New Products

Plate reader system

Promega Corporation has launched the GloMax® Discover, an integrated multimode detection plate reader system. Together with the company’s cell and biochemical assay portfolio, GloMax Discover offers scientists an integrated system to easily study cell signaling and metabolism, while monitoring cell viability, apoptosis, and cytotoxicity, or to study gene expression with a wide variety of reporter assays. The system offers a broad range for both strong and weak bioluminescence experimental samples, with luminescence sensitivity and low well-to-well cross talk, enabling users to generate more usable data from each experiment. GloMax Discover also provides fi lters for fl uorescence intensity, BRET, FRET, fi ltered luminescence and UV-visible absorbance measurements. Likewise, the system’s software provides quick and easy navigation through the control options, preloaded assay protocols, and drag-and-drop protocol customization. Exporting results is simple, with a variety of options including exporting to a local data network, external fl ash drive, internet cloudbased server, and Laboratory Information Management System (LIMS). web: www.promega.com

UPLC System

Waters Corporation introduces its new Waters® ACQUITY UPLC® MClass System, an industry-fi rst nano- to microscale UltraPerformance LC® (UPLC®) system rated for 15,000 psi operation. Coupled to Waters mass spectrometers, the system delivers the sensitivity to quantify and to identify vanishingly small concentrations of key molecules. The ACQUITY UPLC M-Class System is ideally suited for a broad range of applications including proteomics, metabolic profi ling, metabolite identifi cation and pharmacokinetic studies. Its new 15k psi-capable ACQUITY UPLC M-Class Columns tap the potential of sub-2-micron particle technology, yielding faster separations, greater peak capacities and increased levels of sensitivity. web: www.waters.com

Headspace sampler

Shimadzu Scientifi c Instruments has launched the HS-20 Series of headspace samplers. The HS-20 Series consists of two models: a Loop model for the traditional static headspace methods, and a Trap model, which adds the dynamic headspace technique for applications requiring greater sensitivity. The HS-20 Series is ideal for repeatability through its precise control of gas fl ow rates, and a mechanism that allows a sample vial to enter the oven from the bottom. This technique minimizes heat loss and thermal instability during the equilibration step. The oven can be heated to 300 °C, enabling accurate analysis of higher-boiling compounds. Additionally, both models have been engineered with a short, inert sample pathway to minimize carryover from one sample to the next. The HS-20 Series tray holds up to 90 sample vials. It accommodates both 10-mL and 20-mL headspace vials within the same sequence without the need for special attachments. The open architecture of the HS-20 tray provides easy access to all vials for loading and enables stress-free maintenance from the top of the instrument for improved productivity and minimal downtime. The automated shutdown feature switches the system to standby at the end of a sequence to save on electricity and carrier gas. An optional barcode reader records sample ID for reliable traceability. The HS-20 headspace sampler is also compliant with CFR 21 Part 11 through LabSolutions chromatography data system. web: www.shimadzu.com

Software

The iAutomate™ from Thermo Fisher Scientifi c Inc. is a self-serve, freeto-use tool designed to reduce the time associated with confi guring and trialing an automation set-up. Users can quickly and easily build their own system to meet application or process requirements, or modify an existing system around the Orbitor or Orbitor BenchTrak plate movers, a fully customizable plate mover. This allows for lab- or offi ce-based access for automation optimization and effi cient online estimating. When setting up a project, users have complete access to the product catalog through the software, which can be fi ltered, for example, by instrument type. Once chosen, all products will appear on the main screen and can be assembled via drag-and-drop functionality, where they will automatically snap into alignment around the Orbitor BenchTrak. This can be visualized in 2D or 3D, where a scale model can be inspected in detail from any angle. web: www.thermoscientifi c.com/iautomate.

Light scattering detector

Wyatt Technology Corporation will be launching the µDAWN™ at Pittcon 2014. The µDAWN is a multi-angle light scattering (MALS) detector that can be coupled to any UHPLC system in order to determine absolute molecular weights and sizes of polymers, peptides, and proteins or other biopolymers directly, without resorting to column calibration or reference standards. Wyatt Technology’s µDAWN connects to the Optilab® UT-rEX™, the fi rst refractive index detector for UHPLC. Refractive index detection is a critical component of any UHPLC-SEC-MALS system, so the µDAWN plus UT-rEX equals a combination that transfers the many benefi ts of SEC-MALS analysis to the realm of UHPLC. In order to accommodate the narrow peaks produced by UHPLC separation, Wyatt Technology’s µDAWN engineers reduced the conventional light scattering fl ow cell volume from 63 µL to fewer than 10µL. More importantly, a remarkable improvement was achieved in minimizing interdetector mixing; the band broadening between the µDAWN MALS and Optilab UT-rEX detectors was brought to under 7 µL, while the band broadening between the UHPLC’s UV detector and the µDAWN detector is a mere 2 µL. As a consequence of the reduced cell volume and interdetector band broadening, a µDAWN/UT-rEX system can accurately analyze the molar mass and size of UHPLC peaks without loss of resolution. Further expanding the versatility of the µDAWN is the WyattQELS™ Dynamic Light Scattering (DLS) module. This embedded accessory measures DLS in the µDAWN fl ow cell simultaneously with MALS acquisition, computing hydrodynamic radii “on-the-fl y.” And fi nally, the µDAWN user experience is augmented by its colour touchscreen front panel display which shows the chromatographic conditions, instrument diagnostics, and much more. web: www.wyatt.com

