May dementia current awareness by Musgrove Park Hospital Library

Library Services Musgrove Park and Somerset Partnership

Current Awareness Dementia This monthly Current Awareness Bulletin is produced by the Library, Musgrove Park Academy to provide staff with a range of dementia-related resources to support practice. It includes recently published guidelines and research articles, news and policy items.

This guide provides a selection of resources relevant to the subject area and is not intended to be a comprehensive list. All websites have been evaluated and details are correct at the time of publications. Details correct at time of going to print. Please note that resources are continuously updated. For further help or guidance, please contact a member of library staff.

This guide has been compiled by: Jess Pawley Senior Library Assistant Musgrove Park Hospital Library Service jessica.pawley@tst.nhs.uk Issue 11 May 2016

Contents Click on a section title to navigate contents Page Results of Library Current Awareness Survey

Colleague App

Recent journal articles

Books

Cochrane Systematic Reviews

Guidelines

UpToDate & DynaMed Plus

Dementia in the News

Reports, publications and resources

Topic Alerts and Updates

Twitter

Training & Networking Opportunities, Conferences, Events

Literature search service

Training and Athens

Library contact details: Library Musgrove Park Academy Musgrove Park Hospital Taunton Somerset TA1 5DA Tel: 01823 34 (2433)

Email: library@tst.nhs.uk Blog: http://librarymph.wordpress.com @musgrovesompar

RESULTS OF LIBRARY CURRENT AWARENESS SURVEY BACK TO TOP

During 2015-6 the library team introduced a number of new current awareness bulletins as a result of feedback from staff. Along with the fortnightly Library Alert monthly updates were produced for: Dementia Stroke End of life Sign up to safety

Mentorship Cancer ITU

While we had some feedback that these bulletins were useful, we felt due to the cost in library staff time, it would be better to have more detailed evidence. We circulated the survey via email to the various email lists, added a link on the Library webpage and also put reminders in the Library Alert and Staff Bulletin. During the month when we received 211 replies on all bulletins covering both Taunton and Somerset and Somerset Partnership staff. The final report can be found here

COLLEAGUE APP BACK TO TOP The MPH Staff App has specifically been produced and designed to offer both current and future employees relevant information related to their work. Whether seeking information about policies and procedures, following us on Twitter or even taking advantage of special offers, all can be found here.

Library monthly current awareness bulletins are also available. To download, please follow this link Please note- The app has not been created by the library. If you have any problems downloading or accessing the app then you will need to contact the IT department.

RECENT JOURNAL ARTICLES BACK TO TOP This is a list of journal articles on the topic of dementia. Some articles are available in the library or on-line via an OpenAthens password by following the full-text link. If you would like an article which is not available as full-text then please contact library staff. Please note that abstracts are not always available for all articles. Title: Living positively with dementia: a systematic review and synthesis of the qualitative literature. Citation: Aging & mental health, Jul 2016, vol. 20, no. 7, p. 676-699, 1364-6915 (July 2016) Author(s): Wolverson, E L, Clarke, C, Moniz-Cook, E D Abstract: Little is known about how and to what extent people with dementia live positively with their condition. This study aimed to review and carry out a synthesis of qualitative studies where accounts of the subjective experiences of people with dementia contained evidence of positive states, experiences or attributes. A meta-synthesis was undertaken to generate an integrated and interpretive account of the ability of people with dementia to have positive experiences. A methodological quality assessment was undertaken to maximize the reliability and validity of this synthesis and to contextualize the findings with regard to methodological constraints and epistemological concepts. Twenty-seven papers were included. Three super-ordinate themes relating to positive experiences and attributes were identified, each with varying and complementing sub-themes. The first superordinate theme related to the experience of engaging with life in ageing rather than explicitly to living with dementia. The second theme related to engaging with dementia itself and comprised the strengths that people can utilize in facing and fighting the condition. The third theme captured how people with dementia might transcend the condition and seek ways to maintain identity and even achieve personal growth. This review provides a first step towards understanding what conceptual domains might be important in defining positive outcomes for people who live with dementia. Highlighting the potential for people to have positive experiences in spite of or even because of their dementia has important implications for de-stigmatizing dementia and will enhance person-centred approaches to care. ________________________________________________________________________________ Title: The influence of individual and organizational factors on person-centred dementia care. Citation: Aging & mental health, Jul 2016, vol. 20, no. 7, p. 700-708, 1364-6915 (July 2016) Author(s): Hunter, Paulette V, Hadjistavropoulos, Thomas, Thorpe, Lilian, Lix, Lisa M, Malloy, David C Abstract: Although some individual and organizational contributors to person-centred care or quality of care have been studied, they have rarely been examined together. Our goal was to investigate the association of personal and organizational-environmental characteristics with self-reported personcentred behaviours in long-term residential care settings. We asked 109 long-term care staff from two Canadian long-term care homes to complete scales assessing self-reported person-centred care, organizational support for person-centred care, beliefs about personhood in dementia, and burnout. Independent variables included four employee

