38
RESEARCH DAY
POSTER ABSTRACTS
ADVANCED SPECIALTY PROGRAM RESIDENTS Poster #1 Title: Effectiveness of late maxillary protraction vs. surgery in cleft patients Authors: Allison Kawata, Lamia Binhuwaishel, Jaemin Ko, Xuanyu Lu, Ramon Durazo-Arvizu, Stephen Yen, & Ji Hyun Ahn Faculty advisor: Ji Hyun Ahn Background: Cleft lip and palate (CLP) is the most common facial birth anomaly with 1/950 live birth occurrence rate in the U.S. 22-73% of cleft lip and palate patients develop Class III malocclusion. The standard of care in CLP patients with Class III malocclusion is to advance the maxilla with a Lefort I osteotomy at the completion of adolescent growth. Scarring from previous cleft repair surgeries restricts the amount of advancement that can be performed. Non-surgical orthopedic maxillary protraction using reverse pull headgear can be used at 6-12 years of age. Late maxillary protraction (LMP), a modification of Liou’s alternating rapid maxillary expansion and constriction (Alt-RAMEC) protocol, was developed to treat patients with CLP and Class III malocclusion who would typically be treated with orthognathic surgery. This technique loosens the circum-maxillary sutures to mobilize and advance the maxilla. Purpose: The objective of this prospective study was to compare skeletal and dentoalveolar changes in patients with Class III malocclusion associated with isolated
cleft lip and palate treated with LMP vs. maxillary advancement surgery. Methods: 115 patients were enrolled in the study: 55 were treated with LMP (age 11-14 years) and 60 were treated with surgical maxillary advancement (age 16-21 years). Patients selected which treatment modality they underwent. Records were taken at pretreatment, maximal correction, deband, and 1-year follow-up. Results: Statistical analysis pending. We will analyze significant differences across timepoints for various lateral cephalometric landmarks to determine if LMP produces treatment outcomes comparable to surgical maxillary advancement. Conclusions: Pending. Poster #2 Title: Efficacy of topical ketamine in peripheral neuropathic pain compared to placebo or combination therapy Authors: Mona Albatniji, Bruce Vafa, & Anchita Venkatesh Faculty advisor: Reyes Enciso Background: Neuropathic pain (NP) is the process resulting from a primary lesion or a disease of the somatosensory nervous system. Most common conditions that determine the onset of NP are post- herpetic neuralgia, peripheral diabetic neuropathy, chemotherapy induced peripheral neuropathies, and hereditary neuropathies. Patients with NP experience more frequent and severe sleep disturbances, anxiety and depression which significantly impacts their quality of life. The purpose of this study is to find the efficacy of ketamine to treat the NP and compare with placebo or other combination
The Explorer Journal 2022
therapy. The article is based on meta-analysis systematic review. Low dose ketamine generates effective analgesia in NP cases by inhibiting the NMDA receptors which have a major role in generation of the pain. There is limited proof of NMDAR efficacy to treat NP, however the non-selective NMDR antagonist ketamine is recognized to be the most effective one. Ketamine releases the adenosine in the periphery which is responsible for inhibiting the secretion pro-inflammatory cytokines. Ketamine is applied topically, but it is not clear that result is because of cutaneous structure effect or systemic effects of transdermal administration. Chronic NP was one of the first reported indications for treating chronic pain with ketamine, however current data shows that ketamine has limited efficacy on long term use in cases of chronic pain. Poster #3 Title: Burnout and Fulfillment Amongst California Pediatric Dentists and Dental Residents Authors: Jessica Ton & Alexander Alcaraz Faculty advisor: Alexander Alcaraz Purpose: The purpose of this study is to investigate the prevalence of professional fulfillment and its relation to occupational burnout in California pediatric dentists and dental residents. Methods: A survey was sent to approximately 650 pediatric dentists and dental residents who are members of the California Society of Pediatric Dentistry. The survey utilized the Professional Fulfillment Scale and the Overall Burnout Scale from Physician Wellness Research. Results:
Of the 132 returned surveys, 10.6% of responses were from dental residents, 87.9% are currently practicing pediatric dentists, and 1.5% are retired. Private practice is the predominant primary practice setting (84.1%), with majority of pediatric dentists working more than 30 hours per week (78%). Fifty two percent of respondents were found to have positive professional fulfillment. Based on bivariate analysis, overall negative professional fulfillment is significantly associated with overall burnout (p=0.005). Participants with positive professional fulfillment are less likely to have burnout after adjusting for work hours per week and practice years (OR=0.02, 95% CI=0.001 – 0.33, p=0.006). Conclusion: Pediatric dentists and dental residents in California who have positive professional fulfillment are shown to be less likely to experience occupational burnout compared to those who had negative professional fulfillment. Poster #4 Title: Quality of Life in Adolescents with Cleft Lip and Palate Authors: Cathrine Fong, Alexis Johns, Bocheng Gu, Cynthia Gong, Amarjit Dass, & Stephen Yen Faculty advisor: Stephen Yen Purpose: This study aimed to describe the quality of life in youth with cleft lip and palate (CLP) based on medical and sociodemographic variables. Methods: Participants with CLP completed the Youth Quality of Life – Facial Differences, which yields 5 Perceptual subscales: Positive Consequences, Coping, Negative Consequences, Negative Self-Image, and Stigma. Multi-
