August 2017 Innovate E-Magazine by Oklahoma Health Center Foundation

August 2017

INNOVATE University Hospitals Authority & Trust and OU Partner to Create OU Medicine, Inc.

A publication of the Oklahoma Health Center Foundation

The Oklahoma Health Center

Welcome to our green publication, Innovate. This communication tool is brought to you by the Oklahoma Health Center Foundation to promote the happenings at the Oklahoma Health Center and bring you the latest information about our member organizations. Since 2000, more than $534 million in construction costs has been invested on the campus. In 2016, the OHC employee and OUHSC student count is approximately 18,000 making it one of the largest employers in Oklahoma. The Oklahoma Health Center is the premier address for research, patient care, education, technology and community health support. Located conveniently in the heart of Oklahoma City, this remarkable 325-acre complex unites 22 organizations ranging from cutting-edge biotechnology companies to government, education, patient care and community support institutions. As the second largest concentration of employees in Oklahoma, this health care consortium touts a $3 billion capital infrastucture that is continually growing to meet the needs and demands of the people. A recent study determined the Oklahoma Health Center has a more than $3 billion annual economic impact on the community.

800 N. Research Parkway, Suite 400 Oklahoma City, OK 73104 Phone: (405) 271-2200 Website: www.oklahomahealthcenter.com Follow Us on Facebook and Twitter @OKHealthCtr

INSIDE UHAT and OU Announce Partnership

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Speakers Announced for Oklahoma Health Center Annual Breakfast Sept. 6

Q&A with Paul L. DeAngelis: OU professor doubles as biotech entrepreneur

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Next Mind Meld September 7

16 Oklahoma Health Center Campus Map

OHCF Members

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UHAT and OU Partner to Create OU Medicine, Inc. From the office of the OUHSC Senior Vice President and Provost Jason Sanders, M.D., concerning the new partnership: The University Hospitals Authority and Trust (UHAT) and the University of Oklahoma (OU) have partnered in the creation of a new Oklahoma non-profit entity, OU Medicine, Inc., which will assume ownership and management of OU Medical System hospitals from their current operator, Hospital Corporation of America (HCA), an investor-owned company based in Nashville. OU Medicine is in the process of acquiring HCA’s financial interests in OU Medical System and intends to conclude the transaction this fall. HCA will contract to provide certain transitional and supporting health care services, but OU Medicine will assume day-to-day management responsibilities. The health system’s gov-

erning board will include representatives from UHAT, OU and the community. We are approaching a new chapter for our enterprise with tremendous promise for our patients and the quality of life of all Oklahomans. Profits from the newly formed organization will be kept here in Oklahoma and reinvested in the highest quality patient care, new treatments and cures, and expanded training of future physicians, nurses, and other critical health professionals. The health system’s mission will continue to be leading health care in patient care, education and research, and the latest actions will help us fulfill and advance that important responsibility.

Innovation to Reality: Building Successful Business Models at the Oklahoma Health Center The Greater Oklahoma City Chamber will join the Oklahoma Health Center Foundation in showcasing the Oklahoma Health Center's contributions to the latest in health-related, scientific discovery during the annual Oklahoma Health Center Breakfast. Speakers will include some of Oklahoma's foremost voices in the areas in the medical and research communities. Moderators are Rhonda Hooper, president & CEO, Jordan Advertising; Chair, Greater Oklahoma City Chamber, OHCF Board Member, and Carol Troy, OHCF Board member. Panelists: Scott Meacham President and CEO, i2E, Inc. Meacham holds a bachelor’s degree in finance, an MBA and a law degree, all from the University of Oklahoma. As President and CEO, Scott Meacham leads i2E’s efforts to create knowledge-based jobs in Oklahoma through the development of and investment in high growth companies. He served as the 17th State Treasurer of Oklahoma, an office he held from June 2005 until January 2011. He also served on the governor’s cabinet as Secretary for Finance and Revenue from January 2003 until January 2011. He currently serves on the board of directors for the State Chamber of Oklahoma. He also serves on the board of trustees and the Investment Committee of the University of Oklahoma Foundation and on the Governor’s Science and Technology Council. Paul DeAngelis, Ph.D. Professor, Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center Biotech ventures: caissonbiotech.com, heparinex.com, hyalose.com and choncept.com Dr. DeAngelis holds a Harvard College bachelor’s in biochemical sciences and a doctorate in biological sciences from the University of California-Irvine. He has postdoctoral work in biochemistry and molecular biology at University of Texas-Galveston. Dr. DeAngelis serves as chief scientist and helped found four-biotech companies. He has been a glycobiology researcher since 1981 in the fields of carbohydrate/protein interaction and polysaccharide biosynthesis using the experimental tools of molecular biology, enzyme biochemis-

September 6, 2017 7:30 am - 9:00 am

Embassy Suites Oklahoma City Downtown / Medical Center, 741 N. Phillips Ave., Oklahoma City, OK 73104

Tables of ten are available for $600. For more information on individual tickets or purchasing a table, email register@okcchamber.com.

try, and carbohydrate analysis. His overall basic science goal is to understand the fundamental mechanisms of naturally occurring enzymes. As a result of this work, sugar synthesis was vastly improved with respect to speed, controllability, and purity. Craig Shimasaki, Ph.D., MBA President, CEO and Co-Founder of Moleculera Labs, Inc. CEO and Founder of Biosource Consulting Group University of Oklahoma, Price School of Business, Entrepreneur-in-Residence, and Adjunct Professor Dr. Shimasaki received his B.S. in Biochemistry from the University of California at Davis and his Ph.D. in Molecular Biology and Biotechnology from the University of Tulsa and his M.B.A. from Northwestern University’s Kellogg School of Business. He has over 30 years of practical experience in the biotechnology industry and as a serial entrepreneur and cofounder of three biotech companies. Within these companies he has held a variety of positions, including CEO, Chief Operating Officer, Vice President of Operations, Executive VP of Research and Director of Project Planning. He has raised multiple rounds of capital, both private and public and has been involved in most every facet of a biotech start-up. 5

Q&A with Paul L. DeAngelis: OU professor doubles as biotech entrepreneur

From the Oklahoman By Paula Burkes Photo by Steve Sisney

It was a tiny advertisement in the corner of a crowded bulletin board at Harvard College that fortuitously sent Paul DeAngelis, a professor and scientist at the University of Oklahoma, on his career path of studying sugar polymers — and the now real potential for a much safer and more effective form of the blood-thinner heparin, better delivery methods for all drugs, and more. The year was 1981 and DeAngelis was a sophomore looking for a work/study job when he spied the scrap of paper about research involving carbohydrate chemistry. Most of the other research was on proteins or DNA regulation. “That work/study job is what started me off in the sugar world,” DeAngelis said. “I figured it was a new frontier and I could blaze my own trail.” And blaze he has. Along with teaching at OU, DeAngelis serves as chief scientist for four biotech companies including 15-yearold Heparinex, which produces a synthetic bacteriabased anticoagulant, after animal-based heparin caused nearly 100 deaths in China, and 8-year-old Caisson Biotech, which uses a precursor to heparin — a sugar molecule native to the human body — for a new drug delivery method that lengthens drugs’ effectiveness and lessens their side effects. From his eighth-floor lab in the OU Medicine tower, DeAngelis, 55, sat down on Tuesday to talk with The Oklahoman about his life and career. This is an edited transcript: Q: Based on your surname, I’m guessing you have Italian roots? A: Yes. My dad was 100 percent Italian. My mom is German and Irish. All of my grandparents were born in the U.S. Funny … once when I was visiting Sorrento, Italy, three different people mistook me as a native, inviting me to go somewhere or asking for a ride. I don’t speak Italian; only the Spanish I learned in high school. Q: What did your parents do? A: When they met, my mom was a jockey and my dad was a trainer. But when it was time for me to start school, my dad got a job in a brewery bottling plant in Baltimore and my mom took care of us kids. I’m the oldest of five. After we all graduated high school, my parents moved out of the city to raise thoroughbreds. My mom, who’s in her 70s, rode horses on the training track until 10 years ago. She still lives in Maryland; we’ve lost my dad. My siblings are scattered, but we all got together this past Easter at my sister’s house in Florida.

