Active Pharmaceutical Ingredients Market 2019-2026 Global Active Pharmaceutical Ingredients Market to 2026 – Increasing demand for HPAP and Strong growth in small molecule pipeline with healthy transition rate between clinical phases The active pharmaceutical ingredient (API) of a medicine is the substance that exerts the therapeutic effect. Drugs are classified based on their origin, and synthetic drugs are the ones which are manufactured with the use of chemical, where stereochemical aspects often play a role; often only certain enantiomers have the desired biological effect. Strong growth in small molecule pipeline with healthy transition rate between clinical phases is driving the market growth The current Active Pharmaceutical Ingredients market is witnessed a significant growth in the historic due to regular product approvals for one or the other therapeutic drug market. Also, frequent approvals coupled with increased pipeline for small molecules have given a major boost the API market. For instance, there are around 5,300 molecules in the pipeline till 2016 end with an increase of about 13.9% since its previous year. Two third of the pharmaceutical pipeline drugs are registered a small-scale molecule, and in clinical development from phase I-III there are 2,100 small molecules with an increase of about 10.5% over 2015. Increasing demand for HPAPI Active Pharmaceutical Ingredient manufacturers are now focusing to differentiate themselves by developing their capabilities on High Potency APIs. These molecules have complex to synthesize and are required in small dose for therapeutic efficacy. Thus, require highly sophisticated equipment and specialized facility for smaller volume for production. Around 20-25% of New Chemical Entity (NCE) are considered to be potent and out of which one third of all drug candidates are for cancer treatment. The maximum contribution of HPAPIs are used in the developing anti-cancer drugs. In general, most of the HPAPIs are developed for branded drugs, however, the generic HPAPIs are taking lead in the market due to patent expiry, upon which most of the companies are out- sourcing for development of HPAPIs to Asia Pacific region. Asia-Pacific Active Pharmaceutical Ingredients Market will grow at higher pace during the forecast period DMI segments the Global Active Pharmaceutical Ingredients Market into – North America, South America, Europe, Asia-Pacific (APAC), and Middle East and Africa. The growth in the industry is mainly due to increasing demand for generic API or drugs in the region. Asia Pacific is the second largest region with 32% market share in global API market in 2017. Asia Pacific API market is further segmented in to China, Japan, India, Australia and rest of Asia Pacific. China is the leading market for APIs and accounted for 32% market share with in Asia Pacific API market in 2017, Followed by India and Japan with 29% and 23% market shares respectively. Favorable government support for drug development and approvals in order to increase investments also driving the market growth in the region. Small and medium companies have mainly contributed for the growth in the region. Competitive Market with Few Major Contributors
The global active pharmaceutical ingredients market has a strong foothold of TEVA and NOVARTIS. According to API industry guide, TEVA holds the industry’s largest portfolio of over 250 APIs. Dr. Reddy’s is another leading manufacturer of APIs with over 60 APIs that are used for drug manufacture, diagnostic kits, critical care and biotechnology products. Active Pharmaceutical Ingredients Market Taxonomy: By Product Type • •
Synthetic API Biotech API
By Nature Type
Generic API Innovator API
By Manufacturing Type • •
Captive Merchant
By Application • • • • • •
Cardiovascular Diabetes Oncology Neurology NSAIDS Others
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