School of Pharmacy & Life Sciences Research Portfolios
260117- 025
2017/2018
www.rgu.ac.uk/pals
Staff Listed
WELCOME ”
The School of Pharmacy and Life Sciences is the largest school in Robert Gordon University (RGU) comprising over 50 academic staff. In 2013, the School moved to modern, purpose-build accommodation equipped with world-class laboratory and support facilities. The School currently delivers undergraduate courses in Biomedical Sciences, Dietetics, Forensic and Analytical Science, Nutrition, and Pharmacy along with postgraduate MSc courses in Clinical Pharmacy Practice and Instrumental Analytical Sciences. The School also has a thriving postgraduate research programme. There are currently more than 40 doctoral students undertaking research in the School and research degrees are offered leading to the awards of Master of Research, Doctor of Philosophy and the Doctorate of Professional Practice. To complement this portfolio of taught courses and postgraduate teaching, staff in the School conduct high-impact research
under two main themes; Translational Research and Clinical Practice Research. Key areas within these themes include Analytical, Biological and Pharmaceutical Sciences, Dietetics and Pharmaceutical Care. External grant income in excess of £3M has been secured for session 2016-17 from a variety of sources including Research Councils, Scottish Government, Pharma industry and medical charities. Collaborative projects, including consultancies, are underway with Universities and Research Centres in the Middle East, Europe and the United States. Thank you for enquiring about research in the School of Pharmacy and Life Sciences at RGU. This introduction and welcome can only provide a brief overview of some of the research that is undertaken in the School. Please contact me, or any of the staff listed in this guide, to discuss your research interests.
”
Prof Donald Cairns Head of School, PALS.
TRANSLATIONAL RESEARCH Theme lead Prof. Susan J. Duthie Dr. Gemma Barron Prof. Donald Cairns Dr. Stuart Cruickshank Dr. Alberto Di Salvo Dr. Christine Edwards Dr. Carlos Fernandez Dr. Marie Goua Dr. Graeme Kay Dr. Rachel M. Knott Dr. Colin Thompson Prof. Paul Kong Thoo Lin Prof. Linda A. Lawton Dr. Lindsey Masson Dr. Kerr H. Matthews Dr. Barbara McKenzie Prof. Wolfram Meier-Augenstein Dr. Simon Officer Dr. Iain Rowe Dr. Kyari Yates PRACTICE RESEARCH Theme lead Prof. Derek Stewart Dr. Scott Cunningham Prof. Lesley Diack Dr. Katie MacLure Dr. Myra Mackensie-Fraser Dr. Noelle O’Driscoll Dr. Alison Strath Dr. Antonella Tonna Page 1
TransLATIONAL RESEARCH
Optimum health & wellbeing • diet & health • natural products • vascular health; • clinical dietetics • public health policy) Drug discovery, novel antimicrobial technologies and nanomaterials • natural products • drug & novel matrices design Environmental monitoring • sensors • clean technology • bioactive natural products & algal biotechnology
Prof. Susan J. Duthie
Transitional REsearch THEME LEADER
s.j.duthie@rgu.ac.uk
Professor and Associate Head of School (PALS)
Telephone
ResearchGate https://www.researchgate.net/profile/Susan_Duthie Orcid Link http://orcid.org/0000-0002-7990-4437 RGU Link http://www.rgu.ac.uk/dmstaff/duthie-susan Professor Duthie leads translational research
models and in human case-control and intervention
within PALS. Her expertise centers around how
studies. Moreover, she has investigated how gene-
diet affects human health and particularly how
nutrient interactions influence risk of malignancy,
nutrition influence cell function and genomic
specifically how polymorphisms in key folate
stability. She has determined mechanistically
metabolising enzymes influence genomic stability
how specific phytochemicals (including
and incidence of colorectal cancer in humans and
flavonoids, antioxidant vitamins and folic acid)
has demonstrated how intervention with folic acid
influence DNA damage and DNA repair.
decreases DNA damage in healthy volunteers. With regards to CVD, she has shown how folate status
Recently, Prof. Duthie’s work has centred on how B vitamins influence human health and disease. She has established how folate status influences genomic stability, global protein expression (proteomics) and genome-wide DNA methylation in vitro, in rodent
alters protein expression and DNA methylation status in human aorta smooth muscle cells and that longterm B vitamin deficiency increases atherosclerosis by perturbing vascular lipid metabolism in transgenic ApoE mice.
1. Increasing fruit and vegetable intake by dietary intervention: impact on nutritional biomarkers and attitudes to dietary change. Duthie SJ, Duthie GG, Russell WR, Kyle JAM, Macdiarmid, J, Rungapamestra, V, Stephen, S, Megias-Baeza C , Kaniewska JJ, Shaw, L, Milne L, Bremner D, Ross K, Morrice P , Pirie LP, Horgan G and Bestwick CS. Brit. J. Nutr., (under review). 2. B vitamin deficiency alters the expression of key proteins that regulate vascular smooth muscle cell proliferation and migration in the aorta of atherosclerotic mice. Duthie SJ, Beattie JH, Gordon M-J, Pirie LP, Reid MD, Duncan GJ, Horgan G and McNeil CJ. Genes & Nutrition (2015), 10 (1): 446-457. 3. Transcriptome analysis of peripheral blood mononuclear cells in human subjects following a 36 hour fast provides evidence of subtle effects on genes regulating inflammation and apoptosis as well as energy metabolism. Elliot RM, de Roos B, Duthie SJ, Boiwman FG, Rubio-Aliaga I, Crosley LK, Mayer C, Horgan G, Polley AC, Heim C, Coort SL, Evelo CT, Mulholland F, Daniel H, Mariman EC and Johnson T. Genes & Nutrition (2014), 9; 432-443.
+44 (0) 1224 262815 Research Interests •Mechanisms • of action of dietary nutrients on human health and disease •Impact • of plant compounds including phytophenols, flavonoids and anthocyanins on human health; cancer and vascular disease •Effect • of micronutrients on cancer risk; differential effects of diet and supplements on malignant transformation •Impact • of B vitamins and antioxidants on cognitive function and dementia in the elderly •Impact • of natural products from underused ethnic foods on human health Page 3
Dr. Gemma Barron
BSc (Hons), PhD, MRSC, MRSB
g.barron@rgu.ac.uk
Lecturer in Biomedical Sciences, Researcher (CORE).
Telephone
ResearchGate https://www.researchgate.net/profile/Gemma_Barron Orcid Link http://orcid.org/0000-0003-2217-0900 RGU Link http://www.rgu.ac.uk/dmstaff/barron-gemma
+44 (0) 1224 263154
Dr Barron’s qualifications include a PhD in
vitro (skin, brain, bladder and oesophageal cancer
Medicinal Biochemistry (2010) and First Class
cell lines).
BSc Honours degree in Forensic Science (2006) both from Robert Gordon University, Aberdeen.
Gemma joined Robert Gordon University (2013-present) as a Research Fellow in the Institute of
Research Interests •Angiogenesis • at the cellular/ molecular level
Health and Wellbeing Research. In September 2015, She moved to the University of Dundee (2010-2013)
she joined the School of Pharmacy and Life Sciences
to undertake post doctoral research on a FP7-SME
as a Part-Time Lecturer and Part-Time Research
funded project investigating the early detection of
Fellow within the Centre for Obesity Research and
cancer using photonic crystals lasers (EDOCAL) in
Education (CORE).
1. Kopsida M, Barron GA, Bermano G, Goua M, Kong Thoo Lin P. Novel bisnaphthalimidopropyl (BNIPs) derivatives as anticancer compounds targeting DNA in human breast cancer cells Organic & Biomolecular Chemistry, Org. Biomol. Chem., 2016,14, 9780-9789 DOI: 10.1039/C6OB01850E
•Cancer • therapeutics: DNA damage and repair •Cancer • diagnostics: Biomarkers in disease •Effect • of natural products in cancer
2. Barron GA, Goua M, Kuraoka I, Bermano G, Iwai S, Kong Thoo Lin P. Bisnaphthalimidopropyl diaminodicyclohexylmethane induces DNA damage and repair instability in triple negative breast cancer cells via p21 expression. Chemico-Biological Interactions, 2015;242:307-315. DOI:10.1016/j.cbi.2015.10.017 3. Barron GA, Bordet E, Goua M, Bermano G. Modulation of angiogenesis by inflammatory markers and the role of matrix metalloproteinases in an endothelial cell/fibroblast co-culture system. Current Angiogenesis, 2014;3(3):152-163. DOI: 10.2174/22115528 03666141113211829 4. Barron GA, Valentine R, Moseley H, Brancaleon L, Hill C, Woods JA. Porphyrin profile in four human cell lines after supplementation with 5-aminolaevulinic acid and its methyl ester. Photodiagnosis and Photodynamic Therapy, 2013;10:654-663. DOI: 10.1016/j.pdpdt.2013.08.004 5 Barron GA, Moseley H and Woods JA. Differential sensitivity in cell lines to photodynamic therapy in combination with ABCG2 inhibition. Photochemistry and Photobiology B: Biology 2013;126:87-96. doi: 10.1016/j.jphotobiol.2013.07.003
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Prof. Donald Cairns
BSc (Hons), PhD, FRPharmS, C.Sci, C.Chem, FRSC.
d.cairns@rgu.ac.uk
Professor and Head of School (PALS).
Telephone
ResearchGate https://www.researchgate.net/profile/Donald_Cairns Orcid Link http://orcid.org/0000-0001-7086-7441 RGU Link http://www.rgu.ac.uk/dmstaff/cairns-donald
+44 (0) 1224 262501
Professor Cairns leads the strategic planning,
year spent in hospital pharmacy, returned to
coordination, development and supervision
Strathclyde to undertake a PhD on the synthesis and
of academic work at the School of Pharmacy
properties of benzylimidazolines.
and Life Sciences. He is a member of the GPhC, the Royal Pharmaceutical Society, the Association of Pharmaceutical Scientists and in 2008 was made a Fellow of the Royal Society of Chemistry. He has served as a member of the British Pharmacopoeia Commission and an Expert Advisory Group of the Commission on Human Medicines. In 2015 he was made a Fellow of the Royal Pharmaceutical Society.
Following a year as a post-doctoral research fellow, Dr Cairns moved to Leicester Polytechnic (now De Montfort University) where he held a five-year lectureship in pharmacy. In 1992 he was appointed senior lecturer in medicinal chemistry in Sunderland School of Pharmacy and in 2003 moved to a post of Associate Head of the School of Pharmacy at The Robert Gordon University in Aberdeen. In 2006,
Research Interests •The • design, synthesis and evaluation of novel prodrugs for the treatment of nephropathic cystinosis •The • design, synthesis and evaluation of selective anticancer agents targeted to high-order forms of DNA
he was promoted to Professor of Pharmaceutical Dr Cairns graduated in pharmacy from the University
and Medicinal Chemistry at RGU and in 2012 was
of Strathclyde in 1980 and after a pre-registration
appointed Head within the School.