Q: When did you decide to become a scientist? A: I always liked science. As a kid, I grew plants and did experiments. My mom would say “Don’t make that smelly stuff in my kitchen,” but she was really supportive. My parents, so that we’d be physically fit, also encouraged sports. I played three or four a year, including football and wrestling. In the spring, I’d ride my bike from lacrosse practice to baseball practice. Q: Did you get a full scholarship to Harvard? A: Pretty much. Every year, I had to earn $1,000, my parents would pay $1,000, and I’d take out a $1,000 student loan. I’m sure my parents were happy, because I easily could’ve eaten more than 1,000 bucks of food a year. Q: What brought you to Oklahoma? A: I did postdoctoral work at the University of Texas medical branch in Galveston with Paul Weigel, who recruited me here after he became chair of the Biochemistry and Microbiology Department; he’s now chair emeritus. I joined the faculty in December 1994 as an assistant professor with my own projects. I’d never even driven through Oklahoma, but I knew it was a good opportunity. There already was glycobiology experience in Oklahoma, OU was proactive with biotech ventures, and people here are nice and work hard. Q: Tell us more about your promising pharmaceuticals. A: We discovered an enzyme in bacteria and harnessed the ability to make new and different-sized sugar polymers with repeating chains. That’s opened up all sorts of possibilities for biomaterials and drug delivery; much like plastics, which includes plastic bags, plastic tubes and more. One of the biotech companies I founded, Hyalose LLC, is focused on the commercialization of unique recombinant technologies for producing Hyaluronic Acid, an important biomolecule for many health care and cosmetic applications. Everything still is under evaluation, but hopefully will get into humans some time. Carbohydrates are more invisible and harder to study than proteins and DNA, which are easier to watch. There are fewer tools in the field, but we’re learning new stuff all the time. PERSONALLY SPEAKING Position: University of Oklahoma, professor of biochemistry and molecular biology. Biotech ventures: caissonbiotech.com, heparinex.com, (Continued on page 40) 7

Findings yield new clues to

Photo above: OMRF scientist and coleader of the project, Christopher Lessard, Ph.D. Photo right: OMRF scientist Kathy Sivils, Ph.D.

puzzling autoimmune disease Led by researchers at the Oklahoma Medical Research Foundation, an international coalition of scientists and physicians has discovered a new genetic risk factor that may predispose certain individuals to a debilitating condition known as Sjögren’s syndrome. Sjögren’s is an “autoimmune” disease, a family of illnesses in which the body destroys its own cells. In Sjögren’s, immune cells attack moisture-producing glands, leading to painful dryness and decreased ability to produce tears or saliva. The disease may affect as many as 4 million Americans, according to the Sjögren’s Syndrome Foundation. Common symptoms include severe dry eyes and dry mouth, as well as fatigue, arthritis and memory problems. While its causes are not fully understood, environmental triggers, such as viral infections, are believed to contribute to the development of Sjögren’s in individuals who carry certain genetic risk factors for the disease. In this new study, OMRF scientist Kathy Sivils, Ph.D. and her colleagues identified a strong association between a variant in a gene called OAS1 and susceptibility to Sjögren’s. This variant may provide valuable insight into the genetic basis of Sjögren’s, as well as other autoimmune conditions with similar triggers. “This gene was of particular interest to us, because it plays a major role in how individuals respond to viral infections. Previous studies had shown that if a person carries this variant, they may be more susceptible to certain viruses like West Nile and hepatitis C,” said Sivils. “There was very little evidence for a connection to autoimmune disease prior to our study. Firmly establishing this new association with Sjögren’s then led us to look at the gene’s function in more detail,” said OMRF scientist and co-leader of the project, Christopher Lessard, Ph.D. Scientists found that individuals with this genetic variant produce alternative forms of OAS1 that appear to lose normal function, said Sivils, and that can result in an increased susceptibility to viruses, as well as diseases like Sjögren’s. The discovery could allow researchers to test for the variant to identify people at higher risk for the disease.

“If we can get out ahead of the disease, it might help lessen the severe damage that can occur in salivary glands and other organs,” Sivils said. “Early diagnosis and proper treatment are crucial, and discoveries like this one may give researchers and healthcare professionals more to work with as they look for clues to this perplexing disease.” Sivils conducted the research as part of larger coalition known as the Sjogren’s Genetics Network, or SGENE. The network includes more than 60 scientists and physicians from the U.S., England, France, Norway, Sweden, Germany, Colombia, the Philippines and Australia. The findings were published in the journal PLOS Genetics. “On behalf of Sjögren’s patients, the Sjögren’s Syndrome Foundation applauds OMRF for its commitment to finding the many unanswered questions about the disease,” said SSF CEO Steven Taylor. “Drs. Sivils and Lessard, along with their OMRF colleagues, continue to leave their mark in advancing Sjögren’s research, and patients worldwide will benefit from their hard work.” Other OMRF researchers who contributed to the findings were He Li, Ph.D., Astrid Rasmussen, M.D., Hal Scofield, M.D., Judith James, M.D., Ph.D., Darise Farris, Ph.D., Patrick Gaffney, M.D., Courtney Montgomery, Ph.D., Susan Kovats, Ph.D., Indra Adrianto, Ph.D., Joel Guthridge, Ph.D., Ph.D., John Ice, M.D., Tove Reksten, Jennifer Kelly, Kiely Grundahl, Stuart Glenn, Adam Adler and Sean Turner. National Institutes of Health grants that contributed to this research include P50 AR0608040, 1R01 AR065953, 5RC2 AR058959 and 5P30 AR053482 from the National Institute of Arthritis and Musculoskeletal and Skin Disease; 5R01 DE015223, 1R01 DE018209 and

(Continued on page 40) 9

Stephenson Cancer Center Director Elected Chair of National Cancer Clinical Trials Organization Stephenson Cancer Center Director Robert S. Mannel, MD has been elected to serve as one of three Co-Chairs for NRG Oncology, one of four national non-profit organizations that make up the adult National Clinical Trials Network (NCTN) for the National Cancer Institute (NCI). The NCTN, the world’s premier network for developing and conducting clinical trials to advance new cancer therapies, is composed of over 2,000 institutions nationwide. NRG Oncology is the largest group within the Network, placing more cancer patients on NCI clinical trials than any other organization. “It is a tremendous honor to serve as Chair of NRG Oncology,” Mannel said. “I look forward to working with colleagues at institutions across the country and internationally to help improve the lives of cancer patients through conducting practice-changing, multi-institutional clinical and translational research.” Mannel is the Rainbolt Family Endowed Chair in Cancer and Professor of Obstetrics and Gynecology in the OU College of Medicine. He holds the position of Associate Vice Provost for Cancer Programs at the OU Health Sciences Center. Since 2006, Mannel has served as Director of the Stephenson Cancer Center. Under his leadership the Cancer Center has developed into an organization recognized nationally for its outstanding clinical and research programs. During his tenure, the Cancer Center has recruited more than 70 oncology physicians and cancer researchers to Oklahoma, and out-of-state cancer research grant funding has more than tripled during this time. In 2014, the Cancer Center was designated a Lead Participating Site in the NCTN, and it is among the top two cancer centers in the nation for the number of patients participating in NCI-funded clinical trials for new cancer treatments. “Dr. Mannel’s election to this prestigious leadership position underscores the commitment that both he and the Stephenson Cancer Center have to improving cancer patient outcomes through conducting high-quality clinical trials research,” stated Jason Sanders, MD, MBA, Senior Vice President and Provost, OU Health Sciences Center. 10

Stephenson Cancer Center Director Robert S. Mannel, MD

ABOUT NRG ONCOLOGY NRG Oncology brings together the unique and complementary research areas of the National Surgical Adjuvant Breast and Bowel Project (NSABP), the Radiation Therapy Oncology Group (RTOG), and the Gynecologic Oncology Group (GOG). NRG Oncology builds upon our more than 150 years of cumulative research experience to conduct practice defining, multi-institutional clinical trials resulting in the improved survival and quality of life of patients with cancer. NRG Oncology includes in its leadership and scientific committees internationally recognized investigators who bring extensive experience in the conduct of trials in the United States, Canada and overseas. Every NCI-designated cancer center in the United States that conducts clinical research and every lead provincial cancer center in Canada participate in NRG Oncology clinical research.

OU Leader Contributes to New National Guidelines on Surgical Infections Surgical site infections are the most common and expensive form of hospital-acquired infections, and they occur in 2 percent to 5 percent of all operations in the United States. However, at least 50 percent of such infections are preventable. An OU Medicine physician leader is among the primary authors of a new study about prevention of surgical site infections. The results of that study led to new guidelines issued by the Centers for Disease Control. Dale Bratzler, D.O, M.P.H., is chief quality officer for the OU Physicians clinical practice and a professor in the OU Colleges of Medicine and Public Health. He also is a national expert on surgical site infections and evidence-based methods of their prevention. “Surgical site infections are still common, and their severity will vary based on the location of the infection and the complexity of the operation,” Bratzler said. “For example, if patients get an infection while undergoing cardiac bypass surgery or having a hip replacement, the results can be devastating. Surgical site infections dramatically increase the cost of care, cause disability for patients and may require several operations to address the problem, in addition to treatment with antibiotics.” Bratzler was a lead author for the study, which was published in JAMA Surgery and officially adopted as a CDC guideline. As part of their work, the authors queried community hospitals and surgeons about what questions they wanted answered concerning surgical site infections. The group then reviewed thousands of articles on randomized controlled trials concerning prevention of surgical infection. Following are some of the major recommendations: • For any type of surgery, outpatient or inpatient, the new recommendation is to stop giving all antibiotics once the incision is closed. Doctors have often continued to give antibiotics to the patient after they close the wound. However, studies consistently show no benefit to continuing to give antibiotics. In addition, continuing antibiotics leads to a 60 percent increased risk that, if the patient is infected, it would be from an organism that is resistant to antibiotics. “Most surgical infections start in the operating room when the wound is open – that’s when the wound can become contaminated with

Dale Bratzler, D.O, M.P.H. bacteria,” Bratzler said. “When the surgeon closes the wound, the bacteria stays in the closed space, which doesn’t have much blood flow because the blood vessels have been cauterized. Giving additional antibiotics after the surgery is over isn’t going to make a difference and can be harmful.” • To reduce the chance of a mother getting an infection during a Caesarean section, doctors should give antibiotics before the incision is made. Previously, doctors would wait until the baby’s umbilical cord was clamped before giving the mother antibiotics. However, studies consistently show that antibiotics provide better protection when given before the incision, and doing so does not adversely affect the baby. • Keeping patients warm in the operating room reduces the risk of surgical infections. • Supplemental oxygen during major operations – both in the operating room and after surgery – has been shown to reduce infections. • Controlling a patient’s blood sugar after surgery reduces the risk of infection. High blood sugars impair the body’s ability to fight off infection. • Use an alcohol-based skin antiseptic to clean the skin before an incision is made. Alcohol rapidly kills bacteria. “The most important thing to remember is that half of the surgical site infections that occur are potentially preventable if we implement these evidence-based guidelines,” Bratzler said. “Our recommendations are based on what the evidence shows will reduce the risk of developing a surgical infection.” 11