background characteristics (age, gender, occupation, and years of education), beliefs about personhood in dementia, burnout, and three aspects of organizational support for person-centred care (the physical environment of residents, collaboration on care, and support from management). Dependent variables included five aspects of person-centred care: autonomy, personhood, knowing the person, comfort care, and support for relationships .We used multiple linear regression analysis and changes in R(2) to test variable associations. Including organizational variables in regression models resulted in statistically significant (p < .05) changes in R(2) for each of the five dependent variables. Including personal variables resulted in statistically significant changes in R(2) for some dependent variables, but not others. In particular, including employee background characteristics resulted in a statistically significant change in R(2) for comfort care, and including beliefs about personhood and burnout resulted in statistically significant changes in R(2) for personhood but not for other dependent variables. Organizational characteristics are associated with several aspects of person-centred dementia care. Individual characteristics, including gender, beliefs about personhood, and burnout, appear to be more important to some aspects of person-centred dementia care (e.g., respect for personhood and comfort care) than others. ________________________________________________________________________________ Title: Certified normal: Alzheimer's disease biomarkers and normative estimates of cognitive functioning Citation: Neurobiology of Aging, July 2016, vol./is. 43/(23-33), 0197-4580;1558-1497 (July 01, 2016) Author(s): Hassenstab J., Chasse R., Grabow P., Benzinger T.L.S., Fagan A.M., Xiong C., Jasielec M., Grant E., Morris J.C. Abstract: Normative samples drawn from older populations may unintentionally include individuals with preclinical Alzheimer's disease (AD) pathology, resulting in reduced means, increased variability, and overestimation of age effects on cognitive performance. A total of 264 cognitively normal (Clinical Dementia Rating = 0) older adults were classified as biomarker negative ("Robust Normal," n = 177) or biomarker positive ("Preclinical Alzheimer's Disease" [PCAD], n = 87) based on amyloid imaging, cerebrospinal fluid biomarkers, and hippocampal volumes. PCAD participants performed worse than robust normals on nearly all cognitive measures. Removing PCAD participants from the normative sample yielded higher means and less variability on episodic memory, visuospatial ability, and executive functioning measures. These results were more pronounced in participants aged 75 years and older. Notably, removing PCAD participants from the sample significantly reduced age effects across all cognitive domains. Applying norms from the robust normal sample to a separate cohort did not improve Clinical Dementia Rating classification when using standard deviation cutoff scores. Overall, removing individuals with biomarker evidence of preclinical AD improves normative sample quality and substantially reduces age effects on cognitive performance but provides no substantive benefit for diagnostic classifications. ________________________________________________________________________________ Title: The cost-effectiveness of grip on challenging behaviour: An economic evaluation of a care programme for managing challenging behaviour Citation: International Journal of Geriatric Psychiatry, June 2016, vol./is. 31/6(567-574), 08856230;1099-1166 (01 Jun 2016) Author(s): Zwijsen S.A., Bosmans J.E., Gerritsen D.L., Pot A.M., Hertogh C.M.P.M., Smalbrugge M. Abstract: Objective The objective of the study was to evaluate the cost-effectiveness of implementing