•The • molecular modelling of drug / DNA interactions
1. McKenzie, Kay, Matthews, Knott and Cairns ‘The hen’s egg chorioallantoic membrane (HET-CAM) test to predict the ophthalmic irritation potential of a cysteamine-containing gel: Quantification using Photoshop® and ImageJ.’ International Journal of Pharmaceutics 490, 2015, pp. 1-8 DOI information: 10.1016/j.ijpharm.2015.05.023 2. Benylles, Cairns, Cox and Kay ‘Three salts from the Reaction of Cysteamine and Cystamine with l (+) Tartaric Acid’ Acta Crystallographica Section C, 2013, C69, 658-664, doi: 10.1107/S0108270113012377 3. Buchan, Kay, Matthews and Cairns, ‘Suppository formulations as a potential treatment for Nephropathic Cystinosis’ J. Pharm. Sci, 2012, DOI 10.1002/jps.23246 4. Chahrour, Cairns and Omran “Small molecule Kinase Inhibitors as Anti-Cancer Therapeutics”, Mini Rev. Med. Chem. 2012, 12 (5), 399-411
Page 5
Dr. Stuart Cruickshank BSc PhD
s.f.cruickshank@rgu.ac.uk Telephone
Lecturer in Pharmacology Orcid Link http://orcid.org/0000-0003-2146RGU Link http://www.rgu.ac.uk/dmstaff/cruickshank-stuart
Dr Cruickshank has research skills in the areas
gives insight as to how environmental factors are likely
of whole-cell patch clamp and extracellular
to impact vascular function. Long term integration of
electrophysiology, epifluorescent microscopy,
hydrostatic pressures affect neuronal function and
small vessel wire myography, time series
the use of a model invertebrate system has provided
analysis (including MESA and autocorrelation).
insight as to how, over extended periods, sensory
+44 (0) 1224 262535
Research Interests •Vascular • smooth muscle physiology
feedback modulates interneuron activity. His research interests are varied but include understanding how environmental cues, for example
Dr Cruickshank graduated with a PhD from University
pressure, affect physiological function. The partial
of Aberdeen followed by post-doctoral position at
pressure of oxygen affects vascular smooth muscle,
University of Strathclyde. For the last 13 years he has
and understanding how such stimulus is transduced
been employed as a lecturer in RGU.
•Pulmonary • vein physiology •[Ca2+]i • regulation •Ion • channel function •Invertebrate • neurophysiology
1. Dopinescu C, Widmer H, Rowe I, Wainwright C, Cruickshank SF (2012). Hypoxia sensitivity of a voltage-gated potassium current in porcine intrapulmonary vein smooth muscle cells. Am. J.Physiol. (Lung Cell.Mol.Physiol.) 303(5):L476-86.doi:10.1152/ ajplung.00157.2012 2. Sunil Jit RJ Logantha, Stuart F Cruickshank, Edward G Rowan, Robert M Drummond (2010) Spontaneous and electrically evoked Ca2+ transients in cardiomyocytes of the rat pulmonary vein. Cell Calcium, 48(2-3):150-60. doi: 10.1016/j. ceca.2010.08.002 3. Yildiz I, Deniz E, McCaughan B, Cruickshank SF, Callan JF, Raymo FM. (2010) Hydrophilic CdSe-ZnS core-shell quantum dots with Reactive Functional Groups on Their Surface. Langmuir 26(13):11503-11 doi: 10.1021/la1010488 4. Yildiz I, McCaughan B, Cruickshank SF, Callan JF, Raymo FM. (2009) Biocompatible CdSe-ZnS core-shell quantum dots coated with hydrophilic polythiols. Langmuir 16;25 (12):7090-6 doi: 10.1021/la900148m. 5. .Fraser PJ, Cruickshank SF, Shelmerdine RL, Smith LE, (2008). Hydrostatic Pressure Receptors and Depth Usage in Crusta-
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Dr. Alberto Di Salvo BSc (Hons) PhD MRSC
+44 (0) 1224 262581
Orcid Link http://orcid.org/0000-0003-2091-6473 RGU Link http://www.rgu.ac.uk/albertodisalvo
Dr Di Salvo’s research interests lie in the area
followed by a PhD in Medicinal Chemistry Design
of selective toxicity and anticancer agents.
and synthesis of tumour activated oligopeptide
His key research skills include multistep
prodrugs that exploit the proteolytic activity of MMP-
synthesis, asymmetrisation (enzymatic and
98168 .
non-enzymatic), preparative chromatography spectrometry.
Dr Di Salvo also worked at the Rega Institute for Medical Research, Belgium and the City College of New York, before joining the School of Pharmacy and
Dr Di Salvo attended Edinburgh Napier University
a.di-salvo@rgu.ac.uk Telephone
Lecturer in Pharmaceutical Sciences
and structure elucidation by NMR and mass
Life Sciences in Aberdeen..
Research Interests •Medicinal • chemistry •Organic • spectroscopy •Structural • elucidation with 2D NMR
and completed a BSc (Hons) in Applied Chemistry
1. Di Salvo, A; Dugois, P; Tandeo, D; Peltekian, M; Lin, PKT; Synthesis, cytotoxicity and DNA binding of oxoazabenzo[de]anthracenes derivatives in colon cancer Caco-2 cells; EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 69, 754-761. 2. Omran, Z; Kay, G; Di Salvo, A; Knott, RM; Cairns, D; PEGylated derivatives of cystamine as enhanced treatments for nephropathic cystinosis; BIOORGANIC & & MEDICINAL CHEMISTRY LETTERS; 2011, 21 (1), 45-47. 3. Liu, F., Di Salvo, A., Herdewijn, P. 2008, Synthesis of 2818c-Cyclohexenylnucleosides and Corresponding CeNA Building Blocks, Current Protocols in Nucleic Acid Chemistry, June 2008, Volume 1, Unit 1.20. 4. Dias, N., Goossens, J-F., Baldeyrou, B., Lansiaux, A., Colson, P., Di Salvo, A., Bernal, J., Turnbull, A., Mincher, D.J., and Bailly, C. 2005, 8165Oxoazabenzo[de]anthracenes conjugated to amino acids: synthesis and evaluation as DNA-binding antitumour agents8166, Bioconjugate Chemistry, 16, 949-958. 5. Van Valckenborgh, E., Mincher, D.J., Di Salvo, A., Van Riet, I., Young, L., Van Camp, B., and Vanderkerken, K. 2005, 8165Targeting an MMP-9-activated prodrug to multiple myeloma diseased bone marrow: a proof of principle in the 5T33MM mouse model8166, Leukemia, 19, 1628-1633
Page 7
Dr. Christine Edwards
BSc, PHd
c.edwards@rgu.ac.uk
Researcher and lecturer in microbial biotechnology,
Telephone
ResearchGate https://www.researchgate.net/profile/Christine_Edwards6 Orcid Link http://orcid.org/0000-0001-5180-9043 RGU Link http://www.rgu.ac.uk/dmstaff/edwards-christine
Dr Edwards developed her interest in bioactive
In 1994, Dr Edwards joined Biotage as a technical
natural products, in particular toxins produced
support specialist for purification products from R & D
by cyanobacteria, whilst engaging in her
to production scale. This involved collaboration with
postdoctoral research at the University of
customers on method development and optimisation,
Dundee.
and resulted in several publications.
Her current research group has facilities for
In 2005, she joined the School of Pharmacy and Life
cyanobacterial culture, chemical analysis (high
Sciences to resume a more active role in research,
performance liquid chromatography with photodiode
with emphasis on cyanobacterial toxins, and their
array, fluorescence, mass, evaporative light scattering
occurrence and fate in the environment. She has many
detection), bioassay, and chromatography purification
years experience on the production of high quality
suite.
bioactive compounds for research tools.
+44 (0) 1224 262839
Research Interests •Production • of Bioactive compounds •Exploitation • of whisky waste for high values compounds •Analysis • and removal of cyanotoxins (water/shellfish) •Microbial • biotechnology
1. Delgado-Baquerizo, M, Giaramida, L., Reich, P.B., Khachane, A.N., Hamonts, K., Edwards, C., Lawton, L.A., Singh, B.K. (2016) Lack of functional redundancy in the relationship between microbial diversity and ecosystem functioning. Journal of Ecology (accepted for publication). 2. Photos-Jones, E., Edwards, C., Haener, F., Keane, C., Lawton, L.A., Leanord, A., Perdikatsis, V. (2016) Archaeological Medicinal Earths as Antibacterial Agents: the case of the Basel Lemnian sphragides. Geology and Medicine: Historical Connections (accepted for publication). 3. Faassen, E.J., Antoniou,M.G., Beekman-Lukassen, W., Blahova, L., Chernova, E., Christophoridis, C., Combes, A., Edwards, C., Fastner, J., Harmsen, J., Hiskia, A., Ilag, L.L., Kaloudis, T., Lopicic, S., Lürling, M., Mazur-Marzec , H., Meriluoto, J., Porojan, C., Viner-Mozzini, Y Zguna, N. (2016) A Collaborative Evaluation of LC-MS/MS Based Methods for BMAA Analysis: Soluble Bound BMAA Found To Be an Important Fraction. Marine Drugs (accepted for publication). 4. Pestana, C. J., Edwards, C., Prabhu R., Robertson, P.K.J., Lawton, L.A.. (2015) Photocatalytic degradation of eleven microcystin variants and nodularin by TiO2coated glass microspheres. Journal of Hazardous Materials 300, 347–353.
Page 8
Dr. Carlos Fernandez MChem PhD CChem CSci MRSC MInstP MECS Orcid Link http://orcid.org/0000-0001-6588-9590 RGU Link http://www.rgu.ac.uk/dmstaff/fernandez-carlos
Dr Fernandez gained his MChem at the
Reactions”. In 2010 he took a role as a Senior
University of Almeria (Spain) in 2002 and
Scientist at Oxtox Ltd. (Manchester) working on
then moved to the UK where he undertook a
the development of an Electrochemical Sensor
research year at the University of Durham in
using Screen-Printed Electrodes to detect
2003 investigating Ruthenium complexes using
methamphetamine, ampthetamine, cocaine and
X-Ray diffraction.
ecstasy in oral fluid for the purpose of roadside testing. In 2013 he took a position at RGU in The
Hull where he took a four year position as a GTA (Graduate Teaching Assistant) along with a PhD. He obtained his PhD in 2009 on “Electrocatalytic
c.fernandez@rgu.ac.uk Telephone
Lecturer in Analytical Chemistry
In 2005 Dr Fernandez moved to the University of
+44 (0) 1224 262559
Research Interests •Liquid-Liquid • interface & Electrochemistry at the Three Phase Boundary (droplets) & Electrochemiluminescence
School of Engineering as a Research Fellow/Business Development Officer. In 2014 he was appointed as
•Bioelectrochemistry •
a Lecturer in Analytical Chemistry at the School of Pharmacy & Life Sciences.
