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R&D News

Liquid Handling

Diba Industries Inc., a provider of precision fl uid handling solutions for diagnostic, analytical and medical device manufacturers is launching its 10-32 cone-tip ClickN-SealTM Ultra at Pittcon 2015. The 10-32 cone-tip Click-N-SealTM Ultra connects 1/16’’ OD semirigid tubing, such as PTFE, ETF, FEP and PEEK, in to 10-32 conical ports. The fi tting is suitable for pressure ratings up to 2000psi (140 bar) and is constructed from PEEK for enhanced chemical resistance. The Click-N-SealTM Ultra has a space saving compact head design and ensures leak free connections. The fi tting is hand-tightened until the correct torque is reached, at which point the cap clicks, preventing both over- and under-tightening of the fi tting. The fi tting can be unscrewed and re-used making it suitable for multi-use applications. web: www.dibaind.com

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Microscopes

ZEISS introduces its new scanning electron microscope, the MultiSEM 505. The new system features 61 beams working in parallel, making it possible to acquire 61 images in parallel. Additionally, the MultiSEM 505 offers a capture speed of 1,220 megapixels per second at a pixel size of 4 nm. This high acquisition speed is used for imaging neural tissue in brain research where it is now possible to observe much bigger samples than before. The SEM is designed for continual operation and fi tted with the intuitive ZEN Software. web: www.zeiss.com

Sample Handling

Omega’s new TCL-10 series is simple to operate and can keep your sample at a low temperature for long periods. Cooling causes no mess or contamination. 20 sample compartments are in each block, sizes 0.2 ml to 2 ml and the compartments can easily be changed when different sizes are needed. The unit can also use the ceramiccoated aluminum beads to accommodate various sample vials at the same time. There are two different models: TCL-11 the analog device and TCL-12 the digital device.The TCL-10 is ideal for both the laboratory and pharmaceutical development. Simply plug it in, turn it on, and put the sample in. web: www.omega.com

Chromatography

Laboratories characterizing monoclonal antibodies (mAb) now have additional hydrophobic interaction chromatography (HIC) selectivity options, thanks to the expanded family of Thermo Scientifi c MAbPac HIC HPLC columns. The new MAbPac HIC-20 and MAbPac HIC-Butyl columns offer additional selectivity options for characterizing mAb oxidation variants, intact mAbs, mAb aggregates or fragments and antibody drug conjugates (ADCs). The new columns are also designed for compatibility with organic solvent and aqueous mobile phase, as well as for rugged stability and very low carry-over. web: www.thermoscientifi c.com

Genomic Tools

SYGNIS AG launches its TruePrime™ Single Cell WGA kit for whole genome amplifi cation (WGA) from single cells. Single cell analysis has become one of the most exciting applications in next generation sequencing (NGS) today, as it provides accurate analysis of cancer related mutations in cells, taken via biopsies, from different locations in a tumour or characterization of the status of a patient in personalized medicine. Based on the recently discovered primase TthPrimPol, SYGNIS’ TruePrime™ technology stands for a revolutionary way to amplify the amount of DNA or RNA in a sample. While the current gold standard in MDA needs short pieces of DNA (oligonucleotides) to start off whole genome amplifi cation, TruePrime™ does not need any synthetic random primers. The resulting benefi ts of this innovative approach are enormous and include complete absence of common artifacts linked to the use of oligonucleotides and a reduced amplifi cation bias in genome coverage compared to methods using random synthetic primers. Moreover, TruePrime™ is easy to use and works perfectly well with all commonly used NGS platforms such as Illumina and IonTorrent. web: www.sygnis.com