the Grip on Challenging Behaviour care programme (GRIP) on dementia special care units in comparison with usual care. Methods A stepped wedge design was used. Challenging behaviour and quality of life were measured using the Cohen Mansfield Agitation Inventory (CMAI) and the QUALIDEM. Quality-adjusted life years (QALYs) were calculated using the EuroQol-5D. Psychoactive medication use (range 0-5 per measurement) and sick leave were registered. Costs included medication, time spent on challenging behaviour and education. Costs and effects were analysed using linear multilevel regression. Incremental cost-effectiveness ratios were calculated. Statistical uncertainty was estimated using bootstrapping. Results Seventeen dementia special care units participated. GRIP led to improvement on the QUALIDEM subscale social relations (1.6; 95% CI 0.18 to 3.4) and on the use of psychoactive medication (-0.73; 95% CI -1.1 to -0.46) and to a decrease in QALYs (-0.02; 95% CI -0.06 to -0.003). No significant effects on CMAI, sick leave and other QUALIDEM subscales were found. The intervention was not cost-effective in comparison with usual care with regard to CMAI score, QALYs and sick leave. The willingness to pay should be 320/point improvement on the QUALIDEM subscale social relations and 370/psychoactive medication less to reach a 0.95 probability of cost-effectiveness. Conclusion It depends on how much society is willing to pay whether GRIP can be considered cost-effective. Because the appropriateness of the current methods for analysing cost-effectiveness in this specific population is uncertain, the positive effects on behaviour, medication and job satisfactions should also be taken in account in the decision making. ________________________________________________________________________________ Title: Are depressive symptoms in mild cognitive impairment predictive of conversion to dementia? Citation: International psychogeriatrics / IPA, Jun 2016, vol. 28, no. 6, p. 921-928, 1741-203X (June 2016) Author(s): De Roeck, Ellen, Ponjaert-Kristoffersen, Ingrid, Bosmans, Marc, De Deyn, Peter Paul, Engelborghs, Sebastiaan, Dierckx, Eva Abstract: Depressive symptoms are common in amnestic mild cognitive impairment (aMCI). The association between depressive symptoms and conversion to dementia is not yet clear. This longitudinal study was conducted to ascertain whether depressive symptoms in aMCI patients are predictive of conversion to dementia. 35 aMCI patients participated in this study. All participants underwent cognitive testing and were administered the geriatric depression scale (GDS) to determine the presence of depressive symptoms. A score equaling or higher than 11 on the GDS was taken as the cut-off point for presence of significant depressive symptoms. Conversion to dementia was assessed at follow-up visits after 1.5, 4, and 10 years. 31.4% of the patients reported depressive symptoms at baseline. None of the cognitive measures revealed a significant difference at baseline between patients with and without depressive symptoms. After 1.5, 4, and 10 years respectively 6, 14, and 23 patients had converted to dementia. Although the GDS scores at baseline did not predict conversion to dementia, the cognitive measures and more specifically a verbal cued recall task (the memory impairment scale-plus) was a good predictor for conversion. Based on this dataset, the presence of depressive symptoms in aMCI patients is not predictive of conversion to dementia.

