Recently published research

Check out the research section on our website for a monthly listing of publications.

Access to Healthcare for Immigrant Children in Canada

Salami B, Mason A, Salma J, Yohani S, Amin M, Okeke-Ihejirika P, Ladha T. Published in International Journal of Environmental Research and Public Health. 2020, 17(9), 3320; doi: 10.3390/ ijerph17093320

Accuracy of interproximal enamel reduction during clear aligner treatment

De Felice ME, Nucci L, Fiori A, Flores-Mir C, Perillo L, Grassia V. Published in Progress in Orthodontics. 2020 Jul 28;21(1):28. doi: 10.1186/s40510-020- 00329-1.

Advancing public health communication in the era of empowered health consumerism: insights from dental hygienist-client interactions around community water fluoridation

Weijs C, Thawer S, Fundytus K, McLaren L. Published in Critical Public Health. 2020, Pages 1-13

Alveolar Bone Segmentation in Intraoral Ultrasonographs with Machine Learning

Nguyen KCT, Duong DQ, Almeida FT, Major PW, Kaipatur NR, Pham TT, Lou EHM, Noga M, Punithakumar K, Le LH. Published in Journal of Dental Research. 2020 May 11:22034520920593. doi: 10.1177/0022034520920593.

Antibiotic prophylaxis for implant placement: a systematic review of effects on reduction of implant failure

Kim AS, Abdelhay N, Levin L, Walters JD, Gibson MP. Published in British Dental Journal. 2020 Jun;228(12):943-951. doi: 10.1038/s41415-020- 1649-9.

Association between Psychological Stress and Periodontitis: A Systematic Review

Castro MML, Ferreira RDO, Fagundes NCF, Almeida APCPSC, Maia LC, Lima RR. Published in European Journal of Dentistry. Volume 14, Issue 1, 1 February 2020, Pages 171-179

Association between Tooth Loss and Stroke: A Systematic Review

Fagundes NCF, Couto RSD, Brandão APT, Lima LAO, Bittencourt LO, Souza-Rodrigues RD, Freire MAM, Maia LC, Lima RR. Published in Journal of Stroke & Cerebrovascular Diseases. 2020 Aug;29(8):104873. doi: 10.1016/j.jstrokecerebrovasdis.2020.104873. Epub 2020 Jun 8. PMID: 32689647

Association of cerebral malaria and TNF-α levels: a systematic review

Leão L, Puty B, Dolabela MF, Povoa MM, Né YGS, Eiró LG, Fagundes NCF, Maia LC, Lima RR. Published in BMC Infectious Diseases. 2020 Jun 23;20(1):442. doi: 10.1186/s12879-020-05107-2.

Augmented Reality Application to Develop a Learning Tool for Students: Transforming Cellphones into Flashcards

Sharmin N, Chow AK. Published in Healthcare Informatics Research. 2020 Jul;26(3):238-242. doi: 10.4258/hir.2020.26.3.238. Epub 2020 Jul 31.

Automated integration of facial and intra-oral images of anterior teeth

Li M, Xu X, Punithakumar K, Le LH, Kaipatur N, Shi B. Published in Computers in Biology and Medicine. Volume 122, July 2020, Article number 103794

Biomarkers in biological fluids in adults with periodontitis and/or obesity: A meta-Analysis

Brum RS, Duarte PM, De Luca Canto G, Flores Mir C, Benfatti CAM, Porporatti AL, Zimmermann GS. Published in Journal of Indian Society of Periodontology. Volume 24, Issue 3, May-June 2020, Pages 191-215

Bone dehiscence formation during orthodontic tooth movement through atrophic alveolar ridges.

Ramos AL, Dos Santos MC, de Almeida MR, Mir CF. Published in Angle Orthodontist. 2020 90 (3), pp. 321-329. DOI: 10.2319/063019-443.1

The Canadian Core Cariology Curriculum: Outcomes of a national symposium.

