11 minute read
New Products
Chromatography
Advertisement
As the latest addition to the Thermo Scientific Vanquish product family, the Vanquish Flex ultra high-performance liquid chromatography (UHPLC) system is designed for high speed, resolution and sensitivity, allowing users to perform biocompatible analysis to obtain high quality and consistent data. By incorporating an integrated modular design, users have the ability to mix and match modules depending on the demands of the application. Additionally, the system provides sharp peaks at high throughputs, allowing more data to be analyzed in less time. Data quality is ensured via the robustness and repeatability of the system to ensure that large sample sets can be analyzed for comparison during QC protocols. Other key features include a new quaternary gradient pump module, excellent performance operating at 1,000 bar maximum pump pressure, with flow rates of up to 8 mL/min to allow for high-resolution separations and application flexibility. Moreover a new fluorescence detector for increased sensitivity complements the absorbance detector module for high sensitivity and extended linearity and the new charged aerosol detector module for non-volatile compounds. To complement the new Vanquish Flex system, the new Thermo Scientific SMART Digest kit is a new protein digestion tool that provides sensitive and fast analyses, while the Thermo Scientific AppsLab library of analytical applications is a fully searchable online method repository that offers protocols, method information, chromatograms and all the information to run, process and report an analysis. Web: www.thermoscientific.com/Vanquish
Blender
The Stomacher® 4500 BAM laboratory blender from Seward Ltd. is specifically designed for largevolume food testing procedures, such as the FDA’s Bacteriological Analytical Manual (BAM), in which 375g composite samples are required for the microbiological analysis of food. Consequently, the new large volume Stomacher enables food manufacturers to combine 15 x 25g (375g) analytical units, rather than testing each unit individually, so you save time when analyzing lower risk food products. Combined with the Seward 400 Circulator, it provides food laboratories with a high performance blender capable of homogenizing sample volumes ranging from 1,000 to 4,500mL. Highly efficient, it also has programmable settings to ensure the best preparation protocol is used for microbial extraction, depending on the food sample under analysis. The blender comes with a range of accessories including standard (65 microns thickness; coded BA6042) and heavy duty (80 microns thickness; coded BA6042/HD) Stomacher bags, large size bag racks and clips. Web: www.seward.co.uk
Columns
The Thermo Scientific ProSwift C4 RP-5H is a new column for liquid chromatography-mass spectrometry (LC/MS) analysis that uses a unique capillary design to offer labs with limited samples and complex mixtures a fast and high-resolution solution for the identification of protein samples, facilitating high sensitivity proteomics and biotech applications. The column incorporates a exceptionally designed, low-pressure C4 monolith with a porous structure, enabling faster low-flow separations without sacrificing resolution compared with typical porous bead based media. The new column’s porous copolymer gives the flow channels higher permeability in the stationary phase than particulate columns, resulting in increased separation efficiency. Due to this structure, smaller i.d. columns of 50 μm can be used for analyses, increasing sensitivity. Additionally, the new monolith uses a butyl (C4) methacrylate co-polymer that is less hydrophobic than PS-DVB columns, meaning there is less column fouling. This is important for MS users where sensitivity is higher compared to UV and carryover can cause interference. Web: www.thermoscientific.com/proswift.
COMPANY & ADVERTISER INDEX
COMPANY PAGE WEBSITE
Aeterna Zentaris Inc. ......................... 7.............................. www.aezsinc.com BioAlberta......................................... 6.......................... www.bioalberta.com Calgary Scientific Inc.......................... 6..................www.calgaryscientific.com Centre for Drug Research and ...................................................................... Development..................................... 6.....................................www.cdrd.ca ChildrensMiracleNetwork............... 17..www.childrensmiraclenetwork.ca Chemical Institute of Canada............ 5............................. www.cic2015.ca Clementia Pharmaceuticals Inc............ 7................www.clementiapharma.com Dalton Pharma Services..................... 7................................www.dalton.com EMD Millipore .................................. 16......................www.emdmillipore.com Eppendorf....................................... 20...................... www.eppendorf.com ESSA Pharma Inc............................... 6....................... www.essapharma.com Immunovaccine Inc............................. 7...........................www.imvaccine.com LifeLabs ............................................ 5...............................www.lifelabs.com Mandel/Wyvern .............................. 11..............................www.mandel.ca McGill University ............................... 3................................... www.mcgill.ca McMaster University.................................................................................... Biointerfaces Institute........................ 3..........www.biointerfaces.mcmaster.ca Ontario Institute for Cancer Research . 4..................................www.oicr.on.ca PCR Max ......................................... 16.............................www.pcrmax.com ProMIS Neurosciences....................... 7.......... www.promisneurosciences.com ProNAI Therapeutics Inc..................... 6................................www.pronai.com Qu Biologics Inc................................. 7.........................www.qubiologics.com Response Biomedical Corp.................. 6....................... www.responsebio.com Seward............................................. 6............................ www.seward.co.uk Telesta Therapeutics Inc. ................... 7............ www.telestatherapeutics.com Thermo Scientific.............................. 15................ www.thermoscientific.com Transition Therapeutics Inc. ................ 6.........www.transitiontherapeutics.com VWR ................................................ 2...........................https://ca.vwr.com
NEW PRODUCTS
RC_lab_new:Layout 1 12/19/2012 10:01 AM Page 1
