S, Mueller T, Park PK, Peek G, Pellegrino V, Price S, Rosenzweig EB, Sakamoto T, Salazar L, Schmidt M, Slutsky AS, Spaulding C, Takayama H, Takeda K, Vuylsteke A, Combes A, Brodie D. Position paper for the organization of ECMO programs for cardiac failure in adults. Intensive Care Med 2018; 44: 717-29.

2. Al-Bassam W, Kubicki M, Bailey M, Walker L, Young P, Pilcher DV, Bellomo R. Characteristics, incidence, and outcome of patients admitted to the intensive care unit with myasthenia gravis. J Crit Care 2018; 45: 904.

3. Bardsley G, Daley-Yates P, Baines A, Kempsford R, Williams M, Mallon T, Braithwaite I, Riddell K, Joshi S, Bareille P, Beasley R, Fingleton J. Anti-inflammatory duration of action of fluticasone furoate/vilanterol trifenatate in asthma: a cross-over randomised controlled trial. Respir Res 2018;19: 133.

4. Bardsley G, Pilcher J, McKinstry S, Shirtcliffe P, Berry J, Fingleton J, Weatherall M, Beasley R. Oxygen versus air-driven nebulisers for exacerbations of chronic obstructive pulmonary disease: a randomised controlled trial. BMC Pulm Med 2018;18: 157.

5. Beasley R, Braithwaite I, Fingleton J, Weatherall M. The inhaled corticosteroid/ long-acting ß-agonist maintenance and reliever therapy regimen: where to from here? [Editorial]. Eur Respir J 2018; 51: 1702338.

6. Braithwaite I, Semprini R, Beasley R. The clinical relevance of periostin in asthma. BRN Rev 2018; 4: 258-73.

7. Braithwaite I, Shirtcliffe P, Jurevics R, Beasley R. Gaming: a 21st century variant of seated immobility thromboembolism. NZMJ 2018; 131(1469): 66-8.

8. Braithwaite I, Shortt N, Mallon A, Burmeister A, Jeans M, Weatherall M, Beasley R. A non-randomised feasibility study of the Legflow device for sedentary adults in an office environment. Journal of Health, Safety, Environment. 2018; 34(1).

9. Carr A, Wohlrab C, Young P, Bellomo R. Stability of intravenous vitamin C solutions: a technical report. Crit Care Resusc 2018; 20: 1801.

10. Chan L, McNaughton H, Weatherall M. Are physical activity levels of health care professionals consistent with activity guidelines? A prospective cohort study in New Zealand. JRSM Cardiovascular Disease 2018; 7: 1-4.

11. Chapman M, Peake SL, Bellomo R, Davies A, Deane A, Horowitz M, Hurford S, Lange K, Little L, Mackle D, O’Connor S, Presneill J, Ridley E, Williams P, Young P. Energy-Dense versus Routine Enteral Nutrition in the Critically Ill. N Engl J Med 2018; 379(19): 182334.

12. Chu DK, Kim LH, Young PJ, Zamiri N, Almenawer SA, Jaeschke R, Szczeklik W, Schunemann HJ, Neary JD, Alhazzani W. Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and metaanalysis. Lancet 2018;391: 1693-705.

13. Cutuli SL, Osawa EA, Glassford NJ, Marshall D, Eyeington CT, Eastwood GM, Young PJ, Bellomo R. Body temperature measurement methods and targets in Australian and New Zealand intensive care units. Crit Care Resusc 2018;20: 241-44.

14. Dallimore J, Ebmeier S, Thayabaran D, Bellomo R, Bernard G, Schortgen F, Saxena M, Beasley R, Weatherall M, Young P. Effect of active temperature management on mortality in intensive care unit patients. Crit Care Resusc. 2018; 20(2):150-163. PubMed PMID: 29852854.

15. Ebmeier SJ, Barker M, Bacon M, Beasley R, Bellomo R, Knee Chong C, Eastwood GM, Gilchrist J, Hidetoshi K, Pilcher J, Reddy S, Ridgeon E, Sarma N, Sprogis S, Tanaka A, Tweedie M, Weatherall M, and Young PJ. A Two Centre Observational Study of Simultaneous SpO2 and SaO2 Recordings in ICU Patients. Anaesth Intensive Care 2018; 46: 297-303.

16. Fingleton J, Hardy J, Beasley R. Treatable traits of chronic airways disease. Curr Opin Pulmon Med 2018; 24: 24-31.

17. Frei DR, Young PJ. Oxygen therapy in acute resuscitation. Curr Opin Crit Care 2018; 24(6): 506-11.

18. Fuggle NR, Singer J, Clynes MA, Curtis B, Wyawahare P, Denison HJ, Gilmour M, Robinson G, Dennison EM. Risk factors for fracture in alcohol-dependent, pre-menopausal females. IJADR 2018; 7: 2-7.

19. Hills T, Semprini A, Beasley R. Pragmatic randomised clinical trials using electronic health records: general practitioner views on a model of a priori consent. Trials 2018; 19: 278.

20. Mackle DM, Bailey MJ, Beasley RW, Bellomo R, Bennett VL, Deane AM, Eastwood GM, Finfer S, Freebairn RC, Litton E, Linke NJ, McArthur CJ, McGuinness SP, Panwar R, Young PJ; Australian and New Zealand Intensive Care Society Clinical Trials Group. Protocol summary and statistical analysis plan for the intensive care unit randomised trial comparing two approaches to oxygen therapy (ICU-ROX). Crit Care Resusc. 2018 Mar; 20(1): 22-32. PubMed PMID: 29458318.

21. Mane S, Singer J, Corin A, Semprini A. Successful Treatment of Actinic Keratosis with Kanuka Honey. Case Rep Dermatol Med 2018; 2018: 4628971.

22. Mazer CD, Whitlock RP, Fergusson DA, Belley-Cote E, Connolly K, Khanykin B, Gregory AJ, de Medicis E, Carrier FM, McGuinness S, Young PJ, Byrne K, Villar JC, Royse A, Grocott HP, Seeberger MD, Mehta C, Lellouche F, Hare GMT, Painter TW, Fremes S, Syed S, Bagshaw SM, Hwang NC, Royse C, Hall J, Dai D, Mistry N, Thorpe K, Verma S, Juni P, Shehata N. SixMonth Outcomes after Restrictive or Liberal Transfusion for Cardiac Surgery. N Engl J Med 2018; 379: 1224-33.

23. McKinstry S, Pilcher J, Bardsley G, Berry J, Van de Hei S, Braithwaite I, Fingleton J, Weatherall M, Beasley R. Nasal high flow therapy and PtCO2 in stable COPD: A randomized controlled cross-over trial. Respirology 2018; 23: 378-84.

24. McNaughton H, Singh A, Khan SA. An outbreak of Japanese encephalitis in a nonendemic region of north-east India. J R Coll Physicians Edinb 2018; 48: 25-9.

25. Mitchell EA, Stewart AW, Braithwaite I, Murphy R, Hancox RJ, Wall C, Beasley R. Factors associated with body mass index in children and adolescents: An international crosssectional study. PLoS One 2018; 13: e0196221.

26. Murphy R, Stewart AW, Hancox RJ, Wall CR, Braithwaite I, Beasley R, Mitchell EA. Obesity, underweight and BMI distribution characteristics of children by gross national income and income inequality: results from an international survey. Obesity Science & Practice 2018; 4: 216-28.

27. Myles PS, Bellomo R, Corcoran T, Forbes A, Peyton P, Story D, Christophi C, Leslie K, McGuinness S, Parke R, Serpell J, Chan MTV, Painter T, McCluskey S, Minto G, Wallace S. Restrictive versus liberal fluid therapy for major abdominal surgery. N Engl J Med 2018; 378: 2263-74.

28. Parke R, Bihari S, Dixon DL, Gilder E, Cavallaro E, McGuinness S, Bersten AD. Fluid resuscitation associated with elevated angiopoietin-2 and length of mechanical ventilation after cardiac surgery. Crit Care Resusc 2018; 20: 198-208.

29. Parke R, Gilder E, Gillham M, Walker L, Bailey M, McGuinness S. Design and statistical analysis plan for a trial comparing a conservative fluid management strategy with usual care in patients after cardiac surgery: the FAB study. Crit Care Resusc 2018; 20: 190-7.

30. Pavord ID, Beasley R, Agusti A, Anderson GP, Bel E, Brusselle G, Cullinan P, Custovic A, Ducharme FM, Fahy JV, Frey U, Gibson P, Heaney LG, Holt PG, Humbert M, Lloyd CM, Marks G, Martinez FD, Sly PD, von Mutius E, Wenzel S, Zar HJ, Bush A. After asthma: redefining airways diseases. Lancet 2018; 391: 350-400.

31. Ridley EJ, Davies AR, Parke R, Bailey M, McArthur C, Gillanders L, Cooper DJ, McGuinness S. Supplemental parenteral nutrition versus usual care in critically ill adults: a pilot randomized controlled study. Crit Care 2018;22: 12.

32. Sabbagh DK, Barmayehvar B, Nguyen T, Edgar RG, Turner AM. Managing panniculitis in alpha-1 antitrypsin deficiency: systematic review of evidence behind treatment. World J Dermatology 2018; 7(1): 1-8.

33. Salter R, Bailey M, Bellomo R, Eastwood G, Goodwin A, Nielsen N, Pilcher D, Nichol

A, Saxena M, Shehabi Y, Young P. Changes in temperature management of cardiac arrest patients following publication of the Target Temperature Management Trial. Crit Care Med 2018: 46(11): 1722-1730.

34. Semprini R, Williams M, Semprini A, McDouall A, Fingleton J, Holweg C, Weatherall M, Beasley R, Braithwaite I. Type 2 biomarkers and prediction of future exacerbations and lung function decline in adult asthma. J Allergy Clin Immunol Pract 2018; 6: 1982-8.

35. Shehata N, Whitlock R, Fergusson DA, Thorpe KE, MacAdams C, Grocott HP, Rubens

F, Fremes S, Lellouche F, Bagshaw S, Royse

A, Rosseel PM, Hare G, Medicis E, Hudson C, Belley-Cote E, Bainbridge D, Kent B, Shaw A, Byrne K, Syed S, Royse CF, McGuinness S, Hall

J, Mazer CD. Transfusion Requirements in Cardiac Surgery III (TRICS III): Study Design of a Randomized Controlled Trial. J Cardiothorac Vasc Anesth 2018;32: 121-129.

36. Shortt N, Poyntz H, Young W, Jones

A, Gestin A, Mooney A, Thayabaran D, Sparks J, Ostapowicz T, Tay A, Poppitt S, Elliott S, Wakefield G, Parry-Strong A, Ralston J, Gasser O, Beasley R, Weatherall M, Braithwaite I, ForbesBlom E. A feasibility study: association between gut microbiota enterotype and antibody response to seasonal trivalent influenza vaccine in adults. Clin Transl Immunology 2018: 7(3): e1013.

37. Tan E, Varughese R, Semprini R, Montgomery B, Holweg C, Olsson J, CaswellSmith R, Fingleton J, Weatherall M, Beasley R, Braithwaite I. Serum periostin levels in adults of Chinese descent: an observational study. Allergy Asthma Clin Immunol 2018; 14: 87.

38. TARGET investigators on behalf of the ANZICS Clinical Trials Group. Study protocol for The Augmented versus Routine Approach to Giving Energy Trial (TARGET). Crit Care Resusc 2018; 20: 6-14.

39. TARGET investigators on behalf of the ANZICS Clinical Trials Group. Statistical plan for The Augmented versus Routine Approach to Giving Energy Trial (TARGET). Crit Care Resusc 2018; 20: 15-21.

40. Truman P, Gilmour M, Robinson G. Acceptability of electronic cigarettes as an option to replace tobacco smoking for alcoholics admitted to hospital for detoxification. NZMJ 2018; 131: 22-8.

41. Van de Hei S, McKinstry S, Bardsley G, Weatherall M, Beasley R, Fingleton J. Randomised controlled trial of rhinothermy for treatment of the common cold: a feasibility study. BMJ Open 2018; 8: e019350.

42. Varughese R, Semprini R, Munro C, Fingleton J, Holweg C, Weatherall M, Beasley R, Braithwaite I. Serum periostin levels following small bone fractures, long bone fractures and joint replacements: an observational study. Allergy Asthma Clin Immunol 2018: 14: 30.

43. Vincent JL, Nielsen ND, Shapiro NI, Gerbasi ME, Grossman A, Doroff R, Zeng F, Young PJ, Russell JA. Mean arterial pressure and mortality in patients with distributive shock: a retrospective analysis of the MIMIC-III database. Ann Intensive Care. 2018 Nov 8;8(1):107. doi: 10.1186/s13613-018-0448-9.

44. Venkatesh B, Finfer S, Cohen J, Rajbhandari D, Arabi Y, Bellomo R, Billot L, Correa M, Glass P, Harward M, Joyce C, Li Q, McArthur C, Perner A, Rhodes A, Thompson K, Webb S, Myburgh J. Adjunctive glucocorticoid therapy in patients with septic shock. N Engl J Med 2018; 378: 797-808.

45. Wall C, Stewart A, Hancox R, Murphy R, Braithwaite I, Beasley R, Mitchell E. Association between frequency of consumption of fruit, vegetables, nuts and pulses and BMI: analyses of the International Study of Asthma and Allergies in Childhood (ISAAC). Nutrients 2018; 10: 316. Doi:10.3390/nu10030316.

46. Young P. Intensive care unit randomised trial comparing two approaches to oxygen therapy (ICU-ROX): results of the pilot phase. Crit Care Resusc 2018;20: 246-247.

47. Young PJ. Learning healthcare systems will protect patients from unscientific practice variation. Ann Am Thorac Soc 2018; 15: 131-3.

48. Young PJ, Bagshaw SM, Forbes A, Nichol A, Wright SE, Bellomo R, Bailey MJ, Beasley RW, Eastwood GM, Festa M, Gattas D, van Haren F, Litton E, Mouncey PR, Navarra L, Pilcher D, Mackle DM, McArthur CJ, McGuinness SP, Saxena MK, Webb S, Rowan KM. A cluster randomised, crossover, registry-embedded clinical trial of proton pump inhibitors versus histamine-2 receptor blockers for ulcer prophylaxis therapy in the intensive care unit (PEPTIC study): study protocol. Crit Care Resusc 2018;20: 182-189.

49. Young PJ, Nielsen N, Saxena M. Fever control. Intensive Care Med 2018; 44: 227-230.

1. Agusti A, Bafadhel M, Beasley R, Bel EH, Faner R, Gibson PG, Louis R, McDonald VM, Sterk PJ, Thomas M, Vogelmeier C, Pavord ID. Precision medicine in airway diseases: moving to clinical practice. Eur Respir J 2017; 50: 1701655.

2. Beasley R, Chien J, Douglas J, Eastlake, Farah C, King G, Moore R, Pilcher J, Richards M, Smith S, Walters EH. Target oxygen saturation range 92-96% versus 94-98%. Respirology 2017; 22: 200-2.

3. Beasley R, Hancox RJ. New Zealand asthma guidelines updated [Editorial]. NZMJ 2017; 130: 7-9.

4. Beasley R, Hardy J, Hancox R. Asthma prescribing: Where are we headed? Respirology 2017; 22: 1487-8.

5. Beasley R, Thayabaran D, Hancox RJ. Adult asthma quick reference guides: TransTasman differences in opinion. Respirology 2017; 22: 9-11.

6. Beasley R, Weatherall M. Vitamin D and asthma: a case to answer. Lancet Respir Med 2017; 5: 839-40.

7. Billot L, Venkatesh B, Myburgh J, Finfer S, Cohen J, Webb S, McArthur C, Joyce C, Bellomo R, Rhodes A, Perner A, Arabi Y, Rajbhandari D, Glass P, Thompson K, Correa M, Harward M. Statistical analysis plan for the Adjunctive Corticosteroid Treatment in Critically Ill Patients with Septic Shock (ADRENAL) trial. Crit Care Resusc 2017; 19: 18391.

8. Braithwaite I, Healy B, Cameron L, Weatherall M, Beasley R. Lower limb immobilisation and venous thromboembolism risk: combined case-control studies. Postgrad Med J 2017; 93: 354-9.

9. Braithwaite I, Mackintosh S, Buchanan S, Schwarzenlander K, De Ruyter B on behalf of the JIT Study Group. Venous haemodynamics of Jet Impulse Technology within a lower limb fibreglass cast: a randomized controlled trial. JRSM Open 2017; 8: doi: 10.1177/2054270416681746.

10. Braithwaite IE, Stewart AW, Hancox RJ, Murphy R, Wall CR, Beasley R, Mitchell EA and the ISAAC Phase Three Study Group. Body Mass Index and vigorous physical activity in children and adolescents: an international cross-sectional study. Acta Paediatrica 2017; 106: 1323-30.

11. Caswell-Smith R, Cripps T, Charles T, Hosking A, Handigol M, Holweg C, Matthews J, Holliday M, Maillot C, Fingleton J, Weatherall M, Beasley R, Braithwaite I. Day-time variation of serum periostin in asthmatic adults treated with ICS/LABA and adults without asthma. Allergy Asthma Clin Immunol 2017; 13: 8. doi: 10.1186/s13223-017-0182-0.

12. Chang CL, Wong C, Beckert L, Shafuddin E, Beasley R, Young R, Hancox RJ. ß-blockers in exacerbations of COPD: feasibility of a randomised controlled trial. Eur Respir J Open Res 2017; 3: 00090-2016.

13. Cheung W, Myburgh J, McGuinness S, Chalmers D, Parke R, Blyth F, Seppelt I, Parr M, Hooker C, Blackwell N, DeMonte S, Gandhi K, Kol M, Kerridge I, Nair P, Saunders NM, Saxena MK, Thanakrishnan G, Naganathan V. The Influenza Pandemic ICU Triage study investigators, The ANZICS Clinical Trials Group. A cross-sectional survey of Australian and New Zealand public opinion on methods to triage intensive care patients in an influenza pandemic. Crit Care Resusc 2017; 19: 254-65.

14. Cooper DJ, McQuliten Z, Nicol A, Ady, B, Aubron, C, Bailey M, Bellomo R, Gantner D, Irving D, Kaukonen KM, McArthur C, Murray L, Pettila V, French C, for the TRANSFUSE Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Age of red cells for transfusion and outcomes in critically ill adults. N Engl J Med 2017; 377: 1858-67.

15. Deane AM, Hodgson CL, Young P, Little L, Singh V, Poole A, Young M, Mackle D, Lange K, Williams P, Peake SL, Chapman MJ, Iwashyna TJ. The rapid and accurate categorisation of critically ill patients (RACE) to identify outcomes of interest for longitudinal studies: a feasibility study. Anaesth Intensive Care 2017; 45: 476-84.