Tikhonova S, Jessani A, Girard F, Macdonald ME, De Souza G, Tam L, Eggert FM, Nguyen-Ngoc C, Morin N, Aggarwal N, Schroth RJ. Published in Journal of Dental Education. 2020 Jul 22. doi: 10.1002/ jdd.12313. Online ahead of print. PMID: 32700382

Combined Surgical and Orthodontic Treatments in Children with OSA: A Systematic Review

Templier L, Rossi C, Miguez M, Pérez JC, Curto A, Albaladejo A, Vich ML. Published in Journal of Clinical Medicine. 2020 Jul 26;9(8):E2387. doi: 10.3390/jcm9082387. PMID: 32722638

Comparison Between Removable and Fixed Devices for Nonskeletal Anterior Crossbite Correction in Children and Adolescents: A Systematic Review.

Jorge JO, Corradi-Dias L, Flores-Mir C, Pordeus IA, Paiva SM, Abreu LG. Published in Journal of Evidence-Based Dental Practice. 2020, Article number 101423.

Comparison of treatment outcomes with crowned and banded mandibular anterior repositioning appliance (MARA) in Class II pubertal subjects: A retrospective cohort study

Al-Jewair T, Ghorbaniparvar M, Franchi L, FloresMir C. Published in American Journal of Pathology. Volume 190, Issue 1, January 2020, Pages 206-221

Dental faculty and student views of didactic and clinical assessment. A qualitative description study

Perez A, Green JL, Starchuk C, Senior A, Compton SM, Gaudet-Amigo G, Lai H, Linke B, Patterson S. Published in European Journal of Dental Education. 2020 May 13. doi: 10.1111/eje.12541.

Dental Hierarchy of Needs’ in the COVID-19 Era – or Why Treat When It Doesn’t Hurt?.

Berlin-Broner Y, Levin L. Published in Oral Health and Preventive Dentistry. 18(2): 95

Detection of mast cells in ameloblastomas and odontogenic keratocysts

dos Santos ES, de Andrade RRA, Sampaio GC, Catunda RQ, Andrade ESDS. Published in Journal of Clinical and Experimental Dentistry. Volume 12, Issue 8, 1 August 2020, Pages e755-e761

Development, validation and application of a 3D printed model depicting adenoid hypertrophy in comparison to a Nasoendoscopy

Thereza-Bussolaro C, Lagravère M, PachêcoPereira C, Flores-Mir C. Published in Head & Face Medicine. Volume 16, Issue 1, 9 March 2020, Page 5

Differential expression of interferon-lambda receptor 1 splice variants determines the magnitude of the antiviral response induced by interferon-lambda 3 in human immune cells

Santer DM, Minty GES, Golec DP, Lu J, May J, Namdar A, Shah J, Elahi S, Proud D, Joyce M, Tyrrell DL, Houghton M. Published in PLoS Pathogens. 2020 Apr 30;16(4):e1008515. doi: 10.1371/journal. ppat.1008515. eCollection 2020 Apr.

Effect of Low Intensity Pulsed Ultrasound (LIPUS) on Tooth Movement and Root Resorption: A Prospective Multi-Center Randomized Controlled Trial

El-Bialy T, Farouk K, Carlyle TD, Wiltshire W, Drummond R, Dumore T, Knowlton K, Tompson B. Published in Journal of Clinical Medicine. 2020 Mar 16;9(3)

Effects of Intraligamentary Injection of Osteogenic-Induced Gingival Fibroblasts on Cementum Thickness in the Dog Model of Tooth Root Resorption

El-Bialy T, Hazan Molina H, Aizenbud Y, Qayyum W, Ali S, Aizenbud D. Published in Advances in Experimental Medicine and Biology. 2020 Jul 14. doi: 10.1007/5584_2020_551. Online ahead of print. PMID: 32661841

Erythroid precursors and progenitors suppress adaptive immunity and get invaded by SARS-CoV-2

Shahbaz S, Xu L, Osman M, Sligl W, Shields J, Joyce M, Tyrrell L, Oyegbami O, Elahi S. Preprinted in bioRxiv 2020.08.18.255927; doi: https://doi. org/10.1101/2020.08.18.255927

Evaluation of mandibular changes after rapid maxillary expansion: a CBCT study in youngsters with unilateral posterior crossbite using a surface-to-surface matching technique

Leonardi RM, Aboulazm K, Giudice AL, Ronsivalle V, D’Antò V, Lagravère M, Isola G. Published in Clinical Oral Investigations. 2020 Aug 2. doi: 10.1007/ s00784-020-03480-5.

