100 Inventors Who Made History

Page 110

Antibiotics

gs are one of these wonder dru portant weapons medicine’s most im st disease-causing in the fight again first antibiotic was bacteria. But the ly by accident. discovered entire

eir tracks th in S E S A E IS D g in p p Sto

Florey and Chain Fleming had chanced upon the first antibiotic, but isolating penicillin in quantities large enough to treat people took more than a decade. A team in Oxford, England, led by Australian scientist Howard Florey used hospital bedpans and cow-milking equipment to produce enough penicillin to run medical trials on humans in 1941. They proved successful in fighting a range of infections and diseases.

Ernst Chain proved penicillin’s success in fighting bacteria in mammals through experiments with mice.

By the way...

I was a key member of Howard Florey’s team. Along with Florey and Alexander Fleming, I was awarded the 1945 Nobel Prize for Medicine.

Fleming’s fluke By the 19th century, scientists had figured out that many diseases are caused by microscopic living things called bacteria. In 1928, Scottish bacteriologist alexander Fleming noticed that one of his petri dishes containing Staphylococcus bacteria had become contaminated with a blue mold, which seemed to have wiped out the bacteria. Fleming realized that the mold contained a bacteria-killing chemical, which he called penicillin.

It paved the way fo r... Streptomycin was first made in 1943 by American scientist Selman WakSman from bacteria found in soil. It was the first antibiotic remedy for tuberculosis.

108

tetracycline was first discovered in 1945 and then made in labs by American drug company Pfizer in the early 1950s. It became the moSt preScribed antibiotic in the United States.


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Acknowledgments

10min
page 130

Index

2min
page 129

Glossary

3min
page 128

Fantastic future

5min
pages 126-127

Total turkeys

5min
pages 124-125

Micro machines

2min
pages 122-123

Bionic body parts

2min
pages 120-121

Vaccination

2min
pages 118-119

Defibrillator

0
page 117

Aspirin

1min
page 116

Diagnostic devices

2min
pages 114-115

Laser

0
page 113

Microscope

1min
page 112

Antibiotics

2min
pages 110-111

Antiseptics

1min
page 109

Chocolate

2min
pages 104-107

Anesthetics

1min
page 108

Fireworks

2min
pages 102-103

Movies

2min
pages 100-101

Personal stereo

1min
page 99

Musical instruments

2min
pages 96-97

Video games

1min
page 98

Sports shoes

1min
page 95

Desk buddies

1min
pages 92-93

Blue jeans

1min
page 94

Robot

2min
pages 90-91

Material world

2min
pages 88-89

Dynamite

1min
page 87

Crane

1min
page 86

Plow

2min
pages 84-85

Keeping it together

2min
pages 78-81

Battery

2min
pages 76-77

Bar code

1min
page 83

Plastic

2min
pages 74-75

Money

1min
page 82

Refrigerator

2min
pages 72-73

Home helpers

1min
pages 70-71

Light bulb

2min
pages 68-69

Internet

1min
page 60

Pendulum clock

2min
pages 66-67

World Wide Web

3min
pages 61-63

Telescope

2min
pages 58-59

Flush toilet

2min
pages 64-65

Satellite

2min
pages 56-57

Computer

2min
pages 54-55

Microprocessor

1min
page 53

Braille

1min
page 41

Transistor

1min
page 52

Radio

2min
pages 46-47

Picture this

2min
pages 48-49

Television

2min
pages 50-51

Phonograph

2min
pages 42-43

Telephone

2min
pages 44-45

Telegraph

1min
page 40

Rocket

2min
pages 30-31

Printing press

2min
pages 38-39

Nuclear energy

2min
pages 32-35

Helicopter

2min
pages 28-29

Paper

2min
pages 36-37

Airplane

2min
pages 26-27

Car

2min
pages 24-25

Bicycle

2min
pages 20-21

Navigational novelties

2min
pages 14-15

Steam engine

1min
page 16

Electric motor

2min
pages 18-19

Caravel

1min
page 12

Submarine

1min
page 13

The wheel

2min
pages 10-11

Steam locomotive

1min
page 17
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