A Patient’s Journey with Alpha Gal Allergy Oklahoma Allergy & Asthma patient, Stan Basler, has had to learn the hard way of living with a life-threatening allergy. An allergy caused by the bite of the Lone Star tick, Galactose-alpha-1,3-galactose, or Alpha-Gal for short, has totally changed his life, from the foods he can eat and medications he has to take. Until recent years, a new type of food allergy has been discovered called Alpha Gal. This allergy is to galactose-alpha, 1,3-galactose, a carbohydrate found on mammalian meat. People become sensitized to this carbohydrate after being bitten by the Lone Star Tick. Unlike other types of food allergies which typically occur more immediately, alpha gal reactions are typically delayed by 4 to 8 hours which can awaken the person in the middle of the night. People with alpha gal should avoid eating beef, lamb, pork and venison. His initial diagnosis was July 2014. “I had a hive attack at church camp in May of 2014,” said Basler. “The second hive attack hit in July, I didn’t know what to do so I took some Benadryl, then all of the sudden my hands swelled and my tongue got big and then I collapsed.” He crawled to the bedroom to alert his wife and collapsed again. After being taken by ambulance to the emergency room, the ER Physician told him after taking his medical history that he was having an allergic reaction. Basler, at first, thought he had a reaction to some kind of chemical to the flooring he had sat on in shorts at the church camp cabin. “I was very fortunate to get a quick appointment with Dr. Laura Chong, my OAAC allergist,” Basler said. “She listened to my story and performed some blood

Stan Basler

testing. Then we knew it was alpha-gal. I was also very fortunate to find out because I ate a lot of mammalian meat and did not have a reaction previously.” Basler and his wife live next to a greenbelt area and, at the time, he was diagnosed had eight to ten tick bites. He has learned to serve as his own advocate due to so many not understanding the alpha-gal allergy. “I’ve had to educate people within the medical community as well as to restaurant staff about the allergy,” he said. “When I am in a restaurant, I have to ask, ‘do you cook your chicken on the same grill as beef or pork?’ I have to tell them – when you are scooping up the food, don’t use the same tongs because of cross-contamination. I’ve been pleasantly surprised on how cooperative and sensitive restaurant food service people have become.” He also noted that many medicines have gelatin in them which is a substance derived from the processing of animal collagen. Changing his eating habits has been hard for this selfproclaimed food lover of hamburgers, barbecue and pepperoni. “It’s like cheating on a diet, but if you want to live, this is what you have to do,” said Basler.

The Culprit the Lone Star Tick 12

“Dr. Chong is a very conscientious and responsible doctor,” he said. “She is very proactive.” Basler sees Dr. Chong every six months to monitor his alpha gal status.

National Breastfeeding Month August is National Breastfeeding Month. This campaign, funded by the U.S. Department of Health and Human Services, seeks to empower women to commit to breastfeeding by increasing knowledge and providing supportive resources to extend the period in which moms express breastmilk for their babies. Breastmilk offers many health benefits, and the longer babies breastfeed, the greater the return on those benefits. Breastfeeding may reduce an infant’s risk of developing ear infections, asthma and respiratory illnesses. Breastfed infants also may be less likely to develop lifelong conditions such as childhood obesity, diabetes, cancer and more. Health benefits extend to mothers as well, as breastfeeding may provide some protection against ovarian and breast cancers, lower risk of rheumatoid arthritis, heart disease, diabetes, and promote the loss of unwanted pregnancy weight. The theme of this year’s observance is “Support Breastfeeding —Together,” and our patients will have opportunities to give thank-you cards to specific staff specific staff members who have helped them. “Thank You for Supporting Breastfeeding” cards are a way to celebrate how we all work together to achieve breastfeeding goals. As an enterprise, OU Medicine supports breastfeeding mothers as a patient population as well as part of our employee base. In fact, OU Physicians and OU Medical System are certified by the Oklahoma State Department of Health as Breastfeeding Friendly Worksites. Across the Health Sciences Center campus, 30 lactation rooms are available to provide privacy for mothers who want to express milk. For locations available on campus, visit here. https://apps.hr.ou.edu/dms/documents/files/ Rooms_Available_for_Nursing_Mothers_at_HSC/ Staff_Lactation_Rooms_OUHSC_11-2016.pdf Throughout August, Fox 25 will showcase an OU Physicians outpatient lactation consultant in a cooking segment. Tune in weekly for “Cooking and Breastfeeding” for tips and great recipes. Other supportive resources: • The Oklahoma Breastfeeding Hotline, 877-2716455 (MILK), is a toll-free number where nursing mothers can find answers to questions at any hour, day or night. Supported by our own internationally board-certified lactation consultants, this resource is provided at no cost, in both Spanish and English.

• On-site breastfeeding classes are held monthly at The Children’s Hospital, 4th floor, 4NP527 Family Education room. For more information or to enroll, call 405-271-5000, or visit the Breastfeeding Basic Classes website. https://epay.ouhsc.edu/C22824_ ustores/web/store_cat.jsp?STOREID=38&CATID =19&SINGLESTORE=true • The OU Physicians Breastfeeding clinic is available Monday through Friday, to provide help for breastfeeding mothers Services are covered by most insurance plans. Call 405-271-9494 for an appointment.

It’s Coming: Fall Music Festival

Every Wednesday, September through October, enjoy live music and great food, both with wide varieties in style and taste. Food vendors located at Phillips and Stanton L. Young Blvd. Food trucks from week to week may include: • The Hall’s Pizza Kitchen • Klemm’s Smoke Haus • Let’s Do Greek • Midway Deli • Mutt’s Amazing Hot Dogs • Parking Lot Party • Phill Me Up Cheesesteaks • Pitchfork Kitchen and Bakery • Roxy’s Ice Cream Social • Saucee Sicilian • Smokin’ Okies • Snow S’more • Taste of Soul Egg Roll • Twist Gourmet Pretzels • Sacred Valley Park, (south of Professional Office Building, north of Service Center Building) 11 a.m. and 1 p.m., Wednesdays, beginning September 6 through October 25 13

Oklahoma Health Center Campus *Member Organizations Oklahoma Health Center Foundation

1. American Red Cross of Central Oklahoma 2. Dean McGee Eye Institute* 3. Department of Veterans Affairs Medical Center 4. Easter Seals Oklahoma* 5. Office of the Chief Medical Examiner 6. Oklahoma Allergy and Asthma Clinic* 7. Oklahoma Blood Institute* 8. Children’s Hospital Foundation* 9. Oklahoma Medical Research Foundation* 9a. OMRF Research Tower* 9b. OMRF Bell Building* 9c. OMRF – Acree-Woodworth Building* 9d. OMRF – Massman Building* 10. Oklahoma School of Science and Mathematics* 11. Oklahoma Department of Health* 12. General Electric Global Research* 13. Department of Human Services 14. OU Medical Center* A. Professional Office Building B. OU Medical Center C. The Children’s Hospital D. Oklahoma Transplant Center E. OU Medical Center Surgical Center 15. OU University Research Park 655 Conference Center Pall Forte Oklahoma Business Roundtable Oklahoma State Regents OneNet OTRC OU Medical Center Financial Services OU Medical Center Marketing Presbyterian Health Foundation* Potts Family Foundation Pure Protein SIWA ViewSolid, Inc. 755 DNA Solutions COARE Biotech Haus Spaus Department of Veterans Affairs Medical Center URP Management Office MedEncentive Moleculera NewSpin360 Nova Venture Services, LLC OCAST*

OptumRX Oklahoma Tobacco Research Center OUHSC Center for Intelligence and National Security* Potawatomi Federal Solutions Purmabiologics Sigma Blood Systems Sylvia Bottomley 800 Biolytx Pharmaceuticals Corp. Charlesson Comp. Risk Management Crisalis Cytovance Biologics EyeCRO Inoveon Oklahoma Health Center Foundation* OU Health Sciences Center* Transtimulation Research, Inc. Zanek 825 Camilles Sidewalk Cafe Richey’s Grill 840 ARL Bio Pharma* Cytovance Biologics DNA Solutions* Gear Up i2E, Inc. LabCorp Office of Educational Quality and Accountability Oklahoma State Regents for Higher Education OU Physicians - Reproductive Medicine* OUHSC Financial Services* OUHSC Payroll* Selexys Pharmaceuticals 865 Accele Biopharma ARL Bio Pharma* Drik LLC Michael F. Price College of Business Miles Associates OUHSC Office of the Vice President for Administration and Finance* OUHSC Facilities Management* OUHSC Office of the Fire Marshal* OUHSC Grants and Contracts* OUHSC Office of Research Administration* OUHSC Vice President for Research* OUHSC Vivarium* University Health Club 885 Cytovance Biologics

16. University of Oklahoma Health Sciences Center* A. Allied Health Practice Center B. Basic Sciences Education Building C. Campus Police Station D. College of Allied Health E. College of Dentistry F. Biomedical Sciences Building G. Fran and Earl Ziegler College of Nursing H. Henry D. & Ida Mosier College of Pharmacy I. College of Public Health J. David L. Boren Student Union K. Don E. Hogg Greenhouse L. G. Rainey William Pavilion M. Harold Hamm Diabetes Center N. O’Donoghue Research Building - OU Medical Center Senior Health Clinic O. Stephenson Cancer Center P. Child Study Center Q. OU Physicians Building* R. OU Physicians Dermatology* S. OU Physicians Family Medicine Center* T. Robert M. Bird Library and Graduate College U. OUHSC Technology Center V. Service Center Building W. Stanton L. Young Biomedical Research Center X. Steam and Chilled Water Plant Y. University Health Club Z. University Village AA. OUHSC Faculty House BB. OUHSC (Formerly Oklahoma City Clinic) CC. OU Children’s Physicians 16. Oklahoma State Department of Mental Health and Substance Abuse Services* (located off campus) 17. University Hospitals Authority and Trust* 18. Ronald McDonald House Charities of Oklahoma City* 19. Ronald McDonald Family Room (in The Children’s Hospital)* 20. Ronald McDonald House II (in Garrison Tower)* 21. Andrews Academic Tower (UHAT)* 22. Embassy Suites Downtown/Medical Center* 23. OK Kids Korral 24. Oklahoma Employees Credit Union* (located off campus)

RSVP https://www.eventbrite.com/e/mind-meld-an-innovation-district-networkingevent-tickets-36324636967

ARL Bio Pharma, Inc.