Extraction force and its determinants for minimally invasive vertical tooth extraction

Dietrich T, Schmid I, Locher M, Addison O. Published in Journal of the Mechanical Behavior of Biomedical Materials. Volume 105, May 2020, Article number 103711

Failure rates among metal brackets cured with two high-intensity LED lightcuring lamps: an in vivo study.

Albertin SA, Pinzan-Vercelino CRM, Flores-Mir C, Gurgel JA. Published in European Journal of Orthodontics. 2020 Apr 7. pii: cjaa025

Galectin-9 and VISTA Expression Define Terminally Exhausted T Cells in HIV-1 Infection

Shahbaz S, Dunsmore G, Koleva P, Xu L, Houston S, Elahi S. Published in The Journal of Immunology. Vol. 204, Issue 7 1 Apr 2020

The glucocorticoids prednisone and dexamethasone differentially modulate T cell function in response to anti-PD-1 and anti-CTLA-4 immune checkpoint blockade.

Okoye IS, Xu L, Walker J, Elahi S. Published in Cancer Immunology, Immunotherapy. 2020 Apr 3

If we cannot measure it, we cannot improve it: Understanding measurement problems in routine oral/dental assessments in Canadian nursing homes—Part I

Hoben M, Yoon MN, Lu L, Estabrooks CA. Published in Gerodontology. Volume 37, Issue 2, 1 June 2020, Pages 153-163

If we cannot measure it, we cannot improve it: Understanding measurement problems in routine oral/dental assessments in Canadian nursing homes—Part II

Yoon MN, Lu L, Ickert C, Estabrooks CA, Hoben M. Published in Gerodontology. 2020

Immunological consequences of extramedullary erythropoiesis: immunoregulatory functions of CD71+ erythroid cells

Elahi S, Mashhouri S. Published in Haematologica. 2020 Apr 30. pii: haematol.2019.243063. doi: 10.3324/haematol.2019.243063.

Inhibition of neutrophil inflammatory mediator expression by azithromycin

Gibson MP, Walters JD. Published in Clinical Oral Investigations. 2020 May 21. doi: 10.1007/s00784- 020-03314-4.

Insights into Fibroblast Plasticity: Cellular Communication Network 2 Is Required for Activation of CancerAssociated Fibroblasts in a Murine Model of Melanoma

Tsang M, Quesnel K, Vincent K, Hutchenreuther J, Postovit L-M, Leask A. Published in American Journal of Pathology. Volume 190, Issue 1, January 2020, Pages 206-221

International Association of Dental Traumatology guidelines for the management of traumatic dental injuries: General introduction

Levin L, Day PF, Hicks L, O’Connell A, Fouad AF, Bourguignon C, Abbott PV. Published in Dental Traumatology. 2020 May 30. doi: 10.1111/edt.12574.

International Association of Dental Traumatology guidelines for the management of traumatic dental injuries: 1. Fractures and luxations

Bourguignon C, Cohenca N, Lauridsen E, Therese Flores M, O’Connell A, Day P, Tsilingaridis G, Abbott PV, Fouad AF, Hicks L, Ove Andreasen J, Cehreli ZC, Harlamb S, Kahler B, Oginni A, Semper M, Levin L. Published in Dental Traumatology. 2020 May 31. doi: 10.1111/edt.12578.

International Association of Dental Traumatology guidelines for the management of traumatic dental injuries: 2. Avulsion of permanent teeth

Fouad AF, Abbott PV, Tsilingaridis G, Cohenca N, Lauridsen E, Bourguignon C, O’Connell A, Flores MT, Day P, Hicks L, Andreasen JO, Cehreli ZC, Harlamb S, Kahler B, Oginni A, Semper M, Levin L. Published in Dental Traumatology. 2020 May 27. doi: 10.1111/edt.12573.