•Forensic • Electrochemistry •Graphene • Electrochemistry
1. Fernandez, T. Ravishankar, K. Sureshkumar, S. Teixeira and T. Ramakrishnappa. Electroanalysis, 2016, 28, 3, 452-461: Ag Doped Titanium Dioxide Nanocomposite-Modified Glassy Carbon Electrode as Electrochemical Interface for Catechol Sensing 2. Fernandez, M. M. Sundaram, A. Biswal, D. Mitchell and R. Jones: Physical Chemistry Chemical Physics (PCCP), 2016, 18, 4711 – 4720: Correlation Among Physical and Electrochemical Behaviour of Nanostructured Electrolytic Manganese Dioxide from Leach Liquor and Synthetic for Aqueous Asymmetric Capacitor 3. Fernandez, L. Cruickshank, S. Officer, P. Pollard, R. Prabhu and M. Stutter. Analytical Sciences, 2015, 31,623-627:Rare Elements Electrochemistry: The Development of a Novel Electrochemical Sensor for the Rapid Detection of Europium in Environmental Samples Using Gold Electrode Modifying with 2-Pyridinol-1-Oxide 4. Fernandez, S. Kruanetr and P. Pollard. Journal of The Electrochemical Society, 2014, 161, (1), H36-H40: Electroanalytical Sensing of Ketamine Using Electrogenerated Chemiluminescence
•Development • sensors for Environmental Applications •Nanocomposites • & Energy Storage Devices (Capacitors)
5. Fernandez, J. Smith, J. Metters, D. Kampouris, O.Sutcliffe and C. Banks. Analyst, 2013, 138, 6185-6191: Forensic Electrochemistry: The Electroanalytical Sensing of Rohypnol® (Flunitrazepam) using Screen Printed Graphite Electrodes without
Page 9
Dr. Marie Goua
BSc(Hons), PhD, CBiol, MRSB, FHEA
m.goua@rgu.ac.uk
Lecturer in Biosciences
Telephone
ResearchGate https://www.researchgate.net/profile/Marie_Goua Orcid Link http://orcid.org/0000-0003-1609-4366 RGU Link http://www.rgu.ac.uk/mariegoua
+44 (0) 1224 262898
Dr Goua’s key research interests include
PhD studies she has been interested in assessing
nutrient gene interaction, cardiovascular
the effects of various fatty acids on inflammatory
disease and cancer in relation to inflammation.
mechanisms such as cytokine expression in prostate
Her skills lie in the areas of cell culture, RNA
and breast cancer cells.
studies, DNA damage, protein studies and flow cytometry.
In line with the research on breast cancer prevention, she is interested in understanding the molecular
Dr Goua carried out her PhD at the Rowett
mechanisms involved in the disease by studying the
Research Institute where she studied the effects of
inflammatory and oxidative pathways in relation to
polyunsaturated fatty acids on adhesion molecules
new anti-cancer compounds and, more importantly,
in relation to atherosclerosis. Since finishing her
natural products.
1. Barron GA, Goua M, Kuraoka I, Bermano G, Iwai S, Kong Thoo Lin P-Bisnaphthalimidopropyl diaminodicyclohexylmethane induces DNA damage and repair instability in triple negative breast cancer cells via p21 expression. Chemico-biological interactions (2015) 242:307-315. 2. Kapravelou G , Martínez R, Andrade AM, Nebot E, Camiletti D, Aparicio V, López-Jurado M, Aranda P, Arrebola 2 F, Fernández-Segura E, Bermano G, Goua M, Galisteo M, and Porres JM- Aerobic interval exercise improves parameters of Non Alcoholic Fatty Liver Disease (NAFLD) and other alterations of metabolic syndrome in obese Zucker rats. Applied Physiology, Nutrition and Metabolism, (2015), 40(12): 1242-1252.
Research Interests •Effects • of nutrients in diseases •Angiogenesis • at the cellular/ molecular level •Inflammation • and DNA damage •Natural • compounds and their effects in cancer, cardiovascular and neurodegenerative diseases •The • effect of different fatty acids on cardiovascular markers
3. Barron GA, Bordet E, Goua M, Bermano G. Modulation of Angiogenesis by Inflammatory Markers and the Role of Matrix Metalloproteinases in an Endothelial Cell/Fibroblast Co-Culture System. Current Angiogenesis (2014) 3(3):152-163. 4. Bermano G, Smyth E, Goua M, Heys S, Wahle K. Impaired expression of glutathione peroxidase-4 gene in peripheral blood mononuclear cells as a biomarker of increased breast cancer risk. Cancer Biomarkers (2010) 7:39-46. 5. Goua M, Mulgrew S, Frank J, Rees D, Sneddon AA and Wahle KWJ. Regulation of adhesion molecule expression in human vascular endothelial and smooth muscle cells by omega-3 fatty acids and conjugated linoleic acids (CLAs): involvement of the transcription factor NF-kB? Prostaglandins, Leukotrienes and Essential Fatty Acids (2008), 78(1):33-43.
Page 10
Dr. Graeme Kay
FRSC, MAPS, SRPharmS, MCSFS
g.kay@rgu.ac.uk
Teaching Group Leader – Chemical Sciences
Telephone
ResearchGate https://www.researchgate.net/profile/Graeme_Kay Orcid Link http://orcid.org/0000-0003-4792-1598 RGU Link http://www.rgu.ac.uk/dmstaff/graeme-kay
+44 (0) 1224 262548
Dr Kay’s research projects have been
that he was employed at Edinburgh Napier University
in the area of medicinal, organic and
as a researcher in organo-medicinal chemistry. He
pharmaceutical chemistry. His key research
was educated at Edinburgh Napier University where
skills include organo-medicinal chemistry,
he gained a BSc (Hons) degree in Applied Chemistry
mass spectrometry, NMR and IR spectroscopy.
and a PhD in Anti-Cancer Medicinal Chemistry.
Specialist research facilities available to Dr Kay include the medicinal chemistry research laboratory and the NMR facility.
Research Interests •Design, • synthesis and bioevaluation of amino-substituted anthraquinones as potential anticancer agents
Dr Kay has received over £230,000 in funded research. Awards include:SPARKS, The Children’s Medical Research Charity and The Cystinosis
Dr Kay joined the University in 2005 after a brief spell
Foundation UK, and the Cystinosis Foundation of
in industry as a development chemist. Previous to
Ireland.
•Design, • synthesis and evaluation of novel pro-drugs for the treatment of Cystinosis •Design, • synthesis of non-invasive imaging agents in Atherosclerosis
1. B. McKenzie, G. Kay, K. H. Matthews, R. M. Knott and D. Cairns. The hen’s egg chorioallantoic membrane (HET-CAM) test to predict the ophthalmic irritation potential of a cysteamine-containing gel: Quantification using Photoshop® and ImageJ. International Journal of Pharmaceutics 490 (2015) 1–8. http://dx.doi.org/10.1016/j.ijpharm.2015.05.023 2. A. Benylles, D. Cairns, P. J. Cox and G. Kay. Three salts from the reactions of cysteamine and cystamine with L-(+)-tartaric acid. Acta Crystallographica Section C, Crystal Structure Communications. Volume 69, Part 6 (June 2013). DOI: 10.1107/ S0108270113012377
•Formulation • of cysteamine as a dosage form for ophthalmic delivery in Cystinosis
3. B. E. Buchan, G. Kay, K. H. Matthews and D. Cairns. Suppository formulations as a potential treatment for Nephropathic Cystinosis. Journal of Pharmaceutical Sciences, Volume 101, Issue 10, pages 3729–3738, October 2012. DOI: 10.1002/jps.23246 4. Omran, Z.; Kay, G.; Moloney, K. A.; Benylles. A.; Knott, R. M.; Cairns, D. Bioorganic & Medicinal Chemistry. Synthesis and in vitro evaluation of novel pro-drugs for the treatment of nephropathic cystinosis. 2011, doi:10.1016/j.bmc.2011.04.022 5. Omran, Z.; Kay, G.; Hector, E. E, Knott, R. M.; Cairns, D. Bioorganic & Medicinal Chemistry Letters. Folate pro-drug of cys-
Page 11
Dr. Rachel M. Knott
BSc, MSc, PhD
r.knott@rgu.ac.uk
Reader, Molecular and Cell Biology
Telephone
ResearchGate https://www.researchgate.net/profile/Rachel_Knott Orcid Link http://orcid.org/0000-0002-4363-8974 RGU Link http://www.rgu.ac.uk/rachelknott
Dr Knott’s work is currently focused on
on the editorial panel of the Gavin Journal of Diabetes
the investigation of the mechanism(s) of
and is a member of the organising committee for the
endothelial cell changes in response to glucose
13 th Global Diabetes Conference and Medical Expo
concentration, pressure and oxygen tension
in Birmingham in 2016 . She has supervised research
in order to develop early interventions for
students and continues to be active in research skill
the prevention of diabetic retinopathy which
development recognising this to be an important
is a severe and debilitating complication of
element for the realisation of future research leaders.
diabetes. Dr Knot graduated from Aberdeen University with Her work has taken her to many international and
a PhD in 1988. Prior to taking up employment at
national conferences and she has authored over 50
Robert Gordon University in 1999 she worked at
research papers, reviews and chapters in books. She
the Rowett Research Institute and the University of
is a reviewer for a number of different journals and is
Aberdeen.
1. Ibie, C. O., Thompson, C. J., Knott R. (2015) In-vitro evaluation of the effect of polymer structure on uptake of novel polymer-insulin polyelectrolyte complexes by human epithelial cells International Journal of Pharmaceutics 12/2014; 479(1). DOI: 10.1016/j. ijpharm.2014.12.058 C. 2. Ibie, O., Thompson, C. J., Knott R. (2015) Synthesis, characterisation and in vitro evaluation of novel thiolated derivatives of polyallylamine and quaternised polyallylamine Colloid and Polymer Science; DOI:10.1007/s00396-015-3561-4 3. Gadad, P. C., Matthews, K. H., & & Knott, R. M. (2013). Silymarin released from sterile wafers restores glucose impaired endothelial cell migration. International Journal of Pharmaceutics, 457 (1), 40-49. 4. Gadad, P. C., Matthews, K. H., & & Knott, R. M. (2013). Role of HIF1alpha and PKC beta in mediating the effect of oxygen and glucose in a novel wound assay. Microvascular Research, 88 , 61-9.