________________________________________________________________________________ Title: Analysis of genetics and risk factors of Alzheimer's Disease. Citation: Neuroscience, Jun 2016, vol. 325, p. 124-131, 1873-7544 (June 14, 2016) Author(s): Panpalli Ates, M, Karaman, Y, Guntekin, S, Ergun, M A Abstract: Alzheimer's Disease is the leading neurodegenerative cause of dementia. The pathogenesis is not clearly understood yet, is believed to be the complex interaction between genetic and environmental factors. Consequently vascular risk factors and Apolipoprotein E genotyping are increasingly gaining importance. This study aimed at assessing the relationships between Alzheimer's Disease and Apolipoprotein E phenotype and vascular risk factors. Patients diagnosed with "possible Alzheimer's Disease" in the Gazi University, Department of Neurology, were included in the study and age-matched volunteer patients who attended the polyclinic were included as a control group. In this study, the risk factors including low education level, smoking, hyperlipidemia, higher serum total cholesterol levels, and hyperhomocysteinemia were found to be statistically significantly more common in the Alzheimer's Disease group in comparison to the Control Group, while all Apolipoprotein E ε4/ε4 genotypes were found in the Alzheimer's Disease group. The presence of the Apolipoprotein E ε4 allele is believed to increase vascular risk factors as well as to affect Alzheimer's Disease directly. The biological indicators which are used in identifying the patients' genes will be probably used in the treatment plan of the patients in the future. ________________________________________________________________________________ Title: Association of psychological distress late in life and dementia-related mortality. Citation: Aging & mental health, Jun 2016, vol. 20, no. 6, p. 603-610, 1364-6915 (June 2016) Author(s): Rosness, Tor Atle, Strand, Bjørn Heine, Bergem, Astrid Liv Mina, Nafstad, Per, Langballe, Ellen Melbye, Engedal, Knut, Tambs, Kristian, Bjertness, Espen Abstract: It is not fully understood how subjective feelings of psychological distress prognosticate dementia. Our aim was to investigate the association between self-reported psychological distress and risk of dementia-related mortality. We included 31,043 eligible individuals between the ages of 60 and 80 years, at time of examination, from the CONOR (Cohort of Norway) database. They were followed for a period of 17.4 years (mean 11.5 years). The CONOR Mental Health Index, a seven-item self-report scale was used. A cut-off score equal to or above 2.15 on the scale denoted psychological distress. Cox regression was used to assess the association between psychological distress and risk of dementia-related mortality. Total number of registered deaths was 11,762 and 1118 (9.5%) were classified as cases of dementiarelated mortality. We found that 2501 individuals (8.1%) had psychological distress, of these, 119 (10.6%) had concomitant dementia-related mortality. Individuals with psychological distress had an increased risk of dementia-related mortality HR = 1.52 (95% confidence interval (CI) 1.25-1.85) after adjusting for age, gender and education. The association remained significant although attenuated when implemented in a full adjusted model, including general health status, smoking, obesity, hypertension, diabetes and history of cardiovascular disease; hazard ratio, HR = 1.30 (95% CI 1.061.59). Our results indicate that psychological distress in elderly individuals is associated with increased risk of dementia-related mortality. Individuals at increased risk of dementia may benefit from treatments or interventions that lessen psychological distress, but this needs to be confirmed in future clinical studies.

________________________________________________________________________________ Title: Dementia worry and its relationship to dementia exposure, psychological factors, and subjective memory concerns. Citation: Applied neuropsychology. Adult, May 2016, vol. 23, no. 3, p. 196-204, 2327-9109 (2016 May-Jun) Author(s): Kinzer, Adrianna, Suhr, Julie A Abstract: With increased societal awareness of dementia, older adults show increased concern about developing dementia, leading to misidentification of aging-related cognitive glitches as signs of dementia. While some researchers have suggested self-reported cognitive concerns accurately identify older adults with early signs of dementia, there is evidence that subjective cognitive decline is not associated with objective cognitive performance and instead reflects psychological factors consistent with models of health anxiety, including dementia worry. We examined the construct of dementia worry and its relationship to subjective memory concerns in 100 older adults (Mage = 69 years) without signs of dementia, using a recently developed measure of dementia worry. Consistent with hypotheses, dementia worry was related to exposure to dementia, having a high number of depressive or general worry symptoms, and having more memory concerns. Exposure to dementia moderated the relationship of dementia worry to depression and general worry. Furthermore, dementia worry moderated the relationship of objective memory impairment to subjective memory ratings. The results provide further evidence of the role of psychological factors such as dementia worry in subjective memory report and emphasize the need for objective cognitive testing before making determinations about dementia in older adults expressing memory concerns. ________________________________________________________________________________ Title: A spherical brain mapping of MR images for the detection of Alzheimer's disease Citation: Current Alzheimer Research, May 2016, vol./is. 13/5(575-588), 1567-2050;1875-5828 (01 May 2016) Author(s): Martinez-Murcia F.J., Gorriz J.M., Ramirez J., Ortiz A. Abstract: Magnetic Resonance Imaging (MRI) is of fundamental importance in neuroscience, providing good contrast and resolution, as well as not being considered invasive. Despite the development of newer techniques involving radiopharmaceuticals, it is still a recommended tool in Alzheimer's Disease (AD) neurological practice to assess neurodegeneration, and recent research suggests that it could reveal changes in the brain even before the symptomatology appears. In this paper we propose a method that performs a Spherical Brain Mapping, using different measures to project the three-dimensional MR brain images onto two-dimensional maps revealing statistical characteristics of the tissue. The resulting maps could be assessed visually, but also perform a significant feature reduction that will allow further supervised or unsupervised processing, reducing the computational load while maintaining a large amount of the original information. We have tested our methodology against a MRI database comprising 180 AD affected patients and 180 normal controls, where some of the mappings have revealed as an optimum strategy for the automatic processing and characterization of AD patterns, achieving up to a 90.9% of accuracy, as well as significantly reducing the computational load. Additionally, our maps allow the visual analysis and interpretation of the images, which can be of great help in the diagnosis of this and other types of dementia. ________________________________________________________________________________

