New Products

Protein Characterization

The new Zetasizer Nano ZSP from Malvern Instruments is a high specification dynamic light scattering system that delivers unique protein characterization capabilities in a single, easy to use instrument. This top-of-the-range addition to Malvern’s established Zetasizer Nano family enables highly sensitive measurement of zeta potential, for rapid, reliable measurement of the electrophoretic mobility of proteins, and subsequent calculation of the key parameter of protein charge. The Zetasizer Nano ZSP requires only 20 microliters of sample and measures at concentrations down to one mg/mL. A suite of protein calculators has been added as part of the software developments that accompany the launch of the Zetasizer Nano ZSP, which are included with the instrument as standard. These include a dynamic DLS Debye Plot which allows calculation of the DLS interaction parameter, especially useful in protein formulation for biological therapeutics. There is also the ability to calculate protein charge from protein mobility, F(ka) from the Henry equation, interparticle distance, and thermodynamic diameter (virial radius). Web: www.malvern.com/nano-zsp

Pumps

The Cavro Centris Pump from Tecan is now available with a range of glass syringes and plastic valves to complement the existing portfolio of long-life ceramic components. These new options provide customers with a greater choice of materials to suit their instrument design, bringing the advanced features of the Cavro Centris Pump to a wider range of precision liquid handling applications. The Cavro Centris Pump is a compact, UL-recognized syringe pump module for use in OEM laboratory instruments. Offering exceptional liquid handling characteristics, with flow rates from 5 nl/s up to 5 ml/s, it sets new industry standards for accuracy, reliability and precision. Web: www.tecan.com/cavropumps

Extruder

Thermo Fisher Scientific Inc. launches its Thermo Scientific Pharma 11 parallel co-rotating twin-screw extruder. The 11 mm extruder is designed for pharmaceutical applications including reducing material costs, making the device easier to use and optimizing lab space. The benchtop Pharma 11 uses a minimal amount of sample material (20 g) and features a user-friendly touchscreen with integrated feeder control. For the first time, the Pharma 11 offers a complete strandline, containing air-cooled conveyor belt and adjustable pelletizer, all with the convenient footprint of a standard fumehood. The new extruder features a throughput of 20 g/h to 2.5 kg/h and is easily convertible from hot melt extrusion (HME) to twin screw granulation (TSG) applications. Ideal for a wide variety of drug development applications, including drug delivery systems, implants, tablets and granules. Web: www.thermoscientific.com

Spectrometer

The combined FT-IR spectrometer/rheometer introduced by Thermo Fisher Scientific Inc. provides a powerful analytical workstation for quickly optimizing the pharmaceutical manufacturing process. This Thermo Scientific Rheonaut module enables the Thermo Scientific HAAKE MARS III rheometer to be coupled with either a Thermo Scientific Nicolet iS10 or Nicolet™ iS™50 FT-IR spectrometer to help researchers easily identify and quantify changes in product properties. The Rheonaut module was developed as a piece of analytical equipment by Resultec in Illerkirchberg, Germany, for exclusive resale by Thermo Fisher Scientific. The new spectrometer/rheometer features a rapid multi-technique assessment that is deployed in under 60 seconds for fast-changing samples. The seamless coupling of the instruments enables identical sample and simultaneous test conditions, as well as reliable correlation of results. Web: www.thermoscientific.com

Pipettes

Eppendorf presents its new electronic pipette Eppendorf Xplorer plus®. The intuitive operating concept and ergonomic display of the Xplorer sets new standards in simplicity, precision and reproducibility. The Eppendorf Xplorer is specially designed for users working with complex or long pipetting series requiring the utmost in exact setting of parameters, maximum reproducibility and low operating force. Now with the release of the Xplorer plus there are additional intelligent applications, adjustable fixed-volumes, and individual programming tasks are performed much faster and easier. The Xplorer plus also includes a history function that automatically saves the last parameters for faster handling. A password can be entered to guarantee the highest degree of protection for personal programming and settings. These features mean no more delays due to complicated programming or inflexible processes. Instead, get precisely adjustable parameters, maximum reproducible results, fatigue-free work and consistent, full control over the pipetting processes. Web: www.eppendorf.com/xplorer

Mills

Retsch Cyclone Mills are ideally suited for temperaturesensitive samples and the grinding of solids depending on the material properties. The rotation of the mill’s rotor or a connected vacuum cleaner produces a rotating air flow inside the cyclone, thus optimizing the air throughput. As a result, sample and grinding tools are cooled and material discharge is improved. These effects are particularly beneficial when grinding temperature-sensitive materials. Further advantages are the complete recovery of the sample material as well as the possibility to process larger sample volumes. Retsch line of laboratory mills includes various models which can be equipped with a cyclone. Whereas the rotor mill TWISTER has an integrated cyclone, the Ultra Centrifugal Mill ZM 200 can be optionally equipped with a cyclone and collecting vessels of various sizes. Web: www.retsch.com