16. Ebmeier S, Thayabaran D, Braithwaite I, Bénamara C, Weatherall M, Beasley R. Trends in international asthma mortality: analysis of data from the WHO Mortality Database from 46 countries (1993-2012). Lancet 2017; 390: 935-45.

17. Fingleton J, Hardy J, Baggott C, Pilcher J, Corin A, Hancox RJ, Harwood M, Holliday M, Reddel HK, Shirtcliffe P, Snively S, Weatherall M, Beasley R. Description of the protocol for the PRACTICAL study: a randomised controlled trial of the efficacy and safety of ICS/LABA reliever therapy in asthma. BMJ Open Resp Res 2017; 4: e000217. doi:10.1136/ bmjresp-2017-000217.

18. Fingleton J, Huang K, Weatherall M, Guo Y, Ivanov S, Bruijnzeel P, Zhang H, Wang W, Beasley R, Wang C for the NZRHS Study Group. Phenotypes of obstructive airways disease in China and New Zealand. Eur Respir J 2017; 10.1183/13993003.00957-2017.

19. Fu VWY, Weatherall M, McNaughton H. The Taking Charge After Stroke (TaCAS) study protocol: a multicentre, investigator-blinded, randomised controlled trial comparing the effect of a single Take Charge session, two Take Charge sessions and control intervention on health-related quality of life 12 months after stroke for non-Māori, non-Pacific adult New Zealanders discharged to community living. BMJ Open 2017; 7: e016512. doi:10.1136/ bmjopen-2017-016512.

20. Hammond NE, Bellomo R, Gallagher M, Gattas D, Glass P, Mackle D, Micallef S, Myburgh J, Saxena M, Taylor C, Young P, Finfer

S. The Plasma-Lyte 148 vs. Saline (PLUS) study protocol: a multicentre, randomised controlled trial of the effect of intensive care fluid therapy on mortality. Crit Care Resusc 2017; 19: 239-46.

21. Hammond NE, Taylor C, Finfer S, Machado FR, An Y, Billot L, Bloos F, Bozza F, Cavalcanti AB, Correa M, Du B, Hjortrup PB, Li Y, McIntryre L, Saxena M, Schortgen F, Watts NR, Myburgh J, The Fluid Trips Investigators, The George Institute for Global Health TACTG, BRICNet, the RrN. Patterns of intravenous fluid resuscitation use in adult intensive care patients between 2007 and 2014: An international cross-sectional study. PLoS One 2017; 12: e0176292.

22. Khanna A, English SW, Wang XS, Ham K, Tumlin J, Szerlip H, Busse LW, Altaweel L, Albertson TE, Mackey C, McCurdy MT, Boldt DW, Chock S, Young PJ, Krell K, Wunderink RG, Ostermann M, Murugan R, Gong MN, Panwar R, Hastbacka J, Favory R, Venkatesh B, Thompson BT, Bellomo R, Jensen J, Kroll S, Chawla LS, Tidmarsh GF, Deane AM. Angiotensin II for the Treatment of Vasodilatory Shock. N Engl J Med 2017; 377: 419-30.

23. Mazer CD, Whitlock RP, Fergusson DA, Hall J, Belley-Cote E, Connolly K, Khanykin B, Gregory AJ, de Medicis E, McGuinness S, Royse A, Carrier FM, Young PJ, Villar JC, Grocott HP, Seeberger MD, Fremes S, Lellouche F, Syed S, Byrne K, Bagshaw SM, Hwang NC, Mehta C, Painter TW, Royse C, Verma S, Hare GMT, Cohen A, Thorpe KE, Juni P, Shehata N. Restrictive or liberal red-cell transfusion for cardiac surgery. N Engl J Med 2017; 377: 2133-44.

24. McArthur C. Glycaemic control in diabetic ketoacidosis: Too much of a good thing? [Editorial]. Crit Care Resus 2017; 19: 195-6.

25. McNaughton A, Weatherall M, Williams M, McNaughton H, Aldington S, Williams G, Beasley R. Sing Your Lungs Out — A community singing group for chronic obstructive pulmonary disease: a one-year pilot study. BMJ Open 2017; 7: e014151.

26. Mitchell EA, Stewart AW, Braithwaite I, Hancox RJ, Murphy R, Wall C, Beasley R. Birth weight and subsequent body mass index in children: an international cross-sectional study. Pediatr Obes 2017; 12: 280-5.

27. Myles P, Bellomo R, Corcoran T, Forbes A, Wallace S, Peyton P, Christophi C, Story D, Leslie K, Serpell J, McGuinness S, Parke R, The ANZCA Clinical Trials Network, The ANZICS Clinical Trials Group. Restrictive versus liberal fluid therapy in major abdominal surgery (RELIEF): rationale and design for a multicentre randomised trial. BMJ open 2017; 7: e015358.

28. Myles PS, Smith JA, Forbes A, Silbert B, Jayarajah M, Painter T, Cooper DJ, Marasco S, McNeil J, Bussieres JS, McGuinness S, Byrne K, Chan MT, Landoni G, Wallace S, The ATACAS Investigators of the ANZCA Clinical Trials Network. Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery. N Engl J Med 2017; 376: 136-48.

29. O’Brien Z, Cass A, Cole L, Finfer S, Gallagher M, McArthur C, McGuiness S, Myburgh J, Bellomo R, Mårtensson J, on behalf of the RENAL Study Investigators and the Australian and New Zealand Intensive Care Clinical Trials Group. Higher versus lower continuous renal replacement therapy intensity in critically ill patients with liver dysfunction. Blood Purification 2017; 45: 36-43.

30. O’Driscoll BR, Howard LS, Earis J, Mak V, on behalf of the British Thoracic Society

Emergency Oxygen Guideline Group. BTS guideline for oxygen use in adults in healthcare and emergency settings: Summary. BMJ Open Respir Res 2017; 4: e000170. doi:10.1136/ bmjresp-2016-000170.

31. O’Driscoll BR, Howard LS, Earis J, Mak V, on behalf of the British Thoracic Society

Emergency Oxygen Guideline Development Group. BTS guideline for oxygen use in adults in healthcare and emergency settings. Thorax 2017; 72(Suppl 1): i1-i90.

32. Parke RL, McGuinness S, Eastwood GM, Nichol A, Nielsen N, Dankiewicz J, Bellomo R. Co-enrolment for the TAME and TTM-2 trials: the cerebral option. Crit Care Resusc 2017; 19: 99-100.

33. Perner A, Prowle J, Joannidis M, Young P, Hjortrup P, Pettilä V. Fluid management in acute kidney injury. Intensive Care Med 2017; 43: 807-15.

34. Pilcher J, Eastlake L, Richards M, Power S, Cripps T, Bibby S, Braithwaite I, Weatherall M, Beasley R. Physiological effects of titrated oxygen via nasal high flow cannulae in COPD exacerbations: a randomised controlled crossover trial. Respirology 2017; 22: 1149-55.

35. Pilcher J, Patel M, Pritchard A, Thayabaran D, Ebmeier S, Shaw D, Black P, Braithwaite I, Weatherall M, Beasley R. Betaagonist overuse and delay in obtaining medical review in high risk asthma: a secondary analysis of data from a randomised controlled trial. NPJ Prim Care Respir Med 2017; 27: 33. doi:10.1038/ s41533-017-0032-z.

36. Pilcher J, Richards M, Eastlake L, McKinstry SJ, Bardsley G, Jefferies S, Braithwaite I, Weatherall M, Beasley R. High flow or titrated oxygen for obese medical inpatients: a randomised crossover trial. Med J Aust 2017; 207: 430-4.

37. Power S, Williams M, Semprini A, Munro C, Caswell-Smith R, Pilcher J, Holliday M, Fingleton J, Harper J, Hurst R, Weatherall M, Beasley R, Braithwaite I. RCT of the effect of berryfruit polyphenolic cultivar extract in mild steroid-naïve asthma: a cross-over, placebocontrolled study. BMJ Open 2017; 7: e013850.

38. Reddy SK, Bailey MJ, Beasley RW, Bellomo R, Mackle DM, Psirides AJ, Young PJ. Effect of 0.9% saline or Plasma-Lyte 148 as crystalloid fluid therapy in the Intensive Care Unit on blood product use and postoperative bleeding after cardiac surgery. J Cardiothoracic Vasc Anesthesia 2017; 31: 1630-8.

39. Ridgeon EE, Bellomo R, Aberegg SK, Mac Sweeney R, Varughese RS, Landoni G, Young PJ. Effect sizes in ongoing randomized controlled critical care trials. Crit Care 2017; 21: 132. doi: 10.1186/s13054-017-1726-x.

40. Semprini A, Hills T, Braithwaite I, Weatherall M, Beasley R. A priori consent within pragmatic randomised controlled trials: a webbased survey of statin use in primary care. BMJ Innov 2017; 3: 206-11.

41. Semprini A, Singer J, Shortt N, Braithwaite I, Beasley R. Pharmacy Research Network. Protocol for a randomised controlled trial of 90% kanuka honey versus 5% aciclovir for the treatment of herpes simplex labialis in the community setting. BMJ Open 2017; 7: e017766.

42. Semprini R, Caswell-Smith R, Fingleton J, Holweg C, Matthews J, Weatherall M, Beasley R, Braithwaite I on behalf of the Periostin Study Team. Longitudinal variation of serum periostin levels in adults with stable asthma. J Allergy Clin Immunol 2017; 139: 1687-8.

43. Skrifvars MB, Bailey M, French C, Presneill J, Nichol A, Little L, Duranteau J, Huet O, Haddad S, Arabi Y, McArthur C, Cooper DJ, Bellomo R; EPO-TBI investigators and the ANZICS Clinical Trials Group. Erythropoietin in patients with traumatic brain injury and extracranial injury-A post hoc analysis of the erythropoietin traumatic brain injury trial. J Trauma Acute Care Surg 2017; 83: 449-56.

44. Skrifvars MB, Bailey M, Presneill J, French C, Nichol A, Little L, Durantea J, Huet O, Haddad S, Arabi Y, McArthur C, Cooper DJ, Bellomo R; EPO-TBI investigators and the ANZICS Clinical Trials Group. Venous thromboembolic events in critically ill traumatic brain injury patients. Intensive Care Med 2017; 43: 419-28.

45. Skrifvars MB, French C, Bailey M, Presneill J, Nichol A, Little L, Durantea J, Huet O, Haddad S, Arabi Y, McArthur C, Cooper DJ, Bellomo R. Cause and timing of death and subgroup differential effects of erythropoietin in the EPO-TBI study. J Neurotrauma 2018; 35: 33340.

46. Thomas R, Fysh ETH, Smith NA, Lee P, Kwan BCH, Yap E, Horwood FC, Piccolo F, Lam DCL, Garske LA, Shrestha R, Kosky C, Read CA, Murray K, Lee YCG. Effect of an indwelling pleural catheter vs talc pleurodesis on hospitalization days in patients with malignant pleural effusion: The AMPLE Randomized Clinical Trial. JAMA 2017; 318: 1903-12.

47. Thorne K, McNaughton H, Weatherall M. An audit of coagulation screening in patients presenting to the emergency department for potential stoke thrombolysis. Int Med J 2017; 47: 189-93.

48. Udy AA, Dulhunty JM, Roberts JA, Davis JS, Webb SAR, Bellomo R, Gomersall C, Shirwadkar C, Eastwood GM, Myburgh J, Paterson DL, Starr T, Paul SK, Lipman J, The BLING II Investigators, The ANZICS Clinical Trials Group. Association between augmented renal clearance and clinical outcomes in patients receiving beta-lactam antibiotic therapy by continuous or intermittent infusion: a nested cohort study of the BLING-II randomised, placebo-controlled, clinical trial. International journal of antimicrobial agents 2017; 49: 624-30.

49. Young PJ, Bailey MJ, Beasley RW, Freebairn RC, Hammond NE, Haren FM, Harward ML, Henderson SJ, Mackle DM, McArthur CJ, McGuinness SP, Myburgh JA, Saxena MK, Turner A, Webb SA, Bellomo R; The ANZICS Clinical Trials Group. Protocol and statistical analysis plan for the Randomised Evaluation of Active Control of Temperature versus Ordinary Temperature Management (REACTOR) trial. Crit Car Resus 2017; 19: 81-7.

50. Young PJ, Mackle DM, Bailey MJ, Beasley RW, Bennett VL, Deane AM, Eastwood GM, Finfer S, Freebairn RC, Litton E, Linke NJ, McArthur CJ, McGuinness SP, Panwar R, Bellomo R, ICU-ROX pilot investigators, and the ANZICS CTG. Intensive Care Unit Randomized trial comparing two approaches to OXygen therapy (ICU-ROX): results of the pilot phase. Crit Care Resusc 2017; 19: 344-54.

51. Young P, Ritzema J. Admitting elderly patients to ICU: is it just about survival? NZMJ 2017; 130: 1453.

52. Young PJ, Saxena M, Nielsen N. Fever control. Intensive Care Med 2017; Epub 22 October, DOI:10.1007/s00134-017-4969-8.

2016

1. Agusti A, Bel E, Thomas M, Vogelmeier C, Brusselle G, Holgate S, Humbert M, Jones P, Gibson PG, Vestbo J, Beasley R, Pavord ID. Treatable traits: toward precision medicine of chronic airway diseases. Eur Respir J 2016; 47: 410-9.

2. Beasley R, Hancox R, Harwood M, Perrin K, Poot B, Pilcher J, Reid J, Talemaitoga A, Thayabaran D. Asthma and Respiratory Foundation NZ Adult Asthma Guidelines: a Quick Reference Guide. NZ Med J 2016; 129: 83102.

3. Beasley R, Pavord I, Papi A, Reddel HK, Harrison T, Marks GB, Hancox RJ, Weatherall M. Description of a randomised controlled trial of inhaled corticosteroid/fast-onset LABA reliever therapy in mild asthma. Eur Respir J 2016; 47: 981-4.

4. Bellomo R, Landoni G, Young P. Improved survival in critically ill patients: are large RCTs more useful than personalized medicine? Yes. Intensive Care Med 2016; Sep 12. [Epub ahead of print]

5. Bibby S, Reddy S, Cripps T, McKinstry S, Weatherall M, Beasley R, Pilcher J. Tolerability of nasal delivery of humidified and warmed air at different temperatures: a randomised double-blind pilot study. Pulm Med 2016: 2016: 7951272.

6. Braithwaite I, De Ruyter B, Semprini A, Ebmeier S, Kiddle G, Willis N, Carter J, Weatherall M, Beasley R. Cohort feasibility study of an intermittent pneumatic compression device within a below-knee cast for the prevention of venous thromboembolism. BMJ Open 2016; 6: e012764.

7. Braithwaite I, Dunbar L, Eathorne A, Weatherall M, Beasley R. Venous thromboembolism rates in lower limb immobilization after Achilles tendon injury unchanged after introduction of prophylactic aspirin: audit. J Thromb Haemost 2016; 14: 3315.

8. Braithwaite I, Healy B, Cameron L, Weatherall M, Beasley R. Venous thromboembolism risk associated with protracted work- and computer-related seated immobility: a case-control study. JRSM Open 2016; 7(8): 1-8.

9. Braithwaite I, Mackintosh S, Mallon A, Weatherall M, Beasley R. Legflow® increases lower-limb venous haemodynamics when seated: a randomised controlled trial. Occupational Ergonomics 2016; 12: 131-40.

10. Braithwaite I, Shirtcliffe P, Weatherall M, Beasley R. Anti-androgen contraceptive pills and higher risk of venous thromboembolism. NZ Med J 2016; 129; 102-4.

11. Braithwaite I, Williams M, Power S, Pilcher J, Weatherall M, Baines A, Moynihan J, Kempsford R, Beasley R on behalf of FF/ VI Study Team. Randomised, double-blind, placebo-controlled, cross-over single dose study of the bronchodilator duration of action of combination fluticasone furoate/vilanterol inhaler in adult asthma. Respir Med 2016; 119: 115-21.

12. Brown SGA, Ball EL, Perrin K, Read CA, Asha SE, Beasley R, Egerton-Warbuton D, Jones PG, Keijzers G, Kinnear FB, Kwan BCH, Lee YCG, Smith JA, Summers QA, Simpson G, the PSP Study Group. Study protocol for a randomised controlled trial of invasive versus conservative management of primary spontaneous pneumothorax. BMJ Open 2016; 6: e011826.

13. Casamento A, Minson A, Radford S, Martensson J, Ridgeon E, Young P, Bellomo R. A comparison of therapeutic hypothermia and strict therapeutic normothermia after cardiac arrest. Resuscitation 2016; 106: 83-8.

14. Caswell-Smith R, Hosking A, Cripps T, Holweg C, Matthews J, Holliday M, Maillot C, Fingleton J, Weatherall M, Braithwaite I, Beasley R. Reference ranges for serum periostin in a population without asthma or chronic obstructive pulmonary disease. Clin Exp Allergy 2016; 46: 1303-14.

15. Easther S, Langdana F, Maharaj D, Abels P, Beasley R, Entwisle J. The diagnostic role of ventilation/ perfusion scans versus computed tomography pulmonary angiography in obstetric patients investigated for pulmonary embolism at Wellington Hospital from 2010 to 2012. NZMJ 2016; 129: 62-8.

16. Eastwood GM, Schneider AG, Suzuki S, Peck L, Young H, Tanaka A, Martensson J, Warrillow S, McGuinness S, Parke R, Gilder E, McCarthy L, Galt P, Taori G, Eliott S, Lamac T, Bailey M, Harley N, Barge D, Hodgson CL, Morganti-Kossmann MC, Pebay A, Conquest A, Archer JS, Bernard S, Stub D, Hart GK, Bellomo R. Targeted therapeutic mild hypercapnia after cardiac arrest: A phase II multi-centre randomised controlled trial (the CCC trial). Resuscitation 2016;104: 83-90.

17. Fanning N, Galvin S, Parke R, Gilroy J, Bellomo R, McGuinness S. A Prospective Study of the Timing and Accuracy of Neutrophil Gelatinase-Associated Lipocalin Levels in Predicting Acute Kidney Injury in High-Risk Cardiac Surgery Patients. J Cardiothorac Vasc Anesth 2016;30: 76-81.

18. Fingleton J, Braithwaite I, Travers J, Bowles D, Strik R, Siebers R, Holweg C, Matthews J, Weatherall M, Beasley R. Serum periostin in obstructive airways disease. Eur Respir J 2016; 47: 1383-91.