+44 (0) 1224 262524 Research Interests •Ex • vivo explants as model systems for the study of the vascular complication of diabetes •Molecular • mechanisms of vascular change in endothelial cell response due to high and/ or fluctuating concentrations of glucose and oxygen •Non-alcoholic • fatty liver disease: role of vascular change in the onset and progression of hepatic damage •Use • of bioinformatics to inform gene function and disease association in the search for biomarkers of disease and pharmacogenomic predictors
5. Thompson, C., Cheng, W. P., Gadad, P., Skene, K., Smith, M., Smith, G., McKinnon A, Knott R. (2011). Uptake and transport of novel amphiphilic polyelectrolyte-insulin nanocomplexes by caco-2 cells-towards oral insulin. Pharmaceutical Research, 28 (4), 886-896.
Page 12
Dr. Colin Thompson
PhD, MAPS, MRSC, FHEA
c.thompson@rgu.ac.uk
Researcher and lecturer in Drug Delivery
Telephone
ResearchGate https://www.researchgate.net/profile/Colin_Thompson Orcid Link http://orcid.org/0000-0002-9571-9434 RGU Link http://www.rgu.ac.uk/dmstaff/thompson-colin
+44 (0) 1224 262561
Dr Thompson has been an undergraduate, postgraduate and research fellow within the School and a lecturer in Drug Delivery since July 2009.
Research Interests •Targeted • drug delivery via I/V route using polymeric nanoparticles and polymer-drug conjugates
He teaches a variety of undergraduate modules across all four years on the MPharm course as well as other life sciences undergraduate and postgraduate degrees. He is also a Fellow of the Higher Education Academy and a Member of the Academy of
•Buccal • delivery of drugs using natural and semi-synthetic polymers
Pharmaceutical Sciences and the Royal Society of Chemistry.
1. Ibie, C. O., Knott, R. and Thompson, C. J., 2015. In-vitro evaluation of the effect of polymer structure on uptake of novel polymer-insulin polyelectrolyte complexes by human epithelial cells. International Journal of Pharmaceutics 479, 103-117. 2. Thompson, C.J., Hansford, D., Higgins, S., Rostron, C., Hutcheon, G.A. and Munday, D.L., 2009. Preparation and evaluation of microspheres prepared from novel polyester-ibuprofen conjugates blended with non-conjugated ibuprofen. Journal of Microencapsulation 26(8), 676-683. 3. Chemically Modified Polyelectrolytes for Intestinal Peptide and Protein Delivery, by C. Thompson and W. P. Cheng. In: Peptide and Protein Delivery, C Van der Walle (Ed.). Elsevier: London, 2011. 4. Cheng, W. P., Thompson, C., Ryan, S. M., Aguirre, T., Tetley, L. and Brayden, D. J., 2010. In vitro and in vivo characterisation of a novel peptide delivery system: Amphiphilic polyelectrolyte-salmon calcitonin nanocomplexes. Journal of Controlled Release 147(2), 289-297. 5. Thompson C. J., Cheng W. P., Gadad P., Skene K., Smith M., Smith G., McKinnon A., Knott R., 2011. Uptake and Transport of Novel Amphiphilic Polyelectrolyte-Insulin Nanocomplexes by Caco-2 Cells-Towards Oral Insulin. Pharmaceutical Research, 28(4), 886-896.
•Solid • lipid nanoparticles and nanostructured lipid carriers for drug solubilisation and delivery •Amphiphilic • polymers and polyelectrolytes for macromolecule delivery •Microencapsulation • of drugs using biodegradable polymers Page 13
Prof. Paul Kong Thoo BSc PhD FRSC CChem FHEA ResearchGate https://www.researchgate.net/profile/Paul_kong_thoo_lin Orcid Link http://orcid.org/0000-0002-7090-246X RGU Link http://www.rgu.ac.uk/dmstaff/kong-thoo-lin-paul
Since joining RGU, Prof. Kong Thoo Lin has
plants materials and the study of their biological
been active in the design and synthesis of
activities that can potentially be developed to fight
novel compounds/polymers with ‘intelligent’
neurodegenerative diseases.
functions that can be applied as sensors, parasites), to elucidate mechanism of drug action and provide effective drug delivery.
+44 (0) 1224 262818 Research Interests •Targeting • Histone Deacetylase Enzymes with novel compounds in cancer cell lines
From 1987 till 1992, Professor Paul Kong Thoo Lin worked at the MRC, Laboratory of Molecular Biology, Cambridge, UK, where he was involved in the synthesis of novel degenerate/universal bases
More recently his research has included the
p.v.s.kong-thoo-lin@rgu.ac.uk Telephone
Professor of Medicinal Chemistry
to treat and manage diseases (cancer and
and their incorporation in oligonucleotides.
isolation and identification of novel compounds from
1. Renato Gil, Célia G. Amorim, Laura Crombie, Paul Kong Thoo Lin, Alberto Araújo and Maria da Conceição Montenegro. Study of a novel bisnaphthalimidopropyl polyamine as electroactive material for perchlorate-selective potentiometric sensors (2015). Electroanalysis, 27, 1 – 12 (DOI: 10.1002/elan.201500275)
2. Jennifer Noro, Joana Maciel, Diana Duarte, Ana Cristina Dias Olival, Catarina Baptista, Anabela Cordeiro da Silva, Maria José Alves, Paul Kong Thoo Lin. Evaluation of New Naphthalimides as Potential Anticancer Agents Against Breast Cancer MCF-7, Pancreatic Cancer BxPC-3 and Colon Cancer HCT-15 Cell Lines (2015). Organic Chem Curr Res, 4:2 http://dx.doi. org/10.4172/2161-0401.1000144. 3. Gemma A. Barron, Marie Goua, Isao Kuraoka, Giovanna Bermano, Shigenori Iwai, Paul Kong Thoo Lin. Bisnaphthalimidopropyl diaminodicyclohexylmethane induces DNA damage and repair instability in triple negative breast cancer cells via p21 expression. Chemico-Biological Interactions 242 (2015) 307-315. 4. Marcela A. Segundo, Vera L. R. G. Abreu, Marcelo V. Osório, Sonia Nogueira, Paul Kong Thoo Lin, Anabela Cordeiro-da-Silva , Sofia A. C. Lima. Development and validation of HPLC method with fluorometric detection for quantification of bisnaphthalimidopropyldiaminooctane in animal tissues following administration in polymeric nanoparticles. Journal of Pharmaceutical and Biomedical Analysis. 120 (2016) 290–296.
•Regulation • of apoptosis and DNA damage in cancer cells •Design • and synthesis of multi target molecules against cancer •Anti-inflammatory • drug design based on natural products •The • design and application of novel drug delivery systems •Chemical • profiling and biological activities of plant pomace extracts
Page 14
Prof. Linda A. Lawton
BSc PhD
l.lawton@rgu.ac.uk
Professor of Environmental Microbiology
Telephone
ResearchGate https://www.researchgate.net/profile/Linda_Lawton Orcid Link http://orcid.org/0000-0002-7840-5310 RGU Link http://www.rgu.ac.uk/dmstaff/lawton-linda
+44 (0) 1224 262823
Prof. Lawton leads an internationally-
of microcystins, the main group of cyanotoxins.
respected research team, CyanoSol, which has
This methodology has now been published as an
a world wide reputation in the study of the
approved method and has been cited over 600
environmental impact and monitoring of natural
times in scientific literature. Her research has now
toxic metabolites from cyanobacteria (blue-
extended into broader environmental concerns
green algae).
such as desalination and waste valorisation through using green chemical and biotechnology. She has
These toxins pose a significant and increasing risk to human health in both drinking water and at recreational sites hence much of the work is involved in water treatment strategies including advanced oxidative techniques. Her group has pioneered the most widely used analytical procedure for analysis
successfully attracted funding from a wide range of sources including the Research Councils, EU, Charities and Industry. The reputation of her group has led to many fruitful research collaborations both in the UK and around the world including, Germany, Finland, Denmark, Poland, Cyprus, Spain & France.
1. Lack of functional redundancy in the relationship between microbial diversity and ecosystem functioning, M Delgado Baquerizo, L Giaramida, PB Reich, AN Khachane, K Hamonts, C Edwards, LA Lawton, BK Singh Journal of Ecology 2016 DOI: 10.1111/1365-2745.12585 2. Simultaneous cellulose conversion and hydrogen production assisted by cellulose decomposition under UV-light photocatalysis G Zhang, C Ni, X Huang, A Welgamage, LA Lawton, PKJ Robertson, JTS Irvine, Chemical Communications 52 (8), 16731676, 2016 DOI: 10.1039/c5cc09075j 3. Photocatalytic degradation of eleven microcystin variants and nodularin by TiO2 coated glass microspheres CJ Pestana, C Edwards, R Prabhu, PKJ Robertson, LA Lawton Journal of hazardous materials 300, 347-353, 2015 DOI: 10.1016/j.jhazmat.2015.07.016 4. Rapid bioassay-guided isolation of antibacterial clerodane type diterpenoid from Dodonaea viscosa (L.) Jaeq International Journal of Molecular Sciences M Khurram, LA Lawton, C Edwards, M Iriti, A Hameed, MA Khan, FA Khan, International journal of molecular sciences 16 (9), 20290-20307, 2015
Research Interests •Production, • detection and removal of cyanotoxins including microcystins, cylindrospermopsin and neurotoxins •Isolation • and characterisation of bioactive compounds from cyanobacteria and other novel biological sources •Algal • biotechnology for biofuels, material and food additives (omega-3, vitamins, pigments) •Water • quality, treatment and advanced oxidative methods for drinking water and waste water remediation •Application • of photocatalytic technologies to environmentally sustainable energy and chemicals Page 15
Dr. Lindsey Masson
BSc, MSc, PhD, RNutr
l.f.masson@rgu.ac.uk
Researcher and Lecturer in Nutrition
Telephone
ResearchGate https://www.researchgate.net/profile/Lindsey_Masson Orcid Link http://orcid.org/0000-0002-3760-8189 RGU Link http://www.rgu.ac.uk/lindsey-masson
+44 (0) 1224 262856 Research Interests
Dr Masson’s main area of expertise is in
joining Robert Gordon University, she was employed
the use of dietary assessment methods in
by the University of Aberdeen This included 4 years
epidemiological studies (of both children and
as a Research Fellow in Epidemiology, and 6 years as
adults), statistical analysis of epidemiological
a Lecturer in Human Nutrition Epidemiology which
studies (including studies with a complex
included acting as Programme Coordinator for the
survey design), and systematic review
MSc Human Nutrition and Metabolism.
methodology. Lindsey is also a member of the Nutrition Society Scottish Section committee.
