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Pharma Notes

Pharma Notes

Shin-Etsu Silicones

Shin-Etsu Silicones of America’s newest HCR (High Consistency Rubber) product line – Sil-XShin™ Silicone Elastomers are specifically engineered for extruded tubing and profiles. SilX-Shin Silicone Elastomers are available in a wide range of Shore A Hardness from 30 to 80 and come in a convenient 10:1 ratio of base compound to catalyst. The most unique advantage of the Sil-XShin product line is that one universal catalyst can be used with each of the six bases, providing ultimate flexibility. The Sil-X-Shin series has a single, universal catalyst that cures any of the six bases with less than 10 per cent of the composition. Sil-X-Shin Silicone Elastomers are USP Class VI compliant, and their platinum, addition-cure chemistry produces a tight surface finish with few residual by-products.

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www.shinetsu.co.jp

Batch Controller

The new Mettler Toledo IND780 stand-alone batch controller combines advanced batching control technology while adhering to the ISA SP-88 Batch Standard. The IND780 batch optimizes batch processes with consistent, accurate material transfers, to minimize material waste and improve batch quality. The flexible stand-alone terminal can be used for single or multi-scale batching applications. With the IND780 batch, users can take control of manual processes with dependable recipe management and the ability to handle 999 materials. Tolerance checking, material identification via bar-code input, and operator prompting all help to ensure the operator is guided through each batch.Multi-material automatic batching control handles up to 28 automatic materials with recipespecific control, including conditional control tasks, go-to commands, recipe re-scaling, timing functions, and control of discrete inputs and outputs to allow the controller to interact with other equipment in the process.

www.mt.com

Slide Imaging System

PerkinElmer Inc. launches the VectraTM 2 automated slide imaging system, a turnkey platform that allows true walk-away batch processing of up to 200 tissue sections at a time. Additionally, the Vectra™ 2 addresses the need of scientists focused on biomarker research, pharmaceutical development, clinical research and tissue application test development for validated tissue labeling and automated scoring methodology. The new platform adds HistoRX’s AQUA® technology to Vectra’s unique multispectral and image analysis capabilities. Its unique multispectral capabilities, coupled with the powerful image analysis tool inFormTM, can be used to explore even the most demanding of today’s tissue analysis problems, from multi-analyte in situ cytometric analysis and cell phenotyping to stereology-like analyses of tissue disease states. The technology provides greater than 97 per cent inter- and intra-assay coefficient of variation, giving researchers assurance in the quality of their results. The system supports both tissue sections and tissue microarrays (TMAs) with ease and offers a slide hotel for batch scanning of up to 200 slides. The Vectra platform is empowered by the same multispectral imaging technology that drives over 400 NuanceTM cameras sold to date, giving researchers the ability to analyze multiple fluors/chromagens in a sample, quantifying each separately and accurately.

www.perkinelmer.com

Vessels

The Thermo Scientific CryoExtra™ vacuum-insulated, stainless steel vessels are available in four different sizes, from 407 litres to 1,630 litres, accommodating both vapour and liquid-phase storage. These containers minimize top-to-bottom temperature variation, preserving the integrity of critical cryogenically frozen samples. Its innovative lid and neck design, combined with advanced temperature monitoring, reduce temperature fluctuations that occur due to lid openings. Furthermore, the microprocessor-based LN2 level control ensures that liquid nitrogen levels are tightly controlled, and the de-fog function allows easy, pushbutton sample identification.With the ability to store up to 90,000 1.2 – 2.0 mL vials, the largest of the four CryoExtra models (1,630 liter) has the same external footprint as the 1,350 liter unit. All four CryoExtra containers can accommodate both vertical and horizontal racks, and the Thermo Scientific racking solutions are specifically designed for this vessel configuration, further maximizing capacity.

www.thermoscientific.com

MILLIPLEX® MAP kit

EMD Millipore launches three MILLIPLEX® MAP kits for cellular metabolism. Based on the Luminex® xMAP® assay technology platform and cellular metabolism antibodies from MitoSciences®, the MILLIPLEX® MAP kits enable fast, sensitive, simultaneous quantification of multiple cellular metabolism biomarkers involved in fatty acid oxidation and the pyruvate dehydrogenase complex. Each kit provides highly validated and characterized cellular metabolism immunoassay antibodies, all necessary reagents, and optimized protocols.

www.emdmillipore.com

Ultracentrifuges

New Optima X Series preparative ultracentrifuges from Beckman Coulter, Inc. incorporate an array of contemporary technical features to enhance the user experience and increase productivity. With a large touchscreen display, the Optima X Series product offers a selection of nine languages while real-time graphing plots speed and temperature over time as a run progresses. Enhanced remote control capabilities allow the ultracentrifuges to be monitored from a personal computer or a smart phone. When powered on but not running, the unit requires the same energy as a 60-watt incandescent bulb, further increasing energy efficiency. Optima X Series ultracentrifuges reach a maximum speed of 100,000 rpm and generate forces up to 802,000 x g. Optima X Series instruments are available in two models – the XE, which delivers all of the basic features required to quickly set up and complete a run, and the XPN, which includes all features of the XE plus networking capability, on-board simulation tools and a variety of customizable security and tracking features. The XE is available in 90,000 and 100,000 rpm configurations, while the XPN is offered in 80,000, 90,000 and 100,000 rpm configurations.

