16th Century: Xochipilli statue carved. Aztec statue depicts the Prince of Flowers decorated with 6 psychoactive plants: mushrooms, tobacco, morning glory, sinicuichi, cacahuaxochitl, and one unidentified.
1000 - 500 BCE: Central American cultures build temples to mushroom gods and carve "mushroom stones" found in Mexico & Guatamala.
Mid 1800s: Xochipilli statue discovered by Europeans in central Mexico.
1959: Albert Hofmann first publishes the synthesis of psilocybin.
1960-1961: Timory Leary and Richard Alpert begin a series of experiments with Harvard graduate students, using pure psilocybin.
1960-1977: Psilocybin is studied as a psychotherapeutic medicine through the 1960s and 1970s. FDA approved research with humans ends in 1977, not to be continued until the late 1990s.
Jul 11, 2006: Research shows psilocybin can induce mystical experiences.
Psilocybin:
A Chronological Evolution of Psychedelic Mushrooms