Children’s Hospital Foundation

Dean McGee Eye Institute

DNA Solutions, Inc.

Easter Seals Oklahoma

Oklahoma Allergy & Asthma Clinic

Oklahoma Blood Institute

Oklahoma Center for the Advancement of Science and Technology

Oklahoma Health Center Foundation

Oklahoma Department of Mental Health & Substance Abuse Services

Oklahoma State Department of Health

Oklahoma Medical Research Foundation

Oklahoma School of Science & Mathematics

OU Medical Center

OU Physicians

Presbyterian Health Foundation

Ronald McDonald House Charities® of Oklahoma City

University Hospitals Authority and Trust

University of Oklahoma Health Sciences Center: College of Allied Health • College of Dentistry College of Medicine • College of Nursing College of Pharmacy • College of Public Health Graduate College • Stephenson Cancer Center Harold Hamm Diabetes Center

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Member Organizations

Associate Members Oklahoma Employees Credit Union

Embassy Suites

Member

Tom Kupiec, Ph.D., President and CEO 840 Research Parkway Suite 546 Oklahoma City, OK 73104 Phone: (405)271 1144 Website: www.arlok.com ARL Bio Pharma is a contract laboratory that provides analytical and microbiological testing services for the pharmaceutical industry. Our laboratory works with pharmaceutical companies, compounding and hospital pharmacies, drug manufacturers, academic institutions, and research scientists bringing excellence to pharmaceutical sciences. ARL recognizes the importance of providing quality testing services. With over 100,000 formulations tested, we assist our clients in providing quality drug products to their patients. Our services include: full analytical and research and development support, stability and compatibility studies, micro-

biology testing, dissolution testing, microbial identification, bioequivalence studies, and pre-clinical and clinical support. ARL also assists local and government agencies and regulatory bodies with forensic drug investigations including: drug diversion testing, chemical and biological analysis, complaint sample testing, litigation support, product contamination and patent infringement. Contact ARL for more information on analytical, microbiological analysis and forensic drug investigation services at 800-393-1595.

Member

Kathy McCracken, Executive Director 6501 Broadway Extension, Suite 190 Oklahoma City, OK 73116 Phone: (405) 271-2260 Toll Free: 888-229-KIDS Tax ID: #73-1200262 Website: www.chfKids.com Children’s Hospital Foundation is the only nonprofit organization in Oklahoma whose sole focus is the advancement of pediatric research and education while supporting specialized clinical care for Oklahoma’s children. Since its inception in 1983, Children’s Hospital Foundation has raised and leveraged matching funds to create more than $110 million for pediatric research, quality specialized clinical care and education programs. Many of these endeavors include collaborative projects with the University of Oklahoma College of Medicine and Children’s Hospital at OU Medical Center in Oklahoma City.

All funds raised in Oklahoma stay in Oklahoma so that families don’t have to leave the state to receive specialized care. CHF supports pediatric specialists who treat more than 225,000 patient visits every year including children in all 77 counties and no child is ever turned away, regardless of ability to pay. CHF is currently recruiting endowed chairs and has naming opportunities available. For more information, contact Children’s Hospital Foundation toll free 888-229-KIDS (5437) or (405) 271-2260.

Current program and research focus areas include: • Infectious disease • Arthritis • Education • At-risk newborns • Diabetes-Obesity • Digestive health • Cancer • Genetics • Community pediatrics • Surgery & Emergency • Autism-ADHD-Down Syndrome • Lung, kidney and heart disease • Adolescent medicine • Eating disorders • Behavioral medicine • Child abuse and neglect Funding for their programs is made possible through the efforts of a dedicated volunteer board, thousands of community volunteers and donors. Through endowments and direct support, they are able to recruit and retain nationally and internationally recognized pediatric physician-scientists to direct research, treat patients and train medical students.

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Gregory L. Skuta, M.D., President and CEO 608 Stanton L. Young Blvd. Oklahoma City, OK 73104-5065 Phone: (405) 271-6060 Website: www.dmei.org Benchmarks of Dean McGee Eye Institute Excellence The Dean McGee Eye Institute is one of the largest and most respected eye institutes in the United States, providing more than 176,000 patient visits per year from all 77 Oklahoma counties and the surrounding region, and serving more than 8,100 surgical patients annually in its state-ofthe-art ambulatory surgery center. Twenty of the Eye Institute’s ophthalmologists are listed among the Best Doctors in America. The University of Oklahoma (OU) College of Medicine’s Department of Ophthalmology, which is housed in the Dean McGee Eye Institute, ranks among the country’s top departments in National Institutes of Health funding and is 12th in the nation in cumulative funding from Research to Prevent Blindness. The Dean McGee Eye Institute’s residency program (in affiliation with the OU College of Medicine) attracts top medical students from throughout the nation. Resident surgical education has consistently ranked above the 90th percentile nationally. Since 2000, the first-time pass rates on the American Board of Ophthalmology’s written and oral examinations are 100% and 98% respectively with an average score on the written examination at the 80th percentile. The Eye Institute’s Director of Vision Research is a Past President of the International Society for Eye Research, Past Vice President of the Association for Research in Vision and Ophthalmology (ARVO) and a recipient of ARVO’s prestigious Proctor

Medal; two members of the faculty are recent or current directors of the American Board of Ophthalmology; three serve or have recently served on the Board of Trustees of the American Academy of Ophthalmology (AAO); one will be President-Elect of the AAO in 2016; another has recently served as Vice Chair of the Residency Review Committee in Ophthalmology for the Accreditation Council for Graduate Medical Education; and one is the Immediate Past President of the AAO and a Past President of the American Glaucoma Society.

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Thomas C. Kupiec, Ph.D., CEO and President 840 Research Parkway, Ste. 551, Oklahoma City, Oklahoma 73104 Toll Free: (866) 362-9778 Phone: (405) 271-6033 Website: www.dnasolutionsusa.com

As a world leader in genetic and human remains testing, our laboratory partners with federal, state, and city government agencies to assist in the processing of forensic casework including the United States Department of Agriculture, Federal Aviation Administration, police agencies, District Attorneys, Public Defenders, and Medical Examiners.

DNA Solutions is a genetic testing laboratory that reveals answers contained within the strands of DNA. Trusted for over 17 years, our dedicated team of scientists utilizes the most advanced technologies to deliver superior, cost effective results for many types of genetic testing including humans, animals, and microbial identification.

DNA Solutions also works with academic and private researchers to develop novel genetic applications and technologies including single nucleotide polymorphisms (SNPs), allele determination, and marker development.

Our laboratory is one of a select few private labs in the United States that has the combination of FBI Quality Assurance Standards, American Association of Blood Banks, and ISO/ IEC 17025 accreditations including our accreditation in Mitochondrial DNA sequencing.

Contact DNA Solutions today if you require DNA Testing at (405) 271-6033 or www.dnasolutionsusa.com.

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Paula K. Porter, President & CEO 701 NE 13th Street Oklahoma City, OK 73104 Phone: (405)239-2525 Website: www.eastersealsok.org More than 56 million Americans have a disability, which accounts for approximately 19 percent of the population. Easter Seals Oklahoma is the leading nonprofit provider of services for individuals with disabilities and is trying to bridge the gap for the increasing number of Oklahomans needing services.

or improve their ability to remain independent. The program provides various activities to stimulate minds, promote social interaction and keep everyone moving. Our early learning and inclusion academy includes an onsite learning program for children with disabilities as well as typical children, and a peer integration program to increase early intervention. Consultation services are available for parents and teachers that need additional support and training on developmental disabilities. Easter Seals Oklahoma also provides direct financial assistance for children needing therapy, as well as a variety of rehabilitative equipment that is necessary for a childâ&#x20AC;&#x2122;s development. Medical rehabilitation is available onsite for behavioral, occupational and speech therapies. It is our mission at Easter Seals Oklahoma to enhance the quality of life for children and adults with disabilities so they may live with equality, dignity and independence. Thanks to the support of the community, we are able to fulfill our mission.