Dr Masson is a Registered Nutritionist with the UK Voluntary Register of Nutritionists, held by the
She obtained her BSc (Hons) Health Sciences, MSc
•Monitoring • food and nutrient intakes in Scotland •Use • of dietary assessment methods in epidemiological studies of cardiovascular disease, cancer and obesity •Improving • diet in cancer survivors
Association for Nutrition.
Human Nutrition and Metabolism, and PhD Human Nutrition from the University of Aberdeen. Before
•Systematic • literature reviews on gene-diet interactions, genotypedisease associations, and dietdisease associations
1. Macdiarmid JI, Wills WJ, Masson LF, Craig LC, Bromley C, McNeill G. (2015) Food and drink purchasing habits out of school at lunchtime: a national survey of secondary school pupils in Scotland. Int J Behav Nutr Phys Act 12(1):98. doi: 10.1186/ s12966-015-0259-4. 2. Thies F, Masson LF, Bofetta P and Kris-Etherton P. (2014) Oats and CVD risk markers: a systematic literature review. Br J Nutr 112(Suppl 2): S19-30. doi: 10.1017/S0007114514002281. 3. Thies F, Masson LF, Bofetta P and Kris-Etherton P. (2014) Oats and bowel disease: a systematic literature review. Br J Nutr 112(Suppl 2): S31-43. doi: 10.1017/S0007114514002293. 4. Thies F, Masson LF et al. (2012) Effect of a tomato-rich diet on markers of cardiovascular risk in moderately overweight, disease-free, middle-aged adults: a randomised controlled trial. Am J Clin Nutr 95(5): 1013-22. doi: 10.3945/ajcn.111.026286. 5. Masson LF et al. (2012) Survey of Diet Among Children in Scotland. (2010). Volume 1: Diet, Obesity and Physical Activity. Food Standards Agency in Scotland. http://www.foodstandards.gov.scot/survey-diet-among-children-scotland
Page 16
Dr. Kerr H. Matthews
BSC(Hons) PhD CChem MRSC MAPS
k.h.matthews@rgu.ac.uk
Researcher and Lecturer in Pharmaceutics
Telephone
ResearchGate https://www.researchgate.net/profile/Kerr_Matthews Orcid Link http://orcid.org/0000-0002-8503-7157 RGU Link http://www.rgu.ac.uk/kerr-matthews
+44 (0) 1224 262525
Dr Matthews has research interests in the
Following his PhD in 1989, Dr Matthews’ expertise
general area of pharmaceutics. Since filing an
in polymer science has been applied in diverse areas
international patent on ‘Wafers for wounds’ in
of commercial interest from the manufacture of
2003, he has continued with the development
video tapes (3M UK Ltd.) to laminated papers (James
of this foundation technology as a topical
River Corp.); high tensile fibres and conducting gels
antimicrobial dressing, whilst teaching and
for lithium batteries (IRC in Polymer Science and
supervising at both undergraduate and
Technology, University of Leeds); artificial arteries
postgraduate levels.
and biomaterials (N.A.I.R., Japan); drug delivery
Research Interests •Antimicrobial • wafers as topical delivery systems for chronic wounds •Solid • and liquid drug delivery systems – design and manufacture
systems (Scherer DDS Ltd.); tissue repair & wound He has authored/co-authored 55 publications, including a book chapter, and has over 1000 citations.
healing (Pfizer) and topical antimicrobial therapies (RGU).
A review of drug delivery dressings co-authored in 2008 has been cited 570 times as of May 2016, placing it in the top 1% of its academic field.
Following a return to academia as a Lecturer in 2002 (University of Strathclyde) he subsequently moved to
•Hydrogels • – natural, synthetic and semi-synthetic polymers for pharmaceutical and biomedical application
Robert Gordon University in 2004.
•Biomaterials • 1. Bibi, S., Bremner, D.H., Macdougall-Heasman, M., Reid, R., Simpson, K., Tough, A., Waddell, S., Stewart, I.J., Matthews, K.H. 2015. A preliminary investigation to group disparate batches of licit and illicit diazepam tablets using differential scanning calorimetry. Anal.Methods., 7, 8597-8604. DOI: 10.1039/C5AY01711D 2. Labovitiadi, O., O’Driscoll, N.H., Lamb, A.J., Matthews, K.H. 2013. Rheological properties of gamma-irradiated antimicrobial wafers and in vitro efficacy against Pseudomonas aeruginosa, Int.J.Pharm., 453(2), 462-472. DOI: 10.1016/j.ijpharm.2013.06.005] 3. Labovitiadi, O., Lamb, A.J., Matthews, K.H. 2012. Lyophilised wafers as vehicles for the topical release of chlorhexidine digluconate – release kinetics and efficacy against Pseudomonas aeruginosa. Int.J.Pharm., 439(1-2), 157-164. DOI: 10.1016/j. ijpharm.2012.10.017 4. Boateng, J.S., Matthews, K.H., Stevens, H.N.E., Eccleston, G.M., 2008. Wound healing dressings and drug delivery systems - a review. J.Pharm.Sci., 97(8), 2892-2923. DOI: 10.1002/jps.21210
•Materials • Science – rheology and thermoanalytical techniques •Characterisation • of counterfeit medicines Page 17
Dr. Barbara McKenzie
MPharm PhD MRSC
b.mckenzie1@rgu.ac.uk
Lecturer in Pharmaceutics
Telephone
ResearchGate https://www.researchgate.net/profile/Barbara_Buchan Orcid Link http://orcid.org/0000-0003-0409-908X RGU Link http://www.rgu.ac.uk/dmstaff/mckenzie-barbara
+44 (0)1224 262588
Dr McKenzie’s area of expertise is the
chemicals, from medicines to cosmetics. The current
formulation of medicines and particularly the
focus of her research is to establish an equivalent
formulation of ophthalmic and respiratory
technique which uses fertilised hen’s egg placental
medicines. She has investigated the potential
membranes. She has established a method which
to deliver medicines systemically, using
uses computer software to categorise the level of
biodegradable coatings for drugs with
irritation, using a technique which has been used by
challenging stability profiles.
forensic scientists.
Dr McKenzie has also developed an ophthalmic
Dr McKenzie is currently working with engineers
gel for the treatment of ocular complications of the
to develop an ex-vivo ophthalmic model, to aid the
rare disease Nephropathic cystinosis, and recently,
understanding of drug retention within the cornea
her work has centred on developing a quantitative
and ophthalmic tissues. Part of this work also involves
technique to measure ophthalmic irritation.
microdialysis, a technique designed to measure drug
Historically, the Draize rabbit test has been used
concentration within the aqueous humor.
Research Interests •Ophthalmic • drug delivery using gels and in-situ gelling polymers •Nephropathic • cystinosis, its complications and its treatment •Pulmonary • delivery of drugs for systemic delivery •Rectal • drug delivery for systemic treatment
widely to determine the ophthalmic irritation of many
. 1. Buchan B, Kay G, Heneghan A, Matthews KH, Cairns D. Gel formulations for treatment of the ophthalmic complications in cystinosis. International Journal of Pharmaceutics. 2010; 392, 1-2, p. 192-197. 2. Buchan B, Kay G, Matthews KH, Cairns D. Suppository formulations as a potential treatment for nephropathic cystinosis. Journal of Pharmaceutical Sciences. 2012; 101, 10, p. 3729-3738. 3. McKenzie B, Kay G. Eye gels for ophthalmic delivery. Expert review of Ophthalmology. 2015; 10(2), 127-133. 4. McKenzie B, Kay G, Matthews K H, Knott RM., & Cairns D. The hen’s egg chorioallantoic membrane (HET-CAM) test to predict the ophthalmic irritation potential of a cysteamine-containing gel: Quantification using Photoshop® and ImageJ. International Journal of Pharmaceutics. 2015; 490 (1–2), 1–8.
Page 18
Dr. Wolfram Meier-Augenstein PHd
w.meier-augenstein@rgu.ac.uk
Professor
Telephone
Orcid Link http://orcid.org/0000-0002-0148-5332 RGU link http://www.rgu.ac.uk/dmstaff/meier-augenstein-wolfram
+44 (0) 1224 2500
Chemical analyses carried out in most analytical
While conventional spectroscopic and spectrometric
laboratories and, in particular in forensic science
methods prove chemical identity an argument can
laboratories primarily aim for the identification
be brought forward as a defence that although two
and comparison of various samples with the
substances in question are chemically identical they
intention of linking the samples of concern to a
are not the same, i.e. not of the same origin, hence
specific person or event. Identification is often
coming from a different source. Stable isotope
achieved through the characterization of one
analysis permits this contention to be tested since
or more specific sample constituents, while
it can provide the answer to the questions if two
comparison often involves the identification and
compounds or substances are truly identical, the
quantification of multiple components in the
given compound / substance can be linked to a
samples of interest.
particular geographic region.
1. W. MEIER-AUGENSTEIN, H.F. Kemp, E. R. Schenk, and J. R. Almirall (2014): “Discrimination of unprocessed cotton on the basis of geographic origin using multi-element stable isotope signatures”; Rapid Communications in Mass Spectrometry, 28, 545-552; DOI: http://dx.doi.org/10.1002/rcm.6811. 2. N. NicDaéid, S. Jayamana, W.J. Kerr, W. MEIER-AUGENSTEIN and H.F. Kemp (2013): “Influence of precursor solvent extraction on stable isotopic signatures of methamphetamine prepared from pseudo-ephedrine extracted from over the counter medicines using the Moscow and Hypophosporous routes”; Analytical and Bioanalytical Chemistry, 405 (9), 2931-2941; DOI: http://dx.doi. org/10.1007/s00216-012-6600-8. 3. N. NicDaéid, W. MEIER-AUGENSTEIN, H.F. Kemp and O.B. Sutcliffe (2012): “Using isotopic fractionation to link precursor to product in the synthesis of (±)-mephedrone. A new tool for combating ‘legal high’ drugs”; Analytical Chemistry, 84, 8691-8696; DOI: http://dx.doi.org/10.1021/ac3019069. 4. W. MEIER-AUGENSTEIN, H.F. Kemp and S. Hardy (2012): “Detection of Counterfeit Scotch Whisky by Bulk 2H and 18O Stable Isotope Analysis”; Food Chemistry, 133, 1070-1074; DOI: http://dx.doi.org/10.1016/j.foodchem.2012.01.084.