NEW PRODUCTS

V3 Western Workflow

Streamline your western blotting protocol with the new V3 Western Workflow from BioRad. The V3 Western Workflow combines traditional techniques with the latest advances in protein electrophoresis, transfer, and imaging. The complete V3 workflow incorporates traditional blotting techniques with innovative tools, such as TGX Stain-Free™ precast gels, the Trans-Blot® Turbo™ system, and the ChemiDoc™ MP imager, to quickly check electrophoresis results and blot transfer quality prior to western blotting, simplifying total protein quantitation analysis post-immunodetection to obtain results faster. Visual checkpoints enabled by stain-free technology are built into each step to ensure confidence in the quality of your results and a simplified total protein normalization method provides more accurate quantitative results. The V3 Western Workflow offers high quality separation of proteins in as little as 15 minutes and protein transfer in as little as three minutes. Web: www.bio-rad.com

Benchtop meter

Mettler Toledo introduces its SevenExcellence™ benchtop meter for measurements of pH, conductivity, ion concentration or ORP (oxidation reduction potential). SevenExcellence is a modular instrument that measures one, two or three channels in parallel. Operation is intuitive thanks to its unique seven-inch touch screen and its ingenious guided interface. These new meters fulfill requirements in multiple industries in a wide range of workplaces. Its flexible methods effectively manage complex applications and the stringent requirements of regulated markets. SevenExcellence also provides efficiency in routine lab work thanks to its high degree of automation and sophisticated connectivity, and is available in various convenient and ready-to-use kits, most of them adapted to certain industries’ needs. Web: www.mt.com

Vacuum pumps

Edwards’ introduces its nEXT turbomolecular vacuum pumps. Equipped with a state of the art rotor design, nEXT is meant for applications such as high energy physics and particle accelerators in a compact size. Designed with minimum maintenance requirement and maximum reliability and user serviceability in mind, the complete nEXT bearing mechanism can be serviced quickly and simply in the field thereby significantly reducing the overall cost of ownership. Despite very low power requirements, nEXT achieves standard nitrogen pumping speeds for its size - at up to 400 litres per second. Web: www.edwardsvacuum.com/next

Chromatography system

Metrohm’s new Combustion Ion Chromatograph (CIC) automates the determination of halogens and sulfur in fuels, lubricants, additives, other petroleum products, polymers, flame retardants, textiles, special chemicals, catalysts and waste. CIC complies with environmental requirements, including DIN, EN, IEC, RoHS, WEEE and more. The flame sensor technology measures the intensity of light from the pyrolysis oven during combustion, controls the feed rate of the sample boat and prevents soot formation. Different matrices & sample quantities are automatically combusted by one universal method - prior knowledge about the sample is unnecessary. This method surpasses offline digestion by providing better sample throughput, accuracy and precision. The system’s unique 2-in-1 autosampler can run both solid and liquid samples by simply changing the sample head. www.metrohmna.com

COMPANY & ADVERTISER INDEX

COMPANY PAGE WEBSITE

Aeterna Zentaris Inc. ........................ 7..................www.aeternazentaris.com Baxter International Inc...................... 2.................................. www.baxter.ca BC Cancer Agency ............................. 6.......................... www.bccancer.bc.ca Boehringer Ingelheim.......................... 7............. www.boehringer-ingelheim.ca Caledon Laboratory Chemicals ......... 5.....................www.caledonlabs.com Canadian Society for................................................................................... Chemical Technology........................ 4....................www.chem-tech.ca/cct Dalton Pharma Services..................... 3................................www.dalton.com Edwards .......................................... 16................ www.edwardsvacuum.com Eppendorf.................................... 15, 20................... www.eppendorf.com Genome Canada................................. 6...................... www.genomecanada.ca Immunovaccine Inc............................. 7...........................www.imvaccine.com Malvern Instruments ........................ 15............................ www.malvern.com Medicago Inc..................................... 7........................... www.medicago.com Medicure Inc..................................... 7........................... www.medicure.com Methanex Corp. ................................ 6...........................www.methanex.com Metrohm ..................................... 11, 16................www.metrohmusa.com Mettler Toledo.................................. 16....................................www.mt.com Miele Professional........................... 7.............. www.mieleprofessional.ca Millipore ........................................ 19........................ www.millipore.com Oncolytics Biotech Inc........................ 6................www.oncolyticsbiotech.com Patheon Inc....................................... 6.............................www.patheon.com PharmaNet/i3.................................... 6..................... www.pharmanet-i3.com Qu Biologics ...................................... 6.........................www.qubiologics.com Resverlogix Corp................................ 7.........................www.resverlogix.com Retsch ............................................ 15.............................. www.retsch.com Tecan............................................... 15............................... www.tecan.com Thermo Fisher Scientific Inc............... 15................ www.thermoscientific.com VWR ................................................ 2................................. www.vwr.com Wyvern Scientific ........................... 13..............................www.mandel.ca