health briefs

Eat Lots of Fiber to Improve Melanoma Outcomes

A new type of immunotherapy that enables T-cells to fight cancer cells is proving hopeful for people with the deadly skin cancer melanoma, and a new study has found that a high-fiber diet improves the effectiveness of the therapy. Researchers from the University of Texas MD Anderson Cancer Center reported in Science that, by analyzing the gut microbiome in hundreds of patients, they found that higher dietary fiber intake was linked with disease nonprogression among patients receiving immune checkpoint blockade therapy compared to patients eating little fiber. The results were strongest in patients that ate the most dietary fiber, but did not take probiotics, a finding that was replicated with lab animals.

Avoid Formaldehyde to Sidestep Cognitive Problems

Workers exposed over years to formaldehyde may experience thinking and memory problems later in life, researchers at the University of Montpellier, in France, have concluded. Their study published in the journal Neurology surveyed and tested more than 75,000 people with an average age of 58. Of those, 8 percent were exposed to formaldehyde through their occupations as nurses; caregivers; medical technicians; workers in the textile, chemistry and metal industries; carpenters and cleaners. The risk of developing thinking and memory problems was an average of 17 percent higher in people that were exposed to formaldehyde on the job than those with no such exposure. People exposed to formaldehyde for 22 years or longer had a 21 percent higher risk of cognitive impairment.

Practice Good Dental Care to Lower Heart and Cognitive Risks

A whopping 47 percent of U.S. adults over 30 have periodontal disease, and the consequences can be severe for their physical and mental health, suggests a new study in the journal BMJ Open. Researchers from the UK University of Manchester followed 64,379 people diagnosed with periodontal disease, including gingivitis, marked by swollen and red gums, as well as periodontitis, in which gums pull away from the tooth and bone or teeth are lost. The subjects, with an average age of 44, were compared over popout/AdobeStock.com an average of three years to 251,161 people without the disease. Those with periodontal disease had a 37 percent higher risk of mental health problems, such as depression, anxiety and serious mental illness; a 33 percent higher risk of developing autoimmune diseases like arthritis, Type 1 diabetes and psoriasis; an 18 percent higher risk of cardiovascular disease, including heart failure, stroke and vascular dementia; and a 26 percent higher risk for developing Type 2 diabetes.

“This research provides further, clear evidence why healthcare professionals need to be vigilant for early signs of gum disease and how it can have wide-reaching implications for a person’s health, reinforcing the importance of taking a holistic approach when treating people,” says Caroline Aylott, head of research delivery at the University of Birmingham Versus Arthritis Centre for Musculoskeletal Ageing Research.