Title: Modifiable risk factors for nursing home admission among individuals with high and low dementia risk. Citation: Archives of Gerontology & Geriatrics, 2016, vol./is. 65/(140-145), 01674943 Author(s): Rist, Pamela M., Nguyen, Thu T., Whitmer, Rachel A., Glymour, M. Maria ________________________________________________________________________________

BOOKS BACK TO TOP If you are unable to find a book, or require a book that is not on this list, please ask library staff who will be able to locate the book for you using interlibrary loan. Please note that some books detailed below may not be available in your local library and would need to be ordered for you. Some books from our electronic book collection- click on book cover and log in with your OpenAthens password to browse free online or to request access. Alzheimer’s and other dementias: answers at your fingertips Bailey, A th 4 edition, 2015

Dementia for dummies Atkins, S 2015

From the back of the book:

From the back of the book: Your hands-on guide to dealing with dementia within the UK healthcare system

If you are affected by dementia this book is for you. You may know or care for someone with dementia or you may have been recently diagnosed yourself. Whoever you are, confusion not only affects the person with the condition. Carers, family members and friends are all bewildered and confused by what is happening to the person they know. Often, when diagnosis is made you cannot think of all the questions you want to ask and may not even feel ready to ask them. But as time passes you will want to know as much as possible about dementia and how to care for the person who has it. Knowledge is the best way of lifting the cloud of confusion and taking charge of the situation.

If a loved one has recently been diagnosed with dementia, Dementia For Dummies, UK Edition provides trusted, no-nonsense guidance on what this may mean for you and your family. You'll get an understanding of the symptoms of dementia, make sense of the stages of the illness and grasp the differences between the various types of dementia, including Alzheimer's disease and vascular dementia. Dementia is an increasingly common condition that can have a significant impact on family life. Each person diagnosed is unique, and your loved one's symptoms can range from loss of memory to mood changes to communication problems and beyond. This sensitive, authoritative guide walks you through the different scenarios you may encounter as a family member or carer and explains step-by-step how you can keep your loved one as safe and as comfortable as possible--no matter how severe their symptoms are. 

Gives you the straight facts on dementia  the symptoms, TauntonCovers and SomPar NHS causes staff - and Have you visited the EBL eBook catalogue? risk factors of dementia Follow the links below login viatheOpenAthens to read online books free for 5-10 minutes  Helps identifyand and address fears as you face a diagnosis day, send requests for eBook loans or purchase suggestions  Provides carers and family members with the information needed to help eBook catalogue About OpenAthens manage the illness

If you're looking for support as you adjust to caring for a loved one with dementia, Dementia For Dummies helps make it easier.

each

COCHRANE SYSTEMATIC REVIEWS BACK TO TOP Reviews from April 2016 Omega-3 fatty acids for the treatment of dementia

GUIDELINES BACK TO TOP NICE Guidelines Updated Guideline CG42 Dementia: supporting people with dementia and their carers in health and social care- updated May 2016 Existing Guidelines NG22: Older people with social care needs and multiple long-term conditions- November 2015 NG16: Disability, dementia and frailty in later life- mid-life approaches to prevention- October 2015

UPTODATE & DYNAMED PLUS BACK TO TOP Whatâ&#x20AC;&#x2122;s new from our clinical decision-making tools on the topic of dementia. UpToDate Access for Musgrove Park Staff only DynaMed Plus Access for Somerset Partnership Staff only Please contact library staff for details on how to access these resources; you will need an Athens password.

