Feb. 2021 — MD Leaf

Page 36

the ESSENTIAL issue leafnationmd.com

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CBN& sLEEP CURIO WELLNESS’ INNOVATIONS

Curio Wellness’ Good Night Pulse Released Tablets are one of the first medical Cannabis products to hit the market specifically formulated to address chronic sleep conditions. While many current products are marketed as sleep aids, it is hard to determine exactly what about a given product makes it sleep specific. Indeed, many products out there are essentially just a generic THC product with a label on it that says something sleep-related, without any real rhyme or reason as to how it targets sleep. Good Night on the other hand is not generic and has been clinically validated as a product for sleep.

Curio Wellness’ Good Night Tablets

FEB. 2021

It is definitely true that THC helps with sleep symptoms, but it also helps with all symptoms under the therapeutic umbrella of the endocannabinoid system, so for a lot of patients using sleep products, it’s hit or miss as to whether or not they feel a true drowsy effect, or just general relief that leads to a better night’s sleep overall. Since both outcomes will work for a patient to varying degrees, this discrepancy in the market hasn’t been fully sussed out.

Curio, however, did notice and came in to fill the gap with a specifically formulated product designed to do one thing, and one thing only: help you get to sleep and stay asleep. There are some sleep products that utilize CBN, a known soporific cannabinoid, or compounds like melatonin and valerian root, to snowball the entourage effect in the direction of sleep – but none of these products have done a good job at explaining the research (if any) that led them to formulate their products the way they did, which inevitably leaves the patient confused about what does and does not work for them. For example, if a patient uses one product and finds that it does improve their sleep symptoms, and their local dispensary sells out of that particular product, it becomes very difficult to match a product from another company to achieve those same effects. Or the opposite can happen, wherein a product doesn’t have anything but just a THC

dosage, in which case a patient can choose virtually any product in the same dosage range/ product category for the cheapest price, eventually leading to a decline in overall quality in the market. The truth of the matter is that we all must develop our own Cannabis regimens catered to our own personal biochemical needs, and that has a lot to do with the product formulation itself, the dosage of the product, the tolerance and lifestyle of the patient, and the nuances of sleep-related disorders themselves. Curio has addressed these gaps in knowledge with their Good Night Tablets in two major ways. First, they utilize Pulse Release Technology that allows for targeted dosages at targeted times to interact with the patient’s system, and second, they base all their formulation off independent third party sleep studies that mimic a clinical trial. Curio relied on data around specific cannabinoid formulation ratios in relation to their target patient demographic, and specifically to the symptoms they intend to target, to provide a true sleep aid based on the latest Cannabis research, as well as their own independent third party research study. The company partnered with SleepScore Labs to conduct an observational sleep study with 35 certified Maryland medical Cannabis patients with sleep disorders and their new Good Night Tablets. Their formulation is a 2:1 THC:CBN ratio with each tablet containing 10mg THC and 5mg CBN.


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