Research Interests •Human • provenancing •Elucidating • shifts in stable isotopic composition of synthetic drugs to link precursor/s to product •Elucidating • shifts in stable isotopic composition of explosives to link precursor(s) to product •Determining • authenticity and provenance of food by way of stable isotope analysis •Determining • authenticity and provenance of pharmaceutical drugs by way of stable isotope analysis Page 19
Dr. Simon Officer
BSc(Hons) PhD MRSC
s.officer@rgu.ac.uk
Researcher and Lecturer in Analytical and Pharmaceutical Analysis
Telephone
ResearchGate https://www.researchgate.net/profile/Simon_Officer Orcid Link http://orcid.org/0000-0002-4126-0875 RGU Link http://www.rgu.ac.uk/dmstaff/officer-simon
+44 (0) 1224 262370 Research Interests
Dr Officer lecturers with expertise in
his PhD entitled “Alternative Strategies for Security
spectroscopy and laser based sensing having
Labelling/Encoding of Paper and Plastic Products”
been involved in a number of related research
in 2005 from The Robert Gordon University.
projects over the last 15 years. This has
Following this, he carried out his postdoctoral
involved applications of fluorescence sensing,
research advancing the technology developed from
UV excimer curing of surfaces, development
his PhD and helped expand the applications into the
of optical/polymeric materials including glass,
biomedical and environmental fields. This involved
development of photocatalytic coatings and
working on various projects funded by industry
fluorescent taggants.
(NCR Financial Solutions Group Ltd, Dundee, ITI
•Synthesis • and spectral analysis of lanthanide complexes for a variety of applications •Sol-gel • synthesis of nano and micro sized beads •Spectroscopy • and laser based sensing
Techmedia and Prime Technologies LLC) which led Dr Officer gained his 1st Class BSc Honours degree in Applied Chemistry in 2001 before completing
•Development • of a novel latent fingerprint development powder
to filing three patents. He was appointed as a lecturer in the School of Pharmacy & Life Sciences in 2008.
•Development • of a novel environmental soil tracer 1. CRUICKSHANK, L., OFFICER, S., POLLARD, P., PRABHU, R., STUTTER, M. AND FERNANDEZ, C., 2015, Rare Elements Electrochemistry: The Development of a Novel Electrochemical Sensor for the Rapid Detection of Europium in Environmental Samples Using Gold Electrode Modified with 2-pyridinol-1-oxide, Analytical Sciences, 31(7), pp. 623-627. doi:10.2116/analsci.31.623. 2. HAUSER, F.M., KNUPP, G. and OFFICER, S., 2015, Improvement in fingerprint detection using Tb(III)-dipicolinic acid complex doped nanobeads and time resolved imaging, Forensic Science International, 253, pp. 55-63. doi:10.1016/j.forsciint.2015.05.010
.
3. TIM CUSHNIE, T.P., ROBERTSON, P.K.J., OFFICER, S., POLLARD, P.M., MCCULLAGH, C. and ROBERTSON, J.M.C., 2009, Variables to be considered when assessing the photocatalytic destruction of bacterial pathogens, Chemosphere, 74(10), pp. 1374-1378. doi:10.1016/j.chemosphere.2008.11.012. 4. POLLARD, P., ADAMS, M., ROBERTSON, P.K.J., CHRISTIDIS, K., OFFICER, S., PRABHU, G.R., GOW, K., and MORRISON, A.R., 2008, Environmental Forensic Investigations: The Potential Use of a Novel Heavy Metal Sensor and Novel Taggants, In: K. RITZ, L. DAWSON and D. MILLER, ed. Criminal and Environmental Soil Forensics. Aberdeen: Springer. pp. 477-490
Page 20
Dr. Iain Rowe
PHd
i.rowe@rgu.ac.uk
Lecturer
Telephone
ResearchGate https://www.researchgate.net/profile/Simon_Officer Orcid Link http://orcid.org/0000-0002-0148-5332 RGU link http://www.rgu.ac.uk/dmstaff/rowe-iain
+44 (0) 1224 2546
Dr Rowe is a Lecturer in Biomedical Science
Ongoing projects include work with Dr Stuart
at RGU with laboratory research focussed on
Cruickshank and Dr Helene Widmer (RGU) on:
electrophysiological and imaging techniques
the pulmonary vein as a therapeutic target in
to investigate: (i) the biophysical relationship
cardiovascular disease; the use of bioinformatics to
between potassium channel structure and
support the utilisation of farm animal tissue for more
function; (ii) post-translation modification
effective preclinical screening; and utilisation of data
of channel activity by metabolic signals and
on single-nucleotide polymorphisms to investigate ion
pharmacology; and (iii) the pharmacological
channel function. Non-laboratory research involves
modulation and physiological impact of
investigation of: the role of inter-professional learning
potassium channels in complex biological
(IPL); quality improvement methodology; and
systems.
cloud-based resources in pharmacy and biomedical
Research Interests
•Potassium • channel physiology •Potassium • channel pharmacology •Metabolic • regulation of ion channels
education.
•Ion • channels in pulmonary tissue 1. Ciprian Dopinescu, Helene Widmer, Iain Rowe, Cherry Wainwright, Dorothy McCaig & Stuart Cruickshank. (2012) Hypoxia sensitivity of a voltage-gated potassium current in porcine intrapulmonary vein smooth muscle cells. Am. J.Physiol. (Lung Cell. Mol.Physiol.) 303, L476-86.
•Hypothalamic • control of appetite
2. Saleem F, Rowe ICM & Shipston MJ. (2009) Characterisation of BK channel splice variants using membrane potential dyes. Br. J.Pharmacol. 156, 143-152 3. McCartney, C.E., Huibant, J-M., McClaffery, H., Rowan, E.G., Shipston, M.J. & Rowe, I.C.M. (2005) A cysteine rich motif confers hypoxia sensitivity onto mammalian large conductance voltage and calcium activated (BK) channel α subunits. Proc. Natl. Acad. Sci. USA. 102, 17870-17875 4. Rowe, I.C.M., Lee, K., Khan, R.N. & Ashford, M.L.J. (1997) Englitazone inhibits KATP and non-selective cation channels in CRI-G1 insulin-secreting cells. Br. J. Pharmacol. 121, 531-539. 5. Rowe, I.C.M., Boden, P.R. & Ashford, M.L.J. (1996) Potassium channel dysfunction in hypothalamic glucose-receptive neurones of obese Zucker rats. J. Physiol. 497.2, 365-377.
Page 21
Dr. Kyari Yates
k.yates@rgu.ac.uk
BEng MSc PhD
Researcher, Environmental Chemistry; Lecturer, Forensic & Analytical Sciences, ResearchGate https://www.researchgate.net/profile/Kyari_Yates Orcid Link http://orcid.org/0000-0002-9919-4516 RGU Link http://www.rgu.ac.uk/dmstaff/yates-kyari
Dr Yates’s research interest lies in
He worked as an environmental Chemist at the
environmental chemistry with a particular
Fisheries Research Services Marine Laboratory
emphasis on fate, distribution and effects
(now Marine Scotland Science Marine Laboratory)
of persistent organic pollutants (POPs) and
Aberdeen before joining the Macaulay Land Use
passive sampling methodologies in various
Research Institute, Aberdeen (now James Hutton
matrices.
Institute) where he worked as an Analytical Chemist.
Dr Yates also has an interest in environmental sensing
In 2010 he was appointed a Lecturer with the School
and monitoring as well as the recycling of used
of Pharmacy and Life Sciences at RGU.
drilling fluids and remediation of oily waste waters.
1. Adegbotolu, V. U., Njuguna, J., Pollard, P., and Yates, K. (2014). Waste to Want: Polymer nanocomposites using nanoclays extracted from Oil based drilling mud waste. IOP Conf. Ser.: Mater. Sci. Eng. 64 012023 doi:10.1088/1757-899X/64/1/012023
Telephone
+44 (0) 1224 262884
Research Interests •• Fate, distribution and effects of persistent organic pollutants (POPs) •Development • of analytical methodologies for environmental monitoring •Passive • sampling methodologies in various matrices •Recycling • of used drilling fluids and cuttings
2. Yates, K., Pollard P., Davies, I.M, Webster, L., and Moffat, C. (2013) Silicone rubber passive samplers for measuring pore water and exchangeable concentrations of polycyclic aromatic hydrocarbons in sediments. Science of the Total Environment, 463-464: 988-996 3. Yates, K., Pollard P., Davies, I.M, Webster, L., and Moffat, C. (2011) Application of silicone rubber passive samplers to investigate bioaccumulation of PAHs in Nereis virens, Environmental Pollution 159 (12), pp 3351-3356 4. Rhind, S.M., Kyle, C.E., Mackie, C., Yates, K. and Duff, E.I. (2011) Geographic variation in tissue accumulation of endocrine disrupting compounds (EDCs) in grazing sheep, Environmental Pollution, 1519 (2), pp 416-422 5. Yates, K. Davies, I.M, Webster, L., Pollard P., Lawton, L., and Moffat, C. (2007) Passive sampling: Partition coefficients for a silicone rubber reference phase, Journal of Environmental Monitoring, Vol. 9, pp 1116-1121
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Practice RESEARCH Innovations in pharmacy practice • sustainable models of integrated multidisciplinary care • independent prescribing • pharmaceutical care • interprofessional learning • self-care • technology enhanced practice Medicines use • Medicine effectiveness and safety • specific medicine groups • individual medicines • Medicine processes and procedures Improving nutritional care • working with food suppliers • modification of food products
Prof. Derek Stewart BPharm (hons), MSc, PHd, PGCERT Clinical PracTICE THeme LEader
Professor of Pharmacy Practice, Lead for Practice Research, ResearchGate https://www.researchgate.net/profile/Derek_Stewart2 Orcid Link http://orcid.org/0000-0001-7360-8592 RGU Link http://www.rgu.ac.uk/derek-stewart Prof. Stewart leads the Clinical Practice theme.
organisations and society at local, national and
He has expertise in a wide spectrum of health
international levels. He has an international reputation
services research methodologies and methods.
in the field on non-medical prescribing education,
His research spans very many different
policy, practice and research.
practice research areas, with particular focus on developing, implementing and evaluating models of care, and the safe and effective use of medicines.
He collaborates widely with academics and practitioners across the globe and is currently leading
d.stewart@rgu.ac.uk Telephone
+44 (0) 1224 262432 Research Interest •Development, • implementation and evaluation of non-medical prescribing models of practice; appropriate prescribing in all patients groups, particularly older people
major research programmes in the Middle East and is a key player in a European Commission funded
He has led pharmacy practice research generating
study of inappropriate polypharmacy being led by the
evidence of impact on patients, professionals,
Scottish Government.