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COMPANY PAGE WEBSITE

aMric .............................................. 4 ................................... www.amric.ca aptose biosciences inc. .....................5,6 ............................www. aptose.com briacell therapeutics inc. ................... 6 .............................. www.briacell.com brooks life Science Systems ............. 16 ..............................www.brooks.com canadian society for chemical .................................................................... technology ....................................... 5 ....................www.chem-tech.ca/cct children’s miracle network............ 17 ..www.childrensmiraclenetwork.ca cipher pharmaceuticals inc. ..............5,6 ...................www.cipherpharma.com cole –parmer ................................... 16 .......................... www.coleparmer.ca Diba industries inc. .......................... 15 ..............................www.dibaind.com eppendorf ....................................... 20 .......www.eppendorf.ca/automation GSK ................................................. 3 ...................................... www.gsk.ca Mettler toledo.................................. 16 ........................................ca.mt.com neOMeD ........................................... 3 ................................ www.neomed.ca northern lipids inc. ........................... 6 .....................www.northernlipids.com Omega ............................................. 15 .............................. www.omega.com OncoGenex pharmaceuticals inc. ......... 5 ......................... www.oncogenex.com Panasonic ....................................... 19 ....................................................... .............................................................us.panasonic-healthcare.com/twinguard proMetic life Sciences inc. ................. 5 ............................www.prometic.com pronai therapeutics inc. .................... 5 ................................www.pronai.com Simon fraser university ..................... 3 .......................................www.sfu.ca Sirona biochem corp. ........................ 6 ....................www.sironabiochem.com Structural Genomics consortium ........ 1 ................................www.thesgc.org SYGniS aG ....................................... 15 ...............................www.sygnis.com thermo Scientifi c .............................. 15 ................ www.thermoscientifi c.com vwr ................................................ 2 .............................www.ca.vwr.com wyvern scientifi c/mandel ................ 9 ...............................www.mandel.ca ZeiSS .............................................. 15 .................................www.zeiss.com Zymeworks inc. ................................ 5 .........................www.zymeworks.com

new Products

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Sample Measuring

The Mettler Toledo MP50 Excellence is a flexible instrument for the automatic determination of melting points and melting ranges up to 300 °C. The instrument allows four samples to be measured simultaneously for higher efficiency. The intuitive one Click® colour touch screen provides fast and secure operation to the user. Accurate measurements are ensured thanks to temperature-accuracy specifications and compliance with current standards including Ph. Eur., USP, and more. Visual camera observation and digital image analysis guarantee that the result values are reliable. The high resolution videos recorded during the measurement can be repeatedly played back on the instrument at any time. This allows you to check unexpected results by visually verifying the measurements. web: ca.mt.com

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Sample Collection

Brooks Life Science Systems introduces the SampleStoreTM II SE, an extension of its SampleStore II automated storage solutions portfolio that can manage a wide range of consumable types. The modular SampleStore II SE solution is designed for libraries of 50,000 to 300,000 1.4 ml tubes at temperatures of -20° C to +20° C. It is scalable with expansion modules to meet future needs and can fit through a standard laboratory door. The system’s Strata™ user interface, used across all of Brooks’ automated storage systems, makes it easy to store and retrieve samples. The Strata software also enables comprehensive sample information management, scalability, and integration with laboratory information management systems (LIMS). web: www.brooks.com

Peristaltic Pump

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Reduce setup time with the Catalyst™ by Masterflex FH Series peristaltic pumps from ColeParmer. The integrated pump and drive systems arrive fully assembled and ready to run. Save additional time when changing tubing—30 seconds is all it takes. Tubing occlusion is automatic when the pump head is closed. The interlock switch powers unit down when pump head is opened while the unit is running. The Catalyst FH100 Precision Peristaltic Pumps offer an intuitive keypad to quickly increase or decrease flow. View RPM on digital display for accurate control and repeatability. Purge tubing before and after use with reversible motor. For automated processes, remote control is standard. Catalyst FH100D Digital Peristaltic Dispensing Pumps display all operational parameters on the LCD for at-aglance monitoring. Programmable dispensing modes include volume, time, or copy, with convenient programmed delay between cycles. These pumps can be programmed in seven languages. Catalyst FH100M Digital Multichannel Peristaltic Pumps provide multiple flow channels in a single pump. Their cartridge design enables quick tubing changes—and eliminates the hardware of other multichannel designs. Select from 4, 8, or 12 channel models. web: www.coleparmer.ca

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