DEMENTIA IN THE NEWS

BACK TO TOP Behind the Headlines UK dementia rates have fallen sharply in men Natural protein ‘restores memory in mice with Alzheimer’s’

REPORTS, PUBLICATIONS AND RESOURCES BACK TO TOP NICE Pathway on Dementia NICE Pathway on Dementia, Disability and Frailty in Later Life: Mid-Life Approaches to Delay or Prevent Onset overview SCIE (Social Care Institute for Excellence) Dementia Gateway th

10 UK Dementia Congress 2015- slides and presentations from this year’s conference Improving Dementia Education and Awareness (IDEA)- Online resource created by the University of Nottingham, listing online courses, news, events and resources. Age UK- resource and information page on dementia. DEEP- the dementia engagement and empowerment project Public Health England Dementia Profile Welcome to the dementia profile. This profile has been developed to support the work of the Dementia Intelligence Network (DIN) in providing health intelligence with which to inform the provision of care of people in England who have dementia. Communication and Alzheimer’s Alzheimer's disease and other dementias gradually diminish a person's ability to communicate. Communication with a person with Alzheimer's requires patience, understanding and good listening skills. These strategies can help both you and the person with dementia understand each other better. NIHR Dissemination Centre This highlight summarises some recent NIHR funded research in this area. This is not a definitive review of evidence relating to carers of people with dementia, but brings together NIHR research

published in the last two years which will be of particular interest to family carers and those agencies who need to support them. Brain imaging links Alzheimer's decline to tau protein Using a new imaging agent that binds to tau protein and makes it visible in positron emission tomography (PET) scans, scientists have shown that measures of tau are better markers of the cognitive decline characteristic of Alzheimer's than measures of amyloid beta seen in PET scans. Dementia and comorbidities: ensuring parity of care This report, supported by Pfizer, argues that a failure to prevent, diagnose and treat depression, diabetes and urinary tract infections in people with dementia could cost the UK's health and care system up to nearly £1 billion per year. It highlights a lack of parity in the diagnosis of these conditions in people with dementia and outlines some recommendations including revision of NICE clinical guidelines; greater patient involvement in care plans; and commissioning of a wider range of psychological therapies. Getting Along – equipping couples to live well with the presence of dementia Getting Along is a short programme that supports couples to work together to explore the impact of dementia within their relationship and to find mutual ways to overcome any presenting difficulties. The increasing call for early dementia diagnoses still leaves a gap in actual practical peri- and postdiagnostic support. The Getting Along© programme is something that not only can fill that gap, but that works too. The recent Getting Along pilot in York made a real difference in equipping couples at an early stage face up to the presence of a dementia in their midst; it can level the playing field within the relationship when one partner has an impairment; and it can go a long way to putting an end to the iniquitous and prevailing stress and burden model of care that implies blame on the person living with the condition. PRESENT – Experiences from a co-production journey with people who have dementia The final report from our co-production project PRESENT. People with dementia were asked to define issues of importance to them, set the local priorities for action and together we created solutions. This involved community cafes, connections and commitment. This report details the policy background, the process, experiences and outcomes. Dementia Carer Voices Dementia Carer Voices, managed by the Health and Social Care Alliance Scotland (the ALLIANCE) is a Scottish Government Project funded project to 2016 to engage with Health and Social Care professionals and students to promote a fuller understanding of the carer journey, provide a platform where carers can express their views and experiences of caring for a loved one with dementia. Fix Dementia Care: Care Homes Making the decision to move into a care home is an incredibly difficult one, both for the person with dementia and their carers or loved ones. What should make this decision easier is the assurance that in a care home, a person with dementia will receive the same, if not better, access to healthcare services. Yet Alzheimer's Society's latest investigation for our Fix Dementia Care campaign has revealed that this is not always the case. People Who Think Positively About Aging Less Likely to Have Alzheimer’s People who stress out about getting old are more likely to be diagnosed Alzheimer’s disease, scientists are warning. Researchers have found middle-aged people who dread their senior years are more likely to have dementia-like changes to their brain years later. On the other hand, those who think positively about their inevitable aging are less likely to be diagnosed.