Powder Characterization

Freeman Technology will be exhibiting the FT4 Powder Rheometer® at Pittcon 2014, a device that can be used in many industrial sectors, from pharmaceuticals to bulk powders. The system delivers data that support process and product understanding and the optimisation of powder processes. Particular benefi ts are seen in applications where traditional powder testing techniques have limitations. An example of this and a thriving area of interest is additive manufacture (AM) or 3D printing. The FT4 Powder Rheometer measures a range of bulk, shear and dynamic powder properties under conditions that refl ect a diverse range of process environments. With seven standard test methods capable of measuring powders under consolidated, aerated and even fl uidised conditions the FT4 Powder Rheometer allows comprehensive analysis of a number of critical process related powder parameters, such as fl owability. web: www.freemantech.co.uk

new Products

Cytometry System

EMD Millipore launches the guava easyCyte™ 12 fl ow cytometry system. The new platform consumes less sample, generates less waste and is easier to maintain than traditional systems. The guava easyCyte™ 12 fl ow cytometer uses three excitation lasers to provide up to 12 simultaneous detection parameters, including 10 fl uorescent colors plus forward and side scatter for size and granularity determination. Single-sample and multi-sample processing options are offered, and high-throughput analysis is possible with robotic sample trays that automatically handle 96-well micro¬plates and up to 10 sample tubes. It is capable of detecting mammalian and micro¬bial cells and beads, and offers an intuitive interface. A sample of fl uorescently labeled cells is aspirated into a microcapillary fl ow cell, which eliminates the need for sheath fl uid and provides absolute cell counts. In addition, the fl ow cell is self-aligning and user-replaceable, reducing downtime and service visits. web: www.emdmillipore.com/guava.

comPany & advertiser index

COMPANY PAGE WEBSITE

aeterna Zentaris ............................... 6 .............................. www.aezsinc.com bioniche life sciences inc. .................. 6 .............................www.bioniche.com caledon labs ................................... 6 .....................www.caledonlabs.com canadian society for chemical .................................................................... technology ....................................... 4 ...................... www.cheminst.ca/cct cole palmer...................................... 16 ........................ www.colepalmer.com eMd Millipore .................................. 15 ......................www.emdmillipore.com eppendorf ....................................... 20 ......................... www.eppendorf.ca Freeman technology .......................... 15 ....................www.freemantech.co.uk halifax biomedical inc. ........................ 6 .................www.halifaxbiomedical.com helix biopharma corp. ....................... 5 ................... www.helixbiopharma.com mandel ............................................ 5 ...............................www.mandel.ca metrohm canada ............................. 9 ......................www.metrohmca.com Molecular devices ............................ 16 ............... www.moleculardevices.com oven industries ................................ 16 .............................www.ovenind.com Panasonic ....................................... 19 ............www.twinguardseries.com promega corporation ........................ 15 ...........................www.promega.com Qu biologics inc. ................................ 5 .........................www.qubiologics.com shimadzu scientifi c ........................... 15 .......................... www.shimadzu.com sirona biochem corp. ........................ 5 ....................www.sironabiochem.com stem cell therapeutics corp. .............. 6 .....................www.stemcellthera.com thermo scientifi c .............................. 15 ................ www.thermoscientifi c.com vwr ................................................ 2 ................................. www.vwr.com waters corporation .......................... 15 ............................. www.waters.com wyatt technology corporation ........... 15 ............................... www.wyatt.com

Cytometer

Molecular Devices® has released its next-generation SpectraMax® MiniMax™ 300 Imaging Cytometer enabling both cellular visualization and fi rst-of-its-kind stain free cellbased analysis on the fi eld-upgradable SpectraMax® i3 Multi-Mode Microplate Reader. Brightfi eld and fl uorescence based green and red channel cellular image acquisition and analysis is made simple using the SoftMax Pro® software workfl ow. With two additional fl uorescence detection channels researchers may now perform and analyze a wide range of cellular viability and cell toxicity assays, including ratiometric assays such as transfection effi ciency. The SpectraMax i3 system comes with three integrated detection modes and a fl exible design that enables a wide array of assay possibilities. The patented user-exchangeable cartridge design also expands the system’s detection capabilities with cartridges like the recently launched ScanLater™ Western Blot Detection System, which enables protein analysis on a plate reader. The SpectraMax i3 platform with MiniMax 300 Imaging Cytometer and ScanLater Western Blot System are all managed through SoftMax® Pro Data Acquisition and Analysis Software. The SpectraMax i3 System is also available for use in GMP and GLP labs when used with SoftMax® Pro 6 GxP Microplate Data Compliance Software. web: www.moleculardevices.com/spectramax

Peristaltic Pumps

The new Ismatec® ICC 4-Channel 8-Roller Peristaltic Pump from Cole-Parmer is a four-channel peristaltic pump that lets users individually control the fl ow of each channel from the keypad or via computer. Each channel also offers bidirectional fl ow for even more versatility. The micropump delivers continuous pumping or precision dispensing up to 35 mL/min. Independent channel calibration minimizes tube-to-tube differences, resulting in high calibration accuracy. Easy-to-use tubing cassettes enable fast changeovers. The pump contains a USB interface for quick connections. web: www.coleparmer.com

Temperature Controllers

Oven Industries Inc. announces the launch of its new laboratory temperature controllers with ramp/soak capabilities. The 5R6-900 benchtop controller comes contained in an all in one enclosure and can be plugged into the wall as a self-contained temperature control system with its own power supply. The temperature controller can also be used universally, which allows the user to use the device wherever they are located. As a solid state MOSFET bidirectional compact unit featuring an internal power supply, it is also capable of loading currents up to 10A. The compact size, as well as the isolated communication port, makes using the 5R6-900 benchtop temperature controller a breeze. User-friendly and PC programmable, the electronic controller easily connects to a computer through the electrically isolated RS232 communications port. The computer can be utilized as a connector and the unit can stand alone, once the desired parameter settings are in place. These settings are kept in the non-volatile memory. web: www.ovenind.com/