1. Alqubaisi M, Tonna A, Strath A, Stewart D. Exploring behavioural determinants relating to health professional reporting of medication errors: a qualitative study using the Theoretical Domains Framework. European Journal of Clinical Pharmacology 2016;72:887895.DOI 10.1007/s00228-016-2054-9 2. McLay JS, Pallivalappila AR, Shetty A, Pande B, Moza Al Hail, Stewart D. ‘Asking the Right Question’. A Comparison of Two Approaches to Gathering Data on ‘Herbals’ Use in Survey Based Studies. PLoS ONE 11(2): e0150140. DOI:10.1371/journal. pone.0150140 3. Al Shemeili S, Klein S, Strath A, Fares S, Stewart D. An exploration of health professionals’ experiences of medicines management in elderly, hospitalised patients in Abu Dhabi. International Journal of Clinical Pharmacy 2016;38:107-118.DOI 10.1007/s11096015-0212-2 4. Tucker R, Stewart D. An exploratory study of the views of community pharmacists on the management of patients with undiagnosed skin problems. International Journal of Pharmacy Practice 2015;23:390-398DOI 10.1111/ijpp.12179 5. Rushworth GF, Diack L, MacRobbie A, Munoz SA, Pfleger S, Stewart D. Access to medicines in remote and rural areas: a survey of residents in the Scottish Highlands & Western Isles. Public Health 2015;129:244-251.DOI: 0.1016/j.puhe.2015.01.005
•Patient • safety in general and medication errors specifically •Use, • effectiveness and harm associated with complementary and alternative medicines •Access • to medicines, particularly in remote and rural areas; development of strategies to reduce medication waste •Medicines • adherence, associated behavioural determinants Page 24
Dr. Scott Cunningham BSc (Hons) , PGDip, PHD
s.cunningham@rgu.ac.uk
Senior Lecturer,
Telephone
Orcid Link http://orcid.org/0000-0002-568 RGU Link http://www.rgu.ac.uk/scott-cunningham
+44 (0) 1224 2533
Dr Cunningham is a senior lecturer and group
researcher with research interests spanning many
leader for Clinical Pharmacy and Pharmacy
aspects of pharmacy practice and education.
Practice at the School of Pharmacy and Life Sciences.
Dr Cunningham is involved in researching aspects
Research Interests •Transdisciplinary • education and practice
of pharmacist prescribing including: the training He is a Chair of the Royal Pharmaceutical Society
programme, why some pharmacists choose to train
Faculty Accreditation Panel and has a broad interest in
as prescribers and others do not; how pharmacist
all aspects of quality assurance related to pharmacist
prescribers actually practise; the views of the
development. Dr Cunningham is an external examiner
pharmacist prescribers and their doctor colleagues.
for pharmacy courses and regularly reviews for a
•Pharmacist • prescribing and e-Health implementation •Medication • Adherence in Chronic conditions
number of journals. Dr Cunningham is an active
•Remote • and Rural Healthcare 1. FITZGERALD N, YOUNGSON E, CUNNINGHAM S, WATSON M, STEWART D. Support for community pharmacy-based alcohol interventions: A Scottish general public survey. Public Health. 2015 129(11):1431-8. DOI: 10.1016/j.puhe.2015.07.005 2. HOGAN-MURPHY, D., TONNA, A., STRATH, A. and CUNNINGHAM, S. 2015. Healthcare professionals’ perceptions of the facilitators and barriers to implementing electronic systems for the prescribing, dispensing and administration of medicines in hospitals: a systematic review. European Journal of Hospital Pharmacy [online], 22(6), 358-365. DOI: 10.1136/ejhpharm-2015-000722 3. STEWART D, GENERALOVA D, CUNNINGHAM S, LESLIE S, RUSHWORTH G, MCIVER L. Healthcare professional and patient views, behaviours and experiences surrounding novel oral anticoagulants (NOACs) for the management of non-valvular atrial fibrillation (AF): a systematic review protocol. PROSPERO 2016: CRD42016003840. 4. MACLURE K, MACLEOD J, FORBES-MCKAY K, CUNNINGHAM S, PAUDYAL V, LYNCH R, STEWART D. A case study investigation into the use of multi-compartment compliance aids in older people resident in very sheltered housing. The Patient: Patient– Centered Outcomes Research. 2016. In press. DOI: 10.1007/s40271-016-0178-8.
Page 25
PROF. Lesley DIack
PhD
h.l.diack@rgu.ac.uk
Professor in Transdisciplinary and Technology Enhanced Learning
Telephone
ResearchGate https://www.researchgate.net/profile/Lesley_Diack Orcid Link http://orcid.org/0000-0002-0037-7794 RGU Link http://www.rgu.ac.uk/dmstaff/diack-lesley/
+44 (0) 1224 262511
Professor Lesley Diack has worked at RGU since
the Centre for the Advancement of Interprofessional
2003, actively working on and researching
Education in Scotland, one of only a few Principal
transdisciplinary and technology enhanced
Fellows of the Higher Education Academy as well as
learning. She was the principal investigator on
a Certified Member of the Association of Learning
a Scottish Government funded Interprofessional
Technology. She has presented widely on education
Education (IPE) project and author of the 2008
and technology topics nationally and internationally
report.
and has published articles on both.
•Technology • Enhanced Learning
She has worked on other funded IPE and pedagogical
Prior to coming to RGU Professor Diack worked as a
projects totalling over £1.2m, including projects with
lecturer and researcher at the University of Aberdeen
Police Scotland, Cancer Link Aberdeen and the North
for a number of years including a Wellcome funded
•Mobile • Apps for Health and social care
(CLAN), Janssen-Cilag, and with collaborators in
project investigating the Aberdeen Typhoid Outbreak
Japan and Qatar. She is the only Honorary Fellow of
of 1964.
Research Interests •Transdisciplinary • education and practice
•Social • media use for health and health professional •Patient • care pathways
1. El-Awaisi, A., Diack, L., Joseph, S., El Hajj, M. (2016) Perspectives of pharmacy students, pharmacy academics and practicing pharmacists on interprofessional education and collaborative practice: a comprehensive systematic review protocol. JBI Database of Systematic Reviews and Implementation Reports DOI: 10.11124/jbisrir-2015-2115
•Innovation •
2. Diack, L., Joseph, S., Garton, F., Haxton, J. (2015) Reflecting on delivering Interprofessional education in practice. Journal of Practice Teaching and Learning 13(2-3) pp32-44. 3. Stewart, D. Al Hail, M., Rouf PVA., Diack, L., [...], Awaisu, A. (2015) Building hospital pharmacy practice research capacity in Qatar: a cross-sectional survey of hospital pharmacists. International Journal of Clinical Pharmacy 37(3):511-21. DOI: 10.1007/s11096015-0087-2 4. Joseph, S., Diack, L. (2015) Playing interprofessional games: reflections on using the Interprofessional Education Game (iPEG). Journal of Interprofessional Care 29(3): 260-262. DOI: 10.3109/13561820.2014.942839 5. Rushworth, G., Diack, L., Rudd, I., Stewart, D. (2015) General practitioner views of an electronic high-risk medicine proforma to facilitate information transfer. International Journal of Clinical Pharmacy 37(1):4-7 DOI: 10.1007/s11096-014-0033-8
Page 26
Dr. Katie MacLure
PhD, MSc, BSc (Hons), DipSysPrac, PgCert
k.m.macLure@rgu.ac.uk
Senior Research Fellow & Lecturer,
Telephone
ResearchGate https://www.researchgate.net/profile/Katie_Maclure Orcid Link http://orcid.org/0000-0003-0686-948X RGU Link http://www.rgu.ac.uk/dmstaff/maclure-katie
+44 (0) 1224 2556 Research Interests
Dr Maclure has expertise in a wide range of
Middle East and a European Commission funded
health services research with a particular
study of inappropriate polypharmacy being led by
interest in ehealth and digital literacy,
the Scottish Government. Closer to home, Katie’s
technology-enabled care, non-medical
research focus in Scotland includes evaluation of
prescribing (NMP), equality of care for
pharmacy dispensing technologies and pharmacist
disadvantaged groups and pharmacy practice.
access to clinical electronic health records.
Dr MacLure works with research partners across the
Dr Maclure also teaches undergraduate and
globe and is currently involved in a major research
postgraduate students qualitative and mixed methods
project around medication error reporting in the
approaches to research.
1. MacLure K, Paudyal V, Stewart D. (2016) Reviewing the literature, how systematic is systematic? International Journal of Clinical Pharmacy (in press) 2. Brown A, MacLure K, Addison B, Pedersen S, Stewart D. Professional body and regulatory organisation guidance on the use of social media for registered healthcare professionals: a systematic review protocol. PROSPERO 2016:CRD42016026877.
•eHealth: • in relation to pharmacy IT strategy, integrated healthcare and digital literacy •Pharmacy • practice and education: non-medical prescribing, consultation skills, pharmacovigilance, technology in pharmacy, role of pharmacy in care of older people •Research • Methods: with a focus on qualitative approaches, research governance, systems practice, systematic reviews
3. Tobaiqy M, Al Humaid S, Stewart D, Omear Alotaibi F, Ahmad Qureshi K, MacLure K, Algharib F, Alsameti A, Alsaqer A and Almeman A (2015) Assessment of Tigecycline Prescription and Patients’ Outcomes at Three Different Hospitals in Saudi Arabia. Trop J Pharm Res; 14(10): 1919 4. MacLure K, Stewart D (2015) Self-Reported Digital Literacy of the Pharmacy Workforce in North East Scotland. Pharmacy, 3, 182196; doi:10.3390/pharmacy3040182 5. MacLure K, Paudyal V, Stewart D (2015). Making better decisions based on medicines information: how to find and critically appraise relevant literature. ESCP conference (Lisbon, workshop)
Page 27
Dr. Myra MaCkenZie
PhD, HCPC registered dietitian
m.mackenzie3@rgu.ac.uk
Lecturer,
Telephone
Orcid Link http://orcid.org/0000-0002-5680-6287 RGU Link http://www.rgu.ac.uk/dmstaff/mackenzie-myra
+44 (0) 1224 2558
Dr Makenzie has research interests in
Following this, she worked as a clinical dietitian in a
the pedagogy of dietetic education and
variety of different roles, including paediatrics, cystic
in understanding the sociological and
fibrosis and enteral nutrition.
psychological determinants of dietary intake. Dr Mackenzie is a longstanding member of the British She qualified as a dietitian in 1980, and after 2 years
Dietetic Association, and sits on the Quality Standards
spent in a rotational post at Addenbrookes Hospital,
Committee for dietetic education. She is an HCPC
Cambridge, she undertook a PhD entitled ‘Diet
registered dietitian and a Senior Fellow of the Higher
and Functional Bowel disorders’ supervised jointly
Education Academy.