19. Hodgson C, Bellomo R, Bailey M, Berney S, Denehy L, Gabbe B, Harrold M, Higgins A, Iwashyna T, Papworth R, Parke R, Patman S, Presneill J, Saxena M, Skinner E, Tipping C, Young P, Webb S, The Trial of Early Activity and Mobilization (TEAM) investigators, and the ANZICS Clinical Trials Group. A bi-national, multi-center, pilot, feasibility RCT of early goaldirected mobilization in ICU. Crit Care Med 2016; 44: 1145-52.

20. ICU DECLARE investigators (Young P, corresponding author). Validation of a classification system for causes of death in critical care: an assessment of inter-rater reliability. Crit Care Resusc 2016; 18: 50-4.

21. Jefferies S, Braithwaite I, Walker S, Weatherall M, Jennings L, Luck M, Barrett K, Siebers R, Blackmore T, Beasley R, Perrin K, Pi Study Group. Randomized controlled trial of the effect of regular paracetamol on influenza infection. Respirology 2016; 21: 370-7.

22. Kansal A, Chatterjee S, Rana MH, Lee Y, Freebairn R. Is my patient really brain dead? Crit Care Shock 2016; 19: 83-5.

23. McGuinness SP, Parke RL, Drummond K, Willcox T, Bailey M, Kruger C, Baker M, Cowdrey KA, Gilder E, McCarthy L, Painter T. A multicenter, randomized, controlled phase IIb trial of avoidance of hyperoxemia during cardiopulmonary bypass. Anesthesiology 2016; 125: 465-73.

24. McNaughton A, Aldington S, Williams G, Levack WMM. Sing Your Lungs Out: a qualitative study of a community singing group for people with chronic obstructive pulmonary disease (COPD). BMJ Open 2016; 6: e012521.

25. McNaughton A, Blackmore T, McNaughton H. Comprehensive cost of treating one patient with MDR/pre-XDR-TB in Wellington, New Zealand. Eur Respir J 2016; 48: 1256-9.

26. McNaughton AA, Weatherall M, Williams G, Delacey D, George C, Beasley R. An audit of pulmonary rehabilitation program. Clin Audit 2016; 8: 7-12.

27. O’Connor P, Judson G, Loan RA, Robinson G. Prevalence of hepatitis C among injecting drug users attending clinics. NZMJ 2016; 129: 44-8.

28. Pacheco-Gonzalez R, Ellwood E, Exeter D, Stewart AW, Asher I. Does urban extent from satellite images relate to symptoms of asthma, rhinoconjunctivitis and eczema in children? A cross-sectional study from ISAAC Phase Three. J Asthma 2016; 53: 854-61.

29. Panwar R, Hardie M, Bellomo R, Barrot L, Eastwood GM, Young PJ, Capellier G, Harrigan PW, Bailey M, for the CLOSE Study investigators and the ANZICS Clinical Trials Group. Conservative versus liberal oxygenation targets for mechanically ventilated patients: a pilot multicenter randomized controlled trial. Am J Respir Crit Care Med 2016; 193: 43-51.

30. Pilcher J, Holliday M, Ebmeier S, McKinstry S, Messaoudi F, Weatherall M, Beasley R. Validation of a metered dose inhaler electronic monitoring device: implications for asthma clinical trial use. BMJ Open Respiratory Research 2016; 3(1) e000128.

31. Pilcher J, Patel M, Reddel H, Pritchard A, Black P, Shaw D, Holt S, Weatherall M, Beasley R. The effect of smoking status on the efficacy of the SMART regimen in high risk asthma. Respirology 2016; 21: 858-66.

32. Reade MC, Eastwood GM, Bellomo R, Bailey M, Bersten A, Cheung B, Davies A, Delaney A, Ghosh A, van Haren F, Harley N, Knight D, McGuiness S, Mulder J, O’Donoghue S, Simpson N, Young P. Effect of dexmedetomidine added to standard care on ventilator-free time in patients with agitated delirium: a randomized clinical trial. JAMA 2016; 315: 1460-8.

33. Reddy S, Bailey M, Beasley R, Bellomo R, Mackle D, Psirides A, Young P. Effect of saline 0.9% or Plasma-Lyte 148 therapy on feeding intolerance in patients receiving nasogastric enteral nutrition. Crit Care Resusc 2016;18(3):198-204.

34. Reddy S, McGuinness S, Parke R, Young P. Choice of fluid therapy and bleeding risk after cardiac surgery. J Cardiothorac Vasc Anesth 2016;30: 1094-103.Ridgeon EE, Young PJ, Bellomo R, Mucchetti M, Lembo R, Landoni G. The Fragility Index in Multicenter Randomized Controlled Critical Care Trials. Crit Care Med 2016; 44: 1278-84.

35. Reddy S, Weinberg L, Young P. Crystalloid fluid therapy. Crit Care 2016;20: 59.

36. Ridgeon EE, Young PJ, Bellomo R, Mucchetti M, Lembo R, Landoni G. The authors reply. Crit Care Med 2016;44: e1143.

37. Ridgeon EE, Young PJ, Bellomo R, Mucchetti M, Lembo R, Landoni G. The Fragility Index in multicenter randomized controlled critical care trials. Crit Care Med 2016; 44: 12784.

38. Riley J, Hunt A, McDouall A, Waqanivavalagi S, Braithwaite I, Weatherall M, Stanley T, Beasley R, Mitchell EA, Dalziel SR. Pilot study of feasibility of a randomised controlled trial of asthma risk with paracetamol versus ibuprofen use in infancy. NZ Med J 2015; 129: 30-42.

39. Semprini A, Braithwaite I, Corin A, Sheahan D, Tofield C, Montgomery B, Fingleton J, Weatherall M, Beasley R. Randomised controlled trial of topical kanuka honey for the treatment of acne. BMJ Open 2016; 6: e009448.

40. Tipping CJ, Bailey MJ, Bellomo R, Berney S, Buhr H, Denehy L, Harrold M, Holland A, Higgins AM, Iwashyna TJ, Needham D, Presneill J, Saxena M, Skinner EH, Webb S, Young P, Zanni J, Hodgson CL. The ICU mobility scale has construct and predictive validity and is responsive. a multicenter observational study. Ann Am Thorac Soc 2016;13: 887-93.

41. Van Der Meeren O, Peterson JT, Dionne M, Beasley R, Ebeling PR, Ferguson M, Nissen MD, Rheault P, Simpson RW, De Ridder M, Crasta PD, Miller JM, Trofa AF. Prospective clinical trial of hepatitis B vaccination in adults with and without type-2 diabetes mellitus. Hum Vaccin Immunother 2016; 12: 2197-203.

42. Venkatesh B, Corke C, Raper R, Pinder M, Stephens D, Joynt G, Morley P, Bellomo R, Bevan R, Freebairn R, Varghese B, Ashbolt M, Hawker F, Jacobe S, Yong S. Findings of the bullying, discrimination and sexual harassment survey: Response of the College of Intensive Care Medicine. Crit Care Resusc 2016; 18: 228-9.

43. Venkatesh B, Corke C, Raper R, Pinder M, Stephens D, Joynt G, Morley P, Bellomo R, Bevan R, Freebairn R, Varghese B, Ashbolt M, Hawker F, Jacobe S, Yong S. Prevalence of bullying, discrimination and sexual harassment among trainees and fellows of the College of Intensive Care Medicine of Australia and New Zealand. Crit Care Resusc 2016; 18: 230-4.

44. Young P, Bailey M, Bellomo R. Acute kidney injury with buffered crystalloids vs saline among ICU patients — Reply. JAMA 2016; 315: 1521.

45. Young P, Bellomo R, Landoni G. Timing of initiation of renal replacement therapy in critically ill patients with acute kidney injury [Correspondence]. JAMA 2016; 316(11): 12131214.

46. Young P, Machado F, Finfer S. What’s new on balanced crystalloid solutions? Intensive Care Med. 2016. Online first. DOI 10.1007/s00134-016-4498-x.

47. Young P, Saxena M, Beasley R. Acetaminophen for fever in critically ill patients with suspected infection. N Engl J Med 2016; 374: 1292-1293.

48. Young P. Acetaminophen to treat fever in ICU patients with likely infection. J Thorac Dis 2016; 8: E631-2.

49. Young P. Saline Is the solution for crystalloid resuscitation. Crit Care Med 2016; 44: 1538-1540.

1. Beasley R, Braithwaite I, Evans R. Upper extremity deep vein thrombosis in a TV cameraman. Occupat Med 2015; 65: 337-9.

2. Beasley R, Chien J, Douglas J, Eastlake L, Farah C, King, G, Moore R, Pilcher J, Richards M, Smith S, Walters H. Thoracic Society of Australia and New Zealand oxygen guidelines for acute oxygen use in adults: ‘Swimming between the flags’. Respirol 2015; 20: 1182-91.

3. Beasley RW, Donohue JF, Mehta R, Nelson HS, Clay M, Moton A, Kim H-J, Hederer BM. Effect of once-daily indacaterol maleate/ mometasone furoate on exacerbation risk in adolescent and adult asthma: a double-blind randomised controlled trial. BMJ Open 2015; 5: e006131.

4. Beasley R, Semprini A, Mitchell EA. Risk factors for asthma: is prevention possible? Lancet 2015; 386: 1075-85.

5. Bibby S, Milne R, Beasley R. Hospital admissions for non-cystic bronchiectasis in New Zealand. NZMJ 2015; 128: 30-8.

6. Braithwaite I, Hunt A, Riley J, Fingleton J, Kocks J, Corin A, Helm C, Sheahan D, Tofield C, Montgomery B, Holliday M, Weatherall M, Beasley R. Randomised controlled trial of topical kanuka honey for the treatment of rosacea. BMJ Open 2015; 5(6): e007651.

7. Braithwaite I, Stewart AW, Hancox RJ, Beasley R, Murphy R, Mitchell EA, ISAAC Phase Three Study Group. Maternal post-natal tobacco use and current parental tobacco use is associated with higher body mass index in children and adolescents: an international cross-sectional study. BMC Pediatrics 2015; 15: 220.

8. Chapman M, Young PJ, Peake S. Permissive Underfeeding or Standard Enteral Feeding in Critical Illness [Correspondence]. N Engl J Med 2015; 373:1173-1176. September 17, 2015; DOI: 10.1056/NEJMc1509259.

9. Dulhunty JM, Roberts JA, Davis JS, Webb SA, Bellomo R, Gomersall C, Shirwadkar C, Eastwood GM, Myburgh J, Paterson DL, Starr T, Paul SK, Lipman J for the BLING II Investigators for the ANZICS Clinical Trials Group. A Multicenter Randomized Trial of Continuous versus Intermittent beta-Lactam Infusion in Severe Sepsis. Am J Respir Crit Care Med 2015; 192: 1298-305.

10. Fingleton J, Travers J, Williams M, Charles T, Bowles D, Strik R, Shirtcliffe

P, Weatherall M, Beasley R. Treatment responsiveness of phenotypes of symptomatic airways obstruction in adults. J Allergy Clin Immunol 2015: 136: 601-9.

11. Hancox RJ, Stewart AW, Braithwaite I, Beasley R, Murphy R, Mitchell EA and ISAAC Phase Three Study Group. Association between breastfeeding and body mass index at age 6-7 years in an international survey. Pediatr Obesity 2015; 10: 283-7.

12. Hodgson CL, Bellomo R, Berney S, Baiey M, Buhr H, Denehy L, Harrold M, Higgins M, Higgins A, Presneill J, Saxena M, Skinner E, Webb S, Young P. Early mobilization and recovery in mechanically ventilated patients in ICU. Crit Care 2015; 19: 81.

13. Holt S, Patel M, Montgomery B, Weatherall M, Beasley R. Cohort study of a simple ‘Step-Up’ regimen with the Asthma Control Test. Respirology 2015; 20: 504-6.

14. Ioannides SJ, Siebers R, Perrin K, Weatherall M, Crane J, Travers J, Shirtcliffe P, Beasley R. The effect of 1g of acetaminophen twice daily for 12 weeks on alanine transaminase levels — A randomized placebocontrolled trial. Clin Biochem 2015; 48: 713-5.

15. Krag M, Perner A, Wetterslev J, Wise MP, Borthwick M, Bendel S, McArthur C, Cook D, Nielsen N, Pelosi P, Keus F, Guttormsen AB, Moller AD, Møller MH; SUP-ICU Collaborators. Stress ulcer prophylaxis in the intensive care unit: an international survey of 97 units in 11 countries. Acta Anaesthesiol Scand. 2015;59(5):576-85.

16. Krag M, Perner A, Wetterslev J, Wise MP, Borthwick M, Bendel S, McArthur C, Cook D, Nielsen N, Pelosi P, Keus F, Guttormsen AB, Moller AD, Møller MH; SUP-ICU co-authors. Prevalence and outcome of gastrointestinal bleeding and use of acid suppressants in acutely ill adult intensive care patients. Intensive Care Med. 2015; 41: 833-45.

17. McGuinness S, Parke R. Using cardiac output monitoring to guide perioperative haemodynamic therapy. Curr Opin Crit Care 2015; 21: 364-8.

18. Milne RJ, Beasley R. Hospital admissions for chronic obstructive pulmonary disease in New Zealand. NZMJ 2015; 128: 23-35.

19. Murphy R, Stewart AW, Braithwaite I, Beasley R, Hancox RJ, Mitchell EA, and the ISAAC Phase Three Study Group. Association between paracetamol use in infancy or childhood with body mass index. Obesity 2015; 23: 1030-8.

20. Parke RL, Bloch A, McGuinness SP. Effect of Very-High-Flow Nasal Therapy on Airway Pressure and End-Expiratory Lung Impedance in Healthy Volunteers. Respir Care 2015; 60: 1397-403.

21. Parke RL, McGuinness SP, Gilder E, McCarthy LW, Cowdrey KA. A randomised feasibility study to assess a novel strategy to rationalise fluid in patients after cardiac surgery. Br J Anaesth 2015; 115: 45-52.

22. Patel M, Pilcher J, Hancox RJ, Sheahan D, Pritchard A, Braithwaite I, Shaw D, Black P, Weatherall M, Beasley R. The use of ß2-agonist therapy before hospital attendance for severe asthma exacerbations: a post-hoc analysis. NPJ Prim Care Respir J 2015; 25: 14099.

23. Peake SL, Young PJ, Chapman M, TARGET investigators. Permissive underfeeding or standard enteral feeding in critical illness. N Engl J Med 2015; 373: 1173-4.

24. Pilcher J, Beasley R. Acute use of oxygen therapy. Aust Prescr 2015; 38: 98-100.

25. Pilcher J, Cameron L, Braithwaite I, Bowles D, Swain A, Bailey M, Weatherall M, Beasley R, Perrin K. Comparative audit of oxygen use in the prehospital setting, in acute COPD exacerbation, over 5 years. Emerg Med J 2015; 32: 234-8.

26. Pilcher J, Shirtcliffe P, Patel M, McKinstry S, Cripps T, Weatherall M, Beasley R. Three-month validation of a turbuhaler electronic monitoring device: implications for asthma clinical trial use. BMJ Open Resp Res 2015; 2: e000097 doi:10.1136/ bmjresp-2015-000097.

27. Pilcher J, Weatherall M, Perrin K, Beasley R. Oxygen therapy in acute exacerbations of chronic obstructive pulmonary disease. Expert Rev Respir Med 2015; 9: 287-93.

28. Reddy S, Beasley R, Mackle D, McGuinness S, McArthur C, Henderson S, Weinberg L, French C, Orford N, Bailey M, Bellomo R, Young P, the SPLIT investigators, and the ANZICS CTG investigators. An overview of the study protocols and statistical analysis plan for the Saline vs. Plasma-Lyte 148® for Intravenous Fluid Therapy (SPLIT) research program. Crit Care Resusc. 2015 Mar; 17: 29-36.

29. Reddy SK, Young PJ, Beasley RW, Mackle DM, McGuinness SP, McArthur CJ, Henderson SJ, Weinberg L, French CJ, Orford NR, Bailey MJ, Bellomo R, the SPLIT investigators, and the ANZICS CTG investigators. Overview of the study protocols and statistical analysis plan for the Saline versus Plasma-Lyte 148® for Intravenous Fluid Therapy (SPLIT) research program. Crit Care Resusc 2015; 17: 29-36.

30. Ridley EJ, Davies AR, Parke R, Bailey M, McArthur C, Gillanders L, Cooper DJ, McGuinness S, and the Supplemental Parenteral Nutrition Clinical Investigators. Supplemental parenteral nutrition in critically ill patients: a study protocol for a phase II randomised controlled trial. Trials. 2015; 16: 587. Published online 2015 Dec 24. doi: 10.1186/s13063-0151118-y.

31. Riley J, Braithwaite I, Shirtcliffe P, Caswell-Smith R, Hunt A, Bowden V, Power S, Stanley T, Crane J, Ingham T, Weatherall M, Mitchell EA, Beasley R. Randomized controlled trial of asthma risk with paracetamol in infancy – a feasibility study. Clin Exp Allergy 2015; 45: 448-56.

32. Saxena M, Young P, Pilcher D, Bailey M, Harrison D, Bellomo R, Finfer S, Beasley R, Hyam J, Menon D, Rowan K, Myburgh J. Early temperature and mortality in critically ill patients with acute neurological diseases: trauma and stroke differ from infection. Intensive Care Med 2015; 41: 823-32.

33. Saxena MK, Taylor C, Hammond N, Young P, Mysore J, Billot L, Myburgh A, Myburgh J. A multi-centre audit of temperature patterns after traumatic brain injury. Crit Care Resusc 2015 Jun; 17: 129-134.

34. Semprini A, Fingleton J, Hunt A, Riley J, Corin A, Tofield C. A single-blind randomised controlled trial of topical kanuka honey for the treatment of nappy rash. FACT 2015; 20: 187-8.

35. Strachan DP, Aït-Khaled N, Foliaki S, Mallol J, Odhiambo J, Pearce N, Williams HC, the ISAAC Phase Three Study Group. Siblings, asthma, rhinoconjunctivitis and eczema: a worldwide perspective from the International Study of Asthma and Allergies in Childhood. Clin Exper Allergy 2015; 45: 126-36.

36. Walker L, Young P. Fluid administration, vasopressor use and patient outcomes in a group of high-risk cardiac surgical patients receiving postoperative goal directed haemodynamic therapy: a pilot study. Anaesthesia and Intensive Care. 2015; 2015 Sep;43(5):617-27.

37. Weatherall M, Ioannides S, Braithwaite I, Beasley R. The association between paracetamol use and asthma: causation or coincidence? Clin Exper Allergy 2015; 45: 108-13.

38. Weinkove R, Bailey M, Bellomo R, Saxena MK, Tam CS, Pilcher DV, Beasley R, Young PJ. Association between early peak temperature and mortality in neutropenic sepsis. Ann Hematology 2015; 94: 857-64.