For more than 90 years, we have been offering help and hope to children and adults with disabilities and to the families who love them. Through therapy, training, education and support services, Easter Seals Oklahoma creates life-changing solutions so that people with disabilities can live, learn, work and play. Our adult day health center provides special care for adults who are unable to care for themselves for extended periods of time and enables them to maintain

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Serving Oklahoma and the southwest since 1925, the Oklahoma Allergy & Asthma Clinic is one of the oldest and largest medical practices in the United States dedicated solely to the treatment of allergy, asthma and immunology. The Oklahoma Allergy & Asthma Clinic has eight physicians on its medical staff; board certified by the American Board of Allergy & Immunology and are on the teaching faculty at the University of Oklahoma College of Medicine. The Oklahoma Allergy & Asthma Clinic is one of only a few allergy groups in the United States with a full-time Nurse Practitioner who holds a Doctorate and is a pulmonary disease management coordinator consulting with individual patients about breathing techniques and asthma education. Also on staff is are two full-time, registered, licensed nurse practitioners. Almost one-fourth of The Oklahoma Allergy & Asthma Clinicâ&#x20AC;&#x2122;s patients are referred from outside Oklahoma City and travel many miles for the sophisticated, high-level al-

Scott B. Dennis, MHA 750 N. E. 13th Street Oklahoma City, OK 73104-5010 Phone: (405) 235-0040 Website: www.oklahomaallergy.com Facebook oklahomaallergyandasthmaclinic Twitter @okallergyasthma lergy and asthma care and to participate in the numerous research studies. The Oklahoma Allergy & Asthma Clinic has a Burkard pollen and mold collection instrument on the roof of its main location and provides the daily counts to the media and the counts are also posted on the website and on social media. The Oklahoma Allergy & Asthma Clinic has its central clinic location on the Oklahoma Health Center campus. Four full-service satellite clinics are located in Edmond, Norman, Midwest City and Northwest Oklahoma City, adjacent to Mercy Hospital. A new Norman practice building opened in December 2016. How is an allergist different than a regular physician? An allergist is a doctor who is an expert in the diagnosis and treatment of allergic diseases and conditions. Those conditions include asthma and frequent coughing; hay fever; sinus infections; eye allergies; reactions to food, insect stings and drugs; and immune system problems that might cause frequent infections. You should see an allergist if you have any of these conditions. More than 50 million people in the United States have these allergic diseases. Although symptoms may not always be severe, allergies and asthma are serious and should be treated that way. Many people with these diseases simply donâ&#x20AC;&#x2122;t realize how much better they can feel with proper treatment. An allergist is trained to find the source of symptoms, treat it and help patients feel healthy. After earning a medical degree, the doctor must complete a three-year residencytraining program in either internal medicine or pediatrics. Then, an allergist completes two or three more years of study in the field of asthma, allergy and immunology.

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our ability to recruit marrow registrants from ethnically and age-diverse populations.

John Armitage, M.D., President, CEO 1001 N. Lincoln Blvd. Oklahoma City, OK 73104 Phone: (405) 278-3100 Website: www.obi.org Oklahoma Blood Institute (OBI) is the ninth largest, nonprofit blood center in America. Every drop of blood needed by patients in more than 140 medical facilities in Oklahoma is provided by donors with OBI. This includes exclusive service for every hospital in the metro-OKC area. An average of 700 donors a day is required to meet these needs. Volunteer blood donors give more than a 287,000 units of blood annually to provide a safe and adequate blood supply. Blood donors with Oklahoma Blood Institute know they are, literally, saving the lives of their friends, family and coworkers, some who may have no idea they will need blood in an urgent situation. One blood donation can save as many as three peoples’ lives. OBI is responsible for recruiting blood donors, collecting, processing and testing blood components and transporting it to hospitals across our state. Random inspections by the Food & Drug Administration (FDA) confirm the quality of our operations at every donation site. OBI’s perfect record through 36 straight inspections validates our quality exceeding regulatory requirements. OBI employs 642 Oklahomans and works with 1,200 volunteers and 2,600 blood drive coordinators. Its donor centers are located in Ada, Ardmore, Edmond, Enid, Lawton, Norman, central Oklahoma City (Oklahoma Health Center), north Oklahoma City and Tulsa. Numerous mobile blood drives are conducted in conjunction with businesses, schools and civic groups each week across the state. Oklahoma Blood Institute is the state’s only affiliate of Be The Match®, the national marrow donor program. For more than 12,000 Americans each year, a marrow or stem cell transplant is the only hope for a cure of a life-threatening blood cancer or other blood disorder. For the past three years, OBI has ranked in the top performance tier, due to

Oklahoma’s first and only umbilical cord blood bank is in the final phases of FDA accreditation at OBI. It is one of only 24 accredited centers worldwide. Expectant mothers of underserved ethnic descent families now have an opportunity to donate cord blood. There is no charge to the parents, and the donation process is simple and painless. During a blessed time in their own lives, this cord blood center enables Oklahoma families to potentially bring life-saving joy to someone else’s. OBI is a vital link in cell therapy, procuring healthy stem cells for transplants from adult marrow and umbilical cord donations. The future holds great promise as we expand research and treatments partnerships within the healthcare biosciences industry. Cell therapies and regenerative medicine applications are predicted to revolutionize care for the most life-threatening diseases. We are uniquely positioned as a ready-made ‘cell bank’ with hundreds of thousands of combinations of genetic characteristics among our blood donors. These giving people may be offered the opportunity to further make a difference in the lives of others as part of medical research. Oklahoma Blood Institute can accelerate this revolutionary research cost effectively, so that today’s vision more rapidly becomes the reality of life-enhancing, routine medical treatments.

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Michael Carolina, CEO 755 Research Parkway, Suite 110 Oklahoma City, OK 73104-3612 Local: (405)319-8400 Toll Free: 866-265-2215 In Tulsa: 618 East Third Street, Suite 5 Tulsa, OK 74120 918-576-7650 Website: www.ocast.ok.gov Facebook: www.facebook.com/ocast.ok.gov Twitter: www.twitter.com/ocast The Oklahoma Center for the Advancement of Science and Technology (OCAST) was established in 1987 as the state’s agency for technology-based economic development. OCAST’s mandate is to “expand and diversify Oklahoma’s economy and provide new and higher quality jobs for Oklahomans” by encouraging “. . . the development of new products, new processes and

whole new industries in Oklahoma.” (O.S. 74, Sections 5060.1a and 5060.2A) MISSION To foster innovation in existing and developing businesses • by supporting basic and applied research • by facilitating technology transfer between research laboratories and businesses • by providing seed capital for innovative firms in the development of new products or services • by helping Oklahoma’s small and medium-sized manufacturing firms become more competitive through increased productivity and modernization (O.S. 74, Section 5060.3) VISION OCAST funds cutting-edge science and technology through processes that are recognized nationally and internationally for demonstrating excellence, objectivity and economic impact. OCAST’s vision is continued growth and vitality of its basic premise of facilitating collaborations between state government, universities, start-up companies and established large-scale firms to develop an entrepreneurial environment which supports technologybased economic development. OCAST’s strategy includes technologies such as biosciences, information technology, sensors and electronics, advanced materials, energy and alternative fuel sources. Achieving this vision will result in continued growth of advanced technology companies in the state thereby increasing Oklahoma’s global competitiveness, per capita income and quality of life.

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Terri White ODMHSAS Commissioner 2000 N. Classen Blvd, Ste E600 Oklahoma City, OK 73106 Phone: (405) 522-3908 Website: www.odmhsas.org

The Oklahoma Department of Mental Health and Substance Abuse Services is responsible for providing services to Oklahomans who are affected by mental illness and substance abuse. In fiscal year 2008, the department provided services to 64,465 individuals – an increase of nearly 3,600 individuals over the previous year. The demand for public mental health services exceeds the capacity of the current treatment system. This has always been the case, but has been exacerbated in recent years due to a growing public awareness of mental illness and of the existence of effective treatment; rising healthcare costs; and the state’s growing substance abuse problem, particularly the brain-damaging use of methamphetamine and resultant psychotic behavior. Through the use of proven practices and expansion of community based services, the department will increase the effectiveness of services and continue to improve the efficiency of the delivery system. The department’s goal is to ensure access to appropriate care for all Oklahomans and the recovery of all served. The ODMHSAS was established through the Mental Health Law of 1953, although publicly supported services to Oklahomans with mental illness date back to early statehood. Until the mid-1960s, the primary means to treat mental illness was institutionalization in large state hospitals. On an average day in 1960, nearly 6,400 Oklahomans were in the state’s mental hospitals.

In the mid-1970s, the concept of “deinstitutionalization” prompted states to increase efforts to utilize outpatient services through Community Mental Health Centers. This approach has proven to be an effective means of recovery and a less costly method to provide services as compared to long-term inpatient care in a hospital setting. Today, over 60,000 individuals receive services from the department each year. Of those, only about 5 percent require hospital care. The vast majority take part in mental health and substance abuse outpatient programs, targeted community based services, prevention efforts and educational initiatives. In fact, Oklahoma has become a national leader in several areas of community based services including the implementation of programs for assertive community treatment, alternative criminal justice initiatives such as drug and mental health courts, and comprehensive services for children and families. In many ways, Oklahoma already is “ahead of the curve” in terms of treatment success for people with mental illness or substance abuse problems. With a focus on community-based and proven practices, and emphasis on treatment across the lifespan, from children to the elderly, more Oklahomans with mental illness and substance abuse problems are being served than ever before.

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Terry Taylor, President 800 N. Research Parkway, Suite 400 Oklahoma City, OK 73103 Phone: (405) 271-2200 Website: www.oklahomahealthcenter.com The mission of the Foundation is to promote innovations in healthcare and science, and to serve as a connector between our member organizations, in order to raise awareness of the Oklahoma Health Center’s profile among business and governmental entities as a key driver of economic development. The Oklahoma Health Center (OHC) is unique, unlike any other medical center in the United States or even the world. With an annual economic impact of almost $3 billion in the greater Oklahoma City area, the OHC represents the second largest concentration of employees and students in Oklahoma — more than 18,000 —larger than a number of Oklahoma communities. Chartered in 1965, the Oklahoma Health Center Foundation, Inc. (OHCF) was established to assist the Oklahoma Health Center, and its 21 member entities, in matters of mutual physical, administrative and planning concerns. This assistance helps drive the OHC’s potential in attracting and developing biomedical and biotechnical industries in Oklahoma. From cutting-edge biotechnology companies to government, medical education, patient care and community support institutions, OHCF serves as the facilitator to 21 world-renowned organizations. OHCF works closely with many aspects of the campus and its organizations, serving as a liaison between Federal, State, County and City governments by representing the various interests of the campus.