Research Interests •Nutrition • and hydration in the elderly •Gut • function and diet •Dietetic • pedagogy
by Dr Rodney Burnham at the London Hospital and Professor John Dickerson at the University of Surrey.
•Sociological • and psychological impacts on food choice
1. MACKENZIE, M. NEWMAN, E. and PASIEKA, E. (2016) Exploring social care placements in pre-registration dietetic education. Submitted to : International Journal of Practice-based Learning in Health and Social Care 2. CAWLEY, R. and MACKENZIE-FRASER, M. (2012) Validation of a food frequency questionnaire for estimating calcium intake in young female adults . Gut; 61:Suppl 2 A86 3. KUMARASAMY,Y., AGUILAR, G.E., GOMARIA,E., MACKENZIE-FRASER, M. (2011). Systematic review of the diagnostic accuracy of monitoring the nutritional status of patients with HIV/AIDS using a validated screening tool. Int. J Evidence based Health care. 10(3): 270 4. RODGERS, A and MACKENZIE-FRASER, M. (2011) Student Nurses’ training and attitudes towards the use of the Malnutrition Universal Screening Tool. Proceedings of the Nutrition Society 70, OCE5, E322 5. TRAVIS, H.E and MACKENZIE-FRASER, M. (2011) The accuracy of MUST assessments by staff in a care home setting. Proceedings of the Nutrition Society 70, 0CE5, E322
Page 28
Dr. Noëlle O’Driscoll
PhD MPharm MRPharmS SFHEA MAPS
n.o-driscoll@rgu.ac.uk
Lecturer in Pharmaceutical Microbiology
Telephone
ResearchGate https://www.researchgate.net/profile/Noelle_ODriscoll Orcid Link http://orcid.org/0000-0003-2146-4202 RGU Link http://www.rgu.ac.uk/staff/noelle-o-driscoll
Dr O’Driscoll’s research areas include the
veterinary pharmacy and the delivery of information
development of novel antimicrobial agents
to under/postgraduate pharmacists on veterinary
for clinical use, assessment of the public
medicines is also a main research theme.
understanding of antibiotic resistance and multi-drug resistant bacteria and most recently the use of mobile apps for educational and healthcare purposes.
Dr O’Driscoll is a Member of The Royal Pharmaceutical Society of Great Britain, the Academy of Pharmaceutical Sciences, the Infection Prevention Society and is a Senior Member of the Higher
Investigation of microbial contamination of
Education Academy. Prior to RGU, Dr O’Driscoll
CleanRooms, operators and products produced
worked extensively in community and hospital
within these areas is another longstanding area
pharmacy both in Scotland and Ireland.
of research.The interaction of pharmacists with
1. Cushnie, T.P.Tim, O’Driscoll, N.H., & Lamb, A.J. Morphological and ultrastructural changes in bacterial cells as an indicator of antibacterial mechanism of action. Cellular and Molecular Life Sciences 2016.DOI:10.1007/s00018-016-2302-2 2. O’Driscoll, N.H., Labovitiadi, O., and Lamb, A.J. Evaluation of the practice of Veterinary Pharmacy. Currents in Pharmacy Teaching and Learning. Vol. 7 (5), pp. 606-613.DOI:http://dx.doi.org/10.1016/j.cptl.2015.06.017, 2015-09 3. O’Driscoll, N.H., Juwah, C., Labovitiadi, O. and Lamb, A.J. Veterinary Pharmacy within the United Kingdom: Review of current practice and education. Pharmacy Education 2014; 14 (1) pp. 26-30. 4. O’Driscoll, N., Labovitiadi, O., Cushnie, TT., Matthews, KH. and Lamb, AJ. Potassium loss from chlorhexidine-treated bacterial pathogens is time- and concentration-dependent and variable between species. Current Microbiology 2015. 68 (1) pp 6-11. DOI:http://dx.doi.org/10.1007/s00284-013-0433-3 5. Labovitiadi, O., O’Driscoll, N.H., Lamb, A.J., and Matthews, K.H. Rheological properties of gamma-irradiated antimicrobial wafers and in vitro efficacy against Pseudomonas aeruginosa. International Journal of Pharmaceutics 2013 Sep 10; 453 (2):462-72. Doi:10.1016/j.ijpharm.2013.06.005.
+44 (0) 1224 262579 Research Interests •Novel • antimicrobials - the development of novel delivery/ formulation methods for existing antibacterial agent •Veterinary • Pharmacy - the prescribing, sale, supply and dispensing of veterinary medicines •Contact • Lenses - the assessment of the hygiene protocols and investigation of the microbial contamination •Aseptic • Suites - assessment and control of microbial contamination of CleanRooms, operators and products •Antibiotic • resistance Page 29
Prof. Alison Strath
FRPharmS
a.strath@rgu.ac.uk
Professor of Community Pharmacy Practice,
Telephone
ResearchGate https://www.researchgate.net/profile/Alison_Strath Orcid Link http://orcid.org/0000-0003-2489-8727 RGU Link http://www.rgu.ac.uk/dmstaff/strath-alison
+44 (0) 1224 2530
Professor Strath has active research interests
at the University of Dundee to develop, evaluate
in pharmacy practice, eHealth and models
and determine the effectiveness of a medical and
of community pharmacy remuneration.
pharmacy student teaching programme aimed at
Other interests include pharmacy education,
enhancing their interprofessional working.
interprofessional learning, pharmaceutical care, prescribing, medicine safety, patient safety, quality improvement and workforce development.
Professor Strath also works part-time with Scottish Government where she is responsible for developing and implementing new community pharmacy services and supporting the ePharmacy
She has attracted funding from NHS Education for
Technology Programme. This role includes policy
Scotland (NES) and the Higher Education Academy
development and implementation. She provided the
(HEA). One programme has led to the establishment
pharmaceutical input to the Scottish Government’s
of a joint academic fellow with the School of Medicine
H1N1 Pandemic Flu response in 2009.
1. Alqubaisi M, Tonna D, Strath A, Stewart D. Quantifying behavioural determinants relating to health professional reporting of medication errors: a cross-sectional survey using the Theoretical Domains Framework. European Journal of Clinical Pharmacology 2016;72:1401–1411. DOI: 10.1007/s00228-016-2124-z 2. Al Shemeili, S., Klein S., Strath A., Stewart, D. An exploration of health professionals’ experiences of medicines management in elderly, hospitalised patients in Abu Dhabi. International Journal of Clinical Pharmacy 2015; 38:107–118. DOI: 10.1007/s11096-0150212-2 3. Hogan-Murphy D., Tonna A., Strath A., Cunningham I.T.S. Healthcare professionals’ perceptions of the facilitators and barriers to implementing electronic systems for thr prescribing, dispensing and administration of medicines in hospitals: A systematic review. European Journal of Hospital Pharmacy 2015; 0:1-8. DOI: 10.1136/ejhpharm-2015-000722
Research Interests •Models • of pharmacy practice including eHealth technologies and remuneration models •Quality • improvement •Patient • safety, human factors and simulation in healthcare •Interprofessional • learning in undergraduate and postgraduate education •Healthcare • policy development and implementation
4. MacLure K., Stewart D., Strath A., A systematic review of medical and non-medical practitioners’ views on the impact of ehealth on shared care. European Journal of Hospital Pharmacy 2014; 21:54-62. DOI: 10.1136/ejhpharm-2013-000337 5. Regan K, Harney L, Goodhand K, Strath A and Vosper H. Pharmacy Simulation: A Scottish, Student-Led Perspective with Lessons for the UK and Beyond. Pharmacy 2014; 2:50-64. DOI:10.3390/pharmacy2010050
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Dr. Antonella Tonna
BPharm (hons), MSc, PHd,MRPharms, MFRPSII
a.tonna@rgu.ac.uk
Lecturer in Clinical Pharmacy
Telephone
ResearchGate https://www.researchgate.net/profile/Antonella_Tonna2 Orcid Link http://orcid.org/0000-tba RGU Link http://www.rgu.ac.uk/antonella-tonna
+44 (0) 1224 262578
Dr Tonna was previously a hospital pharmacist
research. She is also responsabile for facilitates
in Malta for around 10 years and was
workshops and student symposia as part of the
instrumental in setting up numerous services,
annual European Association of Hospital Pharmacists
mainly the ward based clinical pharmacy service
Congress.
in 2002. She moved to the UK and was involved in primary care research in Edinburgh and then worked as a clinical pharmacist at the John Radcliffe Hospital, Oxford.
Dr Tonna graduated with a BPharm (Hons) from the University of Malta in 1994. In 2001 she completed an MSc in Clinical Pharmacy at Robert Gordon University and graduated in 2001, completing a PhD in 2011.
Dr Tonna is a member of the Scottish Antimicrobial Pharmacists’ Association with a key role in developing
1. Alqubaisi M, Tonna A, Strath A, Stewart D. Exploring behavioural determinant relating to health professional reporting of medication errors: a qualitative study using the Theoretical Domains Framework. European Journal of Clinical Pharmacology: 2016: DOI: 10.1007/s00228-016-2054-9 2. Hogan-Murphy D, Tonna A, Strath A, Cunningham S. Healthcare professionals’ perceptions of the facilitators and barriers to implementing electronic systems for the prescribing, dispensing and administration of medicines in hospitals: a systematic review. European Journal of Hospital Pharmacy 2015: doi:10.1136/ejhpharm-2015-000722 3. Fleming A, Tonna A, O’Connor S, Byrne S, Stewart D. Antimicrobial stewardship activities in hospitals in Ireland and the United Kingdom: a comparison of two national surveys. International Journal of Clinical Pharmacy 2015: DOI 10.1007/s11096-015-0114-3
Research Interests •Antimicrobial • stewardship and the role of the pharmacist in optimising antimicrobial use •Exploring • individuals’ views and perceptions using qualitative research methods •Exploration • of patient and prescribing behaviour relating to antimicrobial prescribing and use •Exploring • patient and carer involvement in delivery of pharmacy education
4. Petrie K., O’Brien C., Bhushan S., Tonna A. Neonatal vancomycin trough level audit using British National Formulary for Children Dosing. Arch Dis Child Fetal Neonatal Ed published online December 17, 2014. 5. Tonna AP, Gould IM, Stewart D. A cross-sectional survey of antimicrobial strategies in UK hospitals. Journal of Clinical Pharmacy and Therapeutics 2014:39: 516-520. DOI: 10.1111/jcpt.12181
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