39. Young P. The illusion of physiological gain and the rise of less is more. Intensive Care Monitor. 2015; 22(3): 42.

40. Young PJ, Bailey M, Beasley R, Henderson S, Mackle D, McArthur C, Mehrtens J, Myburgh J, McGuinness S, Psirides A, Reddy S, Bellomo R and for the SPLIT investigators and the ANZICS CTG. Effect of a buffered crystalloid solution vs. saline on acute kidney injury among patients in the Intensive Care Unit: the SPLIT randomized clinical trial. JAMA 2015; 314: 170110.

41. Young PJ, Beasley RW, Capellier G, Eastwood GM, Webb SAR. Oxygenation targets and monitoring in the critically ill: a point prevalence study of clinical practice in Australia and New Zealand. Crit Care Resusc 2015; 17 202-7.

42. Young PJ, Saxena M, Bellomo R, Freebairn R, Hammond N, van Haren F, Holliday M, Henderson S, Mackle D, McArthur C, McGuinness S, Myburgh J, Weatherall M, Webb S, Beasley R for the HEAT investigators and the ANZICS CTG. Acetaminophen for fever in critically ill patients with suspected infection. N Engl J Med 2015; 373: 2215-24.

2014

1. Beasley R, Weatherall M, Shirtcliffe P, Hancox R, Reddel HK. Combination corticosteroid/ beta-agonist inhaler as reliever therapy: a solution for intermittent and mild asthma? J Allergy Clin Immunol 2014; 133: 39-41.

2. Beasley R. Cannabis and the lung. New Zealand Centre for Political Research, November 9, 2014.

3. Braithwaite I, Maxwell G, Sparks S, Beasley R, Shirtcliffe P. A man who collapsed after using the internet. JRSM Open 2014;5: 2054270414543397.

4. Braithwaite I, Stewart AW, Hancox RJ, Beasley R, Murphy R, Mitchell EA, the ISAAC Phase Three Study Group. Fast-food consumption and body mass index in children and adolescents: an international crosssectional study. BMJ Open 2014; 4: e005813.

5. Eastwood GM, Litton E, Bellomo R, Bailey MJ, Festa M, Beasley RW, Young PJ. Opinions and practice of stress ulcer prophylaxis in Australian and New Zealand intensive care units. Crit Care Resusc 2014; 16: 170-4.

6. Eastwood GM, Young PJ, Bellomo R. The impact of oxygen and carbon dioxide management on outcome after cardiac arrest. Curr Opin Crit Care 2014; 20: 266-72.

7. Fingleton J, Corin A, Sheahan D, Cave N, Braithwaite I, Weatherall M, Beasley R. Randomised controlled trial of topical kanuka honey for the treatment of cold sores. Adv Integrat Med 2014; 1: 119-23.

8. Fingleton J, Helm C, Tofield C, Weatherall M, Beasley R. A randomised controlled trial of topical Kanuka honey for the treatment of eczema. JRSM Open 2014; 5(1): 2042533313509263.

9. Fingleton J, Sheahan D, Corin A, Weatherall M, Beasley R. A randomised controlled trial of topical Kanuka honey for the treatment of psoriasis. JRSM Open 2014; 5(3): 2042533313518913.

10. Fingleton J, Tofield C, Helm C, Corin A, Weatherall M, Beasley R. Topical kanuka honey for the treatment of nappy rash. FACT 2014; DOI 10.1111/fct.12078.

11. Fysh ETH, Thomas R, Read CA, Lam BCH, Yap E, Horwood FC, Lee P, Piccolo F, Shrestha R, Garske LA, Lam DCL, Rosenstengel A, Bint M, Murray K, Smith NA, Lee YCG. Protocol of the Australasian Malignant Pleural Effusion (AMPLE) trial: a multicentre randomised study comparing indwelling pleural catheter versus talc pleurodesis. BMJ Open 2014; 4: e006757.

12. Hansell A, Ghosh RE, Poole S, Zock JP, Weatherall M, Vermeulen R, Kromhout H, Travers J, Beasley R. Occupational risk factors for chronic obstructive respiratory disease in a New Zealand population using lifetime occupational history. J Occup Environ Med 2014; 56: 270-80.

13. Hodgson C, Needham D, Haines K, Bailey M, Ward A, Harrold M, Young P, Zanni J, Buhr H, Higgins A, Presneill J, Berney S. Feasibility and inter-rater reliability of the ICU Mobility Scale. Heart & Lung 2014; 43: 19-24.

14. Hodgson CL, Stiller K, Needham DM, Tipping CJ, Harrold M, Baldwin CE, Bradley S, Berney S, Caruana LR, Elliott D, Green M, Haines K, Higgins AM, Kaukonen KM, Leditschke I, Nickels MR, Paratz J, Patman S, Skinner EH,

Young PJ, Zanni JM, Denehy L, Webb SA. Expert consensus and recommendations on safety criteria for active mobilization of mechanically ventilated critically ill adults. Crit Care 2014; 18: 658.

15. Holt S, Sheahan D, Helm C, Tofield C, Corin A, Kocks JWH. Little agreement in GOLD category using CAT and mMRC in 450 primary care COPD patients in New Zealand. Prim Care Respir Med 2014; 24: 14025 doi:10.1038/ npjpcrm.2014.25.

16. Ioannides SJ, Williams M, Jefferies S, Perrin K, Weatherall M, Siebers R, Crane J, Patel M, Travers J, Shirtcliffe P, Beasley R. Randomised placebo-controlled study of the effect of paracetamol on asthma severity in adults. BMJ Open 2014; 4: e004324.

17. Levack WMM, Poot B, Weatherall M, Travers J. Interventions for sexual dysfunction in people with chronic obstructive pulmonary disease (COPD). Cochrane Database of Systematic Reviews 2014; (Issue 12) CD011442. DOI: 10.1002/14651858.CD011442.

18. Litton E, Bellomo R, Beasley R, Bailey MJ, Forbes AB, Gattas DJ, Pilcher DV, Webb SAR, McGuinness SP, Saxena MK, McArthur CJ, Young PJ, on behalf of the PEPTIC investigators. A multicentre feasibility study evaluating stress ulcer prophylaxis using hospital-based registry data. Crit Care Resus 2014; 16: 158-63.

19. Litton E, Eastwood GM, Bellomo R, Beasley R, Bailey MJ, Forbes AB, Gattas DJ, Pilcher DV, Webb SA, McGuinness SP, Saxena MK, McArthur CJ, Young PJ. A multicentre feasibility study evaluating stress ulcer prophylaxis using hospital-based registry data. Crit Care Resusc 2014; 16: 158-63.

20. Manning S, Gilmour M, Weatherall M, Robinson GM. Refeeding syndrome is uncommon in alcoholics admitted to a hospital detoxification unit. Intern Med J 2014; 44: 512-4.

21. McNaughton H, McRae A, Green G, Abernethy G, Gommans J. Stroke rehabilitation services in New Zealand: a survey of service configuration, capacity and guideline adherence. NZ Med J 2014; 127: 9-10.

22. McNaughton H, Thompson S, Stinear C, Harwood M, McPherson KM. Optimizing the content and dose of rehabilitation in the first 12 months following stroke. Crit Rev Physical Rehab Med 2014; 26: 27-50.

23. Mitchell EA, Clayton T, Garcia-Marcos L, Pearce N, Foliaki S, Wong G. Birthweight and the risk of atopic diseases: the ISAAC Phase III study. Pediatr Allergy Immunol 2014;25: 264-70.

24. Murphy R, Stewart AW, Braithwaite I, Beasley R, Hancox RJ, Mitchell EA, ISAAC Phase Three Study Group. Antibiotic treatment during infancy and increased body mass index in boys: an international cross-sectional study. Int J Obesity 2014; 38: 1115-9.

25. Nazmi A, Weatherall M, Wilkins B, Robinson GM. Thiamin concentration in geriatric hospitalized patients using frusemide. J Nutr Gerontol Geriatr 2014; 33: 47-54.

26. Newberry J, Wodak A, Sellman D, Robinson G. New Zealand’s regulation of new psychoactive substances: a response to the futility of trying to ban such substances as they appear. BMJ 2014; 348: g1534.

27. Patel M, Pilcher J, Reddel HK, Qi V, Mackey B, Tranquilino T, Shaw D, Black P, Weatherall M, Beasley R for the SMART Study Group. Predictors of severe exacerbations, poor asthma control, and ß-agonist overuse in asthma for patients with asthma. J Allergy Clin Immunol: In Pract 2014; 2: 751-8.

28. Piccolo F, Pitman N, Bhatnagar R, Popowicz N, Smith NA, Brockway B, Nickels R, Burke AJ, Wong CA, McCartney R, Choo-Kang B, Blyth KG, Maskell NA, Lee YC. Intrapleural tPA and DNase for Pleural Infection: an effective and safe alternative to surgery. Ann Am Thorac Soc 2014; 11: 1419-25.

29. Pilcher J, Patel M, Smith A, Davies C, Pritchard A, Travers J, Black P, Weatherall M, Beasley R, Harwood M. Combination budesonide/formoterol inhaler as maintenance and reliever therapy in Māori with asthma. Respirol 2014; 19: 842-51.

30. Reddy SK, Bailey MJ, Beasley RW, Bellomo R, Henderson SJ, Mackle DM, McArthur CJ, Mehrtens JE, Myburgh JA, McGuinness SP, Psirides AJ, Young PJ, and the ANZICS Clinical Trials Group. A protocol for the 0.9% saline versus Plasma-Lyte 148 for intensive care fluid therapy (SPLIT) study. Crit Care Resus 2014; 16: 274-9.

31. Reddy S, Wang N, Weatherall M, Mahon B, Young P. A pre-printed medication chart in the ICU for patients admitted after coronary artery bypass graft surgery improves prescribing of secondary prevention at hospital discharge. Crit Care & Shock 2014; 3: 61-5.

32. Tan PC, Robinson G, Jayathissa S, Weatherall M. Coming to work sick: a survey of hospital doctors in New Zealand. NZ Med J 2014; 127: 23-35.

33. Tan PC, Robinson G, Jayathissa S, Weatherall M. Coming to work sick: a survey of hospital doctors in New Zealand. NZMJ Digest 2014; 46: 31-5.

34. Walker S, Fingleton J, Weatherall M, Beasley R. Limited generalisability of UPLIFT findings to clinical practice (letter in response to Tashkin). Thorax 2014; 69: 385-6.

35. Walker S, Smith N. Should patients be advised not to fly post-thoracentesis? Respir Med Case Reports 2014; doi: 10.1016/j. rmcr.2014.06.002.

36. Young P, Bailey M, Bellomo R, Bernard S, Dicker B, Freebairn R, Henderson S, Mackle D, McArthur C, McGuinness S, Smith T, Swain A, Weatherall M, Beasley R. HyperOxic Therapy OR NormOxic Therapy after out-of-hospital cardiac arrest (HOT OR NOT): a randomised controlled feasibility trial. Resusc 2014; 85: 1686-91.

37. Young P, Bellomo R. Fever in sepsis: is it cool to be hot? Crit Care 2014; 18: 109.

38. Young P, Saxena M. Fever Management in Intensive Care Patients with Infections. Crit Care 2014; 18: 206.

39. Young PJ, Delaney AP, Dulhunty JM, Venkatesh B. Critical care statistical analysis plans. In reply. Crit Care Resusc 2014; 16: 76-7.

40. Young PJ, Joannidis M. Crystalloid fluid therapy: is the balance tipping towards balanced solutions? Intens Care Med 2014; 40: 1966-8.

2013

1. Beasley R. Tiotropium Respimat increases the risk of mortality: pro. Eur Respir J 2013; 42: 584-9 (Editorial).

2. Beasley R, Fingleton J, Weatherall M. Restriction of LABA use to combination ICS/ LABA inhaler therapy in asthma. Thorax 2013; 68: 119-20.

3. Braithwaite I, Stewart AW, Hancox RJ, Beasley R, Murphy R, Mitchell EA, ISAAC Phase Three Study Group. The worldwide association between television viewing and obesity in children and adolescents: cross sectional study. PLoS ONE 2013; 8: e74263.

4. Charles T, Mackintosh S, Fingleton J, Braithwaite I, Weatherall M, Beasley R. Efficacy of micromobile foot compression device in increasing lower limb venous blood flow. Int J Vasc Med 2013; http://dx.doi. org/10.1155/2013/948769.

5. Edwards L, Shirtcliffe P, Wadsworth K, Healy B, Jefferies S, Weatherall M, Beasley R on behalf of the Magnesium COPD Study Team. Use of nebulised magnesium sulphate as an adjuvant in the treatment of acute exacerbations of COPD in adults: a randomised double-blind placebo-controlled trial. Thorax 2013; 68: 338-43.

6. Ellwood P, Asher MI, Garcia-Marcos L, Williams H, Keil U, Robertson C, Nagal G, the ISAAC Phase II Study Group. Do fast foods cause asthma, rhinoconjunctivitis and eczema? Global findings from the International Study of Asthma and Allergies in Childhood (ISAAC) Phase Three. Thorax 2013; 68: 351-60.

7. Fernando J, Ikeda T, Psirides A, Young P. Admission source predicts delay to antimicrobial therapy in septic shock - a retrospective cohort study. Crit Care & Shock 2013; 16:37-44.

8. Fingleton J, Sheahan D, Cave N, Brinded A, Weatherall M, Perrin K, Beasley R. Topical kanuka honey for the treatment of rosacea. FACT 2013; 18: 221-2.

9. Hammond NE, Saxena MK, Taylor C, Young P, Seppelt I, Glass P, Myburgh J; George Institute for Global Health; Australian and New Zealand Intensive Care Society Clinical Trials Group. Temperature management of non-elective intensive care patients without neurological abnormalities: a point prevalence study of practice in Australia and New Zealand. Crit Care Resusc 2013; 15: 228-33.

10. Healy B, Bibby S, Steele R, Weatherall M, Nelson H, Beasley R. Antineutrophil cytoplasmic autoantibodies and myeloperoxidase autoantibodies in clinical expression of Churg-Strauss syndrome. J Allergy Clin Immunol 2013; 131: 571-6.

11. Jenkins CR, Beasley R. Tiotropium Respimat increases the risk of mortality. Thorax 2013; 68: 5-7 (Editorial).

12. Manchanda A, Cameron C, Robinson G. Beware of paracetamol use in alcohol abusers: a potential cause of acute liver injury. NZMJ 2013; 126(1383): 80-4.

13. Mitchell E, Beasley R, Björkstén B, Crane J, Garcia-Marcos L, Keil U. The association between BMI, vigorous physical activity and television viewing and the risk of symptoms of asthma, rhinoconjunctivitis and eczema in children and adolescents: ISAAC Phase Three. Clin Exper Allergy 2013; 43: 73-84.

14. Patel M, Perrin K, Pritchard A, Williams M, Wijesinghe M, Weatherall M, Beasley R. Accuracy of patient self-report as a measure of inhaled asthma medication use. Respirology 2013; 18: 546-52.

15. Patel M, Pilcher J, Beasley R. Combination ICS/fast-onset LABA inhaler as maintenance and reliever therapy: the future for uncontrolled adult asthma? Expert Rev Respir Med 2013; 7: 451-4.

16. Patel M, Pilcher J, Munro C, Hosking A, Pritchard A, Shaw D, Black P, Weatherall M, Beasley R. Short-acting ß-agonist use as a marker of current asthma control. J Allergy Clin Immunol: In Practice 2013; 1: 370-7.

17. Patel M, Pilcher J, Pritchard A, Perrin K, Travers J, Shaw D, Holt S, Harwood M, Black P, Weatherall M, Beasley R for the SMART Study Group. Efficacy and safety of maintenance and reliever combination budesonide–formoterol inhaler in patients with asthma at risk of severe exacerbations: a randomised controlled trial. Lancet Respir Med 2013; 1: 32-42.

18. Patel M, Pilcher J, Reddel HK, Pritchard A, Corin A, Helm C, Tofield C, Shaw D, Black P, Weatherall M, Beasley R and for the SMART Study Group. Metrics of salbutamol use as predictors of future adverse outcomes in asthma. Clin Exper Allergy 2013; 43: 1144-51.0.3

19. Patel M, Pilcher J, Travers J, Perrin K, Shaw D, Black P, Weatherall M, Beasley R. Use of metered-dose inhaler electronic monitoring in a real-world asthma randomized controlled trial. J Allergy Clin Immunol: In Practice 2013; 1: 83-91.

20. Patel M, Shirtcliffe P, Beasley R. The ß-2 agonist debate: is there still a problem? Curr Opin Allergy Clin Immunol 2013; 13: 58-62.

21. Pilcher J, Perrin K, Beasley R. The effect of high concentration oxygen therapy on PaCO2 in acute and chronic respiratory disorders. Translational Resp Med 2013; 1: 8-10.

22. Saxena MK, Taylor CB, Hammond NE, Young PJ, Seppelt IM, Glass P, Myburgh JA; George Institute for Global Health; ANZICS Clinical Trials Group. Temperature management in patients with acute neurological lesions: an Australian and New Zealand point prevalence study. Crit Care Resusc 2013; 15: 110-8.

23. Schneider AG, Eastwood GM, Bellomo R, Bailey M, Lipcsey M, Pilcher D, Young P, Stow P, Santamaria J, Stachowski E, Suzuki S, Woinarski NC, Pilcher J. Arterial carbon dioxide tension and outcome in patients admitted to the intensive care unit after cardiac arrest. Resuscitation 2013; 84: 927-34.

24. Weatherall M, Fingleton J, Eyers S, Beasley R. A half doubling dose change in bronchial hyperresponsiveness in a population represents an important difference. Trans Resp Med 2013; 1: 4-6.

25. Wong GWK, Brunekreef B, Ellwood P, Anderson HR, Asher MI, Crane J, Lai CKW for the ISAAC Phase Three Study Group. Cooking fuels and prevalence of asthma: a global analysis of phase three of the International Study of Asthma and Allergies in Childhood (ISAAC). Lancet Respir Med 2013; 1: 386-94.

26. Young P, Pilcher J, Patel M, Cameron L, Braithwaite I, Weatherall M, Beasley R. Delivery of titrated oxygen via a self-inflating resuscitation bag. Resuscitation 2013; 84: 391-4.

27. Young P, Weatherall M, Saxena M, Bellomo R, Freebairn R, Hammond N, van Haren F, Henderson S, McArthur C, McGuiness S, Mackle D, Myburgh J, Webb S, Beasley R and the ANZICS Clinical Trials Group. Statistical analysis plan for the HEAT trial: a multicentre randomised placebo-controlled trial of intravenous paracetamol in intensive care unit patients with fever and infection. Crit Care Resusc 2013; 15: 279-86.