International Association of Dental Traumatology guidelines for the management of traumatic dental injuries: 3. Injuries in the Primary Dentition

Day P, Flores MT, O’Connell A, Abbott PV, Tsilingaridis G, Fouad AF, Cohenca N, Lauridsen E, Bourguignon C, Hicks L, Andreasen JO, Cehreli ZC, Harlamb S, Kahler B, Oginni A, Semper M, Levin L. Published in Dental Traumatology. 2020 May 27. doi: 10.1111/edt.12576.

In vitro assessment of an idealized nose for nasal spray testing: Comparison with regional deposition in realistic nasal replicas.

Chen J, Kiaee M, Martin AR, Finlay WH. Published in International Journal of Pharmaceutics. 2020 Apr 17;582:119341

Long term skeletal and dental changes between tooth-anchored versus Dresden bone-anchored rapid maxillary expansion using CBCT images in adolescents: Randomized clinical trial.

Davami K, Talma E, Harzer W, Lagravère MO. Published in International Orthodontics. 2020 Mar 31. pii: S1761-7227(20)30031-0

Mesenchymal Bmp7 Controls Onset of Tooth Mineralization: A Novel Way to Regulate Molar Cusp Shape

Malik Z, Roth DM, Eaton F, Theodor JM, Graf D. Published in Frontiers of Physiology. 2020 Jul 3;11:698. doi: 10.3389/fphys.2020.00698. eCollection 2020. PMID: 32719613 Free PMC article.

miRNAs as biomarkers of orofacial clefts: A systematic review

Mendes SMDA, Espinosa DDSG, Moreira PEDO, Marques D, Fagundes NCF, Ribeiro-dos-Santos Â. Published in Journal of Oral Pathology and Medicine. Volume 49, Issue 3, 1 March 2020, Pages 201-209

Neonatal and Children’s Immune System and COVID-19: Biased Immune Tolerance versus Resistance Strategy

Elahi S. Published in The Journal of Immunology. 2020 Aug 21:ji2000710. doi: 10.4049/ jimmunol.2000710.

nkx3.2 mutant zebrafish accommodate jaw joint loss through a phenocopy of the head shapes of Paleozoic jawless fish

Miyashita T, Baddam P, Smeeton J, Oel AP, Natarajan N, Gordon B, Palmer AR, Crump JG, Graf D, Allison WT. Published in Journal of Experimental Biology. 2020 Jun 11. pii: jeb.216945. doi: 10.1242/ jeb.216945.

One Step before 3D Printing-Evaluation of Imaging Software Accuracy for 3-Dimensional Analysis of the Mandible: A Comparative Study Using a Surfaceto-Surface Matching Technique

Lo Giudice A, Ronsivalle V, Grippaudo C, Lucchese A, Muraglie S, Lagravère MO, Isola G. Published in Materials. 2020 Jun 21;13(12). pii: E2798. doi: 10.3390/ma13122798.

Pediatric sleep-disordered breathing in the orthodontic population: Prevalence of positive risk and associations.

Abtahi S, Witmans M, Alsufyani NA, Major MP, Major PW. Published in American Journal of Orthodontics and Dentofacial Orthopedics. 2020 Apr;157(4):466- 473.e1

Polyacrylamide/Alginate doublenetwork tough hydrogels for intraoral ultrasound imaging

Yi J, Nguyen KT, Wang W, Yang W, Pan M, Lou E, Major PW, Le LH, Zeng H. Published in Journal of Colloid and Interface Science. 2020 Jun 6;578:598- 607. doi: 10.1016/j.jcis.2020.06.015.

Prevalence of dentofacial injuries among combat sports practitioners: A systematic review and meta-analysis

Polmann H, Melo G, Conti Réus J, Domingos FL, de Souza BDM, Padilha AC, Duque TM, Porporatti AL, Flores-Mir C, De Luca Canto G. Published in Dental Traumatology. Volume 36, Issue 2, 1 April 2020, Pages 124-140

Prevalence of mental disorders among elderly men: a systematic review and meta-analysis

Ribeiro GCA, Vieira WA, Herval ÁM, Rodrigues RPCB, Agostini BA, Flores-Mir C, Repeke CEP, Paranhos LR. Published in Sao Paulo Medical Journal. 2020 Jun 1. pii: S1516-31802020005009201. doi: 10.1590/1516-3180.2019.0454.r1.16012020.