Thermal Cycler
The quad is back as PCRmax (a Bibby Scientific Company) has launched the Alpha Cycler 4, a thermal cycler that is capable of performing four totally independent runs simultaneously, all within a compact instrument footprint. Performing high throughput PCR can be a costly and resource intensive process. The Alpha Cycler 4’s innovative ‘quad’ bay design and smart software features overcome these limitations by expediting PCR and easing operation, while delivering precise DNA amplification. Configurable in any combination of 96 to 384 well formats across its four bays, the Alpha Cycler 4 system is ideally suited to high throughput, standard throughput and multiple user environments. Advanced software features such as ‘Recently Used Programmes’ allows users to quickly access their most commonly used protocols without the need to navigate through folders to find them. A novel program wizard generates protocols based specifically from users primer sequence and template source, while individual logins ensure this time-saving feature is available to multiple users and secures user protocols to their specific login should they wish. Greater connectivity and real-time monitoring with a hand-held reporting device (such as a smart phone or tablet) then enables users to track their process to ensure that data quality never suffers. Finally active sample cooling delivers sharper and minimal nonspecific amplification. Web: www.pcrmax.com.
SRC103
I wish to receive/continue to receive a complimentary subscription to LABORATORY FOCUS Yes No Format Preference: Print option Digital option
Name: ____________________________ Job Title: _______________________________ Company: _________________________ Dept: _________________________________ Business Address : _______________________________________________________ City: _________________________ Prov: ________ Postal Code: ___________________ Telephone: ___________________________ Fax: ________________________________ E-mail: ___________________________________________________________________
On occasion, LABORATORY FOCUSwill send third-party information on products & services related to the lab and life science industries. These may be cancelled at any time. Please check here if you do NOT wish to receive these.
JOB TITLE
70 Laboratory Dir. / Mgr. 71 Laboratory Purchaser 72 Laboratory Technician 73 Research Scientist 99 Other: ____________________ ____________________________
COMPANYs PRIMARY BUSINESS ACTIVITY
50 Industrial Laboratories 51 Academic Laboratories (except medical) 52 Medical Laboratories and Pharmacies within Hospitals and Universities (clinical and research)
55 Government Laboratories 54 Pharmaceutical Companies including Pharmaceutical Wholesalers 57 Private (Independent) Lab 99 Other: ____________________ ____________________________
C75 Primary Work Field
10 Aerospace 11 Automotive 12 Biological Sciences 13 Chemicals 14 Electrical/Electronics 15 Energy 16 Environmental Science 17 Food/Beverages/
Agriculture 18 Forensics 19 Genetic Technology 20 Material Science
C87 Products Used in your Laboratory
A Analysis Instruments B Basic Lab Equipment C Chemicals/Biochemicals D Chromatography – Gas E Chromatography – Liquid F Filtration, Water Purification G LIMS H Liquid Handling & Sample Prep I Microscopes, Optics, Cameras J Safety & Hygiene K Spectroscopy L Testing Systems/Equipment M Vacuum Equipment
21 Clinical Sciences 22 Metallurgy 23 Paints/Coatings 24 Paper/Pulp 25 Petroleum 26 Pharmaceuticals 27 Plastics/Rubber 28 Supplier – Instruments/
Consumables 29 Manufacturing 30 Construction 99 Other: ____________
C90 To subscribe to our e-mail newsletters, please check
Bioreactor
EMD Millipore, the life science business of Merck KGaA has added to its stirred tank bioreactor portfolio (from 3 to 2000 litres) with the Mobius® 2000 litre single-use bioreactor. The new bioreactor features a pull-out drawer and self-deploying bag, making Flexware® assembly installation and inflation safe and easy. This design minimizes operator intervention and requires no hoist during Flexware® assembly installation and removal. A patent-pending baffle design creates superior, homogenous mixing. The 5:1 turndown ratio allows users to inoculate and harvest at lower volumes, creating a wider, more flexible process window for seeding, growth, and collection strategies. The bioreactor also includes an external SensorReady loop connected to the Flexware® assembly via Lynx® connectors to provide greater flexibility for process monitoring and control. Unlike traditional bioreactors in which sensors are inserted into the Flexware® assembly, the SensorReady loop enables users to incorporate additional sensors without modifying the Flexware® assembly. The Mobius® 2000 litre single-use bioreactor can be supplied as a fully-integrated system with intuitive GMP-compliant software that reduces the learning curve for operators and allows for easy integration into plant automation strategies. The automation is simple and enables users to easily customize and control their processes. For customers with plant-wide common automation strategies, the single-use bioreactor can be integrated into third party automation platforms. Web: www.emdmillipore.com
NEW PRODUCTS
Liquid Chromatography
The Waters® ACQUITY® Arc™ System is a quaternary liquid chromatograph that gives analytical laboratories running established LC methods an alternative to replicating or improving their separations performance. This new addition to the ACQUITY product line is specifically engineered to give analytical scientists a single LC platform that can enable them to efficiently transfer, adjust or improve their methods regardless of the LC platform on which they were developed. To date, scientists working with established methods haven’t had an LC platform versatile enough to bridge the gap between HPLC and UPLC®. With the introduction of the ACQUITY Arc System, and its enabling Arc Multi-flow path™ technology, scientists now have the ability to emulate the gradient dwell volume and mixing behavior of various LC systems. By selecting the appropriate fluidic path, the ACQUITY Arc System can easily emulate a variety of HPLC systems without altering the method’s gradient table, or provide UHPLC performance with the flip of a switch. In addition to replicating established HPLC assays without altering the gradient table, the ACQUITY Arc System can enable improved chromatographic performance of methods by leveraging 2.5 to 2.7 micron particle column technologies, as well as support previously developed applications on 3 to 5 micron HPLC columns. Web: www.waters.com/arc.