28. Young PJ, Baker S, Cavazzoni E, Erickson SJ, Krishnan A, Kruger PS, Rashid AH, Wibrow BA. A case series of critically ill patients with anti- N-methyl-D-aspartate receptor encephalitis. Crit Care Resusc 2013; 15: 8-14.

29. Young PJ, Ganter DC, Nickson CP. Can Social Media Bridge the Gap between Research and Practice? Crit Care Resusc 2013; 15: 257-8.

2012

1. Brunekreef B, Von Mutius E, Wong G, Odhiambo J, Garcia-Marcos L, Foliaki S and the ISAAC Phase Three Study Group. Exposure to cats and dogs, and symptoms of asthma, rhinoconjunctivitis, and eczema. Epidemiol 2012; 23: 742-50.

2. Brunekreef B, Von Mutius E, Wong GK, Odhiambo JA, Clayton TO and the ISAAC Phase Three Study Group. Early life exposure to farm animals and symptoms of asthma, rhinoconjunctivitis and eczema: an ISAAC Phase Three Study. Int J Epidemiol 2012; 41: 753-61.

3. Cameron L, Pilcher J, Weatherall M, Beasley R, Perrin K. The risk of serious adverse outcomes associated with hypoxaemia and hyperoxaemia in acute exacerbations of COPD. Postgrad Med J 2012; doi: 10.1136/ postgradmedj-2012-130809.

4. Eastwood G, Bellomo R, Bailey M, Taori G, Pilcher D, Young P, Beasley R. Arterial oxygen tension and mortality in mechanically ventilated patients. Int Care Med 2012; 38: 91-8.

5. Eastwood PR, Naughton MT, Calverley P, Zeng G, Beasley R, Robinson B, Lee YC. APSR Postgraduate Session: How to write research papers and grants. Respirology 2012; 17: 792801.

6. Edwards L, Perrin K, Williams M, Weatherall M, Beasley R. Randomised controlled cross-over trial of the effect on PtCO2 of oxygen versus air-driven nebulisers in severe COPD. Emerg Med J 2012; 29: 894-8.

7. Ellwood P, Asher MI, Stewart AW, Ait-Khaled N, Mallol J, Strachan D and the ISAAC Phase III Time Trends Study Group. The challenges of replicating the methodology between Phases I and III of the ISAAC Programme. Int J Tuberc Lung Dis 2012; 16: 68793.

8. Eyers S J, Fingleton J, Perrin K, Beasley R. Proposed MHRA changes to UK children’s paracetamol dosing recommendations: modelling study. J R Soc Med 2012; 105: 263-9.

9. Eyers S, Fingleton J, Eastwood A, Perrin K, Beasley R. British National Formulary for Children: the risk of inappropriate paracetamol prescribing. Arch Dis Child 2012; 97: 279-82.

10. Fingleton J, Weatherall M, Beasley R. Bronchodilator responsiveness: interpret with caution. Thorax 2012; 67: 667-8.

11. Hall G, Thompson BR, Stanojevic S, Abramson MJ, Beasley R, Coates A, Dent A, Eckert B, James A, Filsell S, Musk AW, Nolan G, Dixon B, O’Dea C, Savage J, Stocks J, Swanney MP. The global lung initiative 2012 reference values reflect contemporary Australasian spirometry. Respirology 2012; 17: 1150-1.

12. Harwood M, Weatherall M, Talemaitoga A, Barber PA, Gommans J, Taylor W, McPherson K, McNaughton H. Taking charge after stroke: promoting self-directed rehabilitation to improve quality of life: a randomized controlled trial. Clin Rehabil 2012;26: 493-501.

13. Jefferies S, Weatherall M, Young P, Eyers S, Beasley R. Systematic review and meta-analysis of the effects of antipyretic medications on mortality in Streptococcus pneumoniae infections. Postgrad Med J 2012; 88: 21-7.

14. Mitchell EA, Beasley R, Keil U, Montefort S, Odhiambo J and the ISAAC

Phase Three Study Group. The association between tobacco and the risk of asthma, rhinoconjunctivitis and eczema in children and adolescents: analyses from Phase Three of the ISAAC programme. Thorax 2012; 67: 941-9.

15. Patel M, Pilcher J, Chan A, Perrin K, Black P, Beasley R. Six-month in vitro validation of a metered-dose inhaler electronic monitoring device: Implications for asthma clinical trial use. J Allergy Clin Immunol 2012; Doi: 10.1016/j. jaci.2012.06.037.

16. Pilcher JM, Weatherall M, Shirtcliffe P, Bellomo R, Young P, Beasley R. The effect of hyperoxia following cardiac arrest — a systematic review and meta-analysis of animal trials. Resuscitation 2012; 83: 417-22.

17. Ranchord AM, Argyle R, Beynon R, Perrin K, Sharma V, Weatherall M, Simmonds M, Heatlie G, Brooks N, Beasley R on behalf of the OPTIMISE Study Group. High concentration vs titrated oxygen therapy in ST elevation myocardial infarction: a pilot randomized controlled trial. Am Heart J 2012; 163: 168-75.

18. Ranchord AM, Perrin K, Weatherall M, Beasley R, Simmonds M. A randomised controlled trial of the effect of high concentration oxygen on myocardial ischaemia during exercise. Int J Cardiol 2012; 160: 201-5.

19. Raymond NJ, Berry N, Blackmore TK, Jefferies S, Norton K, Perrin K, Beasley R. Pandemic influenza A(H1N1) 2009 in hospital healthcare workers in New Zealand. Infect Control Hosp Epidemiol 2012; 33: 196-9.

20. Salvi S, Manap R, Beasley R. Understanding the true burden of COPD: the epidemiological challenges. Prim Care Resp J 2012; 21: 249-51.

21. Shirtcliffe P, Marsh S, Travers J, Weatherall M, Beasley R. Childhood asthma and GOLD-defined chronic obstructive pulmonary disease. Int Med J 2012; 42: 83-8.

22. Travers J, Weatherall M, Fingleton J, Beasley R. Towards individualised medicine for airways disease: identifying clinical phenotype groups. Eur Respir J 2012; 39: 1033-4 (letter).

23. Wijesinghe M, Perrin K, Healy B, Weatherall M, Beasley R. Randomized controlled trial of high concentration in suspected community-acquired pneumonia. J Roy Soc Med 2012; 105: 208-16.

24. Williams JM, Young P, Pilcher J, Weatherall M, Miller JH, Beasley R, La Flamme AC. Remote ischemic preconditioning does not alter perioperative cytokine production in highrisk cardiac surgery. Heart Asia 2012; 4: 97-101.

25. Young P, Beasley R, Bailey M, Bellomo R, Eastwood GM, Nichol A, Pilcher D, Yunos NM, Egi M, Hart GK, Reade MC, Cooper DJ for the Study of Oxygen in Critical Care (SOCC) Group. The association between early arterial oxygenation and mortality in ventilated patients with acute ischaemic stroke. Crit Care Resusc 2012; 14: 14-9.

26. Young PJ, Dalley P, Garden A, Horrocks C, La Flamme A, Mahon B, Miller J, Pilcher J, Weatherall M, Williams J, Young W, Beasley R. A pilot study investigating the effects of remote ischemic preconditioning in high-risk cardiac surgery using a randomised controlled doubleblind protocol. Basic Res Cardiol 2012; 107: 25665.

27. Young PJ, Saxena M, Beasley R, Bellomo R, Bailey M, Pilcher D, Finfer S, Harrison D, Myburgh J, Rowan K. Early peak temperature and mortality in critically ill patients with or without infection. Int Care Med 2012; 38: 437-44.

2011

1. Aldington S, Shirtcliffe P, Nowitz M, Kingzett-Taylor, Tweed M, Weatherall M, Soriano J, Beasley R. Incidental findings from lung CT scans: implications for research. J Med Imaging Radiation Oncol 2011; 55; 20-5.

2. Beasley R, Patel M, Perrin K, O’Driscoll BR. High concentration oxygen therapy in COPD. Lancet 2011; 378: 969-70.

3. Beasley RW, Clayton TO, Crane J, Lai CKW, Montefort SR, von Mutius E, Stewart AW and the ISAAC Phase Three Study Group. Acetaminophen use and risk of asthma, rhinoconjunctivitis and eczema in adolescents: ISAAC Phase Three. Am J Respir Crit Care Med 2011; 183: 171-8.

4. Charles T, Mackintosh D, Healy B, Perrin K, Weatherall M, Beasley R. Merino wool graduated compression stocking increases lower limb venous blood flow: a randomized controlled trial. Adv Ther 2011; 28: 227-37.

5. Edwards L, Jefferies S, Healy B, Weatherall M, Beasley R, Shirtcliffe P. What risk do consumers face when seeking medical advice from health food stores? NZMJ 2011; 124(1334): 81-8.

6. Edwards L, Perrin K, Wijesinghe M, Weatherall M, Beasley R, Travers J. The value of the CRB65 score to predict mortality in exacerbations of COPD requiring hospital admission. Respirol 2011; 16; 625-9.

7. Eyers S, Jefferies S, Shirtcliffe P, Perrin K, Beasley R. Antipyretic therapy for influenza infection — benefit or harm? NZ Med J 2011; 124: 126-8.

8. Eyers S, Weatherall M, Jefferies S, Beasley R. Paracetamol in pregnancy and the risk of wheezing in offspring: a systematic review and meta-analysis. Clin Exper Allergy 2011; 41: 482-9.

9. Fingleton J, Weatherall M, Beasley R. Towards individualised treatment in COPD. Thorax 2011; 66: 363-4.

10. Iscoe S, Beasley R, Fisher JA. Supplementary oxygen for non-hypoxemic patients: O2 much of a good thing? Crit Care 2011; 15: 305-7.

11. Jefferies S, Earl D, Berry N, Blackmore T, Rooker S, Raymond N, Pritchard A, Weatherall M, Beasley R, Perrin K. Effectiveness of the 2009 seasonal influenza vaccine against pandemic influenza A(H1N1)2009 in healthcare workers in New Zealand, June-August 2009. Euro Surveill 2011 Jan 13;16(2).

12. Jefferies S, Weatherall M, Young P, Beasley R. A systematic review of the accuracy of peripheral thermometry in estimating core temperatures among febrile critically ill patients. Crit Care Resus 2011; 13: 194-9.

13. Jefferies S, Weatherall M, Young P, Eyers S, Perrin KG, Beasley CRW. The effect of antipyretic medications on mortality in critically ill patients with infection: a systematic review and meta-analysis. Crit Care Resusc 2011; 13: 125-31.

14. Knott C, Psirides A, Young PJ, Sim D. A retrospective cohort study of the effect of medical emergency teams on documentation of advance care directives. Crit Care Resus. 2011; 13(3): 167-74.

15. MacDonald M, Beasley RW, Irving L, Bardin PG. A hypothesis to phenotype COPD exacerbations by aetiology. Respirol 2011; 16: 264-8.

16. Maher L, Young PJ. Cardiac arrest complicating neostigmine use for bowel opening in a critically ill patient. Crit Care Resus. 2011; 13(3): 192-93.

17. Patel M, Perrin K, Beasley R. Beta agonist use during asthma exacerbations: how much is too much? NZMJ 2011; 124(1332): 77-80.

18. Perrin K, Wijesinghe M, Healy B, Wadsworth K, Bowditch R, Bibby S, Baker T, Weatherall M, Beasley R. Randomised controlled trial of high concentration versus titrated oxygen therapy in severe exacerbations of asthma. Thorax 2011; 66: 937-41.

19. Perrin K, Wijesinghe M, Weatherall M, Beasley R. Assessing PaCO2 in acute respiratory disease: accuracy of a transcutaneous carbon dioxide device. Int Med J 2011; 41: 630-3.

20. Robinson GM, Judson G, Loan R., Bevin T, O’Connor P. Patterns of prescription drug misuse presenting to provincial drug clinics. NZ Medical J 2011;124.

21. Saxena M, Hammond N, Taylor C, Young PJ, Reade M, Bellomo R, Myburgh J. A survey of fever management in febrile intensive care patients without neurological injury. Criti Care Resusc 2011; 13: 238-43.

22. Shirtcliffe P, Weatherall M, Travers J, Beasley R. The multiple dimensions of airways disease: targeting treatment to clinical phenotypes. Curr Opin Pulm Med 2011; 17: 72-8.

23. Thompson BR, Stanojevic S, Abramson MJ, Beasley R, Coates A, Dent A, Eckert B, James A, Filsell S, Musk AW, Nolan G, Dixon B, O’Dea C, Savage J, Stocks J, Swanney MP, Hall GL on behalf of the ANZSRS Reference Ranges Working Party. The all-age spirometry reference ranges reflect contemporary Australasian spirometry. Respirol 2011; 16: 912-7.

24. Wickens K, Beasley R, Town I, Epton M, Pattemore P, Ingham T, Crane J. New Zealand Asthma and Allergy Cohort Study Group. The effects of early and late paracetamol exposure on asthma and atopy: a birth cohort. Clin Exper Allergy 2011; 41: 399-406.

25. Wijesinghe M, Perrin K, Healy B, Hart K, Clay J, Weatherall M, Beasley R. Pre-hospital oxygen therapy in acute exacerbations of chronic obstructive pulmonary disease. Int Med J 2011; 41: 618-22.

26. Wijesinghe M, Williams M, Perrin K, Weatherall M, Beasley R. The effect of supplemental oxygen on hypercapnia in patients with obesity-associated hypoventilation: a randomized cross-over clinical study. Chest 2011; 139: 1018-24.

27. Young P, Saxena M, Eastwood GM, Bellomo R, Beasley R. Fever and fever management among intensive care patients with known or suspected infection: a multicentre prospective cohort study. Crit Care Resusc 2011; 13: 97-102.

28. Young PJ, Saxena MK, Beasley RW. Fever and antipyresis in infection. MJA 2011; 195: 458-9.

2010

1. Anderson HR, Ruggles R, Pandey KD, Kapetanakis V, Brunekreef B, Lai CKW, Strachan DP, Weiland SK, ISAAC Phase One Study Group. Ambient particulate pollution and the worldwide prevalence of asthma, rhinoconjunctivitis and eczema in children: Phase One of the International Study of Asthma and Allergies in Childhood (ISAAC). Occup Environ Med; 2010; 67:293-300.

2. Asher MI, Stewart AW, Mallol J, Montefort S, Lai CKW, Aït-Khaled N, Odhiambo J, The ISAAC Phase One Study Group. Which population level environmental factors are associated with asthma, rhinoconjunctivitis and eczema? Review of the ecological analyses of ISAAC Phase One. Respir Res 2010; 11: 8.

3. Bandaranayake D, Huang S, Bissielo A, Wood T, Mackereth G, Baker MG, Beasley R, Reid S, Roberts S, Hope V on behalf of the 2009 H1N1 serosurvey investigation team. Risk factors and immunity in a nationally representative population following the 2009 influenza A(H1N1) pandemic. PLoS One 2010; 5: e13211.

4. Beasley R, Perrin K, Weatherall M, Wijesinghe M. Call for withdrawal of LABA single inhaler therapy in asthma. Lancet 2010; 376: 750-1.

5. Beasley R, Perrin K, Wijesinghe M. Routine oxygen therapy in myocardial infarction —primum non nocere. BMJ 2010; (9 July).

6. Bibby S, Healy B, Steele R, Kumareswaran K, Nelson H, Beasley R. Association between leukotriene receptor antagonist therapy and Churg-Strauss syndrome: an analysis of the FDA AERS database. Thorax 2010; 65: 132-8.

7. Büchele G, Genuneit J, Weinmayr G, Björkstén B, Gehring U, von Mutius E, Priftanji A, Stein RT, Addo-Yobo EO, Priftis KN, Shah JR, Forastiere F, Svabe V, Crane J, Nystad W, GarciaMarcos L, Saraçlar Y, El-Sharif N, Strachan DP, ISAAC Phase Two Study Group. International variations in bronchial responsiveness in children: findings from ISAAC Phase Two. Pediatr Pulmonol 2010; 45: 796-806.

8. Ellwood P, Asher MI, Stewart AW and the ISAAC Phase III Study Group. The impact of consent on response rates in the ISAAC time trends study. Int J Tuberc Lung Dis 2010; 14: 1059-65.

9. Eyers S, Weatherall M, Shirtcliffe P, Perrin K, Beasley R. The effect on mortality of antipyretics in the treatment of influenza infection: systematic review and meta-analysis. J R Soc Med 2010; 103: 403-11.

10. Farquhar H, Stewart A, Mitchell E, Crane J, Eyers S, Weatherall M, Beasley R. The role of paracetamol in the pathogenesis of asthma. Clin Exper Allergy 2010; 40: 32-41.

11. Hancox RJ, Beasley R. Programming in asthma: the dice are loaded but not cast [Editorial]. Clin Exper Allergy 2010; 40: 1717-8.

12. Hancox RJ, Le Souëf PN, Anderson GP, Reddel HK, Chang AB, Beasley R. Asthma: Time to confront some inconvenient truths. Respirol 2010; 15: 194-201.

13. Healy B, Beasley R, Weatherall M. Venous thromboembolism following prolonged cast immobilisation for injury to the tendo Achillis. J Bone Joint Surg — British Volume 2010; 92: 646-50.

14. Healy B, Levin E, Perrin K, Weatherall M, Beasley R. Prolonged work — and computerrelated seated immobility and risk of venous thromboembolism. J R Soc Med 2010; 103: 44754.

15. Holt S. Asthma control test scores obtained from an asthma NZ educational activity. NZMJ 2010; 123: 109-10.

16. Holt S, Holt A, Erasmus P, Watson M, Farrell T, Blackshaw G, Poppe M, Williams M, Gilbey A. A survey of use and knowledge of vitamins and supplements in the Bay of Plenty, New Zealand. NZMJ 2010; 123: 114-6.

17. Iscoe S, Beasley R, Fisher JA. Arterial hyperoxia and in-hospital mortality after resuscitation from cardiac arrest. JAMA 2010; 304: 1440-1.

18. Murray CS, Custovic A, Lowe LA, Aldington S, Williams M, Beasley R, Woodcock A. Effect of addition of salmeterol versus doubling the dose of fluticasone propionate on specific airway resistance in children with asthma. Allergy & Asthma Proceedings 2010; 31: 415-21.

19. Nagel G, Weinmayr G, Kleiner A, GarciaMarcos L, Strachan DP. Effect of diet on asthma and allergic sensitisation in the International Study on Allergies and Asthma in Childhood (ISAAC) Phase Two. Thorax 2010; 65: 516-22

20. O’Driscoll BR, Beasley R. Avoidance of high concentration oxygen in chronic obstructive pulmonary disease. BMJ 2010; 341: c5549.

