HELP FOR FIP® TREATMENT SUPPORT HANDBOOK

What is GS441524 and What Is the Truth?

GS-441524 is a nucleoside analogue antiviral drug that Gilead Sciences developed. It is the primary plasma metabolite of the antiviral prodrug Remdesivir, developed for human use.

Remdesivir and GS-441524 were both effective in vitro against feline coronavirus strains that cause FIP. Remdesivir was never tested in cats, although it's used in other countries.

GS-441524 is an effective treatment for FIP and is widely used despite no official FDA approval due to Gilead's refusal to license this drug for veterinary use.

As many people report, the FDA is NOT to blame for the lack of an available, prescribable cure. Therefore, it's unfair to scrutinize parents who seek out off-market FIP treatment— often at their veterinarian's recommendation. The ethical nature of their oath drives many veterinarians to advise their clients to find it. Cat owners desperately want to save their beloved family pet and have no choice but to find it themselves.

Gilead Sciences holds the patent, aka "the key" to curing tens of thousands of cats globally.

However, they chose not to proceed with FDA approval to make it legally available to prescribing veterinarians after the successful UC Davis 2017 drug trial. Here's their reasoning: Gilead Sciences is known for its antiviral drugs for treating HIV/AIDS, hepatitis B and C, influenza, and COVID-19. Gilead refuses to license the drug for animal use, fearing its similarity to Remdesivir (originally developed to treat Ebola) would interfere with the FDA approval process.

Chinese companies and others worldwide started manufacturing the GS compound to sell via various avenues. **A word of caution: Not all GS are created equal. The Help For FIP® advisors can help guide owners to the safest GS available. Be cautious of the first attractive websites in a Google search or the unsolicited texts or emails from persuasive scammers. A link to multiple brands' laboratory testing results is available upon request. These results may include purity, concentration, consistency, and pH (acidity) testing.

While the media zeroes in on the cost of this life-saving treatment, they neglect to report on this affordability and safety. Compared to 2019, the price of GS to the treating cat owner has drastically reduced, making it affordable to most owners. Never assume that what you're reading on the internet is the current data. In other words, please don't give up on treating your cat because you think the cost is what you see.

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