Fume Hoods
Air Science introduces its new Purair ECO™ line of energy-saving ductless fume hoods. Designed for both chemical and particulate protection over a broad range of laboratory and industrial applications, the Purair ECO minimizes stress on facility HVAC systems without compromising protection for personnel and the environment. The Purair ECO is available with a choice of controllers including the company’s new ECOair™ touchpad control with color display interface. An optional BACnet network interface connects all cabinet control, monitoring and alarm functions to an open-source facility monitoring system. The system is based on an industry-wide, non-proprietary ASHRAE compliant protocol for green building management. It comes available in five standard sizes from 30” wide to 69” wide. Web: www.airscience.com
High Throughput Prep kits
The NEXTflex™ mtDNA-Seq Kit offers a robust method for mitochondrial DNA (mtDNA) isolation and construction of mtDNA libraries for Illumina-compatible targeted or whole mitochondrial sequencing. The NEXTflex mtDNA-Seq Kit incorporates an mtDNA isolation procedure which selectively digests linear nuclear DNA, facilitating the isolation of mtDNA from genomic DNA; enriching the mitochondrial genome 100 to 350 times. After mtDNA isolation, mtDNA single read or paired-end Illumina-compatible mtDNA-Seq libraries are constructed using the reagents included in the kit. The availability of up to 96 barcodes allows for high-throughput multiplexing to reduce sequencing costs. Web: www.biooscientific.com
Metal Analyzers SPECTRO
Analytical Instruments has introduced two new SPECTROLAB Arc/Spark optical emission spectrometers for high-performance metal analysis in metals industry research and development (R&D) and process/quality control. The new hybrid SPECTROLAB metal analyzer combines analog photomultiplier tube (PMT) detectors with digital charge coupled device (CCD) technology for ultra-accurate simultaneous measurements in R&D, trace metal measurement, and precious metals analysis. Additionally, the new all-CCD technology SPECTROLAB spectrometer provides speed, accuracy and flexibility for process control and QC of fabricated and finished goods. Features of both new high-performance metal analyzers include ultralow limits of detection with improved background correction. Depending on application and analytes, SPECTROLAB can easily ascertain trace values in single parts per million (ppm). The two devices also offer elemental flexibility, in most cases eliminating hardware reconfigurations. An optional software-extendable configuration enables changes to the elemental setup without requiring calibration. Web: www.spectro.com/lab
Chromatography and Mass Spectrometry
The Prelude LX-4 MD is the newest addition to the family of Thermo Scientific chromatography and mass spectrometry instruments and software for the clinical lab. Clinical laboratories requiring high-throughput separations for their LC-MS assays now have access to this fourchannel, high-performance liquid chromatography (HPLC) system. Listed with the FDA as a Class I medical device for general clinical use, the Thermo Scientific Prelude LX-4 MD HPLC quadruples the productivity of a single-channel HPLC delivering up to four separations in a single instrument. This helps to streamline LC-MS workflows and reduce mass spectrometer idle time. The four channels can run identical or different LC-MS assays simultaneously, which provides flexibility for varying clinical separations and maximizes mass spectrometer utilization. Web: www.thermofisher.com
Data logger
T&D Corporation introduces its new two channel temperature data logger model TR-71nw. The TR-71nw supports automated, error-free data collection, remote monitoring and alerting with a simple Ethernet LAN connection. The TR-71nw measurement range is -40 to 110°C (Supplied Sensor) or -60 to 155°C (Optional Sensor: Fluoropolymer Coated Type) with resolution of 0.1°C. Measurement units can be in centigrade or fahrenheit. Other features include the aforementioned two channel temperature monitoring, automatic uploads to TandD’s free web storage Service through the internet and a free ThermoWeb App for both iOS and Android. Web: www.tandd.com