21. Perrin K, Williams M, Wijesinghe M, James K, Weatherall M, Beasley R. Randomized controlled trial of adherence with single or combination inhaled corticosteroid/long-acting ß-agonist inhaler therapy in asthma. J Allergy Clin Immunol 2010; 126: 505-10.

22. Robinson GM, Robinson S, McCarthy P, Cameron C. Misuse of over-the-counter codeinecontaining analgesics: dependence and other adverse effects. NZMJ 2010; 123(1317).

23. Thompson I, Williams G, Caldwell B, Aldington S, Dickson S, Lucas N, McDowall J, Weatherall M, Robinson G, Beasley R. Randomised double-blind, placebo-controlled trial of the effects of the “party pills” BZP/ TFMPP alone and in combination with alcohol. J Psychopharmacol 2010; 24: 1299-308.

24. Weatherall M, Shirtcliffe P, Travers J, Beasley R. Use of cluster analysis to define COPD phenotypes [Editorial]. Eur Respir J 2010; 36: 472-4.

25. Weatherall M, Wijesinghe M, Perrin K, Beasley R. Long-acting beta-agonists and asthma death: how useful are different study designs to evaluate the potential association? J Asthma 2010; 47: 434-8.

26. Weatherall M, Wijesinghe M, Perrin K, Harwood M, Beasley R. Meta-analysis of the risk of mortality with salmeterol and the effect of concomitant inhaled corticosteroid therapy. Thorax 2010; 65: 39-43.

27. Weinmayr G, Genuneit J, Nagel G, Bjorksten B, van Hage M, Priftanji A, Cooper P, Rijkjarv MA, von Mutius E, Tsanakas J, Forastiere F, Doekes G, Garrido JB, Suarez-Varela MM, Braback L, Strachan DP. ISAAC Phase Two Study Group. International variations in associations of allergic markers and diseases in children: ISAAC Phase Two. Allergy 2010; 65:766-75.

28. Wijesinghe M, Shirtcliffe P, Perrin K, Healy B, James K, Weatherall M, Beasley R. An audit of the effect of oxygen prescription charts on clinical practice. Postgrad Med J 2010; 86: 89-93.

2009

1. Aït-Khaled N, Pearce N, Anderson HR, Ellwood P, Montefort S, Shah J and the ISAAC Phase Three Study Group. Global map of the prevalence of symptoms of rhinoconjunctivitis in children: The International Study of Asthma and Allergy in Childhood (ISAAC) Phase Three. Allergy 2009; 64: 123-48.

2. Beasley R, Clayton T, Crane J, von Mutius E, Lai CKW. Paracetamol as a risk factor for allergic disorders. Lancet 2009; 373: 120-1 (letter).

3. Beasley R, Martinez F, Hackshaw A, Rabe KF, Sterk PJ, Djukanovic R. Safety of longacting beta agonists: urgent need to clear the air remains. Eur Respir J 2009; 33: 3-5.

4. Beasley R, Weatherall M, Travers J, Shirtcliffe P. Time to define the disorders that make up the syndrome of COPD. Lancet 2009; 374: 670-2.

5. Beasley R, Wijesinghe M, Weatherall M. Potential risks of using LABAs with ICS therapy. Am J Respir Crit Care Med 2009; 180: 581 (letter).

6. Brunekreef B, Stewart AW, Anderson HR, Lai CKW, Pearce NE and the Phase Three Study Group. Self-reported truck traffic on the street of residence and symptoms of asthma and allergic disease: a global relationship in ISAAC Phase Three. Environ Health Perspect 2009; 117: 1791-8.

7. Ellwood P, Williams H, Aït-Khaled N, Björkstén B, Robertson C and the ISAAC Phase III Study Group. Translation of questions: the International Study of Asthma and Allergies in Childhood (ISAAC) experience. Int J Tuberc Lung Dis 2009; 13: 1174-82.

8. Farquhar H, Crane J, Mitchell EA, Eyers S, Beasley R. The acetaminophen and asthma hypothesis 10 years on: a case to answer. J Allergy Clin Immunol 2009; 124: 649-51.

9. Farquhar H, Weatherall M, Wijesinghe M, Perrin K, Ranchord A, Simmonds M, Beasley R. Systematic review of studies of the effect of hyperoxia on coronary blood flow. Am Heart J 2009; 158: 371-7.

10. Flohr C, Weinmayr G, Weiland SK, AddoYobo E, Annesi-Maesano I, Björkstén B, Bråbäck L, Büchele G, Chico M, Cooper P, Clausen M, El Sharif N, Martinez Gimeno A, Mathur RS, von Mutius E, Morales Suarez-Varela M, Pearce N, Svabe V, Wong GWK, Yu M, Zhong NS, Williams HC and the ISAAC Phase Two Study Group. How well do questionnaires perform compared with physical examination in detecting flexural eczema? Findings from the International Study of Asthma and Allergies in Childhood (ISAAC) Phase Two. Br J Dermatol 2009; 161: 846-53.

11. Foliaki S, Pearce N, Björkstén B, Mallol J, Montefort S, von Mutius E and the International Study of Asthma and Allergies in Childhood Phase III Study Group. Antibiotic use in infancy and symptoms of asthma, rhinoconjunctivitis, and eczema in children 6 and 7 years old: International Study of Asthma and Allergies in Childhood Phase III. J Allergy Clin Immunol 2009; 124: 982-9.

12. Genuneit J, Cantelmo JL, Weinmayr G, Wong GWK, Cooper PJ, Riikjärv M-A, Gotua M, Kabesch M, von Mutius E, Forastiere F, Crane J, Nystad W, El-Sharif N, Batlles-Garrido J, GarciaMarcos L, Garcia-Hernández G, Morales-SuarezVarela M, Nilsson L, Bråbäck L, Saraçlar Y, Weiland SK, Cookson WOC, Strachan D, Moffatt MF and the ISAAC Phase 2 Study Group. A multicentre study of candidate genes for wheeze and allergy: the International Study of Asthma and Allergies in Childhood Phase 2. Clin Exper Allergy 2009; 39: 1875-88.

13. Hart K, Weatherall M, Shirtcliffe P, Beasley R. Frequency of dosing and comparative doses of mometasone furoate: a meta-analysis. Respirol 2009; 14: 1166-72.

14. Holt S, Gilbey A. A survey of New Zealand patients’ preferred characteristics of their general practitioners. NZMJ 2009; 122(1307): 127-8.

5. Holt S, Gilbey A. Beliefs about homeopathy among patients presenting at GP surgeries. NZMJ 2009; 122: 94-95.

16. Holt S, Gilbey A. Response to letter from the NZ council of homeopaths. NZMJ 2009; 122: 87-88.

17. Holt S, Gilbey A. Use of placebos by New Zealand doctors. NZMJ 2009; 122: 84-86.

18. Holt S, Helm C, Corin A, Tofield C, Williams M, Weatherall M. A pilot study of the efficacy of a vitamin C-containing showerhead on symptoms of eczema. NZMJ 2009; 122: 91-92.

19. Holt S. New Zealand general practitioners’ opinions of the polypill concept. NZMJ 2009; 122: 116-117.

20. Holt S. Time to implement the polypill approach. NZMJ 2009;1 22: 88-89.

21. Judson G, Bird R, O’Connor P, Bevin T, Loan R, Schroder M, McGrath R, Weatherall M, Moriarty H, Robinson G. Drug injecting in patients in New Zealand methadone maintenance treatment programs: an anonymous survey. Drug Alcohol Rev 2010; 29: 41-6.

22. Lai CKW, Beasley R, Crane J, Foliaki S, Shah J, Weiland S, the ISAAC Phase Three Study Group. Global variation in the prevalence and severity of asthma symptoms: Phase Three of the International Study of Asthma and Allergies in Childhood (ISAAC). Thorax 2009; 64: 476-83.

23. Levin E, Macintosh D, Baker T, Weatherall M, Beasley R. Effect of sitting in ergonomic chairs on lower limb venous blood flow. Occupational Ergonomics 2008/2009; 8: 125-32.

24. McPherson K, Kayes N, Weatherall M on behalf of all members of the Goal-SR Research Group. A pilot study of self-regulation informed goal setting in people with traumatic brain injury. Clin Rehab 2009; 23: 296-309.

25. Nagel G, Büchele G, Weinmayr G, Björkstén B, Chen Y-Z, Wang H, Nystad W, Saraclar Y, Bråbäck L, Batlles-Garrido J, GarciaHernandez G, Weilland SK and the ISAAC Phase II Study Group. Effect of breastfeeding on asthma, lung function and bronchial hyperreactivity in ISAAC Phase II. Eur Respir J 2009: 33: 993-1002.

26. Odhiambo J, Williams H, Clayton T, Robertson C, Asher MI and the ISAAC Phase Three Study Group. Global variations in prevalence of eczema symptoms in children from ISAAC Phase Three. J Allergy Clin Immunol 2009; 124: 1251-8.

27. Sellman JD, Robinson GM, Beasley R. Should ethanol be scheduled as a drug of high risk to public health? J Psychopharmacol 2009; 23: 94-100.

28. Siebers R, Holt S, Healy B, Beasley R, Burgess C. High blood pressure advice given by natural health food stores. NZMJ 2009; 122(1293): 11-15.

29. Weatherall M, Clay J, James K, Perrin K, Shirtcliffe P, Beasley R. Dose-response relationship of inhaled corticosteroids and cataracts: a systematic review and metaanalysis. Respirology 2009; 14: 983-90.

30. Weatherall M, Marsh S, Shirtcliffe P, Williams M, Travers J, Beasley R. Quality of life measured by the St George’s Respiratory Questionnaire and spirometry. Eur Respir J 2009; 33: 1025-30.

31. Weatherall M, Travers J, Shirtcliffe PM, Marsh SE, Williams MV, Nowitz MR, Aldington S, Beasley R. Distinct clinical phenotypes of airways disease defined by cluster analysis. Eur Respir J 2009; 34: 812-8.

32. Wijesinghe M, Perrin K, Ranchord A, Simmonds M, Weatherall M, Beasley R. Routine use of oxygen in the treatment of myocardial infarction: systematic review. Heart 2009; 95: 198-202.

33. Wijesinghe M, Weatherall M, Perrin K, Beasley R. Honey in the treatment of burns: a systematic review and meta-analysis of its efficacy. NZMJ 2009; 122: 19-23.

34. Wijesinghe M, Weatherall M, Perrin K, Crane J, Beasley R. International trends in asthma mortality rates in the 5-to 34-year age group: a call for closer surveillance. Chest 2009; 135: 1045-9.

35. Wijesinghe M, Weatherall M, Perrin K, Harwood M, Beasley R. Risk of mortality associated with formoterol: a systematic review and meta-analysis. Eur Respir J 2009; 34: 80311.

2008

1. Aldington S, Harwood M, Cox B, Weatherall M, Beckert L, Hansell A, Pritchard A, Robinson G, Beasley R. Cannabis use and risk of lung cancer: a case-control study. Eur Respir J 2008; 31: 280-6.

2. Aldington S, Harwood M, Cox B, Weatherall M, Beckert L, Hansell A, Pritchard A, Robinson G, Beasley R. Cannabis use and cancer of the head and neck: case-control study. Otolaryngol — Head & Neck Cancer 2008; 138: 374-80.

3. Aldington S, Pritchard A, Perrin K, James K, Wijesinghe M, Beasley R. Prolonged seated immobility at work is a common risk factor for venous thromboembolism leading to hospital admission. Int Med J 2008; 38: 133-5.

4. Anderson HR, Gupta R, Kapetanakis V, Asher MI, Clayton T, Robertson CF, Strachan DP and the ISAAC Steering Committee. International correlations between indicators of prevalence, hospital admissions and mortality for asthma in children. Int J Epidemiol 2008; 37: 573-82.

5. Beasley R, Bibby S, Weatherall M. Leukotriene receptor antagonist therapy and Churg-Strauss Syndrome — culprit or innocent bystander? Thorax 2008; 63: 847-9.

6. Beasley R, Clayton T, Crane J, von Mutius E, Lai CKW, Montefort S, Stewart A and the ISAAC Phase Three Study Group. Association between paracetamol use in infancy and childhood, and risk of asthma, rhinoconjunctivitis, and eczema in children aged 6-7 years: analysis from Phase Three of the ISAAC programme. Lancet 2008; 372: 1039-48.

7. Björkstén B, Clayton T, Ellwood P, Stewart A, Strachan D and the ISAAC Phase Three Study Group. Global time trends for symptoms of rhinoconjunctivitis: Phase Three of the International Study of Asthma and Allergies in Childhood (ISAAC). Pediatr Allergy Immunol 2008; 19: 110-24.

8. Flohr C, Weiland SK, Weinmayr G, Björkstén B, Bråbäck L, Brunekreef B, Büchele G, Clausen M, Cookson WOC, von Mutius E, Strachan DP, Williams HC and the ISAAC Phase Two Study Group. The role of atopic sensitization in flexural eczema: findings from the International Study of Asthma and Allergies in Childhood Phase Two. J Allergy Clin Immunol 2008; 121: 141-7.

9. Gehring U, Strikwold M, Schram-Bijkerk D, Weinmayr G, Genuneit J, Nagel G, Wickens K, Siebers R, Crane J, Doekes G, Di Domenicantonio R, Nilsson L, Priftanji A, Sandin A, El-Sharif N, Strachan D, van Hage M, von Mutius E, Brunekreef B, ISAAC Phase Two Study Group. Asthma and allergic symptoms in relation to house dust endotoxin: Phase Two of the International Study on Asthma and Allergies in Childhood (ISAAC II). Clin Exper Allergy 2008; 38: 1911-20.

10. Holt S. The responses of alternative practitioners when approached about common childhood illnesses. NZMJ 2008; 114-6.

11. Holt S, Walker P. Much room for improvement — Asthma Survey reveals high levels of inadequately controlled asthma. New Zealand Pharmacy August 2008; 24-5.

12. Loh LC, Hui DS, Beasley R. Introduction: Avian influenza: from basic biology to pandemic planning. Respirology 2008; 13 Suppl 1: S1.

13. Ly Q, Ashgar M, Young J, Robinson G, Weatherall M. Medication histories — can pharmacist training of junior medical staff improve accuracy? NZ Pharmacy J 2008; 11: 203.

14. Marsh SE, Travers J, Weatherall M, Williams MV, Aldington S, Shirtcliffe PM, Hansell AL, Nowitz MR, McNaughton AA, Soriano JB, Beasley RW. Proportional classifications of COPD phenotypes. Thorax 2008; 761-7.

15. Ministry of Health. Diabetes and Cardiovascular Disease Quality Improvement Programme. Wellington, Ministry of Health 2008.

16. Robinson G. Doctors’ poor health – still an issue? Medical Council News 2008; 46: 7-8.

17. Robinson G, McCann K, Freeman P, Beasley R. The New Zealand national junior doctors’ strike: implications for the provision of acute hospital medical services. Clin Med 2008; 8: 272-5.

18. Weatherall M, James K, Clay J, Perrin K, Masoli M, Wijesinghe M, Beasley R. Doseresponse relationship for risk of non-vertebral fracture with inhaled corticosteroids. Clin Exp Allergy 2008; 38: 1451-8.

19. Weinmayr G, Forastiere F, Weiland SK, Rzehak P, Abramidze T, Annesi-Maesano I, Björkstén B, Brunekreef B, Büchele G, Cookson WOC, von Mutius E, Pistelli R, Strachan DP and the ISAAC Phase Two Study Group. International variation in prevalence of rhinitis and its relationship with sensitisation to perennial and seasonal allergens. Eur Respir J 2008; 32: 125061.

20. West J, Perrin K, Aldington S, Weatherall M, Beasley R. A case-control study of seated immobility at work as a risk factor for venous thromboembolism. J R Soc Med 2008; 101: 237-43.

21. Wijesinghe M, Perrin K, Harwood M, Weatherall M, Beasley R. The risk of asthma mortality with inhaled long acting ß-agonists. Postgrad Med J 2008; 84: 467-72.

22. Williams H, Stewart A, von Mutius E, Cookson B, Anderson HR and the International Study of Asthma and Allergies in Childhood (ISAAC) Phase One and Three Study Groups. Is eczema really on the increase worldwide? J Allergy Clin Immunol 2008; 121: 947-54.

2007

1. Aldington S, Beasley R. The assessment and management of severe asthma in adults in hospital. Thorax 2007; 62: 447-58.

2. Aldington S, Thompson I, Robinson G, Beasley R. From medical student to junior doctor: information technology in medicine – a prerequisite for clinical competency. StudentBMJ 2007; 14: 194-6.

3. Aldington S, Williams M, Nowitz M, Weatherall M, Pritchard A, McNaughton A, Robinson G, Beasley R. Effects of cannabis on pulmonary structure, function and symptoms. Thorax 2007; 62: 1058-63.

4. Beasley R, Aldington S, Robinson G. Is it time to change the approach to oxygen therapy in the breathless patient? Thorax 2007; 62: 840-1.

5. Beasley R, Aldington S, Weatherall M, Robinson G, McHaffie D. Oxygen therapy in myocardial infarction: an historical perspective. J R Soc Med 2007; 100: 130-3.

6. Beasley R, Aldington S. Magnesium in the treatment of asthma. Curr Opin Allergy Clin Immunol 2007; 7: 107-10.

7. Braye K, Harwood TJS, Inder R, Beasley R, Robinson GM. Poppy seed tea: an increasing opiate abuse phenomenon in New Zealand. Drug & Alcohol Review 2007; 26: 215-9.

8. Caldwell B, Beasley R, Weatherall M, Metcalfe S. Balancing the risks and benefits of celecoxib. Am J Med 2007; 120: e17.

9. Charles T, Quinn D, Weatherall M, Aldington S, Beasley R, Holt S. An audiovisual reminder function improves adherence with inhaled corticosteroid therapy in asthma. J Allergy Clin Immunol 2007; 119: 811-6.

10. Lee YC, Beasley R. Respirology year-inreview 2006: clinical science. Respirology 2007; 12: 6-15.

11. Marsh S, Aldington S, Williams M, Weatherall M, Robiony-Rogers D, Jones D, Beasley R. Plumonary function testing in New Zealand: the use and importance of reference ranges. Respirology 2007; 12: 367-74.

12. Marsh S, Aldington S, Williams MV, Nowitz MR, Kingzett-Taylor A, Weatherall M, Shirtcliffe PM, McNaughton AA, Pritchard A, Beasley R. Utility of lung density measurements in the diagnosis of emphysema. Respir Med 2007; 101: 1512-20.