OHCF’s Board recently voted to assume management of the emerging OKC Innovation District which encompasses the Health Center across I-235 to Automobile Alley. OHCF, in the spirit of fostering collaboration, OHCF is hosting symposiums and quarterly Mind-Meld events. OHCF is a founding member of the 10th Street Medical Business Corridor, a vital and stabilizing anchor to north downtown, which links the OHC campus to other medical facilities in the area, along 10th street. OHCF is responsible for the implementation of the campus Master Plan, which seeks to establish the Treasures For Tomorrow program began in 2002, and almost $3 million was raised. Projects included public art sculptures at Dean McGee Eye Institute and The Children’s Hospital, and Founders Plaza at Stiles Park featuring the Beacon of Hope. In 2016, the focus was changed to donate monies raised to health-related research projects. Treasures For Tomorrow, $50,000 was awarded to OUHSC and the Harold Hamm Diabetes Center to further the research on this existing project focusing on diabetes. OHCF is involved in the plans for a modern and comprehensive way-finding signage project. Since 2000, more than $534 million in construction costs have been completed at the campus. OHCF continues to serve as a facilitator between developing agencies and their surrounding agencies, ensuring the successful and orderly growth of the campus. OHCF continues to serve the campus interests as a key stakeholder through meetings with the City of Oklahoma City in discussing the proposed MAPS 3 streetcar development and its potential service to the OHC. OHCF continues to represent the interests of the OHC in the successful, revitalization development of downtown Oklahoma City by closely working with the City of Oklahoma City, the Greater OKC Chamber of Commerce and Downtown OKC, Inc. 27

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Terry Cline, Ph.D. Commissioner 1000 N.E. 10th Oklahoma City, OK 73117 Phone: (405)271-4200 Website: www.health.ok.gov A Day in the Life of Public Health… From the time you get up in the morning till you go to bed at night, public health is involved in your life: • When you got up this morning, you made food choices for breakfast. We provide you messages on healthy food choices. • You have a yearning for that cigarette you are trying to give up. We work with the Oklahoma Tobacco Helpline to help you quit smoking. • Hopefully, you brushed your teeth. We work with communities to fluoridate water supplies. • You got in the car and buckled in your children, put the baby in the car seat, and buckled your own seatbelt. We encourage seat belt use and provide car seats to those who need them. • You dropped the kids off at school. All should have their mandated immunizations to protect them from childhood diseases. We provide immunizations. • You go to work where most of your colleagues seem to be sick. We investigate disease outbreaks. • You go to lunch at a local restaurant. We inspect food service facilities. • You decide not to go back to work – since everyone’s sick anyway – so you think you’ll get that tattoo you’ve been dreaming about. We license tattoo artists. • You decide to visit your grandmother to show off your new tattoo. She’s at a local nursing facility. We license nursing homes. • You pick the kids up from the after-school program. It’s one that works with the health department to 28

provide lots of physical activity and healthy snacks. • You stop off at the grocery store where you see a friend selecting fresh fruits and produce. You know she’s on WIC, the special nutrition program for women, infants and children. We administer the program. • You start to prepare dinner. You wash your fruits and vegetables to help prevent contamination from E. coli bacteria. The Public Health Laboratory analyzes food specimens during foodborne illness outbreaks. • Your sister calls and says she has enrolled in the Children First program. This is a special nurse visitation program provided by county health departments to visit first-time mothers in their home and teach them about caring for their new baby. • After dinner you go for a walk and let the kids ride their bikes. Public health partners with communities to encourage safe sidewalks and bike trails to promote physical activity. • While outside, you make sure everyone has used insect repellent containing DEET to prevent mosquito bites and tick bites. We investigate cases of West Nile virus caused by mosquito bites, and Rocky Mountain spotted fever, caused by tick bites. • You put the baby to bed in a crib that meets current federal safety standards and is free of bumper pads so the baby cannot suffocate. You place the baby on its back, the safest position. We provide education on child safety. • On the 10 o’clock television news, you learn that HIV continues to be of concern in Oklahoma. Public health provides testing for HIV. • Overnight, a tornado hits your community. When you turn on the radio the next morning, you hear messages that your local health department will be providing tetanus shots for those involved in the cleanup. So indeed, public health is at work every day to keep Oklahomans healthy!

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Stephen M. Prescott, M. D., President 825 N.E. 13th Street Oklahoma City, OK 73104 Phone: (405)271-7400 Website: www.omrf.org JOBS at OMRF -- https://jobs.omrf.org/applicants/jsp/ shared/frameset/Frameset.jsp?time=1380829938244 What if there was a place solely focused on research? A place where collaboration could thrive and ideas could grow? Where the stage was set for life-changing discoveries? There is.

It’s the Oklahoma Medical Research Foundation. • OMRF scientists hold 700 US and international patents and have developed two FDA-approved drugs. • The Scientist magazine named OMRF among the “Best Places to Work” for postdocs and in academia in 2011, 2012 and 2013. • For our work on rheumatoid arthritis and lupus, the National Institutes of Health has designated OMRF as one of only nine Autoimmunity Centers of Excellence in the US. • Our internationally recognized cardiovascular biologists are studying how blood-vessel formation impacts heart disease and breast and colon cancer. • Researchers at OMRF have identified more than 25 genes associated with lupus and five linked to Sjögren’s syndrome.

• Physicians in OMRF’s Multiple Sclerosis Center of Excellence offer the region’s most comprehensive center for researching and treating MS. • OMRF is seeking novel methods of preventing age-related macular degeneration, hearing loss, osteoarthritis and diabetes. • For 12 consecutive years, OMRF has earned a four-star rating—the highest possible score—from Charity Navigator, America’s largest independent charity evaluator. • With 18 vertical wind turbines that generate 85,000 kilowatt hours of energy each year, OMRF’s research tower is home to the world’s largest wind farm. • Our new biorepository holds more than 1 million patient samples in a massive freezer that maintains a constant temperature of -112 degrees Fahrenheit. • Scientists at OMRF led the largest genetic experiment ever in the field of lupus research, working with 50 scientists in 6 countries to study biological samples gathered from 15,000 patients. • OMRF has discovered an experimental medication to treat a deadly form of brain cancer. The investigational new drug is currently in clinical trials. OMRF. Discoveries that make a difference.

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Oklahoma School of Science and Mathematics Frank Wang, Ph.D., President The Oklahoma School of Science and Mathematics 1141 North Lincoln Boulevard Oklahoma City, Oklahoma 73104 Phone: (405) 521.6436 Website: www.ossm.edu Only one of a handful of high schools of its kind in the nation, the Oklahoma School of Science and Mathematics is a unique learning institution for Oklahoma students. OSSM is Oklahoma’s public residential high school for juniors and seniors with exceptional interest and abilities in mathematics and science. OSSM operates its two-year residential program in Oklahoma City, Regional Center programs around the state and also serves all Oklahoma schools and students through math contests, research, teacher training and outreach activities. OSSM was created by the Oklahoma Legislature in 1983 and is funded by the state, with additional private partnership garnered by the OSSM Foundation. The school is governed by a Board of Trustees appointed by legislative leaders and the Governor. Located on a 32-acre site near the state capitol and adjacent to the teaching and scientific research resources of the Oklahoma Health Sciences Center, OSSM is committed to building a strong academic foundation for each student. The school’s residency program is designed to encourage an atmosphere of informal interaction among peers and foster each student’s highest potential. The availability of laboratories along with evening and weekend programs of interest challenge students and stimulate studies. Since classes began in 1990, students have matriculated from all of Oklahoma’s 77 counties to undertake OSSM’s advanced curriculum taught by a world class, largely Ph.D. faculty, leaping forward in their academic progress. While in residence at OSSM for their junior and senior years, students receive five and one-half days of academic instruction every week in college-level courses 30

and participate in physical education and Fine Arts programs. Most science classes feature a two-or-threehour weekly laboratory experience, and many seniors participate in mentorship programs with researchers and other professionals in areas of personal interest. Students must also receive satisfactory participation reports in both campus and community service of which a total of 120 hours are required for graduation (see more at www.ossm.edu/academics). All OSSM graduates go on to pursue higher education with many earning valuable scholarships and, depending on their receiving school, many begin college with substantial credit hours already completed. OSSM graduates are continuing to leave indelible marks on Oklahoma. Of the more than 1,500 OSSM graduates thus far, more than a third have pursued engineering and roughly another third are in medicine or bioscience. Based on alumni reports, we estimate more than half of OSSM grads who have completed their higher education have also earned graduate degrees, and a substantial number have served or are serving in the U.S. armed forces. Some 85% of OSSM alumni are staying in careers in science, math, engineering and technology. More than half are now working or living in Oklahoma and a number have also begun their own businesses. GE Global Research cited OSSM as one of ten critical site selection factors in their decision to build a new research facility in Oklahoma City, and a recent independent analysis found OSSM and its graduates already stimulating more than $40 million each year in economic activity in Oklahoma. OSSM’s impact is growing with every graduating class!