How Music ‘Radically’ Improves the Brain, Dementia, and Alzheimer’s Music therapy has proven to be an extraordinary healing modality for many years now. Those fortunate individuals who have music in their life on a regular basis typically have a more positive frame of mind and emotional comportment. Truly uplifting music triggers a whole set of favorable responses from the human body and psyche. New Smartphone Game Could Help Doctors Diagnose Dementia There are games and apps for smartphones that claim to be able to help users sleep, eat properly, and train their brains, many of which have been disproven. But it appears that a new game on the iOS and Android market could help doctors diagnose patients with dementia. The game helps scientists see how the brain navigates space. Yoga, meditation may reduce dementia risk Completing a 3-month yoga and meditation course may reduce older adults' risk of mild cognitive impairment - considered a precursor for development of Alzheimer's disease and other forms of dementia. This is the conclusion of a new study published in the Journal of Alzheimer's Disease. Study contradicts belief that cancer protects against Alzheimer's Despite studies that claim people with cancer are less likely to develop Alzheimer's disease--raising the possibility that what triggers cancer also prevents the neurodegenerative disorder--a new investigation finds a more somber explanation. Many cancer patients don't live long enough to get Alzheimer's. The research, led by investigators at Huntsman Cancer Institute at the University of Utah, was published in The Journals of Gerontology: Series B. Holistic approach to mealtimes could help dementia sufferers Eating together, providing social support and interaction during meals could help people with dementia avoid dehydration and malnutrition - according to new NIHR-funded research from the University of East Anglia. Findings published reveal that while no interventions were unequivocally successful, promising approaches focused on a holistic approach to mealtimes. GPs maintain dementia diagnosis levels following pay-per-diagnosis scheme Prevalence of recorded dementia remained stable among GP patients in England throughout 2015/16, following a significant increase the year before due to a six-month incentive scheme that paid practices per diagnosis. Social clubs fill gap in dementia support Community-based social groups could play a crucial role in empowering people with early-onset dementia, according to new research. The research focused on an independently run program known as Paul's Club, which offers social and recreational activities three days a week out of a hotel in downtown Vancouver. Members range in age from mid-40s to late 60s. Potential cause of dementia to be investigated with £1m grant Stuart Pickering-Brown, Professor of Neurogenetics at The University of Manchester, has been awarded £1million from the Medical Research Council to study a common cause of dementia. Frontotemporal Lobar Degeneration (FTLD) is the second most common cause of dementia after Alzheimer's disease and is related to motor neurone disease. Around 40% of patients with FTLD have a family history of dementia, indicating that genetics plays a large role in the development of the condition. Great strides are being made in dementia awareness – Professor Alistair Burns NHS England’s National Clinical Director for Dementia marks National Dementia Awareness Week by outlining the significant progress being made in this area of care.

Dementia survey At the start of Dementia Awareness Week 2016, the Dementia Society has published the results of a survey showing that 56% of people are putting off seeking a dementia diagnosis for up to a year or more. The Alzheimer’s Society is calling on people to confront dementia, be aware that they can do something about it and go to the charity for help and support.

TOPIC ALERTS AND UPDATES BACK TO TOP ABSTRACTS AVAILABLE VIA LINKS BELOW- FOR FULL-TEXT PLEASE ASK LIBRARY STAFF

Behavioural and psychological symptoms in dementia and the challenges for family carers: systematic review The British Journal of Psychiatry (2016) 208, 429–434 FREE FULL TEXT

NHS Evidence Interventions to delay functional decline in people with dementia: a systematic review of systematic reviews BMJ Open 2016;6 FREE FULL TEXT