Recommendations for approaching the introduction section of manuscripts and grant applications

Perez AJ, Compton SM, Green JL, Amin M. Published in Canadian Journal of Dental Hygiene. Volume 54, Issue 1, Feb 2020, Pages 42-44

Reliability and accuracy of segmentation of mandibular condyles from different three-dimensional imaging modalities: a systematic review

Kim JJ, Nam H, Kaipatur NR, Major PW, Flores-Mir C, Lagravere MO, Romanyk DL. Published in Dento maxillo facial radiology. Volume 49, Issue 5, 1 July 2020, Page 20190150

Saliva as an alternative to blood in the determination of uremic state in adult patients with chronic kidney disease: a systematic review and meta-analysis

Rodrigues RPCB, de Andrade Vieira W, Siqueira WL, Blumenberg C, de Macedo Bernardino Í, Cardoso SV, Flores-Mir C, Paranhos LR. Published in Clinical Oral Investigations. 2020 May 23. doi: 10.1007/ s00784-020-03340-2.

Selective Upregulation of CTLA-4 on CD8+ T Cells Restricted by HLAB*35Px Renders them to an Exhausted Phenotype in HIV-1 infection

Elahi S, Shahbaz S, Houston S. Published in PLoS Pathogens. 2020 Aug 6;16(8):e1008696. doi: 10.1371/journal.ppat.1008696. eCollection 2020 Aug.

Shortening of Overall Orthodontic Treatment Duration with Low-Intensity Pulsed Ultrasound (LIPUS)

Kaur H, El-Bialy T. Published in Journal of Clinical Medicine. 2020 May 1;9(5). pii: E1303. doi: 10.3390/ jcm9051303.

Stability of Class II corrections with removable and fixed functional appliances: A literature review

Moro A, Mattos CFP, Borges SW, Flores-Mir C, Topolski F. Published in Journal of the World Federation of Orthodontists. 2020 Jun;9(2):56-67. doi: 10.1016/j.ejwf.2020.04.003. Epub 2020 May 27. PMID: 32672656

Surgically accelerated orthodontic techniques and periodontal response: a systematic review

Rekhi U, Catunda RQ, Gibson MP. Published in European Journal of Orthodontics. 2020 Jan 15

A systematic review of the clinical and radiographic features of hybrid central giant cell granuloma lesions of the jaws

Alsufyani NA, Aldosary RM, Alrasheed RS, Alsaif RF. Published in Acta Odontologica Scandinavica. 2020 Jul 30:1-8. doi: 10.1080/00016357.2020.1797160. Online ahead of print. PMID: 32730731

Thinking Ecologically about Clinical Education in Dentistry

Perez A, Senior A, Green JL, Compton SM, Patterson S. Published in European Journal of Dental Education. 2020 Jan 24

The three-dimensional stable mandibular landmarks in patients between the ages of 12.5 and 17.1 years

Chen G, Al Awadi M, Chambers DW, LagravèreVich MO, Xu T, Oh H. Published in BMC Oral Health. Volume 20, Issue 1, 27 May 2020, Article number 153

Tridimensional upper airway assessment in male patients with OSA using oral advancement devices modifying their vertical dimension

Barbero M, Flores-Mir C, Blanco JC, Nuño VC, Casellas JB, Calvo Girado JL, Amezaga JA, De Carlos F. Published in Journal of Clinical Sleep Medicine. 2020 Jul 6. doi: 10.5664/jcsm.8666

The Use of High Frequency Vibration and Clear Aligners in Management of an Adult Patient with Class III Skeletal Malocclusion with Open Bite and Severe Bimaxillary Protrusion: Case Report

El-Bialy T. Published in Dentistry Journal (Basel). 2020 Jul 14;8(3):E75. doi: 10.3390/dj8030075. PMID: 32674423