Sabin Vaccine Institute Brochure

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Changing Lives

through Science and Advocacy


Sabin Vaccine Institute is a leading nonprofit organization made up of scientists, researchers and advocates dedicated to improving the health of the world’s poorest citizens.

What We Do

More than 20 Years of Success

Our mission is to reduce needless suffering from vaccine-preventable and neglected tropical diseases by developing new vaccines, advocating for increased access to existing vaccines and promoting expanded access to affordable medical treatments.

Since 1993, Sabin Vaccine Institute (Sabin) has been at the forefront of the global effort to reduce the burden of vaccine-preventable diseases and diseases that perpetuate poverty. Our approach relies on scientific innovation, coupled with advocacy, communications and partnership. From launching new clinical trials to leading scores of high-level advocacy meetings and leading efforts to elevate public awareness of global disease burdens, Sabin advances the important mission of improved global health. Sabin was founded to honor the legacy of Dr. Albert B. Sabin, the developer of the oral polio vaccine that has successfully brought the disease to the brink of eradication.



Developing New Vaccines Vaccines are among the most economical and effective medical technologies available today. Yet, there is an urgent need for new and more effective vaccines to fight diseases that primarily impact those in poverty. Product development partnerships (PDPs) provide a valuable model for vaccine development by convening public, private and academic partners who each contribute something different – from technical expertise, to manufacturing capabilities or funding – to the development and production of safe, effective vaccines. The Sabin PDP is a leader in the field, with more than a decade of experience in vaccine research and development for neglected tropical diseases that infect hundreds

of millions of people in poor and underserved communities. The Sabin PDP is the only partnership advancing vaccine candidates to prevent human hookworm – an intestinal worm infection that affects more than 700 million people around the world. In addition, the Sabin PDP is spearheading vaccine research and development projects targeting diseases such as schistosomiasis, severe acute respiratory syndrome (SARS), Chagas disease, leishmaniasis, ascariasis, trichuriasis, onchocerciasis and West Nile virus.

Learn more about our vaccine development program and the Sabin PDP partners at www.sabin.org/pdp



Vaccine-preventable diseases cause 1.5 million child deaths and countless cases of illness every year.

This can and must change.

Promoting Immunization Sabin is dedicated to reducing the burden of vaccine-preventable diseases. We also lay the groundwork for introducing new vaccines in endemic regions for diseases such as dengue fever. Technological advancements in vaccine development are spawning a new generation of increasingly powerful vaccines, including therapeutic vaccines, which have the potential to save millions of lives and alleviate unnecessary illness every year. But, they must be made available to everyone.

Education Sabin educates leaders from national governments, the private sector, media and civil society organizations on the value of immunization and encourages collaboration among all development partners on vaccine issues. Each year, Sabin coordinates symposia, conferences and peer exchanges on immunization in order to improve global awareness, access, policy and action.


Advocacy Sabin leads a host of immunization initiatives, including:

We are working to expand access to vaccines for:

∞ Coalition against Typhoid (CaT) Secretariat ∞ Dengue Vaccine Initiative (DVI) ∞ International Association of Immunization Managers (IAIM) ∞ ProVac International Working Group (IWG) ∞ ROTA Council ∞ Sustainable Immunization Financing (SIF)

∞ Typhoid ∞ Paratyphoid Fever ∞ Pneumococcal Disease ∞ Meningococcal Disease ∞ Human Papillomavirus (HPV) ∞ Pertussis ∞ Polio ∞ Measles ∞ Rotavirus ∞ Rubella

Together, these initiatives help countries make informed vaccine policy decisions, access new vaccines and expand disease control efforts.