www.beckmancoulter.com

NEW PRODUCTS

96-Well DispoEquilibrium DIALYZER™

The Harvard Apparatus 96Well DispoEquilibrium DIALYZER™ provides simple and reliable techniques to analyze up to 96 equilibrium dialysis chambers simultaneously on disposable dialysis plates. These ready to use equilibrium dialysis plates are convenient and cost effective tools for ligand binding experiments including serum protein binding, protein-drug binding, protein-protein binding and protein-DNA binding assays. Each test well in the plate consists of two chambers separated by a regenerated cellulose membrane with a molecular weight cut off of either 5,000 or 10,000 Daltons. Each chamber holds up to 300μl of sample or buffer. To decrease the dialysis time, the plate needs to be rotated through 360° in a vertical position. Harvard Apparatus can also supply a one or two plate rotator or an eight plate rotator with temperature control.

www.harvardapparatus.com

RTR-505V Wireless Logger

T&D Corporation introduces its new RTR505V Wireless Logger. The RTR-505V can measure DC voltages from 0 to 22VDC with accuracy of ±0.5mv and can measure voltage directly or from the output of a wide variety of sensors and instruments. The RTR-505V features a large LCD display, capacity for 16,000 readings, IP64 water resistance and up to four years battery life with the “L” version. Compatible with all TandD RTR-500 Series Wireless Data Collectors, the RTR-505V can be seamlessly integrated into a wireless network with other logger types. They can be monitored locally, through a cellular phone system, or anywhere in the world over the Internet. Advanced features include real-time monitoring and warning notifications. The communication range is up to 500 ft. which can be extended with the use of a repeater.

www.tandd.com

Titrator

JM Science’s AQUACOUNTER® Volumetric Karl Fischer Titrator (AQV-300) is reliable, easy-to-use and has performance features which allows measure of moisture content from low to high concentrations quickly and accurately. Measurements are simple and routine with unsurpassed precision. The AQV-300 has six built-in calculation modes to accommodate solid, liquid and gas samples. It includes a statistics package with one-touch calculations. Four files with preset conditions can be stored in memory and allows instant recall of data for up to 20 samples. A built-in detector monitors titration status and a direct key access allows entry of titration parameters. This compact unit with a very small footprint has balance and computer interfaces for GLP and ISO documentation and it is CE approved. The titrator comes with DVD training movie, plasticized QuickStart guide for use in the lab, paper and pdf manual. Also included, complete accessories, download software for transferring results to a laptop or PC, RS-232 cable, and AQUACOUNTER® KF Reagent starter kit.

www.jmscience.com

DNA Barcodes Aids

The NEXTflex-96 DNA Barcodes aids next generation sequencing by increasing throughput using barcoded indices allowing users to pool multiple library preparations in a single flow cell lane. The NEXTflex-96 DNA Barcodes accomplish this by providing 96 indexed adapters, each of which contains a unique 8 nt sequence. The indices are designed to be error resistant and allowing for proper differentiation between samples. Using the NEXTflex-96 DNA Barcodes, the index is added to the sample during the adapter ligation step, allowing PCR amplification to be reduced or eliminated, thus minimizing amplification-based bias and preventing poor reads from single base errors introduced during PCR. These barcodes can be used to multiplex genomic DNA, RNA and ChIP sequencing libraries.

www.biooscientific.com

Fume Hoods

Air Science introduces its new Purair ECO™ line of Energy-Saving Ductless Fume Hoods designed for both chemical and particulate protection over a broad range of laboratory and industrial applications. The Purair ECO is available with a choice of controllers including the company’s new ECOair™ touchpad control with color display interface. An optional BACnet network interface connects all cabinet control, monitoring and alarm functions to an open-source facility monitoring system. The system is based on an industry-wide, non-proprietary ASHRAE compliant protocol for green building management. The Purair ECO is available in five standard sizes from 30” wide to 69” wide.

www.airscience.com

COMPANY & ADVERTISER INDEX

COMPANY PAGE WEBSITE

BioTalent Canada ............................... 6...............................www.biotalent.ca Beckman Coulter .............................. 15................. www.beckmancoulter.com Caledon Laboratory Chemicals ......... 4.....................www.caledonlabs.com Canadian Food Inspection Agency.... 11 ................... www.inspection.gc.ca Chemical Institute of Canada............ 6............................www.cheminst.ca EMD Millipore .................................. 15......................www.emdmillipore.com Eppendorf....................................... 20...................... www.eppendorf.com GE Healthcare.................................. 16.....................www.gehealthcare.com IsotechnikaPharma Inc. ...................... 6.........................www.isotechnika.com Kane Biotech Inc................................ 6........................www.kanebiotech.com Meile Professional......................... 5, 7............ www.mieleprofessional.ca MethylGene Inc. ................................ 6........................ www.methylgene.com Mettler Toledo.................................. 15....................................www.mt.com Miraculins Inc.................................... 6.......................... www.miraculins.com PerkinElmer...................................... 15....................... www.perkinelmer.com Shin-Etsu Silicones ........................... 15.......www.shinetsu.co.jp/e/index.shtml Thermo Scientific.............................. 15................ www.thermoscientific.com VWR ............................................... 19................................ www.vwr.com Wyvern Scientific ............................ 2....................... www.wyvernsci.com Zymeworks Inc. ................................. 6.........................www.zymeworks.com

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