13. Pearce N, Aït-Khaled N, Beasley R, Mallol J, Keil U, Mitchell E, Robertson C and the ISAAC Phase Three Study Group. Worldwide trends in the prevalence of asthma symptoms: Phase Three of the International Study of Asthma and Allergies in Childhood (ISAAC). Thorax 2007; 62: 758-66.

14. Robinson G, Morreau J, Leighton M, Beasley R. New hospital consultant: surviving a difficult period. NZ Med J 2007; 120(1259): U2662.

15. Robinson G, Narasimhan S, Weatherall M, Beasley R. Hemochromatosis gene mutations, liver function tests and iron status in alcohol-dependent patients admitted for detoxification. J Gastroenterol Hepatol 2007; 22: 852-61.

16. Shirtcliffe P, Weatherall M, Marsh S, Travers J, Hansell A, McNaughton A, Aldington S, Muellerova H, Beasley R. COPD prevalence in a random population survey: a matter of definition. Eur Respir J 2007; 30: 232-9.

17. Travers J, Marsh S, Aldington S, Williams M, Shirtcliffe P, Pritchard A, Weatherall M, Beasley R. Reference ranges for exhaled nitric oxide derived from a random community survey of adults. Am J Respir Crit Care Med 2007; 176: 238-42.

18. Travers J, Marsh S, Caldwell B, Williams M, Aldington S, Weatherall M, Shirtcliffe P, Beasley R. External validity of randomized controlled trials in COPD. Respir Med 2007; 101: 1313-20.

19. Travers J, Marsh S, Williams M, Weatherall M, Caldwell B, Shirtcliffe P, Aldington S, Beasley R. External validity of randomised controlled trials in asthma: to whom do the results of the trials apply? Thorax 2007; 62: 21923.

20. Weinmayr G, Weiland SK, Björkstén B, Brunekreef B, Büchele G, Cookson WOC, Garcia-Marcos L, Gotua M, Gratziou C, van Hage M, von Mutius E, Riikjärv M-A, Rzehak P, Stein RT, Strachan DP, Tsanakas J, Wickens K, Wong GW, ISAAC Phase Two Study Group. Atopic sensitization and the international variation of asthma symptom prevalence in children. Am J Respir Crit Care Med 2007; 176: 565-74.

2006

1. Aldington S, Beasley R, Robinson G. From medical student to junior doctor: working outside the box. StudentBMJ (June) 2006; 14: 238-9.

2. Aldington S, Robinson G, Beasley R. Improving the use and interpretation of diagnostic tests in pulmonary embolism. NZMJ 2006; 119(1237): U2057.

3. Aldington S, Robinson GM, Beasley R. From medical student to junior doctor: care of the deceased patient. StudentBMJ (February) 2006;1 4: 60-1.

4. Aldington S, Williams M, Weatherall M, Beasley R. Duration of action of the salmeterol/ fluticasone combination inhaler administered in the evening: a randomized controlled trial in childhood asthma. Respirology 2006; 11: 638-42.

5. Asher MI, Montefort S, Björkstén B, Lai CKW, Strachan DP, Weiland SK, Williams H, ISAAC Phase Three Study Group. Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys. Lancet 2006; 368: 733-43.

6. Balm MN, Truong HT, Choudhary AS, Robinson GM, Blackmore TK. Streptococcus gallinaceus bacteraemia in an abattoir worker presenting with a febrile illness. J Med Microbiol 2006; 55(Pt 7): 957-9.

7. Barnes ML, Lipworth BJ, Weatherall M, Masoli M, Beasley R. Clinical importance of the Step 3 choice in asthma. Thorax 2006; 61(2):1801.

8. Beasley R. A historical perspective of the New Zealand asthma mortality epidemics. J Allergy Clin Immunol 2006; 117: 225-8.

9. Beasley R, McNaughton A, Robinson G. New look at the oxyhaemoglobin dissociation curve. Lancet 2006; 367: 1124-6.

10. Beasley R, Robinson G, Aldington S. From medical student to junior doctor: accepting the responsibility of informed consent. StudentBMJ (March) 2006; 14: 94-6.

11. Bernau S, Aldington S, Robinson G, Beasley R. From medical student to junior doctor: the medical handover — a good habit to cultivate. StudentBMJ (May) 2006; 14: 188-9.

12. Burgess C, Blaikie A, Ingham T, Robinson G, Narasimhan S. Monitoring the use of amiodarone: compliance with guidelines. Int Med J 2006; 36: 289-93.

13. Caldwell B, Aldington S, Weatherall M, Shirtcliffe P, Beasley R. Risk of cardiovascular events and celecoxib: a systematic review and meta-analysis. J R Soc Med 2006; 99: 132-40.

14. Chapman KR, Mannino DM, Soriano JB, Vermeire PA, Buist AS, Thun MJ, Connell C, Jemal A, Lee TA, Miravitiles M, Aldington S, Beasley R. Epidemiology and costs of chronic obstructive pulmonary disease. Eur Respir J 2006; 27: 188-207.

15. Feigin V, Carter K, Hackett M, Barber PA, McNaughton H, Dyall L, Chen MH, Anderson C. Auckland Regional Community Stroke Study Group. Ethnic disparities in incidence of stroke subtypes: Auckland Regional Community Stroke Study, 2002-2003. Lancet Neurology 2006; 5: 130-9.

16. Hughes R, Heuser T, Hill S, RyderLewis S, Weatherall M, Hopkins R, Beasley R. Recent air travel and venous thromboembolism resulting in hospital admission. Respirology 2006; 11: 75-9.

17. Lee YC, Beasley R. A year in review: Respirology 2005 - clinical science. Respirology 2006; 11: 124-30.

18. Lord SE, Rochester L, Weatherall M, McPherson KM, McNaughton HK. The effect of environment and task on gait parameters after stroke: A randomized comparison of measurement conditions. Arch Phys Med Rehab 2006; 87:967-73.

19. Marsh S, Aldington S, Shirtcliffe P, Weatherall M, Beasley R. Smoking and COPD: what really are the risks? Eur Respir J 2006; 28: 883-4.

20. Marsh S, Aldington S, Williams M, Weatherall M, Shirtcliffe P, McNaughton A, Pritchard A, Beasley R. Complete reference ranges for pulmonary function tests from a single New Zealand population. NZMJ 2006; 119(1244): U2281.

21. Marsh S, Aldington S, Williams MV, Nowitz M, Kingzett-Taylor A, Weatherall M, Shirtcliffe P, Pritchard A, Beasley R. Physiological associations of computerized tomography lung density: a factor analysis. Int J COPD 2006; 1: 181-7.

22. Masoli M, Weatherall M, Holt S, Shirtcliffe P, Beasley R. Inhaled fluticasone propionate and adrenal effects in adult asthma: systematic review and meta-analysis. Eur Respir J 2006; 28: 960-7.

23. Masoli M, Williams, M, Weatherall M, Beasley R. The 24h duration of bronchodilator action of the budesonide/formoterol combination inhaler. Respir Med 2006; 100: 20-5.

24. McCormick R, Sellman D, Robinson G. Where to next with tobacco smokers? NZMJ 2006; 119(1238): U2084.

25. McNaughton H, Kayes N, McPherson K. Interferon beta, PHARMAC, and political directives: in the best interests of people with multiple sclerosis? NZMJ 2006; 119(1232): U1939.

26. Robinson G, Aldington S, Beasley R. From medical student to junior doctor: clinical pharmacology to prescribing responsibility. StudentBMJ (January) 2006; 14: 8-9.

27. Robinson G, Aldington S, Beasley R. From medical student to junior doctor: rules of confidentiality. StudentBMJ (October) 2006; 14: 377-9.

28. Robinson G, Beasley R, Aldington S. From medical student to junior doctor: the “difficult patient”. StudentBMJ (July) 2006; 14: 278-9.

29. Robinson G, Bernau S, Aldington S, Beasley R. From medical student to junior doctor: maintaining good health during the “baptism of fire”. StudentBMJ (April) 2006; 14: 138-9.

30. Robinson G, Bernau S, Aldington S, Beasley R. From medical student to junior doctor: the night shift. StudentBMJ (November) 2006; 14: 422-4.

31. Taylor WJ, Wong A, Siegert RJ, McNaughton HK. Effectiveness of a clinical pathway for acute stroke care in a district general hospital: an audit. BMC Health Services Research 2006; 6: 16.

32. Weatherall M, Aldington S, Caldwell B, Beasley R. Inconsistencies in cardiovascular data from COX-2 inhibitor trials – is it a class effect? J R Soc Med 2006; 99: 275-6.

33. Walker P, Holt S, Timu-Parata C, Beasley R. Use of bupropion for smoking cessation. New Zealand Pharmacy 2006; 26: 32- magnesium sulphate for acute asthma: a systematic review. Chest 2005; 128: 337-44.

8. Ellwood P, Asher MI, Beasley R, Clayton TO, Stewart AW, ISAAC Steering Committee. International Study of Asthma and Allergies in Childhood (ISAAC): Phase three rationale and methods. Int J Tuberc Lung Dis 2005; 9(1): 10-6.

9. Harwood M, Aldington S, Beasley R. Lung cancer in Māori: a neglected priority. NZMJ 2005; 118(1213): U1410.

10. Holt S, Beasley R. The global burden of asthma. New Zealand Pharmacy 2005; 25: 29-31.

11. Holt S, Harwood M, Aldington S, Beasley R. PHARMAC and tobacco control in New Zealand: Government policy “up in smoke”. NZMJ 2005; 118(1216): U1502.

12. Holt S, Holt A, Weatherall M, Masoli M, Beasley R. Metered dose inhalers – a need for dose-counters. Respirology 2005; 10: 105-6.

2005

1. Aldington S, Shirtcliffe P, Weatherall M, Beasley R. Increased risk of cardiovascular events with parecoxib/valdecoxib: a systematic review and meta-analysis. NZMJ 2005; 118(1226): U1755.

2. Aldington S, Shirtcliffe P, Weatherall M, Beasley R. Systematic review and meta-analysis of the risk of major cardiovascular events with etoricoxib therapy. NZ Med J 2005; 118(1223): U1684.

3. Baker N, Holt S, Caldwell B, Beasley R. Vioxx and the COX-2 controversy. New Zealand Pharmacy 2005.

4. Beasley R, Aldington S, Robinson GM. The transition from medical student to junior doctor: how to approach the interpretation of investigations. StudentBMJ 2005; 13: 446-8.

5. Beasley R, Heuser P, Raymond N. SIT (seated immobility thromboembolism) syndrome: a 21st century lifestyle hazard. NZMJ 2005; 118(1212): U1376.

6. Beasley R, Robinson GM, Aldington S. From medical student to junior doctor: the “scripted” guide to patient clerking. StudentBMJ (November) 2005; 13: 412-3.

7. Blitz M, Blitz S, Hughes R, Diner B, Beasley R, Knopp J, Rowe BH. Aerosolized

13. Holt S, Ryder-Lewis S, Masoli M, Weatherall M, Beasley R. Fixed and adjustable dose asthma action plans based on combination therapy: a pilot study. Respirology 2005; 10: 497-503.

14. Holt S, Timu-Parata C, Ryder-Lewis S, Weatherall M, Beasley R. Efficacy of bupropion in the indigenous Māori population in New Zealand. Thorax 2005; 60: 120-3.

15. Hughes R, Thomson K, Hopkins R, Weatherall M, Wiltshire C, Wilsher M, Beasley R. Determinants of plasma D-dimer levels in a travelling population. J Thromb Haemostas 2005; 3(11): 2445-8.

16. Humbert M, Beasley R, Ayres J, Slavin R, Hébert J, Bousquet J, Beeh K-M, Ramos S, Canonica GW, Hedgecock S, Fox H, Blogg M, Surrey K. Benefits of omalizumab as add-on therapy in patients with severe persistent asthma who are inadequately controlled despite best available therapy (GINA 2002 step 4 treatment): INNOVATE. Allergy 2005; 60: 30916.

17. Masoli M, Weatherall M, Ayling J, Williams M, Beasley R. The 24 h duration of bronchodilator action of the salmeterol/ fluticasone combination inhaler. Respir Med 2005; 99: 545-52.

18. Masoli M, Weatherall M, Beasley R. Fluticasone given once versus twice a day: meta-analysis. Respirology 2005; 10: 183-8.

19. Masoli M, Weatherall M, Beasley R. Optimal starting dose of inhaled corticosteroids in adult asthma: why has it taken so long? Thorax 2005; 60: 93-4 (editorial).

20. Masoli M, Weatherall M, Holt S, Beasley R. Moderate dose inhaled corticosteroids plus salmeterol versus higher doses of inhaled corticosteroids in symptomatic asthma. Thorax 2005; 60: 730-4.

21. McNaughton H, Barber PA, Gommans J, Nowitz M. Management problems of spontaneous ICH. Hosp Med 2005; 66(4): 22934.

22. McNaughton HK, deJong G, Smout RJ, Melvin JL, Brandstater M. A comparison of stroke rehabilitation practice and outcomes between New Zealand and United States facilities. Arch Phys Med Rehabil 2005; 86(12 Suppl 2): S115-S120.

23. McNaughton HK, Weatherall M, McPherson KM. Functional measures across neurologic disease states: analysis of factors in common. Arch Phys Med Rehabil 2005; 86(11): 2184-8.

24. McNaughton HK. Traumatic Brain Injury. Evidence-Based Healthcare Bullet in 2005; (February).

25. McPherson KM, McNaughton HK. When is a stroke unit not a stroke unit? Qual Saf Health Care 2005; 14(1): 6.

26. Pendergraft TB, Stanford RH, Beasley R, Stempel DA, McLaughlin T. Seasonal variation in asthma-related hospital and intensive care unit admissions. J Asthma 2005; 42: 265-71.

27. Perrin K, Prasad S, Robinson G. Survey of the Royal Australasian College of Physicians examination candidates: preparation and impact on lifestyle. Intern Med J 2005; 35: 680-2.

28. Perrin K, Robinson P, Beasley R. Venous thromboembolism in medical inpatients — the silent epidemic of neglect [Editorial]. J R Soc Med 2005; 98: 484-5.

29. Robinson G, Narasimhan S, Weatherall M, Beasley R. Raised plasma homocysteine levels in alcoholism: increasing the risk of heart disease and dementia? NZ Med J 2005; 118(1216): U1490.

30. Weatherall M, Aldington S, Shirtcliffe P, Caldwell B, Beasley R. COX-2 inhibitors —first, do no harm. NZ Med J 2005; 118(1211): U1359.

2004

1. Beasley R, Robinson G, McNaughton A. The transition from medical student to junior doctor: an A to Z guide. BMJ Careers 2004 (31 July); 45-6 and StudentBMJ 2004 (September): 323.

2. Bramley D, Riddell T, Crengle S, Curtis E, Harwood M, Nehua D, Reid P. A call to action on Māori cardiovascular health. NZMJ 2004; 117.

3. DuMouchel W, Smith ET, Beasley R, Nelson H, Yang X, Fram D, Almenoff JS. Association of asthma therapy and ChurgStrauss syndrome: an analysis of postmarketing surveillance data. Clin Ther 2004; 26: 1092-104.

4. Foliaki S, Kildegaard Nielsen S, Björkstén B, von Mutius E, Cheng S, Pearce N, ISAAC Phase 1 Study Group. Antibiotic sales and the prevalence of symptoms of asthma, rhinitis, and eczema: the International Study of Asthma and Allergies in Childhood (ISAAC). Int J Epidemiol 2004; 33: 558-63.

5. Goldkorn A, Diotto P, Burgess C, Weatherall M, Holt S, Beasley R, Siebers R. The pulmonary and extra-pulmonary effects of highdose formoterol in COPD: A comparison with salbutamol. Respirology 2004; 9(1): 102-8.

6. Heuser P, Tonga K, Hopkins R, Henderson M, Weatherall M, Metcalfe S, Beasley R. Specific oral contraceptive use and venous thromboembolism resulting in hospital admission. NZ Med J 2004; 117(1206): U1176.

7. Holt S, Masoli M, Beasley R. Increasing compliance with inhaled corticosteroids through the use of combination therapy. [Editorial]. J Allergy Clin Immunol 2004; 113(2): 219-20.

8. Holt S, Masoli M, Beasley R. The use of the self-management plan system of care in adult asthma. Prim Care Resp J 2004; 13: 19-27.

9. Levack W, McPherson K, McNaughton H. Success in the workplace following traumatic brain injury: are we evaluating what is most important? Disabil Rehabil 2004; 26(5): 290-8.

10. Lord SE, McPherson K, McNaughton HK, Rochester L, Weatherall M. Community ambulation after stroke: how important and obtainable is it and what measures appear predictive? Arch Phys Med Rehabil 2004; 85(2): 234-9.

11. Masoli M, Beasley R. Asthma exacerbations and inhaled corticosteroids. Lancet 2004; 363: 1236.

12. Masoli M, Fabian D, Holt S, Beasley R, Global Initiative for Asthma (GINA) Program. The global burden of asthma: executive summary of the GINA Dissemination Committee report. Allergy 2004; 59: 469-78.

13. Masoli M, Holt S, Weatherall M, Beasley

R. Dose-response relationship of inhaled budesonide in adult asthma: a meta-analysis. Eur Respir J 2004; 23: 552-8.

14. Masoli M, Holt S, Weatherall M, Beasley

R. The dose-response relationship of inhaled corticosteroids in asthma. Current Allergy & Asthma Reports 2004; 4(2): 144-8.

15. Masoli M, Weatherall M, Beasley

R. Budesonide once versus twice daily administration: meta-analysis. Respirology 2004; 9: 528-34.

16. Masoli M, Weatherall M, Holt S, Beasley

R. Clinical dose-response relationship of fluticasone propionate in adults with asthma. Thorax 2004; 59: 16-20.

17. Masoli M, Weatherall M, Holt S, Beasley

R. Systematic review of the dose-response relation of inhaled fluticasone propionate. Arch Dis Child 2004; 89: 902-7.

18. McNaughton H. Doctors playing at politics. BMJ 2004; 329(7471): 925.

19. McNaughton HK. Organised stroke services. NZ Pharmacy 2004; (May): 24-7.

20. McPherson K, Myers J, Taylor WJ, McNaughton HK, Weatherall M. Self-valuation and societal valuations of health state differ with disease severity in chronic and disabling conditions. Med Care 2004; 42(11): 1143-51.

21. McPherson KM, Brander P, Taylor WJ, McNaughton HK. Consequences of stroke, arthritis and chronic pain – are there important similarities? Disabil Rehabil 2004; 26(16): 98899.

