K2 Complete

Help support your heart and vascular system

Protecting and nourishing our hearts with heart-healthy nutrients can help us stand a better chance against cardiovascular events. Created with Vitamin K2 and K1, discover the benefits of K2 Complete, a soft gel supplement for heart health.

CARDIOVASCULAR SUPPORT FROM HEART-HEALTHY VITAMIN K INGREDIENTS

TriVita’s K2 Complete contains three forms of Vitamin K: Vitamin K1 as phytonadione and Vitamin K2 as menaquinone-4 (MK-4) and menaquinone-7 (MK-7). Vitamin K2 and K1 are a group of fat-soluble vitamins widely researched for heart health benefits.1-5 Vitamin K deficiency can lead to calcification (mineral deposits) of vessel walls that has been associated with a higher risk of cardiovascular events. Vitamin K2 consumption may lower risk of vascular damage.1 It has also been found to be up to eight times more bioavailable than K1 and can remain active in the body for a longer period of time.2 Vitamin K1 can be found in plant-based foods such as kale, spinach and broccoli. Vitamin K2 is often missing in the Western diet as it is usually found in fermented foods.2,3

Vitamin K2 studies have shown:

• If at least 32 mcg of Vitamin K2 is present in the diet, then the risks for blood-vessel calcification and heart problems are significantly lowered.3 • High-intake of Vitamin K2 was associated with protection against cardiovascular events.4 • Long-term use of MK-7 supplements improved arterial stiffness, which is related to high blood pressure and hypertension in healthy postmenopausal women.5

THIS PRODUCT IS ALSO GREAT FOR:

HEALTHY INFLAMMATION SUPPORT MUSCULOSKELETAL SYSTEM SUPPORT NUTRITIONAL SUPPORT

K2 Complete

#31350 $24.99 Receive 100 VitaPoints! Suggested Use: Adults: Take one (1) soft gel daily.

K2 Complete

Quantity: 30 soft gels Serving size: 1 soft gel Ingredients: Vitamin K1 (as Phytonadione) 500 mcg, Vitamin K2 (as Menaquinone-4) 1,500 mcg, Vitamin K2 (as Menaquinone-7) 45 mcg. Other Ingredients: Medium Chain Triglyceride Oil, Olive Oil, Bovine Gelatin, Glycerin, Purified Water, Carob. Please Note: If you are taking anticoagulant or antiplatelet medications, or have a bleeding disorder, consult with your healthcare provider before taking this product.

References

1. Maresz K. Proper Calcium Use: Vitamin K2 as a Promoter of Bone and Cardiovascular Health. Integr Med (Encinitas). 2015;14(1):34-39. 2. Schurgers LJ, Teunissen KJ, Hamulyák K, Knapen MH, Vik H, Vermeer C. Vitamin K-containing dietary supplements: comparison of synthetic vitamin K1 and natto-derived menaquinone-7. Blood. 2007;109(8):3279-3283. doi:10.1182/blood-2006-08-040709 3. Geleijnse JM, Vermeer C, Grobbee DE, et al. Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease: the Rotterdam Study.

J Nutr. 2004;134(11):3100–3105. 4. Gast GC, de Roos NM, Sluijs I, et al. A high menaquinone intake reduces the incidence of coronary heart disease. Nutr Metab Cardiovasc Dis. 2009;19(7):504–510. 5. Knapen MH, Braam LA, Drummen NE, Bekers O, Hoeks AP, Vermeer C. Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial. Thromb Haemost. 2015;113(5):1135-1144. doi:10.1160/TH14-08-0675

How Nitric Oxide Helps with Healthy Circulation

We know that healthy circulation is important, but what we may not know is what to consume to help promote healthy circulation and blood flow. In terms of blood vessel health, nitric oxide is one of the most important molecules in the body. While nitric oxide itself may not be an ingredient to consume, some nutrients promote nitric oxide production. This is important because as we age, nitric oxide production decreases. We may feel this through lack of energy, high blood pressure and even cognitive decline. One study found that by age 70, most people will only produce 25% of nitric oxide through their blood vessels as compared to someone in their 20s.1 Since aging is considered one of the biggest risk factors for developing cardiovascularrelated health issues, it’s been found that cardiovascular protection decreases with age and a reduction in nitric oxide production.1

Additionally, Alzheimer’s disease has also been linked to nitric oxide decline.1 One out of every eight baby boomers will get Alzheimer’s disease after they turn 65 years old; at age 85, that risk grows to one in two.1 This is why healthy circulation and blood flow are so important. We want to be able to give our aging selves the best chance to live life to the fullest, and with more information at our fingertips than ever before, we have the tools to flourish as we age. Luckily for us, supplements are an exceptional tool to help the body create nitric oxide, which can also trickle down to help other areas of health. Supplements that support nitric oxide production can typically contain beetroot powder, L-Arginine, L-Arginine Alpha-Ketoglutarate, and L-Citrulline. These can be found in Nitric Oxide Plus. We’ll dive into the benefits of the ingredients in this powder supplement and how it can help the body produce nitric oxide and promote blood flow, later.

What is Nitric Oxide?

Think of nitric oxide as a messenger. It’s an essential messenger molecule that serves important vascular, as well as metabolic functions.2 It allows for blood, nutrients and oxygen to travel throughout the body effectively and efficiently.