Elsevier Practice Updates White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the dominantly inherited Alzheimer network Annals of Neurology, April 2016, online ahead of print Effect of antidepressant treatment on cognitive impairments associated with depression: a randomised longitudinal study Lancet Psychiatry, Volume 3, No. 5, p425–435, May 2016 Diagnostic and Prognostic Utility of the Synaptic Marker Neurogranin in Alzheimer Disease JAMA Neurol. 2016;73(5):561-571

Medscape Topic Alerts Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease JAMA Neurol. Published online April 18, 2016 Patients with rosacea have increased risk of dementia Annals of Neurology, online 28 Apr 2016

10-year trajectories of depressive symptoms and risk of dementia: a population-based study Lancet Psychiatry, Published Online: 29 April 2016

TRIP Database Does admission to a specialist geriatric medicine ward lead to improvements in aspects of acute medical care for older patients with dementia? Int J Geriatr Psychiatry. 2016 May 19 [Epub ahead of print] Bapineuzumab for mild to moderate Alzheimer's disease in two global, randomized, phase 3 trials Alzheimers Res Ther. 2016 May 12;8(1):18 FREE FULL TEXT Factors influencing quality of life of elderly people with dementia and care implications: A systematic review Arch Gerontol Geriatr. 2016 Apr 30;66:23-41. Motor Vehicle Crashes and Dementia: A Population-Based Study J Am Geriatr Soc. 2016 May 12. [Epub ahead of print] Medline Plus Trajectories of Depressive Symptoms in Older Adults and Risk of Dementia JAMA Psychiatry. 2016;73(5):525-531 An individual with human immunodeficiency virus, dementia, and central nervous system amyloid deposition Alzheimerâ&#x20AC;&#x2122;s & Dementia: Diagnosis, Assessment & Disease Monitoring 4 (2016) 1-5 FREE FULL TEXT

TWITTER BACK TO TOP The latest from popular Twitter pages dedicated to dementia: Dementia UK @DementiaUK Alzheimerâ&#x20AC;&#x2122;s Society @alzheimerssoc Dementia Today @DementiaToday Dementia Friends @DementiaFriends

TRAINING & NETWORKING OPPORTUNITIES, CONFERENCES, EVENTS BACK TO TOP

Alzheimer’s Society Training and resources Dementia training for care providers Health Education England Dementia awareness training RCN Ongoing work at the RCN on dementia care

Online learning Caring for people with dementia in the general hospital – Communication http://sonet.nottingham.ac.uk/rlos/mentalhealth/communication/ Caring for people with dementia in the general hospital - Dementia and Cognitive Loss http://sonet.nottingham.ac.uk/rlos/mentalhealth/dementia_hospital/ Caring for people with dementia in the general hospital - Person-centred dementia care http://sonet.nottingham.ac.uk/rlos/mentalhealth/dementia_care/

The 2016 Alzheimer’s Disease Congress- 7 -9 June 2016, London th

4 International Conference on Vascular Dementia- 30 June-2 th

July 2016, Valencia

Alzheimer’s Association International Conference- 24 -28 July 2016, Toronto th

5 International Conference on Alzheimer’s Disease and Dementia - 29 September-1 October 2016, London th

26 Alzheimer Europe Conference- 31 October-2

November 2016, Copenhagen

LITERATURE SEARCH SERVICE BACK TO TOP Looking for the latest evidence-based research but havenâ&#x20AC;&#x2122;t got time to trawl the databases? Do you need a literature search carried out? Do you need to find evidence to support an improvement? Do you want to know how something has been done elsewhere and whether it worked?

Library staff provide a literature search service for busy clinicians who are pressed for time.

To request a search please complete and return the appropriate form, providing as much information as possible. Alternatively if you would like an assisted search training session, where we will sit down with you and go through the steps of a literature search, then please contact the library. Musgrove staff click here to access literature search form Somerset Partnership staff click here to access literature search form

TRAINING AND ATHENS BACK TO TOP Most electronic resources are available via an Athens password. You can register for this via the Library intranet page, or from home at www.swice.nhs.uk and following the link for Athens selfregistration. Please note that registering from home will take longer as it will need to be verified that you are NHS staff/student on placement. The library offers training on how to access and use Athens resources, as well as an introductory course on critical appraisal. You can book a course through the Learning and Development intranet page, or by contacting the library directly.