dolorox™ is a blend of botanical extracts that help relieve pain associated with arthritis, osteoarthritis and lower back pain. The efficacy and safety of each ingredient have been demonstrated by clinical trials. Combining different herbs in one product results in an additive effect of each active ingredient, thus improving the efficacy. Recommended Use dolorox™ is recommended to relieve pain associated with arthritis, osteoarthritis and lower back pain.
Dosage Take with water 4 capsules daily: 2 capsules in the morning and 2 capsules in the evening.
Active Ingredients
Active Ingredients (per capsule) - Harpagophytum procumbens (devil’s claw) (root extract standardized to 10% harpagosides) - Ribes nigrum (blackcurrant) (seed extract standardized 1% rutines) - Perna canaliculus (green mussel) (20% omega-3) - Salix alba (willow bark) (bark extract standardized to 1% salicin) - Tanacetum parthenium (feverfew) (standardized extract to 0.2% de parthenolide)
Devil’s Claw (Harpagophytum procumbens): Devil’s claw originates from Africa. For more than thirty years, it has been used in Germany and Switzerland to treat joint pain. It has been shown [1,2,3] that devil’s claw extracts relieve muscular and joint pain related to osteoarthritis and lower back pain. Blackcurrant (Ribes nigrum): Blackcurrant is a deciduous shrub with black berries growing in bunches. Its use to treat joint pain goes back to 1712 as the abbé Bailly de Montaran recommended this remedy for gout and rheumatic pain in one of his works. In 2001, a systematic review of clinical studies (by Cochrane Collaboration) [4] has shown that blackcurrant seed oil decreases joint tenderness and pain in people suffering from rheumatoid arthritis Green mussel (Perna canaliculus): Green mussel is a native New Zealand shellfish. Clinical studies demonstrated that its use reduces joint pain in people suffering from osteoarthritis [5,6,7]. Willow bark (Salix alba): Willow bark extracts have been used for thousands of years to treat fever and joint pain. Clinical studies [8,9,10] have demonstrated that willow bark was efficient to relieve joint pain related to osteoarthritis and arthritis. Feverfew (Tanecetum parthenium): This perennial plant with daisies like flowers has traditionally been used to treat pain and rheumatoid arthritis. A study by Pattrick et al. in 1989 demonstrated that Feverfew can increase grip strength in patient suffering from rheumatoid arthritis [11].
Caution Consult a health care practitioner prior to use if you are pregnant or breastfeeding, taking a blood thinner, have heart disease, taking anti-arrhythmic medication, or if you experience prolonged gastrointestinal discomfort. Use cautiously in patients with history of allergy or asthma due to fish or shellfish, salicylate, tannin or feverfew (Tanacetum parthenium) components. Discontinue use and consult a health care practitioner if symptoms persist after 45 days. Keep out of reach of children. Keep at room temperature (15-25°C). Do not use if security seal is broken.
20090325 – TechFiles - Dolorox ENG
References 1- Evidence-based Systematic Review of Devil’s Claw by the Natural Standard Research Collaboration. Copyright ® 2007. www.naturalstandard.com. 2- Chrubasik S, Junck H, Breitschwerdt H, et al. Effectiveness of Harpagophytum extract WS 1531 in the treatment of exacerbation of low back pain: a randomized, placebocontrolled, double- blind study. Eur J Anaesthesiol 1999;16(2):118-129. 3- Chantre P, Cappelaere A, et al. Efficacy and tolerance of Harpagophytum procumbens versus diacerhein in treatment of osteoarthritis. Phytomedicine. 2000 Jun;7(3):17783. 4- Litlle C, Parsons T, Herbal therapy for treating rheumatoid arthritis, Cochrane Database Syst. Rev. 2001: (1) : CD002948 5- S.L.M. Gibson and R.G. Gibson . The treatment of arthritis with a lipid extract of Perna canaliculus: a randomized trial. Complement Ther Med 1998;6:122-6. 6- LAU CS, CHIU PKY, CHU EMY, CHENG IYW, TANGWM, MAN RYK, HALPERN GM. Treatment of knee osteoarthritis with Lyprinol®, lipid extract of the green-lipped mussel – a doubleblind placebo-controlled study. Progress in Nutrition 2004; 6(1):17-31. 7- Cho SH, Jung YB, Seong SC, Park HB, Byun KY, Lee DC, Song EK, Son JH. Clinical efficacy and safety of Lyprinol, a patented extract from New Zealand green-lipped mussel (Perna Canaliculus) in patients with osteoarthritis of the hip and knee: Multicenter Clinical Trial with a 2-months treatment period. The Newest Medical Journal 2002; 45(5):27-33. 8- Chrubasik S, Eisenberg E, et al. Treatment of low back pain exacerbations with willow bark extract: a randomized double-blind study.Am J Med 2000 Jul;109(1):9-14. 9- Chrubasik S, Kunzel O, et al. Treatment of low back pain with a herbal or synthetic anti-rheumatic: a randomized controlled study. Willow bark extract for low back pain. Rheumatology (Oxford). 2001 10- Schmid B, Ludtke R, et al. Efficacy and tolerability of a standardized willow bark extract in patients with osteoarthritis: randomized placebo-controlled, double blind clinical trial.Phytother Res 2001 Jun;15(4):344-50. 11- Pattrick M, Heptinstall S, Doherty M. Feverfew in rheumatoid arthritis: a double blind, placebo controlled study. Ann Rheum Dis 1989;48(7):547-549.