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Discover Purposefully

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Crossing The Chasm

Crossing The Chasm

Align efforts toward patient benefit

Funding Agencies

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Aim more arrows directly at the target

Patient Benefit

Academic Collaborations Scientific Journals

Rationale: Pioneering biomedical research is at the heart of why Sanford Burnham Prebys Medical Discovery Institute exists. It is our core competency and most valuable differentiator. It is critical that our discovery research maintains the scientific freedom to explore new ideas and generate paradigm-shifting insights. But without alignment toward the common goal of patient benefit, our discovery efforts risk not reaching their full potential. The Discover Purposefully strategic theme is about making sure that the start of our medical innovation cycle is fueled with resolve and urgency to discover, not only for the advancement of our scientific knowledge, but for the ultimate goal of improving patient outcomes.

Strategic Concepts

Better Scientists Better Research Better Life™

Better Scientists Better Research Better Life™

Better Scientists Better Research Better Life™ Better Scientists Discover Purposefully Better Research Discover DevelopFor Better Life™ Better Life

Grow Build

Organize research teams around patient need

We will organize research programs into patient impact teams, focused on specific Discover Develop medical specialties or unmet needs, to spur innovation and drive outcomes through the intensity derived from a shared purpose. • Creates responsibility and autonomy for therapeutic target and candidate generation • Gro Build w Enhances collaboration across disciplines and subject matter expertise, both internal and external • Maintains scientific freedom to explore innovative research at the scientist level

Proactively seek translation opportunities

We need a system to proactively identify discoveries or assets with high potential for medical and commercial utility and provide the guidance to fast-track their development and maximize value.

• Leverages relevant subject matter experts to continually identify and evaluate assets with the greatest potential to impact patient care • Establishes development road maps and transition plans for promising discoveries and assets • Provides a mechanism to advise donors and investors on opportunities to support research and development

Incentivize success

We must establish feedback loops that properly reward discovery research focused on patient benefit.

• Ensures individual team members and the Institute are aligned to success criteria • Connects individuals and teams to the patient—and therefore, to our mission • Enables reinvestment with capital to further scientific freedom and fuel the next great discovery

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