Blood Flow Cognition1,3 Cellular Communication2 Antioxidation2 Libido4 Energy Normal Blood Pressure Endurance5 Immune Function6 Oxygenated Blood Breathing

References

1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018552/ 2.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425174/ 3.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390088/ 4.https://pubmed.ncbi.nlm.nih.gov/28178400/ 5.https://pubmed.ncbi.nlm.nih.gov/27600147/ 6.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1906415/

The Benefits of Healthy Blood Flow

High blood pressure occurs when the force of your blood pushing against the walls of your arteries is consistently too high. High blood pressure can lead to other health issues, such as heart problems and kidney problems. Consuming nitrates can help blood pressure because your body converts the nitrates to nitric oxide, which then causes blood vessels to relax and dilate, resulting in lower blood pressure. Various studies have shown nitrate to help lower blood pressure by increasing the production of nitric oxide.1,2 Additionally, it has been thought people with high blood pressure have an impaired ability to produce nitric oxide.3

Nitrates are also thought to promote endurance, and some studies suggest that endurance among athletes improved with nitrate consumption. One study found this through the consumption of beetroot juice.4,5 Nitric oxide can also be important for cognition, as it was found that a high-nitrate diet increased regional cerebral blood flow to the frontal lobe in older patients.6 When you hear of nitric oxide, you may be thinking of it as a gas. The gas form is called nitrous oxide and is sometimes referred to as “laughing gas.” That’s not what we’re talking about here. Nitric oxide’s function in the human body is crucial as it’s found naturally throughout the body and is necessary for healthy blood flow. So, how is nitric oxide formed and where can it be found? Nitric oxide is synthesized and released into the endothelial cells, which is a cell layer lining all blood vessels, with the help of nitric oxide synthases that convert arginine into citrulline which helps produce nitric oxide in the process.7 L-citrulline may also help to treat erectile dysfunction by increasing the production of nitric oxide.8 A form of L-citrulline, called citrulline malate, not only increases nitric oxide production but also can help decrease muscle soreness. One study analyzed 13 eligible articles that included a total of 206 participants. The most frequent dosage used in the studies was 8g of citrulline malate. Citrulline supplementation significantly reduced the rating of perceived exertion and muscle soreness 24 hours and 48 hours after post-exercise.9

As muscle soreness can get in the way of daily activities, looking at ingredients to help soothe symptoms can help us get back to pursuing our day-to-day interests. As you can see, increased blood flow serves as a link to other areas of health, helping to promote balance and well-being in the body.

References

1. https://pubmed.ncbi.nlm.nih.gov/24134873 2.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288952/ 3.https://pubmed.ncbi.nlm.nih.gov/17170603/ 4.https://pubmed.ncbi.nlm.nih.gov/34639501/ 5.https://pubmed.ncbi.nlm.nih.gov/34243756/ 6.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018552/ 7. https://pubmed.ncbi.nlm.nih.gov/18236016/ 8.https://pubmed.ncbi.nlm.nih.gov/21195829/ 9.https://pubmed.ncbi.nlm.nih.gov/33308806/

Sources to Promote Nitric Oxide Production

Did you know you produce nitric oxide by simply breathing? When breathing through your nose, your nasal passages release nitric oxide, which helps to widen blood vessels. This can help improve oxygen circulation in your body. Since nitric oxide is an unstable molecule that can degrade quickly in the bloodstream, it needs to be replenished.1 This can be done through consuming antioxidants, which is how antioxidation influences nitric oxide production. Besides breathing and antioxidants, beets are high in nitrates, which as previously mentioned, convert into nitric oxide. L-arginine is an amino acid, also known as a protein building block, naturally found in a variety of foods such as red meat, fish and dairy products. L-arginine produces nitric oxide in the body, as well as L-citrulline. L-citrulline is also an amino acid that’s found in meat and legumes. The easiest way to get these nutrients to help produce nitric oxide–besides food–is with supplements.

References

1. https://www.healthline.com/nutrition/how-to-increase-nitric-oxide# 2.https://jissn.biomedcentral.com/articles/10.1186/s12970-015-0086-7 3.https://pubmed.ncbi.nlm.nih.gov/23152216/

A Proprietary Combination of Ingredients to Improve Blood Flow

Nitric Oxide Plus improves blood flow through these ingredients: beetroot powder, L-Arginine, L-Arginine Alpha-Ketoglutarate and L-Citrulline. Beetroot powder is rich in nitrates which get converted to nitrite, which then gets converted to nitric oxide. L-Arginine is an amino acid that stimulates the dilation of blood vessels and nitric oxide production. L-Citrulline, another amino acid, has been indicated to be a second nitric oxide donor since it can be converted to L-arginine in the kidneys.2 Magnesium relaxes muscles to allow better blood flow. Magnesium is a mineral that can be found in greens, nuts, seeds, dry beans, whole grains, wheat germ, wheat and oat bran. Horse chestnut is commonly used to improve vein health, as it contains aescin, which may increase blood flow in veins and thin the blood.3 A supplement that can help support nitric oxide is important, and with our latest formulation, we want to be able to give you the convenience of a powder supplement for healthy blood flow support.