Charles L. Spicer, Jr.,

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FACHE President and Chief Executive Officer of OU Medical System

Jon Hayes, MHA, CMPE Chief Executive Officer of The Children’s Hospital at OU Medical Center

Kris Wallace

Chief Operating Officer OU Medical Center

OU Medical Center 700 NE 13th St., Oklahoma City, OK 73104 oumedicine.com/oumedicalcenter Follow us on Twitter at @oumedicine Like us on Facebook at facebook.com/oumedicine Follow us on Instagram at instagram.com/oumedicine The Children’s Hospital at OU Medical Center 1200 Children’s Ave. Oklahoma City, OK 73104 oumedicine.com/childrens Like Children’s on Facebook at www.facebook.com/OKChildrens For career information, visit careers.oumedicine.com/now-hiring OU Medical Center is Oklahoma’s largest and most comprehensive hospital dedicated to defining medicine with cuttingedge treatments and working toward solutions for each patient, every time. Our 350-bed hospital provides services not offered elsewhere in the state, including Oklahoma’s only Level I Trauma Center. We provide a full range of heart care services at OU Medicine Cardiovascular Institute, the state’s premier center for treating cardiac and vascular patients. We offer the highest level of care for stroke patients when “time is brain,” and provide unmatched neurology and neurosurgery services ranging from the diagnosis and treatment of epilepsy to the most complex and advanced brain surgeries. We also offer

cancer care working alongside Stephenson Cancer Center, including a Gamma Knife Center for treating brain tumors that can’t be treated by conventional methods and a Bone Marrow Transplant Center. With more specialists in more fields than any other hospital in the state, we’re making sure Oklahomans are alive and well. The Children’s Hospital at OU Medical Center has 314 inpatient beds and is the only freestanding pediatric hospital in Oklahoma solely dedicated to the treatment of children. Our pediatric staff blends years of specialized pediatric training with education, research and technology to treat conditions ranging from cardiothoracic and oncology-related illnesses to neonatal specialty care and pediatric solid-organ transplants. Our 93bed neonatal intensive care unit provides the highest level of neonatal care in Oklahoma. The Children’s Heart Center brings cutting-edge research, treatment and surgery to patients with congenital and acquired heart conditions. We have the state’s largest staff of Child Life specialists to help children and families cope with hospitalization, as well as Oklahoma City’s only 24/7 pediatric emergency room. Oklahoma is alive and well, and OU Medicine is at its heart.

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1200 N. Phillips Ave., Suite 2900 Oklahoma City, OK 73104 Phone: (405) 271-3932 Website: www.oumedicine.com OU Physicians is part of OU Medicine, combining academic knowledge and advanced health care. With more than 560 doctors, OU Physicians is the state’s largest physician group. The practice encompasses almost every adult and child specialty. Many OU Physicians have expertise in the management of complex conditions that is unavailable anywhere else in the state, region or sometimes even the nation. Some have pioneered surgical procedures or innovations in patient care that are world firsts and many are conducting groundbreaking research to develop new treatments and cures. More than 175 of our doctors are OU Children’s Physicians. The majority of them are board-certified in children’s specialties, and many provide pediatric-specific services unavailable elsewhere in the state. Many children with birth defects, critical injuries or serious diseases who can’t be helped elsewhere come to OU Children’s Physicians. Oklahoma doctors and parents rely on OU Children’s Physicians depth of experience, nationally renowned expertise and sensitivity to children’s emotional needs. In 2009, OU Children’s Physicians opened a new state-ofthe-art facility on the OU Health Sciences Center campus. A year and a half later, the Children’s Atrium was opened creating a new entrance to not only the children’s physician offices, but the hospital as well. The following year, the final piece of this construction project was completed with the opening of the Samis Education Center, further enhancing the campus’ ability to provide the highest quality education services to faculty, staff and students. Many OU Physicians see patients through specialty centers like The Peggy and Charles Stephenson Cancer Center and Harold Hamm Diabetes Center. The Cancer Center building represents the largest public-private biomedical initiative in Oklahoma history. The 210,000 square-foot facility provides

Brian Lynn Offic Brian Maddy, Chief Executive Officer and Lynn Mitchell, M.D., Chief Medical Officer patient-center care, offering the most advanced cancer detection and treatment technology, the largest and most experienced group of cancer specialists, a wide array of supportive services and an environment that provides a warm and comforting experience for patients and caregivers. Members of the Cancer Center - including faculty from OU Health Sciences Center, OU Norman, OU Tulsa, Oklahoma State University and the Oklahoma Medical Research Foundation - conduct innovative and nationally-funded cancer research in the basic, clinical and population sciences. Harold Hamm serves as the focal point for coordinating and expanding numerous avenues of research, patient care, education and prevention that are required to address the diabetes epidemic in a comprehensive manner. The Center offers outreach efforts throughout the state, partnering with communities and other agencies both inside and outside the University of Oklahoma. The Center was established by the University of Oklahoma with the goal of promoting the wellbeing of all people with or at high risk for diabetes in Oklahoma, regardless of ethnic background or financial status. OU Physicians see patients in their offices at the OU Health Sciences Center and in Edmond, Midwest City and other cities around Oklahoma. When hospitalization is necessary, they often admit patients to OU Medical Center. Many also care for their patients in other hospitals around the metro area. OU Physicians serve as faculty at the University of Oklahoma College of Medicine and train the region’s future physicians. For more information about OU Medicine, including OU Physicians and OU Children’s Physicians, go to www.oumedicine.com. OU Physicians faculty and staff are employed by the University of Oklahoma, one of Oklahoma’s largest employers. The university attracts leading faculty and staff from around the world. To view job opportunities within OU Physicians, go to this site: www.oumedicine.com/ouphysicians/job-opportunities

Member

Tom Gray, President & CEO 655 Research Parkway, Suite 500 Oklahoma City, OK 73104 Phone: 405-319-8150 Fax: 405-319-8168 Website: www.phfokc.com Founded in 1985 with the vision of creating a premier medical center in Oklahoma City, the Presbyterian Health Foundation has invested over $118 million in medical education and research in Oklahoma. This investment has led to medical breakthroughs which touch the lives of individuals and families in communities across the state and nation. It has also brought exciting economic opportunities by positioning Oklahoma at the forefront of genetic research and biotechnology. Proceeds from the 1985 sale of the Presbyterian Hospital were used to create a foundation which would enhance medical research and education in the state of Oklahoma. Trustees of the Presbyterian Hospital continued with the newly formed foundation and believed the potential for excellent health could become the norm, rather than the exception, for all people. Nearly 30 years later, Trustees of the Foundation continue to share a set of values, expectations, and modes of behavior refined under strong leadership and forged by a long history of success that has made a tremendous impact on the people of Oklahoma.

Over the last decade, Presbyterian Health Foundation developed the PHF Research Park which contains 700,000 square feet of wet lab and office space and provides a place for researchers to translate discovery to solutions, putting science to work solving a specific human health need. Following the 2013 sale of the PHF Research Park to the University of Oklahoma, the Foundation has returned to focusing its efforts on supporting scientific research and medical education at the Oklahoma Health Center Campus. The purpose of the foundation is to provide resources and to encourage the development of medical education and research programs, conducted primarily in Oklahoma. The Foundation concentrates its support in four areas: • Medical Research • Medical Education • Community Health Programs • Technology Transfer Researchers, mentors, administrators and leaders in biotech companies are all part of a community of people who bring to life the ideas of PHF’s mission. PHF will continue its mission to support excellent biomedical science where discovery may be translated to therapies that save and enhance human life. Today, the disclosures in good science, evidenced based knowledge, yield brand new widened horizons of human existence.

Member

Susan Adams, President & Chief Executive Officer 1301 NE 14th Street Oklahoma City, OK 73117 Ronald McDonald House and Main Phone: (405) 424-6873 Ronald McDonald House at The Children’s Hospital Phone: (405) 271-3180 Family Room at The Children’s Hospital Phone (405) 271-2215 Website: www.rmhc-okc.org When a child is hospitalized or receiving ongoing medical treatment, we believe the love and support of family is as powerful as the strongest medicine. Unfortunately for most parents, being with a hospitalized child means eating out of vending machines and sleeping in chairs or bearing the expense of hotel rooms. That is why Ronald McDonald House Charities® Oklahoma City is here. Keeping families close . . . when they need it most At 89% of the world’s leading children’s hospitals, families benefit from at least one RMHC Core Program. The Children’s Hospital is served by the 14-BR Ronald McDonald House which has been located at NE 14th St and Lottie for more than 32 years, as well as the 14-BR Ronald McDonald House located in Garrison Tower at The Children’s Hospital that opened in 2015. At our Houses, families can have a bedroom of their own with a comfortable bed, a family-style kitchen with home-cooked meals, and laundry facilities for their personal use. Worried moms and dads can talk to one another, sharing their hopes and fears. For the child who is sick or injured, having a Ronald McDonald House means that they can rest easier, knowing that mom and dad are nearby. The Ronald McDonald Family Room®, located on the sixth floor of The Children’s Hospital, opened in 2008 34

for day-use respite services. Parents can relax and regroup just steps away from their child’s bedside. The positive, comforting environment of all three facilities allows the families to focus on their children’s healing process. Services are available to any family with a child 21 years of age or younger receiving medical treatment in Oklahoma City area, regardless of their economic status. Ronald McDonald House Charities Oklahoma City relies on donors and the community for support of daily operations. Guest families stay at no cost and are never turned away due to the lack of finances. The organization offers career opportunities within the charity, at the Houses and Family Room to help with the daily operations. For open positions, please visit http://rmhc-okc.org/about-us/join-our-team/. Interested candidates should submit a resume to careers@ rmhc-okc.org. Volunteers are the heart of our charity. Individuals or groups can volunteer in either the Houses or the Family Room. Volunteers can help by performing weekly duties such as cleaning, organizing, repair work, maintaining flowerbeds, managing the front desk or performing office work. The organization accepts donated food items and supplies from the public to provide a clean and comfortable environment for all of the guests. Volunteers can donate time through outside fundraisers, at the Houses or Family Room and at annual events such as Walk for Kids and the Red Shoe Gala. Volunteers can also participate through the Guest Chef program at RMHC-OKC. Individuals, small groups or organizations can prepare and serve a fresh-made meal for guest families. Meals may be prepared in the wellequipped kitchen or arranged from a restaurant or deli. For more information about Ronald McDonald House Charities Oklahoma City, please visit www.rmhc-okc. org or call (405) 424-6873.