Learn more about our our work in advocacy and education at www.sabin.org/VAE


Seven NTDs ∞ Hookworm ∞ Ascariasis (roundworm) ∞ Trichuriasis (whipworm) ∞ Lymphatic filariasis (elephantiasis) ∞ Onchocerciasis (river blindness) ∞ Schistosomiasis (snail fever) ∞ Trachoma

Controlling and Eliminating Neglected Tropical Diseases One in six people worldwide, including more than half a billion children, are infected with neglected tropical diseases (NTDs). The Global Network for Neglected Tropical Diseases, a Sabin initiative, is working to raise the awareness, political will and funding necessary to control and eliminate the seven most common NTDs. These diseases cause blindness, malnutrition and anemia, and they create serious health risks for women of reproductive age. NTDs contribute to poverty by reducing school attendance among children and worker productivity among adults.

The solution is within reach! For only 50 cents per person annually, a packet of pills – donated by the pharmaceutical companies – can be administered to treat all seven diseases. We work with our partners to raise awareness of neglected tropical diseases and help them deliver these solutions to at risk communities. Treatment Costs 50 Cents Per Person Per Year

50 ¢

Learn more about the Global Network for Neglected Tropical Diseases at www.globalnetwork.org




We believe that people everywhere have the right to good health that will empower them to lead successful lives. You can help us realize our vision of a world free of diseases of poverty.

What Your Contribution Means Your support will allow us to meet major milestones including: •

Bringing new vaccine candidates through clinical trials, licensure and manufacture, to tackle diseases such as hookworm, schistosomiasis, SARS, Chagas disease, leishmaniasis, ascariasis, trichuriasis, onchocerciasis and West Nile virus. Reducing the global prevalence of vaccine-preventable diseases that cause more than 1.5 million child deaths each year. Controlling and eliminating the seven most common neglected tropical diseases that infect one in six people worldwide by 2020.

We provide strong, responsible stewardship of donor funding. Sabin has received Charity Navigator’s highest four-star rating since 2006, placing us in the top two percent of evaluated charities, a ranking that reflects our transparency, accountability and efficiency. Sabin Vaccine Institute is a 501(c)(3) organization. Our Tax ID number is 06-1389829.

Please support our mission today. Web www.sabin.org/donate Email donate@sabin.org CFC # 91253


Sabin Vaccine Institute 2000 Pennsylvania Avenue, NW Suite 7100 Washington, DC 20006 Phone: +1 (202) 842-5025 Web: www.sabin.org Email: info@sabin.org @sabinvaccine facebook.com/sabinvaccine

Executive Leadership

Board of Trustees Axel Hoos, M.D., Ph.D. Interim Chairman Vice President, Oncology R&D, GlaxoSmithKline Pharmaceuticals Rt. Hon. Baroness Helene Hayman, GBE Immediate Past Lord Speaker of the House of Lords, United Kingdom Parliament Paul Maddon, M.D., Ph.D. Biotechnology entrepreneur and private investor Michael H. Posner Professor of Business and Society, NYU Stern School of Business Gary Rosenthal Partner in the Sterling Group, L.P. Immediate Past Chairman of the Board of Trustees, Texas Children’s Hospital

Phillip K. Russell, M.D. Past Chairman Major General, U.S. Army Medical Corps (Ret.) Marc Shapiro Non-Executive Chairman, Chase Bank of Texas Immediate Past Chairman of the Board of Trustees, Baylor College of Medicine Peter L. Thoren Executive Vice President, Access Industries, Inc. Michael E. Whitham Secretary and Treasurer Founding partner, Whitham, Curtis, Christofferson & Cook

Heloisa Sabin Honorary Trustee

Michael W. Marine, Ambassador (Ret.) Chief Executive Officer Peter J. Hotez, M.D., Ph.D. President Director, Sabin Vaccine Institute and Texas Children’s Hospital Center for Vaccine Development Jon Andrus, M.D. Executive Vice President Director, Vaccine Advocacy and Education Neeraj Mistry, M.D., M.P.H. Managing Director Global Network for Neglected Tropical Diseases Brian Davis, C.P.A. Chief Operating Officer Maria Elena Bottazzi, Ph.D. Deputy Director Sabin Product Development Partnership


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