22. Narasimhan S, Robinson GM. Wellens syndrome: a combined variant. J Postgrad Med 2004; 50: 73-4.

23. Pendergraft TB, Stanford RH, Beasley R, Stempel DA, Roberts C, McLaughlin T. Rates and characteristics of intensive care unit admissions and intubations among asthmarelated hospitalizations. Ann Allergy, Asthma Immunol 2004; 93: 29-35.

24. Shirtcliffe PM, Easthope SE, Weatherall M, Beasley R. Effect of repeated intradermal injections of heat-inactivated Mycobacteirum bovis bacillus Calmette-Guérin in adult asthma. Clin Exper Allergy 2004; 34: 207-12.

25. Weiland SK, Björkstén B, Brunekreef B, Cookson WOC, von Mutius E, Strachan DP and the ISAAC Phase II Study Group. Phase II of the International Study of Asthma and Allergies in Childhood (ISAAC): rationale and methods. Eur Respir J 2004; 24: 406-12.

26. Weiland SK, Hüsing A, Strachan DP, Rzehak P, Pearce N and the ISAAC Phase One Study Group. Climate and the prevalence of symptoms of asthma, allergic rhinitis, and atopic eczema in children. Occup Environ Med 2004; 61: 609-15.

2003

1. Beasley R, Ellwood P, Asher I. International patterns of the prevalence of pediatric asthma: The ISAAC program. Pediatr Clin N Am 2003; 50: 539-53.

2. Beasley R, Heuser P, Masoli M. One name to rule them all: one name to find them – Lord of the Rings and the “seated immobility thromboembolism” (SIT) syndrome. NZMJ J 2003; 116(1177): U498.

3. Beasley R, Masoli M. Asthma in New Zealand – time to get control. NZMJ 2003; 116(1174): U434.

4. Beasley R, Raymond N, Hill S, Nowitz M, Hughes R. eThrombosis: the 21st century variant of thrombosis associated with immobility. Eur Respir J 2003; 21: 374-6.

5. Burr ML, Emberlin JC, Treu R, Cheng S, Pearce NE, ISAAC Phase One Study Group. Pollen counts in relation to the prevalence of allergic rhinoconjunctivitis, asthma and atopic eczema in the International Study of Asthma and Allergies in Childhood (ISAAC). Clin Exp Allergy 2003; 33: 1675-80.

6. Crane J, Mallol J, Beasley R, Stewart A, Asher MI on behalf of the International Study of Asthma and Allergies in Childhood (ISAAC) Phase 1 study group. Agreement between written and video questionnaires for comparing asthma symptoms on ISAAC. Eur Respir J 2003; 21: 455-61.

7. Gommans J, Barber A, McNaughton H, Hanger C, Bennett P, Spriggs D, Baskett J. Stroke rehabilitation services in New Zealand. NZMJ 2003; 116(1174): U435.

8. Greenslade E, Beasley R, Jennings L, Woodward A, Weinstein P. Coxiella burnetii (Q fever) has been introduced into New Zealand. Emerging Infectious Diseases 2003; 9: 138-40.

9. Hughes R, Goldkorn A, Masoli M, Weatherall M, Burgess C, Beasley R. The use of isotonic nebulised magnesium sulphate as an adjuvant to salbutamol in the treatment of severe asthma in adults. Lancet 2003; 361: 2114-

7.

10. Hughes R, Hopkins RJ, Hill S, Weatherall M, Van de Water N, Nowitz M, Milne D, Wilsher M, Ayling J, Beasley R. Frequency of venous thromboembolism in low to moderate risk long distance air travellers: the New Zealand Air Traveller’s Thrombosis (NZATT) Study. Lancet 2003; 362: 2039-44.

11. Masoli M, Beasley R. Diagnosis and management of adult asthma. Medicine 2003; 31: 63-8.

12. Masoli M, Holt S, Beasley R. What to do at step 3 of the asthma guidelines – increase the dose of inhaled corticosteroids or add a longacting ß-agonist drug? J Allergy Clin Immunol 2003; 112: 10-2 (Editorial).

13. Masoli M, Holt S, Hughes G, Beasley R. An adult asthma assessment and management protocol for use in the emergency department. NZMJ 2003; 116: 1-7.

14. McNaughton H, McPherson K, Taylor W, Weatherall M. Relationship Between Process and Outcome in Stroke Care. Stroke 2003; 34(3): 713-7.

15. McNaughton H, McPherson K. Problems occurring late after poliomyelitis: a rehabilitation approach. Crit Rev Phys Rehabil Med 2003; 15: 295-308.

16. McPherson KM, Harwood M, McNaughton HK. Ethnicity, equity and quality: lessons from New Zealand (Nga matawaka, nga ahua tika me nga painga: nga akoranga no Aotearoa). Qual Saf Health Care 2003; 12(4): 237-

8.

17. McPherson KM, Harwood M, McNaughton HK. Ethnicity, equity, and quality: lessons from New Zealand. BMJ 2003; 327(7412): 443-4.

18. Myers JA, McPherson KM, Taylor WJ, Weatherall M, McNaughton HK. Duration of condition is unrelated to health-state valuation on the EuroQoL. Clin Rehabil 2003; 17(2): 209-15.

19. Neill AM, Wai HS, Bannan SPT, Beasley CR, Weatherall M, Campbell AJ. Humidified nasal continuous positive airway pressure in obstructive sleep apnoea. Eur Respir J 2003; 22: 258-62.

20. Shirtcliffe PM, Goldkorn A, Weatherall M, Tan PLJ, Beasley R. Pilot study of the safety and effect of intranasal delipidated and acidtreated Mycobacterium vaccae in adult asthma. Respirology 2003; 8: 497-503.

21. Watson MW, Beasley R, Holgate ST, Bardin PG. Rhinovirus is not detectable in peripheral lung tissue after asthma death. Respirology 2003; 8: 234-8.

2002

1. Beasley R, Masoli M. Evidence that current therapeutic goals have not been met in asthma. Primary Care Respiratory Journal 2002; 11(Suppl 1): S3-S6.

2. Beasley R, Page C, Lichtenstein L. Airway remodelling in asthma. Clin Exp All Rev 2002; 109-16.

3. Beasley R, Shirtcliffe P, Harper JL, Holt S, Le Gros G. Mycobacterium-based vaccines for the prevention of allergic disease – a progress report. Clin Exp Allergy 2002; 32: 1128-30 (editorial).

4. Beasley R. Management approaches to reduce asthma mortality. Proceedings of the 12th Spring Meeting of the Japanese Society of Allergology 2002; 21-9.

5. Beasley R. The burden of asthma with specific reference to the United States. J Allergy Clin Immunol 2002; 109: S482-S489.

6. Cape G S, Ivory S-J, Sellman D, Robinson G, Adams P. Evaluation of alcohol & drug education and training in NZ medical students. Focus on Health Professional Education: A Multidisciplinary Journal 2002; 4(3): 61-74.

7. Chambers G K, Day D J, Marshall S J, Robinson G M. Alcohol Dependence: Advances in understanding, diagnosis and treatment. NZ Sci Rev 2002; 59: 35-41.

8. Chambers G K, Marshall S J, Robinson G M, Maguire S, Newton-Howes J, Chong N L. The genetics of alcoholism in Polynesians: alcohol and aldehyde dehydrogenase genotypes in young men. Alcoholism: Clin & Exper Res 2002; 26: 949–55.

9. Crane J, Wickens K, Beasley R, Fitzharris P. Asthma and allergy: a worldwide problem of meanings and management? Allergy 2002; 57: 663-72.

10. Healy B, Burgess C, Siebers R, Beasley R, Weatherall M, Holt S. Do natural health food stores require regulation? NZ Med J 2002; 115: U165.

11. Hill S, Hughes R, Crutch E, Phillips J, Carter J, Beasley R. D-dimer testing in the investigation of venous thromboembolism. NZ Med Lab Sci 2002; 56: 57-62.

12. Llewellin P, Sawyer G, Lewis S, Cheng S, Weatherall M, Fitzharris P, Beasley R. The relationship between FEV1 and PEF in the assessment of the severity of airways obstruction. Respirology 2002; 7: 333-7.

13. Masoli M, Hughes R, Hughes G, Beasley R. Assessment and management of acute severe asthma in adults: protocols for the emergency department. The Asthma Journal 2002; 7: 144-7.

14. McNaughton H, Harwood M. Traumatic brain injury: assessment and management. Hosp Med 2002; 63(1): 8-11.

15. McNaughton H, Weatherall M, McPherson K, Taylor W, Harwood M. The comparability of community outcomes for European and non-European survivors of stroke in New Zealand. NZMJ 2002; 115(1149): 98-100.

16. McNaughton H, Weatherall M, McPherson K, Taylor W, Harwood M. The comparability of resource utilisation for Europeans and non-Europeans following stroke in New Zealand. NZMJ 2002; 115(1149): 101-3.

17. McNaughton H. Lowering lipids after a stroke or transient ischaemic attack. Hosp Med 2002; 63: 88-91.

18. Mitchell EA, Stewart AW on behalf of the ISAAC Phase One Study Group. The ecological relationship of tobacco smoking to the prevalence of symptoms of asthma and other atopic diseases in children: The International Study of Asthma and Allergies in Childhood (ISAAC). Eur J Epidemiol 2002; 17: 667-73.

19. Shirtcliffe P, Weatherall M, Beasley R on behalf of the ISAAC Phase One Study Group. An inverse correlation between estimated tuberculosis notification rates and asthma symptoms. Respirology 2002; 7: 153-5.

20. Tobias M, Cheung J, McNaughton H. Modelling the impact of stroke in New Zealand. Public Health Intelligence Bulletin. Wellington, 2002.

21. Yee B, Campbell A, Beasley R, Neill A. Sleep disorders: a potential role in New Zealand motor vehicle accidents. Int Med J 2002; 32: 297-304.

BOOKS, CHAPTERS & REPORTS

1. Aldington S, Beasley R. The definition and diagnosis of asthma. In: Asthma: An Atlas of Investigation and Management. Reid P (ed). Clinical Publishing: London 2006.

2. Baskett JJ, McNaughton H (eds). New Zealand Stroke Guideline 2003. Ministry of Health, Wellington.

3. Beasley R, Wijesinghe M, Perrin K. Epidemiology of asthma mortality. In: Allergy Frontiers: Epigenetics, Allergens and Risk Factors. Pawankar R, Holgate ST, Rosenwasser LJ (Eds). Tokyo: Springer 2009. pp 107-122.

4. Beasley R, Douwes J, Pekkanen J, Pearce NE. How much asthma can be attributed to atopic sensitization? In: Asthma: Critical Debates. Johnston SL, Holgate ST (eds). London: Blackwell Science 2002; 35-45.

5. Beasley R, Town I, Fitzharris P. Diagnosis and assessment of asthma. In: Respiratory Medicine 3rd Edition, Volume 2, Gibson GJ, Geddes DM, Costabel U, Sterk PJ, Corrin B (eds). Elsevier Science Limited 2003; pp 1306-22.

6. Chancellor AW, McNaughton H. Motor Neurone disease, spinal cord and back problems. In Lancet Handbook of Clinical Neurology. Ed CPW Warlow. Lancet Publications 2005.

7. Fingleton J, Beasley R. Individualised treatment for asthma. In: Advances in Asthma Management. 2012 Future Medicine Ltd; 156-166.

8. Holgate S, Beasley R (eds). The Royal Society of Medicine - Your Guide to Asthma. Hodder Arnold 2005; 125p.

9. Holt S, Beasley R. The Burden of Asthma in New Zealand. Asthma & Respiratory Foundation of New Zealand Inc and Medical Research Institute of New Zealand. Auckland: Adis International Ltd 2002; p 48.

10. Holt S. Miracle Pill. Will You Take the PolyPill? Published by Random House New Zealand, 2009 (ISBN 978-1-877408-15-1).

11. Masoli M, Fabian D, Holt S, Beasley R. NHLBI/WHO Workshop Report: Global Strategy for Asthma Management and Prevention. Global Initiative for Asthma (GINA) 2004. P119.

12. Masoli M, Holt S, Weatherall M, Shirtcliffe P, Beasley R. Inhaled corticosteroid therapy in the management of asthma in adults. In: Li JT (ed). The Pharmacotherapy of Asthma. New York: Taylor & Francis Group 2006; Volume 212: 83-115.

13. McNaughton H, Gommans J (eds). Preventing Stroke. Stroke Foundation of New Zealand, 2nd ed 2004.

14. McNaughton H, Gommans J (eds). Stress and Stroke. Stroke Foundation of New Zealand, 2nd ed 2004.

15. McNaughton H, Gommans J (eds). Understanding Stroke. Stroke Foundation of New Zealand, 2nd ed 2004.

16. McNaughton H, Gommans J (eds). Understanding Transient Ischaemic Attacks. Stroke Foundation of New Zealand, Wellington 2003.

17. McNaughton H. Management of Back pain. In: Evidence-based Neurology. Eds Candelisa, Warlow. Blackwell 2005.

18. Roberts PR. Snakes and Ladders: the pursuit of a safety culture in New Zealand public hospitals. Institute of Policy Studies and Health Services Research Centre, June 2003, 185pp.

19 Robinson GM. Contribution to Chapters 6 (Opioids), 7 (Alcohol) and 11 (Sedative–Hypnotics). In: Management of Alcohol and Drug Problems. Hulse G, White J, Cape G (eds). Oxford University Press 2002. ISBN 0 19 551331 2.

20. Shirtcliffe P, Beasley R. The global burden of asthma. In: Public Health in the 21st Century. Vol 2: Disease Management. Ed. Madelon L. Finkel. Santa Barbara, CA: Praeger Publishing 2011. 99-116.

21. Travers J, Marsh S, Shirtcliffe P, Beasley R. External validity of pharmaceutical trials in asthma and chronic obstructive pulmonary disease. In: Treating Individuals: from randomised trials to personalised medicine in routine practice Rothwell PM (ed). Elsevier Ltd 2007, pp 131-5.

Awards

2001

Health Research Council of New Zealand Clinical Training Fellowship, Matire Harwood

World Lung Health Award, American Thoracic Society, Richard Beasley

2002

European Respiratory Society Research Fellowship, Rodney Hughes

2006

John McLeod Award, Hauora Māori Scholarship, Ministry of Health, Matire Harwood

Excellence in Postgraduate Study Hauora Māori Scholarship, Ministry Health, Matire Harwood

2007

Health Research Council of New Zealand Clinical Training Fellowship, Kyle Perrin

2008

Ministry of Health Hauora Māori Fellowship, Matire Harwood

Companion, New Zealand Order of Merit, Richard Beasley

2009

Health Research Council of New Zealand

Clinical Training Fellowship, Sally Eyers

2010

Asia Pacific Society of Respirology Woolcock Research Medal, Richard Beasley

Royal College of Physicians of Ireland James Smiley Lecture Medal, Richard Beasley

2011

Royal Australasian College of Physicians

John Sands Medal, Geoffrey Robinson

2012

Health Research Council of New Zealand

Clinical Training Fellowship, Janine Pilcher

2013

Asthma Australia National Award, Richard Beasley

Victoria University Wellington Miller Prize for Clinical Research, Janine Pilcher

2014

Royal Australasian College of Physicians 75th Anniversary Award, Geoffrey Robinson

Health Research Council of New Zealand

Clinical Training Fellowship, Irene Braithwaite

2015

Thoracic Society of Australia & New Zealand Research Medal, Richard Beasley

2016

Medicines New Zealand, Value of Medicines Research Award, Paul Young

Health Research Council of New Zealand

Liley Medal, Paul Young

Overall Winner New Zealand Ministry of Health Volunteer Award, Amanda McNaughton

Ministry of Health Community or NGO Health Service Team Award, Amanda McNaughton

Health Research Council of New Zealand Clinical Training Fellowship, Vivian Fu

Health Research Council of New Zealand Clinical Training Fellowship, Steven McKinstry

Star Research Achievement Award, Society of Critical Care Medicine, Rachael Parke

Senior Fellowship, Green Lane Research and Educational Fund Board, Rachael Parke

Finalist UoA/HRC 25th Anniversary Emerging Researcher Award, Matire Harwood

Sir Charles Hercus Medal, Royal Society of New Zealand, Richard Beasley

GINA Ambassador Award, Richard Beasley

2017

Health Research Council of New Zealand Clinical Training Fellowship, Paul Young

Marire Goodall Award, Te Ohu Rata a Aotearoa Māori Medical Practitioners, Matire Harwood

Te Tohu Hautoa – Courageous Leadership Award, National Hauora Coalition, Matire Harwood

L’Oréal UNESCO New Zealand For Women In Science Fellowship, Matire Harwood

Officer, New Zealand Order of Merit, Geoffrey Robinson

Health Research Council of New Zealand Clinical Training Fellowship, Diane Mackle

2018

The Beaven Medal, Health Research Council of New Zealand, Colin McArthur

100 Māori Leaders, Te Rau Matatini, Matire Harwood

Matariki Award, Tūhono for Improving Māori Health, Mana Tū, Auckland District Health Board, Matire Harwood

2019

The Beaven Medal, Health Research Council of New Zealand, Richard Beasley

The Asia Pacific Society of Respirology Medal, Richard Beasley

The University of Auckland Early Career Research Excellence Award, Rachael Parke

Te Tohu Rapuora, Leadership and contribution to Māori health research, Health Research Council and Royal Society of New Zealand, Matire Harwood

Excellence in Equity, Health Excellence Awards, Waitematā District Health Board, Matire Harwood

Health Research Council of New Zealand Clinical Training Fellowship, Karen Oldfield

Auckland District Health Board Peter Black Prize for medical research, Tom Hills

2020

Australian Clinical Trials Alliance Finalist for the Trial of the Year Award, MRINZ

Health Research Council of New Zealand Liley Medal, Mark Weatherall and Mark Holliday

New England Journal of Medicine most notable article award, Diane Mackle and Paul Young

2021

Australian Clinical Trials Alliance statistics award and runner up for the ACTA Trial of the Year award, MRINZ

Australian Clinical Trials Alliance Co-winner of the Trial of the Year, MRINZ

Australian Clinical Trials Alliance Trial of the Year Commendation, and the Excellence in Statistics Commendation, MRINZ

2022

Australian Clinical Trials Alliance Trial of the Year Award, MRINZ

2022 / 2023 SUMMER INTERNS

Higher Education

We provide practical clinical research experience and training opportunities which can contribute to, or form the entirety of higher education study including PhD, MD, Masters, and Diploma postgraduate degrees. This is made possible by close ties with our collaborative partners.

MRINZ MEDICAL DOCTORATE (MD) DEGREE

We are proud to be authorised by the New Zealand Qualifications Authority (NZQA) to award our own Medical Doctorate (MD) degree.

Internships

We lead a ten-week internship programme where students work alongside one or more of our clinical research teams, and are integrally involved in completing, presenting and publishing research projects.