Member

Dean Gandy, Chief Executive Officer University Hospitals Authority & Trust PO Box 26307 Oklahoma City, OK 73126 Phone: 405-271-4962 Website: www.universityhospitalsauthority.com The University Hospitals Authority and Trust are a state agency and a public trust of the state of Oklahoma. Their mission is to be a catalyst for excellence in medical education, research and health care. Through the leadership of the University Hospitals Authority and Trust, state and federal resources are maximized to ensure a dependable source of revenue for growth, development and ongoing support for programs aimed at improved health for all Oklahomans. Since 1998, the Authority and Trust have invested approximately $900 million in buildings, equipment and programs. The Trust has built or renovated and now manages over 1.6 million square feet of office and clinical space. Here are a few key projects funded by the University Hospitals Authority and Trust:

• OU Physicians Building, home to more than 130 physicians, with expertise in a wide range of medical specialties. • Support for the Clinical Skills Testing and Education Center at the OU Health Sciences Center, offering cutting-edge medical simulation equipment and facilities, as well as a robot-assisted surgical training facility • Support for phase two of the Stanton L. Young Biomedical Research Center, a hub of research activity on the OUHSC campus. • Support for enhancement and expansion of the Dean McGee Eye Institute • Facility enhancement for the OU College of Dentistry, providing important upgrades and technological enhancements

• Construction of the M. Dewayne Andrews academic office tower for the OU College of Medicine • The Children’s Atrium, which serves as the front door for The Children’s Hospital at OU Medical Center and OU Children’s Physicians Building • •Samis Education Center, a three-story, state-ofthe-art facility designed to accommodate a wide variety of meeting needs. • OU Children’s Physicians Building, the first freestanding, pediatric multi-specialty, medical office building in the state, featuring 336,000 square feet of medical office space designed with the needs of young patients and their families in mind.

Member

Jason R. Sanders, MD Senior Vice President and Provost P.O. Box 26901, LIB 221 Oklahoma City, OK 73126 Phone: (405) 271-3223 Website: www.ouhsc.edu

In education, research and patient care, the University of Oklahoma Health Sciences Center is the state’s premier academic health center and regional leader in meeting the challenges of 21st-century health care. The most concentrated source of medical expertise in Oklahoma, the OU Health Sciences Center’s new facilities and new technology -- plus an internationally prominent faculty -- place it at the leading edge of the nation’s institutions of medical education. One of only four comprehensive academic health centers in the nation with seven professional schools, the OU Health Sciences Center serves more than 3,800 students enrolled in more than 70 health professions, graduate and undergraduate programs on the Oklahoma City campus and at the Schusterman Center at the University of Oklahoma-Tulsa. In addition, more than 700 physicians are receiving residency training in Oklahoma City and Tulsa. Research, training grants and contracts, and sponsored program activities at the OU Health Sciences Center totaled more than $120 million

in FY 2013. With a budget of over $870 million, OUHSC employs more than 1,200 full time faculty and 4,000 staff. More than half of all NIH expenditures in the state of Oklahoma result from OU Health Sciences Center research. The OU Health Sciences Center serves as the state’s training facility for physicians, biomedical scientists, nurses, dentists, pharmacists and a wide range of allied health and public health professionals. The OU Health Sciences Center is known for its research programs in cellular and molecular medicine, gene regulation, structural biology, cancer, diabetes, microbiology and immunology, vision, cardiovascular physiology, neuroscience and pharmaceutical sciences. The center’s growing faculty and facilities offer unparalleled opportunities for students, patient care and the development of the biomedical industry in Oklahoma. OU Health Sciences Center-developed technology is advancing the economy of Oklahoma. Companies that commercialize technology created by OU Health Sciences Center researchers have been established in Oklahoma City. OU has become one of the primary centers in the world for genome studies, with the Norman campus contributing to the human genome project and the OUHSC campus providing a number of microbial pathogen genomes. The OU Health Sciences Center ranks second in the world for the number of microbial genomes being sequenced.

Member Two-thirds of all Oklahoma physicians, half of the state’s dentists and a significant percentage of Oklahoma’s other health care professionals earned their degrees from the OU Health Sciences Center. In addition, the seven OU Health Sciences Center colleges are the primary source of continuing education for the state’s health care professionals. The scientists, scholars and clinicians appointed to the OU Health Sciences Center faculty stand at the leading edge of their profession. They not only train the next generation of health care providers and researchers,

With cancer being one of the leading causes of death in the United States, The Peggy and Charles Stephenson Cancer Center opened in June 2011. This cancer center allows the people of Oklahoma to receive world-class treatment without leaving the state and is staffed with some of the nation’s finest cancer physicians. It offers state-of-the-art technology, unparalleled cancer research programs, and bench-to-bedside care.

many are themselves practicing professionals actively involved in improving the lives and health of Oklahomans. The clinical practice of the OU College of Medicine is provided through OU Physicians. These physicians represent the largest multi-specialty medical group in the state with more than 500 physicians, offering almost every adult and child specialty. OU Physicians accepts referrals from across the state and region and care for hospital patients at the OU Medical Center. OU Children’s Physicians is an integral part of OU Physicians.

The Harold Hamm Diabetes Center is a comprehensive treatment, research, and educational facility dedicated to eliminating and controlling the effects of all types of diabetes. The Diabetes Center is at the forefront in diabetes-related research, and OUHSC physician researchers are specialists in diabetes care and utilize cutting edge research for the best treatment available research.

Associate Member

Mark W. Kelly, President and CEO 3001 N Lincoln Blvd Oklahoma City, OK 73105 For all locations visit: https://www.oecu.org/locations/ Phone: 405.606.6328 Website: www.oecu.org Oklahoma Employees Credit Union (OECU) has been happy to help Oklahomans for over 60 years. In 2003, OECU was granted a community charter which opened membership to anyone who lives, works, worships or attends school in the Oklahoma City Metro Area. The financial services industry is rich with innovation and OECU is at the forefront offering digital document signing, Apple Pay™, Touch ID™ and apps for Android™ and iPhone®. If you’re looking for top-rated technology from your financial institution then OECU is right for you. OECU loves to support community efforts around the Oklahoma City Metro. For example, over the last 5 years donations totaling more than $141,000 have been presented to The Children’s Hospital Foundation. OECU also values the importance of keeping your money local and partners with Keep it Local OK, Plaza District and Uptown 23rd on community enhancement initiatives. Don’t be surprised when you find OECU

staff passing out goodies from their Treat Trike and volunteering at events around OKC. In 2012, OECU opened a flagship branch at 3001 North Lincoln Boulevard conveniently located 1.5 miles north of the Oklahoma Health Center Campus. OECU offers two ATMs located on campus. You will find our ATMs inside the OU Medical Center and at the Presbyterian Professional Building. OECU members also enjoy free access to over 900 ATMs across Oklahoma. Currently, OECU has almost half a billion dollars in assets, employs 125 people and offers branch access at over 91 locations across Oklahoma and over 5,000 locations nationwide. OECU serves over 40,000 people who enjoy benefits such as low or no fees on services, higher rates on deposits, and low rates on home or auto loans. To keep your money local and join a community that puts people first, not profits visit www.oecu.org or call 405.606.6328 today.

Associate Member

Autoimmune disease... (Continued from page 9)

5R01 DE018209 from the National Institute of Dental and Craniofacial Research; 5U19 AI082714 and U19 AI056363, 5P01 AI083194, 1U01 AI101934 from the National Institute of Allergy and Infectious Diseases; and 8P20 GM103456, 1P30 GM110766, U54 GM104938, 5P30 GM103510 from the National Institute of General Medical Sciences. Additional funds for OMRF’s research were provided by the American College of Rheumatology Research and Education Foundation/Abbott Health Professional Graduate Student Preceptorship Award 2009, the Sjögren’s Syndrome Foundation and the Phileona Foundation.

Paul L. DeAngelis... (Continued from page 7) hyalose.com and choncept.com. Age: 55. Childhood hometown: Baltimore. Education: Harvard College, bachelor’s in biochemical sciences (He lived in Winthrop House.); University of California-Irvine, doctorate in biological sciences (He studied fertilization in sea urchins, which he harvested himself from the Pacific Ocean.); University of TexasGalveston, postdoctoral work in biochemistry and molecular biology. Spouse: Adrienne, a physician assistant with Integris Health. They met at UC-Irvine and have been married 25 years. Residence: North Edmond. Pastimes: Boxing (He competed on a club team at Harvard.); gardening, including orchids in the house; reading (mostly history and science); and traveling. After meeting with colleagues in Vienna, the United Kingdom and Canada, he, his wife and another couple recently spent a week on a catamaran in the Caribbean, sailing, snorkeling, SCUBA diving and hanging out. Trivial trait: He stays up to 1 a.m. or 2 a.m. every day (“That’s when my brain is most active.”), and gets to work about 10 a.m.